@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0194: (2016-03-13 )
MPKPLIDMKNLTKTYTLGGETFKALDDVTFTVEQGEFLSIVGPSGSGKSTLMNMIGCLDVPDEGSYHLDDVDVFKLSDNKLSEIRNKKIGFIFQQFNLLPKLSAFENVELPLIYAGLSVSAREKAAIECLEKVGLLEKRRNLPTQLSGGQQQRVAIARALAGKPQILLADEPTGALDSKTGKEVMGILQELNRAGNTIVMITHDPTIASYGTRSIRIQDGKLFHEEATQA
Atome Classification :
(37 SA)
.....-....10........20..-......30........40........50........60........70..---------.--....----------.80.--.......90...--.....100......-.110...---.-.---...120.......130...-...-.-140.-..-------.....150.......160.......170.......180.......190-.-.-....-.200..-....-.-210........220.......230--------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MPKPL-
I
D
M
K
NLT
K
T
Y
TLGG
E
T
F
K
-ALD
D
V
T
F
T
VEQG
E
F
L
S
I
VGPSGS
G
K
S
T
L
M
N
M
I
GCLDVPDEGSYHLDD
V
D
V
---------
F
--KLSD----------N
K
L
S
--
E
I
RNK
K
I
G
F
I
F
Q
--
Q
F
NLLPKLSAFENV-EL-
P
L
I
Y
---A-G---LSV
S
A
R
E
K
A
A
I
E
C
L
E
K
V
G
L
-
L
E
K
-R-R-NL-PT-------QLSGG
Q
Q
Q
R
V
A
I
A
R
A
LAGK
P
Q
I
L
L
ADEPTGALDSK
T
G
K
E
V
M
G
I
L
Q
E
L
N
-R-A-G
N
T
I
-
V
M
I
THD-PTIA-S-Y-G
T
R
S
I
R
IQDG
K
L
F
H
E
EATQA----------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
95.52
54%
-102
- C1 -
1L2T
4
Y796_METJA
A:
[1-227]
----
M
-
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
-
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
--
D
L
D
D
----------
D
E
L
T
--
K
I
R
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
-
P
L
I
F
KYR
G
-
A
---
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
-
E
E
R
-
F
-
A
-
N
H
K
P
N
-------
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
D
G
K
T
V
-
V
V
V
T
H
D
-
I
N
V
A
-
R
-
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
--------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
95.44
54%
-108
- C1 -
1L2T
4
Y796_METJA
B:
[1-227]
----
M
-
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
-
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
--
D
L
D
D
----------
D
E
L
T
--
K
I
R
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
-
P
L
I
F
KYR
G
-
A
---
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
-
E
E
R
-
F
-
A
-
N
H
K
P
N
-------
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
D
G
K
T
V
-
V
V
V
T
H
D
-
I
N
V
A
-
R
-
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
--------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
95.33
54%
-100
- C1 -
1F3O
2
Y796_METJA
A:
[2-227]
------
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
-
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
--
D
L
D
D
----------
D
E
L
T
--
K
I
R
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
-
P
L
I
F
K
YR
G
-
A
---
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
-
E
E
R
-
F
-
A
-
N
H
K
P
N
-------
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
E
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
D
G
K
T
V
-
V
V
V
T
H
D
-
I
N
V
A
-
R
-
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
--------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
93.77
53%
-110
- C1 -
3TIF
7
Y796_METJA
B:
[1-227]
----
M
-
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
-
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
--
D
L
D
D
----------
D
E
L
T
--
K
I
R
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
-
P
L
I
F
KYR
G
-
A
---
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
-
E
E
R
-
F
-
A
-
N
H
K
P
N
-------
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
D
G
K
T
V
-
V
V
V
T
H
D
-
I
N
V
A
-
R
-
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
--------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
93.71
53%
-99
- C1 -
3TIF
7
Y796_METJA
A:
[1-227]
----
M
-
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
-
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
--
D
L
D
D
----------
D
E
L
T
--
K
I
R
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
-
P
L
I
F
KYR
G
-
A
---
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
-
E
E
R
-
F
-
A
-
N
H
K
P
N
-------
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
D
G
K
T
V
-
V
V
V
T
H
D
-
I
N
V
A
-
R
-
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
--------------------------------------------------------------------------------------------------------------------
122
HHSearch
92.73
53%
-97
- C1 -
3TIF
7
Y796_METJA
A:
[1-230]
----
M
-
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
-
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
---------
N
--
D
L
D
D
----------
D
E
L
T
--
K
I
R
R
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
-
P
L
I
F
---
K
-
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
-
E
E
R
F
A
-
N
-
H
K
-
P
N
-------
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
E
D
-
G
K
T
V
-
V
V
V
T
H
D
-
I
N
V
A
-
R
-
F
-
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
-----------------------------------------------------------------------------------------------------------------
118
HHSearch
78.35
41%
-90
- C1 -
2PCJ
-
LOLD_AQUAE
A:
[2-223]
--
A
E
I
-
L
R
A
E
N
I
K
K
V
I
R
G
----
Y
E
-
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
---------
D
--
Y
T
N
E
----------
K
E
L
S
--
L
L
R
N
R
K
L
G
F
V
F
Q
--
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
-
I
V
-
P
M
L
K
---
M
-
G
---
K
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
-
G
D
K
-
L
-
S
-
R
K
-
P
Y
-------
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
-
E
-
G
-
G
T
S
I
-
V
M
V
T
H
E
-
R
E
L
A
-
E
-
L
-
T
H
R
T
L
E
M
K
D
G
K
V
V
G
E
I
T
R
------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
76.56
42%
-106
- C1 -
4YMW
-
?
J:
[13-217]
---------------------
S
L
E
-
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
---------
N
NG
K
V
N
I
----------
N
K
V
R
--
Q
----
K
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A
P
V
K
V
---
K
-
K
---
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
-
L
D
K
-
K
-
D
-
Q
Y
-
P
I
-------
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
-
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
---------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
75.87
42%
-87
- C1 -
4U00
3
?
A:
[3-219]
---
P
I
-
I
R
I
R
N
L
H
K
W
F
G
----
P
L
H
-
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
-------------
K
D
D
----------
R
A
L
R
--
E
I
R
-
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
-
T
L
A
P
M
R
V
---
R
-
R
---
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
-
L
D
Q
-
A
-
R
-
K
Y
-
P
A
-------
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
-
Q
-
G
-
G
M
T
M
-
V
V
V
T
H
E
-
M
G
F
A
-
R
-
E
-
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
--------------------------------------------------------------------------------------------------------------------
126
Fugue
75.42
38%
-99
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
---
H
M
-
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
-
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
---------
T
--
T
L
S
E
----------
S
E
L
T
--
K
A
R
R
Q
-
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
---
D
-
N
---
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
-
G
D
K
-
H
-
D
-
S
Y
-
P
S
-------
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
-
R
-
R
L
G
L
T
I
-
L
L
I
T
H
E
M
D
V
V
K
-
R
-
I
-
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
VFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV
7
PsiBlast_PDB
75.26
42%
-82
- C1 -
4U02
1
?
A:
[2-219]
--
E
P
I
-
I
R
I
R
N
L
H
K
W
F
G
----
P
L
H
-
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
-------------
K
D
D
----------
R
A
L
R
--
E
I
R
-
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
-
T
L
A
P
M
R
V
---
R
-
R
---
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
-
L
D
Q
-
A
-
R
-
K
Y
-
P
A
-------
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
-
Q
-
G
-
G
M
T
M
-
V
V
V
T
H
E
-
M
G
F
A
-
R
-
E
-
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
--------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
75.20
42%
-87
- C1 -
4U02
1
?
C:
[2-219]
--
E
P
I
-
I
R
I
R
N
L
H
K
W
F
G
----
P
L
H
-
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
-------------
K
D
D
----------
R
A
L
R
--
E
I
R
-
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
-
T
L
A
P
M
R
V
---
R
-
R
---
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
-
L
D
Q
-
A
-
R
-
K
Y
-
P
A
-------
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
-
Q
-
G
-
G
M
T
M
-
V
V
V
T
H
E
-
M
G
F
A
-
R
-
E
-
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
--------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
74.85
42%
-104
- C1 -
4YMV
1
?
A:
[13-217]
---------------------
S
L
E
-
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
---------
N
NG
K
V
N
I
----------
N
K
V
R
--
Q
----
K
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A
P
V
K
V
---
K
-
K
---
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
-
L
D
K
-
K
-
D
-
Q
Y
-
P
I
-------
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
-
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
---------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
74.77
42%
-84
- C1 -
4U02
1
?
B:
[2-219]
--
E
P
I
-
I
R
I
R
N
L
H
K
W
F
G
----
P
L
H
-
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
-------------
K
D
D
----------
R
A
L
R
--
E
I
R
-
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
-
T
L
A
P
M
R
V
---
R
-
R
---
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
-
L
D
Q
-
A
-
R
-
K
Y
-
P
A
-------
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
-
Q
-
G
-
G
M
T
M
-
V
V
V
T
H
E
-
M
G
F
A
-
R
-
E
-
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
--------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
74.77
42%
-83
- C1 -
4U02
1
?
D:
[2-219]
--
E
P
I
-
I
R
I
R
N
L
H
K
W
F
G
----
P
L
H
-
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
-------------
K
D
D
----------
R
A
L
R
--
E
I
R
-
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
-
T
L
A
P
M
R
V
---
R
-
R
---
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
-
L
D
Q
-
A
-
R
-
K
Y
-
P
A
-------
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
-
Q
-
G
-
G
M
T
M
-
V
V
V
T
H
E
-
M
G
F
A
-
R
-
E
-
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
E
E
--------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
74.57
42%
-105
- C1 -
4YMV
1
?
J:
[13-217]
---------------------
S
L
E
-
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
---------
N
NG
K
V
N
I
----------
N
K
V
R
--
Q
----
K
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A
P
V
K
V
---
K
-
K
---
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
-
L
D
K
-
K
-
D
-
Q
Y
-
P
I
-------
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
-
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
---------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
74.34
42%
-102
- C1 -
4YMU
2
?
J:
[13-217]
---------------------
S
L
E
-
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
---------
N
NG
K
V
N
I
----------
N
K
V
R
--
Q
----
K
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A
P
V
K
V
---
K
-
K
---
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
-
L
D
K
-
K
-
D
-
Q
Y
-
P
I
-------
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
-
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
---------------------------------------------------------------------------------------------------------------------
110
HHSearch
74.33
36%
-86
- C1 -
1OXX
21
?
K:
[2-226]
---
V
R
-
I
I
V
K
N
V
S
K
V
F
K
K
G
--
K
V
V
-
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
R
L
V
---------
A
--
S
N
G
K
----------
L
I
V
P
---
P
E
D
R
K
I
G
M
V
F
Q
--
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
-
A
F
-
P
L
T
N
---
M
-
K
---
M
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
L
D
I
-
H
H
V
-
L
-
N
-
H
F
-
P
R
-------
E
L
S
G
A
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
-
L
-
G
V
T
L
-
L
V
V
S
H
D
-
P
A
D
I
-
F
A
I
-
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
-----------------------------------------------------------------------------------------------------------------
104
HHSearch
74.28
39%
-98
* C1 *
3TUI
1
METN_ECOLI
C:
[23-249]
---
H
M
-
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
-
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
---------
T
--
T
L
S
E
----------
S
E
L
T
--
K
A
R
-
R
Q
I
G
M
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
-
P
L
E
L
---
D
-
N
---
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
-
G
D
K
-
H
-
D
-
S
Y
-
P
S
-------
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
-
L
-
G
L
T
I
-
L
L
I
T
H
E
-
M
D
V
V
-
K
R
I
-
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
-----------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
74.19
42%
-107
- C1 -
4YMS
-
?
J:
[13-217]
---------------------
S
L
E
-
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
---------
N
NG
K
V
N
I
----------
N
K
V
R
--
Q
----
K
V
G
M
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
A
P
V
K
V
---
K
-
K
---
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
-
L
D
K
-
K
-
D
-
Q
Y
-
P
I
-------
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
-
V
V
V
T
H
E
-
M
G
F
A
R
E
-
V
-
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
---------------------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
73.60
37%
-95
- C1 -
1B0U
4
HISP_SALTY
A:
[11-234]
----------
D
L
H
K
R
Y
--
G
G
H
--
E
-
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
N
I
N
L
V
R
D
KDGQ
L
--
K
V
A
D
----------
K
N
Q
L
--
R
L
L
R
T
R
L
T
M
V
F
Q
--
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
-
P
I
Q
V
---
L
-
G
---
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
-
D
E
R
-
A
-
Q
G
K
Y
-
P
V
-------
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
-
E
-
E
-
G
K
T
M
-
V
V
V
T
H
E
-
M
G
F
A
-
R
-
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
---------------------------------------------------------------------------------------------------------------------
124
HHSearch
72.37
38%
-96
- C1 -
1B0U
4
HISP_SALTY
A:
[5-238]
---
N
K
-
L
H
V
I
D
L
H
K
R
Y
G
G
----
H
E
-
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
N
I
---------
N
--
L
V
R
D
KDGQLKVAD
K
N
Q
L
R
--
L
L
-
R
T
R
L
T
M
V
F
Q
--
H
F
N
L
W
S
H
M
T
V
L
E
N
V
-
M
E
-
A
P
I
Q
---
V
L
G
---
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
-
D
E
R
-
A
Q
G
-
K
Y
-
P
V
-------
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
-
E
-
E
-
G
K
T
M
-
V
V
V
T
H
E
-
M
G
F
A
-
R
H
V
-
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
-----------------------------------------------------------------------------------------------------------------
88
PsiBlast_CBE
66.55
32%
-91
- C1 -
4MKI
4
ECFA2_CALS4
B:
[5-226]
----
M
P
I
K
V
E
N
V
S
F
I
Y
N
E
G
T
P
Y
A
T
V
A
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
G
I
D
I
--------------
T
D
----------
K
K
V
S
L
K
D
I
R
-
K
Q
V
G
L
V
F
Q
YP
E
Y
Q
L
F
E
E
-
T
V
F
K
D
I
-
A
F
-
G
P
S
N
---
L
-
G
---
L
S
E
E
E
V
K
E
R
V
Y
E
A
M
E
I
V
G
I
S
K
E
L
-
A
-
D
-
K
S
-
P
F
-------
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
K
E
I
H
-
D
-
K
-
Y
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
-
R
-
I
-
A
D
K
I
I
V
M
N
R
G
K
I
------------------------------------------------------------------------------------------------------------------------
89
PsiBlast_CBE
66.27
32%
-92
- C1 -
4MKI
4
ECFA2_CALS4
A:
[3-226]
--
R
P
M
P
I
K
V
E
N
V
S
F
I
Y
N
E
G
T
P
Y
A
T
V
A
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
G
I
D
I
--------------
T
D
----------
K
K
V
S
L
K
D
I
R
-
K
Q
V
G
L
V
F
Q
YP
E
Y
Q
L
F
E
E
-
T
V
F
K
D
I
-
A
F
-
G
P
S
N
---
L
-
G
---
L
S
E
E
E
V
K
E
R
V
Y
E
A
M
E
I
V
G
I
S
K
E
L
-
A
-
D
-
K
S
-
P
F
-------
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
K
E
I
H
-
D
-
K
-
Y
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
-
R
-
I
-
A
D
K
I
I
V
M
N
R
G
K
I
------------------------------------------------------------------------------------------------------------------------
94
PsiBlast_CBE
59.60
32%
-83
- C1 -
2FGK
2
D:
[25-224]
--------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
---------
A
--
L
A
D
P
----------
N
W
L
------
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
-
A
--
N
---
P
-
G
---
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
-
E
-
G
Y
-
N
T
IVGEQGA
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
-
K
---
G
R
T
V
-
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
---------------------------------------------------------------------------------------------------------------------
93
PsiBlast_CBE
59.39
32%
-86
- C1 -
3B5J
1
A:
[21-220]
--------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
A
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
---------
A
--
L
A
D
P
----------
N
W
L
------
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
-
A
--
N
---
P
-
G
---
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
-
E
-
G
Y
-
N
T
IVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
-
K
---
G
R
T
V
-
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
---------------------------------------------------------------------------------------------------------------------
102
PsiBlast_CBE
59.32
32%
-86
- C1 -
2FGJ
2
HLYBP_ECOLX
A:
[25-224]
--------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
---------
A
--
L
A
D
P
----------
N
W
L
------
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
-
A
--
N
---
P
-
G
---
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
-
E
-
G
Y
-
N
T
IVGEQ
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
-
K
---
G
R
T
V
-
I
I
I
A
A
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
---------------------------------------------------------------------------------------------------------------------
92
PsiBlast_CBE
59.09
33%
-85
- C1 -
2PMK
1
A:
[21-220]
--------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
---------
A
--
L
A
D
P
----------
N
W
L
------
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
-
A
--
N
---
P
-
G
---
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
-
E
-
G
Y
-
N
T
IVGEQGA
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
-
K
---
G
R
T
V
-
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
---------------------------------------------------------------------------------------------------------------------
99
PsiBlast_CBE
58.96
32%
-84
- C1 -
2FGJ
2
D:
[25-224]
--------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
---------
A
--
L
A
D
P
----------
N
W
L
------
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
-
A
--
N
---
P
-
G
---
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
-
E
-
G
Y
-
N
T
IVGEQGA
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
-
K
---
G
R
T
V
-
I
I
I
A
A
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
---------------------------------------------------------------------------------------------------------------------
96
PsiBlast_CBE
58.92
32%
-83
- C1 -
2FGK
2
HLYBP_ECOLX
B:
[25-224]
--------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
---------
A
--
L
A
D
P
----------
N
W
L
------
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
-
A
--
N
---
P
-
G
---
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
-
E
-
G
Y
-
N
T
IVGEQGA
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
-
K
---
G
R
T
V
-
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
---------------------------------------------------------------------------------------------------------------------
100
PsiBlast_CBE
58.83
32%
-87
- C1 -
2FGJ
2
HLYBP_ECOLX
C:
[25-224]
--------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
---------
A
--
L
A
D
P
----------
N
W
L
------
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
-
A
--
N
---
P
-
G
---
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
-
E
-
G
Y
-
N
T
IVGEQGA
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
-
K
---
G
R
T
V
-
I
I
I
A
A
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
---------------------------------------------------------------------------------------------------------------------
90
PsiBlast_CBE
58.61
33%
-84
- C1 -
2FF7
1
A:
[25-224]
--------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
---------
A
--
L
A
D
P
----------
N
W
L
------
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
-
A
--
N
---
P
-
G
---
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
-
E
-
G
Y
-
N
T
IVGEQGA
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
-
K
---
G
R
T
V
-
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
---------------------------------------------------------------------------------------------------------------------
101
PsiBlast_CBE
58.30
32%
-85
- C1 -
2FGJ
2
HLYBP_ECOLX
B:
[25-224]
--------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
---------
A
--
L
A
D
P
----------
N
W
L
------
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
-
A
--
N
---
P
-
G
---
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
-
E
-
G
Y
-
N
T
IVGEQGA
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
-
K
---
G
R
T
V
-
I
I
I
A
A
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
---------------------------------------------------------------------------------------------------------------------
95
PsiBlast_CBE
58.29
32%
-87
- C1 -
2FGK
2
HLYBP_ECOLX
C:
[25-224]
--------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
---------
A
--
L
A
D
P
----------
N
W
L
------
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
-
A
--
N
---
P
-
G
---
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
-
E
-
G
Y
-
N
T
IVGEQGA
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
-
K
---
G
R
T
V
-
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
---------------------------------------------------------------------------------------------------------------------
103
PsiBlast_CBE
57.84
32%
-84
- C1 -
2FFA
2
A:
[25-224]
--------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
---------
A
--
L
A
D
P
----------
N
W
L
------
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
-
A
--
N
---
P
-
G
---
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
-
E
-
G
Y
-
N
T
IVGEQGA
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
-
K
---
G
R
T
V
-
I
I
I
A
A
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
---------------------------------------------------------------------------------------------------------------------
97
PsiBlast_CBE
57.33
32%
-85
- C1 -
2FGK
2
HLYBP_ECOLX
A:
[25-224]
--------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
---------
A
--
L
A
D
P
----------
N
W
L
------
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
-
A
--
N
---
P
-
G
---
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
-
E
-
G
Y
-
N
T
I
V
G
EQGA
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
-
K
---
G
R
T
V
-
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
---------------------------------------------------------------------------------------------------------------------
98
PsiBlast_CBE
57.12
32%
-85
- C1 -
2FFB
1
A:
[25-224]
--------------------------
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
H
D
L
---------
A
--
L
A
D
P
----------
N
W
L
------
R
R
Q
V
G
V
V
L
Q
--
D
-
N
V
L
L
N
R
S
I
I
D
N
I
-
S
L
-
A
--
N
---
P
-
G
---
M
S
V
E
K
V
I
Y
A
A
K
L
A
G
A
H
D
F
I
-
S
E
L
-
R
-
E
-
G
Y
-
N
T
IVGEQG
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
E
S
E
H
V
I
M
R
N
M
H
K
I
C
-
K
---
G
R
T
V
-
I
I
I
A
H
R
-
L
S
T
V
-
K
-
N
-
A
D
R
I
I
V
M
E
K
G
K
I
V
E
Q
---------------------------------------------------------------------------------------------------------------------