@TOME V3
(Feb 2022)

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3D Common Core:

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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : THIK_SALTY_: (2019-02-06 )
MRSNNNNPLTRDEILSRYFPQYRPAVATSQGLSGGSCIIAHDTHRVVLRRHHDPDAPPAHFLRHYRALSQLPASLAPRALFYTPGWMAVEYLHGVVNSALPDADELAALLYHLHQQPRFGWRIALSPLLAQYWSCCDPARRTPFWLRRLKQLQKNGEPRPLRLAPLHMDVHGDNIVLTSAGLRLIDWEYAGDGDIALELAAVWVEDERQHRQLADAYAARARIDARQLWRQIRLWHPWVIMLKAGWFEYRWRQTGEQQFIRLADETWRQLRMKG

Atome Classification :

(20 SA) -------------------------------......---...10........-----------20--------.--------.....------..30.......-.40.---------.----------......50......-..60........70.-.---.-.---....80..-.---------.....90....-.----------..-----.------------------100----..---------.--------.....110..-------..--.-------..120.-.---.--------.----.---...----.130.......-------140---------------.----------.----.-----------------......150...--.---.---..160.......170......---.-------180---.----..-..-....190.----......200...---------------------.------------.--------------------.---------------------.---------------------210-----------........-.220------...------------.--------..--...230.......240....-..-.250.-..-....260.......270..-------
(Atome) (Ident) (Tito) (Num) (QMean) (Ligand) (Uniprot) -------------------------------MRSNNN---NPLTRDEILSRYF-----------PQ--------Y--------RPAVA------TSQGLSGGSCI-IAHD---------T----------HRVVLRRHHDPDAP-PAHFLRHYRALSQLP-A---S-L---APRALFYT-P---------GWMAVEYLHGV-V----------NS-----A------------------LP-----DA---------D--------ELAALLYHLH-------QQ--P-------RFG--W-R---I--------A----L---SPL----LAQYWSCCDPA-------R-----------------R----------T----P-----------------FWLRRLKQLQKN--G---E---PRPLRLAPLHMDVHGDNIVLT---S-------A-----G----LR-LI-DWEYAGDG----DIALELAAVWVE---------------------D------------E--------------------R---------------------Q---------------------H-------------RQLADAYA-AR--------ARI------------D--------AR--QLWRQIRLWHPWVIMLKAGW-FE-YRWRQ-TG-EQQFIRLADETWRQLRMKG-------
56 HHSearch 78.6618% -16 - C3 - - 3DXQ - ? B:[3-280] ------------------------------------T---DEAR--AKLAAIP-----------ML--------AGY------TGPLE------RLGGLTNLVFR-A-----------------------GDLCLRIP---------NRANEAVAAREAAKA---G-V---SPEVLHVD-PAT-------GVMVTRYIAGAQT----------MS-----PEKFKTR------------PG-----SP---------A--------RAGEAFRKLH-------GS--G-------AVF--PFR---F--------E----L---FAM----IDDYLKVLSTK-------NVT---------------LPAG-------Y----H-----------------DVVREAGGVRSA--L---A---AHPLPLAACHCDPLCENFLDT---G-------E-----R----MW-IV-DWEYSGMN----DPLWDLGDLSVE---------------------G------------K--------------------FNAN------------------Q---------------------D-------------EELMRAYF-GG--------EA----------------------RP--AERGRVVIYKAMCDLLWTLW-GL-IQLAN-DNPVDDFRAYADGRFAR------------
54 HHSearch 78.1918% -56 - C3 - - 1NW1 - CKA2_CAEEL B:[58-398] ----------------------------------------------MLCARFL-----------GG--------AWKTVPLEHLRISR------IKGGMSNMLFL-CRLSEVYPPIRNEP----------NKVLLRVYFNPE-T-ESHLVAESVIFTLLSER---H-L---GPKLYGIF-S---------GGRLEEYIPSR-P----------LS-----CHEISL-------------AH-----MS---------T--------KIAKRVAKVH-------QL--E-------VPI--W-KEP-D--------Y----L---CEA----LQRWLKQLTGT-------VDAEHRFD----------LPEECGVSSVNC----L-----------------DLARELEFLRAH--I---S---LSKSPVTFCHNDLQEGNILLP---K-------------R----LV-LI-DFEYASYN----YRAFDFANHFIE---------------------W------------T--------------------IDYDIDEAPFYKIQTENFPENDQ---------------------M-------------LEFFLNYL-RE--------QGN------------TRENELYKKSE--DLVQETLPFVPVSHFFWGVW-GL-LQVEL-S----------------------------
55 HHSearch 77.5018% -59 - C3 - - 1NW1 - CKA2_CAEEL A:[58-398] ----------------------------------------------MLCARFL-----------GG--------AWKTVPLEHLRISR------IKGGMSNMLFL-CRLSEVYPPIRNEP----------NKVLLRVYFNPE-T-ESHLVAESVIFTLLSER---H-L---GPKLYGIF-S---------GGRLEEYIPSR-P----------LS-----CHEISL-------------AH-----MS---------T--------KIAKRVAKVH-------QL--E-------VPI--W-KEP-D--------Y----L---CEA----LQRWLKQLTGT-------VDAEHRFD----------LPEECGVSSVNC----L-----------------DLARELEFLRAH--I---S---LSKSPVTFCHNDLQEGNILLP---K-------------R----LV-LI-DFEYASYN----YRAFDFANHFIE---------------------W------------T--------------------IDYDIDEAPFYKIQTENFPENDQ---------------------M-------------LEFFLNYL-RE--------QGN------------TRENELYKKSE--DLVQETLPFVPVSHFFWGVW-GL-LQVEL-S----------------------------
74 HHSearch 75.0918% 5 - C3 - - 5UXA - ? A:[2-297] ---------------------------------SKDI---KQVI--EIAKKHN-----------LFLK------E--------ETIQF------NESGLDFQAVF-AQDNN--------G----------IDWVLRLPRRED-V-MPRTKVEKQALDLVNKYAISF-Q---APNWIIYT-E---------ELIAYKKLDGV-P----------AG-----TIDHNIGNYIWEIDINNVPEL-----FH---------K--------SLGRVLAELH-------SI--P-------SNK--A-AA--LDLVVH---T----PEEARMS----MKQRMDAVRAK------------------------------------F----G-----------------VGENLWNRWQAW--LNDDD---MWPKKTGLIHGDVHAGHTMID---KD------A-----N----VTGLI-DWTEAKVT----DVSHDFIFNYRA---------------------F------------G--------------------EE--------------------G---------------------L-------------EALILAYK-EI--------GGY------------Y--------WP--KMKEHIIELNAAYPVSIAEF-AL-----V-SG-IEEYEQMAKEAL--------------
73 HHSearch 75.0318% 6 - C3 - - 5IWU ? A:[2-297] ---------------------------------SKDI---KQVI--EIAKKHN-----------LFLK------E--------ETIQF------NESGLDFQAVF-AQDNN--------G----------IDWVLRLPRRED-V-MPRTKVEKQALDLVNKYAISF-Q---APNWIIYT-E---------ELIAYKKLDGV-P----------AG-----TIDHNIGNYIWEIDINNVPEL-----FH---------K--------SLGRVLAELH-------SI--P-------SNK--A-AA--LDLVVH---T----PEEARMS----MKQRMDAVRAK------------------------------------F----G-----------------VGENLWNRWQAW--LNDDD---MWPKKTGLIHGDVHAGHTMID---KD------A-----N----VTGLI-DWTEAKVT----DVSHDFIFNYRA---------------------F------------G--------------------EE--------------------G---------------------L-------------EALILAYK-EI--------GGY------------Y--------WP--KMKEHIIELNAAYPVSIAEF-AL-----V-SG-IEEYEQMAKEAL--------------
53 HHSearch 73.0417% -10 - C3 - - 4R78 ? A:[19-281] ---------------------------------SHME---KIIK--EKISSLL-----------SQEEE-----V--------LSVEQ------L-GGMTNQNYL-AKTT---------N----------KQYIVKFFGKGTEK-LINRQDEKYNLELLKDL---GLD---VKNYLFDIEA---------GIKVNEYIESAIT----------LD-----STSI---------------KT-----KF---------D--------KIAPILQTIH-------TS--A-------KEL--RGE---F--------A----P---FEE----IKKYESLIEEQIPY----A-----------------N----------Y----E-----------------SVRNAVFSLEKR--L---A---DLGVDRKSCHIDLVPENFIES---PQ------G-----R----LY-LI-DWEYSSMN----DPMWDLAALFLE---------------------S------------E--------------------FTSQ------------------E---------------------E-------------ETFLSHYE-SD--------Q-----------------------TP--VSHEKIAIYKILQDTIWSLW-TV-YKEEQ------------------------------
63 HHSearch 72.4717% -34 - C3 - - 3C5I ? D:[14-332] ------------------------------------P---LYIK--KICLEKV-----------PE--------WNHFTEDN-LRVKQ------IL--LTNQLFE-VGLK---------EETANNYNSIRTRVLFRIYGKHVDE-LYNTISEFEVYKTMSKY---K-I---APQLLNTF-N---------GGRIEEWLYGD-P----------LRIDDLKN------------------PT-----IL---------I--------GIANVLGKFH-------TL--S-------RKR--H-LPEHW--------DRTPCI---FKM----MEKWKNQLFKY-------KNIEKYNC----------D----------IHKYIK-----------------ESDKFIKFMKVY--SKS-D---NLANTIVFCHNDLQENNIINT---N-------K-----C----LR-LI-DFEYSGFN----FLATDIANFFIE---------------------T------------SIDYSVSSYPFFEIDKKKYISYE--------------------N---------------------R-------------KLFITAYL-SN--------YLDKVV---------PTPKL----ID--EILEAVEVQALGAHLLWGFW-SI-IRGYQ------------------------------
57 HHSearch 72.4718% -10 - C- - - 3DXQ - ? A:[3-280] ------------------------------------T---DEAR--AKLAAIP-----------ML--------AGY------TGPLE------RLGGLTNLVFR-A-----------------------GDLCLRIPGK-----YINRANEAVAAREAAKA---G-V---SPEVLHVD-PAT-------GVMVTRYIAGAQT----------MS-----PEKFKTR------------PG-----SP---------A--------RAGEAFRKLH-------GS--G-------AVF--PFR---F--------E----L---FAM----IDDYLKVLS---------NVT---------------LPAG-------Y----H-----------------DVVREAGGVRSA--L---A---AHPLPLAACHCDPLCENFLDT---G-------E-----R----MW-IV-DWEYSGMN----DPLWDLGDLSVE---------------------G------------K--------------------FNAN------------------Q---------------------D-------------EELMRAYF-GG--------EA----------------------RP--AERGRVVIYKAMCDLLWTLW-GL-IQLAN-DNPVDDFRAYADGRFAR------------
52 HHSearch 71.4517% -7 * C3 * - 4R7B - ? A:[19-281] ---------------------------------SHME---KIIK--EKISSLL-----------SQEEE-----V--------LSVEQ------L-GGMTNQNYL-AKTT---------N----------KQYIVKFFGKGTEK-LINRQDEKYNLELLKDL---GLD---VKNYLFDIEA---------GIKVNEYIESAIT----------LD-----STSI---------------KT-----KF---------D--------KIAPILQTIH-------TS--A-------KEL--RGE---F--------A----P---FEE----IKKYESLIEEQIPY----A-----------------N----------Y----E-----------------SVRNAVFSLEKR--L---A---DLGVDRKSCHIDLVPENFIES---PQ------G-----R----LY-LI-DWEYSSMN----DPMWDLAALFLE---------------------S------------E--------------------FTSQ------------------E---------------------E-------------ETFLSHYE-SD--------Q-----------------------TP--VSHEKIAIYKILQDTIWSLW-TV-YKEEQ------------------------------
61 HHSearch 71.3715% -21 - C3 - - 3CSV ? A:[4-301] ----------------------------------SRE---DEIR--DFLATHG-----------YA--------D--------WNRTP--------------RYQRLRSPT--------G----------AKAVLMDWSPE--E-GGDTQPFVDLAQYLRNL---DIS---APEIYAEE-HAR-------GLLLIEDLGDA-L----------FT-----EVINNDPAQE---------MP-----LY---------R--------AAVDLLIHLH-------DA--Q-------TPE--L-AR--L--------DPET-L---SEMTRLAFSEYRYAILGD-------A-----------------A----------E----D-----------------NRKRFEHRFAQI--L---SA--QLEGDMVFVHRDFHAQNLLWL---P-------EREGLAR----VG-VI-DFQDAKLG----HRAYDLVSLLQD---------------------A------------R--------------------RDVPAQ----------------V---------------------E-------------AQMIDHYI-QA--------TGV------------D--------ES--HFRSAYAVIAVQRNMRILGI-FA-RLSQR-FG-KRHYIEFVPRVWAHFE----------
65 HHSearch 69.8515% -54 - C3 - - 5FTG CHKA_HUMAN A:[8-351] -----------------------------------TR---RRAY--LWCKEFL-----------PGAWRGLREDE--------FHISV------IRGGLSNMLFQ-CSLP---------DTTATLGDEP-RKVLLRLYG-------EAMVLESVMFAILAER---S-L---GPKLYGIF-P---------QGRLEQFIPSR-R----------LD-----TEELSL-------------PD-----IS---------A--------EIAEKMATFH-------GM--K-------MPF--N-KE--PK-------W----L---FGT----MEKYLKEVLRI-------KFTEESRIKK--------LHKLL------S----Y-----------------NLPLELENLRSL--L---E---STPSPVVFCHNDCQEGNILLL---EGRENSEKQ-----K----LM-LI-DFEYSSYN----YRGFDIGNHFCE---------------------W------------MYDYSYEKYPFFRANIRKYPTKK--------------------Q---------------------Q-------------LHFISSYL-PA--------FQNDFENLSTEEKSII--------KE--EMLLEVNRFALASHFLWGLW-SI-VQAKI------------------------------
64 HHSearch 69.8015% -43 - C3 - - 5FUT CHKA_HUMAN A:[8-351] -----------------------------------TR---RRAY--LWCKEFL-----------PGAWRGLREDE--------FHISV------IRGGLSNMLFQ-CSLP---------DTTATLGDEP-RKVLLRLYG-----GAEAMVLESVMFAILAER---S-L---GPKLYGIF-P---------QGRLEQFIPSR-R----------LD-----TEELSL-------------PD-----IS---------A--------EIAEKMATFH-------GM--K-------MPF--N-KE--PK-------W----L---FGT----MEKYLKEVLRI-------KFTEESRIKK--------LHKLL------S----Y-----------------NLPLELENLRSL--L---E---STPSPVVFCHNDCQEGNILLL---EGRENSEKQ-----K----LM-LI-DFEYSSYN----YRGFDIGNHFCE---------------------W------------MYDYSYEKYPFFRANIRKYPTKK--------------------Q---------------------Q-------------LHFISSYL-PA--------FQNDFENLSTEEKSII--------KE--EMLLEVNRFALASHFLWGLW-SI-VQAKI------------------------------
28 Fugue 67.5515% -24 - C3 - - 1NW1 - CKA2_CAEEL A:[32-426] GMKELLSTMDLDTDANTIPELKERAHMLCARFLGGAW---KTVPLEHLRISRI-----------KG--------G--------MSNML------FLCRLSEVYPP-IRNE---------P----------NKVLLRVYFNPETE-SHLVAESVIFTLLSE-R---H-L---GPKLYGIF-S---------GGRLEEYIPSR-P----------LS-----CHEISL-------------AH-----MS---------T--------KIAKRVAKVH-------QLEVP-------IWK--E-P---D--------Y----L---CEA----LQRWLKQLTGT-------VDAEHRFDLPEECGVSSVN----------C----L-----------------DLARELEFLRAH--I---S---LSKSPVTFCHNDLQEGNILLP---K-------------R----LV-LI-DFEYASYN----YRAFDFANHFIEWTIDYDIDEAPFYKIQTENFPE------------N--------------------D---------------------Q---------------------M-------------LEFFLNYL-REQGNTRENELYK------------K--------SE--DLVQETLPFVPVSHFFWGVW-GL-LQVELSPV-GFGFADYGRDRLSLYFKHKQLLKNLA
68 HHSearch 66.5318% -18 - C3 - - 5IGI ? A:[6-300] ---------------------------------TADT---SQLY--ALAARHG-----------LK--------LH-------GPLTV------NELGLDYRIVI-ATVDD--------G----------RRWVLRIPRRAE-V-SAKVEPEARVLAMLKNRL--PFA---VPDWRVAN-AELVAYPMLEDSTA-VIQPGS-S----------TP-----DWVVPQDS-----------EV-----FA---------E--------SFATALAALH-------AV--P-------ISA--A-V---DAGMLIR--TPTQ-A---RQK----VADDVDRVRRE------------------------------------F----V-----------------VNDKRLHRWQRW--L---DDDSSWPDFSVVVHGDLYVGHVLID---NT------ER----V----SG-MI-DWSEARVD----DPAIDMAAHLMV---------------------F------------G--------------------EE--------------------G---------------------L-------------AKLLLTYE-AA--------GGR------------V--------WP--RLAHHIAERLAFGAVTYALF-AL-D-----SG-NEEYLAAAKAQLAAA-----------
42 SP3 65.6915% -17 - C3 - - 1NW1 - CKA2_CAEEL A:[32-426] -----------------------GMKELLSTMDLDTDANTIPELKERAHMLCARFLGGAWKTVPLE--------H--------LRISR------IKGGMSNMLFL-CRLS---------EVYPPIRNEP-NKVLLRVYFNPETE-SHLVAESVIFTLLSE-R---H-L---GPKLYGIF-S---------GGRLEEYIPSR-P----------LS-----C------------------HEISLAHMS---------T--------KIAKRVAKVH-------QL--E-------VPI--W-KEP-D--------Y----L---CEA----LQRWLKQLTGT-------V-----------------D----------A----EHRFDLPEECGVSSVNCLDLARELEFLRAH--I---S---LSKSPVTFCHNDLQEGNILLP-----------K-----R----LV-LI-DFEYASYN----YRAFDFANHFIE---------------------W------------T--------------------I---------------------DYDIDEAPFYKIQTENFPENDQM-------------LEFFLNYL-RE--------QGNTRENELYK----K--------SE--DLVQETLPFVPVSHFFWGVW-GL-LQVEL-SPVGFGFADYGRDRLSLYFKHKQLLKNLA
26 Fugue 65.1711% -3 - C3 - - 2QG7 - ? A:[50-458] YPITESNLRILEGEDRSEKAKELLKKYVSNVFENEKT---LYIYCKYVMLHYG-----------KD--------L--------VNPNEVDSLEFQIINGTNILIK-VKDM---------SKQ--------AKYLIRLYGPTDEI-INREREKKISCILYN-K---N-I---AKKIYVFF-T---------NGRIEEFMDGY-A----------LS-----REDIKN-------------PK-----FQ---------K--------LIAKNLKLLHDIKLNENLY--K-------ELQ--V-T---QKVPGTRPSF----L---WNT----IWKYFHLLNEE-------R-----------------K----------K----ICSFDAKANILKLIDFD-VLRDSIVEVESL--C---K---RENSPIVLCHCDLLSSNIINTVGEG-------D-----S----IS-FI-DFEYSCPM----ERAYDIANHFNE---------------------YAGFNCDWDLTPSK--------------------E---------------------E---------------------E-------------YHFIMHYLGTD--------DEE------------L--------IN--QLIREIQPFYICSHINWGLWSLL-QGMHS-FD-FINYGMTRLTASCLPIFRSKV-----
39 Fugue 65.0520% -34 - C3 - - 4WW7 BUD32_YEAST A:[4-257] -------------------------------------------EFIDKVSSYL-----------T-------------------PDVD------IAPISQGAAIV-FTTT---------T----------HPYLPRAKDSHQKY-IIKYRPRTLNESRLL-A---K-L---YLIPGLCV-P---------QLIACDPYNGF-I----------WL-----E------------------FL-----GE---------DLPGGHGFSNLKNFLWMHD-------QD--P-------Y----------------------------SDL----VATTLRKVGRQ-------I-----------------G----------L----L-----------------HWNDYC-------------------------HGDLTSSNIVLV---R-------D-----GARWTPH-LI-DF---GLG----SV-------------------------------S------------N--------------------L---------------------V---------------------E-------------DKGVDLYV-LE--------RAI------------L--------ST--HS-KHAEKYNAW---IMEGF-EEVYREQG-AK-GAKKLKEVTKRFEEVRLRGRKR----
71 HHSearch 64.9912% -1 - C- - - 3N4U - ? A:[1-299] -------------------------------MRTYTF---DQVE--KAIEQLY-----------PD--------FTI------NTIEI------SGEGNDCIAYE-I------------N----------RDFIFKFPKHSR-G-STNLFNEVNILKRIHNKL--PLP---IPEVVFTG-MPSETYQM--SFAGFTKIKGV-P----------LT-----PLLLNNLPKQSQ-------NQ-----AA---------K--------DLARFLSELH-------SI--N-------ISG--F-K---SNLVL----D----F---REK----INEDNKKIKKLLSRELKGP-----------------Q----------M----K-----------------KVDDFYRDILEN--E---I---YFKYYPCLIHNDFSSDHILFD---TEK-----N-----TI---CG-II-DFGDAAIS----DPDNDFISLMED---------------------D------------E--------------------EYGME-----------------F---------------------V-------------SKILNHYK-HK--------D-----------------------IP--TVLEKYRMKEKYWSFEKIIY-GK-EYGY------MDWYEEGLNEIRSIK----------
69 HHSearch 64.4018% -15 - C3 - - 5IGH - ? A:[6-300] ---------------------------------TADT---SQLY--ALAARHG-----------LK--------LH-------GPLTV------NELGLDYRIVI-ATVDD--------G----------RRWVLRIPRRAE-V-SAKVEPEARVLAMLKNRL--PFA---VPDWRVAN-AELVAYPMLEDSTAMVIQPGS-S----------TP-----DWVVPQDS-----------EV-----FA---------E--------SFATALAALH-------AV--P-------ISA--A-V---DAGMLIR--TPTQ-A---RQK----VADDVDRVRRE------------------------------------F----V-----------------VNDKRLHRWQRW--L---DDDSSWPDFSVVVHGDLYVGHVLID---NT------ER----V----SG-MI-DWSEARVD----DPAIDMAAHLMV---------------------F------------G--------------------EE--------------------G---------------------L-------------AKLLLTYE-AA--------GGR------------V--------WP--RLAHHIAERLAFGAVTYALF-AL-D-----SG-NEEYLAAAKAQLAAA-----------
31 Fugue 63.4415% -39 - C3 - - 3ATS Y3168_MYCTU A:[1-357] ------------------TLPAVISRWLSSVLPGGAA---PEVTVESGVDSTG-----------MS--------S--------ETIIL------TARWQQDGRSI-QQKL---------V----------ARVAPAAEDVPVFP-TYRLDHQFEVIRLVG-E---L-TDVPVPRVRWIE-TTGDVLGT--PFFLMDYVEGV-VPPDVMPYTFGDN-----W------------------FA-----DAPAERQRQLQD--------ATVAALATLH-------SI--PNAQNTFSFLTDTT-L---H--------R----H---FNW----VRSWYDFAVEGI------G-----------------R----------S----P-----------------LLERTFEWLQSHWPD---D---AAAREPVLLWGDARVGNVLYR---D-------F-----Q----PV-AVLDWEMVALGPRELDVAWMIFAHRVF---------------------Q------------E--------------------L---------------------A---------------------GLATLPGLPEVMREDDVRATYQ-AL--------TGV------------E--------LGDLHWFYVYSGVMWACVFMRTGA-RR-VHFGE-IE-KPDDVESLFYHAGLMKHLLGEEH---