@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VU19: (2017-12-16 )
MKKITALLFALCATVTHAELQTLDNDALQAINGQAGADLSLMLNLNQTSNGIFDNGSGGVCENVEFCHIGLAINKRFVQADTTKPSGWAENSDSGNKLWLVFKGVQGTLNIQKMGLDGADLKYLDKSNTEIIKLAIQLSFSAAQPILIRNFGFNALSIEQDNFTSSTTTQGSSANMYDYAYFKKPTYAATANSANQQVATATPSAYDYGRETGFMGLMMNGNMAIQGKVMVFSCDGSHPRC
Atome Classification :
(20 SA)
-------------------------------------.........-10.-.-..-----------....20..-------......30.-.---......40.----..---------.....50.....----------------------------..-----------.----------60.......-.70---.-........80..-...----...90........-------100-.-------------.......110-----.---------------------...----...-.120-........---------.130...-....140--------.-....-----....150.--.-....-..160-...-.....170.......180---.........190.......---200.-.......210....-------------...220....-.--...230---.-...----.....240-------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------M
K
K
I
T
A
L
L
F
-
A
L
C
-
A
-
T
V
-----------
T
H
A
E
L
Q
TL-------
D
N
D
A
L
Q
A
IN-G---QAGA
D
L
S
L
M
----
L
N
---------LNQTSNGIFDNG----------------------------SG-----------G----------VCENV
E
F
C
H
-
I
G
----
L
-
A
I
N
K
R
F
V
QADTT-KPS----GWAENSDSG
N
K
L
W
-------
L
V
--
F
-------------KGVQ
G
T
L
N
I
------
Q
---------------------
K
MG----LDG-AD---
L
K
Y
LDKSN---------
T
E
I
I
K
L
A
-
I
Q
L
SF----------S-AAQ
P
-----
I
L
I
R
NF-G--F-
N
A
L
S
-
I
EQD--NFT-SSTTTQGSSANM
Y
D
Y
A
-----
Y
FKKP
T
Y
A
ATANSANQ
Q
V
A---TA-T-P
S
A
YDYGRETG
F
M
G
-------------
L
M
MN-G
N
M
A
I
-
Q
--
G
K
V
M
-----
V
-
F
SC----DGSHPRC--------------------------------------------------------
25
Fugue
61.95
14%
12
- C5 -
-
5JUF
-
?
A:
[1-299]
---------------------MN
L
K
D
S
I
G
L
R
I
K
T
E
R
E
R
Q
Q
M
S
R
E
V
L
-
C
L
D
G
A
-
E
L
-----------
T
V
R
Q
L
I
R
I
E
K
GE
S
L
P
S
L
D
R
L
S
Y
I
A
-
K
---
R
L
G
K
S
M
T
E
L
----
L
D
QDNITIP
D
E
Y
Y
E
M
K
N
R
L
I
K
F
P
----------------------------
T
Y
-----------
R
N
P
D
R
I
K
S
K
L
T
L
I
E
E
V
Y
E
K
F
-
F
D
----
I
-
L
P
E
E
E
L
L
T
L
D
I
L
-
E
N
I
L
S
FT
S
W
E
E
S
P
K
V
E
E
I
Y
E
-------
D
L
--
F
-------------
E
Q
V
K
R
K
R
K
F
------
S
---------------------
T
N
D
----
L
L
V
-
I
D
---
Y
Y
F
F
H
L
Y
G
RKQYD
K
K
L
F
E
R
I
I
K
R
V
-
L
N
Q
E
I
W
TD-------
D
-
V
Y
N
I
-----
V
L
F
N
D
L
M
A
--
I
-
A
A
L
K
-
I
F
H
N
--
S
F
S
-
D
F
L
T
V
V
D
K
A
L
A
V
I
E
K
S
-----
Q
L
Y
S
Y
K
P
S
V
F
V
L
K
A
K
Y
E
L
L
HKE
N
K
-
K
-
E
A
A
E
N
Y
D
K
A
I
V
F
A
S
-------------
V
L
E
D
-
S
V
L
E
E
-
S
--
I
K
A
G
-----
K
-
L
A
-----
D
G
L
------------------------------------------------------------
26
Fugue
54.87
19%
27
* C8 *
-
4DVG
-
?
B:
[8-312]
-------------------------------------
E
V
V
Q
Q
K
F
A
I
-
V
A
K
-
E
M
K
I
-----------
D
N
P
E
L
I
T
I
-------
P
N
Q
W
K
L
V
Q
E
-
Y
---
E
K
K
Q
K
K
D
I
R
----
I
Q
---------
L
N
A
Q
K
T
G
N
W
R
N
A
I
TD
P
K
Y
L
A
D
L
L
K
T
RDD
M
D
L
L
N
E
M
V
V
V
F
R
S
S
-----------
S
----------
V
S
F
I
K
T
F
V
S
-
V
G
G
L
A
N
L
M
A
I
Y
K
K
K
I
E
A
E
N
S
--
N
T
----
A
I
D
E
E
R
K
C
C
E
V
L
R
-------
Y
V
--
F
-------------
A
E
E
D
A
T
V
A
L
I
E
IDG
G
V
---------------------
E
L
L
----
L
K
G
M
N
S
----
K
R
I
T
P
D
N
---------
Q
L
D
I
L
L
E
-
I
T
L
T
S
----------
S
M
V
E
H
P
SQEGL
Y
L
G
G
D
V
-
C
--
V
M
N
A
F
S
N
L
V
S
E
--
G
V
D
M
K
K
F
L
S
F
F
S
L
F
S
K
S
K
S
E
-----
K
F
K
H
A
S
L
V
L
I
N
N
L
I
D
Q
P
E
L
---
E
H
-
R
M
D
V
R
N
S
F
I
-
E
I
G
L
V
N
-------------
E
L
E
N
M
K
N
T
E
W
M
K
--
I
D
K
I
-----
K
-
D
S
I
----
N
D
F
F
D
S
W
E
E
D
K
K
E
V
E
S
R
F
D
D
L------------------------------------------
22
Fugue
52.97
15%
40
* C5 *
-
5TNV
-
?
A:
[21-326]
MYSAHTW
P
I
A
A
N
MLGFGNRAPDGGHIKDAP
A
G
V
W
A
K
Q
L
R
Q
V
R
E
L
G
F
D
H
I
D
-
P
-
T
D
-----------
A
W
V
P
L
A
A
L
-------
S
D
S
R
I
E
E
F
R
-
T
---
V
L
A
D
E
G
L
A
I
----
S
S
---------
I
S
M
T
R
S
S
I
V
D
V
E
----------------------------
N
G
-----------
E
------------
K
N
L
A
D
A
H
-
R
L
----
I
-
D
L
A
P
S
F
--
G
A
T
I
-
V
N
T
----
G
F
M
Q
A
L
T
P
E
Q
E
K
Q
-------
I
W
--
F
-------------
W
L
V
Q
G
H
V
D
-----------------------------
D
P
A
----
L
R
D
-
L
A
---
I
E
R
V
R
E
L
G
---------
D
H
A
R
T
N
G
-
I
Q
L
S
L
E
M
Y
E
DTYIGT
P
-
D
D
A
V
-----
A
F
I
K
D
V
-
D
--
H
-
D
A
V
G
-
L
N
P
D
L
G
N
L
V
-
R
L
H
R
P
M
P
H
P
S
E
M
Y
A
K
V
LPYSN
F
W
H
I
K
N
Y
S
R
D
F
D
P
A
T
G
A
-
Y
---
S
S
-
A
-
P
L
P
L
K
Y
G
Y
V
N
Y
R
Q
I
-------------
I
R
L
A
-
L
E
L
G
Y
-
T
--
G
P
F
C
-----
C
E
H
Y
G
----
S
D
S
L
G
V
C
A
E
N
R
E
Y
I
L
Q
V
L
T
S
A
L
A----------------------------------------
27
Fugue
46.42
11%
-
- C2 -
-
4U9C
-
?
A:
[41-344]
-------------------------------------
P
V
N
R
P
A
V
G
A
-
A
M
R
-
L
-
P
R
RNIASYKPDKH
Q
A
E
E
H
L
P
L
-------
K
E
K
D
I
L
F
L
D
-
G
T
L
K
E
Q
A
D
K
L
K
K
K
----
I
N
---------
E
R
Y
S
D
V
R
V
I
T
S
K
----------------------------
K
E
-----------
E
----------
E
K
Y
Q
Y
Q
F
V
R
-
A
G
----
Y
-
V
F
T
R
A
E
G
K
D
N
E
K
-
E
K
T
----
S
E
F
V
N
R
F
S
Y
D
G
F
V
-------
Y
Y
--
S
G
E
RPSQSLPS
A
G
T
V
Q
Y
S
G
N
W
Q
Y
------
M
T
D
A
K
RHRTGSTDLGYTTYYGN
E
I
G
----
A
T
S
-
Y
E
---
A
R
D
A
D
D
R
E
---------
K
H
P
A
E
Y
T
-
V
D
F
D
N
----------
K
-
T
L
N
G
-----
K
L
I
K
N
Q
---------
Y
-
V
N
P
N
--
E
P
K
-
K
P
L
T
I
Y
D
I
T
A
T
L
D
G
N
R
-----
F
T
G
S
A
K
V
S
T
E
V
K
T
Q
H
A
D
K
E
---
Y
L
F
F
-
H
T
D
A
D
Q
R
L
E
G
G
F
F
G
----------------
D
-
N
G
E
E
L
-
A
--
G
R
F
I
S
NDNS
V
-
F
G
V
----
F
A
G
K
Q
K
---------------------------------------------------------
28
Fugue
44.34
17%
22
- C8 -
-
4QVG
-
?
A:
[4-344]
-----------------------ELSAL
V
P
V
L
F
G
H
A
A
F
Q
Q
L
N
A
G
C
Q
-
L
G
L
-
F
-
E
L
-----------
L
H
E
R
G
P
L
S
-------
A
E
E
V
A
D
A
L
R
L
P
---
R
R
S
A
D
I
L
L
L
G
T
T
A
L
G
---------
L
S
T
V
T
D
G
G
Y
R
N
G
----------------------------
A
P
I
G
A
A
F
R
D
GL
W
P
V
----------
L
R
D
I
V
Q
Y
Q
D
K
I
A
----
Y
-
Q
P
A
A
D
Y
V
E
S
L
R
T
G
Q
N
A
----
G
I
R
H
F
P
G
T
T
R
D
L
Y
-------
S
R
--
L
-------------
A
A
V
P
G
L
E
E
L
------
F
---------------------
Y
R
G
----
M
H
A
--------
W
S
Q
L
S
N
---------
P
V
L
L
A
----
Q
P
D
F
----------
T
-
R
V
H
R
-----
V
L
D
V
G
G
-
G
DA
V
-
N
A
V
A
-
L
A
R
A
--
H
P
S
-
L
R
V
T
V
L
D
R
P
G
A
L
E
V
A
R
-----
K
T
I
A
E
--
A
G
L
E
E
R
V
R
T
H
A
A
---
D
I
-
F
-
T
D
S
Y
P
A
G
H
D
C
V
L
F
A
HQLVIWS
P
E
Q
N
L
T
L
L
R
K
-
A
Y
D
A
V
-
E
PG
G
R
V
L
-----
V
-
F
N
A
FTDD
D
R
T
G
P
L
Y
A
A
L
D
N
V
Y
F
T
T
LPF
R
H
S
T
IHR
W
A
D
C
E
S
W
L
R
E
A
GFTD
V
G
R
T
A
P
P
GWTP
H
G
V
V
S
G
S
R
P
R
17
HHSearch
43.25
29%
-434
* C9 *
-
3RCO
-
TDRD7_HUMAN
A:
[43-56]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
W
-----
I
P
F
K
Q
L
-
G
--
F
-
P
T
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
40.18
24%
-47
* C7 *
-
4XHL
1
HRR25_YEAST
A:
[105-244]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
M
L
A
-
L
Q
M
-
F
----------
C
-
R
I
Q
Y
-----
I
H
G
R
S
F
-
I
--
H
-
R
--
D
-
I
K
P
D
--
N
F
L
-
M
G
V
G
R
R
G
S
T
V
H
V
I
D
F
G
-----
L
S
K
K
Y
R
D
F
N
T
H
R
H
I
P
Y
R
E
N
---
K
S
-
L
-
T
G
T
A
R
Y
A
S
V
N
T
H
L
G
-------------
I
E
Q
S
-
R
R
D
D
L
-
E
S
L
G
Y
V
L
-----
I
-
Y
F
C
----
K
G
S
L
P
----------------------------------------------------------
1
PsiBlast_PDB
38.26
28%
-10
- C7 -
-
2QLT
2
GPP1_YEAST
A:
[85-201]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
------
A
---------------------
K
F
A
----
P
D
F
-
A
D
---
E
E
Y
V
N
K
L
E
---------
G
E
I
P
E
K
Y
-
G
E
H
S
I
----------
E
-
V
P
G
A
-----
V
K
L
C
N
--
A
--
L
-
N
A
L
P
-
K
E
K
W
--
A
V
A
-
T
S
G
T
-
R
D
M
A
K
K
W
F
D
I
L
-----
K
I
K
R
P
E
Y
F
I
T
A
N
D
V
K
Q
--
G
---
K
P
-
H
-
P
E
P
Y
L
K
G
R
N
G
--
L
G
-------------
F
P
I
N
-
E
Q
D
P
S
-
K
--
S
K
V
V
-----
V
-
F
E
--------------------------------------------------------------------
13
HHSearch
37.22
0%
-377
- C1 -
-
2JNA
-
?
A:
[71-79]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
-------
Y
H
--
I
-------------
I
A
A
R
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
35.44
25%
15
- C4 -
-
4PIB
3
?
A:
[53-166]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
I
G
H
K
Y
I
Y
M
S
S
D
-
D
P
R
----
G
W
S
V
--
D
P
G
N
I
T
L
NAHVG
D
T
L
S
--
F
-------------
F
C
A
S
T
S
D
N
S
------
E
---------------------
Y
A
A
F
I
YR
L
T
G
-
G
D
----
P
H
L
D
P
S
H
---------
V
E
V
I
K
L
Q
----------------
N
-
A
A
Q
P
-----
T
P
S
N
G
Y
-
P
--
F
-
T
T
A
P
-
V
A
F
S
--
S
C
D
-
A
K
V
A
Q
Q
G
Q
A
K
N
F
Y
V
W
A
----------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
32.29
11%
-174
- C7 -
-
5HB6
-
B:
[7-26]
-----------------------------------------------------
S
P
-----------
T
A
D
D
I
R
A
M
-------
N
R
M
Q
R
Q
R
V
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
29.33
13%
34
- C5 -
-
2KSM
-
ARFA_MYCTU
A:
[73-203]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
S
A
-
L
S
L
----
S
L
L
S
I
S
R
S
G
N
T
V
T
-------
L
I
G
D
F
-------------
P
D
E
A
A
K
A
A
L
------
M
---------------------
T
A
L
----
N
G
L
-
L
A
---
P
G
V
N
V
I
D
Q
---------
I
H
V
D
P
V
V
-
R
S
L
D
F
----------
S
-
S
A
E
P
-----
V
F
T
A
S
V
-
P
--
I
-
P
D
F
G
-
L
K
V
E
--
R
D
T
-
V
T
L
T
G
T
A
P
S
S
E
H
K
D
A
V
-----
K
R
A
A
T
S
T
W
P
D
M
K
I
V
N
N
I
E
V
---
T
G
-
Q
-
A
P
P
G
P
P
--------------------------------------------------------------------------------------------------------------------
16
HHSearch
27.63
20%
-237
- C9 -
-
2LH9
-
TDRD7_MOUSE
A:
[69-83]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
W
-----
I
P
F
K
Q
L
-
G
--
Y
-
P
T
L
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
26.07
33%
40
* C6 *
-
4ILM
1
CAS6B_SULSO
A:
[3-81]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
--
F
-------------
K
I
G
Y
N
V
I
P
L
------
Q
---------------------
D
V
I
----
L
P
T
-
P
S
S
K
V
L
K
Y
L
I
Q
S
G
---------
K
L
I
P
S
L
K
D
L
I
T
S
R
----------
D
-
K
Y
K
P
-----
I
F
I
S
H
L
-
G
--
F
-
N
Q
R
R
-
I
F
Q
T
--
N
----
K
T
I
T
K
G
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
25.89
31%
-22
- C9 -
-
1XC6
3
BGALA_PENSQ
A:
[642-706]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
D
T
L
P
E
A
K
N
T
Y
D
D
S
-----
A
W
T
S
A
D
H
A
Y
T
N
N
S
A
H
S
L
Q
T
---
P
T
-
S
-
L
F
A
S
D
Y
G
Y
H
T
G
--
A
-------------
L
L
F
R
-
G
H
F
T
A
-
N
--
G
K
E
K
-----
T
-
F
---------------------------------------------------------------------
6
PsiBlast_PDB
25.65
31%
-18
- C9 -
-
1TG7
3
BGALA_PENSQ
A:
[642-706]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
D
T
L
P
E
A
K
N
T
Y
D
D
S
-----
A
W
T
S
A
D
H
A
Y
T
N
N
S
A
H
S
L
Q
T
---
P
T
-
S
-
L
F
A
S
D
Y
G
Y
H
T
G
--
A
-------------
L
L
F
R
-
G
H
F
T
A
-
N
--
G
K
E
K
-----
T
-
F
---------------------------------------------------------------------
19
HHSearch
24.80
40%
-11
- C7 -
-
3N27
-
?
B:
[42-56]
---------------------------------------------------------------------------------------
Y
S
G
-
G
---
S
G
G
I
D
I
S
I
E
----
L
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
22.97
29%
146
- C6 -
-
1IHV
-
POL_HV1Z6
A:
[219-270]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
-
I
Q
N
----
F
R
V
Y
Y
R
D
S
R
D
P
V
W
K
G
P
A
K
--
L
L
--
W
-------------
K
G
-
E
G
A
V
V
I
------
Q
-----------------------------
D
N
-
S
D
---
I
K
V
V
P
R
R
K
---------
A
K
I
I
R
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
22.31
32%
-59
- C4 -
-
2WYI
2
?
A:
[747-792]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
----------
D
-
G
E
N
G
-----
V
T
I
G
N
Y
-
G
--
L
-
N
E
Y
E
-
I
L
P
D
--
T
N
T
-
I
A
I
T
L
L
R
S
V
G
E
M
G
D
W
G
-----
Y
F
P
T
P
------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
21.77
32%
-63
- C4 -
-
2WYH
-
?
A:
[747-792]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
----------
D
-
G
E
N
G
-----
V
T
I
G
N
Y
-
G
--
L
-
N
E
Y
E
-
I
L
P
D
--
T
N
T
-
I
A
I
T
L
L
R
S
V
G
E
M
G
D
W
G
-----
Y
F
P
T
P
------------------------------------------------------------------------------------------------------------------------------------------------