@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0250: (2015-12-13 )
MFDNTLINLFETAPLLTSLLAGILTFLSPCVLPLIPAYMSYISQISLEDIKDGKAKRVSVFLKSLMFVVGFSLVFLGVGMSMAKLIHSFSFSWVNYIAGGIVILFGLHFLGVFRFAFLYKTQSVGLASKSNSMQRFYPFLLGMSFALGWTPCIGPIFTSIVIMSASKDAYGLMLMVVFVMGLAIPFLLVALMLERALLFLKSLRKYNRAIEIVSGLVLILMGILIMTNSLESLTNFLQN
Atome Classification :
(13 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------..-.......10-----....-.....20.-...-....30....--------....----40....-..--------..50.--....-...60........70---..-------------...-...80----------...-.....90..------.....-.100.......110-------.----....----..-..120......---.130........-.140----.-..----......150---------..--......160....--....170.--......180.....---..190...-----..-----..200------..-...-....210..--------...-----..--220...----....230.......---------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MF-D
N
T
L
I
N
L
F
------
E
T
A
P
-
L
L
T
S
L
L
A
G
-
I
L
T
-
F
L
S
P
C
V
L
P
L
I
--------
P
A
Y
M
----
S
Y
I
S
QI-
S
L
--------
E
D
IKD--GK
A
K
-
R
V
S
V
F
L
K
S
L
M
F
V
V
G
F
---
S
L
-------------
V
F
L
-GV
G
M
S
----------
M
A
K
-
L
I
H
S
F
S
F
S
W
------
V
N
Y
IA-
G
G
I
V
I
L
F
G
L
H
F
L
---------
G
----
V
F
R
F
----
A
F
-
L
YKTQSVGLAS---KS--N
S
M
Q
R
F
Y
P
-
F
L
------
L
-
G
M
----
S
FALGWTP----------
C
I
--
G
P
I
F
T
S
I
-
V
I
M
SA--SKD
A
Y
G
L
M
--
L
M
V
V
F
V
M
G
L
A
I
P
F
L
---
L
V
A
L
M
L
E
R
-----
A
L
-----
L
F
L
--------
K
S
-
L
R
K
-
Y
N
R
A
I
E
I
V
S
--------
G
L
V
-----
L
I
--
L
M
G
I
L
I
----MTN
S
L
E
S
L
T
N
F
LQN---------------------------------------------------------------------------------
16
Fugue
89.76
15%
-168
- C4 -
2YXO
5
?
A:
[1-263]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
-
D
S
H
V
H
T
P
L
CGHAEG
H
P
E
A
-
Y
L
E
E
A
R
A
K
-
G
L
K
-
G
V
V
F
T
D
H
S
P
M
--------
P
P
W
Y
----
D
P
E
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R
M
-
R
L
--------
E
A
L
P
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L
L
A
L
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-
R
V
R
E
R
A
Q
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L
Y
V
G
I
G
L
---
E
A
-------------
D
F
H
P
G
T
E
G
F
----------
L
A
Q
-
L
L
R
R
Y
P
F
D
Y
----------------
V
I
G
S
V
H
Y
L
---------
G
----
A
W
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----
D
H
-
P
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E
E
Y
A
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---
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--
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F
R
A
Y
F
Q
-
E
V
------
E
-
K
A
A
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SG
L
F
H
A
I
G
H
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----------
D
L
--
P
K
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F
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-
L
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E
A
--
L
L
E
L
A
E
P
A
--
L
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A
V
A
E
A
G
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F
L
D
V
N
---
T
A
G
L
R
R
P
A
KEVYP
A
P
-----
A
L
L
--------
R
R
-
A
R
E
-
L
G
I
G
L
V
L
G
S
DAHRPEEV
G
F
A
-----
F
P
--
E
V
Q
A
L
L
----
A
G
L
G
F
R
E
A
Y
Y
F
V
E
G
S
P
V
A
Y
P
L--------------------------------------------------------------------------
11
Fugue
88.06
21%
-149
- C5 -
3VWA
-
CEX1_YEAST
A:
[1-540]
PLHMSISNFQFP
Y
T
I
E
ETAITETAL
W
Q
C
F
D
G
T
R
K
ADSL
P
V
T
V
F
K
A
KRSPEN
E
S
L
I
L
N
A
V
H
K
S
K
I
LKIPGLCTVL
E
T
F
D
SDPQS
T
F
I
V
T
E
R
V
V
P
FPWDN
L
G
S
L
S
Q
N
K
F
G
V
E
L
G
I
S
Q
L
L
A
T
L
G
F
L
K
NFVLGTLSKDS
V
F
I
N
IKG
E
W
V
L
F
G
LELCSSKEGLS
A
F
E
F
A
S
R
A
R
S
Y
Y
N
I
I
GSQLPCEDPNT
I
D
S
M
G
L
G
L
L
I
K
S
L
M
APSCLPKDW
I
V
N
V
N
M
I
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D
GKIT
I
E
N
F
R
K
R
L
E
N
T
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T
W
R
S
N
P
L
I
N
F
Y
Q
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L
R
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LHIKD
P
Q
G
K
L
V
V
M
S
N
L
E
N
L
Y
L
------
E
S
R
E
-
I
F
R
N
L
T
P
G
M
I
E
N
-
F
-------
I
I
--------
P
E
L
C
----
E
I
I
K
L
L
M
T
---------
Q
S
I
S
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--
N
A
S
H
-
K
L
V
P
F
L
A
I
V
L
D
L
T
S
E
---
T
---------------------------------------
N
T
F
P
V
G
F
------
N
D
L
I
T
-
Q
S
F
K
----
L
P
D
R
---------
Q
----
V
R
F
L
----
L
L
-
I
Y
L
P
K
L
I
G
P
L
S
---
K
S
--
E
I
S
S
R
I
Y
P
H
F
I
------
Q
-
G
L
----
T
--------------------------------------
D
S
D
A
T
L
--
R
L
Q
T
L
K
T
I
P
C
I
V
S
C
---
L
T
E
R
Q
L
N
N
-----
E
L
-----
L
R
F
--------
L
A
-
K
T
Q
-
V
D
S
D
V
E
I
R
T
--------
W
T
V
-----
I
I
--
I
S
K
I
S
T
I---
L
S
T
S
V
G
N
R
S
N
I
L
A
T
A
F
T
K
S
L
K
DPQ
V
K
P
R
L
A
A
L
Y
G
L
E
K
S
I
ELFD
V
N
T
I
A
N
K
I
L
T
V
I
APGLLDKS
P
I
V
R
G
R
A
K
I
L
F
E
E
Y
L
E
K
L
E
K
E
A
Q
L
IQTN----
9
Fugue
83.19
15%
-181
- C5 -
3ZPJ
-
?
A:
[1-356]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
T
T
L
E
E
I
N
L
L
V
E
R
G
Y
Y
-
E
E
A
L
A
K
V
Y
EIED
P
I
E
Q
V
Q
-
V
L
T
K
I
V
V
T
-
I
Y
Q
-
H
D
G
P
--
M
E
W
I
--------
P
S
I
M
----
E
D
A
M
Y
I
-
A
K
--------
K
L
R
D
P
--
A
N
K
A
-
V
A
Y
S
I
I
A
S
T
L
A
I
M
E
Y
E
E
D
A
M
-------------
D
F
F
-
N
R
A
I
D
----------
E
A
N
-
E
I
E
S
------------
P
I
E
K
-
G
M
V
L
S
T
L
A
Y
H
L
A
I
A
GY
P
D
N
A
L
E
----
I
F
N
I
----
A
F
D
T
I
I
G
A
E
T
S
Y
T
H
---
K
V
--
D
G
I
L
R
I
G
D
-
L
L
E
K
A
G
D
T
L
-
P
S
----
N
E
A
M
D
F
Y
K
----------
M
A
--
F
D
I
F
D
K
L
-
H
V
N
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R
--
A
A
I
V
E
K
K
I
--
E
L
A
K
T
V
Y
D
V
G
L
P
Q
I
---
R
A
A
L
L
K
G
K
-----
N
H
-----
Y
A
L
--------
A
I
-
I
K
K
K
Y
S
G
V
M
R
L
I
G
--------
E
L
E
-----
V
A
--
L
W
M
K
R
V
NNME
Y
L
D
V
V
D
K
A
F
E
C
C
E
S
PRFT
D
V
N
V
Q
H
I
A
R
L
L
T
E
L
GN
L
R
R
A
L
K
F
A
K
E
IQN
I
H
K
R
S
E
A
L
K
A
I
A
L
E
L
V
R
R
KKFEE
V
K
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I
I
E
S
IPD
P
K
I
R
E
E
A
L
N
E
I
GTIE
15
Fugue
65.12
8%
-161
* C5 *
3U64
4
Y956_TREPA
A:
[30-300]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D
F
T
R
V
F
T
E
-
E
D
D
L
D
L
V
A
------
Q
S
L
P
-
L
V
L
K
V
Y
E
A
-
L
H
L
-
Q
N
P
A
H
R
G
L
S
L
--------
A
V
G
R
----
L
Y
I
M
Y
A
-
N
A
FV
Q
T
P
A
Q
Y
L
P
E
D
E
--
F
E
A
Q
-
N
E
A
Y
S
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A
R
K
L
Y
L
R
G
A
---
R
Y
-------------
A
L
S
-
S
L
E
T
A
----------
Y
P
G
-
F
T
R
E
V
F
S
G
D
------
E
Q
R
L
H
-
K
V
L
S
R
C
T
R
V
D
V
G
---------
T
----
L
Y
W
V
----
G
T
-
G
Y
V
A
A
F
A
L
T
P
L
---
G
S
--
A
L
P
D
T
V
H
A
-
A
V
------
M
-
M
L
----
E
R
A
C
D
L
W
P
----------
S
Y
QE
G
A
V
W
N
V
L
-
T
K
F
Y
A
A
A
P
E
S
F
G
G
G
M
--
E
K
A
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T
A
F
E
H
L
T
R
Y
C
SAH
D
P
D
H
H
I
T
Y
-----
A
D
-----
A
L
C
--------
I
P
-
L
N
N
-
R
A
G
F
D
E
A
L
D
--------
R
A
L
A
IDPE
S
V
--
P
H
N
K
L
L
----
V
I
L
S
Q
K
R
A
R
W
L
K
A
H
VQDFFL---------------------------------------------------------------------------
14
Fugue
60.39
13%
-150
- C2 -
3TRI
5
?
A:
[2-273]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
S
N
I
T
F
I
------
G
G
G
N
M
A
-
R
N
I
V
V
G
-
L
I
A
--------
N
G
Y
--------
D
P
N
R
----
I
C
V
T
N
R
-
S
L
--------
D
K
L
D
F
--
F
K
E
K
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G
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H
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D
N
R
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G
A
L
N
A
---
D
V
-------------
V
V
L
-
A
V
K
P
H
----------
Q
I
K
M
V
C
E
E
L
K
D
I
L
S
E
TK
I
L
V
I
S
L
A
-
V
G
V
T
T
P
L
I
E
K
W
L
---------
G
KASR
I
V
R
A
M
P
N
T
P
S
-
S
V
R
A
G
A
T
G
L
F
A
---
N
E
TV
D
K
D
Q
K
N
L
A
-
E
S
------
I
M
R
A
----
V
G
L
V
I
W
V
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S
E
--
D
Q
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E
K
I
A
-
A
L
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S
--
G
P
A
Y
I
F
L
I
M
E
A
L
Q
E
A
A
E
Q
L
G
L
T
K
E
---
T
A
E
L
L
T
E
Q
-----
T
V
-----
L
G
A
--------
A
R
M
A
L
E
-
T
E
Q
S
V
V
Q
L
R
--------
Q
F
V
-----
T
S
--
P
G
G
T
T
E
----
Q
A
I
K
V
L
E
S
G
N
L
R
E
L
F
I
K
A
L
T
A
A
V
N
R
A
K
E
L
S
K
T
VD-------------------------------------------------------------
12
Fugue
58.12
11%
-176
* C4 *
1P4N
6
FEMX_WEIVI
A:
[1-335]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVLNLND
P
Q
A
V
E
R
Y
E
E
F
M
R
Q
SPYGQVTQD
L
G
W
A
K
V
K
NN
W
E
P
V
D
V
Y
L
E
D
DQGAII
A
A
M
S
M
L
L
G
D
T
PTD
K
K
F
A
Y
A
-
S
K
G
P
V
M
D
V
------
T
D
V
D
-
L
L
D
R
L
V
D
E
-
A
V
K
-
A
L
D
G
R
A
Y
V
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F
D
P
E
V
A
Y
S
D
E
F
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----
T
T
L
Q
D
H
-
G
Y
--------
V
T
R
N
R
--
N
V
A
D
-
A
G
M
H
A
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I
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P
R
L
N
M
V
L
---
D
L
-------------
T
K
F
-
P
D
A
K
T
----------
T
L
D
-
L
Y
P
S
K
T
K
S
K
------
I
K
R
P
F
R
D
G
V
E
V
H
S
G
N
S
A
T
---------
E
----
L
D
E
F
----
F
K
-
T
Y
T
T
M
A
E
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G
I
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P
I
--
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R
M
Q
A
-
A
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------
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-
A
D
----
T
M
R
I
F
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A
E
----------
R
E
--
G
K
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L
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T
G
-
I
A
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--
G
R
K
I
W
Y
M
Y
--
A
G
S
M
D
G
N
T
Y
Y
A
P
Y
A
---
V
Q
S
E
M
I
Q
W
-----
A
L
D
T
NTD
L
Y
D
LGGIESES
T
D
-
D
S
L
-
Y
V
F
K
H
V
F
V
K
--------
D
A
P
-----
R
E
--
Y
I
G
E
I
D
----
K
V
L
D
P
E
V
Y
A
E
L
V
K
D
---------------------------------------------------------------------------------
17
Fugue
55.83
11%
-122
- C3 -
3HRQ
1
PKSL1_ASPPA
A:
[1-333]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
E
I
K
T
-
T
T
T
L
H
R
V
V
------
E
E
T
T
-
K
P
L
G
A
T
L
V
-
V
E
T
D
I
S
R
K
D
V
N
G
L
A
--------
R
G
H
L
VDG
I
P
L
C
T
P
S
-
F
Y
--------
A
D
I
A
M
--
Q
V
G
Q
-
Y
S
M
Q
R
L
R
G
L
V
D
V
S
D
M
---
V
V
D
K
ALVPHGK
G
P
Q
L
L
R
T
-
T
L
T
M
E
W
P
P
KAAATTR
S
A
K
-
V
K
F
A
T
Y
F
L
D
------
T
E
H
A
S
-
C
T
V
R
F
T
S
D
A
Q
L
K
---------
S
----
L
R
R
S
----
V
S
-
E
Y
K
T
H
I
R
Q
L
H
D
---
G
H
--
A
K
G
Q
F
M
R
Y
-
N
R
------
K
-
T
G
----
Y
K
L
M
S
S
M
A
----------
R
F
--
N
P
D
Y
M
L
L
D
Y
L
V
L
N
--
E
A
E
N
E
A
A
S
--
G
V
D
F
S
L
G
S
S
E
G
T
F
A
---
A
H
P
A
H
V
D
A
-----
I
T
-----
Q
V
A
--------
G
F
-
A
M
N
-
A
N
D
N
V
D
I
E
K
--------
Q
V
Y
-----
V
N
HG
W
D
S
F
Q
I
----
Y
Q
P
L
D
N
S
K
S
Y
Q
V
Y
T
K
MGQAND
L
V
H
G
D
V
V
V
L
DGEQIV
A
F
F
R
GL
T
L
R
S
V
P
R
G
A
L
R
V
V
L
Q
T-------------------------------------
1
PsiBlast_PDB
48.15
25%
-136
* C6 *
4C0E
-
?
A:
[200-266]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
H
R
A
F
L
P
-
V
I
------
L
-
G
L
----
P
D
E
K
G
W
A
P
F
T
K
L
L
E
Q
F
L
G
C
V
--
G
E
L
V
K
T
F
-
T
V
S
S
L
--
G
K
E
M
Y
H
A
A
--
L
K
I
L
I
V
L
Q
H
D
F
P
I
Y
---
L
D
K
F
R
V
Q
L
-----
C
Q
-----
S
L
P
--------
L
H
-
A
T
Q
-
L
V
N
L
I
L
A
A
I
--------
P
P
N
-----
C
N
--
S
L
A
D
P
F
----
Q
A
G
L
K
V
D
K
I
P
D
M
K
E
---------------------------------------------------------------------------------
2
HHSearch
28.77
36%
206
- C6 -
1V54
-
COX7C_BOVIN
L:
[26-39]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
F
F
G
S
G
F
A
A
P
F
F
---
I
V
R
H
Q
L
L
K
-----
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
27.53
39%
112
- C6 -
2Y69
-
COX7C_BOVIN
L:
[39-56]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
M
--
M
T
L
F
F
G
S
G
F
A
A
P
F
F
---
I
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
19.18
20%
98
- C7 -
2X4I
-
Y114_SIRV1
A:
[6-20]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
N
-
A
F
S
I
N
M
L
T
K
F
--------
P
T
K
V
----
V
I
D
K
I
D
-
R
L
--------
E
F
C
E
N
--
I
D
N
E
-
D
I
I
N
S
I
G
H
D
S
T
I
Q
L
I
---
N
S
-------------
L
C
G
-
T
T
F
Q
K
----------
N
R
V
-
E
I
K
L
E
K
E
D
K
------
L
Y
V
V
Q
-
I
S
I
L
T
L
E
E
I
L
K
L
---------
Y
----
E
S
G
K
----
V
Q
-
F
F
E
I
I
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
13.39
20%
218
* C7 *
2J85
-
?
A:
[6-20]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
N
-
A
F
S
I
N
M
L
K
E
F
--------
P
T
T
I
----
T
I
D
K
L
D
-
E
E
--------
D
F
C
L
K
--
L
E
L
R
-
L
E
D
G
T
L
I
N
A
I
G
H
D
S
T
---
I
N
-------------
L
V
N
-
T
L
C
G
T
----------
Q
L
Q
-
K
N
R
V
E
V
K
M
N
------
E
G
D
E
A
-
L
I
I
M
I
S
Q
R
L
E
E
G
---------
K
----
V
L
S
D
----
K
E
-
I
K
D
M
Y
R
Q
G
K
I
S
---
F
Y
--
E
V
W
H
H
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
8.80
33%
916
- C1 -
1Q68
1
?
B:
[16-24]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
C
H
Y
P
I
V
--------
P
L
D
G
----
K
G
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------