@TOME V2.3
(Nov 2016)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0957: (2016-03-20 )
MQLITTENKLAGSKKALEIIEKGITSGEVNTLGLATGSTPETLYAELVKSDVDTKNVTTTNLDEYVGLAASDPNSYHYYMNDLLFSKKAFKESFLPNGEATDAEAECARYEEILSEHPIDIQVLGIGTNGHIGFNEPGTSFDSITHKVVLTDSTREANKRFFEREEDVPTHAYSMGIKSIMNAKKIILLAFGENKAQAIKETIKGPVDVNCPASVLQNHPDVTVILDNEAASLL
Atome Classification :
(27 SA)
.........10........20...-----.-----.-----.-----..30----.........40........----50---.----........60........70........80.......--.90-...--.--.....100.......110-..-...-.-.120.......130.......140.......150...-....160.-.-.-....170.......180.......190.......200.......210.......220.......230..----------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
Q
L
I
TTENKLAG
S
K
K
A
L
E
I
I
E
KGI-----T-----S-----G-----E
V
N
-----
T
L
G
LATGS
T
P
E
T
L
Y
A
E
L
V
K----S----D----VDTKNVTTT
N
L
D
E
Y
VGLAASDPN
S
Y
H
Y
Y
M
N
D
L
L
F
S
K
K
--
A
F
--
K
E
S--F--LPNGEATD
A
E
A
E
C
A
R
Y
E
E
-
I
L
-
S
EH-P-
I
D
I
Q
V
L
G
I
GTNGHIGFNEPGTSFDS
I
T
H
K
V
V
L
TDST
R
-
E
A
N
K
R
F
F
E
-
R
-E-EDVP
T
H
A
Y
S
M
G
I
K
S
I
MNA
K
K
I
I
L
L
A
FGE
N
K
A
Q
A
I
K
E
T
IKGPVDVNC
P
A
S
V
L
QNHP
D
V
T
V
I
LDN
E
A
A
SLL----------------------------------
1
PsiBlast_PDB
98.32
54%
-87
- C5 -
2RI0
1
NAGB_STRMU
A:
[2-232]
M
K
T
I
K
V
K
N
K
T
E
G
S
K
V
A
F
R
M
L
E
E
E
I
-----
T
-----
F
-----
G
------
A
K
-----
T
L
G
L
A
T
G
S
T
P
L
E
L
Y
K
E
I
R
E
----
S
----
H
----
L
D
F
S
D
M
V
S
I
N
L
D
E
Y
V
G
L
S
A
D
D
K
Q
S
Y
A
Y
F
M
K
Q
N
L
F
A
A
K
--
P
F
--
K
K
S
--
Y
--
L
P
N
G
L
A
A
D
L
A
K
E
T
E
Y
Y
D
Q
-
I
L
-
A
Q
Y
-
P
-
I
D
L
Q
I
L
G
I
G
R
N
A
H
I
G
F
N
E
P
G
T
A
F
S
S
Q
T
H
L
V
D
L
T
P
S
T
I
-
A
A
N
S
R
F
F
E
-
K
-
A
-
E
D
V
P
K
Q
A
I
S
M
G
L
A
S
I
M
S
A
K
M
I
L
L
M
A
F
G
E
E
K
A
E
A
V
A
A
M
V
K
G
P
V
T
E
E
I
P
A
S
I
L
Q
T
H
P
K
V
I
L
I
V
D
E
K
A
G
A
------------------------------------
21
PsiBlast_CBE
98.06
54%
-85
- C5 -
2RI0
3
NAGB_STRMU
B:
[2-232]
M
K
T
I
K
V
K
N
K
T
E
G
S
K
V
A
F
R
M
L
E
E
E
I
-----
T
-----
F
-----
G
------
A
K
-----
T
L
G
L
A
T
G
S
T
P
L
E
L
Y
K
E
I
R
E
----
S
----
H
----
L
D
F
S
D
M
V
S
I
N
L
D
E
Y
V
G
L
S
A
D
D
K
Q
S
Y
A
Y
F
M
K
Q
N
L
F
A
A
K
--
P
F
--
K
K
S
--
Y
--
L
P
N
G
L
A
A
D
L
A
K
E
T
E
Y
Y
D
Q
-
I
L
-
A
Q
Y
-
P
-
I
D
L
Q
I
L
G
I
G
R
N
A
H
I
G
F
N
E
P
G
T
A
F
S
S
Q
T
H
L
V
D
L
T
P
S
T
I
-
A
A
N
S
R
F
F
E
-
K
-
A
-
E
D
V
P
K
Q
A
I
S
M
G
L
A
S
I
M
S
A
K
M
I
L
L
M
A
F
G
E
E
K
A
E
A
V
A
A
M
V
K
G
P
V
T
E
E
I
P
A
S
I
L
Q
T
H
P
K
V
I
L
I
V
D
E
K
A
G
A
------------------------------------
22
PsiBlast_CBE
95.81
54%
-84
- C5 -
2RI1
2
NAGB_STRMU
B:
[3-233]
M
K
T
I
K
V
K
N
K
T
E
G
S
K
V
A
F
R
M
L
E
E
E
I
-----
T
-----
F
-----
G
------
A
K
-----
T
L
G
L
A
T
G
S
T
P
L
E
L
Y
K
E
I
R
E
----
S
----
H
----
L
D
F
S
D
M
V
S
I
N
L
D
E
Y
V
G
L
S
A
D
D
K
Q
S
Y
A
Y
F
M
K
Q
N
L
F
A
A
K
--
P
F
--
K
K
S
--
Y
--
L
P
N
G
L
A
A
D
L
A
K
E
T
E
Y
Y
D
Q
-
I
L
-
A
Q
Y
-
P
-
I
D
L
Q
I
L
G
I
G
R
N
A
H
I
G
F
N
E
P
G
T
A
F
S
S
Q
T
H
L
V
D
L
T
P
S
T
I
-
A
A
N
S
R
F
F
E
-
K
-
A
-
E
D
V
P
K
Q
A
I
S
M
G
L
A
S
I
M
S
A
K
M
I
L
L
M
A
F
G
E
E
K
A
E
A
V
A
A
M
V
K
G
P
V
T
E
E
I
P
A
S
I
L
Q
T
H
P
K
V
I
L
I
V
D
E
K
A
G
A
------------------------------------
2
PsiBlast_PDB
95.21
54%
-83
- C5 -
2RI1
2
NAGB_STRMU
A:
[3-233]
M
K
T
I
K
V
K
N
K
T
E
G
S
K
V
A
F
R
M
L
E
E
E
I
-----
T
-----
F
-----
G
------
A
K
-----
T
L
G
L
A
T
G
S
T
P
L
E
L
Y
K
E
I
R
E
----
S
----
H
----
L
D
F
S
D
M
V
S
I
N
L
D
E
Y
V
G
L
S
A
D
D
K
Q
S
Y
A
Y
F
M
K
Q
N
L
F
A
A
K
--
P
F
--
K
K
S
--
Y
--
L
P
N
G
L
A
A
D
L
A
K
E
T
E
Y
Y
D
Q
-
I
L
-
A
Q
Y
-
P
-
I
D
L
Q
I
L
G
I
G
R
N
A
H
I
G
F
N
E
P
G
T
A
F
S
S
Q
T
H
L
V
D
L
T
P
S
T
I
-
A
A
N
S
R
F
F
E
-
K
-
A
-
E
D
V
P
K
Q
A
I
S
M
G
L
A
S
I
M
S
A
K
M
I
L
L
M
A
F
G
E
E
K
A
E
A
V
A
A
M
V
K
G
P
V
T
E
E
I
P
A
S
I
L
Q
T
H
P
K
V
I
L
I
V
D
E
K
A
G
A
------------------------------------
54
HHSearch
92.88
51%
-87
- C5 -
2RI0
1
NAGB_STRMU
A:
[2-234]
M
K
T
I
K
V
K
N
K
T
E
G
S
K
V
A
F
R
M
L
E
E
E
I
-----
T
-----
F
-----------
G
A
K
-----
T
L
G
L
A
T
G
S
T
P
L
E
L
Y
K
E
I
R
E
----
S
----
H
----
L
D
F
S
D
M
V
S
I
N
L
D
E
Y
V
G
L
S
A
D
D
K
Q
S
Y
A
Y
F
M
K
Q
N
L
F
A
A
K
PF
K
K
--
S
Y
L
--
P
--
N
G
L
A
-
A
D
L
A
K
-
E
T
E
Y
Y
D
Q
-
I
L
A
Q
-
Y
-
P
-
I
D
L
Q
I
L
G
I
G
R
N
A
H
I
G
F
N
E
P
G
T
A
F
S
S
Q
T
H
L
V
D
L
T
P
S
T
I
A
A
N
-
S
R
F
F
E
-
K
-
A
-
E
D
V
P
K
Q
A
I
S
M
G
L
A
S
I
M
S
A
K
M
I
L
L
M
A
F
G
E
E
K
A
E
A
V
A
A
M
V
K
G
P
V
T
E
E
I
P
A
S
I
L
Q
T
H
P
K
V
I
L
I
V
D
E
K
A
G
A
G
I
----------------------------------
55
HHSearch
90.19
48%
-76
- C5 -
2BKX
1
NAGB_BACSU
A:
[1-241]
M
K
V
M
E
C
Q
T
Y
E
E
L
S
Q
I
A
A
R
I
T
A
D
T
I
-----
K
-----
E
-----
K
-----
P
D
A
-----
V
L
G
L
A
T
G
G
T
P
E
G
T
Y
R
Q
L
I
R
----
L
H
Q
T
E
N
----
L
S
F
Q
N
I
T
T
V
N
L
D
E
Y
A
G
L
S
S
D
D
P
N
S
Y
H
F
Y
M
N
D
R
F
F
Q
H
I
DS
K
P
--
S
R
H
--
F
--
I
P
N
G
N
A
D
D
L
E
A
E
C
R
R
Y
E
Q
-
L
V
D
S
L
G
-
D
-
T
D
I
Q
L
L
G
I
G
R
N
G
H
I
G
F
N
E
P
G
T
S
F
K
S
R
T
H
V
V
T
L
N
E
Q
T
R
-
Q
A
N
A
R
Y
F
P
-
S
-
I
-
D
S
V
P
K
K
A
L
T
M
G
I
Q
T
I
L
S
S
K
R
I
L
L
L
I
S
G
K
S
K
A
E
A
V
R
K
L
L
E
G
N
I
S
E
D
F
P
A
S
A
L
H
L
H
S
D
V
T
V
L
I
D
R
E
A
A
S
L
R
----------------------------------
57
HHSearch
86.56
38%
-76
- C5 -
1NE7
4
GNPI1_HUMAN
A:
[1-247]
M
K
L
I
I
L
E
H
Y
S
Q
A
S
E
W
A
A
K
Y
I
R
N
R
I
-----
I
-----
Q
F
NPGP
E
-----
K
Y
F
-----
T
L
G
L
P
T
G
S
T
P
L
G
C
Y
K
K
L
I
E
Y
Y
K
N
G
----
D
----
L
S
F
K
Y
V
K
T
F
N
M
D
E
Y
V
G
L
P
R
D
H
P
E
S
Y
H
S
F
M
W
N
N
F
F
K
H
I
DI
H
P
--
E
N
T
--
H
--
I
L
D
G
N
A
V
D
L
Q
A
E
C
D
A
F
E
E
-
K
I
K
A
A
G
-
G
-
I
E
L
F
V
G
G
I
G
P
D
G
H
I
A
F
N
E
P
G
S
S
L
V
S
R
T
R
V
K
T
L
A
M
D
T
I
-
L
A
N
A
R
F
F
D
-
G
-
E
L
T
K
V
P
T
M
A
L
T
V
G
V
G
T
V
M
D
A
R
E
V
M
I
L
I
T
G
A
H
K
A
F
A
L
Y
K
A
I
E
E
G
V
N
H
M
W
T
V
S
A
F
Q
Q
H
P
R
T
V
F
V
C
D
E
D
A
T
L
E
L
----------------------------------
44
Fugue
86.02
37%
-78
- C5 -
1NE7
4
GNPI1_HUMAN
A:
[1-281]
M
K
L
I
I
L
E
H
Y
S
Q
A
S
E
W
A
A
K
Y
I
R
N
R
I
-----
I
-----
Q
-----
F
-----
N
P
G
PE
K
Y
F
T
L
G
L
P
T
G
S
T
P
L
G
C
Y
K
K
L
I
E
----
Y
----
Y
K
N
GD
L
S
F
K
Y
V
K
T
F
N
M
D
E
Y
V
G
L
P
R
D
H
P
E
S
Y
H
S
F
M
W
N
N
F
F
K
H
I
--
D
I
--
H
P
E
N
T
H
--
I
L
D
G
N
A
V
D
L
Q
A
E
C
D
A
F
E
E
-
K
I
-
K
A
A
-
G
G
I
E
L
F
V
G
G
I
G
P
D
G
H
I
A
F
N
E
P
G
S
S
L
V
S
R
T
R
V
K
T
L
A
M
D
T
I
-
L
A
N
A
R
F
F
D
G
E
-
L
-
T
K
V
P
T
M
A
L
T
V
G
V
G
T
V
M
D
A
R
E
V
M
I
L
I
T
G
A
H
K
A
F
A
L
Y
K
A
I
E
E
G
V
N
H
M
W
T
V
S
A
F
Q
Q
H
P
R
T
V
F
V
C
D
E
D
A
T
L
E
L
K
V
K
T
V
K
Y
F
K
G
L
M
LVHNKLVDPLYSIKEKETEKSQ
24
PsiBlast_CBE
85.86
52%
-86
- C5 -
2BKV
1
NAGB_BACSU
B:
[32-240]
--------------------------------------------------------
L
G
L
A
T
G
G
T
P
E
G
T
Y
R
Q
L
I
R
LHQT
E
----
N
----
L
S
F
Q
N
I
T
T
V
N
L
D
E
Y
A
G
L
S
S
D
D
P
N
S
Y
H
F
Y
M
N
D
R
F
F
Q
H
I
--
D
S
--
K
P
S
RH
F
--
I
P
N
G
N
A
D
D
L
E
A
E
C
R
R
Y
E
Q
-
L
V
D
S
L
G
-
D
-
T
D
I
Q
L
L
G
I
G
R
N
G
H
I
G
F
N
E
P
G
T
S
F
K
S
R
T
H
V
V
T
L
N
E
Q
T
R
-
Q
A
N
A
R
Y
F
P
-
S
-
I
-
D
S
V
P
K
K
A
L
T
M
G
I
Q
T
I
L
S
S
K
R
I
L
L
L
I
S
G
K
S
K
A
E
A
V
R
K
L
L
E
G
N
I
S
E
D
F
P
A
S
A
L
H
L
H
S
D
V
T
V
L
I
D
R
E
A
A
S
L
-----------------------------------
3
PsiBlast_PDB
85.65
52%
-81
- C5 -
2BKV
1
NAGB_BACSU
A:
[32-240]
--------------------------------------------------------
L
G
L
A
T
G
G
T
P
E
G
T
Y
R
Q
L
I
R
L
H
Q
T
E
----
N
----
L
S
F
Q
N
I
T
T
V
N
L
D
E
Y
A
G
L
S
S
D
D
P
N
S
Y
H
F
Y
M
N
D
R
F
F
Q
H
I
--
D
S
--
K
P
S
RH
F
--
I
P
N
G
N
A
D
D
L
E
A
E
C
R
R
Y
E
Q
-
L
V
D
S
L
G
-
D
-
T
D
I
Q
L
L
G
I
G
R
N
G
H
I
G
F
N
E
P
G
T
S
F
K
S
R
T
H
V
V
T
L
N
E
Q
T
R
-
Q
A
N
A
R
Y
F
P
-
S
-
I
-
D
S
V
P
K
K
A
L
T
M
G
I
Q
T
I
L
S
S
K
R
I
L
L
L
I
S
G
K
S
K
A
E
A
V
R
K
L
L
E
G
N
I
S
E
D
F
P
A
S
A
L
H
L
H
S
D
V
T
V
L
I
D
R
E
A
A
S
L
-----------------------------------
56
HHSearch
85.38
37%
-74
- C5 -
3HN6
1
NAGB_BORBU
A:
[22-268]
M
R
L
I
I
R
P
T
Y
E
D
I
S
K
W
A
A
N
H
V
A
Q
K
I
-----
N
E
F
SPT
K
-----
E
-----
N
P
F
-----
I
L
G
L
P
T
G
S
S
P
I
G
M
Y
K
N
L
I
E
----
L
N
K
N
K
K
----
I
S
F
Q
N
V
I
T
F
N
M
D
E
Y
I
G
I
E
E
N
H
P
E
S
Y
H
S
F
M
W
N
N
F
F
S
H
I
DI
K
K
--
E
N
I
--
N
--
I
L
N
G
N
A
S
N
L
K
K
E
C
E
E
Y
E
K
-
K
I
K
S
F
G
-
G
-
I
M
L
F
V
G
G
I
G
P
D
G
H
I
A
F
N
E
P
G
S
S
L
T
S
R
T
R
I
K
T
L
T
Q
D
T
I
-
I
A
N
S
R
F
F
E
-
G
-
D
V
N
K
V
P
K
N
A
L
T
V
G
I
G
T
I
M
D
S
Q
E
V
L
I
I
V
N
G
H
N
K
A
R
A
L
K
H
A
I
E
K
G
V
N
H
M
W
T
I
S
A
L
Q
L
H
K
N
A
I
I
V
S
D
K
N
A
T
Y
E
L
----------------------------------
4
PsiBlast_PDB
85.20
52%
-81
- C5 -
2BKX
1
NAGB_BACSU
A:
[32-240]
--------------------------------------------------------
L
G
L
A
T
G
G
T
P
E
G
T
Y
R
Q
L
I
R
L
H
Q
T
E
----
N
----
L
S
F
Q
N
I
T
T
V
N
L
D
E
Y
A
G
L
S
S
D
D
P
N
S
Y
H
F
Y
M
N
D
R
F
F
Q
H
I
--
D
S
--
K
P
S
R
H
F
--
I
P
N
G
N
A
D
D
L
E
A
E
C
R
R
Y
E
Q
-
L
V
D
S
L
G
-
D
-
T
D
I
Q
L
L
G
I
G
R
N
G
H
I
G
F
N
E
P
G
T
S
F
K
S
R
T
H
V
V
T
L
N
E
Q
T
R
-
Q
A
N
A
R
Y
F
P
-
S
-
I
-
D
S
V
P
K
K
A
L
T
M
G
I
Q
T
I
L
S
S
K
R
I
L
L
L
I
S
G
K
S
K
A
E
A
V
R
K
L
L
E
G
N
I
S
E
D
F
P
A
S
A
L
H
L
H
S
D
V
T
V
L
I
D
R
E
A
A
S
L
-----------------------------------
37
PsiBlast_CBE
84.98
36%
-75
- C5 -
1NE7
4
GNPI1_HUMAN
D:
[1-243]
M
K
L
I
I
L
E
H
Y
S
Q
A
S
E
W
A
A
K
Y
I
R
N
R
I
-----
I
-----
Q
-----
F
NPGPE
K
Y
F
-----
T
L
G
L
P
T
G
S
T
P
L
G
C
Y
K
K
L
I
E
YYKN
G
----
D
----
L
S
F
K
Y
V
K
T
F
N
M
D
E
Y
V
G
L
P
R
D
H
P
E
S
Y
H
S
F
M
W
N
N
F
F
K
H
I
--
D
I
HP
E
N
T
--
H
--
I
L
D
G
N
A
V
D
L
Q
A
E
C
D
A
F
E
E
K
I
K
-
A
A
G
-
G
-
I
E
L
F
V
G
G
I
G
P
D
G
H
I
A
F
N
E
P
G
S
S
L
V
S
R
T
R
V
K
T
L
A
M
D
T
I
-
L
A
N
A
R
F
F
D
-
G
-
E
L
T
K
V
P
T
M
A
L
T
V
G
V
G
T
V
M
D
A
R
E
V
M
I
L
I
T
G
A
H
K
A
F
A
L
Y
K
A
I
E
E
G
V
N
H
M
W
T
V
S
A
F
Q
Q
H
P
R
T
V
F
V
C
D
E
D
A
--------------------------------------
43
Fugue
84.80
36%
-76
- C5 -
1DEA
2
NAGB_ECOLI
A:
[1-266]
M
R
L
I
P
L
T
T
A
E
Q
V
G
K
W
A
A
R
H
I
V
N
R
I
-----
N
-----
A
F
KPTA
D
-----
R
P
F
-----
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
----
M
----
H
K
A
GQ
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
--
D
I
--
P
A
E
N
I
N
--
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
-
K
I
-
R
S
Y
G
K
-
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
R
-
V
A
N
S
R
F
F
D
-
N
D
V
-
N
Q
V
P
K
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
G
C
V
N
H
M
W
T
I
S
C
L
Q
L
H
P
K
A
I
M
V
C
D
E
P
S
T
M
E
L
K
V
K
T
L
R
Y
F
N
E
L
E
A
ENIKGL---------------
36
PsiBlast_CBE
84.53
36%
-74
- C5 -
1NE7
4
GNPI1_HUMAN
E:
[1-243]
M
K
L
I
I
L
E
H
Y
S
Q
A
S
E
W
A
A
K
Y
I
R
N
R
I
-----
I
-----
Q
-----
F
NPGPE
K
Y
F
-----
T
L
G
L
P
T
G
S
T
P
L
G
C
Y
K
K
L
I
E
YYKN
G
----
D
----
L
S
F
K
Y
V
K
T
F
N
M
D
E
Y
V
G
L
P
R
D
H
P
E
S
Y
H
S
F
M
W
N
N
F
F
K
H
I
--
D
I
HP
E
N
T
--
H
--
I
L
D
G
N
A
V
D
L
Q
A
E
C
D
A
F
E
E
K
I
K
-
A
A
G
-
G
-
I
E
L
F
V
G
G
I
G
P
D
G
H
I
A
F
N
E
P
G
S
S
L
V
S
R
T
R
V
K
T
L
A
M
D
T
I
-
L
A
N
A
R
F
F
D
-
G
-
E
L
T
K
V
P
T
M
A
L
T
V
G
V
G
T
V
M
D
A
R
E
V
M
I
L
I
T
G
A
H
K
A
F
A
L
Y
K
A
I
E
E
G
V
N
H
M
W
T
V
S
A
F
Q
Q
H
P
R
T
V
F
V
C
D
E
D
A
--------------------------------------
38
PsiBlast_CBE
84.40
36%
-75
- C5 -
1NE7
4
GNPI1_HUMAN
C:
[1-243]
M
K
L
I
I
L
E
H
Y
S
Q
A
S
E
W
A
A
K
Y
I
R
N
R
I
-----
I
-----
Q
-----
F
NPGPE
K
Y
F
-----
T
L
G
L
P
T
G
S
T
P
L
G
C
Y
K
K
L
I
E
YYKN
G
----
D
----
L
S
F
K
Y
V
K
T
F
N
M
D
E
Y
V
G
L
P
R
D
H
P
E
S
Y
H
S
F
M
W
N
N
F
F
K
H
I
--
D
I
HP
E
N
T
--
H
--
I
L
D
G
N
A
V
D
L
Q
A
E
C
D
A
F
E
E
K
I
K
-
A
A
G
-
G
-
I
E
L
F
V
G
G
I
G
P
D
G
H
I
A
F
N
E
P
G
S
S
L
V
S
R
T
R
V
K
T
L
A
M
D
T
I
-
L
A
N
A
R
F
F
D
-
G
-
E
L
T
K
V
P
T
M
A
L
T
V
G
V
G
T
V
M
D
A
R
E
V
M
I
L
I
T
G
A
H
K
A
F
A
L
Y
K
A
I
E
E
G
V
N
H
M
W
T
V
S
A
F
Q
Q
H
P
R
T
V
F
V
C
D
E
D
A
--------------------------------------
53
HHSearch
84.35
38%
-74
* C5 *
1FS5
2
NAGB_ECOLI
A:
[1-247]
M
R
L
I
P
L
T
T
A
E
Q
V
G
K
W
A
A
R
H
I
V
N
R
I
N
A
F
KP
T
-----
A
-----
D
-----
R
P
F
-----
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
----
Q
----
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
DI
P
A
--
E
N
I
--
N
--
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
-
K
I
R
S
Y
G
-
K
-
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
R
-
V
A
N
S
R
F
F
D
-
N
-
D
V
N
Q
V
P
K
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
G
C
V
N
H
M
W
T
I
S
C
L
Q
L
H
P
K
A
I
M
V
C
D
E
P
S
T
M
E
L
----------------------------------
15
PsiBlast_PDB
84.19
36%
-74
- C5 -
1NE7
4
GNPI1_HUMAN
A:
[1-243]
M
K
L
I
I
L
E
H
Y
S
Q
A
S
E
W
A
A
K
Y
I
R
N
R
I
-----
I
-----
Q
-----
F
NPGPE
K
Y
F
-----
T
L
G
L
P
T
G
S
T
P
L
G
C
Y
K
K
L
I
E
Y
Y
K
N
G
----
D
----
L
S
F
K
Y
V
K
T
F
N
M
D
E
Y
V
G
L
P
R
D
H
P
E
S
Y
H
S
F
M
W
N
N
F
F
K
H
I
--
D
I
HP
E
N
T
--
H
--
I
L
D
G
N
A
V
D
L
Q
A
E
C
D
A
F
E
E
K
I
K
-
A
A
G
-
G
-
I
E
L
F
V
G
G
I
G
P
D
G
H
I
A
F
N
E
P
G
S
S
L
V
S
R
T
R
V
K
T
L
A
M
D
T
I
-
L
A
N
A
R
F
F
D
-
G
-
E
L
T
K
V
P
T
M
A
L
T
V
G
V
G
T
V
M
D
A
R
E
V
M
I
L
I
T
G
A
H
K
A
F
A
L
Y
K
A
I
E
E
G
V
N
H
M
W
T
V
S
A
F
Q
Q
H
P
R
T
V
F
V
C
D
E
D
A
--------------------------------------
23
PsiBlast_CBE
83.89
52%
-80
- C5 -
2BKX
1
NAGB_BACSU
B:
[32-240]
--------------------------------------------------------
L
G
L
A
T
G
G
T
P
E
G
T
Y
R
Q
L
I
R
LHQT
E
----
N
----
L
S
F
Q
N
I
T
T
V
N
L
D
E
Y
A
G
L
S
S
D
D
P
N
S
Y
H
F
Y
M
N
D
R
F
F
Q
H
I
--
D
S
--
K
P
S
RH
F
--
I
P
N
G
N
A
D
D
L
E
A
E
C
R
R
Y
E
Q
-
L
V
D
S
L
G
-
D
-
T
D
I
Q
L
L
G
I
G
R
N
G
H
I
G
F
N
E
P
G
T
S
F
K
S
R
T
H
V
V
T
L
N
E
Q
T
R
-
Q
A
N
A
R
Y
F
P
-
S
-
I
-
D
S
V
P
K
K
A
L
T
M
G
I
Q
T
I
L
S
S
K
R
I
L
L
L
I
S
G
K
S
K
A
E
A
V
R
K
L
L
E
G
N
I
S
E
D
F
P
A
S
A
L
H
L
H
S
D
V
T
V
L
I
D
R
E
A
A
S
L
-----------------------------------
39
PsiBlast_CBE
83.78
36%
-72
- C5 -
1NE7
3
GNPI1_HUMAN
B:
[1-243]
M
K
L
I
I
L
E
H
Y
S
Q
A
S
E
W
A
A
K
Y
I
R
N
R
I
-----
I
-----
Q
-----
F
NPGPE
K
Y
F
-----
T
L
G
L
P
T
G
S
T
P
L
G
C
Y
K
K
L
I
E
YYKN
G
----
D
----
L
S
F
K
Y
V
K
T
F
N
M
D
E
Y
V
G
L
P
R
D
H
P
E
S
Y
H
S
F
M
W
N
N
F
F
K
H
I
--
D
I
HP
E
N
T
--
H
--
I
L
D
G
N
A
V
D
L
Q
A
E
C
D
A
F
E
E
K
I
K
-
A
A
G
-
G
-
I
E
L
F
V
G
G
I
G
P
D
G
H
I
A
F
N
E
P
G
S
S
L
V
S
R
T
R
V
K
T
L
A
M
D
T
I
-
L
A
N
A
R
F
F
D
-
G
-
E
L
T
K
V
P
T
M
A
L
T
V
G
V
G
T
V
M
D
A
R
E
V
M
I
L
I
T
G
A
H
K
A
F
A
L
Y
K
A
I
E
E
G
V
N
H
M
W
T
V
S
A
F
Q
Q
H
P
R
T
V
F
V
C
D
E
D
A
--------------------------------------
28
PsiBlast_CBE
77.32
39%
-82
- C5 -
2WU1
1
NAGB_ECOLI
B:
[36-240]
-------------------------------------------------------
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
MHKA
G
----
Q
----
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
--
D
I
--
P
A
E
--
N
IN
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
-
S
Y
G
-
K
-
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
R
-
V
A
N
S
R
F
F
D
-
N
-
D
V
N
Q
V
P
K
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
G
C
V
N
H
M
W
T
I
S
C
L
Q
L
H
P
K
A
I
M
V
C
D
-----------------------------------------
5
PsiBlast_PDB
76.06
39%
-79
- C5 -
1HOR
1
NAGB_ECOLI
A:
[36-240]
-------------------------------------------------------
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
----
Q
----
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
--
D
I
--
P
A
E
--
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
-
S
Y
G
-
K
-
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
R
-
V
A
N
S
R
F
F
D
-
N
-
D
V
N
Q
V
P
K
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
G
C
V
N
H
M
W
T
I
S
C
L
Q
L
H
P
K
A
I
M
V
C
D
-----------------------------------------
14
PsiBlast_PDB
75.61
39%
-77
- C5 -
2WU1
1
NAGB_ECOLI
A:
[36-240]
-------------------------------------------------------
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
----
Q
----
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
--
D
I
--
P
A
E
--
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
-
S
Y
G
-
K
-
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
R
-
V
A
N
S
R
F
F
D
-
N
-
D
V
N
Q
V
P
K
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
G
C
V
N
H
M
W
T
I
S
C
L
Q
L
H
P
K
A
I
M
V
C
D
-----------------------------------------
30
PsiBlast_CBE
74.76
39%
-76
- C5 -
1HOR
1
NAGB_ECOLI
B:
[36-240]
-------------------------------------------------------
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
MHKA
G
----
Q
----
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
--
D
I
--
P
A
E
--
N
IN
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
-
S
Y
G
-
K
-
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
R
-
V
A
N
S
R
F
F
D
-
N
-
D
V
N
Q
V
P
K
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
G
C
V
N
H
M
W
T
I
S
C
L
Q
L
H
P
K
A
I
M
V
C
D
-----------------------------------------
33
PsiBlast_CBE
74.50
39%
-78
- C5 -
1FQO
2
NAGB_ECOLI
B:
[36-240]
-------------------------------------------------------
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
MHKA
G
----
Q
----
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
--
D
I
--
P
A
E
--
N
IN
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
-
S
Y
G
-
K
-
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
R
-
V
A
N
S
R
F
F
D
-
N
-
D
V
N
Q
V
P
K
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
G
C
V
N
H
M
W
T
I
S
C
L
Q
L
H
P
K
A
I
M
V
C
D
-----------------------------------------
11
PsiBlast_PDB
74.45
39%
-78
- C5 -
1FS5
1
NAGB_ECOLI
A:
[36-240]
-------------------------------------------------------
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
----
Q
----
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
--
D
I
--
P
A
E
--
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
-
S
Y
G
-
K
-
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
R
-
V
A
N
S
R
F
F
D
-
N
-
D
V
N
Q
V
P
K
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
G
C
V
N
H
M
W
T
I
S
C
L
Q
L
H
P
K
A
I
M
V
C
D
-----------------------------------------
9
PsiBlast_PDB
74.43
39%
-77
- C5 -
1FQO
2
NAGB_ECOLI
A:
[36-240]
-------------------------------------------------------
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
----
Q
----
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
--
D
I
--
P
A
E
--
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
-
S
Y
G
-
K
-
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
R
-
V
A
N
S
R
F
F
D
-
N
-
D
V
N
Q
V
P
K
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
G
C
V
N
H
M
W
T
I
S
C
L
Q
L
H
P
K
A
I
M
V
C
D
-----------------------------------------