@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VMT6: (2017-11-10 )
MVAQIRIGQGMDVHAFEEGKFVTLAGVQIPHTHGLKAHSDGDVVLHALCDALLGALALGDIGQHFPDTDPEFKGADSRVLLKHVYQLILDRGYHLNNADITVACERPKLAKYNLEMRQSIADVLNVDLNQISIKATTTEKLGFTGRQEGILATATVLISH
Atome Classification :
(97 SA)
.........10.......----.20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
V
A
Q
I
RIGQGM
D
V
H
A
FEE----G
K
F
V
T
L
AGVQIPHTHGLKAHSD
G
D
V
V
L
H
A
L
C
D
A
L
L
G
A
L
A
L
G
D
I
G
QHFPDTDPEFKGA
D
S
R
V
L
L
K
H
V
Y
Q
L
I
L
DRGYHLNNA
D
I
T
V
A
CERPK
L
A
K
Y
N
L
E
M
R
Q
S
I
A
D
V
L
NVDL
N
Q
I
S
I
K
A
T
T
TEKLGFTGRQEG
I
L
A
T
A
T
V
L
ISH
137
HHSearch
91.97
59%
-148
- C8 -
-
5B8F
2
ISPF_PSEAE
C:
[7-163]
---
H
M
R
I
G
H
G
Y
D
V
H
R
F
G
E
----
G
D
F
I
T
L
G
G
V
R
I
P
H
K
H
G
L
V
A
H
S
D
G
D
V
L
L
H
A
L
S
D
A
L
L
G
A
A
A
L
G
D
I
G
K
H
F
P
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
H
V
V
A
I
V
A
E
K
G
W
K
V
G
N
V
D
A
T
I
V
A
Q
A
P
K
M
A
P
H
I
E
T
M
R
G
L
I
A
E
D
L
G
V
A
V
D
Q
V
N
V
K
A
T
T
T
E
R
L
G
F
T
G
R
E
E
G
I
A
V
H
A
V
A
L
L
M
A
21
PsiBlast_CBE
90.71
60%
-150
- C8 -
-
5B8F
2
ISPF_PSEAE
C:
[8-161]
----
M
R
I
G
H
G
Y
D
V
H
R
F
G
E
----
G
D
F
I
T
L
G
G
V
R
I
P
H
K
H
G
L
V
A
H
S
D
G
D
V
L
L
H
A
L
S
D
A
L
L
G
A
A
A
L
G
D
I
G
K
H
F
P
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
H
V
V
A
I
V
A
E
K
G
W
K
V
G
N
V
D
A
T
I
V
A
Q
A
P
K
M
A
P
H
I
E
T
M
R
G
L
I
A
E
D
L
G
V
A
V
D
Q
V
N
V
K
A
T
T
T
E
R
L
G
F
T
G
R
E
E
G
I
A
V
H
A
V
A
L
L
--
22
PsiBlast_CBE
90.53
60%
-145
- C8 -
-
5B8F
2
ISPF_PSEAE
B:
[8-161]
----
M
R
I
G
H
G
Y
D
V
H
R
F
G
E
----
G
D
F
I
T
L
G
G
V
R
I
P
H
K
H
G
L
V
A
H
S
D
G
D
V
L
L
H
A
L
S
D
A
L
L
G
A
A
A
L
G
D
I
G
K
H
F
P
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
H
V
V
A
I
V
A
E
K
G
W
K
V
G
N
V
D
A
T
I
V
A
Q
A
P
K
M
A
P
H
I
E
T
M
R
G
L
I
A
E
D
L
G
V
A
V
D
Q
V
N
V
K
A
T
T
T
E
R
L
G
F
T
G
R
E
E
G
I
A
V
H
A
V
A
L
L
--
138
HHSearch
90.08
59%
-140
* C8 *
-
5B8F
3
ISPF_PSEAE
A:
[7-163]
---
H
M
R
I
G
H
G
Y
D
V
H
R
F
G
E
----
G
D
F
I
T
L
G
G
V
R
I
P
H
K
H
G
L
V
A
H
S
D
G
D
V
L
L
H
A
L
S
D
A
L
L
G
A
A
A
L
G
D
I
G
K
H
F
P
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
H
V
V
A
I
V
A
E
K
G
W
K
V
G
N
V
D
A
T
I
V
A
Q
A
P
K
M
A
P
H
I
E
T
M
R
G
L
I
A
E
D
L
G
V
A
V
D
Q
V
N
V
K
A
T
T
T
E
R
L
G
F
T
G
R
E
E
G
I
A
V
H
A
V
A
L
L
M
A
1
PsiBlast_PDB
89.36
60%
-142
- C8 -
-
5B8F
3
ISPF_PSEAE
A:
[8-161]
----
M
R
I
G
H
G
Y
D
V
H
R
F
G
E
----
G
D
F
I
T
L
G
G
V
R
I
P
H
K
H
G
L
V
A
H
S
D
G
D
V
L
L
H
A
L
S
D
A
L
L
G
A
A
A
L
G
D
I
G
K
H
F
P
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
H
V
V
A
I
V
A
E
K
G
W
K
V
G
N
V
D
A
T
I
V
A
Q
A
P
K
M
A
P
H
I
E
T
M
R
G
L
I
A
E
D
L
G
V
A
V
D
Q
V
N
V
K
A
T
T
T
E
R
L
G
F
T
G
R
E
E
G
I
A
V
H
A
V
A
L
L
--
134
HHSearch
89.08
55%
-135
- C8 -
-
5IWY
2
ISPF_BACSU
C:
[1-157]
---
M
F
R
I
G
Q
G
F
D
V
H
Q
L
V
E
----
G
R
P
L
I
I
G
G
I
E
I
P
Y
E
K
G
L
L
G
H
S
D
A
D
V
L
L
H
T
V
A
D
A
C
L
G
A
V
G
E
G
D
I
G
K
H
F
P
D
T
D
P
E
F
K
D
A
D
S
F
K
L
L
Q
H
V
W
G
I
V
K
Q
K
G
Y
V
L
G
N
I
D
C
T
I
I
A
Q
K
P
K
M
L
P
Y
I
E
D
M
R
K
R
I
A
E
G
L
E
A
D
V
S
Q
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
A
E
G
I
A
A
Q
A
T
V
L
I
Q
K
2
PsiBlast_PDB
88.71
58%
-140
- C8 -
-
1T0A
1
ISPF_SHEON
A:
[2-157]
---
K
I
R
I
G
H
G
F
D
V
H
K
F
G
E
----
P
R
P
L
I
L
C
G
V
E
V
P
Y
E
T
G
L
V
A
H
S
D
G
D
V
V
L
H
A
I
S
D
A
I
L
G
A
M
A
L
G
D
I
G
K
H
F
P
D
T
D
A
A
Y
K
G
A
D
S
R
V
L
L
R
H
C
Y
A
L
A
K
A
K
G
F
E
L
G
N
L
D
V
T
I
I
A
Q
A
P
K
M
A
P
H
I
E
D
M
R
Q
V
L
A
A
D
L
N
A
D
V
A
D
I
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
K
E
G
I
A
V
E
A
V
V
L
L
S
-
43
PsiBlast_CBE
88.25
54%
-143
- C8 -
-
1H48
6
ISPF_ECOLI
E:
[2-156]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
23
PsiBlast_CBE
88.24
55%
-139
- C8 -
-
5IWY
1
ISPF_BACSU
F:
[2-156]
----
F
R
I
G
Q
G
F
D
V
H
Q
L
V
E
----
G
R
P
L
I
I
G
G
I
E
I
P
Y
E
K
G
L
L
G
H
S
D
A
D
V
L
L
H
T
V
A
D
A
C
L
G
A
V
G
E
G
D
I
G
K
H
F
P
D
T
D
P
E
F
K
D
A
D
S
F
K
L
L
Q
H
V
W
G
I
V
K
Q
K
G
Y
V
L
G
N
I
D
C
T
I
I
A
Q
K
P
K
M
L
P
Y
I
E
D
M
R
K
R
I
A
E
G
L
E
A
D
V
S
Q
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
A
E
G
I
A
A
Q
A
T
V
L
I
Q
-
64
PsiBlast_CBE
88.21
55%
-140
- C8 -
-
2AMT
3
ISPF_ECOLI
A:
[1-154]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
50
PsiBlast_CBE
88.21
54%
-137
- C8 -
-
1H47
3
ISPF_ECOLI
C:
[2-156]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
26
PsiBlast_CBE
88.17
55%
-139
- C8 -
-
5IWY
2
ISPF_BACSU
C:
[2-156]
----
F
R
I
G
Q
G
F
D
V
H
Q
L
V
E
----
G
R
P
L
I
I
G
G
I
E
I
P
Y
E
K
G
L
L
G
H
S
D
A
D
V
L
L
H
T
V
A
D
A
C
L
G
A
V
G
E
G
D
I
G
K
H
F
P
D
T
D
P
E
F
K
D
A
D
S
F
K
L
L
Q
H
V
W
G
I
V
K
Q
K
G
Y
V
L
G
N
I
D
C
T
I
I
A
Q
K
P
K
M
L
P
Y
I
E
D
M
R
K
R
I
A
E
G
L
E
A
D
V
S
Q
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
A
E
G
I
A
A
Q
A
T
V
L
I
Q
-
9
PsiBlast_PDB
88.10
55%
-140
- C8 -
-
3T80
6
ISPF_SALTY
A:
[4-157]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
47
PsiBlast_CBE
88.06
54%
-137
- C8 -
-
1H47
3
ISPF_ECOLI
F:
[2-156]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
4
PsiBlast_PDB
88.04
55%
-137
- C8 -
-
5IWY
2
ISPF_BACSU
A:
[2-156]
----
F
R
I
G
Q
G
F
D
V
H
Q
L
V
E
----
G
R
P
L
I
I
G
G
I
E
I
P
Y
E
K
G
L
L
G
H
S
D
A
D
V
L
L
H
T
V
A
D
A
C
L
G
A
V
G
E
G
D
I
G
K
H
F
P
D
T
D
P
E
F
K
D
A
D
S
F
K
L
L
Q
H
V
W
G
I
V
K
Q
K
G
Y
V
L
G
N
I
D
C
T
I
I
A
Q
K
P
K
M
L
P
Y
I
E
D
M
R
K
R
I
A
E
G
L
E
A
D
V
S
Q
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
A
E
G
I
A
A
Q
A
T
V
L
I
Q
-
8
PsiBlast_PDB
87.99
55%
-138
- C8 -
-
3GHZ
2
ISPF_SALTY
A:
[4-157]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
46
PsiBlast_CBE
87.86
54%
-141
- C8 -
-
1H48
4
ISPF_ECOLI
B:
[2-156]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
3
PsiBlast_PDB
87.85
55%
-138
- C8 -
-
5IWX
-
ISPF_BACSU
A:
[2-156]
----
F
R
I
G
Q
G
F
D
V
H
Q
L
V
E
----
G
R
P
L
I
I
G
G
I
E
I
P
Y
E
K
G
L
L
G
H
S
D
A
D
V
L
L
H
T
V
A
D
A
C
L
G
A
V
G
E
G
D
I
G
K
H
F
P
D
T
D
P
E
F
K
D
A
D
S
F
K
L
L
Q
H
V
W
G
I
V
K
Q
K
G
Y
V
L
G
N
I
D
C
T
I
I
A
Q
K
P
K
M
L
P
Y
I
E
D
M
R
K
R
I
A
E
G
L
E
A
D
V
S
Q
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
A
E
G
I
A
A
Q
A
T
V
L
I
Q
-
51
PsiBlast_CBE
87.73
54%
-136
- C8 -
-
1H47
4
ISPF_ECOLI
B:
[2-156]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
44
PsiBlast_CBE
87.73
54%
-139
- C8 -
-
1H48
6
ISPF_ECOLI
D:
[2-156]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
45
PsiBlast_CBE
87.71
54%
-141
- C8 -
-
1H48
4
ISPF_ECOLI
C:
[2-156]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
27
PsiBlast_CBE
87.66
55%
-139
- C8 -
-
5IWY
2
ISPF_BACSU
B:
[2-156]
----
F
R
I
G
Q
G
F
D
V
H
Q
L
V
E
----
G
R
P
L
I
I
G
G
I
E
I
P
Y
E
K
G
L
L
G
H
S
D
A
D
V
L
L
H
T
V
A
D
A
C
L
G
A
V
G
E
G
D
I
G
K
H
F
P
D
T
D
P
E
F
K
D
A
D
S
F
K
L
L
Q
H
V
W
G
I
V
K
Q
K
G
Y
V
L
G
N
I
D
C
T
I
I
A
Q
K
P
K
M
L
P
Y
I
E
D
M
R
K
R
I
A
E
G
L
E
A
D
V
S
Q
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
A
E
G
I
A
A
Q
A
T
V
L
I
Q
-
48
PsiBlast_CBE
87.65
54%
-135
- C8 -
-
1H47
3
ISPF_ECOLI
E:
[2-156]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
54
PsiBlast_CBE
87.56
54%
-140
- C8 -
-
3ERN
3
ISPF_ECOLI
D:
[6-160]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
57
PsiBlast_CBE
87.49
54%
-141
- C8 -
-
3ELC
3
ISPF_ECOLI
C:
[6-160]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
60
PsiBlast_CBE
87.42
55%
-141
- C8 -
-
2AMT
3
ISPF_ECOLI
E:
[1-154]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
123
Fugue
87.39
54%
-139
- C8 -
-
1JY8
2
ISPF_ECOLI
A:
[1-155]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
I
-
62
PsiBlast_CBE
87.32
55%
-136
- C8 -
-
2AMT
4
ISPF_ECOLI
C:
[1-154]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
18
PsiBlast_PDB
87.19
55%
-140
- C8 -
-
1JY8
2
ISPF_ECOLI
A:
[1-154]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
24
PsiBlast_CBE
87.14
55%
-148
- C8 -
-
5IWY
1
ISPF_BACSU
E:
[2-156]
----
F
R
I
G
Q
G
F
D
V
H
Q
L
V
E
----
G
R
P
L
I
I
G
G
I
E
I
P
Y
E
K
G
L
L
G
H
S
D
A
D
V
L
L
H
T
V
A
D
A
C
L
G
A
V
G
E
G
D
I
G
K
H
F
P
--------
A
D
S
F
K
L
L
Q
H
V
W
G
I
V
K
Q
K
G
Y
V
L
G
N
I
D
C
T
I
I
A
Q
K
P
K
M
L
P
Y
I
E
D
M
R
K
R
I
A
E
G
L
E
A
D
V
S
Q
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
A
E
G
I
A
A
Q
A
T
V
L
I
Q
-
15
PsiBlast_PDB
87.12
54%
-141
- C8 -
-
3ERN
3
ISPF_ECOLI
A:
[6-160]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
40
PsiBlast_CBE
87.11
55%
-136
- C8 -
-
3GHZ
2
ISPF_SALTY
C:
[4-157]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
61
PsiBlast_CBE
87.10
55%
-135
- C8 -
-
2AMT
3
ISPF_ECOLI
D:
[1-154]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
56
PsiBlast_CBE
87.05
54%
-144
- C8 -
-
3ERN
3
ISPF_ECOLI
B:
[6-160]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
58
PsiBlast_CBE
87.03
54%
-143
- C8 -
-
3ELC
3
ISPF_ECOLI
B:
[6-160]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
20
PsiBlast_PDB
86.91
55%
-141
- C8 -
-
1U3L
1
ISPF_ECOLI
A:
[1-154]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
13
PsiBlast_PDB
86.81
54%
-141
- C8 -
-
3ELC
3
ISPF_ECOLI
A:
[6-160]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
63
PsiBlast_CBE
86.78
55%
-139
- C8 -
-
2AMT
3
ISPF_ECOLI
B:
[1-154]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
42
PsiBlast_CBE
86.73
54%
-139
- C8 -
-
1H48
6
ISPF_ECOLI
F:
[2-156]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
10
PsiBlast_PDB
86.56
54%
-138
- C8 -
-
1H47
3
ISPF_ECOLI
A:
[2-156]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
11
PsiBlast_PDB
86.50
54%
-141
- C8 -
-
1H48
4
ISPF_ECOLI
A:
[2-156]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
55
PsiBlast_CBE
86.41
54%
-143
- C8 -
-
3ERN
3
ISPF_ECOLI
C:
[6-160]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
------
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
49
PsiBlast_CBE
86.25
54%
-140
- C8 -
-
1H47
3
ISPF_ECOLI
D:
[2-156]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
65
PsiBlast_CBE
86.22
55%
-137
- C8 -
-
1U43
1
ISPF_ECOLI
A:
[1-154]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
52
PsiBlast_CBE
86.01
54%
-153
- C8 -
-
3ERN
2
ISPF_ECOLI
F:
[6-160]
---
E
M
R
I
G
H
G
F
D
V
H
A
F
G
-------
P
I
I
I
G
G
V
R
I
P
Y
------
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
68
PsiBlast_CBE
85.91
53%
-135
- C8 -
-
1YQN
2
ISPF_ECOLI
A:
[1-156]
--
A
E
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
M
G
L
G
I
A
C
E
A
V
A
L
L
--
147
HHSearch
85.87
50%
-148
- C8 -
-
1W55
2
ISPDF_CAMJE
A:
[208-365]
--
F
E
I
F
T
G
N
G
F
D
V
H
E
F
G
E
----
N
R
P
L
L
L
A
G
V
Q
I
H
P
T
M
G
L
K
A
H
S
D
G
D
V
L
A
H
S
L
T
D
A
I
L
G
A
A
G
L
G
D
I
G
E
L
Y
P
D
T
D
M
K
F
K
N
A
N
S
M
E
L
L
K
Q
A
Y
D
K
V
R
E
I
G
F
E
L
I
N
I
D
I
C
V
M
A
Q
S
P
K
L
K
D
F
K
Q
A
M
Q
S
N
I
A
H
T
L
D
L
D
E
F
R
I
N
V
K
A
T
T
T
E
K
L
G
F
I
G
R
K
E
G
M
A
V
L
S
S
V
N
L
K
Y
66
PsiBlast_CBE
85.85
55%
-138
- C8 -
-
1U40
1
ISPF_ECOLI
A:
[1-154]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
59
PsiBlast_CBE
85.80
55%
-134
- C8 -
-
2AMT
3
ISPF_ECOLI
F:
[1-154]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
T
D
P
A
F
K
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
D
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
38
PsiBlast_CBE
85.29
55%
-140
- C8 -
-
3T80
5
ISPF_SALTY
C:
[4-157]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
F
P
D
------
G
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
133
HHSearch
84.34
49%
-141
- C8 -
-
3IKF
2
ISPF_BURPS
A:
[5-162]
--
M
D
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
V
R
39
PsiBlast_CBE
83.19
55%
-142
- C8 -
-
3T80
8
ISPF_SALTY
B:
[4-157]
----
M
R
I
G
H
G
F
D
V
H
A
F
G
G
----
E
G
P
I
I
I
G
G
V
R
I
P
Y
E
K
G
L
L
A
H
S
D
G
D
V
A
L
H
A
L
T
D
A
L
L
G
A
A
A
L
G
D
I
G
K
L
----------
A
D
S
R
E
L
L
R
E
A
W
R
R
I
Q
A
K
G
Y
T
L
G
N
V
D
V
T
I
I
A
Q
A
P
K
M
L
P
H
I
P
Q
M
R
V
F
I
A
E
D
L
G
C
H
M
D
E
V
N
V
K
A
T
T
T
E
K
L
G
F
T
G
R
G
E
G
I
A
C
E
A
V
A
L
L
--
107
PsiBlast_CBE
83.12
50%
-141
- C8 -
-
3F0G
1
ISPF_BURP1
A:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
132
HHSearch
83.10
41%
-149
- C8 -
-
2PMP
1
ISPF_ARATH
A:
[2-159]
--
L
P
F
R
I
G
H
G
F
D
L
H
R
L
E
P
----
G
Y
P
L
I
I
G
G
I
V
I
P
H
D
R
G
C
E
A
H
S
D
G
D
V
L
L
H
C
V
V
D
A
I
L
G
A
L
G
L
P
D
I
G
Q
I
F
P
D
S
D
P
K
W
K
G
A
A
S
S
V
F
I
K
E
A
V
R
L
M
D
E
A
G
Y
E
I
G
N
L
D
A
T
L
I
L
Q
R
P
K
I
S
P
H
K
E
T
I
R
S
N
L
S
K
L
L
G
A
D
P
S
V
V
N
L
K
A
K
T
H
E
K
V
D
S
L
G
E
N
R
S
I
A
A
H
T
V
I
L
L
M
K
92
PsiBlast_CBE
82.97
50%
-143
- C8 -
-
3K14
2
ISPF_BURP1
A:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
101
PsiBlast_CBE
82.95
50%
-146
- C8 -
-
3IEQ
2
ISPF_BURP1
A:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
69
PsiBlast_CBE
82.81
50%
-139
- C8 -
-
3QHD
2
ISPF_BURP1
C:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
76
PsiBlast_CBE
82.78
50%
-143
- C8 -
-
3P10
2
ISPF_BURP1
B:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
77
PsiBlast_CBE
82.71
50%
-140
- C8 -
-
3P10
3
ISPF_BURP1
A:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
80
PsiBlast_CBE
82.70
50%
-145
- C8 -
-
3P0Z
3
ISPF_BURP1
A:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
71
PsiBlast_CBE
82.66
50%
-143
- C8 -
-
3QHD
4
ISPF_BURP1
A:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
95
PsiBlast_CBE
82.60
50%
-142
- C8 -
-
3JVH
3
ISPF_BURP1
A:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
104
PsiBlast_CBE
82.57
50%
-139
- C8 -
-
3F0G
2
ISPF_BURP1
D:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
109
PsiBlast_CBE
82.28
50%
-137
- C8 -
-
3F0F
2
ISPF_BURP1
B:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
78
PsiBlast_CBE
82.26
50%
-147
- C8 -
-
3P0Z
2
ISPF_BURP1
C:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
------
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
110
PsiBlast_CBE
82.14
50%
-136
- C8 -
-
3F0F
1
ISPF_BURP1
A:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
106
PsiBlast_CBE
82.04
50%
-142
- C8 -
-
3F0G
2
ISPF_BURP1
B:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
--
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
--
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
73
PsiBlast_CBE
81.93
50%
-140
- C8 -
-
3Q8H
2
ISPF_BURPS
B:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
72
PsiBlast_CBE
81.85
50%
-139
- C8 -
-
3Q8H
2
ISPF_BURPS
C:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
93
PsiBlast_CBE
81.77
50%
-140
- C8 -
-
3JVH
3
ISPF_BURP1
C:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
------
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
98
PsiBlast_CBE
81.73
50%
-142
- C8 -
-
3IEW
3
ISPF_BURPS
A:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
82
PsiBlast_CBE
81.70
50%
-142
- C8 -
-
3MBM
4
ISPF_BURP1
B:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
-
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
---
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
83
PsiBlast_CBE
81.43
50%
-142
- C8 -
-
3MBM
4
ISPF_BURP1
A:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
89
PsiBlast_CBE
81.32
50%
-142
- C8 -
-
3K2X
2
ISPF_BURP1
A:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
----
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
97
PsiBlast_CBE
81.07
50%
-145
- C8 -
-
3IEW
3
ISPF_BURPS
B:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
---
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
-----
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
75
PsiBlast_CBE
80.83
50%
-142
- C8 -
-
3P10
2
ISPF_BURP1
C:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
------
F
K
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
121
PsiBlast_CBE
80.76
50%
-146
- C8 -
-
3IKF
2
ISPF_BURPS
B:
[7-160]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
---
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
--
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
91
PsiBlast_CBE
80.17
50%
-147
- C8 -
-
3K14
2
ISPF_BURP1
B:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
---
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
100
PsiBlast_CBE
80.06
50%
-142
- C8 -
-
3IEQ
2
ISPF_BURP1
B:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
---
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
F
--
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
74
PsiBlast_CBE
79.90
50%
-149
- C8 -
-
3Q8H
4
ISPF_BURPS
A:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
--------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
87
PsiBlast_CBE
79.85
50%
-146
- C8 -
-
3K2X
2
ISPF_BURP1
C:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
--
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
88
PsiBlast_CBE
79.84
50%
-144
- C8 -
-
3K2X
2
ISPF_BURP1
B:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
--
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
T
D
P
R
---
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
70
PsiBlast_CBE
79.66
50%
-141
- C8 -
-
3QHD
3
ISPF_BURP1
B:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
--------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
85
PsiBlast_CBE
79.60
50%
-142
- C8 -
-
3KE1
2
ISPF_BURP1
B:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
--
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
---------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
94
PsiBlast_CBE
79.50
50%
-137
- C8 -
-
3JVH
3
ISPF_BURP1
B:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
---------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
81
PsiBlast_CBE
79.37
50%
-136
- C8 -
-
3MBM
4
ISPF_BURP1
C:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
S
D
-------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
86
PsiBlast_CBE
79.22
50%
-147
- C8 -
-
3KE1
2
ISPF_BURP1
A:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
---------
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
90
PsiBlast_CBE
79.08
50%
-142
- C8 -
-
3K14
2
ISPF_BURP1
C:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
96
PsiBlast_CBE
78.88
50%
-145
- C8 -
-
3IEW
3
ISPF_BURPS
C:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
79
PsiBlast_CBE
78.87
50%
-145
- C8 -
-
3P0Z
3
ISPF_BURP1
B:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
--------
G
A
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
103
PsiBlast_CBE
78.79
50%
-145
- C8 -
-
3F0G
2
ISPF_BURP1
E:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
-----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
99
PsiBlast_CBE
78.60
50%
-143
- C8 -
-
3IEQ
2
ISPF_BURP1
C:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
120
PsiBlast_CBE
78.38
50%
-141
- C8 -
-
3IKF
2
ISPF_BURPS
C:
[7-160]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
84
PsiBlast_CBE
78.35
50%
-144
- C8 -
-
3KE1
2
ISPF_BURP1
C:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
--
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
102
PsiBlast_CBE
78.02
50%
-141
- C8 -
-
3F0G
2
ISPF_BURP1
F:
[24-177]
----
F
R
I
G
Q
G
Y
D
V
H
Q
L
V
P
----
G
R
P
L
I
I
G
G
V
T
I
P
Y
E
R
G
L
L
G
H
S
D
A
D
V
L
L
H
A
I
T
D
A
L
F
G
A
A
A
L
G
D
I
G
R
H
F
----------
D
S
R
A
L
L
R
E
C
A
S
R
V
A
Q
A
G
F
A
I
R
N
V
D
S
T
I
I
A
Q
A
P
K
L
A
P
H
I
D
A
M
R
A
N
I
A
A
D
L
D
L
P
L
D
R
V
N
V
K
A
K
T
N
E
K
L
G
Y
L
G
R
G
E
G
I
E
A
Q
A
A
A
L
V
--
136
HHSearch
68.89
46%
-49
- C8 -
-
3RE3
3
ISPF_FRATT
C:
[4-162]
--
M
S
F
R
I
G
H
G
Y
D
V
H
K
F
T
S
A
---
K
Q
N
I
I
I
G
G
V
E
I
A
Y
H
L
G
L
----
D
G
D
V
L
I
H
A
L
C
D
A
I
L
G
A
L
G
L
G
D
I
G
K
H
F
--------
N
I
D
S
K
F
F
L
A
E
I
K
K
M
L
D
K
K
Q
Y
S
I
S
N
I
D
C
T
I
I
A
Q
A
P
K
M
L
P
H
I
E
K
M
R
A
C
L
A
N
I
L
E
I
Q
I
S
Q
I
N
I
K
A
T
T
T
E
R
L
G
F
I
G
R
E
E
G
I
A
T
H
V
V
C
L
L
Y
R
142
HHSearch
68.36
39%
-41
- C8 -
-
4C81
1
ISPF_PLAF7
A:
[5-181]
-
Y
N
G
I
R
I
G
Q
G
Y
D
I
H
K
I
K
V
LDEE-
K
T
L
T
L
G
G
V
K
I
N
N
-
V
L
V
L
S
H
S
D
G
D
I
I
Y
H
S
I
V
D
S
I
L
G
A
L
G
S
L
D
I
G
T
L
F
P
--------
K
N
S
A
I
F
L
R
Y
A
R
L
L
I
Y
K
K
N
Y
D
I
G
N
V
D
I
N
V
I
A
Q
V
P
K
I
S
N
I
R
K
N
I
I
K
N
I
S
T
V
L
N
I
D
E
S
Q
I
S
V
K
G
K
T
H
E
K
L
G
V
I
G
E
K
K
A
I
E
C
F
A
N
I
L
L
I
P