@TOME V2.3
(Nov 2016)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0914: (2015-12-04 )
MIKINFPILDEPLVLSNATILTIEDVSVYSSLVKHFYQYDVDEHLKLFDDKQKSLKATELMLVTDILGYDVNSAPILKLIHGDLENQFNEKPEVKSMVEKLAATITELIAFECLENELDLEYDEITILELIKALGVKIETQSDTIFEKCFEIIQVYHYLTKKNLLVFVNSGAYLTKDEVIKLCEYINLMQKSVLFLEPRRLYDLPQYVIDKDYFLIGENMV
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10..------......20..---......30........40..------.......50.......----.60........-----70........80.--------......---------------------.90........100.......110.--......120.......130.......140.......-----.150.......160....--------------.--------------..---------------------------170-------.........180.......190---------------........200......-.210.......220---------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
K
INFPILDEP
L
------
V
LSN
A
T
I
L
T
I
---
E
D
V
S
V
Y
S
S
L
V
K
H
F
Y
QY
D
-
V
D
------
E
H
L
K
L
F
D
D
K
Q
KSLKAT----
E
L
M
L
V
T
D
I
LGY-----DVN
S
A
P
I
L
K
L
I
H
G
--------
D
L
E
N
QF---------------------NEKP
E
V
K
S
M
V
E
K
L
A
A
T
I
T
E
L
I
A
F
E
C
--
L
E
N
ELDLE
Y
D
E
I
T
I
L
E
L
I
K
ALG
V
K
I
ETQ-S
D
T
I
F
E
K
-----
C
F
E
I
I
Q
V
Y
H
Y
L
TKK
N
L
L
V
--------------
F
--------------VN---------------------------S---------GAYL
T
K
D
E
V
I
K
L
C
E
Y
I
N
L
M
Q
K
----------------
S
V
L
FL
E
P
R
R
LYDL
P
Q
Y
V
-IDK
D
Y
F
L
IGENMV----------------------------------------
18
HHSearch
98.17
100%
-168
- C6 -
3QHQ
4
CSN2_STRAG
A:
[1-221]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
K
I
N
F
P
I
L
D
E
P
L
------
V
L
S
N
A
T
I
L
T
I
---
E
D
V
S
V
Y
S
S
L
V
K
H
F
Y
Q
Y
D
-
V
D
------
E
H
L
K
L
F
D
D
K
Q
K
S
L
K
A
T
----
E
L
M
L
V
T
D
I
L
G
Y
-----
D
V
N
S
A
P
I
L
K
L
I
H
G
--------
D
L
E
N
Q
F
---------------------
N
E
K
P
E
V
K
S
M
V
E
K
L
A
A
T
I
T
E
L
I
A
F
E
C
--
L
E
N
E
L
D
L
E
Y
D
E
I
T
I
L
E
L
I
K
A
L
G
V
K
I
E
T
Q
-
S
D
T
I
F
E
K
-----
C
F
E
I
I
Q
V
Y
H
Y
L
T
K
K
N
L
L
V
--------------
F
--------------
V
N
---------------------------
S
---------
G
A
Y
L
T
K
D
E
V
I
K
L
C
E
Y
I
N
L
M
Q
K
----------------
S
V
L
F
L
E
P
R
R
L
Y
D
L
P
Q
Y
V
-
I
D
K
D
Y
F
L
I
G
E
N
M
V
----------------------------------------
1
PsiBlast_PDB
97.97
99%
-168
- C6 -
3QHQ
4
CSN2_STRAG
A:
[1-221]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
K
I
N
F
P
I
L
D
E
P
L
------
V
L
S
N
A
T
I
L
T
I
---
E
D
V
S
V
Y
S
S
L
V
K
H
F
Y
Q
Y
D
-
V
D
------
E
H
L
K
L
F
D
D
K
Q
K
S
L
K
A
T
----
E
L
M
L
V
T
D
I
L
G
Y
-----
D
V
N
S
A
P
I
L
K
L
I
H
G
--------
D
L
E
N
Q
F
---------------------
N
E
K
P
E
V
K
S
M
V
E
K
L
A
A
T
I
T
E
L
I
A
F
E
C
--
L
E
N
E
L
D
L
E
Y
D
E
I
T
I
L
E
L
I
K
A
L
G
V
K
I
E
T
Q
-
S
D
T
I
F
E
K
-----
C
F
E
I
I
Q
V
Y
H
Y
L
T
K
K
N
L
L
V
--------------
F
--------------
V
N
---------------------------
S
---------
G
A
Y
L
T
K
D
E
V
I
K
L
C
E
Y
I
N
L
M
Q
K
----------------
S
V
L
F
L
E
P
R
R
L
Y
D
L
P
Q
Y
V
-
I
D
K
D
Y
F
L
I
G
E
N
M
V
----------------------------------------
10
PsiBlast_CBE
97.90
99%
-175
- C6 -
3QHQ
6
CSN2_STRAG
B:
[1-216]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
K
I
N
F
P
I
L
D
E
P
L
------
V
L
S
N
A
T
I
L
T
I
---
E
D
V
S
V
Y
S
S
L
V
K
H
F
Y
Q
Y
D
-
V
D
------
E
-----
D
D
K
Q
K
S
L
K
A
T
----
E
L
M
L
V
T
D
I
L
G
Y
-----
D
V
N
S
A
P
I
L
K
L
I
H
G
--------
D
L
E
N
Q
F
---------------------
N
E
K
P
E
V
K
S
M
V
E
K
L
A
A
T
I
T
E
L
I
A
F
E
C
--
L
E
N
E
L
D
L
E
Y
D
E
I
T
I
L
E
L
I
K
A
L
G
V
K
I
E
T
Q
-
S
D
T
I
F
E
K
-----
C
F
E
I
I
Q
V
Y
H
Y
L
T
K
K
N
L
L
V
--------------
F
--------------
V
N
---------------------------
S
---------
G
A
Y
L
T
K
D
E
V
I
K
L
C
E
Y
I
N
L
M
Q
K
----------------
S
V
L
F
L
E
P
R
R
L
Y
D
L
P
Q
Y
V
-
I
D
K
D
Y
F
L
I
---------------------------------------------
3
PsiBlast_PDB
88.67
69%
-169
- C6 -
3TOC
4
CSN2_STRP1
A:
[7-223]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
F
S
L
L
D
E
P
I
------
P
L
R
G
G
T
I
L
V
L
---
E
D
V
C
V
F
S
K
I
V
Q
Y
C
Y
Q
Y
E
---------
S
E
L
K
F
F
---
M
K
T
I
K
E
S
----
E
I
M
L
V
T
D
I
L
G
F
-----
D
V
N
S
S
T
I
L
K
L
I
H
A
--------
D
L
E
S
Q
F
---------------------
N
E
K
P
E
V
K
S
M
I
D
K
L
V
A
T
I
T
E
L
I
V
F
E
C
--
L
E
N
E
L
D
L
E
Y
D
E
I
T
I
L
E
L
I
K
S
L
G
V
K
V
E
T
Q
-
S
D
T
I
F
E
K
-----
C
L
E
I
L
Q
I
F
K
Y
L
T
K
K
K
L
L
I
--------------
F
--------------
V
N
---------------------------
S
---------
G
A
F
L
T
K
D
E
V
A
S
L
Q
E
Y
I
S
L
T
N
L
----------------
T
V
L
F
L
E
P
R
E
L
Y
D
F
P
Q
Y
I
-
L
D
----
L
I
T
K
N
M
-----------------------------------------
2
PsiBlast_PDB
87.44
70%
-161
- C6 -
3V7F
2
CSN2_STRP1
A:
[5-223]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
L
N
F
S
L
L
D
E
P
I
------
P
L
R
G
G
T
I
L
V
L
---
E
D
V
C
V
F
S
K
I
V
Q
Y
C
Y
Q
Y
E
-
E
D
------
S
E
L
K
F
F
D
--
M
K
T
I
K
E
S
----
E
I
M
L
V
T
D
I
L
G
F
-----
D
V
N
S
S
T
I
L
K
L
I
H
A
--------
D
L
E
S
Q
F
---------------------
N
E
K
P
E
V
K
S
M
I
D
K
L
V
A
T
I
T
E
L
I
V
F
E
C
--
L
E
N
E
L
D
L
E
Y
D
E
I
T
I
L
E
L
I
K
S
L
G
V
K
V
E
T
Q
-
S
D
T
I
F
E
K
-----
C
L
E
I
L
Q
I
F
K
Y
L
T
K
K
K
L
L
I
--------------
F
--------------
V
N
---------------------------
S
---------
G
A
F
L
T
K
D
E
V
A
S
L
Q
E
Y
I
S
L
T
N
L
----------------
T
V
L
F
L
E
P
R
E
L
Y
D
F
P
Q
Y
I
-
L
D
E
D
Y
F
L
I
T
K
N
M
-----------------------------------------
11
PsiBlast_CBE
86.04
70%
-163
- C6 -
3V7F
1
CSN2_STRP1
B:
[5-223]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
L
N
F
S
L
L
D
E
P
I
------
P
L
R
G
G
T
I
L
V
L
---
E
D
V
C
V
F
S
K
I
V
Q
Y
C
Y
Q
Y
E
-
E
D
------
S
E
L
K
F
F
D
H
K
M
K
T
I
K
E
S
----
E
I
M
L
V
T
D
I
L
G
F
-----
D
V
N
S
S
T
I
L
K
L
I
H
A
--------
D
L
E
S
Q
F
---------------------
N
E
K
P
E
V
K
S
M
I
D
K
L
V
A
T
I
T
E
L
I
V
F
E
C
--
L
E
N
E
L
D
L
E
Y
D
E
I
T
I
L
E
L
I
K
S
L
G
V
K
V
E
T
Q
-
S
D
T
I
F
E
K
-----
C
L
E
I
L
Q
I
F
K
Y
L
T
K
K
K
L
L
I
--------------
F
--------------
V
N
---------------------------
S
---------
G
A
F
L
T
K
D
E
V
A
S
L
Q
E
Y
I
S
L
T
N
L
----------------
T
V
L
F
L
E
P
R
E
L
Y
D
F
P
Q
Y
I
-
L
D
E
D
Y
F
L
I
T
K
N
M
-----------------------------------------
17
PsiBlast_CBE
83.41
58%
-165
- C6 -
3S5U
4
CSN2_ENTFL
B:
[3-215]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
N
F
S
----
P
I
------
E
I
E
K
A
T
F
L
T
I
---
K
D
V
Q
S
F
A
H
L
V
K
L
I
Y
Q
Y
D
----------------------
K
P
T
----
E
L
F
V
V
T
D
I
L
G
Y
-----
D
V
N
S
A
A
T
L
K
L
I
Y
G
--------
D
L
E
A
Q
L
---------------------
N
D
K
P
E
V
K
S
M
I
E
K
L
T
G
T
I
S
Q
L
I
G
Y
E
L
--
L
E
H
E
M
D
L
E
E
D
G
I
I
V
Q
E
L
F
K
A
L
G
I
K
I
E
T
T
-
S
D
T
I
F
E
K
-----
V
M
E
I
T
Q
V
H
R
Y
L
S
K
K
K
L
L
I
--------------
F
--------------
I
N
---------------------------
A
---------
C
T
Y
L
T
E
D
E
V
Q
Q
V
V
E
Y
I
S
L
N
N
V
----------------
D
V
L
F
L
E
Q
R
V
V
Q
N
R
F
Q
Y
I
-
L
D
E
N
F
Y
L
S
Y
E
K
A
-----------------------------------------
14
PsiBlast_CBE
82.29
58%
-146
- C6 -
3S5U
4
CSN2_ENTFL
E:
[3-215]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
N
F
S
L
L
E
E
P
I
------
E
I
E
K
A
T
F
L
T
I
---
K
D
V
Q
S
F
A
H
L
V
K
L
I
Y
Q
Y
D
-
G
E
------
N
E
L
K
L
----
Q
K
G
L
K
P
T
----
E
L
F
V
V
T
D
I
L
G
Y
-----
D
V
N
S
A
A
T
L
K
L
I
Y
G
--------
D
L
E
A
Q
L
---------------------
N
D
K
P
E
V
K
S
M
I
E
K
L
T
G
T
I
S
Q
L
I
G
Y
E
L
--
L
E
H
E
M
D
L
E
E
D
G
I
I
V
Q
E
L
F
K
A
L
G
I
K
I
E
T
T
-
S
D
T
I
F
E
K
-----
V
M
E
I
T
Q
V
H
R
Y
L
S
K
K
K
L
L
I
--------------
F
--------------
I
N
---------------------------
A
---------
C
T
Y
L
T
E
D
E
V
Q
Q
V
V
E
Y
I
S
L
N
N
V
----------------
D
V
L
F
L
E
Q
R
V
V
Q
N
R
F
Q
Y
I
-
L
D
E
N
F
Y
L
S
Y
E
K
------------------------------------------
16
PsiBlast_CBE
82.06
58%
-149
- C6 -
3S5U
4
CSN2_ENTFL
C:
[3-215]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
N
F
S
--
E
E
P
I
------
E
I
E
K
A
T
F
L
T
I
---
K
D
V
Q
S
F
A
H
L
V
K
L
I
Y
Q
Y
D
-
G
E
-------
E
L
K
L
-----
K
G
L
K
P
T
----
E
L
F
V
V
T
D
I
L
G
Y
-----
D
V
N
S
A
A
T
L
K
L
I
Y
G
--------
D
L
E
A
Q
L
---------------------
N
D
K
P
E
V
K
S
M
I
E
K
L
T
G
T
I
S
Q
L
I
G
Y
E
L
--
L
E
H
E
M
D
L
E
E
D
G
I
I
V
Q
E
L
F
K
A
L
G
I
K
I
E
T
T
-
S
D
T
I
F
E
K
-----
V
M
E
I
T
Q
V
H
R
Y
L
S
K
K
K
L
L
I
--------------
F
--------------
I
N
---------------------------
A
---------
C
T
Y
L
T
E
D
E
V
Q
Q
V
V
E
Y
I
S
L
N
N
V
----------------
D
V
L
F
L
E
Q
R
V
V
Q
N
R
F
Q
Y
I
-
L
D
E
N
F
Y
L
S
Y
E
K
A
-----------------------------------------
28
Fugue
81.36
57%
-137
- C6 -
3S5U
4
CSN2_ENTFL
A:
[3-220]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
N
F
S
L
L
E
E
P
I
------
E
I
E
K
A
T
F
L
T
I
---
K
D
V
Q
S
F
A
H
L
V
K
L
I
Y
Q
Y
D
-
N
E
------
L
K
L
Q
------
K
G
L
K
P
T
----
E
L
F
V
V
T
D
I
L
G
Y
-----
D
V
N
S
A
A
T
L
K
L
I
Y
G
--------
D
L
E
A
Q
L
---------------------
N
D
K
P
E
V
K
S
M
I
E
K
L
T
G
T
I
S
Q
L
I
G
Y
E
L
--
L
E
H
E
M
D
L
E
E
D
G
I
I
V
Q
E
L
F
K
A
L
G
I
K
I
E
T
T
-
S
D
T
I
F
E
K
-----
V
M
E
I
T
Q
V
H
R
Y
L
S
K
K
K
L
L
I
--------------
F
--------------
I
N
---------------------------
A
---------
C
T
Y
L
T
E
D
E
V
Q
Q
V
V
E
Y
I
S
L
N
N
V
----------------
D
V
L
F
L
E
Q
R
V
V
Q
N
R
F
Q
Y
I
-
L
D
E
N
F
Y
L
S
Y
E
K
A
-----------------------------------------
12
PsiBlast_CBE
81.36
58%
-147
- C6 -
3S5U
4
CSN2_ENTFL
G:
[3-215]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
N
F
---
E
E
P
I
------
E
I
E
K
A
T
F
L
T
I
---
K
D
V
Q
S
F
A
H
L
V
K
L
I
Y
Q
Y
D
----------
E
L
K
L
F
D
A
Q
--
G
L
K
P
T
----
E
L
F
V
V
T
D
I
L
G
Y
-----
D
V
N
S
A
A
T
L
K
L
I
Y
G
--------
D
L
E
A
Q
L
---------------------
N
D
K
P
E
V
K
S
M
I
E
K
L
T
G
T
I
S
Q
L
I
G
Y
E
L
--
L
E
H
E
M
D
L
E
E
D
G
I
I
V
Q
E
L
F
K
A
L
G
I
K
I
E
T
T
-
S
D
T
I
F
E
K
-----
V
M
E
I
T
Q
V
H
R
Y
L
S
K
K
K
L
L
I
--------------
F
--------------
I
N
---------------------------
A
---------
C
T
Y
L
T
E
D
E
V
Q
Q
V
V
E
Y
I
S
L
N
N
V
----------------
D
V
L
F
L
E
Q
R
V
V
Q
N
R
F
Q
Y
I
-
L
D
E
N
F
Y
L
S
Y
E
K
------------------------------------------
4
PsiBlast_PDB
79.95
58%
-146
- C6 -
3S5U
4
CSN2_ENTFL
A:
[3-215]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
N
F
S
L
L
E
E
P
I
------
E
I
E
K
A
T
F
L
T
I
---
K
D
V
Q
S
F
A
H
L
V
K
L
I
Y
Q
Y
D
---------
N
E
L
K
L
----
Q
K
G
L
K
P
T
----
E
L
F
V
V
T
D
I
L
G
Y
-----
D
V
N
S
A
A
T
L
K
L
I
Y
G
--------
D
L
E
A
Q
L
---------------------
N
D
K
P
E
V
K
S
M
I
E
K
L
T
G
T
I
S
Q
L
I
G
Y
E
L
--
L
E
H
E
M
D
L
E
E
D
G
I
I
V
Q
E
L
F
K
A
L
G
I
K
I
E
T
T
-
S
D
T
I
F
E
K
-----
V
M
E
I
T
Q
V
H
R
Y
L
S
K
K
K
L
L
I
--------------
F
--------------
I
N
---------------------------
A
---------
C
T
Y
L
T
E
D
E
V
Q
Q
V
V
E
Y
I
S
L
N
N
V
----------------
D
V
L
F
L
E
Q
R
V
V
Q
N
R
F
Q
Y
I
-
L
D
E
N
F
Y
L
S
Y
E
K
A
-----------------------------------------
19
HHSearch
79.11
56%
-137
- C6 -
3S5U
4
CSN2_ENTFL
A:
[3-219]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
N
F
S
L
L
E
E
P
I
------
E
I
E
K
A
T
F
L
T
I
---
K
D
V
Q
S
F
A
H
L
V
K
L
I
-
Y
Q
Y
D--------
N
E
L
K
L
----
Q
K
G
L
K
P
T
----
E
L
F
V
V
T
D
I
L
G
Y
-----
D
V
N
S
A
A
T
L
K
L
I
Y
G
--------
D
L
E
A
Q
L
---------------------
N
D
K
P
E
V
K
S
M
I
E
K
L
T
G
T
I
S
Q
L
I
G
Y
E
L
--
L
E
H
E
M
D
L
E
E
D
G
I
I
V
Q
E
L
F
K
A
L
G
I
K
I
E
T
T
-
S
D
T
I
F
E
K
-----
V
M
E
I
T
Q
V
H
R
Y
L
S
K
K
K
L
L
I
--------------
F
--------------
I
N
---------------------------
A
---------
C
T
Y
L
T
E
D
E
V
Q
Q
V
V
E
Y
I
S
L
N
N
V
----------------
D
V
L
F
L
E
Q
R
V
V
Q
N
R
F
Q
Y
I
-
L
D
E
N
F
Y
L
S
Y
E
K
A
-----------------------------------------
13
PsiBlast_CBE
78.81
58%
-146
- C6 -
3S5U
4
CSN2_ENTFL
F:
[3-215]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
N
F
S
----
P
I
------
E
I
E
K
A
T
F
L
T
I
---
K
D
V
Q
S
F
A
H
L
V
K
L
I
Y
Q
Y
D
-
G
E
------
N
E
L
K
L
F
----
K
G
L
K
P
T
----
E
L
F
V
V
T
D
I
L
G
Y
-----
D
V
N
S
A
A
T
L
K
L
I
Y
G
--------
D
L
E
A
Q
L
---------------------
N
D
K
P
E
V
K
S
M
I
E
K
L
T
G
T
I
S
Q
L
I
G
Y
E
L
--
L
E
H
E
M
D
L
E
E
D
G
I
I
V
Q
E
L
F
K
A
L
G
I
K
I
E
T
T
-
S
D
T
I
F
E
K
-----
V
M
E
I
T
Q
V
H
R
Y
L
S
K
K
K
L
L
I
--------------
F
--------------
I
N
---------------------------
A
---------
C
T
Y
L
T
E
D
E
V
Q
Q
V
V
E
Y
I
S
L
N
N
V
----------------
D
V
L
F
L
E
Q
R
V
V
Q
N
R
F
Q
Y
I
-
L
D
E
N
F
Y
L
S
Y
E
K
A
-----------------------------------------
15
PsiBlast_CBE
76.73
58%
-146
- C6 -
3S5U
4
CSN2_ENTFL
D:
[3-215]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
N
F
S
L
L
E
E
P
I
------
E
I
E
K
A
T
F
L
T
I
---
K
D
V
Q
S
F
A
H
L
V
K
L
I
Y
Q
Y
D
-
G
E
------
N
E
L
K
L
F
-----
G
L
K
P
T
----
E
L
F
V
V
T
D
I
L
G
Y
-----
D
V
N
S
A
A
T
L
K
L
I
Y
G
--------
D
L
E
A
Q
L
---------------------
N
D
K
P
E
V
K
S
M
I
E
K
L
T
G
T
I
S
Q
L
I
G
Y
E
L
--
L
E
H
E
M
D
L
E
E
D
G
I
I
V
Q
E
L
F
K
A
L
G
I
K
I
E
T
T
-
S
D
T
I
F
E
K
-----
V
M
E
I
T
Q
V
H
R
Y
L
S
K
K
K
L
L
I
--------------
F
--------------
I
N
---------------------------
A
---------
C
T
Y
L
T
E
D
E
V
Q
Q
V
V
E
Y
I
S
L
N
N
V
----------------
D
V
L
F
L
E
Q
R
V
V
Q
N
R
F
Q
Y
I
-
L
D
E
N
F
Y
L
S
Y
E
K
------------------------------------------
24
HHSearch
39.03
16%
-107
- C6 -
2GJX
-
HEXA_HUMAN
A:
[143-233]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
R
F
P
H
R
G
L
L
L
D
T
S
R
H
Y
L
P
L
S
S
-----
I
L
D
T
L
D
V
M
A
Y
N
K
L
N
V
F
H
W
--------------
H
LVDDPSFPYESFTF
P
E
---------------------------
L
M
R
K
GSYNPV
T
H
I
Y
T
A
Q
D
V
K
E
V
I
E
Y
A
R
L
R
G
I
----------------
R
V
L
A
E
F
D
T
P
G
H
T
L
S
W
G
P
-
G
I
P
G
L
L
T
P
C
Y
S
G
S
----------------------------------------
32
Fugue
38.71
18%
-98
- C3 -
3UGM
-
PTHX1_XANOP
A:
[169-1048]
KPKVRELVAHIVALSQHPAALGTVAVTYQHIITALAT
H
E
D
I
V
G
V
G
KQWSG
A
R
A
L
E
A
L
L
T
D
A
G
E
L
RGPPLQLDT
G
Q
L
V
K
I
A
K
R
GG
V
T
A
M
E
A
V
H
A
SRNALTPLNLT
P
A
Q
V
V
A
I
A
SNNG
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
HGLTPA
Q
V
V
A
I
A
SHDG
G
K
Q
A
L
E
T
M
Q
R
L
L
P
V
L
C
Q
A
HGLP
P
D
Q
V
V
A
I
A
SNIG
G
K
Q
A
L
E
T
V
Q
R
L
L
PVLCQAHGLT
P
D
Q
V
V
A
I
A
SHGG
G
K
Q
A
L
E
T
V
Q
R
LLPVLCQAHGLT
P
D
Q
V
V
A
I
A
SHDG
G
K
Q
A
L
E
T
V
Q
R
LLPVLCQAHGLT
P
D
Q
V
V
A
I
A
SNGG
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
AHGLT
P
D
Q
V
V
A
I
A
S
NGG
K
Q
A
L
E
T
V
Q
R
LLPVLCQAHGLT
P
D
Q
V
V
A
I
A
SHDG
G
K
Q
A
L
E
T
V
Q
R
LL
P
V
L
C
Q
THGLT
P
A
Q
V
V
A
I
A
SHDG
G
K
Q
A
L
E
T
V
Q
Q
L
L
P
V
L
C
Q
AHGLT
P
D
Q
V
V
A
I
A
SNIG
G
K
Q
A
L
A
T
V
Q
R
LLPVLCQAHGLTPDQV
V
A
I
A
S
N
GGG
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
AHGLT
P
D
Q
V
V
A
I
A
SNGG
G
K
Q
A
L
E
T
V
Q
R
LLPVLCQAHGLTQVQVVAIASNIGGKQA
L
E
T
V
Q
R
L
LPVLCQA
H
G
L
T
P
A
Q
V
V
A
I
A
SHDG
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
AHGLT
P
D
Q
V
V
A
IASNGG
G
K
Q
A
L
E
T
V
Q
R
LLPGLT
Q
E
Q
V
V
A
I
A
SNNGG
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
A
H
------
G
L
T
P
D
Q
V
V
A
I
A
SN
G
G
G
K
Q
A
L
E
T
V
Q
R
L
L
P
V
L
-
C
Q
------
A
H
---------
G
L
T
P
A
----
Q
V
V
A
I
A
S
N
I
G
---------
G
K
Q
A
L
E
T
V
Q
R
--------
L
L
P
V
L
C
---------------------
Q
D
H
G
L
T
L
A
Q
V
V
A
I
A
S
N
I
G
G
K
Q
A
L
E
T
--
V
Q
R
L
L
P
V
L
C
Q
G
L
T
Q
D
Q
V
V
A
I
A
--------
S
N
I
G
G
K
Q
-----
A
L
E
T
V
Q
R
L
--------
L
P
--------------
V
--------------
L
C
---------------------------
Q
---------
D
H
G
L
T
P
D
Q
V
V
A
I
A
S
N
I
G
--
G
K
----------------
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
------
D
H
G
L
T
L
D
Q
V
V
A
I
A
S
N
GGK
Q
A
L
E
T
V
Q
R
L
L
P
V
L
C
Q
DHGLTPDQVVAIASNSG
21
HHSearch
38.07
18%
-100
* C6 *
1NOW
1
HEXB_HUMAN
A:
[149-238]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
R
F
S
H
R
G
I
L
I
D
T
S
R
H
Y
L
P
V
K
I
-----
I
L
K
T
L
D
A
M
A
F
N
K
F
N
V
L
H
W
HIVDDQSFPYQSIT
F
--------------
P
E
---------------------------
L
S
N
KGSYSL-
S
H
V
Y
T
P
N
D
V
R
M
V
I
E
Y
A
R
L
R
G
I
----------------
R
V
L
P
E
F
D
T
P
G
H
T
L
S
W
G
K
-
G
Q
K
D
L
L
T
P
C
Y
S
L
D
----------------------------------------
23
HHSearch
37.61
11%
-83
- C6 -
3GH5
1
?
A:
[181-273]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
E
Y
R
G
L
M
L
D
V
A
R
H
F
F
T
V
D
E
-----
V
K
R
Q
I
D
L
A
S
Q
Y
K
I
N
K
F
H
M
--------------
H
--------------
L
S
DDQGWRIEIKSWPDLIEIGSKGQVGG
G
P
---------
G
G
Y
Y
T
Q
E
Q
F
K
D
I
V
S
Y
A
A
E
R
Y
I
----------------
E
V
I
P
E
I
D
M
P
G
H
T
N
A
A
L
A
-
S
Y
G
E
L
N
P
D
G
K
R
K
A
----------------------------------------
34
Fugue
37.16
18%
-81
* C7 *
4RKS
4
MV3K_THEAC
A:
[21-337]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TYR
S
I
G
S
T
A
Y
P
T
I
G
VVL
L
G
G
I
A
N
P
V
T
R
T
P
L
H
T
S
A
G
I
A
Y
S
D
S
C
G
S
I
R
---
S
E
T
R
I
Y
A
D
E
A
T
H
I
Y
F
N
G
-
T
E
STDDNR
S
V
R
R
V
L
D
R
Y
S
S
V
F
E
E
A
FGTK
T
V
S
Y
S
S
Q
N
F
G
I
LSGSS
D
A
G
A
A
S
I
G
A
A
I
L
G
L
KPDLD
P
H
D
V
E
N
D
L
RAVSES
A
G
R
S
L
F
G
G
L
T
I
T
W
S
D
G
F
H
A
Y
T
E
K
I
L
D
P
E
A
F
S
G
Y
S
I
V
A
F
A
F
DY
Q
R
N
P
S
D
V
I
H
Q
N
I
V
R
S
D
L
Y
P
A
R
K
K
H
A
D
E
H
-
A
H
M
I
K
E
Y
A
K
T
ND
I
K
G
I
F
D
L
A
Q
E
D
T
E
E
Y
H
S
I
--------------
L
--------------
R
G
---------------------------
V
---------
G
V
N
V
I
R
E
N
M
Q
K
L
I
S
Y
L
K
L
I
R
K
D
Y
W
N
A
Y
I
V
T
GGS
N
V
Y
V
A
V
E
S
E
N
A
D
R
L
F
S
I
E
N
T
F
G
S
K
K
K
M
L
R
I
V
G
G
A
W
H
R
RPE-----------------------------------