@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu22660: (2016-07-05 )
MLEKIIKQKKEEVKTLVLPVEQPFEKRSFKEALASPNRFIGLIAEVKKASPSKGLIKEDFVPVQIAKDYEAAKADAISVLTDTPFFQGENSYLSDVKRAVSIPVLRKDFIDSLQVEESRRIGADAILLIGEVLDPLHLHELYLEAGEKGMDVLVEVHDASTLEQILKVFTPDILGVNNRNLKTFETSVKQTEQIASLVPKESLLVSESGIGSLEHLTFVNEHGARAVLIGESLMRQTSQRKAIHALFRE
Atome Classification :
(23 SA)
---.........10......--.--.20....-------.-----...30.....--...40........50........60........70........80........90........100.......-110.......-.120.......130.......140......-.150.....-..160.......170.......180.......190.......---200--........210........220.......230.......240.......----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---
M
L
E
K
I
I
K
Q
K
K
E
E
V
K
T
L
V
--L--PVEQ
P
F
E
-------
K
-----
R
S
F
K
E
A
LAS
P
--
N
R
F
I
G
L
I
A
E
V
KKASPSKGLIKED
F
V
P
V
Q
I
AKDYEAAKA
D
A
I
S
V
LTDTPFFQGE
N
S
Y
L
S
D
V
K
R
A
VSI
P
V
L
R
K
D
F
-
I
-
D
S
L
Q
V
E
E
S-RRIG
A
D
A
I
L
L
I
G
E
VL
D
P
L
H
L
H
E
L
Y
L
E
AGEK-G
M
D
V
L
V
E
VH-
D
A
S
T
L
E
Q
I
L
K
V
FT
P
D
ILGVNNRN
L
K
T
F
E
T
S
V
K
Q
T
E
Q
I
A
S
LVP---KE---
S
L
L
VSESGI-GSL
E
H
L
T
F
VNEHG
A
R
A
V
L
I
G
E
S
L
M
R
Q
T
S
Q
R
K
A
I
H
A
L
FRE----
21
PsiBlast_CBE
74.11
48%
-32
- C1 -
3TSM
4
TRPC_BRUA2
B:
[59-266]
------------------------------------------------------------
F
A
L
I
A
E
I
K
K
A
S
P
S
K
G
L
I
R
P
D
F
D
P
P
A
L
A
K
A
Y
E
E
G
G
A
A
C
L
S
V
L
T
D
T
P
S
F
Q
G
A
P
E
F
L
T
A
A
R
Q
A
C
S
L
P
A
L
R
K
D
F
-
L
F
D
P
Y
Q
V
Y
E
A
-
R
S
W
G
A
D
C
I
L
I
I
M
A
S
V
D
D
D
L
A
K
E
L
E
D
T
A
F
A
L
-
G
M
D
A
L
I
E
V
H
-
D
E
A
E
M
E
R
A
L
K
L
-
S
S
R
L
L
G
V
N
N
R
N
L
R
S
F
E
V
N
L
A
V
S
E
R
L
A
K
M
A
P
---
S
D
---
R
L
L
V
G
E
S
G
I
-
F
T
H
E
D
C
L
R
L
E
K
S
G
I
G
T
F
L
I
G
E
S
L
M
R
Q
H
D
V
A
A
A
T
R
A
L
L
------
1
PsiBlast_PDB
74.10
48%
-33
- C1 -
3TSM
1
TRPC_BRUA2
A:
[59-266]
------------------------------------------------------------
F
A
L
I
A
E
I
K
K
A
S
P
S
K
G
L
I
R
P
D
F
D
P
P
A
L
A
K
A
Y
E
E
G
G
A
A
C
L
S
V
L
T
D
T
P
S
F
Q
G
A
P
E
F
L
T
A
A
R
Q
A
C
S
L
P
A
L
R
K
D
F
-
L
F
D
P
Y
Q
V
Y
E
A
-
R
S
W
G
A
D
C
I
L
I
I
M
A
S
V
D
D
D
L
A
K
E
L
E
D
T
A
F
A
L
-
G
M
D
A
L
I
E
V
H
-
D
E
A
E
M
E
R
A
L
K
L
-
S
S
R
L
L
G
V
N
N
R
N
L
R
S
F
E
V
N
L
A
V
S
E
R
L
A
K
M
A
P
---
S
D
---
R
L
L
V
G
E
S
G
I
-
F
T
H
E
D
C
L
R
L
E
K
S
G
I
G
T
F
L
I
G
E
S
L
M
R
Q
H
D
V
A
A
A
T
R
A
L
L
------
42
HHSearch
72.93
45%
27
- C1 -
3TSM
3
TRPC_BRUA2
A:
[9-267]
---
I
L
R
K
I
E
A
Y
K
R
E
E
I
A
A
A
K
A
R
L
--
A
L
D
E
L
K
A
R
T
R
D
QSA
P
-----
R
G
F
L
K
A
L
E
A
K
R
A
A
G
Q
F
A
L
I
A
E
I
K
K
A
S
P
S
K
G
L
I
R
P
D
F
D
P
P
A
L
A
K
A
Y
E
E
G
G
A
A
C
L
S
V
L
T
D
T
P
S
F
Q
G
A
P
E
F
L
T
A
A
R
Q
A
C
S
L
P
A
L
R
K
D
F
-
L
F
D
P
Y
Q
V
Y
E
A
-
R
S
W
G
A
D
C
I
L
I
I
M
A
S
V
D
D
D
L
A
K
E
L
E
D
T
A
F
A
L
-
G
M
D
A
L
I
E
V
H
-
D
E
A
E
M
E
R
A
L
K
-
L
S
S
R
L
L
G
V
N
N
R
N
L
R
S
F
E
V
N
L
A
V
S
E
R
L
A
K
M
A
P
---
S
D
---
R
L
L
V
G
E
S
G
I
-
F
T
H
E
D
C
L
R
L
E
K
S
G
I
G
T
F
L
I
G
E
S
L
M
R
Q
H
D
V
A
A
A
T
R
A
L
L
T
-----
4
PsiBlast_PDB
71.23
39%
-11
- C1 -
1VC4
6
?
A:
[11-252]
---
V
L
G
E
I
A
R
K
R
A
S
E
V
A
P
Y
P
--
L
--
P
--
E
P
P
S
-------
V
-----
P
S
F
K
E
A
L
L
R
P
--
G
--
L
S
V
I
A
E
V
K
R
Q
S
P
S
E
G
L
I
R
E
-
V
D
P
V
E
A
A
L
A
Y
A
R
G
G
A
R
A
V
S
V
L
T
E
P
H
R
F
G
G
S
L
L
D
L
K
R
V
R
E
A
V
D
L
P
L
L
R
K
D
F
V
V
-
D
P
F
M
L
E
E
A
-
R
A
F
G
A
S
A
A
L
L
I
V
A
L
L
G
--
E
L
T
G
A
Y
L
E
E
A
R
R
L
G
L
E
A
L
V
E
V
H
-
T
E
R
E
L
E
I
A
L
E
A
G
A
-
E
V
L
G
I
N
N
R
D
L
A
T
L
H
I
N
L
E
T
A
P
R
L
G
R
L
A
R
---
K
R
GFG
G
V
L
V
A
E
S
G
Y
-
S
R
K
E
E
L
K
A
L
-
E
G
L
F
D
A
V
L
I
G
T
S
L
M
R
A
P
D
L
E
A
A
L
R
E
L
-------
45
HHSearch
69.82
39%
-20
* C1 *
1VC4
6
?
A:
[11-253]
---
V
L
G
E
I
A
R
K
R
A
S
E
V
A
P
Y
P
------
L
P
E
P
P
S
-------
V
-----
P
S
F
K
E
A
L
L
----
R
P
G
L
S
V
I
A
E
V
K
R
Q
S
P
S
E
G
L
I
R
E
-
V
D
P
V
E
A
A
L
A
Y
A
R
G
G
A
R
A
V
S
V
L
T
E
P
H
R
F
G
G
S
L
L
D
L
K
R
V
R
E
A
V
D
L
P
L
L
R
K
D
F
-
V
V
D
P
F
M
L
E
E
A
-
R
A
F
G
A
S
A
A
L
L
I
V
A
L
L
G
E
-
L
T
G
A
Y
L
E
E
A
R
R
L
-
G
L
E
A
L
V
E
V
H
-
T
E
R
E
L
E
I
A
L
E
-
A
G
A
E
V
L
G
I
N
N
R
D
L
A
T
L
H
I
N
L
E
T
A
P
R
L
G
R
L
A
R
K
R
G
F
G
---
G
V
L
V
A
E
S
G
Y
-
S
R
K
E
E
L
K
A
L
E
G
-
L
F
D
A
V
L
I
G
T
S
L
M
R
A
P
D
L
E
A
A
L
R
E
L
V
------
23
PsiBlast_CBE
67.97
39%
-6
- C1 -
1VC4
8
?
B:
[11-252]
---
V
L
G
E
I
A
R
K
R
A
S
E
V
A
P
Y
P
--
L
--
P
--
E
P
P
S
-------
V
-----
P
S
F
K
E
A
L
L
R
P
--
G
--
L
S
V
I
A
E
V
K
R
Q
S
P
S
E
G
L
I
R
E
-
V
D
P
V
E
A
A
L
A
Y
A
R
G
G
A
R
A
V
S
V
L
T
E
P
H
R
F
G
G
S
L
L
D
L
K
R
V
R
E
A
V
D
L
P
L
L
R
K
D
F
V
V
-
D
P
F
M
L
E
E
A
-
R
A
F
G
A
S
A
A
L
L
I
V
A
L
L
G
--
E
L
T
G
A
Y
L
E
E
A
R
R
L
G
L
E
A
L
V
E
V
H
-
T
E
R
E
L
E
I
A
L
E
A
G
A
-
E
V
L
G
I
N
N
R
D
L
A
T
L
H
I
N
L
E
T
A
P
R
L
G
R
L
A
R
---
K
R
GFG
G
V
L
V
A
E
S
G
Y
-
S
R
K
E
E
L
K
A
L
-
E
G
L
F
D
A
V
L
I
G
T
S
L
M
R
A
P
D
L
E
A
A
L
R
E
L
-------
7
PsiBlast_PDB
67.57
37%
-49
- C1 -
3T78
5
TRPC_MYCTU
A:
[52-259]
------------------------------------------------------------
I
G
V
I
A
E
V
K
R
A
S
P
S
A
G
A
L
A
T
I
A
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
S
I
P
V
L
R
K
D
F
V
V
-
Q
P
Y
Q
I
H
E
A
-
R
A
H
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
D
R
T
E
S
L
-
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
A
G
A
-
K
V
I
G
V
N
A
R
D
L
M
T
L
--
D
R
D
C
F
A
R
I
A
P
G
L
P
---
S
S
---
V
I
R
I
A
E
S
G
V
-
R
G
T
A
D
L
L
A
Y
A
G
A
G
A
D
A
V
L
V
G
E
G
L
V
T
S
G
D
P
R
A
A
V
A
D
L
V
------
2
PsiBlast_PDB
67.46
38%
-48
- C1 -
1I4N
1
TRPC_THEMA
A:
[31-241]
-----------------------------------------------
F
L
E
V
L
S
G
K
--
E
R
-
V
K
I
I
A
E
F
K
K
A
S
P
S
A
G
D
I
N
A
D
A
S
L
E
D
F
I
R
M
Y
D
E
L
-
A
D
A
I
S
I
L
T
E
K
H
Y
F
K
G
D
P
A
F
V
R
A
A
R
N
L
T
C
R
P
I
L
A
K
D
F
Y
I
-
D
T
V
Q
V
K
L
A
-
S
S
V
G
A
D
A
I
L
I
I
A
R
I
L
T
A
E
Q
I
K
E
I
Y
E
A
A
E
E
L
-
G
M
D
S
L
V
E
V
H
-
S
R
E
D
L
E
K
V
F
S
V
I
R
P
K
I
I
G
I
N
T
R
D
L
D
T
F
E
I
K
K
N
V
L
W
E
L
L
P
L
V
P
---
D
D
---
T
V
V
V
A
E
S
G
I
-
K
D
P
R
E
L
K
D
L
R
-
G
K
V
N
A
V
L
V
G
T
S
I
M
K
A
E
N
P
R
R
------------
22
PsiBlast_CBE
65.79
38%
-44
- C1 -
1I4N
1
TRPC_THEMA
B:
[31-241]
-----------------------------------------------
F
L
E
V
L
S
G
K
--
E
R
-
V
K
I
I
A
E
F
K
K
A
S
P
S
A
G
D
I
N
A
D
A
S
L
E
D
F
I
R
M
Y
D
E
L
-
A
D
A
I
S
I
L
T
E
K
H
Y
F
K
G
D
P
A
F
V
R
A
A
R
N
L
T
C
R
P
I
L
A
K
D
F
Y
I
-
D
T
V
Q
V
K
L
A
-
S
S
V
G
A
D
A
I
L
I
I
A
R
I
L
T
A
E
Q
I
K
E
I
Y
E
A
A
E
E
L
-
G
M
D
S
L
V
E
V
H
-
S
R
E
D
L
E
K
V
F
S
V
I
R
P
K
I
I
G
I
N
T
R
D
L
D
T
F
E
I
K
K
N
V
L
W
E
L
L
P
L
V
P
---
D
D
---
T
V
V
V
A
E
S
G
I
-
K
D
P
R
E
L
K
D
L
R
-
G
K
V
N
A
V
L
V
G
T
S
I
M
K
A
E
N
P
R
R
------------
63
Fugue
65.18
35%
-16
- C1 -
1PII
1
?
?:
[1-255]
MQT
V
L
A
K
I
V
A
D
K
A
I
W
V
E
A
R
K
--
Q
Q
Q
P
L
A
S
F
Q
N
-------
E
VQPST
R
H
F
Y
D
A
L
Q
G
A
--
R
--
T
A
F
I
L
E
C
K
K
A
S
P
S
K
G
V
I
R
D
D
F
D
P
A
R
I
A
A
I
Y
K
H
-
Y
A
S
A
I
S
V
L
T
D
E
K
Y
F
Q
G
S
F
N
F
L
P
I
V
S
Q
I
A
P
Q
P
I
L
C
K
D
F
I
I
-
D
P
Y
Q
I
Y
L
A
R
-
Y
Y
Q
A
D
A
C
L
L
M
L
S
V
L
D
D
D
Q
Y
R
Q
L
A
A
V
A
H
S
L
-
E
M
G
V
L
T
E
V
S
N--
E
E
E
Q
E
R
A
I
A
L
G
A
K
V
V
G
I
N
N
R
D
L
R
D
L
S
I
D
L
N
R
T
R
E
L
A
P
K
L
G
---
H
N
---
V
T
V
I
S
E
S
G
I
-
N
T
Y
A
Q
V
R
E
L
S
H
-
F
A
N
G
F
L
I
G
S
A
L
M
A
H
D
----
D
L
H
A
A
V
R
R
V
L
LG
6
PsiBlast_PDB
63.99
37%
-45
- C1 -
3T55
3
TRPC_MYCTU
A:
[52-259]
------------------------------------------------------------
I
G
V
I
A
E
V
K
R
A
S
P
S
A
G
A
L
A
T
I
A
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
S
I
P
V
L
R
K
D
F
V
V
-
Q
P
Y
Q
I
H
E
A
-
R
A
H
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
D
R
T
E
S
L
-
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
A
G
A
-
K
V
I
G
V
N
A
R
D
L
M
T
L
D
V
D
R
D
C
F
A
R
I
A
P
G
L
P
---
S
S
---
V
I
R
I
A
E
S
G
V
-
R
G
T
A
D
L
L
A
Y
A
G
A
G
A
D
A
V
L
V
G
E
G
L
V
T
S
G
D
P
R
A
A
V
A
D
L
V
------
43
HHSearch
63.92
35%
18
- C1 -
1PII
1
TRPC_ECOLI
A:
[4-252]
---
V
L
A
K
I
V
A
D
K
A
I
W
V
E
A
R
K
Q
Q
Q
--
P
L
A
S
F
Q
N
EVQPS--
T
-----
R
H
F
Y
D
A
L
Q
----
G
A
R
T
A
F
I
L
E
C
K
K
A
S
P
S
K
G
V
I
R
D
D
F
D
P
A
R
I
A
A
I
Y
K
-
H
Y
A
S
A
I
S
V
L
T
D
E
K
Y
F
Q
G
S
F
N
F
L
P
I
V
S
Q
I
A
P
Q
P
I
L
C
K
D
F
-
I
I
D
P
Y
Q
I
Y
L
A
-
R
Y
Y
Q
A
D
A
C
L
L
M
L
S
V
L
D
D
D
Q
Y
R
Q
L
A
A
V
A
H
S
L
-
E
M
G
V
L
T
E
V
S
-
N
E
E
E
Q
E
R
A
I
A
-
L
G
A
K
V
V
G
I
N
N
R
D
L
R
D
L
S
I
D
L
N
R
T
R
E
L
A
P
K
L
G
---
H
N
---
V
T
V
I
S
E
S
G
I
-
N
T
Y
A
Q
V
R
E
L
S
-
H
F
A
N
G
F
L
I
G
S
A
L
M
A
H
D
D
L
H
A
A
V
R
R
V
-------
44
HHSearch
63.74
34%
12
- C1 -
3QJA
1
TRPC_MYCTU
A:
[6-260]
---
V
L
D
S
I
L
E
G
V
R
A
D
V
A
A
R
E
A
S
V
--
S
L
S
E
I
K
A
A
A
A
A
APP
P
-----
L
D
V
M
A
A
L
R
----
E
P
G
I
G
V
I
A
E
V
K
-------------
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
S
I
P
V
L
R
K
D
F
-
V
V
Q
P
Y
Q
I
H
E
A
-
R
A
H
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
D
R
T
E
S
L
-
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
-
A
G
A
K
V
I
G
V
N
A
R
D
L
M
T
L
D
V
D
R
D
C
F
A
R
I
A
P
G
L
P
---
S
S
---
V
I
R
I
A
E
S
G
V
-
R
G
T
A
D
L
L
A
Y
A
G
A
G
A
D
A
V
L
V
G
E
G
L
V
T
S
G
D
P
R
A
A
V
A
D
L
V
T
-----
9
PsiBlast_PDB
63.68
36%
-52
- C1 -
1JCM
5
TRPC_ECOLI
P:
[33-249]
----------------------------
Q
P
-
S
-------
T
-----
R
H
F
Y
D
A
L
Q
G
A
--
R
--
T
A
F
I
L
E
C
K
K
A
S
P
S
K
G
V
I
R
D
D
F
D
P
A
R
I
A
A
I
Y
K
H
-
Y
A
S
A
I
S
V
L
T
D
E
K
Y
F
Q
G
S
F
N
F
L
P
I
V
S
Q
I
A
P
Q
P
I
L
C
K
D
F
I
I
-
D
P
Y
Q
I
Y
L
A
-
R
Y
Y
Q
A
D
A
C
L
L
M
L
S
V
L
D
D
D
Q
Y
R
Q
L
A
A
V
A
H
S
L
-
E
M
G
V
L
T
E
V
S
-
N
E
E
E
Q
E
R
A
I
-
A
L
G
A
K
V
V
G
I
N
N
R
D
L
C
D
L
S
I
D
L
N
R
T
R
E
L
A
P
K
L
G
---
H
N
---
V
T
V
I
S
E
S
G
I
-
N
T
Y
A
Q
V
R
E
L
S
-
H
F
A
N
G
F
L
I
G
S
A
L
M
A
H
D
D
L
H
A
A
V
----------
3
PsiBlast_PDB
63.60
38%
-48
- C1 -
1J5T
-
TRPC_THEMA
A:
[22-232]
-----------------------------------------------
F
L
E
V
L
S
G
K
--
E
R
-
V
K
I
I
A
E
F
K
K
A
S
P
S
A
G
D
I
N
A
D
A
S
L
E
D
F
I
R
M
Y
D
E
L
-
A
D
A
I
S
I
L
T
E
K
H
Y
F
K
G
D
P
A
F
V
R
A
A
R
N
L
T
C
R
P
I
L
A
K
D
F
Y
I
-
D
T
V
Q
V
K
L
A
-
S
S
V
G
A
D
A
I
L
I
I
A
R
I
L
T
A
E
Q
I
K
E
I
Y
E
A
A
E
E
L
-
G
M
D
S
L
V
E
V
H
-
S
R
E
D
L
E
K
V
F
S
V
I
R
P
K
I
I
G
I
N
T
R
D
L
D
T
F
E
I
K
K
N
V
L
W
E
L
L
P
L
V
P
---
D
D
---
T
V
V
V
A
E
S
G
I
-
K
D
P
R
E
L
K
D
L
R
-
G
K
V
N
A
V
L
V
G
T
S
I
M
K
A
E
N
P
R
R
------------
5
PsiBlast_PDB
63.48
37%
-44
- C1 -
3T44
2
TRPC_MYCTU
A:
[52-259]
------------------------------------------------------------
I
G
V
I
A
E
V
K
R
A
S
P
S
A
G
A
L
A
T
I
A
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
S
I
P
V
L
R
K
D
F
V
V
-
Q
P
Y
Q
I
H
E
A
-
R
A
H
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
D
R
T
E
S
L
-
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
A
G
A
-
K
V
I
G
V
N
A
R
D
L
M
T
L
D
V
D
R
D
C
F
A
R
I
A
P
G
L
P
---
S
S
---
V
I
R
I
A
E
S
G
V
-
R
G
T
A
D
L
L
A
Y
A
G
A
G
A
D
A
V
L
V
G
E
G
L
V
T
S
G
D
P
R
A
A
V
A
D
L
V
------
41
HHSearch
61.90
35%
38
- C1 -
1I4N
1
TRPC_THEMA
A:
[2-248]
---
R
L
W
E
I
V
E
A
K
K
K
D
I
L
E
I
D
G-
E
--
N
L
I
V
Q
R
R
-------
N
-----
H
R
F
L
E
V
L
S
G
---
K
E
R
V
K
I
I
A
E
F
K
K
A
S
P
S
A
G
D
I
N
A
D
A
S
L
E
D
F
I
R
M
Y
D
E
-
L
A
D
A
I
S
I
L
T
E
K
H
Y
F
K
G
D
P
A
F
V
R
A
A
R
N
L
T
C
R
P
I
L
A
K
D
F
-
Y
I
D
T
V
Q
V
K
L
A
-
S
S
V
G
A
D
A
I
L
I
I
A
R
I
L
T
A
E
Q
I
K
E
I
Y
E
A
A
E
E
L
-
G
M
D
S
L
V
E
V
H
-
S
R
E
D
L
E
K
V
F
S
V
I
R
P
K
I
I
G
I
N
T
R
D
L
D
T
F
E
I
K
K
N
V
L
W
E
L
L
P
L
V
P
---
D
D
---
T
V
V
V
A
E
S
G
I
-
K
D
P
R
E
L
K
D
L
R
-
G
K
V
N
A
V
L
V
G
T
S
I
M
K
A
E
N
P
R
R
F
L
E
E
M
R
A
-----
8
PsiBlast_PDB
60.74
36%
-50
- C1 -
1PII
1
TRPC_ECOLI
A:
[33-249]
----------------------------
Q
P
-
S
-------
T
-----
R
H
F
Y
D
A
L
Q
G
A
--
R
--
T
A
F
I
L
E
C
K
K
A
S
P
S
K
G
V
I
R
D
D
F
D
P
A
R
I
A
A
I
Y
K
H
-
Y
A
S
A
I
S
V
L
T
D
E
K
Y
F
Q
G
S
F
N
F
L
P
I
V
S
Q
I
A
P
Q
P
I
L
C
K
D
F
I
I
-
D
P
Y
Q
I
Y
L
A
-
R
Y
Y
Q
A
D
A
C
L
L
M
L
S
V
L
D
D
D
Q
Y
R
Q
L
A
A
V
A
H
S
L
-
E
M
G
V
L
T
E
V
S
-
N
E
E
E
Q
E
R
A
I
-
A
L
G
A
K
V
V
G
I
N
N
R
D
L
R
D
L
S
I
D
L
N
R
T
R
E
L
A
P
K
L
G
---
H
N
---
V
T
V
I
S
E
S
G
I
-
N
T
Y
A
Q
V
R
E
L
S
-
H
F
A
N
G
F
L
I
G
S
A
L
M
A
H
D
D
L
H
A
A
V
----------
10
PsiBlast_PDB
60.55
37%
-40
- C1 -
4FB7
1
TRPC_MYCTU
A:
[55-262]
------------------------------------------------------------
I
G
V
I
A
E
V
K
R
A
S
P
S
A
G
A
L
A
T
I
A
D
P
A
K
L
A
Q
A
Y
Q
D
G
G
A
R
I
V
S
V
V
T
E
Q
R
R
F
Q
G
S
L
D
D
L
D
A
V
R
A
S
V
S
I
P
V
L
R
K
D
F
V
V
-
Q
P
Y
Q
I
H
E
A
-
R
A
H
G
A
D
M
L
L
L
I
V
A
A
L
E
Q
S
V
L
V
S
M
L
D
R
T
E
S
L
-
G
M
T
A
L
V
E
V
H
-
T
E
Q
E
A
D
R
A
L
K
A
G
A
-
K
V
I
G
V
N
A
R
D
L
M
T
L
D
V
D
R
D
C
F
A
R
I
A
P
G
L
P
---
S
S
---
V
I
R
I
A
E
S
G
V
R
G
T
A
D
L
L
A
Y
A
G
A
-
G
A
D
A
V
L
V
G
E
G
L
V
T
S
G
D
P
R
A
A
V
A
D
L
V
------
15
PsiBlast_PDB
58.45
34%
-24
- C1 -
1LBL
1
TRPC_SULSO
A:
[46-238]
-------------------------------------------------------------
A
I
I
A
E
Y
K
R
K
S
P
S
G
L
D
V
E
R
D
--
P
I
E
Y
S
K
F
M
E
R
Y
-
A
V
G
L
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
S
I
P
I
L
M
K
D
F
-
I
V
K
E
S
Q
I
D
D
A
-
Y
N
L
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
E
Y
A
R
S
Y
-
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
I
-
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
E
I
N
K
E
N
Q
R
K
L
I
S
M
I
P
---
S
N
---
V
V
K
V
A
E
S
G
I
-
S
E
R
N
E
I
E
E
L
R
K
L
G
V
N
A
F
L
I
G
S
S
L
M
R
N
-----------------
16
PsiBlast_PDB
58.34
34%
-22
- C1 -
1A53
1
TRPC_SULSO
A:
[46-238]
-------------------------------------------------------------
A
I
I
A
E
Y
K
R
K
S
P
S
G
L
D
V
E
R
D
--
P
I
E
Y
S
K
F
M
E
R
Y
-
A
V
G
L
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
S
I
P
I
L
M
K
D
F
-
I
V
K
E
S
Q
I
D
D
A
-
Y
N
L
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
E
Y
A
R
S
Y
-
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
I
-
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
E
I
N
K
E
N
Q
R
K
L
I
S
M
I
P
---
S
N
---
V
V
K
V
A
E
S
G
I
-
S
E
R
N
E
I
E
E
L
R
K
L
G
V
N
A
F
L
I
G
S
S
L
M
R
N
-----------------
14
PsiBlast_PDB
58.33
34%
-22
- C1 -
1LBF
1
TRPC_SULSO
A:
[46-238]
-------------------------------------------------------------
A
I
I
A
E
Y
K
R
K
S
P
S
G
L
D
V
E
R
D
--
P
I
E
Y
S
K
F
M
E
R
Y
-
A
V
G
L
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
S
I
P
I
L
M
K
D
F
-
I
V
K
E
S
Q
I
D
D
A
-
Y
N
L
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
E
Y
A
R
S
Y
-
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
I
-
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
E
I
N
K
E
N
Q
R
K
L
I
S
M
I
P
---
S
N
---
V
V
K
V
A
E
S
G
I
-
S
E
R
N
E
I
E
E
L
R
K
L
G
V
N
A
F
L
I
G
S
S
L
M
R
N
-----------------
13
PsiBlast_PDB
58.18
34%
-25
- C1 -
1JUL
1
TRPC_SULSO
A:
[47-239]
-------------------------------------------------------------
A
I
I
A
E
Y
K
R
K
S
P
S
G
L
D
V
E
R
D
--
P
I
E
Y
S
K
F
M
E
R
Y
-
A
V
G
L
S
I
L
T
E
E
K
Y
F
N
G
S
Y
E
T
L
R
K
I
A
S
S
V
S
I
P
I
L
M
K
D
F
-
I
V
K
E
S
Q
I
D
D
A
-
Y
N
L
G
A
D
T
V
L
L
I
V
K
I
L
T
E
R
E
L
E
S
L
L
E
Y
A
R
S
Y
-
G
M
E
P
L
I
E
I
N
-
D
E
N
D
L
D
I
A
L
R
I
-
G
A
R
F
I
G
I
N
S
R
D
L
E
T
L
E
I
N
K
E
N
Q
R
K
L
I
S
M
I
P
---
S
N
---
V
V
K
V
A
E
S
G
I
-
S
E
R
N
E
I
E
E
L
R
K
L
G
V
N
A
F
L
I
G
S
S
L
M
R
N
-----------------