@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0637: (2015-12-17 )
MNKVITDLDKALSGLKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFGLGILLEKKQIKKIIASYVGENKIFESQMLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTPTGVGTLIAQGKESREFNGKEYILERAITGDYGLIKAYKSDTLGNLVFRKTARNFNPLCAMAAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIEKTTTRSAK
Atome Classification :
(20 SA)
......-...10........20........30........40........50........60........70........80........90........100.......110.......120.......130----------------.------------------........140.......150.......160.......170...-....180.......190.......200.......210.......220.......230---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MN
K
V
I
T
-
D
L
D
K
A
L
SGLKDG
D
T
I
L
VGGFGLCG
I
P
E
Y
A
I
D
Y
I
Y
K
KGI
K
D
L
I
V
VSNNCGVDDFG
L
G
I
L
L
E
K
K
Q
I
K
K
I
I
A
S
Y
VGENKI
F
E
S
QMLNG
E
I
E
V
V
LTPQ
G
T
L
A
E
N
L
RAGGAGIP
A
Y
YTPT
G
V
G
T
L
I
AQG------------------K------------------ESREFN
G
K
E
Y
I
L
E
R
AITGD
Y
G
L
I
K
A
YKSDT
L
G
N
L
V
F
R
K
TARNF
N
-
P
L
C
A
M
A
A
K
I
C
V
A
E
V
E
E
IVPAGEL
D
P
D
EIHL
P
G
I
Y
V
Q
H
I
YK
G
E
K
F
E
K
R
I
E
K
TTTRSAK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
96.33
97%
-113
- C6 -
3RRL
-
SCOA_HELPY
A:
[5-233]
-
N
K
V
I
T
-
D
L
D
K
A
L
S
A
L
K
D
G
D
T
I
L
V
G
G
F
G
L
C
G
I
P
E
Y
A
I
D
Y
I
Y
K
K
G
I
K
D
L
I
V
V
S
N
N
C
G
V
D
D
F
G
L
G
I
L
L
E
K
K
Q
I
K
K
I
I
A
S
Y
V
G
E
N
K
I
F
E
S
Q
M
L
N
G
E
I
E
V
V
L
T
P
Q
G
T
L
A
E
N
L
H
A
G
G
A
G
I
P
A
Y
Y
T
P
T
G
V
G
T
L
I
A
Q
G
------------------
K
------------------
E
S
R
E
F
N
G
K
E
Y
I
L
E
R
A
I
T
G
D
Y
G
L
I
K
A
Y
K
S
D
T
L
G
N
L
V
F
R
K
T
A
R
N
F
N
-
P
L
C
A
M
A
A
K
I
C
V
A
E
V
E
E
I
V
P
A
G
E
L
D
P
D
E
I
H
L
P
G
I
Y
V
Q
H
I
Y
K
G
E
K
F
E
K
R
I
E
K
I
T
T
R
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
95.94
96%
-114
- C6 -
3RRL
-
SCOA_HELPY
A:
[4-233]
-
M
N
K
V
I
T
D
L
D
K
A
L
S
A
L
K
D
G
D
T
I
L
V
G
G
F
G
L
C
G
I
P
E
Y
A
I
D
Y
I
Y
K
K
G
I
K
D
L
I
V
V
S
N
N
C
G
V
D
D
F
G
L
G
I
L
L
E
K
K
Q
I
K
K
I
I
A
S
Y
V
G
E
N
K
I
F
E
S
Q
M
L
N
G
E
I
E
V
V
L
T
P
Q
G
T
L
A
E
N
L
H
A
G
G
A
G
I
P
A
Y
Y
T
P
T
G
V
G
T
L
I
A
Q
G
------------------
K
------------------
E
S
R
E
F
N
G
K
E
Y
I
L
E
R
A
I
T
G
D
Y
G
L
I
K
A
Y
K
S
D
T
L
G
N
L
V
F
R
K
T
A
R
N
F
N
-
P
L
C
A
M
A
A
K
I
C
V
A
E
V
E
E
I
V
P
A
G
E
L
D
P
D
E
I
H
L
P
G
I
Y
V
Q
H
I
Y
K
G
E
K
F
E
K
R
I
E
K
I
T
T
R
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
80.03
55%
-96
- C6 -
1OPE
1
SCOT1_PIG
B:
[2-246]
--
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSIA
I
A
S
K
P
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
V
R
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
79.83
55%
-98
- C6 -
1OOZ
-
SCOT1_PIG
A:
[2-246]
--
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSIA
I
A
S
K
P
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
D
N
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
79.77
55%
-98
- C6 -
1O9L
1
SCOT1_PIG
A:
[2-246]
--
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSIA
I
A
S
K
P
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
K
N
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
79.61
59%
-93
* C6 *
3K6M
1
SCOT1_PIG
A:
[1-245]
-
T
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
------------------
G
SPIKYNKDGSIA
I
A
S
K
P
R
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
-
L
P
M
C
K
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
V
R
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
55
Fugue
79.51
58%
-96
- C6 -
1O9L
2
SCOT1_PIG
A:
[1-481]
-
T
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSIA
I
A
S
K
P
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
-
L
P
M
C
K
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
K
N
V
R
E
R
I
I
K
R
A
A
L
E
FEDG
M
Y
A
N
L
G
IG
I
P
L
L
A
S
N
F
ISPN
M
T
V
H
L
Q
S
ENGI
L
G
L
G
P
YPLQNEVDADLINAGK
E
T
V
T
V
L
P
G
A
S
Y
F
S
S
D
E
S
F
A
M
I
R
G
GHVN
L
T
M
L
G
A
MQVSKYG
D
L
A
N
WMIPGKLVKGMGG
A
M
D
L
V
SSAK
T
K
V
V
V
T
M
E
HSAKGNAHKIMEKCTLPLTGKQCVN
R
I
I
T
EK
A
V
F
D
V
D
RKK
G
L
T
L
IELWEGLT
V
D
D
I
K
K
S
TG
C
D
F
A
V
S
PKLIP
M
Q
Q
V
T
T
5
PsiBlast_PDB
79.39
55%
-91
- C6 -
3K6M
1
SCOT1_PIG
A:
[2-246]
--
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSIA
I
A
S
K
P
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
V
R
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
79.34
55%
-93
- C6 -
3OXO
1
SCOT1_PIG
E:
[2-246]
--
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSIA
I
A
S
K
P
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
R
I
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
79.16
55%
-93
- C6 -
3OXO
1
SCOT1_PIG
H:
[2-246]
--
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSIAIASKP
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
R
A
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
79.10
55%
-93
- C6 -
3OXO
1
SCOT1_PIG
D:
[2-246]
--
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSIA
I
A
S
K
P
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
D
N
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
79.05
55%
-94
- C6 -
1OPE
1
SCOT1_PIG
A:
[2-246]
--
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYIA
I
A
S
K
P
-----
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
V
R
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
78.98
55%
-93
- C6 -
3OXO
-
SCOT1_PIG
A:
[2-246]
--
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSIA
I
A
S
K
P
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
K
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
78.86
56%
-95
- C6 -
3DLX
1
SCOT1_HUMAN
A:
[2-247]
-
T
K
F
Y
T
-
D
P
V
E
A
V
K
D
I
P
D
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
D
A
L
L
K
T
G
V
K
G
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
R
S
K
Q
I
K
R
M
V
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
S
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
P
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSVA
I
A
S
K
P
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
T
G
D
F
A
L
V
K
A
W
K
A
D
R
A
G
N
V
I
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
A
F
A
P
E
D
I
H
I
P
Q
I
Y
V
H
R
L
I
K
G
E
K
Y
E
K
R
I
E
R
L
S
I
R
K
P
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
78.83
55%
-93
- C6 -
3OXO
1
SCOT1_PIG
B:
[2-246]
--
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSIA
I
A
S
K
P
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
K
V
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
78.77
66%
-98
- C6 -
3CDK
-
SCOA_BACSU
A:
[4-232]
-
G
K
V
L
S
-
S
S
K
E
A
A
K
L
I
H
D
G
D
T
L
I
A
G
G
F
G
L
C
G
I
P
E
Q
L
I
L
S
I
R
D
Q
G
V
K
D
L
T
V
V
S
N
N
C
G
V
D
D
W
G
L
G
L
L
L
A
N
K
Q
I
K
K
M
I
A
S
Y
V
G
E
N
K
I
F
E
R
Q
F
L
S
G
E
L
E
V
E
L
V
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
I
P
G
F
Y
T
A
T
G
V
G
T
S
I
A
E
G
------------------
K
------------------
E
H
K
T
F
G
G
R
T
Y
V
L
E
R
G
I
T
G
D
V
A
I
V
K
A
W
K
A
D
T
M
G
N
L
I
F
R
K
T
A
R
N
F
N
-
P
I
A
A
M
A
G
K
I
T
I
A
E
A
E
E
I
V
E
A
G
E
L
D
P
D
H
I
H
T
P
G
I
Y
V
Q
H
V
V
L
G
A
S
Q
E
K
R
I
E
K
R
T
V
Q
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_CBE
78.72
55%
-92
- C6 -
1OOY
1
SCOT1_PIG
B:
[2-246]
--
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSIA
I
A
S
K
P
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
K
E
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
78.68
66%
-100
- C6 -
3CDK
-
SCOA_BACSU
A:
[4-232]
--
G
K
V
L
S
S
S
K
E
A
A
K
L
I
H
D
G
D
T
L
I
A
G
G
F
G
L
C
G
I
P
E
Q
L
I
L
S
I
R
D
Q
G
V
K
D
L
T
V
V
S
N
N
C
G
V
D
D
W
G
L
G
L
L
L
A
N
K
Q
I
K
K
M
I
A
S
Y
V
G
E
N
K
I
F
E
R
Q
F
L
S
G
E
L
E
V
E
L
V
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
I
P
G
F
Y
T
A
T
G
V
G
T
S
I
A
E
G
------------------
K
------------------
E
H
K
T
F
G
G
R
T
Y
V
L
E
R
G
I
T
G
D
V
A
I
V
K
A
W
K
A
D
T
M
G
N
L
I
F
R
K
T
A
R
N
F
N
-
P
I
A
A
M
A
G
K
I
T
I
A
E
A
E
E
I
V
E
A
G
E
L
D
P
D
H
I
H
T
P
G
I
Y
V
Q
H
V
V
L
G
A
S
Q
E
K
R
I
E
K
R
T
V
Q
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
78.65
55%
-93
- C6 -
3OXO
1
SCOT1_PIG
F:
[2-246]
--
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSIA
I
A
S
K
P
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
E
R
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
78.63
55%
-93
- C6 -
3OXO
1
SCOT1_PIG
C:
[2-246]
--
K
F
Y
T
-
D
A
V
E
A
V
K
D
I
P
N
G
A
T
V
L
V
G
G
F
G
L
C
G
I
P
E
N
L
I
G
A
L
L
K
T
G
V
K
E
L
T
A
V
S
N
N
A
G
V
D
N
F
G
L
G
L
L
L
Q
S
K
Q
I
K
R
M
I
S
S
Y
V
G
E
N
A
E
F
E
R
Q
Y
L
A
G
E
L
E
V
E
L
T
P
Q
G
T
L
A
E
R
I
R
A
G
G
A
G
V
P
A
F
Y
T
S
T
G
Y
G
T
L
V
Q
E
G
GSPIKYNKDGSIA
I
A
S
K
P
R
------------------
E
V
R
E
F
N
G
Q
H
F
I
L
E
E
A
I
R
G
D
F
A
L
V
K
A
W
K
A
D
Q
A
G
N
V
T
F
R
K
S
A
R
N
F
N
L
P
M
C
K
-
A
A
E
T
T
V
V
E
V
E
E
I
V
D
I
G
S
F
A
P
E
D
I
H
I
P
K
I
Y
V
H
R
L
V
K
G
E
K
Y
E
K
R
I
E
R
L
S
V
R
N
V
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------