@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VKB9: (2017-10-26 )
MRQGFIKAFANLVGWIFALIMGAKYAVLLAPSMSGLSQDPVVQKIAAFAFIALLIIVLTWIVTAFLNGLLKSLKLGPLNRLAGGAFGSLKGLLVVLITMQGVGPWVESSPHWKQSKFIQFLLPYAPLATELSKDAASEAFHQITSGGGVTRTSPKPMDESEETELRPDHSTKDPFY
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20..------------......30........40........50........60..--..--....70........80........90..-----......100.......110.--.....---.120.......130.----......140.......150.......160.......170....---------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------MR
Q
G
F
I
K
A
F
A
N
L
V
G
W
I
F
A
L
I
MGA------------
K
Y
A
V
L
LAPSMSGLSQ
D
P
V
V
Q
K
I
A
A
F
A
F
I
A
L
L
I
I
V
L
T
W
I
V
T
--
A
F
--
L
N
G
L
L
K
SLKLG
P
L
N
R
L
AGG
A
F
G
S
L
K
G
L
L
-----
V
V
L
I
T
MQGVGPWVESSPHW
K
--
Q
S
K
F
I
---
Q
F
L
LPYA
P
L
A
T
E
L
S
K
----
D
A
A
S
E
A
F
H
Q
ITSGGGVTRTSPKPMDESEETELRPDHSTKDPFY---------------------------------------------------------------------------------------------
20
Fugue
57.18
23%
-94
- C4 -
-
5TKZ
1
?
A:
[4-92]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
V
R
T
--
L
F
--
V
S
G
L
P
M
D
A
K
P
R
E
L
Y
L
L
F
R
G
A
R
G
-
Y
E
G
A
L
-----
L
K
M
T
S
K
N
G
-----------
K
--
P
T
S
P
V
---
G
F
V
T
F
-------
L
S
Q
----
Q
D
A
Q
D
A
R
K
M
L
Q
G
----
V
R
F
D
P
E
A
A
Q
V
L
R
L
E
L
A
K
S
N
T
K
V
--------------------------------------------------------------------------------------------------
25
Fugue
56.84
15%
-18
* C4 *
-
5B64
-
?
B:
[8-123]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
S
L
M
R
L
R
E
Q
I
V
K
A
N
L
L
V
R
E
A
S
Y
I
A
E
--
E
L
DK
R
T
E
Y
K
V
T
L
Q
I
P
T
S
S
L
D
A
N
R
K
R
G
S
L
L
S
E
P
-----
A
I
Q
V
R
R
K
G
K
G
-----
K
Q
I
W
S
--
L
E
K
L
E
---
N
R
L
L
D
M
R
D
L
Y
Q
E
W
K
E
CEED
S
P
V
S
R
S
Y
F
K
R
A
D
P
F
Y
D
E
Q
E
---------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
56.20
31%
-48
- C6 -
-
2J7O
-
?
A:
[346-431]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
L
G
D
V
P
S
A
V
Q
G
R
F
G
S
A
K
G
M
W
-----
V
I
D
V
D
D
T
G
D
E
D
W
I
E
T
Y
P
S
Q
R
KW
E
C
D
F
V
DKH
Q
R
T
L
E
V
R
S
V
A
S
E
L
----------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
55.44
31%
-49
* C6 *
-
2J7N
-
?
A:
[346-431]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
L
G
D
V
P
S
A
V
Q
G
R
F
G
S
A
K
G
M
W
-----
V
I
D
V
D
D
T
G
D
E
D
W
I
E
T
Y
P
S
Q
R
KW
E
C
D
F
V
DKH
Q
R
T
L
E
V
R
S
V
A
S
E
L
----------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
53.15
15%
14
- C2 -
-
2I46
-
ACD_HUMAN
A:
[90-241]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
R
L
V
L
R
P
W
I
R
E
L
I
L
G
S
ETPS
S
P
R
A
G
Q
LL
E
V
L
Q
D
A
E
A
A
V
A
G
P
S
H
A
P
D
T
S
D
V
G
A
T
L
L
V
S
D
G
T
H
S
V
R
C
L
V
T
--
R
E
--
A
L
D
T
S
D
----------
W
E
E
K
E
F
G
F
R
G
T
E
-----
G
R
L
L
L
L
Q
D
C
G
V
H
V
Q
V
A
E
G
G
A
--
P
A
E
F
Y
---
L
Q
V
D
R
F
S
L
L
P
T
E
Q
P
----------------------
R
L
R
V
P
G
C
N
Q
D
L
D
V
Q
K
K
L
Y
D
C
L
E
E
H
-----------------------------------------------------------------------------------------------
7
PsiBlast_PDB
49.86
68%
-1190
- C3 -
-
1QCY
-
A:
[21-36]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
--
A
F
--
L
N
D
L
L
K
R
M
D
I
G
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
45.09
11%
-38
- C1 -
-
2IQH
-
?
A:
[21-489]
NAT
E
I
R
A
S
V
G
K
M
I
D
G
I
G
R
F
Y
I
Q
M
C
T
E
L
KLS
D
Y
E
G
R
L
I
Q
N
S
L
T
I
E
R
M
V
L
S
A
F
DT
G
G
P
I
Y
R
R
V
DG
K
W
R
R
E
L
I
L
Y
D
K
E
E
I
R
R
I
W
R
Q
A
N
N
GDDA
T
A
G
L
T
H
M
M
I
W
H
S
N
L
N
D
A
T
Y
QR
T
R
A
L
V
R
T
GMDPRMCSLMQGSTLPRRSG
A
A
G
A
A
V
KG
V
G
T
M
V
M
E
L
I
R
M
I
K
R
G
I
N
R
R
T
R
I
A
Y
E
R
M
C
N
I
L
K
G
K
F
Q
T
A
------------
A
Q
R
T
M
V
D
Q
V
R
E
--
S
R
N
P
G
N
A
E
F
E
D
L
I
F
L
A
R
S
A
L
I
L
R
G
S
V
A
H
K
S
C
--
L
P
A
C
V
Y
G
S
A
V
A
S
G
Y
D
F
E
R
E
G
Y
-
S
L
V
G
I
D
-----
P
F
R
L
L
Q
---
N
S
Q
V
Y
S
L
I
R
P
N
--
E
N
P
A
H
---
K
S
Q
L
V
W
M
A
C
H
S
A
A
F
E
----
D
L
R
V
S
S
F
I
R
G
T
K
V
V
P
R
G
K
L
S
T
R
G
V
Q
I
A
S
N
E
N
M
E
T
M
E
S
S
T
L
E
L
R
SRYWAIRTRSGGNTSSGQI
S
I
Q
P
TFS
V
Q
R
N
L
P
F
D
R
P
T
I
M
AASD
M
R
T
E
I
I
R
L
M
E
S
ARPEDVSFQG
R
G
V
F
E
LSDEKAT
S
P
I
V
P
S
FDMSNEGSYFF
26
Fugue
42.22
8%
-133
- C4 -
-
2A2P
-
SELM_MOUSE
A:
[24-152]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
N
Y
R
P
D
W
N
R
L
R
G
L
------------
A
R
G
R
V
E
T
C
G
G
C
Q
L
N
R
L
K
E
V
K
A
F
V
T
E
D
I
Q
L
Y
H
N
L
V
M
K
H
L
P
G
------------------------------
A
D
P
E
-----
L
V
L
L
S
R
N
Y
Q
E
L
E
R
I
P
L
S
Q
M
T
--
R
D
E
I
N
---
A
L
V
Q
E
L
G
F
Y
R
K
S
A
P
E
----
A
Q
V
P
P
E
Y
L
W
--------
A
P
A
K
P
P
E
E
A
S
E
H
D
D
L
E
H
H
H
H
H
H
-------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
41.01
68%
-570
- C3 -
-
1PT6
-
ITA1_HUMAN
A:
[26-41]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
--
A
F
--
L
N
D
L
L
K
R
M
D
I
G
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
32.38
29%
70
- C3 -
-
3HMJ
-
FAS2_YEAST
A:
[994-1050]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
K
P
Y
K
Q
V
K
Q
I
A
P
A
E
L
E
G
L
L
DLER
V
I
V
V
T
G
F
A
E
V
G
P
W
G
S
A
R
T
R
W
E
--
M
E
A
F
G
---
E
F
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
32.38
29%
70
- C3 -
-
2VKZ
-
FAS2_YEAST
A:
[994-1047]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
K
P
Y
K
Q
V
K
Q
I
A
P
A
E
L
E
G
L
L
DLER
V
I
V
V
T
G
F
A
E
V
G
P
W
G
S
A
R
T
R
W
E
--
M
E
A
F
G
---
E
F
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
29.78
29%
124
- C3 -
-
2UV8
-
FAS2_YEAST
A:
[863-914]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
K
P
Y
K
Q
V
K
Q
I
A
P
A
E
L
E
G
L
L
DLER
V
I
V
V
T
G
F
A
E
V
G
P
W
G
S
A
R
T
R
W
E
--
M
E
A
F
G
---
E
F
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
28.53
29%
-27
- C3 -
-
2PFF
-
FAS2_YEAST
A:
[-761]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
K
P
Y
K
Q
V
K
Q
I
A
P
A
E
L
E
G
L
L
DLER
V
I
V
V
T
G
F
A
E
V
G
P
W
G
S
A
R
T
R
W
E
--
M
E
A
F
G
---
E
F
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
28.27
50%
190
- C5 -
-
1EEX
-
?
G:
[124-135]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
L
R
P
Y
R
S
T
K
E
E
-----------------------------------------------------------------------------------------------
10
HHSearch
27.68
50%
225
* C5 *
-
3AUJ
-
?
G:
[124-135]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
L
R
P
Y
R
S
T
K
E
E
-----------------------------------------------------------------------------------------------
18
Fugue
26.50
19%
39
- C3 -
-
2LV6
-
B:
[1-26]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
R
W
K
K
N
F
I
A
----
V
S
A
A
N
R
F
K
K
I
S
S
S
G
A
L
------------------------------------------------------------------------------------------------------------------------
19
Fugue
26.33
19%
39
- C3 -
-
2BBM
-
B:
[1-26]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
R
W
K
K
N
F
I
A
----
V
S
A
A
N
R
F
K
K
I
S
S
S
G
A
L
------------------------------------------------------------------------------------------------------------------------
9
HHSearch
26.03
33%
190
- C5 -
-
1IWP
-
?
M:
[92-103]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
L
R
P
F
R
S
S
Q
A
E
-----------------------------------------------------------------------------------------------
24
Fugue
21.02
32%
147
- C3 -
-
5G05
-
CDC26_HUMAN
G:
[1-25]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
R
R
K
P
T
R
L
E
L
-
K
----
L
D
D
I
E
E
F
E
N
I
R
K
D
---------------------------------------------------------------------------------------------------------------------------
17
HHSearch
18.45
21%
-261
* C3 *
-
2L9U
-
ERBB3_HUMAN
A:
[642-660]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
M
A
L
T
V
I
A
G
L
V
-----
V
I
F
M
M
L
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------