@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2114: (2016-04-01 )
METVLQAKNVRKIYGSKGNVYTALENISIDIKEGEFTGIMGPSGAGKSTLLNVLSTIDKPTSGQIVISGQELENMNEQQMSTFRRDKLGFIFQDYNLLDTLTIRENIILPLALAKRPVKEMEEKLAIISEKFGITEILDKYPSEISGGQKQRTAASRAIITSPSLIFADEPTGALDSKSATNLLESLRDLNEQDKSTIMMVTHDAFAASFCKRILFIKDGELYTEIYRGTKTRKEFFQKILDVLAKLGGDSDDVI
Atome Classification :
(36 SA)
.........10........20........30........40........50........60........70..----.--.....80........90........100.......-110....---...120.......130....-...140---........150.......160.......170.......180.......190.......200..-.-.-...210.......220-----.-----..------....--230--.-......240---------........250...----------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
ME
T
V
L
Q
A
K
N
V
R
K
I
YGSKG
N
V
Y
T
A
L
E
N
I
S
I
D
I
KEG
E
F
T
G
IMGPSGA
G
K
S
T
L
L
N
V
L
S
T
IDKPTS
G
Q
I
V
I
S
G
Q
E
L
E
----N--M
N
E
Q
Q
M
S
T
F
R
R
DKL
G
F
I
F
QDYNL
L
D
T
L
T
IREN
I
I
L
-
P
L
A
L
AKR---
P
V
K
E
M
E
E
K
L
A
I
I
S
E
KF
G
I
T
E
-
I
L
D
KY----
P
S
EISGGQ
K
Q
RTAAS
R
A
I
ITSP
S
L
I
F
ADEPTGALDS
K
S
A
T
N
L
L
E
S
L
R
D
L
N
EQDK
S
T
I
M
M
V
T
H
D
-
A
-
F
-
A
A
S
F
C
K
R
I
L
F
IKDG
E
L
-----
Y
-----
T
E
------
I
Y
RG--T
K
T
--
R
-
K
E
F
F
Q
K
I
L
----------
D
V
L
A
K
LGGDSDDVI----------------------------------------------------------------------
92
HHSearch
92.24
41%
-89
- C1 -
3TIF
7
Y796_METJA
A:
[1-229]
---
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
----
D
--
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
-
P
L
I
F
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
----
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
-
N
-
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
-----
E
-----
R
E
------
E
K
L
----------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
91.32
42%
-89
- C1 -
1L2T
4
Y796_METJA
A:
[1-226]
---
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
----
D
--
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
-
P
L
I
F
K
Y
R
---
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
-
L
E
E
R
F
ANHK
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
-
N
-
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
-----
E
-----
R
E
-------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
89.30
42%
-87
- C1 -
1L2T
4
Y796_METJA
B:
[1-226]
---
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
----
D
--
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
-
P
L
I
F
K
Y
R
---
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
-
L
E
E
R
F
ANHK
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
-
N
-
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
-----
E
-----
R
E
-------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
89.12
42%
-83
- C1 -
1F3O
2
Y796_METJA
A:
[2-226]
----
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
----
D
--
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
-
P
L
I
F
K
Y
R
---
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
-
L
E
E
R
F
ANHK
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
E
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
-
N
-
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
-----
E
-----
R
E
-------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
88.88
41%
-87
- C1 -
3TIF
7
Y796_METJA
B:
[1-226]
---
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
----
D
--
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
-
P
L
I
F
K
Y
R
---
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
-
L
E
E
R
F
ANHK
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
-
N
-
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
-----
E
-----
R
E
-------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
88.38
41%
-86
- C1 -
3TIF
7
Y796_METJA
A:
[1-226]
---
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
N
----
D
--
L
D
D
D
E
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
-
P
L
I
F
K
Y
R
---
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
-
L
E
E
R
F
ANHK
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
-
I
-
N
-
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
-----
E
-----
R
E
-------------------------------------------------------------------------------------------------------------------------
96
Fugue
88.36
33%
-98
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
----
T
--
L
S
E
S
E
L
T
K
A
R
R
Q
-
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
-
P
L
E
L
D
N
T
---
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
-
K
H
D
S
Y
----
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
-
V
-
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
-----
I
EQDTV
S
E
------
V
F
S
H
PK
T
P
L
--
A
-
Q
K
F
I
Q
S
T
L
HLDIPEDYQE
R
L
Q
A
E
P
F
T
D
C
V
P
M
L
RLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV
89
HHSearch
87.37
41%
-87
- C1 -
2PCJ
-
LOLD_AQUAE
A:
[2-222]
-
A
E
I
L
R
A
E
N
I
K
K
V
I
R
G
----
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
----
Y
--
T
N
E
K
E
L
S
L
L
R
N
R
K
L
G
F
V
F
Q
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
V
-
P
M
L
K
M
G
K
---
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
-
K
L
S
R
K
----
P
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
E
-
G
G
T
S
I
V
M
V
T
H
E
-
R
-
E
-
L
A
E
L
T
H
R
T
L
E
M
K
D
G
K
V
-----
V
-----
G
E
------
I
T
-----------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
85.72
39%
-87
- C1 -
2PCJ
-
LOLD_AQUAE
A:
[2-223]
-
A
E
I
L
R
A
E
N
I
K
K
V
I
R
G
----
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
----
Y
--
T
N
E
K
E
L
S
L
L
R
N
R
K
L
G
F
V
F
Q
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
V
-
P
M
L
K
M
G
K
---
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
-
K
L
S
R
K
----
P
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
E
G
G
-
T
S
I
V
M
V
T
H
E
-
R
-
E
-
L
A
E
L
T
H
R
T
L
E
M
K
D
G
K
V
-----
V
-----
G
E
------
I
T
R
----------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
85.50
33%
-101
- C1 -
3TUI
1
METN_ECOLI
C:
[24-270]
---
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
----
T
--
L
S
E
S
E
L
T
K
A
R
R
-
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
-
P
L
E
L
D
N
T
---
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
-
K
H
D
S
Y
----
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
-
M
D
V
-
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
IEQDT
V
-----
S
E
------
V
F
S
H
--
P
K
T
PL
A
-
Q
K
F
I
Q
S
T
L
----------
H
L
----------------------------------------------------------------------------------
23
PsiBlast_CBE
85.23
39%
-88
- C1 -
2PCJ
1
LOLD_AQUAE
B:
[2-223]
-
A
E
I
L
R
A
E
N
I
K
K
V
I
R
G
----
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
----
Y
--
T
N
E
K
E
L
S
L
L
R
N
R
K
L
G
F
V
F
Q
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
V
-
P
M
L
K
M
G
K
---
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
-
K
L
S
R
K
----
P
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
E
G
G
-
T
S
I
V
M
V
T
H
E
-
R
-
E
-
L
A
E
L
T
H
R
T
L
E
M
K
D
G
K
V
-----
V
-----
G
E
------
I
T
R
----------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
85.19
33%
-103
- C1 -
3TUZ
1
METN_ECOLI
C:
[24-270]
---
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
----
T
--
L
S
E
S
E
L
T
K
A
R
R
-
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
-
P
L
E
L
D
N
T
---
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
-
K
H
D
S
Y
----
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
-
M
D
V
-
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
IEQDT
V
-----
S
E
------
V
F
S
H
--
P
K
T
PL
A
-
Q
K
F
I
Q
S
T
L
----------
H
L
----------------------------------------------------------------------------------
25
PsiBlast_CBE
84.61
33%
-97
- C1 -
3TUZ
1
METN_ECOLI
G:
[24-270]
---
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
----
T
--
L
S
E
S
E
L
T
K
A
R
R
-
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
-
P
L
E
L
D
N
T
---
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
-
K
H
D
S
Y
----
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
-
M
D
V
-
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
IEQDT
V
-----
S
E
------
V
F
S
H
--
P
K
T
PL
A
-
Q
K
F
I
Q
S
T
L
----------
H
L
----------------------------------------------------------------------------------
35
PsiBlast_CBE
84.09
35%
-96
- C1 -
4YMU
2
?
A:
[4-240]
---------
V
N
D
V
Y
K
N
F
G
S
L
-
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
----
N
GK
V
N
I
N
K
V
----
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
M
---
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
----
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
-----
V
-----
E
E
GT
P
E
E
I
F
Y
R
A
--
K
N
E
--
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
29
PsiBlast_CBE
84.02
33%
-99
- C1 -
3TUI
1
METN_ECOLI
D:
[24-270]
---
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
----
T
--
L
S
E
S
E
L
T
K
A
R
R
-
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
-
P
L
E
L
D
N
T
---
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
-
K
H
D
S
Y
----
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
-
M
D
V
-
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
IEQDT
V
-----
S
E
------
V
F
S
H
--
P
K
T
PL
A
-
Q
K
F
I
Q
S
T
L
----------
H
L
----------------------------------------------------------------------------------
13
PsiBlast_PDB
83.45
35%
-95
- C1 -
4YMS
-
?
J:
[4-240]
---------
V
N
D
V
Y
K
N
F
G
S
L
-
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
----
N
GK
V
N
I
N
K
V
----
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
M
---
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
----
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
-----
V
-----
E
E
GTPEEI
F
Y
R
A
--
K
N
E
--
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
24
PsiBlast_CBE
83.43
33%
-100
- C1 -
3TUZ
1
METN_ECOLI
H:
[24-270]
---
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
T
----
T
--
L
S
E
S
E
L
T
K
A
R
R
-
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
-
P
L
E
L
D
N
T
---
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
-
K
H
D
S
Y
----
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
-
M
D
V
-
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
IEQDT
V
-----
S
E
------
V
F
S
H
--
P
K
T
PL
A
-
Q
K
F
I
Q
S
T
L
----------
H
L
----------------------------------------------------------------------------------
15
PsiBlast_PDB
83.35
35%
-97
- C1 -
4YMU
2
?
J:
[4-240]
---------
V
N
D
V
Y
K
N
F
G
S
L
-
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
----
N
GK
V
N
I
N
K
V
----
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
M
---
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
----
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
-----
V
-----
E
E
GTPEEI
F
Y
R
A
--
K
N
E
--
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
5
PsiBlast_PDB
83.27
39%
-84
- C1 -
2PCL
12
LOLD_AQUAE
A:
[2-223]
-
A
E
I
L
R
A
E
N
I
K
K
V
I
R
G
----
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
----
Y
--
T
N
E
K
E
L
S
L
L
R
N
R
K
L
G
F
V
F
Q
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
V
-
P
M
L
K
M
G
K
---
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
-
K
L
S
R
K
----
P
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
E
G
G
-
T
S
I
V
M
V
T
H
E
-
R
-
E
-
L
A
E
L
T
H
R
T
L
E
M
K
D
G
K
V
-----
V
-----
G
E
------
I
T
R
----------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
83.21
35%
-93
- C1 -
4YMV
1
?
J:
[4-240]
---------
V
N
D
V
Y
K
N
F
G
S
L
-
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
----
N
GK
V
N
I
N
K
V
----
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
M
---
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
----
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
-----
V
-----
E
E
GTPEEI
F
Y
R
A
--
K
N
E
--
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
34
PsiBlast_CBE
83.19
35%
-93
- C1 -
4YMV
1
?
A:
[4-240]
---------
V
N
D
V
Y
K
N
F
G
S
L
-
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
N
----
N
GK
V
N
I
N
K
V
----
R
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
M
---
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
-
K
K
D
Q
Y
----
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
-----
V
-----
E
E
GT
P
E
E
I
F
Y
R
A
--
K
N
E
--
R
T
R
E
F
L
S
K
I
L
----------------------------------------------------------------------------------------------
11
PsiBlast_PDB
81.02
32%
-87
- C1 -
4U00
3
?
A:
[3-242]
--
P
I
I
R
I
R
N
L
H
K
W
F
G
P
----
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
--
L
S
----
V
--
K
D
D
R
A
L
R
E
I
R
R
E
-
V
G
M
V
F
Q
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
M
R
V
R
R
W
---
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
I
L
D
-
Q
A
R
K
Y
----
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
-
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
-----
V
-----
E
E
GR
P
E
E
I
F
T
R
P
--
K
E
E
--
R
T
R
S
F
L
Q
R
V
L
----------------------------------------------------------------------------------------------
18
PsiBlast_PDB
71.94
36%
-85
- C1 -
2D62
7
?
A:
[12-221]
------------
I
W
K
R
F
G
D
V
-
T
A
V
K
D
L
S
L
E
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
R
G
Q
I
Y
I
E
D
N
L
V
A
----
D
--
P
E
K
G
V
F
V
P
P
K
E
R
D
V
A
M
V
F
Q
S
Y
A
L
Y
P
H
M
T
V
Y
D
N
I
A
F
-
P
L
K
L
R
K
V
---
P
K
Q
E
I
D
K
R
V
R
E
V
A
E
M
L
G
L
T
E
-
L
L
N
R
K
----
P
R
E
L
S
G
G
Q
R
Q
R
V
A
L
G
R
A
I
I
R
R
P
K
V
F
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
K
M
R
A
E
L
K
K
L
Q
R
Q
L
G
V
T
T
I
Y
V
T
H
D
-
Q
-
V
E
A
M
T
M
G
D
R
I
A
V
M
N
K
G
E
L
--------------------------------------------------------------------------------------------------------------------------------------
56
PsiBlast_CBE
69.10
33%
-85
- C1 -
2OLJ
4
?
A:
[22-240]
----
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
-
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
AKDT
N
--
L
N
K
V
------
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
-----
I
-----
E
E
-------------------------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
68.76
33%
-78
- C1 -
2OLK
1
?
D:
[22-240]
----
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
-
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
AKDT
N
--
L
N
K
V
------
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
-----
I
-----
E
E
-------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
68.38
31%
-99
- C1 -
1VCI
1
?
A:
[13-237]
----
V
K
L
E
N
L
T
K
R
F
G
N
----
F
T
A
V
N
K
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
E
G
R
I
Y
F
G
D
R
D
V
T
----
Y
--
L
P
P
K
D
R
N
------
I
S
M
V
F
Q
------
H
M
T
V
Y
E
N
I
A
F
-
P
L
--
K
K
F
---
P
K
D
E
I
D
K
R
V
R
W
A
A
E
L
L
Q
I
E
E
-
L
L
N
R
Y
----
P
A
Q
L
S
G
G
Q
R
Q
R
V
A
V
A
R
A
I
V
V
E
P
D
V
L
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
A
M
R
A
E
I
K
K
L
Q
Q
K
L
K
V
T
T
I
Y
V
T
H
D
-
Q
-
V
E
A
M
T
M
G
D
R
I
A
V
M
N
R
G
Q
L
-----
L
Q
I
G
S
P
T
E
------
V
Y
-----------------------------------------------------------------------------------------------------------------
53
PsiBlast_CBE
68.33
33%
-78
- C1 -
2OLK
2
?
B:
[22-240]
----
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
-
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
AKDT
N
--
L
N
K
V
------
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
-----
I
-----
E
E
-------------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
67.55
33%
-77
- C1 -
2OLK
1
?
C:
[22-240]
----
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
-
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
AKDT
N
--
L
N
K
V
------
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
-----
I
-----
E
E
-------------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
67.45
33%
-78
- C1 -
2OLK
1
?
A:
[22-240]
----
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
-
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
AK
D
T
N
--
L
N
K
V
------
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
-----
I
-----
E
E
-------------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
66.64
33%
-78
- C1 -
3C41
3
?
K:
[1-219]
----
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
-
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
AKDT
N
--
L
N
K
V
------
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
-----
I
-----
E
E
-------------------------------------------------------------------------------------------------------------------------
43
PsiBlast_CBE
66.12
33%
-83
- C1 -
3C4J
4
?
B:
[22-240]
----
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
-
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
AKDT
N
--
L
N
K
V
------
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
-----
I
-----
E
E
-------------------------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
65.79
33%
-74
- C1 -
3C4J
3
?
A:
[22-240]
----
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
-
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
AKDT
N
--
L
N
K
V
------
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
-----
I
-----
E
E
-------------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
65.47
33%
-75
- C1 -
3C41
3
?
J:
[1-219]
----
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
-
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
AKDT
N
--
L
N
K
V
------
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
-----
I
-----
E
E
-------------------------------------------------------------------------------------------------------------------------
45
PsiBlast_CBE
64.50
33%
-75
- C1 -
2Q0H
4
?
B:
[22-240]
----
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
-
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
AKDT
N
--
L
N
K
V
------
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
-----
I
-----
E
E
-------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
64.01
33%
-76
- C1 -
2Q0H
4
?
A:
[23-240]
-----
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
-
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
AKDT
N
--
L
N
K
V
------
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
-----
I
-----
E
E
-------------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
63.23
33%
-72
- C1 -
2OLJ
3
?
B:
[22-240]
----
L
Q
M
I
D
V
H
Q
L
K
K
S
F
G
S
L
-
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
K
AKDT
N
--
L
N
K
V
------
R
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
---
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
-
K
A
H
A
Y
----
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
-
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
-
F
-
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
-----
I
-----
E
E
-------------------------------------------------------------------------------------------------------------------------