@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA4879: (2016-03-02 )
MTRGRKILTWSLASLVLLLAALVVFIATFDWNLIKPTLNEKVSAALNRPFAINGNLAVAWRREEGEEGWRAWIPWPRFSAEDITLGNPEWTAGKTKASEFASLERIEFRLAPLPLLWQTIRIPQIKLTQPRAELLRLADGRANWDFDLPASDSDEPSAWQLDIREIGFDKGSVSLDDQRLKTRLEVLVDPLGKPVPFGQLAGKALATGDAANAQDYVFGWKVKGTYKGQALAGSGKVGGMLALQDASKPFPLQAEVSAGSTRAAVVGTLTDPLNLGALDLRLKLSGTSMANLYPLTGITLPDTPAYSTDGHLLARLKEEGGALFRYENFNGKVGASDLHGSLTFVARQPRPKLSGKLTSEQLRFADLGPLIGADSNAEKQKRGQTSRQPGDKVLPVEEFRTERWRDMDADVEFTGKRIVHSDQLPISDLYTHLVLNDGLLRLEPLRFGVAGGKLESDIRLDGGKQPMQSRVKMSARGFKLKQLFPGFAPMQTSFGELNGDASLSGSGNSVAKILGGADGELKMLINDGAISKGLTEIAGLNVGNYLVTKLFGDDEVKINCAAADFGLQKGLMTSRLFVFDTENALVNVDGTVNFANEKLDLDVTPHSKGLRIFSLRSPLYVRGTFAKPDAGVHAGPLVARGAGMIALGVTVGPAASLLALVAPSKSDDNQCTALLQRMRLPAKVPAGKR
Atome Classification :
(12 SA)
---------------.........10........20.....-...30.---------......--.40--.......-..50........60-----....--....70........80........90...--.....100.......110....---...120....------.....130---........140.......150.-......160.......170--....----...180.......190.......200--.....-----..210.....-..220.......230..-.....240.......-------------250.....-------..260....-...----270----.......280--------.......290.....-..300.......310...--....320.......330-----------..---......340.......350.......360...---------....370---.........380.......390.......400-........410--------.........420--...-----......430.......--440..-.----....450......--------------------..460.......470...--.....480.......490.......500......-.510-.........520.......530.......540....----..-.550-------------.......560.......570.......580.....------------..590......--.600.......610-.........620---........--------------630...-----....640.......650.......660.......670.......-680.......---------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------MTRG
R
K
I
L
T
W
S
L
A
S
L
V
L
L
L
A
A
L
V
V
F
I
-
A
TFDWN---------LIK
P
T
L
--
N
E
---
K
V
S
A
A
LN-R
P
F
A
ING
N
L
A
V
A
W
R-----REEG--EE
G
W
R
AWIPWPRFSAEDITLGNPEWTAGK--
T
K
A
S
E
F
A
S
L
E
R
I
E
F
RLA
P
L
P
L
L
---
W
Q
TI--RIP
Q
------
I
K
LTQ
P
R
----
A
E
L
L
R
LADGRANWDFDLPASDS-DEPS
A
W
Q
L
D
I
R
EIGFDKGS--VS
L
D
----
D
Q
R
L
K
T
R
L
E
V
L
V
DPLGKPV
P
F
G
Q
LAG--KALAT-----GDAANAQ
D
Y
V
-
F
G
W
K
V
K
G
T
YKG
Q
A
LAGS-GKV
G
G
M
L
A
LQDASKP-------------FP
L
Q
A
E
VS-------AGS
T
R
A
A
V
V
-
G
TL----TDP----LNL
G
A
L
D
L
R
L
--------
K
LSGTS
M
A
N
L
Y
PLTG-ITLPDTPAYSTD
G
H
L
L
A
R
--
L
K
EEG
G
A
L
F
R
YENFNG------------KV---GASDLHG
S
L
T
F
V
ARQPRPKLSGKL
T
S
E
QLRFA---------DLGPL-----IGADS
N
A
E
K
Q
KRGQTSRQPGDKVL
P
V
E
E
F
R
T
--
E
R
WRDMDAD----------
V
E
FTG
K
R
I
VH----SDQ-----L
P
I
S
D
L
Y
T
H
L
VLNDG
L
--
L
R
L
E
P
-
L
----
R
FGVAG-GKL
E
S
D
--------------------
I
RLDGGKQ
P
M
Q
S
R
-
V
K
MS--ARGF
K
L
K
Q
LFPGFAPMQTSFGELNGDASLSGSG
N
-
S
V
---
A
K
I
L
GGADG
E
L
K
M
L
INDGAIS
K
G
L
T
E
I
AGLN
V
G
N
Y
L
----
V
T
-
K
LFG-------------DD
E
V
K
I
N
C
A
AA
D
F
G
L
QKGLMT
S
R
L
F
V
F
DTEN
A
L
V
N------------VDG
T
V
N
FAN
E
K
--
L
D
L
D
VTPHSKG
L
---
R
I
F
SLRS
P
L
Y
V
----RGTFAKPD--------------AGVHAG-----
P
L
VARGA
G
M
I
A
L
G
V
TVG
P
A
A
S
L
L
A
LVAPSKSD
D
N
Q
C
T
A
L
L
Q
R
MR-LPAKVPAGKR---------------------------
13
Fugue
86.93
16%
-17
- C7 -
4M1K
2
?
A:
[6-688]
EYDLKR
L
R
N
I
G
I
A
A
H
I
D
A
G
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
A
A
V
T
T
C
F
W
K
D
H
R
I
N
---------
I
I
D
T
P
G
--
H
V
---
D
F
T
I
E
V
E
-
R
S
M
R
V
L
D
G
A
I
V
V
F
D
-----
S
S
Q
G
VE
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
---
M
D
K
--
T
G
A
D
L
W
L
V
I
R
T
M
Q
E
R
L
G
A
R
P
V
V
---
M
Q
L
P
--
I
G
R
E
DTFS
G
I
I
D
V
L
R
M
K
----
A
Y
T
Y
G
N
D
L
G
T
D
I
R
E
I
P
I
P
E
E
Y
L
-
D
Q
A
R
E
Y
H
E
K
L
V
E
V
A
A
D
F
D
------------------
E
N
I
M
L
K
Y
L
E
G
E
E
P
T
E
E
E
L
V
--
A
A
I
R
K
-----
G
T
I
D
L
---------
K
I
T
P
V
F
L
G
S
A
L
K
N
K
-
G
-
V
Q
L
L
L
D
A
V
V
D
Y
L
P
-------------
S
P
L
D
I
P
P
I
-------
K
G
T
T
P
E
G
E
V
-
V
E
I
H
PDP
N
G
P
----
L
A
A
L
A
F
K
I
M
A
--------
D
P
Y
V
G
R
L
T
F
I
R
V
Y
S
G
-
T
L
T
S
G
S
Y
V
Y
N
T
T
----------------------------------------------
K
G
R
K
E
R
V
A
R
L
L
R
M
H
A
N
H
R
E
E
V
E
E
L
K
A
G
---------
D
L
G
A
V
-----
V
G
L
K
E
T
-----------
I
T
G
D
T
L
V
G
E
D
A
P
R
V
IL
E
S
I
E
V
P
E
P
V
----------
I
D
V
A
I
E
P
K
T
K
----
A
D
Q
-----
E
K
L
S
Q
A
L
A
R
L
A
E
E
D
P
T
--
F
R
V
S
T
-
H
PET
G
Q
T
I
I
S
G
M
G
E
L
H
L
E
--------------------
I
I
V
D
R
L
K
R
E
F
K
V
D
-
A
N
V
G
--
K
P
Q
V
A
Y
R
E
T
I
T
K
P
V
D
V
E
G
K
F
I
R
L
T
G
G
R
G
Q
Y
G
H
V
K
I
K
V
---
E
P
L
P
R
G
S
G
F
E
F
V
N
A
I
V
G
G
V
I
P
K
E
Y
I
P
A
V
Q
K
G
I
E
E
A
M
----
Q
S
G
P
L
I
G
-------------
F
P
V
V
D
I
K
V
T
L
Y
D
G
S
Y
H
E
V
D
S
S
E
M
A
F
K
I
A
G
S
M
A
I
K
E
------------
A
V
Q
K
G
D
P
V
I
L
E
--
P
I
M
R
V
E
V
T
T
P
E
E
---
Y
M
G
D
V
I
G
D
L
N
A
----
R
R
---------------------
G
Q
I
L
G
-----
M
E
P
R
G
N
A
Q
V
I
R
A
F
V
P
L
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
K
Q
V
Q
E
K
L
I
---------------------------
18
Fugue
85.83
17%
-2
- C3 -
3W36
1
?
A:
[58-527]
------------------------------------------------------------------------------
I
E
F
D
L
D
K
D
N
Y
I
K
W
A
-----
Q
P
T
D
--
E
N
A
G
Q
--------
S
P
T
L
A
I
L
G
P
M
D
V
T
V
F
L
W
I
N
R
V
V
W
L
A
A
F
D
A
L
A
P
Y
H
E
T
A
V
G
V
---
Y
S
Q
I
PR
R
P
S
S
------
E
S
A
T
N
R
N
----
L
N
I
A
A
L
H
A
Q
H
G
V
W
K
R
V
L
P
-----
Q
Q
V
D
Q
L
R
E
L
M
T
A
L
G
L
D
P
S
D
--
E
T
E
N
------------------
L
S
S
P
V
G
I
G
N
V
A
A
--
K
N
A
F
N
-----
A
L
K
N
D
G
M
N
F
L
G
Y
E
G
R
K
Y
N
P
R
P
W
A
D
Y
T
G
Y
-
E
P
V
N
T
A
F
K
V
N
N
P
S
R
----------------
W
Q
P
Q
L
Q
-------
A
H
N
A
R
R
A
-------------------------------------------------
G
-
G
G
P
G
D
L
G
I
Y
V
T
Q
H
F
V
T
P
Q
--
T
A
R
T
K
A
H
I
F
R
D
P
S
R
F
-------------------------------
R
I
P
R
P
E
F
S
D
H
T
N
T
R
A
Y
K
-
R
---------
S
V
D
E
I
-----
I
D
A
S
A
N
L
N
-----------
D
E
R
K
A
L
A
E
I
M
E
N
--
K
L
W
-----
G
----------
I
G
H
S
S
I
V
I
A
N
K
Y
D
Q
N
N
E
-----
M
G
V
H
G
-
W
C
H
W
M
L
A
H
V
L
--
A
T
F
E
P
-
L
----
I
A
A
W
H
H
-
K
T
R
F
D
A
--------------------
V
R
---------------------------------
P
V
T
A
I
R
H
V
Y
G
--------
N
-
R
K
---
I
R
A
W
G
G
-------------
V
G
M
G
T
V
D
I
R
A
S
E
W
S
S
Y
L
----
P
V
------------------
G
D
H
P
E
Y
P
S
G
S
T
S
L
C
S
A
T
S
Q
A
A
R
R
Y
F
D
S
D
------
E
------------
L
D
W
T
I
N
Y
P
A
G
S
TV
V
E
P
G
I
T
P
G
K
D
L
S
---
I
H
I
P
T
W
T
D
F
T
R
----
T
C
A
T
S
R
V
W
--------------
G
G
V
H
F
Q
-----
T
T
V
D
R
---
T
I
D
F
G
E
Q
F
G
D
L
A
H
E
F
V
Q
R
H
V
K
G
----------------------------------------------------
12
Fugue
84.53
14%
-32
* C5 *
4AQ1
4
?
A:
[172-892]
-----------------
A
V
P
E
I
V
E
V
T
A
V
N
S
T
T
V
K
V
T
F
N
T
Q
I
-
A
D
V
D
F
T
N
F
A
I
D
NGLT
V
T
K
A
T
L
--
S
R
DKK
S
V
E
V
V
V
N
-
K
P
F
T
R
N
Q
E
Y
T
I
T
A
T
GIKNL
K
G
E
T
--
A
K
E
L
T
G
K
F
V
W
S
V
Q
D
A
V
T
V
A
L
N
N
S
S
L
K
V
G
E
--
E
S
G
L
T
V
K
D
Q
D
G
K
D
V
V
G
A
K
V
E
L
T
S
SN
T
N
I
V
--
V
V
S
S
------
G
E
V
S
V
S
A
----
A
K
V
T
A
V
K
P
G
T
A
D
V
T
A
K
V
T
L
P
D
G
V
V
L
T
N
T
F
K
V
T
V
T
E
V
P
V
Q
V
Q
N
QG
F
T
L
V
----
D
N
L
S
N
A
P
Q
N
T
V
A
F
N
K
A
E
K
V
T
-
S
M
F
A
G
E
T
K
T
V
A
M
Y
D
T
K
N
G
D
P
E
T
K
P
V
D
F
-
K
D
A
T
V
R
S
L
N
P
I
I
A
T
A
A
I
N
G
S
E
L
L
V
T
A
N
A
G
Q
S
G
K
-------------
A
S
F
E
V
T
F
K
-------
D
N
T
K
R
T
F
T
V
-
D
V
K
----
K
E
P
VLQ
D
I
K
V
D
A
T
S
V
K
L
S
DEAVGGG
E
V
E
G
V
N
Q
K
T
I
K
V
S
A
V
-
D
Q
Y
G
K
E
I
K
F
G
T
K
G
K
V
T
V
T
--
T
N
T
E
G
-
L
V
I
K
N
V
N
S
D
N
------------
T
I
DFD
S
G
N
S
A
T
D
Q
F
V
V
V
A
T
K
------
D
K
I
V
N
G
K
V
E
V
K
---------
Y
F
K
N
A
-----
S
D
T
T
P
T
S
T
K
T
I
T
V
N
V
V
N
V
K
A
D
A
T
P
V
G
L
D
I
V
A
--
P
S
E
I
D
V
N
A
P
NTASTADVDF
I
N
F
E
S
V
E
I
Y
T
----
L
D
S
NGNRL
K
K
V
T
P
T
A
T
T
L
V
G
T
N
D
Y
--
V
E
V
N
G
-
N
----
V
L
Q
F
K
G
-
N
---
D
E
--------------------
L
T
L
L
T
S
S
S
T
V
N
V
D
-
V
T
A
D
G
I
T
K
R
I
P
V
K
Y
I
N
S
A
S
V
P
A
S
A
T
V
A
T
S
P
V
T
V
K
L
N
S
S
D
N
-
D
L
T
F
E
E
L
I
F
G
V
I
D
--
P
T
Q
L
V
K
D
E
D
I
N
E
F
I
A
V
S
K
A
A
K
N
D
G
Y
L
YNKP
L
V
-
T
V
K
D
-------------
A
S
G
E
V
I
P
T
G
A
N
V
Y
G
L
N
H
D
----------------
A
------------
T
N
G
N
I
W
F
D
E
E
Q
--
A
G
L
-----
A
K
K
F
---
S
D
V
H
F
D
V
D
F
S
L
----
A
N
V
V
K
T
G
S
--------------
G
T
V
S
S
S
-----
P
S
L
S
D
A
I
Q
L
T
N
S
G
D
A
V
S
F
T
L
V
I
K
S
I
Y
V
K
G
A
D
K
D
D
N
-
N
L
L
A
A
P
V
S
-
V
N
V
T
V
T
K
G
S
----------------------------
17
Fugue
81.16
18%
12
- C4 -
4CCZ
1
METH_HUMAN
A:
[4-638]
-------------------------------------------------------------
T
L
--
R
D
---
E
I
N
A
I
L
Q
K
R
I
M
V
L
D
G
G
M
G
T
M
I
Q
-----
R
E
K
L
--
E
E
H
F
R
G
----
Q
E
F
K
D
H
A
R
P
L
K
G
N
N
D
I
L
S
I
--
T
Q
P
D
V
I
Y
Q
I
H
K
E
Y
L
L
----
A
D
I
---
I
E
T
N
--
T
F
S
S
------
T
S
I
A
Q
A
D
----
Y
G
L
E
H
L
A
Y
-
R
M
N
M
C
S
A
G
V
A
R
K
A
-
A
E
E
V
T
L
Q
T
G
I
K
R
--
F
V
A
G
A
--
L
G
P
T
----
N
K
T
L
S
V
S
P
S
V
-
E
R
P
D
Y
R
N
I
T
F
D
E
L
V
E
A
Y
Q
E
Q
A
K
-----
G
L
L
D
G
G
V
D
I
L
-
L
I
E
T
I
F
D
T
A
N
A
K
A
A
L
F
A
-
L
Q
N
--
L
F
E
E
K
Y
A
P
R
P
-------------
I
F
I
S
G
T
I
V
D
KSGRTL
S
G
Q
T
G
E
G
F
V
-
I
S
V
----
S
H
G
----
E
P
L
-
C
I
G
L
N
C
--------
A
L
G
A
A
E
M
R
P
F
I
E
I
I
G
K
C
T
T
A
Y
V
L
C
Y
P
N
A
G
F
A
M
D
G
--
L
V
N
I
V
G
G
C
C
G
S
T
P
D
H
I
------------
R
E
---
I
A
E
A
V
K
N
C
K
P
R
V
P
--
P
A
T
A
F
E
G
H
M
L
L
S
G
L
E
P
F
---------
R
I
G
P
Y
T
N
F
V
N
I
G
E
R
C
N
V
A
G
S
R
K
F
A
K
L
I
M
A
G
N
--------
Y
E
--
E
A
L
C
V
A
K
V
Q
----------
V
E
M
-
G
A
Q
V
L
D
----
V
N
-----------------
M
D
D
G
M
--
L
D
-
G
P
-
S
----
A
M
T
R
F
C
-
N
L
I
A
S
E
--------------------
P
D
I
A
K
V
P
L
C
I
D
S
S
N
F
A
V
I
--
E
A
G
L
K
C
C
Q
---
G
K
C
-
I
V
N
S
I
S
L
K
E
G
E
D
D
F
L
E
K
A
R
-
K
I
---
K
K
Y
--
G
A
A
M
V
V
M
A
F
D
E
E
G
Q
A
T
E
T
D
T
K
I
R
V
C
T
R
A
Y
H
L
----
L
V
-
K
K
L
G
-------------
F
N
P
N
D
I
I
F
D
P
N
I
L
T
I
G
T
G
M
E
E
H
N
L
Y
A
I
N
F
I
H
A
T
K
V
------------
I
K
E
T
L
P
G
A
--
R
--
I
-------
S
G
G
L
---
S
N
L
S
F
S
F
--------
R
G
M
E
A
I
R
E
--------------
A
M
H
G
V
F
-----
L
Y
H
A
I
K
S
G
M
-
D
M
G
I
V
--
N
A
G
N
L
P
V
Y
D
D
I
H
K
E
L
L
Q
L
C
E
D
L
I
W
N
K
D
-
P
E
A
T
E
K
L
L
R
Y
AQ-------------------------
11
Fugue
72.45
18%
-19
- C7 -
1JJU
3
?
A:
[1-489]
----------------
V
T
G
E
E
V
L
Q
N
A
-------
C
A
A
C
H
V
Q
H
-
E
D
G
R
W
E
---------
R
I
D
A
A
R
K
T
P
E
---
G
W
D
M
T
V
T
-
R
M
M
R
N
H
G
---
V
A
L
E
-----
P
E
E
R
--
A
A
I
V
R
H
L
S
D
T
R
G
L
S
L
A
E
T
----------------------
E
E
R
R
Y
I
L
E
R
E
P
V
A
---
W
D
E
G
--
P
D
T
S
------
M
T
Q
T
C
G
R
CHS
Y
A
R
V
A
L
Q
R
R
T
P
E
D
W
K
H
L
V
N
F
H
L
G
-
Q
F
P
T
L
E
Y
----------
Q
A
--
L
A
R
D
----
R
D
W
W
G
I
A
Q
A
E
I
I
P
F
L
A
R
T
Y
P
L
G
E
-----
A
P
D
A
Y
-----
A
D
D
A
S
G
A
Y
V
L
-
A
G
R
Q
----------
P
G
R
-
G
D
Y
T
G
R
L
V
L
K
K
A
G
E
D
-------------
Y
E
V
T
M
T
L
D
F
A-----
D
G
S
R
S
F
S
G
T
-
G
R
I
----
L
G
A
-------
G
E
W
R
A
T
L
--------
S
D
G
T
V
T
I
R
Q
I
F
A
L
Q
D
-
G
R
F
S
--------
G
R
W
H
D
A
--
D
S
D
V
I
G
---------
G
------------
R
L
---
A
A
V
K
A
D
A
A
P
Q
V
L
A
V
A
P
A
R
L
K
I
G
E
E
T
Q
L
R
V
A
G
T
---------
G
L
G
S
D
-----
L
T
L
P
E
G
V
A
G
--------------------
S
V
--
E
S
A
G
N
G
V
T
V
----------
L
K
L
T
A
T
G
T
P
G
----
P
V
S
-----
L
E
L
G
G
Q
K
V
D
L
V
A
Y
D
R
P
D
R
I
S
I
V
P
D
L
----
T
I
A
R
I
G
-
G
-----------------------------
N
G
G
P
I
P
K
V
P
-
A
Q
F
E
--
A
M
G
W
L
---------------------------------------
N
G
P
D
G
Q
P
G
----------------------------------
T
-------------
G
D
D
I
A
L
G
A
F
P
A
S
W
A
T
D
N
------------
F
D
E
E
A
E
------------
K
M
Q
D
A
K
Y
A
G
--------------------------
S
I
D
D
----
T
G
L
F
T
P
A
E
--------------
A
G
P
N
P
---------
E
R
P
M
Q
--------
T
N
N
A
G
N
L
K
V
I
A
T
V
D
A
E
G
E
P
---
L
S
A
E
A
H
-
L
Y
A
T
V
Q
R
F
V
D
APIR-----------------------
16
Fugue
65.89
10%
0
* C4 *
3UCP
19
?
A:
[45-844]
------------------
G
L
D
I
S
Q
A
T
T
L
K
A
T
L
E
D
V
K
I
D
N
G
T
-
V
S
V
D
I
V
---------
L
T
N
A
N
---
G
V
---
P
V
T
G
L
E
Q
-
Y
A
Q
I
N
A
I
G
L
G
I
A
K
L
-----
T
P
E
S
--
G
K
G
-
Y
K
T
P
Q
W
V
S
Y
I
N
S
V
K
A
A
D
P
A
R
S
L
A
N
Y
--
S
Y
T
D
G
K
D
S
A
G
N
P
I
T
K
E
V
K
F
T
P
-----
G
D
A
--
I
Q
A
N
------
I
E
S
S
C
K
T
----
T
C
L
T
V
V
D
S
G
V
Y
R
Y
T
F
Q
T
N
L
S
T
L
-
P
A
I
E
G
L
D
L
T
Y
D
P
T
L
I
H
R
I
T
--
L
E
L
Q
T
DGS
K
D
A
K
L
V
N
S
H
I
D
F
L
P
S
D
N
F
R
V
A
K
E
T
E
T
--
R
T
V
V
D
-----
L
E
A
N
C
I
K
C
H
S
-
T
N
Y
S
D
T
S
S
T
A
K
P
L
A
L
H
G
-
G
R
R
I
G
I
A
N
C
Q
V
C
H
T
S
YSKDPETGSPLD
M
G
A
M
V
H
A
I
H
-------
K
G
T
Y
A
M
V
G
Y
S
G
T
A
----
Y
D
F
----
S
G
T
M
A
K
A
A
A
E
--------
S
G
Y
P
Q
Y
R
E
G
K
D
V
S
E
R
-
V
T
L
P
V
S
I
G
N
C
Q
S
C
H
S
T
D
D
--
K
G
P
V
D
A
A
S
F
K
H
H
K
G
L
A
------------
C
A
---
S
C
H
M
S
G
F
N
P
V
D
N
S
E
W
L
T
P
P
E
G
Q
K
D
R
G
F
V
G
N
Y
F
H
YYATPEID
G
I
P
G
V
-----
N
L
V
H
V
F
Q
N
G
G
C
A
S
C
H
A
E
Q
G
E
E
G
S
A
K
Y
H
L
A
K
A
--
N
A
T
K
L
L
R
T
E
----------
Y
A
Y
K
L
E
N
G
T
F
----
D
V
A
-----
K
G
E
L
T
F
T
V
N
W
H
S
D
V
A
P
--
H
Q
D
P
K
-
V
----
K
E
F
W
V
S
-
L
T
A
F
N
G
TEYTMGPRPSNGTLGRSEN
R
I
S
V
N
L
A
K
V
E
T
N
A
N
-
L
T
A
V
--
P
N
G
S
K
V
T
Y
T
L
T
G
I
K
A
V
I
G
T
S
S
V
P
Y
K
Q
I
V
S
I
G
K
G
F
-
M
D
---
G
K
L
L
I
C
A
N
S
A
E
L
D
P
T
M
D
A
A
I
D
C
S
N
T
E
A
P
I
Y
E
V
I
V
G
S
----
N
K
-
A
S
F
S
ADASNVTARSIVI
S
E
A
K
C
A
N
C
H
G
E
K
A
D
F
S
A
S
H
A
L
T
H
A
A
D
K
P
D
N
S
C
G
T
C
HSAVPNTAVALA
D
G
S
C
V
A
C
H
N
G
A
--
P
A
H
S
K
K
P
F
E
R
G
F
---
D
F
K
V
M
I
H
Q
I
H
A
----
D
T
R
S
V
R
R
L
TTDAATFPENPANC
A
A
C
H
D
K
GQLSL
A
T
L
G
N
K
P
A
F
L
A
S
T
G
E
Y
S
P
T
V
A
A
C
A
S
C
H
A
T
T
A
T
D
S
A
V
I
G
H
F
E
T
N
G
-
G
V
Y
N
A
A
A
G
T
Y
TPGSETCATCHGEGKSFG
V
D
K
V
H
PVKY
15
Fugue
53.92
13%
15
- C5 -
1GGX
-
RFP_DISSP
A:
[7-225]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
K
E
F
M
R
-
F
K
V
R
M
E
G
T
V
N
G
H
E
F
E
I
E
-
G
E
G
E
G
R
P
Y
----
E
G
H
-------------
N
T
V
K
L
K
V
T
-------
K
G
G
P
L
P
F
A
W
-
D
I
L
----
S
P
Q
----
F
S
K
V
Y
V
K
H
P
A
--------
D
I
--
P
D
Y
K
K
L
S
F
P
E
G
-
F
K
W
E
R
V
M
N
F
E
D
G
G
V
V
T
V
T
Q
D
S
S
L
Q
D
G
C
F
I
Y
K
V
K
F
I
G
V
NFPSDGPVMQK
K
T
---
M
-
G
W
E
A
S
T
E
R
L
Y
P
R
D
--
G
V
L
K
G
E
I
H
K
-
A
L
K
L
K
---------
D
G
G
H
Y
-----
L
V
E
F
K
S
I
Y
M
A
K
K
--
P
V
Q
L
P
G
Y
Y
Y
V
D
S
K
L
D
I
T
--
S
H
-
N
E
D
Y
T
I
----------
V
E
Q
Y
E
R
T
E
G
R
----
H
H
L
-----
F
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
36.33
32%
51
- C1 -
1RWR
-
FHAB_BORPE
A:
[217-284]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
D
G
T
A
A
G
A
M
Y
G
--
K
H
I
T
L
V
S
S
D
S
G
L
G
V
R
Q
L
G
S
L
S
S
P
S
A
I
T
V
S
S
Q
G
E
I
A
L
G
D
--------------
A
T
V
Q
R
G
-----
P
L
S
L
K
G
A
G
V
V
S
A
G
---------------------------------------------------------------------
9
HHSearch
19.20
24%
753
- C2 -
1EP5
-
POLS_EEVV8
B:
[28-44]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
F
R
P
M
H
V
----
E
G
K
I
D
N
D
V
--------------
L
--------------------------------------------------------------------------------------------
6
HHSearch
18.73
25%
395
- C6 -
3NNG
1
?
A:
[34-53]
------------------------------------------------------------------------
D
A
K
Y
G
-
A
H
L
A
I
D
G
E
I
N
T
T
W
F
-----
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
16.37
28%
250
* C7 *
2KIX
-
?
A:
[1-33]
---------------------------------------------------------------------------------------------------------------------------------------
M
L
E
P
F
Q
I
L
S
I
S
S
F
I
L
S
A
L
H
F
I
A
--
W
T
I
G
--
H
L
N
Q
------
I
K
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
4.64
21%
834
* C6 *
2LK9
-
BST2_HUMAN
A:
[22-33]
---------------------
L
L
L
G
I
G
I
L
V
L
L
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------