@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0063: (2015-12-12 )
MVKIGVCGPVGSGKTALIEALTRHMSKDYDMAVITNDIYTKEDAEFMCKNSVMPRDRIIGVETGGCPHTAIREDASMNLEAVEEMHGRFPNLELLLIESGGDNLSATFNPELADFTIFVIDVAEGDKIPRKGGPGITRSDLLVINKIDLAPYVGADLKVMERDSKKMRGEKPFIFTNIRAKEGLDDVIAWIKRNALLED
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20......-.-.30---.........40........50..---......60.----..-.....70..----.....-----.80....--...--.--90-.........100...-----.----...110..-..-...120.......130---..-.--.....-.-140.......150..--.--....160..-...-----.-----.170------........180.......190.......----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
K
I
G
V
CGPVGS
G
K
T
A
L
I
E
A
L
T
R
H
MSK-D-Y
D
----
M
A
V
I
TNDIYTKE
D
A
E
F
M
CKNSVM---PRD
R
I
I
G
V
E----TG-GCP
H
T
A
IRE----DASM
N
-----
L
E
A
V
E
E
M
--HGR--F--P--N
L
E
L
L
L
IESGGDN
L
S
-----
A
----TFNPELA
D
-
F
T
-
I
F
V
I
DVAEGDKIPR-----KG-G--PGITR-S-
D
L
L
V
I
N
KIDLAPYVG--A--D
L
K
V
M
ER
D
S
-
K
KM-----R-----GEK-------
P
F
I
F
T
NIRAKE
G
L
D
D
V
I
A
W
I
K
R
NALLED----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
98.65
99%
-112
- C3 -
4HI0
2
UREG_HELPY
E:
[1-196]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
K
I
G
V
C
G
P
V
G
S
G
K
T
A
L
I
E
A
L
T
R
H
M
S
K
-
D
-
Y
D
----
M
A
V
I
T
N
D
I
Y
T
K
E
D
A
E
F
M
C
K
N
S
V
M
---
P
R
E
R
I
I
G
V
E
----
T
G
-
G
C
P
H
T
A
I
R
E
----
D
A
S
M
N
-----
L
E
A
V
E
E
M
--
H
G
R
--
F
--
P
--
N
L
E
L
L
L
I
E
S
G
G
D
N
L
S
-----
A
----
T
F
N
P
E
L
A
D
-
F
T
-
I
F
V
I
D
V
A
E
G
D
K
I
P
R
-----
K
G
-
G
--
P
G
I
T
R
-
S
-
D
L
L
V
I
N
K
I
D
L
A
P
Y
V
G
--
A
--
D
L
K
V
M
E
R
D
S
-
K
K
M
-----
R
-----
G
E
K
-------
P
F
I
F
T
N
I
R
A
K
E
G
L
D
D
V
I
A
W
I
K
R
N
A
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
98.58
99%
-112
- C3 -
4HI0
2
UREG_HELPY
F:
[1-196]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
K
I
G
V
C
G
P
V
G
S
G
K
T
A
L
I
E
A
L
T
R
H
M
S
K
-
D
-
Y
D
----
M
A
V
I
T
N
D
I
Y
T
K
E
D
A
E
F
M
C
K
N
S
V
M
---
P
R
E
R
I
I
G
V
E
----
T
G
-
G
C
P
H
T
A
I
R
E
----
D
A
S
M
N
-----
L
E
A
V
E
E
M
--
H
G
R
--
F
--
P
--
N
L
E
L
L
L
I
E
S
G
G
D
N
L
S
-----
A
----
T
F
N
P
E
L
A
D
-
F
T
-
I
F
V
I
D
V
A
E
G
D
K
I
P
R
-----
K
G
-
G
--
P
G
I
T
R
-
S
-
D
L
L
V
I
N
K
I
D
L
A
P
Y
V
G
--
A
--
D
L
K
V
M
E
R
D
S
-
K
K
M
-----
R
-----
G
E
K
-------
P
F
I
F
T
N
I
R
A
K
E
G
L
D
D
V
I
A
W
I
K
R
N
A
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
103
Fugue
67.61
33%
-82
* C3 *
2HF9
4
HYPB_METJA
A:
[16-226]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------KD
I
L
K
A
N
K
R
L
A
D
K
N
R
K
L
L
N
K
H
G
V
V
A
F
D
F
M
G
A
I
G
S
G
K
T
L
L
I
E
K
L
I
D
N
L
K
D
-
K
-
Y
K
----
I
A
C
I
A
G
D
V
I
A
K
F
D
A
E
R
M
E
K
H
G
A
-------
K
V
V
P
L
N
----
T
G
-
K
E
C
H
L
--------
D
A
H
L
V
-----
G
H
A
L
E
D
L
----
N
--
L
--
D
--
E
I
D
L
L
F
I
E
N
V
G
N
L
I
C
-----
P
----
A
D
F
D
L
G
T
H
-
K
R
-
I
V
V
I
S
T
T
E
G
D
D
T
I
E
-----
K
H
-
P
--
G
I
M
K
T
-
A
-
D
L
I
V
I
N
K
I
D
L
A
D
A
V
G
--
A
--
D
I
K
K
M
E
N
D
A
-
K
R
I
-----
N
-----
P
D
A
-------
E
V
V
L
L
S
L
K
T
M
E
G
F
D
K
V
L
E
F
I
E
K
S
V
K
E
V
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
112
HHSearch
64.93
33%
-77
- C3 -
2HF9
4
HYPB_METJA
A:
[38-225]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
A
F
D
F
M
G
A
I
G
S
G
K
T
L
L
I
E
K
L
I
D
N
L
K
D
-
K
-
Y
K
----
I
A
C
I
A
G
D
V
I
A
K
F
D
A
E
R
M
E
K
H
G
-------
A
K
V
V
P
L
N
----
T
G
-
K
E
C
H
L
D
--
A
----
H
L
-
V
------
G
H
A
L
E
D
L
---
N
---
L
--
D
--
E
I
D
L
L
F
I
E
N
V
G
N
L
I
C
-----
P
----
A
D
F
D
L
G
T
H
-
K
R
-
I
V
V
I
S
T
T
E
G
D
D
T
I
E
-----
K
H
-
P
--
G
I
M
K
T
-
A
-
D
L
I
V
I
N
K
I
D
L
A
D
A
V
G
--
A
--
D
I
K
K
M
E
N
D
A
-
K
R
I
-----
N
-----
P
D
A
-------
E
V
V
L
L
S
L
K
T
M
E
G
F
D
K
V
L
E
F
I
E
K
S
V
K
E
V
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
102
Fugue
64.76
25%
-88
- C3 -
2WSM
1
?
A:
[11-213]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------L
A
E
N
K
R
L
A
E
K
N
R
E
A
L
R
E
S
G
T
V
A
V
N
I
M
G
A
I
G
S
G
K
T
L
L
I
E
R
T
I
E
R
I
G
N
-
E
-
V
K
----
I
G
A
M
L
G
D
V
V
S
K
A
D
Y
E
R
V
R
R
F
G
I
-------
K
A
E
A
I
S
----
T
G
-
K
E
C
H
------------
L
D
-----
A
H
M
I
Y
H
R
--
L
K
K
--
F
--
S
--
D
C
D
L
L
L
I
E
N
V
G
N
L
I
C
-----
P
----
V
D
F
D
L
G
E
N
-
Y
R
-
V
V
M
V
S
V
T
E
G
D
D
V
V
E
-----
K
H
-
P
--
E
I
F
R
V
-
A
-
D
L
I
V
I
N
K
V
A
L
A
E
A
V
G
--
A
--
D
V
E
K
M
K
A
D
A
-
K
L
I
-----
N
-----
P
R
A
-------
K
I
I
E
M
D
L
K
T
G
K
G
F
E
E
W
I
D
F
L
R
G
I
L
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
63.85
36%
-80
- C3 -
2HF9
5
HYPB_METJA
B:
[45-221]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
I
G
S
G
K
T
L
L
I
E
K
L
I
D
N
L
K
D
-
K
-
Y
K
----
I
A
C
I
A
G
D
V
I
A
K
F
D
A
E
R
M
E
K
H
G
A
-------
K
V
V
P
L
N
----
T
G
-
K
E
C
H
L
--------
D
A
H
L
V
-----
G
H
A
L
E
D
L
--
N
----
L
--
D
--
E
I
D
L
L
F
I
E
N
V
G
-
N
L
I
-----
C
----
P
A
D
F
D
L
G
T
-
H
K
R
I
V
V
I
S
T
T
E
G
D
D
T
I
E
-----
K
H
----
P
G
I
M
K
-
T
A
D
L
I
V
I
N
K
I
D
L
A
D
A
V
G
--
A
--
D
I
K
K
M
E
N
D
A
-
K
R
I
-----
N
-----
P
D
A
-------
E
V
V
L
L
S
L
K
T
M
E
G
F
D
K
V
L
E
F
I
E
K
S
V
K
E
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
62.73
35%
-79
- C3 -
2HF8
5
HYPB_METJA
A:
[45-221]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
I
G
S
G
K
T
L
L
I
E
K
L
I
D
N
L
K
D
-
K
-
Y
K
----
I
A
C
I
A
G
D
V
I
A
K
F
D
A
E
R
M
E
K
H
G
A
-------
K
V
V
P
L
N
----
T
G
-
K
E
C
H
L
--------
D
A
H
L
V
-----
G
H
A
L
E
D
L
--
N
----
L
--
D
--
E
I
D
L
L
F
I
E
N
V
G
-
N
L
I
-----
C
----
P
A
D
F
D
L
G
T
-
H
K
R
I
V
V
I
S
T
T
E
G
D
D
T
I
E
-----
K
H
----
P
G
I
M
K
-
T
A
D
L
I
V
I
N
K
I
D
L
A
D
A
V
G
--
A
--
D
I
K
K
M
E
N
D
A
-
K
R
I
-----
N
-----
P
D
A
-------
E
V
V
L
L
S
L
K
T
M
E
G
F
D
K
V
L
E
F
I
E
K
S
V
K
E
V
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
62.27
36%
-82
- C3 -
2HF9
4
HYPB_METJA
A:
[45-221]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
I
G
S
G
K
T
L
L
I
E
K
L
I
D
N
L
K
D
-
K
-
Y
K
----
I
A
C
I
A
G
D
V
I
A
K
F
D
A
E
R
M
E
K
H
G
A
-------
K
V
V
P
L
N
----
T
G
-
K
E
C
H
L
--------
D
A
H
L
V
-----
G
H
A
L
E
D
L
--
N
----
L
--
D
--
E
I
D
L
L
F
I
E
N
V
G
-
N
L
I
-----
C
----
P
A
D
F
D
L
G
T
-
H
K
R
I
V
V
I
S
T
T
E
G
D
D
T
I
E
-----
K
H
----
P
G
I
M
K
-
T
A
D
L
I
V
I
N
K
I
D
L
A
D
A
V
G
--
A
--
D
I
K
K
M
E
N
D
A
-
K
R
I
-----
N
-----
P
D
A
-------
E
V
V
L
L
S
L
K
T
M
E
G
F
D
K
V
L
E
F
I
E
K
S
V
K
E
V
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
61.04
29%
-86
- C3 -
2WSM
1
?
A:
[31-209]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
V
N
I
M
G
A
I
G
S
G
K
T
L
L
I
E
R
T
I
E
R
I
G
N
-
E
-
V
K
----
I
G
A
M
L
G
D
V
V
S
K
A
D
Y
E
R
V
R
R
F
G
I
K
---
A
E
----
A
I
S
----
T
G
-
K
E
C
H
L
--------
D
A
H
M
I
-----
Y
H
R
L
K
------
K
--
F
--
S
--
D
C
D
L
L
L
I
E
N
V
G
-
N
L
I
-----
C
----
P
V
D
F
D
L
G
E
N
Y
R
-
V
V
M
V
S
V
T
E
G
D
D
V
V
E
-----
K
H
----
P
E
I
F
R
V
A
-
D
L
I
V
I
N
K
V
A
L
A
E
A
V
G
--
A
--
D
V
E
K
M
K
A
D
A
-
K
L
I
-----
N
-----
P
R
A
-------
K
I
I
E
M
D
L
K
T
G
K
G
F
E
E
W
I
D
F
L
R
G
I
L
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
113
HHSearch
60.81
25%
-78
- C3 -
2WSM
1
?
A:
[30-213]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
A
V
N
I
M
G
A
I
G
S
G
K
T
L
L
I
E
R
T
I
E
R
I
G
N
-
E
-
V
K
----
I
G
A
M
L
G
D
V
V
S
K
A
D
Y
E
R
V
R
R
F
G
---------
I
K
A
E
A
----
I
S
T
G
K
E
C
H
L
-----------
D
-----
A
H
M
I
Y
H
R
--
L
K
K
--
F
--
S
--
D
C
D
L
L
L
I
E
N
V
G
N
L
I
C
-----
P
----
V
D
F
D
L
G
E
N
-
Y
R
-
V
V
M
V
S
V
T
E
G
D
D
V
V
E
-----
K
H
-
P
--
E
I
F
R
V
-
A
-
D
L
I
V
I
N
K
V
A
L
A
E
A
V
G
--
A
--
D
V
E
K
M
K
A
D
A
-
K
L
I
-----
N
-----
P
R
A
-------
K
I
I
E
M
D
L
K
T
G
K
G
F
E
E
W
I
D
F
L
R
G
I
L
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
116
HHSearch
57.42
19%
-94
- C3 -
2WWW
2
MMAA_HUMAN
A:
[75-279]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
V
G
L
S
G
P
P
G
A
G
K
S
T
F
I
E
Y
F
G
K
M
L
T
E
R
G
-
H
K
----
L
S
V
L
A
V
D
P
-------------------------
T
E
LSRD
M
N
-
A
Y
I
R
P
S
-----------------
T
R
T
T
N
E
A
--
I
L
L
C
E
G
--
A
--
G
Y
D
I
I
L
I
E
T
V
G
V
--
S
-----
E
----
F
A
V
A
D
M
V
D
-
M
F
-
V
L
L
L
P
P
A
--------------------
I
E
M
-
A
-
D
L
V
A
V
T
K
S
D
G
D
L
I
V
P
A
R
R
--
I
Q
A
E
Y
V
S
A
L
-
K
L
L
R----------
W
K
P
-------
K
V
I
R
I
S
A
R
S
G
E
G
I
S
E
M
W
D
K
M
K
D
F
Q
D
L
M
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
124
HHSearch
55.33
21%
-61
- C3 -
3E70
3
?
C:
[130-318]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
H
G
-
F
S
----
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
R
---
I
G
V
K
V
I
K
H
S
----
Y
G
-
A
D
P
--------------------
A
A
V
A
Y
D
A
--
I
Q
H
--
A
KA
R
--
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
NRNLM
D
EMKK
I
A
R
V
T
K
P
N
-
L
V
-
I
F
V
G
D
A
L
A
G
N
A
I
V
E
-----
Q
A
-
R
QF
N
E
A
V
K
-
I
-
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
--
A
--
A
L
S
I
----
S
-
Y
-------
V
-----
I
D
A
-------
P
I
L
F
V
G
--
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
120
HHSearch
54.18
17%
-75
- C3 -
3P32
3
Y1496_MYCTU
A:
[80-283]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
R
V
G
I
T
G
V
P
G
V
G
K
S
T
A
I
E
A
L
G
M
H
L
I
E
R
G
-
H
R
----
V
A
V
L
A
V
D
---------------
M
---
A
---
R
L
A
V
H
----
P
N
-
A
Y
I
R
P
S
P
--GT
L
G
G
V
T
R
A
-----
T
R
E
T
V
V
L
--
L
E
---
A
--
A
--
G
F
D
V
I
L
I
E
T
V
G
V
G
Q
S
-----
E
----
V
A
V
A
N
M
V
D
-
T
F
-
V
L
L
T
L
A
R
T
G
D
Q
L
Q
G
-----
I
K
-
K
--
G
V
L
E
L
-
A
-
D
I
V
V
V
N
K
A
D
G
E
H
H
K
E
--
A
R
L
A
A
R
E
L
S
A
A
I
-
R
L
I
-----
Y
PREAL
W
R
P
-------
P
V
L
T
M
S
A
V
E
G
R
G
L
A
E
L
W
D
T
V
E
R
H
R
Q
V
L
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
129
HHSearch
52.87
22%
-65
- C3 -
3GEH
3
MNME_NOSS1
A:
[225-383]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
V
A
I
V
G
R
P
N
V
G
K
S
S
L
L
N
A
W
S
Q
S
D
R
-----------
A
I
V
T
D
L
P
G
T
T
R
D
V
V
E
--
S
Q
L
V
V
---
G
G
I
P
V
Q
V
L
D
----------------------------------------------------------------------------
Q
A
A
N
T
A
D
-
L
V
-
L
L
T
I
D
A
A
T
G
W
T
T
G
D
Q
----
E
I
Y
E
--
Q
V
K
H
R
-
P
-
L
I
L
V
M
N
K
I
D
L
V
E
K
Q
L
--
I
----
T
S
----
L
-
E
Y
P
-----
E
-----
N
I
T
-------
Q
I
V
H
T
A
A
A
Q
K
Q
G
I
D
S
L
E
T
A
I
L
E
I
V
Q
T
G
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
117
HHSearch
52.08
19%
-63
- C3 -
1MKY
3
DER_THEMA
A:
[181-355]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
K
V
A
I
V
G
R
P
N
V
G
K
S
T
L
F
N
A
I
L
N
K
E
R
A
-----------
L
V
S
P
I
P
------
V
D
D
--
E
V
F
I
---
D
G
R
K
Y
V
F
V
D
----
T
A
-
G
L
-------------------------
E
K
Y
--
S
N
Y
----------------------
R
-----
V
----
V
D
S
I
E
K
A
D
-
V
V
-
V
I
V
L
D
A
T
Q
G
I
T
R
Q
D
Q
R
M
A
-
G
L
-
M
--
E
R
R
G
R
-
A
-
S
V
V
V
F
N
K
W
D
L
V
V
H
R
E
--
K
--
R
Y
D
E
F
T
K
L
F
-
R
E
K
L
YF--
I
-----
D
Y
S
-------
P
L
I
F
T
S
A
D
K
G
W
N
I
D
R
M
I
D
A
M
N
L
A
Y
A
S
Y
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
114
HHSearch
51.69
20%
-66
- C3 -
3IEV
2
ERA_AQUAE
A:
[11-182]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
Y
V
A
I
V
G
K
P
N
V
G
K
S
T
L
L
N
N
L
L
G
T
K
-----------
V
S
I
I
S
P
K
A
G
T
T
R
M
R
V
L
----
G
V
K
N
I
P
N
E
A
Q
I
I
F
L
D
----
T
P
-
G
I
Y
E
P
K
K
S
D
----------------
V
L
G
H
S
--
M
V
E
--
I
-------------------------
A
----
K
Q
S
L
E
E
A
D
-
V
I
-
L
F
M
I
D
A
T
E
G
W
R
P
R
D
E
E
I
Y
Q
N
F
-
I
--
K
P
L
N
K
-
P
-
V
I
V
V
I
N
K
I
D
K
I
G
P
A
K
--
N
---
V
L
P
L
I
D
E
I
H
K
K
H
-----
P
-----
E
L
T
-------
E
I
V
P
I
S
A
L
K
G
A
N
L
D
E
L
V
K
T
I
L
K
Y
L
P
E
G
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
104
Fugue
51.50
19%
-75
- C3 -
2P67
5
ARGK_ECOLI
A:
[2-329]
-------------------------------------------------------------------------------------------------------------------------------------SLINEAT
L
A
E
S
I
R
R
L
R
Q
GE
R
A
T
L
A
Q
A
M
T
L
V
E
SRH
P
R
H
Q
A
L
S
T
Q
L
L
D
A
I
MPYCGN
T
L
R
L
G
V
T
G
T
P
G
A
G
K
S
T
F
L
E
A
F
G
M
L
L
I
R
-
E
G
L
K
----
V
A
V
I
A
V
D
-----------
P
S
N
D
L
---
A
R
A
E
A
A
F
I
R
----
P
V
-
P
S
G
A
S
Q
R
A
R
----
E
L
M
L
L
-----
C
E
A
A
----------------
G
Y
D
V
V
I
V
E
T
V
G
V
G
Q
S
-----
E
----
T
E
V
A
R
M
V
D
-
C
F
-
I
S
L
Q
I
-------
A
Q
-----
G
I
-
K
--
K
G
L
M
E
V
A
-
D
L
I
V
I
N
K
D
D
G
D
N
H
T
N
--
V
--
A
I
A
R
H
M
Y
E
S
-
A
L
H
-----
I
-----
L
R
R
KYDEWQ
P
R
V
L
T
C
S
A
L
E
K
R
G
I
D
E
I
W
H
A
I
I
D
F
K
T
A
L
T
A
S
G
R
L
Q
Q
V
R
Q
Q
Q
S
V
E
W
L
R
K
Q
T
E
E
E
V
L
N
H
L
F
A
N
E
D
F
D
R
Y
Y
R
Q
T
L
L
A
V
K
N
NTLS
P
R
T
G
L
R
Q
L
S
E
F
I
Q
T----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
105
Fugue
50.38
20%
-59
- C3 -
4XC8
4
?
A:
[42-1113]
GPANK
V
R
F
V
T
A
A
S
L
FDGHDAS
I
N
I
M
R
R
I
L
Q
S
Q
GCEVIHLGHNRS
V
Q
E
V
V
T
A
A
L
Q
E
DVQ
G
I
A
I
S
S
YQGG
H
V
E
Y
F
K
Y
M
I
D
L
L
R
E
H
GGEH
I
Q
V
F
G
G
GGGVIV
P
D
E
I
R
E
L
Q
A
Y
GVA
R
I
Y
S
P
E
D
G
Q
R
MG
L
A
G
M
I
T
D
M
A
Q
R
C
DIDLTRYAPTTL
D
T
V
V
A
GD
R
R
A
L
A
Q
L
I
T
A
L
E
N
GKAD
P
E
L
V
S
A
L
H
A
Q
A
K
A
A
A
V
P
V
L
G
I
T
G
T
G
G
A
G
K
S
S
L
T
D
E
L
I
R
R
F
R
L
-
D
-
Q
D
DA
L
S
I
A
V
I
S
I
D
P
S
R
R
K
S
------
G
G
A
L
---
L
G
D
R
I
R
-
M
N
----
A
I
-
N
H
P
N
I
F
M
R
S
----
L
A
T
R
E
AGSEI
S
Q
A
L
P
D
V
--
I
A
A
--
C
--
K
A
A
R
F
D
L
V
I
V
E
T
S
G
I
G
Q
G
-----
D
----
A
A
I
V
P
H
V
D
-
L
S
-
L
Y
V
M
T
P
E
F
G
A
A
S
Q
L
-----
E
K
-
I
--
D
M
L
D
F
-
A
-
D
F
V
A
I
N
K
F
D
R
K
G
A
Q
D
--
A
--
W
R
D
V
A
K
Q
V
Q
-
R
N
R
EQWHS
R
-----
A
E
D
-------
M
P
V
Y
G
T
-
Q
A
S
R
F
N
D
D
G
V
T
M
L
Y
Q
G
L
V
G
A
L
G
A
RG
M
S
L
K
PGTLPNLEGRISTGQNVIVPPARSR
Y
L
A
E
L
A
D
T
V
R
A
Y
H
R
R
V
V
A
Q
S
K
L
A
R
E
R
Q
Q
L
R
A
A
H
D
M
L
Q
G
A
GHESA
A
L
E
T
L
A
S
E
R
D
V
S
LG
A
V
E
R
K
L
L
A
M
W
P
Q
M
Q
Q
A
Y
S
GDEYVE
I
R
T
G
L
I
S
T
T
LSG
T
K
I
R
K
V
V
L
P
RFED
E
G
E
I
L
K
W
L
M
R
ENVPGSFPYTAGVFAFKREGEDP
T
R
M
F
A
G
E
G
D
A
F
R
T
N
R
R
F
K
L
V
S
EGMEAK
R
L
S
T
A
F
D
S
V
T
L
Y
GEDPHERPDIYGKVGNS
G
V
S
I
A
T
L
E
D
M
K
V
L
Y
DGFDLTNPS
T
S
V
S
M
T
I
N
GP
A
P
T
I
L
A
M
F
M
N
T
A
I
D
Q
Q
I
D
R
F
R
A
D
N
GRDPT
A
D
E
E
A
K
I
R
A
W
V
L
Q
N
V
R
G
T
V
QAD
I
L
K
E
D
Q
GQNTCIFS
T
E
F
S
L
K
V
M
G
D
I
Q
E
Y
F
V
H
H
QVRNFYSVSISG
Y
H
I
A
E
A
GAN
P
I
S
Q
L
A
F
T
L
A
N
G
F
T
Y
V
E
A
Y
L
A
R
GMHIDDFAPN
L
S
F
F
F
S
N
G
MD
P
E
Y
S
V
L
G
R
V
A
R
R
I
W
A
V
T
M
R
DKYGANDRSQ
K
L
K
Y
H
I
Q
T
S
GRSLHAQEIDF
N
D
I
R
T
T
L
Q
A
L
I
A
I
Y
D
NCN
S
L
H
T
N
A
YDEAITTPT
A
E
S
V
R
R
A
L
A
I
Q
L
I
I
N
REWGVAKCENPNQGS
F
L
I
E
E
L
T
D
L
V
E
E
A
V
L
Q
E
F
E
R
I
A
E
R
GG
V
L
G
A
M
E
T
G
Y
Q
R
G
K
I
Q
E
E
S
L
Y
Y
E
Q
L
K
H
D
GTLPIIGVNTFRNPNGDPRSS
E
D
E
K
Q
S
Q
L
H
R
L
T
E
F
H
G
A
H
QAD
A
E
A
M
L
A
R
L
R
Q
A
V
I
D
NRN
V
F
A
V
L
M
D
A
V
R
V
CS
L
G
Q
I
T
H
A
L
F
E
V
GGQYRRNM
5
PsiBlast_PDB
49.09
25%
-51
- C3 -
4LPS
12
HYPB_HELPY
A:
[56-230]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
G
K
T
T
M
L
E
N
L
A
D
F
--
K
-
D
-
F
K
----
F
C
V
V
E
G
D
L
Q
T
N
R
D
A
D
R
L
R
K
K
G
V
S
---
A
H
Q
----
I
T
----
T
G
-
E
A
C
H
L
--------
E
A
S
M
I
-----
E
G
A
F
D
L
L
K
D
E
G
A
--
L
--
E
--
K
S
D
F
L
I
I
E
N
V
G
N
L
V
C
-----
P
----
S
S
Y
N
L
G
A
A
-
M
N
-
I
V
L
L
S
V
P
E
G
D
D
K
V
L
-----
K
Y
-
P
--
T
M
F
M
C
-
A
-
D
A
V
I
I
S
K
A
D
M
V
E
V
F
N
--
F
--
R
V
S
Q
V
K
E
D
M
-
Q
K
L
-----
K
-----
P
E
A
-------
P
I
F
L
M
S
S
K
D
P
K
S
L
E
D
F
-----
K
N
F
L
L
E
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
110
Fugue
48.34
16%
-94
- C3 -
4NKR
3
?
B:
[1-166]
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F
P
I
V
Q
V
V
G
F
Q
N
S
G
K
T
T
F
I
E
R
I
L
E
K
A
S
E
-
Q
G
L
N
----
L
G
C
L
K
H
H
D
R
Y
Q
A
A
--------------
G
A
D
V
T
A
V
E
----
G
A
-
G
--
V
L
Q
L
T
A
----
R
R
L
W
D
-----
L
T
R
L
I
E
L
--
Y
Q
F
--
L
-----
E
T
D
C
L
L
I
E
G
F
K
K
A
P
Y
-----
P
--------------
K
-
V
V
I
L
S
E
K
E
D
L
E
A
L
K
-----
T
--------
V
N
-
T
-
I
A
I
I
Y
R
K
---------------------
K
-
E
H
M
-----
T
-----
E
H
Q
-------
G
L
P
I
F
H
A
D
D
P
V
A
V
D
L
V
L
S
Q
L
K
G
E
S
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