@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA0112: (2015-12-22 )
MSGATRKPGFTVAVLATLLAAVVVLLGAYTRLTHAGLGCPDWPGCYGFVHVPLSEAQLAHAELHFPDAPVEAQKGWNEMIHRYFAGALGLLILGLALHALVRRGRDGQPLKLPLLLLAVVIAQAAFGMWTVTLKLWPQVVTAHLLGGFTTLALLFLLALRLSGRFAARRYPAATRGLAGLALLLVIGQIALGGWVSSNYAAVACIDLPTCHGEWWPRMDFANGFHLTQHIGPNYLGGQLDSDARTAIHMTHRIGALCVTLVLLLLAWRLQRSGLVWPTALMLLGLSLQIGLGISNVLLHLPLPVAVAHNGGGALLLLSLVLVNYRLRAPASVRAPAPSPQRVRRTLPPAQGSRLKAA
Atome Classification :
(16 SA)
--------------.........10--.....---....20........30........-40.........50.---------.....---..60........70....------....80....--...-.90---...--------.....100.......110.......120----...---.....130....----------..--.140....---..----.150..-------.....------160..--------------..---...170.---......180.....------------------------..190----.........200--........210.--.....---.220..---.....230--....--....240--...----.....-.250-----......--.260.......270...---....280.......290.......300........310.......320----------------.......-.330.......340.......350......---------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------MSGATRKPG
F
---
T
V
A
V
L
---
A
T
L
L
A
A
V
V
V
L
L
G
A
Y
T
R
L
THAGLGC-P-DWPG
C
Y
G
F
V
HVP---------LSEAQ---LA
H
A
E
LHFPDAP
V
E
A
Q
K
G
------
W
N
E
M
I
H
R
Y
F
A
--
G
A
L
-
G
L
L
---
I
L
G
--------
L
A
L
H
A
L
V
RRGRDGQP
L
K
L
P
L
L
L
L
A
V
V
I
-----
A
Q
A
---AF
G
M
W
T
V
T
L
K
L
W
----------
P
Q
--
V
V
T
A
H
L
L
G
---
G
F
----
T
T
L
A
L
L
-------
F
L
L
A
L
------
R
LSGR--------------FA---ARRYPAA---TR
G
L
A
G
L
A
L
L
L
V
I
G
------------------------
Q
I
A------LG
G
W
VSS
N
Y
A
A
---
V
A
C
I
DLPTCHGE--WWPRM---DFANG
F
---
H
L
T
Q
HIG---PNYL--GGQLD----SD
A
----
R
T
A
I
H
-
M
T
H
R
-----
I
G
A
L
C
V
--
T
L
V
L
L
L
L
A
W
R
L
QRSGL
V
---
W
P
T
A
L
M
L
L
GL
S
L
Q
IGLG
I
S
N
V
L
L
HLP-L
P
V
A
V
AHNG
G
G
A
L
L
L
L
S
L
V
L
-----------------
V
N
YRLRA-PASVRAPAP
S
P
Q
R
V
R
R
TLPPAQG-SRLKAA---------------------------------------------
17
Fugue
83.36
22%
-103
- C7 -
4QPP
3
ANM6_HUMAN
A:
[48-376]
YYEC
Y
S
D
V
S
V
H
E
E
M
I
A
D
R
V
R
T
D
A
Y
---
R
L
G
I
L
R
N
W
A
A
L
R
G
K
T
V
L
D
V
G
A
G
T
G
I
L
S
I
F
C
A
Q
-
A
-
G
A
R
R
V
Y
A
V
E
A
S
A
---------
I
W
Q
Q
A
---
R
E
V
V
R
F
N
G
L
E
D
R
V
H
V
L
P
G
P
VETVE
L
P
E
Q
V
D
A
I
V
S
EW
M
G
Y
-
G
L
L
HES
M
L
S
--------
S
V
L
H
A
R
T
K
W
L
K
E
G
G
L
L
L
P
A
S
A
E
L
F
I
V
P
I
SD
Q
M
L
E
W
---
R
L
G
F
W
S
Q
V
K
Q
H
Y
----------
G
----
V
D
M
S
C
L
E
---
G
F
----
A
T
R
C
L
M
GHS----
E
I
V
V
Q
------
G
L
S
G
E
--------------
D
V
LAR
P
Q
R
F
A
Q
L
---
E
L
S
R
A
G
L
E
Q
E
L
E
A
G
------------------------
V
---------
G
G
R
F
R
C
S
--------
C
Y
G
S
A
P
M
H
G
------------
F
A
I
W
F
---
Q
V
T
F
P
G
G
---
E
S
E
K
--
P
L
V
L
S
----
T
S
P
----
F
H
P
---
A
T
H
----------------------------------
W
K
Q
A
L
L
Y
L
N
E
P
V
Q
V
E
Q
D
-
T
D
V
S
---------------
G
E
I
T
L
L
P
S
R
D
-----------------
N
P
R
R
L
R
V
-
L
L
R
Y
K
V
G
D
Q
E
E
K
T
K
D
F
A
M
E
D
-------------------------------------------------------
11
Fugue
75.49
16%
-153
* C12 *
2VDU
-
TRM82_YEAST
B:
[2-436]
-------SVIHPLQ
N
L
L
T
S
R
D
G
S
L
---
V
F
A
I
I
---
K
N
--
C
I
L
S
F
K
Y
Q
S
P
N
H
W
E
F
A
G
K
W
S
-
D
-
D
F
P
I
Y
S
Y
I
R
N
L
R
---------
L
T
S
D
E
S
R
L
I
A
C
A
-----------------------------
D
--
S
D
K
-
S
L
L
---
V
F
D
V
D
KTSKNV
L
K
L
R
K
R
F
C
F
S
K
R
P
N
A
I
S
I
A
E
D
D
T
T
V
I
I
-----
A
D
K
---
F
G
D
V
Y
S
I
D
I
N
S
I
----------
P
E
E
K
F
T
Q
E
P
I
L
G
HVS
M
L
----
T
D
V
H
L
I
K
D
SDG
H
Q
F
I
I
T
S
------
D
R
D
E
H
--------------
I
K
---
I
S
H
Y
P
Q
C
FIV
D
K
W
L
F
G
H
K
H
F
--
V
S
------------------------
S
I
C
------
C
G
----
K
D
Y
L
L
---
L
S
A
G
G
D
D
K
I
F
A
W
--
D
W
K
T
G
---
K
N
L
S
T
F
---
D
Y
N
S
L
I
K
---
P
-
Y
L
--
N
D
Q
H
L
----
A
I
I
----
E
F
A
V
S
-
K
I
I
K
S
K
N
LP
F
V
A
F
F
V
E
A
T
K
C
I
I
I
L
E
M
S
E
K
Q
K
G
D
L
---
A
L
K
Q
I
I
T
F
P
Y
N
V
-
I
S
L
S
A
H
N
D
E
F
Q
V
T
-
L
D
N
K
E
S
S
G
V
Q
K
N
F
----
A
K
F
-----------------
I
E
Y
N
L
N
E
-
N
S
F
V
V
N
N
E
K
S
N
E
F
D
S
A
I
I
Q
S
V
Q
G
D
S
N
L
V
T
K
KEEIYPLYNVSSL--------------------------------
18
Fugue
73.57
17%
-124
- C6 -
4GA6
3
AMPPA_THEKO
A:
[1-493]
--------------
M
K
A
K
I
R
I
L
D
M
FSG
R
Y
T
V
L
---
I
N
E
E
D
A
K
E
A
K
L
H
P
D
D
L
V
K
I
E
-----
A
-
G
K
K
A
V
Y
G
S
V
A
L
S
NLVGKG
E
V
G
I
S
R
D
V
---
L
D
L
H
N
F
S
-
E
G
E
T
V
S
V
I
P
A
------
G
T
P
E
S
V
R
Y
I
K
--
K
K
M
H
G
E
K
---
L
R
K
--------
V
E
I
E
A
I
V
R
D
I
V
D
R
K
L
R
D
I
E
I
S
S
F
V
T
A
L
-----
E
I
N
GLD
M
D
E
I
A
A
L
T
I
A
M
A
E
T
G
D
M
L
D
I
DR
K
P
--
I
M
D
V
H
S
I
G
---
G
V
PGNK
T
N
I
L
V
V
-------
P
I
V
A
A
A
GLTIP
K
T
S
S
R
A
ITSAAG
T
A
D
V
V
E
V
F
A
DV-
S
F
S
L
D
E
I
---
K
R
I
V
E
K
V
G
A
C
L
V
W
G
GALNLA
P
A
D
D
I
T
I
K
A
E
R
A
L
SIDP
T
G
L
M
------
L
A
S
I
M
S
K
K
Y
A
M
GSQ
Y
V
L
I
D
I
P
T
G
K
G
V
--
K
V
E
T
V
---
E
E
A
R
S
L
---
A
R
D
F
I
E
L
---
G
K
R
L
--
G
Q
Y
V
E
----
V
A
I
----
T
Y
G
G
Q
P
I
G
H
T
-----
V
G
P
A
L
E
--
A
R
E
A
L
S
A
L
M
T
G
K
G
P
G
S
L
---
I
E
K
A
T
G
L
A
G
I
L
L
E
M
G
-
G
V
A
P
A
G
T
G
K
K
-
M
A
K
E
I
L
E
S
G
K
A
W
E
K
M
K
E
I
I
E
A
Q
GGDPNIKPEEIPIGD
K
T
Y
T
F
T
A
-
A
T
S
G
Y
V
T
A
I
D
N
R
A
I
T
A
I
A
R
A
A
G
A
-
P
E
D
K
G
A
G
I
E
L
YVKVG
E
K
V
K
EGDPL
F
T
I
H
A
EH
E
A
R
L
D
Q
A
I
V
L
A
R
R
T
EPIRIE
16
Fugue
63.00
22%
-75
- C8 -
2XQH
4
?
A:
[23-280]
---------------
S
D
A
K
A
S
G
E
F
---
S
V
A
V
G
---
N
----------
G
A
R
A
T
-
E
K
A
S
T
A
V
-
G
-
S
W
A
A
A
D
G
K
Q
S
T
A
---------
L
G
V
G
T
---
Y
A
Y
A
N
A
---------------------------
S
--
T
A
L
-
G
S
V
-------------------------------------
A
F
V
D
-----
N
T
A
---
T
Y
G
-------------------------
T
A
A
G
N
R
---------------------------------------------------------
A
K
V
D
K
D
A
---
T
E
G
T
A
L
G
A
K
A
T
V
---------------------------------------
T
N
K
N
S
V
A
---
L
G
A
N
S
V
T
T
R
D
N
E
--
V
Y
I
-----
G
Y
K
T
G
T
---
E
S
D
K
T
Y
G
---
T
R
V
L
--
G
G
L
S
D
GTRN
S
D
A
----
A
T
V
G
Q
-
L
N
R
K
-----
V
G
G
V
Y
D
--
D
V
K
A
R
I
T
V
E
S
E
K
Q
K
K
Y
T
D
Q
K
T
S
E
V
N
E
K
V
E
A
R
T
T
V
G
V
D
S
D
G
K
L
T
R
A
E
G
A
T
K
T
I
A
V
N
D
G
L
V
A
L
S
G
R
T
D
R
-----------------
I
D
Y
A
V
G
A
I
D
G
R
V
T
R
N
T
Q
S
I
E
K
N
S
K
A
I
A
A
N
T
R
-
T
--------------------------------------------------
14
Fugue
43.21
17%
-59
- C9 -
4WLP
-
NFRKB_HUMAN
B:
[1-114]
-------------------------------------------
E
D
L
L
E
D
P
E
I
F
F
D
V
V
S
L
-
S
-
T
W
Q
E
-------
V
---------
L
S
D
S
Q
---
R
E
H
L
Q
Q
F
L
P
Q
F
P
E
D
S
A
E
Q
------
Q
N
E
L
I
L
A
L
F
S
--
G
E
N
---
F
---
R
F
G
--------
N
P
L
H
I
A
Q
K
L
F
R
D
G
H
F
N
P
E
V
V
K
Y
R
Q
L
C
F
-----
K
S
Q
---
Y
K
R
Y
L
N
S
Q
Q
Q
Y
F
----------
H
R
--
L
L
K
Q
I
L
A
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
40.31
18%
-91
- C10 -
2E6Q
-
A:
[1-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
S
G
S
S
G
---
T
A
R
L
V
A
G
L
E
D
V
Q
--
V
Y
D
G
E
---
D
A
V
F
S
L
---
D
L
S
T
I
I
Q
---
G
T
W
F
L
N
G
E
E
L
K
----
S
N
E
P
E
G
Q
V
E
P
G
A
-
L
R
Y
R
-----
I
E
Q
K
G
L
--
Q
H
R
L
I
L
H
A
V
K
H
Q
D
S
G
----------------
A
L
V
G
F
S
C
P
G
V
Q
D
S
A
A
-
L
T
I
Q
E
S
S
G
P
S
S
G
------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
34.24
33%
-47
* C13 *
3WEC
2
?
A:
[22-98]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
K
---
A
D
P
Y
P
V
Y
---
A
R
----
L
R
T
E
L
P
I
H
------------------------
R
S
A
------
L
G
A
W
I
V
A
D
Y
T
-----------
S
C
D
K
V
--
L
R
S
R
L
FGK
D
F
A
N
S
T
F
F
D
H
L
T
S
M
M
G
EDM
P
P
F
L
--
G
L
G
I
D
----
G
D
A
----
R
P
F
M
L
-
T
D
P
P
-----
E
H
T
R
L
R
--
G
L
V
S
D
A
F
T
R
S
T
T
T
S
M
D
D
---
I
V
L
S
A
A
S
S
A
V
R
H
L
E
H
C
T
D
A
V
S
E
V
A
E
P
-
F
P
V
E
V
L
S
S
I
L
G
I
P
D
K
D
R
G
R
F
-----------------
S
E
W
S
N
L
V
-
A
G
V
L
D
I
N
F
A
I
P
K
E
V
A
D
R
R
S
A
A
I
E
-
E
S
I
D
Y
F
---------------------------------------------
2
HHSearch
32.93
50%
650
- C4 -
1WQB
-
TXP7_APOSC
A:
[9-22]
--------------------------------------------------------
E
A
C
G
P
W
E
W
P
C
C
S
G
L
K
C
D
G
---------
S
E
C
H
P
---
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
25.90
33%
544
- C5 -
2NX6
-
?
A:
[3-14]
--------------------------------------------------------
S
S
C
-
P
-
Q
F
P
S
C
S
P
S
C
A
P
Q
---------
C
S
Q
Q
C
---
C
Q
Q
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
Fugue
25.56
29%
84
- C11 -
4OZK
-
?
A:
[1-49]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
CQCPDA
I
S
G
W
T
H
T
D
Y
------------
Q
C
H
G
L
EN
K
M
Y
R
H
---
V
Y
A
I
C
M
---
N
G
T
Q
V
Y
C
---
R
T
E
W
--
G
S
S
C
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
22.04
23%
165
- C12 -
1QLO
-
ICP47_HHV11
A:
[1-34]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
W
A
L
---
E
M
A
D
T
F
---
L
D
N
M
R
V
G
---
P
R
T
-------
Y
----
A
D
V
----
R
D
E
I
N
-
K
R
G
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
20.58
13%
17
- C13 -
2QJY
-
CYB_RHOSH
A:
[44-66]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
W
I
W
G
V
V
L
A
F
C
L
V
L
------------------------
Q
I
V
------
T
G
I
V
L
A
M
H
Y
T
P
---
H
V
D
L
A
F
A
S
V
E
H
I
--
M
R
N
V
N
---
G
G
F
M
L
R
---
Y
L
H
A
N
G
A
---
S
L
F
F
--
I
A
V
Y
L
----
H
I
F
----
R
G
L
Y
Y
-
G
S
Y
K
-----
A
P
R
E
V
T
--
W
I
V
G
M
L
I
Y
L
A
M
M
A
T
A
F
M
---
G
Y
V
L
P
W
G
Q
M
S
F
W
G
A
T
V
I
T
G
L
F
G
A
I
P
G
-
I
G
H
S
I
Q
T
W
L
L
G
G
P
A
V
D
N
A
T
L
-----------------
N
R
F
F
S
L
H
-
Y
L
L
P
F
V
I
A
A
L
V
A
I
H
I
W
A
F
H
S
T
G
N
-
N
N
P
T
G
V
---------------------------------------------
4
HHSearch
19.15
17%
175
- C13 -
1KQF
1
FDNI_ECOLI
C:
[53-70]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
I
L
H
P
F
F
---
G
I
----
A
I
F
V
A
L
-------
M
F
M
F
V
------
R
F
V
H
H
--------------
N
I
---
P
D
K
K
D
I
P
---
W
L
L
N
I
V
E
V
L
K
G
N
E
H
------------------------
K
V
A
------
D
V
G
K
Y
N
A
G
Q
K
M
---
M
F
W
S
I
M
S
M
I
F
V
L
--
L
V
T
G
V
---
I
I
W
R
P
Y
---
F
A
Q
Y
F
P
M
---
Q
V
V
R
--
Y
S
L
L
I
----
H
A
A
----
A
G
I
I
L
-
I
H
A
I
-----
L
I
H
M
Y
M
--
A
F
W
V
K
G
S
I
K
G
M
I
E
G
K
V
S
---
R
R
W
A
K
K
H
H
P
R
W
Y
R
E
I
E
K
A
E
A
K
K
E
S
E
E
-
G
I
----------------------------------------------------------------------------------------------------------------------
7
HHSearch
15.20
50%
1372
- C1 -
1JLP
-
CM3F_CONPU
A:
[9-18]
---------------------------------------------------------
S
C
-
R
--
F
-
G
C
Y
N
A
L
C
C
R
---------
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
7.44
44%
1442
- C3 -
1YK1
-
E:
[11-19]
---------------------------------------------------
S
S
S
S
G
L
G
C
-
K
-
V
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
7.24
44%
1442
- C2 -
1YK0
-
E:
[11-19]
---------------------------------------------------
G
A
Q
S
G
L
G
C
-
N
-
S
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------