@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0772: (2015-12-04 )
MAEEINIMNDFTNNNNSSDSSIFQGKICPEDLNKAQEVNELKGVTEELFKKIELQKQEYEGLGKEASSEIQGMFTPVMLGDDNPTDGGIVEETLAELGKFFQSLLSEFEIELDPKTYEMINGKREKNWLAAIIKFLHDKLKELVEKVFSCDLSFDERVDKEIKELEEKLLSGGFSKEEEVAVLGKLEALRELKLKLQMAVAGWIVAMVAEIFAVELVVAAEGTGTAKEEDKKAEKTSSKKEVEVCKEIGIKVGEDEKLRILPISLFLIPARGQSNRLIIPPLKPEEQNLLRDSLKKMIHGPEHDVNRENCEVKETKVEENKQVEELIAVRPTASGQPATNSMELKDTQRDNSDWKEMKGQGKNNTCKKTLRQSNRGFVSNDNTSRRPAQSSVFSRETPEQLAQEYVFNGEASTQHATKSVSNRGSSGQPMKGSVVGSEYDFSTWSNAEYEAQQSSVNNAQPTSECNDVKVNNHVNSMGRAQGEAQSR
Atome Classification :
(20 SA)
------.........10........20........30.----.......40........50.....-----------...60........70.....-----...80........90-----.........100-----------.......110----....----...120...----------....130.......140.......150.......160.......170........180.....-..190.....---..200.----------------......210.......220-----.......230.......240...---....250...-....260........-270.......280....----------...290......--.300.---......-310.......320......--.330.......340.....-------...350.......360----------.........370-----------------.......380...--....---390..--------.....------------400.......410.......420---------------.......430.......440.......450.......460.......470.......480.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------MA
E
E
I
N
I
M
NDFTNNNNSSDSSIFQGKI
C
P
E
D
L
----
N
K
A
Q
E
V
N
E
L
K
G
V
T
E
E
L
F
K
K
I
E
L
Q
K
-----------
Q
E
Y
EGLG
K
E
A
S
S
E
I
Q
G
M
FT
P
-----
V
M
LGDDNPTDG
G
I
V
------
E
E
T
L
A
E
L
G
K
F
F
Q
-----------
S
L
L
S
E
F
E
I
EL----DP
K
T
----
Y
E
M
INGK
R
E
----------
K
N
W
L
A
A
I
I
K
F
L
H
D
K
L
K
E
L
V
E
K
V
FSCDLS
F
D
E
R
V
D
K
E
I
K
E
L
E
E
K
L
L
S-GGFS
K
E
E
E
V
A
V
L
G
K
L
E
-
A
L
R
E
L
K
L
K
L
Q
---
M
A
V
A
G
W
----------------
I
V
A
M
V
A
E
I
F
A
V
E
L
V
V
AAEG-----TGTA
K
E
E
D
K
K
AEKTS
S
K
K
E
V
E
V
C
---
K
EIGIKVGED-E
K
L
R
I
-
L
P
I
S
L
F
L
I
P-ARGQSN
R
L
I
IPPLKP
E
E
----------
Q
N
L
L
R
D
S
L
K
K
M
I--HGPEH---DVNREN-CEVKETKVE
E
N
K
Q
V
E
E
L
I
A--VRPTASGQPATNS-
M
E
L
KD-------TQRDNS
D
W
K
E
MKGQ------------GKN
N
T
C
K
K
T
L
R
Q-----------------SNRGFVSNDNTSR--RPAQ---SSVFS--------RE
T
P
E
------------
Q
L
A
Q
E
Y
VFNGEAST
Q
H
A
T
K
S
VSN---------------RGSSGQPM
K
G
S
V
VGSEYDFSTWSNAEY
E
A
Q
QSSVNNAQPTSECN
D
V
K
VNNHV
N
S
MGRAQGEAQSR
43
Fugue
72.34
20%
19
- C1 -
4UIR
3
OLHYD_ELIME
A:
[2-646]
NPITSK
F
D
K
V
L
N
A
S
S
E
Y
G
H
V
N
H
E
P
D
S
S
K
E
Q
Q
R
N
T
P
Q
K
S
MPFS
D
Q
I
G
N
Y
Q
R
N
K
G
I
P
V
Q
S
Y
D
N
S
K
I
Y
I
I
G
SG
I
A
G
M
S
A
A
Y
Y
F
I
R
D
G
H
V
P
A
K
N
I
T
F
L
E
Q
L
HIDGG
S
L
D
G
A
G
N
P
T
D
G
Y
I
I
R
G
G
R
E
M
D
M
T
Y
E
N
L
W
D
M
F
Q
DIPALEMPAPY
S
V
L
D
E
Y
R
L
I
N
----
D
N
D
S
N
Y
S
K
A
R
L
I
N
N
K
G
E
I
K
DFSKFGLN
K
M
D
Q
L
A
I
I
R
L
L
L
K
N
K
E
E
L
D
------
D
L
T
I
E
D
Y
F
S
E
S
F
L
K
------
S
-
N
F
W
T
F
W
R
T
M
F
A
F
E
N
W
H
-
S
L
L
E
L
K
L
Y
M
H
R
F
L
H
A
I
D
G
L
NDLSS
L
V
F
P
KYNQYDT
F
V
T
P
L
R
K
F
L
Q
E
K
G
V
N
I
H
L
N
-----
T
L
V
K
D
L
D
I
H
I
N
T
E
G
K
V
V
E
G
I
I
T
E
QDG
K
E
V
K
I
P
V
G
K
N
-
D
Y
V
I
V
-
T
T
G
S
M
T
E
D
T
-
F
Y
G
N
N
K
T
A
P
I
I
G
I
D
N
S
T
SGQSA
G
W
K
L
W
K
N
L
A
A
K
S
--
E
I
F
--
G
K
P
E
K
FCS
N
I
E
K
S
A
-
W
E
S
A
T
L
T
C
K
P
S
A
L
I
D
K
L
K
E
Y
S
V
N
D
P
Y
S
G
K
T
V
T
G
G
I
I
T
I
T
D
SNWL
M
S
F
T
C
N
R
Q
P
H
F
P
E
Q
P
D
D
V
L
V
L
W
V
Y
A
LFMD
K
E
G
N
Y
I
K
K
T
M
L
E
CT
G
D
E
I
L
A
E
L
C
Y
H
L
GIE
D
Q
L
E
N
V
Q
K
N
T
I
V
R
--
T
A
F
M
PYI
T
S
M
F
M
PRAKGD
R
P
R
V
V
P
E
GCKN
L
G
L
V
G
QFV
E
T
N
N
D
V
V
F
T
M
E
S
S
V
R
T
A
R
I
A
V
Y
K
L
L
NLN
K
Q
V
P
D
I
NPLQ
Y
D
I
R
H
L
L
K
A
A
K
T
L
N
D
D
K
P
F
V
G
E
G
L
L
R
K
V
L
K
G
T
Y
F
E
H
V
L
P
A
G
E
E
H
E
S
F
I
A
E
H
V
N
K
F
R
E
W
V
K
G
I
R
G
-
44
Fugue
60.55
12%
24
- C2 -
1LAM
6
?
?:
[160-484]
------
F
A
S
G
Q
N
L
A
R
R
L
M
E
T
P
-------------
A
N
E
M
----
T
P
T
K
F
A
E
I
V
E
E
N
L
K
S
A
S
I
K
T
D
V
F
I
-----------
R
P
K
S
W
I
E
E
Q
E
M
G
S
F
L
S
V
A
K
G
---------------------------------------------------
S
E
E
P
P
V
F
----
L
E
I
H
----
Y
K
G
S
P
N
A
S
E
----------
P
P
-------------
L
V
F
V
G
K
G
I
T
F
D
-------------------
S
-
G
G
I
S
I
K
A
A
A
----------
N
M
D
L
M
R
A
D
---
M
G
G
A
A
T
----------------
I
C
S
A
I
V
S
A
A
K
L
D
L
P
I
N
I
V
G
-----
L
A
P
L
C
E
N
M
P
S
G
K
A
N
K
P
G
D
V
V
R
A
R
---
N
G
K
T
I
Q
V
D
N
T
-
D
A
E
G
R
-
L
I
L
A
D
A
L
C
Y
-
A
H
T
F
N
P
K
V
I
I
N
A
A
----------------
T
L
T
G
A
M
D
I
A
L
--
G
S
G
A
T
---
G
V
F
T
N
S
-
S
W
L
W
N
K
L
F
E
A
S
I
E
T
G
D
R
V
W
--
R
M
P
L
--------------------------------------------------
F
E
H
Y
T
R
Q
V
I
D
-----------------
C
Q
L
A
D
V
N
N
I
G
K
Y
R
SA
G
A
C
T
---
A
A
A
F
L
--------
K
E
F
V
T
------------
H
P
K
W
A
H
L
D
I
A
G
V
M
T
N
K
D
E
V
P
Y
L
R
---------------
K
G
M
A
G
R
P
--------------------------------------------
T
R
T
L
I
E
F
L
F
R
F
S
Q
-
12
PsiBlast_PDB
56.96
36%
-10
- C3 -
2X51
-
MYO6_PIG
A:
[339-414]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
-------------
V
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
N
E
-----------------
V
H
Y
V
D
N
Q
D
C
I
D
L
I
--
E
A
R
L
---
V
G
I
L
D
--------
I
L
D
E
E
------------
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
H
F
---------------
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
E
L
2
PsiBlast_PDB
54.72
36%
-38
- C3 -
4DBP
-
MYO6_PIG
A:
[364-439]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
L
T
T
-
A
G
G
A
K
G
T
V
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
G
V
-----------------
N
E
V
H
Y
V
D
N
Q
D
C
I
D
--
L
I
E
A
---
R
L
V
G
I
--------
L
D
I
L
D
------------
E
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
---------------
H
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
1
PsiBlast_PDB
54.33
36%
-28
- C3 -
3L9I
-
MYO6_PIG
A:
[364-439]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
L
T
T
-
A
G
G
A
K
G
T
V
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
G
V
-----------------
N
E
V
H
Y
V
D
N
Q
D
C
I
D
--
L
I
E
A
---
R
L
V
G
I
--------
L
D
I
L
D
------------
E
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
---------------
H
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
17
PsiBlast_PDB
53.75
36%
-35
- C3 -
2BKI
-
MYO6_PIG
A:
[365-440]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
L
T
T
-
A
G
G
A
K
G
T
V
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
G
V
-----------------
N
E
V
H
Y
V
D
N
Q
D
C
I
D
--
L
I
E
A
---
R
L
V
G
I
--------
L
D
I
L
D
------------
E
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
---------------
H
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
41
Fugue
53.63
10%
15
* C4 *
1EZF
1
FDFT_HUMAN
A:
[8-340]
------------------------------------------------
N
S
L
K
T
C
Y
K
Y
L
N
Q
T
S
R
S
F
A
-----------
A
V
I
Q
A
L
D
G
E
M
R
N
A
V
C
I
F
Y
L
V
-----
L
R
A
L
D
T
L
E
D
D
M
T
I
S
------
V
E
K
K
V
P
L
L
H
N
F
H
-----------
S
F
L
Y
Q
P
D
W
R
F
MESK
E
K
D
R
----
Q
V
L
E
D
F
P
T
I
----------
S
L
E
F
R
N
L
A
E
K
Y
Q
T
V
I
A
D
I
C
R
R
M
G
I
G
M
A
E
F
L
D
K
H
V
T
S
E
Q
E
W
D
K
Y
C
H
Y
V
A
G
L
V
G
I
G
L
S
R
L
F
S
A
S
E
F
E
D
P
L
V
G
E
D
T
E
---
R
A
N
S
M
G
----------------
L
F
L
Q
K
T
N
I
I
R
D
Y
L
E
D
Q
Q
G
G
REFWP
Q
E
V
W
S
R
Y
V
K
K
L
G
D
F
A
K
P
E
N
I
D
L
A
---
V
Q
C
L
N
E
L
I
T
N
-
A
L
H
H
I
-
P
D
V
I
T
Y
L
S
R
L
R
N
Q
S
V
F
N
F
C
A
I
P
Q
V
M
A
I
----------
A
T
L
A
A
C
Y
N
N
Q
Q
V
--
F
K
G
A
V
---
K
I
D
A
T
N
---
M
P
A
V
K
A
I
I
Y
Q
Y
M
E
E
I
Y
H
--
R
I
P
D
S
D
P
S
S
S
K
T
R
-
Q
I
I
S
T
-------
I
R
T
Q
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
53.03
36%
-32
- C3 -
4PJN
1
?
A:
[364-439]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
----------
T
V
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
G
V
-----------------
N
E
V
H
Y
V
D
N
Q
D
C
I
D
--
L
I
E
A
---
R
L
V
G
I
--------
L
D
I
L
D
------------
E
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
---------------
H
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
7
PsiBlast_PDB
53.03
36%
-26
- C3 -
4PFO
3
?
A:
[364-439]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
-----------
V
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
G
V
-----------------
N
E
V
H
Y
V
D
N
Q
D
C
I
D
--
L
I
E
A
---
R
L
V
G
I
--------
L
D
I
L
D
------------
E
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
---------------
H
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
9
PsiBlast_PDB
52.64
36%
-28
- C3 -
4PJM
1
?
A:
[364-439]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
L
-----------
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
G
V
-----------------
N
E
V
H
Y
V
D
N
Q
D
C
I
D
--
L
I
E
A
---
R
L
V
G
I
--------
L
D
I
L
D
------------
E
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
---------------
H
F
R
L
S
I
P
R
K
S
K
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
E
L
8
PsiBlast_PDB
52.63
36%
-26
- C3 -
4PFP
-
?
A:
[364-439]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
-----------
V
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
G
V
-----------------
N
E
V
H
Y
V
D
N
Q
D
C
I
D
--
L
I
E
A
---
R
L
V
G
I
--------
L
D
I
L
D
------------
E
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
---------------
H
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
3
PsiBlast_PDB
52.29
36%
-30
- C3 -
2BKH
1
MYO6_PIG
A:
[364-439]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
L
T
T
-
A
G
G
A
K
G
T
V
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
G
V
-----------------
N
E
V
H
Y
V
D
N
Q
D
C
I
D
--
L
I
E
A
---
R
L
V
G
I
--------
L
D
I
L
D
------------
E
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
---------------
H
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
14
PsiBlast_PDB
52.27
36%
-21
- C3 -
4PJL
2
?
A:
[364-439]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
-----------
V
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
E
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
G
V
-----------------
N
E
V
H
Y
V
D
N
Q
D
C
I
D
--
L
I
E
A
---
R
L
V
G
I
--------
L
D
I
L
D
------------
E
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
---------------
H
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
5
PsiBlast_PDB
52.12
37%
-7
- C3 -
4DBR
-
MYO6_PIG
A:
[362-444]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
-------------
V
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
F
--
E
Y
F
E
H
N
S
F
E
Q
F
C
I
-
N
Y
C
N
E
-------
K
L
Q
Q
F
F
N
E
R
I
L
K
E
E
------------
Q
E
L
Y
Q
K
E
G
L
G
V
N
-----------------
E
V
H
Y
V
D
N
Q
D
C
I
D
L
--
I
E
A
R
---
L
V
G
I
L
--------
D
I
L
D
E
------------
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
H
---------------
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
E
6
PsiBlast_PDB
52.00
36%
-5
- C3 -
4DBQ
1
MYO6_PIG
A:
[338-413]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
--------------
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
G
V
-----------------
N
E
V
H
Y
V
D
N
Q
D
C
I
D
--
L
I
E
A
---
R
L
V
G
I
--------
L
D
I
L
D
------------
E
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
---------------
H
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
16
PsiBlast_PDB
51.79
36%
-2
- C3 -
4PJJ
-
?
A:
[338-413]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
M
V
----------------
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
G
V
-----------------
N
E
V
H
Y
V
D
N
Q
D
C
I
D
--
L
I
E
A
---
R
L
V
G
I
--------
L
D
I
L
D
------------
E
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
---------------
H
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
13
PsiBlast_PDB
51.62
36%
-17
- C3 -
2V26
-
MYO6_PIG
A:
[361-436]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
------------
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
G
V
-----------------
N
E
V
H
Y
V
D
N
Q
D
C
I
D
--
L
I
E
A
---
R
L
V
G
I
--------
L
D
I
L
D
------------
E
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
---------------
H
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
11
PsiBlast_PDB
51.25
36%
-10
- C3 -
4PK4
-
?
A:
[364-439]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
------------
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
-
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
--
F
E
Y
F
E
H
N
S
F
E
Q
F
C
-
I
N
Y
C
N
-------
E
K
L
Q
Q
F
F
N
E
R
I
L
K
E
------------
E
Q
E
L
Y
Q
K
E
G
L
G
V
-----------------
N
E
V
H
Y
V
D
N
Q
D
C
I
D
--
L
I
E
A
---
R
L
V
G
I
--------
L
D
I
L
D
------------
E
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
---------------
H
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
4
PsiBlast_PDB
50.98
37%
-35
- C3 -
4E7Z
-
?
A:
[374-456]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
L
----------
V
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
F
--
E
Y
F
E
H
N
S
F
E
Q
F
C
I
-
N
Y
C
N
E
-------
K
L
Q
Q
F
F
N
E
R
I
L
K
E
E
------------
Q
E
L
Y
Q
K
E
G
L
G
V
N
-----------------
E
V
H
Y
V
D
N
Q
D
C
I
D
L
--
I
E
A
R
---
L
V
G
I
L
--------
D
I
L
D
E
------------
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
H
---------------
F
R
L
S
I
P
R
K
S
K
L
A
I
H
R
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
E
15
PsiBlast_PDB
50.79
37%
-27
- C3 -
4E7S
1
?
A:
[374-456]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
K
S
T
Q
A
L
E
Y
C
---
A
E
L
---
L
G
L
D
Q
D
D
L
R
V
S
L
T
T
R
V
M
L
----------
V
I
K
V
P
L
K
V
E
Q
----------
A
N
N
A
R
D
A
L
A
K
T
V
Y
S
H
L
F
D
H
---
V
V
N
R
V
N
Q
C
F
P
F
E
T
S
S
Y
F
I
G
V
L
D
I
A
G
F
--
E
Y
F
E
H
N
S
F
E
Q
F
C
I
-
N
Y
C
N
E
-------
K
L
Q
Q
F
F
N
E
R
I
L
K
E
E
------------
Q
E
L
Y
Q
K
E
G
L
G
V
N
-----------------
E
V
H
Y
V
D
N
Q
D
C
I
D
L
--
I
E
A
R
---
L
V
G
I
L
--------
D
I
L
D
E
------------
E
N
R
L
P
Q
P
S
D
Q
H
F
T
S
A
V
H
Q
K
H
K
D
H
---------------
F
R
L
S
I
P
R
K
S
K
L
E
N
I
R
D
D
E
G
F
I
I
R
H
F
A
G
A
V
C
Y
E
T
T
Q
F
V
E
K
N
N
D
A
L
H
M
S
L
E
S
L
I
C
E
S
R
D
K
F
I
R
E
L
F
E