@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA1201: (2016-03-23 )
MTLLTRIKTETILLESDIKELIDILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLINTMYPHQPCYEGAMCVCGTGGDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTDLLNQMNIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQPVRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTEDGEIKNYTLNATDYGLKHAPNSDFKGGSPEENLAISLNILNGKDQSSRRDVVLLNAGLSLYVAEKVDTIAEGIELATTLIDNGEALKKYHQMRGE
Atome Classification :
(43 SA)
--.........10........20........30........40........50........60.....-...--70........80........90........100.......110...-....120......-.130-...-....-.140.......150.......160.......170.......180.......190........200.......210.......220.......230.......240.......250.......260.......270.......280....---------...290.......-------300..--.....310.......320---.......330
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--M
T
L
L
T
R
IK
T
E
T
I
L
L
E
S
D
I
K
E
L
I
D
I
L
ISPSIGT
D
I
K
Y
E
L
L
S
S
Y
S
E
R
E
I
Q
Q
Q
E
L
T
Y
I
V
R
S
L
I
N
TMYPH-QPC--YEG
A
M
C
V
CGTGGDKSN
S
F
N
I
S
T
T
V
A
F
V
V
A
SA
G
V
K
V
I
KHGNKSITSN-SGS
T
D
L
L
N
QMN
I
Q
-
T
T
-T-VDD-TPNQ-LNEK
D
L
V
F
I
GATESY
P
I
M
K
Y
M
Q
P
V
R
K
MIGK
P
T
I
L
N
L
V
G
P
LIN
P
Y
H
L
T
Y
Q
M
V
G-VFD
P
T
K
L
K
L
V
A
K
T
I
K
D
LGRK
R
A
I
V
L
HGANGMDEATLSGD
N
L
I
Y
E
LTEDG
E
I
K
N
Y
T
LNATDYGLKHAPNSDFKGGSPEE
N
L
A
I
S
L
N
I
LNGKDQSSRR---------
D
V
V
L
LNAG
L
S
L
Y
V
-------
A
E
K
V
D
--
T
I
A
E
G
I
E
L
A
T
T
LIDN
G
E
A
---
L
K
K
Y
H
Q
MRGE
70
HHSearch
97.30
32%
-97
- C13 -
2ELC
4
TRPD_THET8
A:
[2-325]
---
D
A
V
K
K
A
I
L
G
E
V
L
E
E
E
E
A
Y
E
V
M
R
A
L
M
A
G
E
V
S
P
V
R
A
A
G
L
L
V
A
L
S
L
R
G
E
R
P
H
E
I
A
A
M
A
R
A
M
R
E
A
A
R
P
L
-
R
V
H
--
R
R
P
L
L
D
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
-
A
G
S
A
D
L
L
E
A
L
G
V
D
-
L
E
-
A
P
P
E
R
-
V
G
E
A
-
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
-
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
A
-
R
G
L
V
V
H
G
-
E
G
A
D
E
L
V
L
-
G
E
N
R
V
V
E
V
G
-
K
G
---
A
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
A
A
L
A
R
R
L
L
K
G
E
E
K
G
P
L
A
---------
D
A
V
A
L
A
A
G
A
G
F
Y
A
-------
A
G
K
T
P
--
S
L
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
---
Y
L
L
L
E
R
Y
V
A
-
68
HHSearch
96.47
34%
-95
- C13 -
1VQU
2
TRPD2_NOSS1
A:
[28-370]
--
Y
L
L
L
Q
Q
L
I
D
G
E
S
L
S
R
S
Q
A
A
E
L
M
Q
G
W
L
S
E
A
V
P
P
E
L
S
G
A
I
L
T
A
L
N
F
K
G
V
S
A
D
E
L
T
G
M
A
E
V
L
Q
S
Q
S
K
M
----
T
NS
P
F
S
I
I
D
T
C
G
T
G
---
S
S
T
F
N
I
S
T
A
V
A
F
V
A
A
A
Y
G
V
P
V
A
K
H
G
N
R
--
S
S
L
-
T
G
S
A
D
V
L
E
A
L
G
V
N
-
L
G
-
A
S
P
E
K
-
V
Q
A
A
-
L
Q
E
V
G
I
T
F
L
F
A
P
G
W
H
P
A
L
K
A
V
A
T
L
R
R
T
L
R
I
R
T
V
F
N
L
L
G
P
L
V
N
P
L
R
P
T
G
Q
V
V
G
-
L
F
T
P
K
L
L
T
T
V
A
Q
A
L
D
N
L
G
K
Q
K
A
I
V
L
H
G
R
E
R
L
D
E
A
G
L
G
D
L
T
D
L
A
V
L
S
-
D
G
E
L
Q
L
T
T
I
N
P
Q
E
V
G
V
T
P
A
P
I
G
A
L
R
G
G
D
V
Q
E
N
A
E
I
L
K
A
V
L
Q
G
K
G
T
Q
A
Q
Q
---------
D
A
V
A
L
N
A
A
L
A
L
Q
V
-------
A
G
A
V
P
LL
D
H
A
Q
G
V
S
V
A
K
E
I
L
Q
T
G
T
A
---
W
A
K
L
A
Q
L
V
Y
-
84
Fugue
94.01
30%
-97
- C13 -
1KHD
-
?
A:
[12-344]
TH
Q
P
I
L
E
K
L
F
K
S
Q
S
M
T
Q
E
E
S
H
Q
L
F
A
A
I
V
R
G
E
L
E
D
S
Q
L
A
A
A
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
Q
P
F
-
P
R
P
--
D
Y
D
F
A
D
I
V
G
T
G
G
D
G
T
N
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
R
C
---------
D
L
L
Q
A
F
G
I
R
-
L
D
M
S
-
A
E
D
-
S
R
Q
A
-
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
-
V
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
A
A
V
V
H
G
-
G
G
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
-
N
G
E
I
E
S
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
R
D
I
L
A
R
L
L
Q
G
K
G
D
A
A
H
A
---------
R
Q
V
A
A
N
V
A
L
L
L
K
L
-------
F
G
Q
-
D
--
N
L
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
---
F
E
R
V
T
A
L
A
A
R
69
HHSearch
93.35
30%
-99
- C13 -
1KHD
-
?
A:
[14-343]
--
Q
P
I
L
E
K
L
F
K
S
Q
S
M
T
Q
E
E
S
H
Q
L
F
A
A
I
V
R
G
E
L
E
D
S
Q
L
A
A
A
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
Q
P
F
-
P
R
P
--
D
Y
D
F
A
D
I
V
G
T
G
G
D
G
T
N
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
R
---------
C
D
L
L
Q
A
F
G
I
R
-
L
D
-
M
S
A
E
D
-
S
R
Q
A
-
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
-
V
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
A
A
V
V
H
G
-
G
G
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
-
N
G
E
I
E
S
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
R
D
I
L
A
R
L
L
Q
G
K
G
D
A
A
H
A
---------
R
Q
V
A
A
N
V
A
L
L
L
K
L
-------
F
G
Q
D
---
N
L
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
---
F
E
R
V
T
A
L
A
A
-
1
PsiBlast_PDB
90.94
35%
-79
- C13 -
1KGZ
4
?
A:
[52-337]
----------------------------------------
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
Q
P
F
P
R
P
D
--
Y
D
F
A
D
I
V
-
G
T
G
G
D
G
T
N
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
R
S
-----
A
G
S
C
D
L
L
Q
A
F
G
I
R
L
D
M
-
S
-
A
E
D
-
S
R
Q
A
-
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
-
V
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
A
A
V
V
H
G
-
G
G
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
-
N
G
E
I
E
S
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
R
D
I
L
A
R
L
L
Q
G
K
G
D
A
A
H
A
---------
R
Q
V
A
A
N
V
A
L
L
L
K
L
-------
F
G
Q
-
D
--
N
L
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
---
F
E
R
-------
2
PsiBlast_PDB
90.29
35%
-83
- C13 -
1KHD
-
?
A:
[52-337]
----------------------------------------
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
Q
P
F
P
R
P
D
--
Y
D
F
A
D
I
V
-
G
T
G
G
D
G
T
N
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
R
---------
C
D
L
L
Q
A
F
G
I
R
L
D
M
-
S
-
A
E
D
-
S
R
Q
A
-
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
-
V
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
A
A
V
V
H
G
-
G
G
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
-
N
G
E
I
E
S
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
R
D
I
L
A
R
L
L
Q
G
K
G
D
A
A
H
A
---------
R
Q
V
A
A
N
V
A
L
L
L
K
L
-------
F
G
Q
-
D
--
N
L
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
---
F
E
R
-------
21
PsiBlast_CBE
89.46
35%
-78
- C13 -
1KGZ
4
?
B:
[52-337]
----------------------------------------
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
Q
P
F
P
R
P
D
--
Y
D
F
A
D
I
V
-
G
T
G
G
D
G
T
N
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
R
S
V
---L
A
G
S
C
D
L
L
Q
A
F
G
I
R
L
D
M
-
S
-
A
E
D
-
S
R
Q
A
-
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
-
V
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
A
A
V
V
H
G
-
G
G
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
-
N
G
E
I
E
S
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
R
D
I
L
A
R
L
L
Q
G
K
G
D
A
A
H
A
---------
R
Q
V
A
A
N
V
A
L
L
L
K
L
-------
F
G
Q
-
D
--
N
L
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
---
F
E
R
-------
71
HHSearch
87.76
26%
-98
- C13 -
1O17
-
TRPD_SULSO
A:
[4-328]
--
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
I
K
I
-
D
V
P
----
N
A
I
D
T
A
G
----
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
-
L
V
N
P
V
A
K
H
G
N
R
A
V
S
G
K
-
S
G
S
A
D
V
L
E
A
L
G
Y
N
-
I
I
-
V
P
P
E
R
-
A
K
E
L
-
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
-
V
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
I
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
-
K
R
G
I
E
E
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
G
K
-
D
E
H
V
A
---------
E
F
I
K
I
N
T
A
V
A
L
F
A
-------
L
D
R
V
G
--
D
F
R
E
G
Y
E
Y
A
D
H
L
I
E
--
K
S
---
L
D
K
L
N
E
I
I
S
-
22
PsiBlast_CBE
84.26
36%
-76
- C13 -
2ELC
2
TRPD_THET8
D:
[76-323]
--------------------------------------------------------------------------------
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
-
A
G
S
A
D
L
L
E
A
L
G
V
D
-
L
E
-
A
-
P
P
E
-
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
-
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
-
A
R
G
L
V
V
H
G
-
E
G
A
D
E
L
V
L
-
G
E
N
R
V
V
E
V
G
K
G
----
A
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
A
A
L
A
R
R
L
L
K
G
E
E
K
G
P
L
A
---------
D
A
V
A
L
A
A
G
A
G
F
Y
A
-------
A
G
K
T
P
--
S
L
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
YLL
L
E
R
Y
------
4
PsiBlast_PDB
84.04
36%
-78
- C13 -
1V8G
-
TRPD_THETH
A:
[76-323]
--------------------------------------------------------------------------------
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
-
A
G
S
A
D
L
L
E
A
L
G
V
D
-
L
E
-
A
-
P
P
E
-
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
-
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
-
A
R
G
L
V
V
H
G
-
E
G
A
D
E
L
V
L
-
G
E
N
R
V
V
E
V
G
K
G
----
A
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
A
A
L
A
R
R
L
L
K
G
E
E
K
G
P
L
A
---------
D
A
V
A
L
A
A
G
A
G
F
Y
A
-------
A
G
K
T
P
--
S
L
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
Y
L
L
L
E
R
Y
------
5
PsiBlast_PDB
83.95
36%
-75
- C13 -
2ELC
4
TRPD_THET8
A:
[76-323]
--------------------------------------------------------------------------------
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
-
A
G
S
A
D
L
L
E
A
L
G
V
D
-
L
E
-
A
-
P
P
E
-
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
-
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
-
A
R
G
L
V
V
H
G
-
E
G
A
D
E
L
V
L
-
G
E
N
R
V
V
E
V
G
K
G
----
A
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
A
A
L
A
R
R
L
L
K
G
E
E
K
G
P
L
A
---------
D
A
V
A
L
A
A
G
A
G
F
Y
A
-------
A
G
K
T
P
--
S
L
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
Y
L
L
L
E
R
Y
------
23
PsiBlast_CBE
83.72
36%
-74
- C13 -
2ELC
3
TRPD_THET8
C:
[76-323]
--------------------------------------------------------------------------------
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
-
A
G
S
A
D
L
L
E
A
L
G
V
D
-
L
E
-
A
-
P
P
E
-
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
-
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
-
A
R
G
L
V
V
H
G
-
E
G
A
D
E
L
V
L
-
G
E
N
R
V
V
E
V
G
K
G
----
A
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
A
A
L
A
R
R
L
L
K
G
E
E
K
G
P
L
A
---------
D
A
V
A
L
A
A
G
A
G
F
Y
A
-------
A
G
K
T
P
--
S
L
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
YLL
L
E
R
Y
------
24
PsiBlast_CBE
82.62
36%
-78
- C13 -
2ELC
4
TRPD_THET8
B:
[76-323]
--------------------------------------------------------------------------------
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
-
A
G
S
A
D
L
L
E
A
L
G
V
D
-
L
E
-
A
-
P
P
E
-
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
-
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
-
A
R
G
L
V
V
H
G
-
E
G
A
D
E
L
V
L
-
G
E
N
R
V
V
E
V
G
K
G
----
A
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
A
A
L
A
R
R
L
L
K
G
E
E
K
G
P
L
A
---------
D
A
V
A
L
A
A
G
A
G
F
Y
A
-------
A
G
K
T
P
--
S
L
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
YLL
L
E
R
Y
------
39
PsiBlast_CBE
82.38
32%
-79
- C13 -
4N8Q
1
TRPD_MYCTU
B:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
----
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
SR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
17
PsiBlast_PDB
82.31
32%
-76
- C13 -
3QR9
2
TRPD_MYCTU
A:
[101-355]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
SR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
67
PsiBlast_CBE
82.12
32%
-66
- C13 -
4GIU
9
TRPD_MYCTU
A:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
LSSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
56
PsiBlast_CBE
82.06
32%
-69
- C13 -
3QQS
4
TRPD_MYCTU
B:
[101-355]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
GLSSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
60
PsiBlast_CBE
81.80
32%
-70
- C13 -
4OWQ
6
TRPD_MYCTU
A:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
SSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
49
PsiBlast_CBE
81.80
32%
-65
- C13 -
3R6C
5
TRPD_MYCTU
A:
[101-355]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
LSSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
48
PsiBlast_CBE
81.74
32%
-68
- C13 -
3R6C
5
TRPD_MYCTU
B:
[101-355]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
HAGLSSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
64
PsiBlast_CBE
81.62
32%
-72
- C13 -
4OWM
5
TRPD_MYCTU
B:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
--
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
SR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
50
PsiBlast_CBE
81.56
32%
-71
- C13 -
3QSA
4
TRPD_MYCTU
B:
[101-355]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
HAGLSSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
18
PsiBlast_PDB
81.53
32%
-71
- C13 -
3QQS
4
TRPD_MYCTU
A:
[101-355]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
SSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
36
PsiBlast_CBE
81.41
32%
-66
- C13 -
4GKM
9
TRPD_MYCTU
B:
[103-357]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
HAGLSSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
66
PsiBlast_CBE
81.40
32%
-67
* C13 *
4GIU
8
TRPD_MYCTU
B:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
HAGLSSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
63
PsiBlast_CBE
81.35
32%
-73
- C13 -
4OWN
8
TRPD_MYCTU
B:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
-
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
SR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
61
PsiBlast_CBE
81.34
32%
-68
- C13 -
4OWO
7
TRPD_MYCTU
B:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
SR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
55
PsiBlast_CBE
81.30
32%
-72
- C13 -
3QQS
5
TRPD_MYCTU
C:
[101-355]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
-
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
HAGLSSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
12
PsiBlast_PDB
81.26
32%
-67
- C13 -
4GKM
7
TRPD_MYCTU
A:
[103-357]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
LSSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
58
PsiBlast_CBE
81.24
32%
-66
- C13 -
4OWU
6
TRPD_MYCTU
B:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
HAGLSSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
65
PsiBlast_CBE
81.17
32%
-69
- C13 -
4OWM
5
TRPD_MYCTU
A:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
SSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
62
PsiBlast_CBE
81.16
32%
-68
- C13 -
4OWO
6
TRPD_MYCTU
A:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
SR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
20
PsiBlast_PDB
81.10
32%
-68
- C13 -
3QSA
4
TRPD_MYCTU
A:
[101-355]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
SSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
59
PsiBlast_CBE
80.75
32%
-68
- C13 -
4OWU
6
TRPD_MYCTU
A:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
S
SR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
38
PsiBlast_CBE
80.28
32%
-70
- C13 -
4N93
5
TRPD_MYCTU
B:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
HAGLSS-
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
3
PsiBlast_PDB
80.26
34%
-87
- C13 -
4YI7
1
?
A:
[96-348]
--------------------------------------------------------------------------------
I
V
G
T
G
G
D
--
N
L
F
N
V
S
T
A
S
S
F
V
I
A
A
A
G
A
T
I
A
K
H
G
N
R
--------
S
S
D
L
L
E
Q
A
G
I
N
L
D
L
-
D
-
M
Q
Q
-
T
E
R
C
-
I
R
E
M
G
V
G
F
L
F
A
------
M
K
Y
A
V
G
P
R
R
E
L
G
I
R
S
I
F
N
L
L
G
P
L
T
N
P
A
G
V
K
R
F
V
I
G
-
V
F
S
D
E
L
C
R
P
I
A
E
V
M
K
Q
L
G
A
E
H
V
M
V
V
H
S
K
D
G
L
D
E
I
S
L
A
S
Q
T
Y
I
A
E
L
-
K
N
G
E
V
T
E
W
V
L
N
P
E
D
V
N
I
---
P
S
Q
T
L
S
G
L
I
V
E
D
S
N
A
-
S
L
K
L
I
--
K
D
A
L
G
R
K
KS
D
I
G
E
K
A
A
N
M
I
A
L
N
A
G
A
G
I
Y
V
-------
S
G
L
A
T
--
S
Y
K
Q
G
V
A
L
A
H
D
I
I
Y
G
G
Q
A
---
L
E
K
-------
11
PsiBlast_PDB
80.09
32%
-66
- C13 -
1ZVW
4
TRPD_MYCTU
A:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
LSSR
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
46
PsiBlast_CBE
79.95
32%
-68
- C13 -
3R88
4
TRPD_MYCTU
B:
[101-355]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
HAGLS--
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
47
PsiBlast_CBE
79.61
32%
-67
- C13 -
3R88
3
TRPD_MYCTU
A:
[101-355]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
LS--
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
41
PsiBlast_CBE
79.10
32%
-68
- C13 -
3UU1
5
TRPD_MYCTU
C:
[101-355]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
----
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
HAGL----
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
40
PsiBlast_CBE
78.93
32%
-68
- C13 -
4N5V
6
TRPD_MYCTU
B:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
HAGLSS-
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
14
PsiBlast_PDB
78.92
32%
-66
- C13 -
4N5V
7
TRPD_MYCTU
A:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
SS-
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------
16
PsiBlast_PDB
78.91
32%
-69
- C13 -
4N93
6
TRPD_MYCTU
A:
[102-356]
-----------------------------------------------------------------------------
A
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
-
I
D
-
L
-
G
P
D
L
V
A
R
S
-
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
--
A
D
L
A
E
V
M
A
G
V
F
A
A
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
-
G
S
V
D
K
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
A
A
A
V
R
A
V
L
G
G
A
-
R
G
P
V
R
---------
D
A
V
V
L
N
A
A
G
A
I
V
A
H
A
G
L
SS-
A
E
W
L
P
--
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
-------------