@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0175: (2016-03-12 )
MFNKKKTIASLIVLSSLASQIALTPISALADTHDTNNIALLQNTNENVPYKYTSTLTFPTLTNQTQEDYKLEIKLALPSGMNYTDLQVSVGGEDITNQVGTTSFDNSTNTVTFKFDKVTSWDSLSKAKVKFDWKTSYSGEGGEAKIDSLVATATATSEDKAGNKSTSTGSLKPKDISAPVVKAEETEITYSPGSDVTEEQFLTDIHASVTDNYDSTISLTSNFTSAVNLAVSGDYSVNVQATDKAGNVSNTLNVTVHVSTPAPVAGANITVNHLDSNGNKIAESDTLTGVVNSNYQSESKKITGYTLETTPTNATGTFTDTPQTVDYIYKKDTVTPTPITVNPVEPVKPVNPVVNKPVTVKPANDNTNPSTSNSVEKTTYSSLPTTGDTDQSKSSTIFGALLLLISAPLLLFKKK
Atome Classification :
(20 SA)
---------------------------------.........10.---.......20...---------.....30........40........50........60...-----.....70....--....80-----.........90........100.......--..110.......120.....-----..130......----------------.140.......150..----------------------------------.....160....--...170......--.180--..----.....190....---...-----200..-.....210...--....220.......230------.......240-------.......--250...----....-260..---..-...270.....--..280....-------------...290-----..-.-------..-..----.300-------------..-......310-.-....-...320----........-.330....-----...340---------..---------------.....350-------------.........360--------------........370.......380.......390.......-------400.......410...----------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------MFN
K
K
K
T
I
A
S
L
I
---
V
L
S
S
L
A
S
Q
I
AL
T
---------
P
I
S
A
L
ADTHDTN
N
I
A
L
L
QNTNENV
P
Y
K
Y
TS
T
L
TFPTLTNQ-----TQE
D
Y
K
L
E
I
K
L
--ALPSG------M
N
Y
T
D
L
Q
V
S
VGGE
D
I
T
NQVG--TTSFDNS--T
N
T
V
T
F
K
FDKVTSWDSL
S
K
A
-----
K
V
K
F
D
WKTSYS----------------GEGGE
A
K
I
D
S
L
V
A
TAT----------------------------------ATSEDKAGNKST--STGSLKPKDISA--P
V
V
K--AE----E
T
E
I
T
YSPGSDV---
T
E
E
-----
Q
F
L
T
D
-
I
H
A
SVTDNYD
S
--
T
I
S
LTSNFT
S
A
V
N
L
A
V
S------G
D
Y
S
V
N
V
Q
A
T-------DKAGNVS--
N
T
L
N
V
T
----
V
H
VS-TPAPV---AG-
A
N
I
T
V
N
H
LDSN--G
N
K
IAESD
T
-------------
L
T
G
V
V------NS-N-------YQ-SE----S
K
-
K
-------------
I
T
-
G
Y
T
L
ETTP--T-NATG-TFTD------TP
Q
T
V
D
Y
I
-
Y
KKDTVTP-----T
P
I
TVN---------PV---------------EPVKPV---------------NPVVNK
P
V
T
V
K---------------PANDNTNPSTSNSVEKTTYSSLPTTGDTDQSKS
S
T
I
F
G
-------
A
L
L
L
L
ISA
P
L
L
LFKKK----------------------------------------------------------------
35
Fugue
74.10
17%
16
* C4 *
4XDN
5
SCC4_YEAST
A:
[24-640]
G
D
K
L
S
I
S
Q
V
Y
H
L
A
Q
E
Y
R
D
H
A
Y
S
I
A
NKIGS
E
E
G
L
K
Q
Y
Y
G
L
M
N
M
S
I
Q
---
M
F
Q
L
L
K
T
K
C
T
L
S
---------
V
L
E
D
S
K
V
T
F
E
M
V
E
L
L
I
Q
E
T
Y
N
F
D
L
A
E
L
Y
I
S
S
L
K
E
R
L
Q
T
H
Q
SDTDL
V
E
E
I
M
R
C
E
F
L
L
L
H
D
L
P
L
M
R
DS
K
F
H
Y
K
I
A
L
R
N
C
N
E
L
V
Q
Y
M
V
N
L
Q
D
--
E
L
Y
Q
N
W
A
--
S
V
F
Q
Y
V
G
V
M
L
C
I
K
L
K
Q
H
R
R
V
-----
K
T
S
F
H
G
L
L
S
Q
C
----------------
R
E
K
S
Q
W
K
W
F
L
N
L
C
Y
V
N
----------------------------------
Y
L
L
N
E
R
F
P
I
P
E
D
--
A
L
Q
E
L
R
S
T
E
L
H
T
VG
P
E
L
Y
--
A
W
K
L
A
L
E
M
V
I
Q
L
C
K
D
G
N
I
---
T
D
H
L
N
E
F
K
N
F
F
D
T
-
N
K
Q
S
L
V
T
N
E
G
K
GC
V
I
K
I
M
P
R
I
A
L
K
V
E
L
P
M
I
FH
Y
K
E
L
K
N
I
L
L
L
L
Q
S
V
S
Y
I
VNCY
D
E
K
G
N
F
S
--
R
K
F
L
P
K
----
V
Y
S
T
-
T
Q
K
L
I
K
N
I
A
A
-
G
G
V
S
M
N
E
L
D
S
R
--
I
Q
T
Y
K
S
I
L
E
-------------
F
C
E
F
Y
------
K
V
-
W
-------
E
Q
-
T
L
----
L
K
-
G
AVVLGPSPG
Y
V
R
L
L
Q
-
A
M
K
V
Q
F
E
G
--
G
-
G
A
V
E
-
E
Y
T
R
L
A
Q
SGG
T
S
S
E
V
K
M
I
-
S
L
L
N
C
Y
T
V
-----
Q
A
A
R
V
S
R
CSGDK
Q
G
E
L
V
---------------
E
Q
C
N
K
V
W
L
Q
V
E
K
L
L
Q
E
T
DLQF
N
P
I
W
E
C
T
V
T
I
L
---------------
W
L
F
S
H
F
E
P
F
S
W
N
P
L
P
C
S
D
K
Q
R
A
E
Y
V
S
K
L
R
E
F
Y
S
S
N
K
F
V
NRFKLKK
A
L
L
L
Q
I
L
V
N
Y
L
G
G
R
M
L
EHD
L
G
E
I
Y
A
I
S
A
K
C
F
D
M
C
R
QQGGM
R
K
V
Q
Y
V
I
G
I
W
H
L
M
N
C
T
V
A
MR
G
K
D
V
A
L
T
N
A
K
L
E
A
L
V
K
Q
I
T
S
32
Fugue
71.78
21%
30
- C3 -
2YN5
5
?
A:
[1-283]
-----------------------------------------------------------
T
---------
P
P
N
A
--------------------
P
V
V
T
Y
S
D
I
V
N
D
L
I
I
M
Q
-----
G
T
A
E
A
K
S
Q
L
I
I
--
T
D
S
E
G
----------------------
N
T
Y
T
--
L
T
V
P
D
N
G
--
K
W
S
M
A
I
P
Y
--------
P
S
E
G
-----
K
F
T
I
T
S
V
D
A
I
G
----------------
N
R
S
D
D
V
P
L
D
I
M
K
E
V
P
V
----------------------------------
I
S
L
S
P
D
S
D
S
G
T
V
--
G
D
N
I
T
R
D
K
Q
P
T
F
--
I
I
G
N
--
L
E
-------------
S
D
V
---
V
V
V
-----
Q
V
D
I
N
----
G
T
V
Y
N
A
E
K
--
N
A
D
G
V
W
F
F
T
P
G
T
P
L
A
-
D
------
G
S
Y
T
I
S
V
I
A
S
-------
D
A
A
G
N
Q
K
--
N
S
L
P
I
T
----
V
T
I
D
-
S
T
L
T
V
---
P
---
E
I
A
L
A
A
G
E
D
N
--
G
A
S
--
D
S
D
N
-------------
V
T
N
H
T
------
Q
P
-
K
-------
F
T
-
L
Q
HI--
D
A
-
D
-------------
V
T
-
G
V
T
V
N
V
T
H
--
N
-
G
V
T
D
-
I
Y
Q
A
------
T
Q
G
A
D
G
W
T
-
F
------------
T
P
-------------------------------
P
A
A
W
N
---------------
D
G
N
Y
T
L
S
V
T
V
V
---------------
D
R
A
G
N
S
Q
Q
S
A
S
L
A
V
T
V
D
S
-----------------------------------------------------------------------------------------------------------
30
Fugue
68.40
13%
-1
- C6 -
3VEN
6
TOBZ_STRSD
A:
[6-576]
-----------------------H
M
R
V
L
G
L
N
G
W
P
R
D
F
H
D
A
S
A
A
L
L
V
DG
R
I
A
A
F
A
E
E
E
R
L
T
RKKHGYNTA
P
V
Q
A
A
A
F
C
L
A
Q
A
G
L
T
V
D
D
L
--
D
A
V
A
F
G
W
D
L
P
A
M
Y
R
E
R
L
G
G
-----
W
P
H
S
D
S
E
A
L
D
I
--
L
L
P
R
D
------
V
F
P
R
R
T
D
P
P
L
H
F
V
Q
H
H
L
A
H
A
--
A
S
A
Y
Y
F
S
GE
D
R
G
A
V
L
I
V
D
G
Q
G
E
E
E
C
V
T
L
A
H
A
E
GG
K
I
T
V
L
D
T
V
P
G
A
WS
L
G
F
F
Y
E
H
V
S
E
Y
T
GL
G
G
D
N
P
G
K
L
M
G
L
A
A
H
G
T
TVDETLSA
F
A
F
D
SD
G
Y
R
L
NLIDPQARDPEDWDE
Y
S
V
T
E
R
A
W
F
A
H
L
E
--
R
I
Y
R
L
P
P
N
E
F
V
R
--
R
Y
D
P
--
A
K
----
G
R
V
V
R
D
T
R
R
D
P
Y
---
E
Y
R
-----
D
L
A
A
T
-
A
Q
A
A
L
E
R
A
V
F
G
--
L
A
D
S
V
L
A
R
T
G
E
R
T
L
F
V
A
------
G
G
V
G
L
N
A
T
M
N
-------
G
K
L
L
T
R
S
TV
D
K
M
F
V
P
----
P
V
A
S
-
D
I
G
V
S
---
L
G
-
A
A
A
A
V
A
V
E
L
G
D
--
R
I
A
P
M
G
D
T
A
-------------
A
W
G
P
E
------
F
S
-
P
-------
D
Q
-
V
R
----
A
A
L
D
-------------
R
T
-
G
L
A
Y
R
E
P
A
N
L
E
-
R
E
V
A
-
A
L
I
A
------
S
G
K
V
V
G
W
A
-
Q
G
R
G
E
V
G
P
RALGQ
R
S
L
L
G
S
---------
A
H
SPT
M
R
D
H
I
N
LRVKDR
E
W
W
R
P
F
---------------
A
P
S
M
L
R
S
V
S
D
Q
V
L
EVDADFPYMI
M
T
T
K
V
R
A
A
Y
A
E
R
L
P
S
V
V
H
E
D
W
S
T
R
P
Q
T
V
T
E
A
S
N
P
R
Y
H
R
M
L
T
-------
E
L
G
D
L
V
G
D
P
V
C
L
N
T
S
F
NDRGEPIVSS
P
A
D
A
L
L
T
F
S
R
L
PIDALAVGP
Y
L
V
T
KDLRH-------------------------
28
Fugue
67.94
33%
0
- C5 -
2KT7
-
?
A:
[34-135]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
T
---
N
N
-
F
T
V
K
V
E
Y
V
D
A
D
--
G
A
E
I
A
P
S
D
T
-------------
L
T
D
---------
Y
-
H
-------
Y
V
-
S
T
----
P
K
-
D
-------------
I
P
-
G
Y
K
L
R
E
I
P
--
H
-
N
A
T
G
-
N
I
T
D
------
T
G
I
I
V
R
Y
I
-
Y
D
K
I
I
D
V
S
-----
Y
V
D
E
T
G
--------------------------
K
D
L
L
P
V
---------------
V
E
I
I
N
S
E
A
A
V
L
---------------
E
H
H
H
H
H
H
----------------------------------------------------------------------------------------------------------------------
15
HHSearch
65.00
41%
-2
- C5 -
2KVZ
-
?
A:
[6-76]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
-
N
Q
V
T
V
N
Y
L
D
E
N
--
N
T
S
I
A
P
S
L
Y
-------------
L
S
G
L
F
------
N
E
-
A
-------
Y
N
-
V
P
----
M
K
-
K
-------------
I
K
-
G
Y
T
L
L
K
Y
D
--
S
-
E
I
L
G
-
V
F
T
E
------
S
P
Q
T
I
N
I
I
-
Y
Q
K
K
A
P
E
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
64.89
46%
1
- C5 -
2KVZ
-
?
A:
[9-71]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
V
N
Y
L
D
E
N
--
N
T
S
I
A
P
S
L
Y
-------------
L
S
G
L
F
------
N
E
-
A
-------
Y
N
-
V
P
----
M
K
-
K
-------------
I
K
-
G
Y
T
L
L
K
Y
D
--
S
-
E
I
L
G
-
V
F
T
E
------
S
P
Q
T
I
N
I
I
-
Y
Q
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
64.70
48%
13
- C5 -
2KT7
-
?
A:
[39-101]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
T
V
K
V
E
Y
V
D
A
D
--
G
A
E
I
A
P
S
D
T
-------------
L
T
---------
D
Y
-
H
-------
Y
V
-
S
T
----
P
K
-
D
-------------
I
P
-
G
Y
K
L
R
E
I
P
--
H
-
N
A
T
G
-
N
I
T
D
------
T
G
I
I
V
R
Y
I
-
Y
D
K
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
63.18
34%
-0
* C5 *
2KVZ
-
?
A:
[1-85]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
F
G
---
K
P
-
N
Q
V
T
V
N
Y
L
D
E
N
--
N
T
S
I
A
P
S
L
Y
-------------
L
S
G
L
F
------
N
E
-
A
-------
Y
N
-
V
P
----
M
K
-
K
-------------
I
K
-
G
Y
T
L
L
K
Y
D
--
S
-
E
I
L
G
-
V
F
T
E
------
S
P
Q
T
I
N
I
I
-
Y
Q
K
K
A
P
E
Q
-----
A
L
E
H
H
H
---------
H
H
---------------
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
62.78
47%
7
- C5 -
2KT7
-
?
A:
[41-100]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
V
E
Y
V
D
A
D
--
G
A
E
I
A
P
S
D
T
-------------
L
T
---------
D
Y
-
H
-------
Y
V
-
S
T
----
P
K
-
D
-------------
I
P
-
G
Y
K
L
R
E
I
P
--
H
-
N
A
T
G
-
N
I
T
D
------
T
G
I
I
V
R
Y
I
-
Y
D
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
59.14
11%
10
- C4 -
1YEW
3
PMOB_METCA
A:
[1-382]
----------------------------------
H
G
E
K
S
Q
A
A
F
M
R
---
M
R
T
-----
I
H
W
Y
---------
D
L
S
W
S
K
E
K
V
K
I
N
E
T
V
E
I
K
G
-------
K
F
H
V
F
E
G
W
P
E
T
V
D
E
-----
P
D
---
V
A
F
L
N
V
--
G
M
P
G
P
------
V
-
F
I
R
K
E
S
Y
I
G
G
Q
L
V
P
R
S
V
R
--
L
E
I
G
K
T
Y
--
D
F
R
V
V
L
K
A
R
R
P
G
D
W
H
V
H
T
M
M
-----
N
V
Q
G
G
--
G
P
I
I
----------------
G
P
G
K
W
I
T
V
E
G
S
M
S
E
F
R
----------------------------------
N
P
V
T
T
L
T
G
Q
T
V
D
LE
N
Y
N
E
G
N
T
Y
F
W
H
A
--
F
W
F
A
--
I
G
----
V
A
W
I
G
Y
W
S
R
R
P
I
---
F
I
P
-----
R
L
L
M
V
-
D
A
G
R
A
D
E
L
V
S
A
--
T
---
D
R
K
V
A
M
G
F
L
A
A
T
I
------
L
I
V
V
M
A
M
S
S
A
-------
N
S
K
Y
P
I
T
--
I
P
L
Q
A
G
----
T
M
R
G
M
K
P
L
E
L
---
P
A
-
P
T
V
S
V
K
V
E
D
A
T
--
Y
R
V
P
G
R
A
M
R
-------------
M
K
L
T
I
------
T
N
-
H
--------
G
-
N
S
----
P
I
-
R
-------------
L
G
-
E
F
Y
---------
T
A
S
V
-
R
F
L
D
------
S
D
V
Y
K
D
T
T
G
Y
P
E
D
L
L
A
E
-----
D
G
L
S
V
S
---------
D
N
---------------
S
P
L
A
P
G
---------------
E
T
R
T
V
D
V
T
A
S
D
---------------
A
A
W
E
V
Y
R
L
S
D
I
I
Y
D
P
D
S
R
F
A
G
L
L
F
F
F
D
A
T
G
N
R
Q
V
V
Q
I
D
-------
A
P
L
I
P
S
F
M
------------------------------------------------------------------------
34
Fugue
55.19
20%
-3
- C5 -
4MT5
-
?
A:
[1-184]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
T
-
A
Y
V
K
Y
V
D
D
T
T
G
--
E
T
L
R
Q
D
D
L
H
G
Y
T
D
E
T
I
P
------
Y
S
T
A
E
G
I
K
K
Y
-------
E
G
D
G
Y
V
L
--
V
S
D
G
F
K
PG
T
K
F
G
V
G
-
T
P
T
Y
E
---
V
H
-
F
K
H
G
M
T
H
T
D
A
T
---
D
K
N
A
E
Q
K
T
-------------
V
T
E
T
I
H
Y
V
D
EN
N
Q
-
T
-------
V
Q
-
P
D
----
S
T
-
T
-------------
A
V
-
T
F
K
R
G
Y
T
T
--
D
-
N
V
T
G
K
V
V
S
Y
------
D
P
W
T
V
D
G
--
N
Q
A
D
S
K
T
F
-----
A
A
V
P
S
P
---------
A
V
---------------
E
G
Y
T
P
N
---------------
H
Q
Q
I
N
-
E
F
T
V
----------------------
T
P
D
S
K
D
I
V
K
T
V
V
Y
V
G
D
P
------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
55.19
40%
-38
- C5 -
4L3A
-
?
A:
[366-423]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
E
K
T
Y
I
E
N
Q
L
V
---
T
E
A
-----
T
F
L
S
D
-
I
H
A
K
T
D
D
G
--
S
--
T
V
--
T
S
D
F
A
D
K
V
D
F
N
T
P
------
G
T
Y
T
V
T
L
Q
S
E
-------
N
N
A
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
55.07
27%
33
- C5 -
4M00
2
SRAP_STAA8
A:
[427-532]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
V
T
----------------------------------
V
V
S
T
D
Q
A
N
N
K
S
T
--
T
T
F
T
I
N
V
V
D
T
T
A
--
P
T
V
T
P
I
G
D
----
Q
S
S
E
V
Y
S
P
I
S
P
I
K
I
A
T
Q
D
-----
N
S
G
N
A
-
V
T
N
T
V
T
G
L
P
S
G
--
L
T
F
D
S
T
N
N
T
I
S
G
T
P
T
N
I
------
G
T
S
T
I
S
I
V
S
T
-------
D
A
S
G
N
K
T
--
T
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
54.83
31%
42
- C5 -
3I57
-
?
A:
[97-184]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
T
V
H
Y
K
Y
A
N
--
G
T
K
A
A
E
D
Q
T
A
Q
V
T
F
T
R
N
G
V
L
DD
V
T
G
I
V
------
A
W
G
K
WNEA
S
Q
S
Y
K
A
L
T
----
S
P
-
T
-------------
I
A
-
G
Y
A
P
S
E
A
V
--
V
K
R
S
S
N
-
S
D
A
E
------
Q
G
P
T
L
T
V
I
-
Y
T
A
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
53.47
27%
32
- C5 -
4M03
1
A:
[96-201]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
V
T
----------------------------------
V
V
S
T
D
Q
A
N
N
K
S
T
--
T
T
F
T
I
N
V
V
D
T
T
A
--
P
T
V
T
P
I
G
D
----
Q
S
S
E
V
Y
S
P
I
S
P
I
KI
A
T
Q
D
-----
N
S
G
N
A
-
V
T
N
T
V
T
G
L
P
S
G
--
L
T
F
D
S
T
N
N
T
I
S
G
T
P
T
N
I
------
G
T
S
T
I
S
I
V
S
T
-------
D
A
S
G
N
K
T
--
T
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
52.30
12%
10
- C5 -
2KVZ
-
?
A:
[8-75]
-------------------------------------------------------------------------------------------------
Q
V
T
V
N
Y
L
D
--
E
N
-----
N
T
S
I
A
P
-
S
L
Y
L
--
S
G
L
F
N
------
E
A
Y
N
V
P
M
K
K
I
K
G
Y
T
L
L
K
Y
D
S
EI
L
G
V
F
T
E
S
--
P
Q
T
I
N
I
I
Y
Q
K
K
A
P
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
51.49
25%
1
* C8 *
4FHO
-
?
A:
[23-163]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
----------------------------------
A
N
A
V
K
T
A
T
G
K
S
N
--
V
T
D
A
V
T
Q
A
D
L
D
G
I-
A
T
L
S
--
A
F
----
N
T
G
V
T
T
I
E
G
I
-------------
Q
Y
L
N
N
L
I
G
L
E
L
K
D
N
Q
I
T
--
D
L
T
P
L
K
N
L
T
K
I
T
E
L
E
L
S
------
G
N
P
L
K
N
V
S
A
I
-------
A
G
L
Q
S
I
K
--
T
L
D
L
T
S
----
T
Q
I
T
-
D
V
T
P
L
---
A
G
L
S
N
L
Q
V
L
Y
L
D
L
----
N
Q
I
T
N
I
S
P
-------------
L
A
G
L
T
------
N
L
-
Q
-------
Y
L
-
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
50.51
22%
4
- C5 -
2KYW
-
?
A:
[4-69]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
T
I
T
Y
V
D
D
D
KG
G
A
Q
V
G
D
I
V
T
-------------
V
T
G
K
T
------
D
D
-
S
-------
T
T
-
Y
-----
T
V
-
T
-------------
I
P
D
G
Y
E
Y
V
G
T
D
--
G
----
G
-
V
V
S
S
------
D
G
K
T
V
T
I
T
-
F
A
A
D
D
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
49.46
22%
22
- C5 -
3I57
1
?
A:
[3-76]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
H
V
Q
Y
I
D
G
E
--
T
D
Q
M
L
R
Q
D
D
-------------
L
D
G
Y
T
------
D
E
-
T
IP-----
Y
S
-
T
A
E
G
I
K
K
F
-
E
-------------
G
D
-
G
Y
E
L
F
K
D
N
--
F
-
P
A
G
E
-
K
F
D
N
DDT---
N
D
Q
F
Y
T
V
I
-
F
K
H
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
48.26
27%
-14
- C8 -
1H6U
-
?
A:
[95-192]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Y
L
N
N
L
I
G
L
E
L
K
D
N
Q
I
T
--
D
L
A
P
L
K
N
L
T
K
I
T
E
L
E
L
S
------
G
N
P
L
K
N
V
S
A
I
-------
A
G
L
Q
S
I
K
--
T
L
D
L
T
S
----
T
Q
I
T
-
D
V
T
P
L
---
A
G
L
S
N
L
Q
V
L
Y
L
D
L
----
N
Q
I
T
N
I
S
P
-------------
L
A
G
L
T
------
N
L
-
Q
-------
Y
L
-
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------