@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1927: (2016-03-30 )
MPEITVRAKSKTYPVYINEFALEDIREKWTKSLAKFSHVFVLTDGHVAELHKAKLDAVLADLPVVTYYVAPNGEEAKTFRVYEDVMTKMIETGLDRKAVLIAFGGGVIGDLGGFVAATYMRGIPFYQVPTTVLAHDSAVGGKVAINHPLGKNMIGNFYQPEAVIYDTQFFATLPERELRSGFAEMIKHALISDLTLLRALMDTFTEPKDFYTKDLTPFLQRGIEIKANIVAQDETEQGVRAYLNFGHTFGHALEAYGNFGKWLHGEAITYGMIYALTMSETIYGLDFDLAEFKTWLEQLGYDTTFDASVPFSKILENMRHDKKTTFNEISMVLLEEIGKPVIFKADDDLIFETYKRVMRKGGNVI
Atome Classification :
(39 SA)
.........10........20..--......30........40........50....-....60-..-------.------...--..70.........80........90..--......100.......110.......120.......130..-.-....140.......150.......160.......170.......180.......190.......200....-...--------------210------...-.....220-....------------....230.......240.......250.......260.......270.......280-----------------...-..-..290-..---......300---------......-..---------310.......320..-----..-----...330.......340..-----.-.....350.......360...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MP
E
I
T
V
R
AKSKT
Y
P
V
Y
I
N
E
F
A
L
E
--
D
I
R
E
K
W
T
K
S
L
A
KF
S
H
V
F
V
L
TD
G
H
V
A
E
L
H
K
A
K
L
-
D
A
V
L
AD-L
P
-------
V
------
V
T
Y
--
Y
VA-PNGEEA
K
T
F
R
V
Y
E
D
V
M
T
K
M
I
E
TG--LDR
K
A
V
L
I
A
FGG
G
V
I
G
D
L
G
G
F
V
A
A
T
Y
MRGIPFYQV
P
T
T
V
L
A-H-DSAVG
G
K
V
A
I
NHPLG
K
N
M
I
GNFYQP
E
A
V
I
Y
D
T
Q
F
FATL
P
E
R
E
L
R
S
G
F
A
E
M
I
K
H
A
L
I
S
D
L
T
L
L
R
A
L
M
D
TFTE-
P
K
D
--------------
F
Y
-------TK
D
-
L
T
P
F
L
Q
R--G
I
E
I
------------
K
A
N
I
V
AQD
E
T
E
Q
G
V
R
A
Y
L
N
F
G
H
T
F
G
H
A
L
E
A
YGNFGKWLHGEAI
T
Y
G
M
I
Y
A
L
T
MS
E
T
I
-----------------YGL-DF-
D
L
A
-
E
-
F
K
---
T
W
L
E
QLGY----------DTTFDA-SV---------
P
F
S
K
I
L
E
N
M
RHDKKT-----
T
F
-----
N
E
I
S
M
V
L
L
E
EIGK
P
-
V
I
F
-----K-ADD
D
L
I
F
E
T
Y
K
R
V
M
R
KGGNVI
22
PsiBlast_CBE
91.36
38%
-114
- C5 -
1XAI
3
AROB_STAAR
B:
[9-338]
---------
S
N
N
Y
P
I
Y
V
E
H
G
A
I
K
--
Y
I
----
G
T
Y
L
N
Q
F
D
Q
S
F
L
L
I
D
E
Y
V
N
Q
Y
F
A
N
K
F
-
D
D
I
L
S
--
Y
E
-------
N
------
V
H
K
--
V
I
I
-
P
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
-
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
A
T
Q
D
I
E
Q
H
F
K
D
-
R
E
I
--------------
L
Q
-------
S
L
N
G
M
D
K
Y
I
A
K
--
G
I
E
T
------------
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
Y
Y
---
H
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
-----------------
F
D
S
-
K
H
-
D
I
S
-
H
-
Y
I
---
Q
Y
L
I
Q
L
G
Y
----------
P
L
D
M
I
T
-
D
L
---------
D
F
E
T
L
Y
Q
Y
M
L
S
D
K
K
N
-----
D
K
-----
Q
G
V
Q
M
V
L
M
R
Q
F
G
D
I
-
V
V
Q
-----
H
-
V
D
-------------------
2
PsiBlast_PDB
91.12
38%
-113
- C5 -
1XAG
5
AROB_STAAR
A:
[9-338]
---------
S
N
N
Y
P
I
Y
V
E
H
G
A
I
K
--
Y
I
----
G
T
Y
L
N
Q
F
D
Q
S
F
L
L
I
D
E
Y
V
N
Q
Y
F
A
N
K
F
-
D
D
I
L
S
--
Y
E
-------
N
------
V
H
K
--
V
I
I
-
P
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
-
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
A
T
Q
D
I
E
Q
H
F
K
D
-
R
E
I
--------------
L
Q
-------
S
L
N
G
M
D
K
Y
I
A
K
--
G
I
E
T
------------
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
Y
Y
---
H
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
-----------------
F
D
S
-
K
H
-
D
I
S
-
H
-
Y
I
---
Q
Y
L
I
Q
L
G
Y
----------
P
L
D
M
I
T
-
D
L
---------
D
F
E
T
L
Y
Q
Y
M
L
S
D
K
K
N
-----
D
K
-----
Q
G
V
Q
M
V
L
M
R
Q
F
G
D
I
-
V
V
Q
-----
H
-
V
D
-------------------
1
PsiBlast_PDB
90.57
39%
-109
- C5 -
3OKF
9
AROB_VIBCH
A:
[30-373]
M
E
R
I
T
V
N
L
G
E
R
S
Y
P
I
S
I
G
A
G
L
F
A
--
N
---
P
A
L
L
S
L
S
A
K
Q
K
V
V
I
V
T
N
H
T
V
A
P
L
Y
A
P
A
I
-
I
S
L
L
D
H
-
I
G
-------
C
------
Q
H
A
--
L
L
E
L
P
D
G
E
Q
Y
K
T
L
E
T
F
N
T
V
M
S
F
L
L
E
H
N
--
Y
S
R
D
V
V
V
I
A
L
G
G
G
V
I
G
D
L
V
G
F
A
A
A
C
Y
Q
R
G
V
D
F
I
Q
I
P
T
T
L
L
S
-
Q
V
D
S
S
V
G
G
K
T
A
V
N
H
P
L
G
K
N
M
I
G
A
F
Y
Q
P
K
A
V
V
I
D
T
D
C
L
T
T
L
P
A
R
E
F
A
A
G
M
A
E
V
I
K
Y
G
I
I
Y
D
S
A
F
F
D
W
L
E
A
Q
M
E
A
-
L
Y
A
--------------
L
D
-------
E
Q
A
-
L
T
Y
A
I
A
R
--
C
C
Q
I
------------
K
A
E
V
V
A
Q
D
E
K
--
G
I
R
A
L
L
N
L
G
H
T
F
G
H
A
I
E
A
H
M
G
Y
G
N
W
L
H
G
E
A
V
S
A
G
T
V
M
A
A
K
T
A
Q
-
L
-----------------
Q
G
L
--
I
-
D
A
S
-
Q
-
F
E
R
I
L
A
I
L
K
K
A
H
L
----------
P
V
R
T
P
E
-
N
M
---------
T
F
A
D
F
M
Q
H
M
M
R
D
K
K
V
-----
L
A
-----
G
E
L
R
L
V
L
P
T
S
I
G
T
S
-
A
V
V
-----
K
----------------------
45
HHSearch
90.25
33%
-110
* C5 *
3QBE
3
AROB_MYCTU
A:
[19-367]
-------
A
V
D
P
P
Y
P
V
V
I
G
T
G
L
L
D
--
E
L
E
D
L
L
A
----
D
R
H
K
V
A
V
V
H
Q
P
G
L
A
E
-
T
A
E
E
I
-
R
K
R
L
A
G
K
G
V
-------
D
------
A
H
R
--
I
E
I
-
P
D
A
E
A
G
K
D
L
P
V
V
G
F
I
W
E
V
L
G
R
I
G
--
I
G
R
K
D
A
L
V
S
L
G
G
G
A
A
T
D
V
A
G
F
A
A
A
T
W
L
R
G
V
S
I
V
H
L
P
T
T
L
L
G
M
V
-
D
A
A
V
G
G
K
T
G
I
N
T
D
A
G
K
N
L
V
G
A
F
H
Q
P
L
A
V
L
V
D
L
A
T
L
Q
T
L
P
R
D
E
M
I
C
G
M
A
E
V
V
K
A
G
F
I
A
D
P
V
I
L
D
L
I
E
A
D
P
Q
A
-
A
L
D
--------------
P
A
-------
G
D
V
-
L
P
E
L
I
R
R
--
A
I
T
V
------------
K
A
E
V
V
A
A
----
S
E
L
R
E
I
L
N
Y
G
H
T
L
G
H
A
I
E
R
R
E
R
Y
-
R
W
R
H
G
A
A
V
S
V
G
L
V
F
A
A
E
L
A
R
L
A
-----------------
G
R
L
-
D
D
A
T
A
Q
-
R
-
H
R
---
T
I
L
S
S
L
G
L
----------
P
V
S
Y
D
P
--
D
---------
A
L
P
Q
L
L
E
I
M
A
G
D
K
K
T
-----
R
A
-----
G
V
L
R
F
V
V
L
D
G
L
A
K
P
-
G
R
M
-----
V
G
P
D
P
G
L
L
V
T
A
Y
A
G
V
C
A
------
4
PsiBlast_PDB
90.19
38%
-114
- C5 -
1XAI
3
AROB_STAAR
A:
[9-338]
---------
S
N
N
Y
P
I
Y
V
E
H
G
A
I
K
--
Y
I
----
G
T
Y
L
N
Q
F
D
Q
S
F
L
L
I
D
E
Y
V
N
Q
Y
F
A
N
K
F
-
D
D
I
L
S
--
Y
E
-------
N
------
V
H
K
--
V
I
I
-
P
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
-
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
A
T
Q
D
I
E
Q
H
F
K
D
-
R
E
I
--------------
L
Q
-------
S
L
N
G
M
D
K
Y
I
A
K
--
G
I
E
T
------------
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
Y
Y
---
H
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
-----------------
F
D
S
-
K
H
-
D
I
S
-
H
-
Y
I
---
Q
Y
L
I
Q
L
G
Y
----------
P
L
D
M
I
T
-
D
L
---------
D
F
E
T
L
Y
Q
Y
M
L
S
D
K
K
N
-----
D
K
-----
Q
G
V
Q
M
V
L
M
R
Q
F
G
D
I
-
V
V
Q
-----
H
-
V
D
-------------------
40
HHSearch
90.12
38%
-108
- C5 -
3OKF
9
AROB_VIBCH
A:
[30-389]
M
E
R
I
T
V
N
L
G
E
R
S
Y
P
I
S
I
G
A
G
L
F
A
--
N
-
P
A
L
L
S
L
S
--
A
K
Q
K
V
V
I
V
T
N
H
T
V
A
P
L
Y
A
P
A
I
-
I
S
L
L
D
H
I
G
C
-------
Q
------
H
A
L
--
L
E
L
-
P
D
G
E
Q
Y
K
T
L
E
T
F
N
T
V
M
S
F
L
L
E
H
N
--
Y
S
R
D
V
V
V
I
A
L
G
G
G
V
I
G
D
L
V
G
F
A
A
A
C
Y
Q
R
G
V
D
F
I
Q
I
P
T
T
L
L
S
Q
V
-
D
S
S
V
G
G
K
T
A
V
N
H
P
L
G
K
N
M
I
G
A
F
Y
Q
P
K
A
V
V
I
D
T
D
C
L
T
T
L
P
A
R
E
F
A
A
G
M
A
E
V
I
K
Y
G
I
I
Y
D
S
A
F
F
D
W
L
E
A
Q
M
E
A
-
L
Y
A
--------------
L
D
-------
E
Q
A
-
L
T
Y
A
I
A
R
--
C
C
Q
I
------------
K
A
E
V
V
A
Q
D
E
K
--
G
I
R
A
L
L
N
L
G
H
T
F
G
H
A
I
E
A
H
M
G
Y
G
N
W
L
H
G
E
A
V
S
A
G
T
V
M
A
A
K
T
A
Q
L
Q
-----------------
G
L
I
-
D
A
S
Q
F
E
-
R
-
I
L
---
A
I
L
K
K
A
H
L
----------
P
V
R
T
P
E
-
N
M
---------
T
F
A
D
F
M
Q
H
M
M
R
D
K
K
V
-----
L
A
-----
G
E
L
R
L
V
L
P
T
S
I
G
T
S
-
A
V
V
-----
K
G
V
P
E
A
V
I
A
Q
A
I
E
Y
C
R
T
------
3
PsiBlast_PDB
90.05
38%
-119
- C5 -
1XAH
2
AROB_STAAR
A:
[9-338]
---------
S
N
N
Y
P
I
Y
V
E
H
G
A
I
K
--
Y
I
----
G
T
Y
L
N
Q
F
D
Q
S
F
L
L
I
D
E
Y
V
N
Q
Y
F
A
N
K
F
-
D
---------------
N
------
V
H
K
--
V
I
I
-
P
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
-
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
A
T
Q
D
I
E
Q
H
F
K
D
-
R
E
I
--------------
L
Q
-------
S
L
N
G
M
D
K
Y
I
A
K
--
G
I
E
T
------------
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
Y
Y
---
H
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
-----------------
F
D
S
-
K
H
-
D
I
S
-
H
-
Y
I
---
Q
Y
L
I
Q
L
G
Y
----------
P
L
D
-------------------------------------------
G
V
Q
M
V
L
M
R
Q
F
G
D
I
-
V
V
Q
-----
H
-
V
D
-------------------
21
PsiBlast_CBE
88.83
39%
-112
- C5 -
3OKF
6
AROB_VIBCH
B:
[30-373]
M
E
R
I
T
V
N
L
G
E
R
S
Y
P
I
S
I
G
A
G
L
F
A
--
N
---
P
A
L
L
S
L
S
A
K
Q
K
V
V
I
V
T
N
H
T
V
A
P
L
Y
A
P
A
I
-
I
S
L
L
D
H
-
I
G
-------
C
------
Q
H
A
--
L
L
E
L
P
D
G
E
Q
Y
K
T
L
E
T
F
N
T
V
M
S
F
L
L
E
H
N
--
Y
S
R
D
V
V
V
I
A
L
G
G
G
V
I
G
D
L
V
G
F
A
A
A
C
Y
Q
R
G
V
D
F
I
Q
I
P
T
T
L
L
S
-
Q
V
D
S
S
V
G
G
K
T
A
V
N
H
P
L
G
K
N
M
I
G
A
F
Y
Q
P
K
A
V
V
I
D
T
D
C
L
T
T
L
P
A
R
E
F
A
A
G
M
A
E
V
I
K
Y
G
I
I
Y
D
S
A
F
F
D
W
L
E
A
Q
M
E
A
-
L
Y
A
--------------
L
D
-------
E
Q
A
-
L
T
Y
A
I
A
R
--
C
C
Q
I
------------
K
A
E
V
V
A
Q
D
E
K
E
S
G
I
R
A
L
L
N
L
G
H
T
F
G
H
A
I
E
A
H
M
G
Y
G
N
W
L
H
G
E
A
V
S
A
G
T
V
M
A
A
K
T
A
Q
-
L
-----------------
Q
G
L
--
I
-
D
A
S
-
Q
-
F
E
R
I
L
A
I
L
K
K
A
H
L
----------
P
V
R
T
P
E
-
N
M
---------
T
F
A
D
F
M
Q
H
M
M
R
--------------------
L
V
L
P
T
S
I
G
T
S
-
A
V
V
-----
K
----------------------
41
HHSearch
87.53
37%
-106
- C5 -
1XAH
2
AROB_STAAR
A:
[1-351]
-
M
K
L
Q
T
T
Y
P
S
N
N
Y
P
I
Y
V
E
H
G
A
I
K
--
Y
I
G
T
Y
L
N
Q
F
----
D
Q
S
F
L
L
I
D
E
Y
V
N
Q
Y
F
A
N
K
F
-
D
------
N
V
-------
H
--------
K
--
V
I
I
-
P
A
G
E
K
T
K
T
F
E
Q
Y
Q
E
T
L
E
Y
I
L
S
H
H
--
V
T
R
N
T
A
I
I
A
V
G
G
G
A
T
G
D
F
A
G
F
V
A
A
T
L
L
R
G
V
H
F
I
Q
V
P
T
T
I
L
A
-
H
-
D
S
S
V
G
G
K
V
G
I
N
S
K
Q
G
K
N
L
I
G
A
F
Y
R
P
T
A
V
I
Y
D
L
D
F
L
K
T
L
P
F
K
Q
I
L
S
G
Y
A
E
V
Y
K
H
A
L
L
N
G
E
S
A
T
Q
D
I
E
Q
H
F
K
D
R
E
I
L
--------------
Q
S
-------
L
N
G
-
M
D
K
Y
I
A
K
--
G
I
E
T
------------
K
L
D
I
V
V
A
D
E
K
E
Q
G
V
R
K
F
L
N
L
G
H
T
F
G
H
A
V
E
Y
Y
H
---
K
I
P
H
G
H
A
V
M
V
G
I
I
Y
Q
F
I
V
A
N
A
L
-----------------
F
-
D
-
S
K
H
D
I
S
-
H
-
Y
I
---
Q
Y
L
I
Q
L
G
Y
----------
P
L
D
-------------------------------------------
G
V
Q
M
V
L
M
R
Q
F
G
D
I
-
V
V
Q
-----
H
-
V
D
Q
L
T
L
Q
H
A
C
E
Q
L
K
T
------
44
HHSearch
84.54
32%
-103
- C5 -
1SG6
2
ARO1_EMENI
A:
[10-392]
---------
L
G
R
E
S
I
I
A
D
F
G
L
W
R
NY
V
A
K
D
L
I
S
D
C
--
S
S
T
T
Y
V
L
V
T
D
T
N
I
G
S
I
Y
T
P
S
F
-
E
E
A
F
R
K
R
A
A
-------
E
ITP
S
P
R
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
M
V
-
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
A
V
R
R
E
V
T
PGEHRFE
G
T
-------
E
E
I
-
L
K
A
R
I
L
A
--
S
A
R
H
------------
K
A
Y
V
V
S
A
-----
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
P
-
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
-----------------
G
I
L
-
K
G
V
A
V
S
-
R
-
I
V
---
K
C
L
A
A
Y
G
L
----------
P
T
S
L
K
D
A
R
I
R
K
L
T
AGKHC
S
V
D
Q
L
M
F
N
M
A
L
D
K
K
-----------------
I
V
L
L
S
A
I
G
T
P
-
Y
E
T
R
A
---
S
V
V
A
N
E
D
I
R
V
V
L
A
----------
62
Fugue
83.24
32%
-97
- C5 -
1DQS
5
ARO1_EMENI
A:
[4-391]
P
T
K
I
S
I
L
---
G
R
E
S
I
I
A
D
F
G
L
W
R
--
N
Y
V
A
K
D
L
I
S
D
C
S
S
T
T
Y
V
L
V
T
D
T
N
I
G
S
I
Y
T
P
S
F
-
E
E
A
F
R
K
-
R
A
A
EITP
S
P
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
R
RRFEGT
E
E
I
-
L
K
A
R
I
L
A
--
S
A
R
H
------------
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
P
-
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
-----------------
G
I
L
K
G
V
-
A
V
S
-
R
-
I
V
---
K
C
L
A
A
Y
G
L
PTSLKD
A
R
I
R
K
L
T
A
G
K
-
H
C
---------
S
V
D
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
-----
P
K
K
K
I
V
L
L
S
A
I
G
T
P
-
Y
E
T
-----
R
-
A
S
V
-
V
A
N
E
D
I
R
V
V
L
-------
25
PsiBlast_CBE
81.18
36%
-98
- C5 -
3ZOK
11
DHQS_ACTCH
B:
[17-364]
---
V
D
V
D
L
G
D
R
S
Y
P
I
Y
I
G
S
G
L
L
D
QP
D
L
L
Q
R
H
V
H
G
----
K
R
V
L
V
V
T
N
S
T
V
A
P
I
Y
L
D
K
V
V
G
A
L
T
N
E
-
N
P
-------
N
------
V
S
V
ES
V
I
L
-
P
D
G
E
K
Y
K
N
M
D
T
L
M
K
V
F
D
K
A
I
E
S
R
--
L
D
R
R
C
T
F
V
A
L
G
G
G
V
I
G
D
M
C
G
Y
A
A
A
S
F
L
R
G
V
N
F
I
Q
I
P
T
T
V
M
A
-
Q
V
D
S
S
V
G
G
K
T
G
I
N
H
R
L
G
K
N
L
I
G
A
F
Y
Q
P
Q
C
V
L
I
D
T
D
T
L
N
T
L
P
D
R
E
L
A
S
G
L
A
E
V
V
K
Y
G
L
I
R
D
A
N
F
F
E
W
Q
E
K
N
M
P
A
-
L
M
A
--------------
R
D
-------
P
S
A
-
L
A
Y
A
I
K
R
--
S
C
E
N
------------
K
A
E
V
V
S
L
D
E
K
E
S
G
L
R
A
T
L
N
L
G
H
T
F
G
H
A
I
E
T
G
F
G
Y
G
Q
W
L
H
G
E
A
V
A
A
G
M
V
M
A
V
D
M
S
Y
R
L
-----------------
G
W
I
-
D
E
-
S
I
V
N
R
-
A
H
---
N
I
L
Q
Q
A
K
L
----------
P
T
A
P
P
E
-
T
M
---------
T
V
E
M
F
K
S
V
M
A
V
D
K
K
V
-----
A
D
-----
G
L
L
R
L
I
L
L
K
G
P
L
G
N
-
C
V
F
-----
T
-
G
D
Y
D
-----------------
24
PsiBlast_CBE
80.90
36%
-99
- C5 -
3ZOK
10
DHQS_ACTCH
C:
[17-364]
---
V
D
V
D
L
G
D
R
S
Y
P
I
Y
I
G
S
G
L
L
D
QP
D
L
L
Q
R
H
V
H
G
----
K
R
V
L
V
V
T
N
S
T
V
A
P
I
Y
L
D
K
V
V
G
A
L
T
N
E
-
N
P
-------
N
------
V
S
V
ES
V
I
L
-
P
D
G
E
K
Y
K
N
M
D
T
L
M
K
V
F
D
K
A
I
E
S
R
--
L
D
R
R
C
T
F
V
A
L
G
G
G
V
I
G
D
M
C
G
Y
A
A
A
S
F
L
R
G
V
N
F
I
Q
I
P
T
T
V
M
A
-
Q
V
D
S
S
V
G
G
K
T
G
I
N
H
R
L
G
K
N
L
I
G
A
F
Y
Q
P
Q
C
V
L
I
D
T
D
T
L
N
T
L
P
D
R
E
L
A
S
G
L
A
E
V
V
K
Y
G
L
I
R
D
A
N
F
F
E
W
Q
E
K
N
M
P
A
-
L
M
A
--------------
R
D
-------
P
S
A
-
L
A
Y
A
I
K
R
--
S
C
E
N
------------
K
A
E
V
V
S
L
D
E
K
E
S
G
L
R
A
T
L
N
L
G
H
T
F
G
H
A
I
E
T
G
F
G
Y
G
Q
W
L
H
G
E
A
V
A
A
G
M
V
M
A
V
D
M
S
Y
R
L
-----------------
G
W
I
-
D
E
-
S
I
V
N
R
-
A
H
---
N
I
L
Q
Q
A
K
L
----------
P
T
A
P
P
E
-
T
M
---------
T
V
E
M
F
K
S
V
M
A
V
D
K
K
V
-----
A
D
-----
G
L
L
R
L
I
L
L
K
G
P
L
G
N
-
C
V
F
-----
T
-
G
D
Y
D
-----------------
5
PsiBlast_PDB
80.42
36%
-97
- C5 -
3ZOK
9
DHQS_ACTCH
A:
[17-364]
---
V
D
V
D
L
G
D
R
S
Y
P
I
Y
I
G
S
G
L
L
D
Q
P
D
L
L
Q
R
H
V
H
G
----
K
R
V
L
V
V
T
N
S
T
V
A
P
I
Y
L
D
K
V
V
G
A
L
T
N
E
-
N
P
-------
N
------
V
S
V
E
S
V
I
L
-
P
D
G
E
K
Y
K
N
M
D
T
L
M
K
V
F
D
K
A
I
E
S
R
--
L
D
R
R
C
T
F
V
A
L
G
G
G
V
I
G
D
M
C
G
Y
A
A
A
S
F
L
R
G
V
N
F
I
Q
I
P
T
T
V
M
A
-
Q
V
D
S
S
V
G
G
K
T
G
I
N
H
R
L
G
K
N
L
I
G
A
F
Y
Q
P
Q
C
V
L
I
D
T
D
T
L
N
T
L
P
D
R
E
L
A
S
G
L
A
E
V
V
K
Y
G
L
I
R
D
A
N
F
F
E
W
Q
E
K
N
M
P
A
-
L
M
A
--------------
R
D
-------
P
S
A
-
L
A
Y
A
I
K
R
--
S
C
E
N
------------
K
A
E
V
V
S
L
D
E
K
E
S
G
L
R
A
T
L
N
L
G
H
T
F
G
H
A
I
E
T
G
F
G
Y
G
Q
W
L
H
G
E
A
V
A
A
G
M
V
M
A
V
D
M
S
Y
R
L
-----------------
G
W
I
-
D
E
-
S
I
V
N
R
-
A
H
---
N
I
L
Q
Q
A
K
L
----------
P
T
A
P
P
E
-
T
M
---------
T
V
E
M
F
K
S
V
M
A
V
D
K
K
V
-----
A
D
-----
G
L
L
R
L
I
L
L
K
G
P
L
G
N
-
C
V
F
-----
T
-
G
D
Y
D
-----------------
23
PsiBlast_CBE
79.90
36%
-100
- C5 -
3ZOK
9
DHQS_ACTCH
D:
[17-364]
---
V
D
V
D
L
G
D
R
S
Y
P
I
Y
I
G
S
G
L
L
D
QP
D
L
L
Q
R
H
V
H
G
----
K
R
V
L
V
V
T
N
S
T
V
A
P
I
Y
L
D
K
V
V
G
A
L
T
N
E
-
N
P
-------
N
------
V
S
V
ES
V
I
L
-
P
D
G
E
K
Y
K
N
M
D
T
L
M
K
V
F
D
K
A
I
E
S
R
--
L
D
R
R
C
T
F
V
A
L
G
G
G
V
I
G
D
M
C
G
Y
A
A
A
S
F
L
R
G
V
N
F
I
Q
I
P
T
T
V
M
A
-
Q
V
D
S
S
V
G
G
K
T
G
I
N
H
R
L
G
K
N
L
I
G
A
F
Y
Q
P
Q
C
V
L
I
D
T
D
T
L
N
T
L
P
D
R
E
L
A
S
G
L
A
E
V
V
K
Y
G
L
I
R
D
A
N
F
F
E
W
Q
E
K
N
M
P
A
-
L
M
A
--------------
R
D
-------
P
S
A
-
L
A
Y
A
I
K
R
--
S
C
E
N
------------
K
A
E
V
V
S
L
D
E
K
E
S
G
L
R
A
T
L
N
L
G
H
T
F
G
H
A
I
E
T
G
F
G
Y
G
Q
W
L
H
G
E
A
V
A
A
G
M
V
M
A
V
D
M
S
Y
R
L
-----------------
G
W
I
-
D
E
-
S
I
V
N
R
-
A
H
---
N
I
L
Q
Q
A
K
L
----------
P
T
A
P
P
E
-
T
M
---------
T
V
E
M
F
K
S
V
M
A
V
D
K
K
V
-----
A
D
-----
G
L
L
R
L
I
L
L
K
G
P
L
G
N
-
C
V
F
-----
T
-
G
D
Y
D
-----------------
26
PsiBlast_CBE
78.79
35%
-115
- C5 -
3QBD
1
AROB_MYCTU
B:
[78-366]
------------------------------------------------------------------------------------------
P
D
A
E
A
G
K
D
L
P
V
V
G
F
I
W
E
V
L
G
R
I
G
--
I
G
R
K
D
A
L
V
S
L
G
G
G
A
A
T
D
V
A
G
F
A
A
A
T
W
L
R
G
V
S
I
V
H
L
P
T
T
L
L
G
-
M
V
D
A
A
V
G
G
K
T
G
I
N
T
D
A
G
K
N
L
V
G
A
F
H
Q
P
L
A
V
L
V
D
L
A
T
L
Q
T
L
P
R
D
E
M
I
C
G
M
A
E
V
V
K
A
G
F
I
A
D
P
V
I
L
D
L
I
E
A
D
P
Q
A
-
A
L
D
--------------
P
A
-------
G
D
V
-
L
P
E
L
I
R
R
--
A
I
T
V
------------
K
A
E
V
V
A
A
-----
E
L
R
E
I
L
N
Y
G
H
T
L
G
H
A
I
E
R
R
E
R
Y
-
R
W
R
H
G
A
A
V
S
V
G
L
V
F
A
A
E
L
A
R
L
A
-----------------
G
R
L
-
D
D
-
A
T
A
-
Q
R
H
R
---
T
I
L
S
S
L
G
L
----------
P
V
S
Y
D
P
-
D
A
----------
L
P
Q
L
L
E
I
M
A
------------------
V
L
R
F
V
V
L
D
G
L
A
K
P
G
R
M
V
-----
G
-
P
D
P
G
L
L
V
T
A
Y
A
G
V
C
-------
39
HHSearch
78.40
27%
-99
- C5 -
2GRU
8
DOIS_BACCI
A:
[2-366]
-
T
T
K
Q
I
C
F
A
D
R
C
F
N
F
A
F
G
E
H
V
L
E
--
S
V
E
S
Y
I
P
R
D
--
E
F
D
Q
Y
I
M
I
S
D
S
G
V
P
D
S
I
V
H
Y
A
-
A
E
Y
F
G
K
-
L
A
-------
P
------
V
H
I
--
L
R
F
-
Q
G
G
E
E
Y
K
T
L
S
T
V
T
N
L
Q
E
R
A
I
A
L
G
--
A
N
R
R
T
A
I
V
A
V
G
G
G
L
T
G
N
V
A
G
V
A
A
G
M
M
F
R
G
I
A
L
I
H
V
P
T
T
F
L
A
A
S
-
D
S
V
L
S
I
K
Q
A
V
N
L
T
S
G
K
N
L
V
G
F
Y
Y
P
P
R
F
V
F
A
D
T
R
I
L
S
E
S
P
P
R
Q
V
K
A
G
M
C
E
L
V
K
N
M
L
I
L
E
N
D
N
K
E
F
T
E
D
D
L
N
S
-
A
N
V
--------------
Y
S
-------
P
K
Q
-
L
E
T
F
I
N
F
--
C
I
S
A
------------
K
M
S
V
L
S
E
D
I
Y
E
K
K
K
G
L
I
F
E
Y
G
H
T
I
G
H
A
I
E
L
A
E
Q
G
-
G
I
T
H
G
E
A
I
A
V
G
M
I
Y
A
A
K
I
A
N
R
M
-----------------
N
L
M
-
P
E
H
D
V
S
-
A
-
H
Y
---
W
L
L
N
K
I
G
A
----------
L
Q
D
I
P
L
-
K
S
---------
D
P
D
S
I
F
H
Y
L
I
H
D
N
K
R
GYIKL
D
E
-----
D
N
L
G
M
I
L
L
S
G
V
G
K
P
-
A
M
Y
NQTL
L
T
P
V
R
K
T
L
I
K
E
V
I
R
E
---------
6
PsiBlast_PDB
78.33
35%
-116
- C5 -
3QBD
1
AROB_MYCTU
A:
[78-366]
------------------------------------------------------------------------------------------
P
D
A
E
A
G
K
D
L
P
V
V
G
F
I
W
E
V
L
G
R
I
G
--
I
G
R
K
D
A
L
V
S
L
G
G
G
A
A
T
D
V
A
G
F
A
A
A
T
W
L
R
G
V
S
I
V
H
L
P
T
T
L
L
G
-
M
V
D
A
A
V
G
G
K
T
G
I
N
T
D
A
G
K
N
L
V
G
A
F
H
Q
P
L
A
V
L
V
D
L
A
T
L
Q
T
L
P
R
D
E
M
I
C
G
M
A
E
V
V
K
A
G
F
I
A
D
P
V
I
L
D
L
I
E
A
D
P
Q
A
-
A
L
D
--------------
P
A
-------
G
D
V
-
L
P
E
L
I
R
R
--
A
I
T
V
------------
K
A
E
V
V
A
A
-----
E
L
R
E
I
L
N
Y
G
H
T
L
G
H
A
I
E
R
R
E
R
Y
-
R
W
R
H
G
A
A
V
S
V
G
L
V
F
A
A
E
L
A
R
L
A
-----------------
G
R
L
-
D
D
-
A
T
A
-
Q
R
H
R
---
T
I
L
S
S
L
G
L
----------
P
V
S
Y
D
P
-
D
A
----------
L
P
Q
L
L
E
I
M
A
G
-----------------
V
L
R
F
V
V
L
D
G
L
A
K
P
G
R
M
V
-----
G
-
P
D
P
G
L
L
V
T
A
Y
A
G
V
C
-------
7
PsiBlast_PDB
76.57
35%
-108
- C5 -
3QBE
3
AROB_MYCTU
A:
[78-366]
------------------------------------------------------------------------------------------
P
D
A
E
A
G
K
D
L
P
V
V
G
F
I
W
E
V
L
G
R
I
G
--
I
G
R
K
D
A
L
V
S
L
G
G
G
A
A
T
D
V
A
G
F
A
A
A
T
W
L
R
G
V
S
I
V
H
L
P
T
T
L
L
G
-
M
V
D
A
A
V
G
G
K
T
G
I
N
T
D
A
G
K
N
L
V
G
A
F
H
Q
P
L
A
V
L
V
D
L
A
T
L
Q
T
L
P
R
D
E
M
I
C
G
M
A
E
V
V
K
A
G
F
I
A
D
P
V
I
L
D
L
I
E
A
D
P
Q
A
-
A
L
D
--------------
P
A
-------
G
D
V
-
L
P
E
L
I
R
R
--
A
I
T
V
------------
K
A
E
V
V
A
A
----
S
E
L
R
E
I
L
N
Y
G
H
T
L
G
H
A
I
E
R
R
E
R
Y
-
R
W
R
H
G
A
A
V
S
V
G
L
V
F
A
A
E
L
A
R
L
A
-----------------
G
R
L
-
D
D
-
A
T
A
-
Q
R
H
R
---
T
I
L
S
S
L
G
L
----------
P
V
S
Y
D
P
-
D
A
----------
L
P
Q
L
L
E
I
M
A
G
D
K
K
T
-----
R
A
-----
G
V
L
R
F
V
V
L
D
G
L
A
K
P
G
R
M
V
-----
G
-
P
D
P
G
L
L
V
T
A
Y
A
G
V
C
-------
63
Fugue
70.09
32%
-93
- C5 -
1UJN
-
?
A:
[1-347]
M
Q
R
L
E
V
R
-
E
P
V
P
Y
P
I
L
V
G
E
G
V
L
K
--
E
V
P
P
L
A
G
P
-------
A
A
L
L
F
D
R
R
V
E
G
F
A
Q
E
V
A
-
K
A
L
G
V
R
------------------
H
L
--
L
G
L
-
P
G
G
E
A
A
K
S
L
E
V
Y
G
K
V
L
S
W
L
A
E
K
G
--
L
P
R
N
A
T
L
L
V
V
G
G
G
T
L
T
D
L
G
G
F
V
A
A
T
Y
L
R
G
V
A
Y
L
A
F
P
T
T
T
L
A
-
I
V
D
A
S
V
G
G
K
T
G
I
N
L
P
E
G
K
N
L
V
G
A
F
H
F
P
Q
G
V
Y
A
E
L
R
A
L
K
T
L
P
L
P
T
F
K
E
G
L
V
E
A
F
K
H
G
L
I
A
G
D
E
A
L
L
K
V
-----
E
-
D
L
T
--------------
P
Q
-------
S
P
R
-
L
E
A
F
L
A
R
--
A
V
A
V
------------
K
V
R
V
T
E
E
D
P
L
E
K
G
K
R
R
L
L
N
L
G
H
T
L
G
H
A
L
E
A
Q
T
R
H
-
A
L
P
H
G
M
A
V
A
Y
G
L
L
Y
A
A
L
L
G
R
A
L
-----------------
G
G
E
-
D
L
--
L
P
-
P
-
V
R
---
R
L
L
L
W
L
S
P
----------
P
P
L
--
P
-
P
L
---------
A
F
E
D
L
L
P
Y
L
S
L
H
W
V
V
-----
P
L
-----
A
P
G
R
L
V
V
R
P
-------
L
P
-----
E
-
G
L
L
R
E
A
F
A
A
W
R
E
E
L
K
G
L
G
L
L
-
27
PsiBlast_CBE
64.19
36%
-88
- C5 -
1SG6
2
ARO1_EMENI
B:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
T
P
G
E
H
R
FE
G
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
----
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
------------------
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
17
PsiBlast_PDB
64.00
36%
-85
- C5 -
1SG6
2
ARO1_EMENI
A:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
T
P
G
E
H
R
FE
G
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
-----
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
K
K
-----------------
I
V
L
L
S
A
I
G
T
P
--------------------------------
36
PsiBlast_CBE
63.17
36%
-87
- C5 -
1NRX
7
ARO1_EMENI
B:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
T
P
G
E
H
R
FE
G
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
---
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
---------------
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
10
PsiBlast_PDB
62.37
36%
-89
- C5 -
1NRX
7
ARO1_EMENI
A:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
T
P
G
-
H
R
FE
G
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
---
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
---------------
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
34
PsiBlast_CBE
62.17
36%
-88
- C5 -
1NVA
3
ARO1_EMENI
B:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
T
P
G
E
H
R
FE
G
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
---
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
K
--------
G
-----
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
12
PsiBlast_PDB
60.35
36%
-87
- C5 -
1NVA
3
ARO1_EMENI
A:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
T
P
G
E
H
R
FE
G
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
----
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
---------------
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
19
PsiBlast_PDB
57.29
30%
-85
- C5 -
2GRU
8
DOIS_BACCI
A:
[71-348]
--------------------------------------------------------------------------------------------
G
E
E
Y
K
T
L
S
T
V
T
N
L
Q
E
R
A
I
A
L
G
--
A
N
R
R
T
A
I
V
A
V
G
G
G
L
T
G
N
V
A
G
V
A
A
G
M
M
F
R
G
I
A
L
I
H
V
P
T
T
F
L
A
A
S
-
D
S
V
L
S
I
K
Q
A
V
N
L
T
S
G
K
N
L
V
G
F
Y
Y
P
P
R
F
V
F
A
D
T
R
I
L
S
E
S
P
P
R
Q
V
K
A
G
M
C
E
L
V
K
N
M
L
I
L
E
N
D
N
K
E
F
T
E
D
D
L
N
S
-
A
N
V
--------------
Y
S
-------
P
K
Q
-
L
E
T
F
I
N
F
--
C
I
S
A
------------
K
M
S
V
L
S
E
D
I
Y
E
K
K
K
G
L
I
F
E
Y
G
H
T
I
G
H
A
I
E
-
L
A
E
Q
G
G
I
T
H
G
E
A
I
A
V
G
M
I
Y
A
A
K
I
A
N
R
M
-----------------
N
L
M
P
E
H
-
D
V
S
-
A
-
H
Y
---
W
L
L
N
K
I
G
A
----------
L
Q
D
I
P
L
-
K
S
---------
D
P
D
S
I
F
H
Y
L
I
H
D
N
K
R
-----
G
Y
IKLDE
D
N
L
G
M
I
L
L
S
G
V
G
K
P
-
A
M
Y
-----
N
----------------------
18
PsiBlast_PDB
56.90
30%
-92
- C5 -
2D2X
5
DOIS_BACCI
A:
[71-348]
--------------------------------------------------------------------------------------------
G
E
E
Y
K
T
L
S
T
V
T
N
L
Q
E
R
A
I
A
L
G
--
A
N
R
R
T
A
I
V
A
V
G
G
G
L
T
G
N
V
A
G
V
A
A
G
M
M
F
R
G
I
A
L
I
H
V
P
T
T
F
L
A
A
S
-
D
S
V
L
S
I
K
Q
A
V
N
L
T
S
G
K
N
L
V
G
F
Y
Y
P
P
R
F
V
F
A
D
T
R
I
L
S
E
S
P
P
R
Q
V
K
A
G
M
C
E
L
V
K
N
M
L
I
L
----
K
E
F
T
E
D
D
L
N
S
-
A
N
V
--------------
Y
S
-------
P
K
Q
-
L
E
T
F
I
N
F
--
C
I
S
A
------------
K
M
S
V
L
S
E
D
I
Y
E
K
K
K
G
L
I
F
E
Y
G
H
T
I
G
H
A
I
E
-
L
A
E
Q
G
G
I
T
H
G
E
A
I
A
V
G
M
I
Y
A
A
K
I
A
N
R
M
-----------------
N
L
M
P
E
H
-
D
V
S
-
A
-
H
Y
---
W
L
L
N
K
I
G
A
----------
L
Q
D
I
P
L
-
K
S
---------
D
P
D
S
I
F
H
Y
L
I
H
-----------E----
D
N
L
G
M
I
L
L
S
G
V
G
K
P
-
A
M
Y
-----
N
----------------------
14
PsiBlast_PDB
56.80
36%
-73
- C5 -
1NVD
4
ARO1_EMENI
A:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
-----
R
FE
G
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
-----
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
28
PsiBlast_CBE
56.69
36%
-69
- C5 -
1NVF
5
ARO1_EMENI
C:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
T
P
G
E
H
R
FE
G
T
E
E
ILKARILASARH
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILKGVAVSRIVKCLAA
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
-----
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
29
PsiBlast_CBE
56.17
36%
-67
- C5 -
1NVF
5
ARO1_EMENI
B:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
T
P
G
E
H
R
FE
G
T
E
E
ILKARILASARH
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILKGVAVSRIVKCLAA
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
-----
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
37
PsiBlast_CBE
55.93
36%
-65
- C5 -
1NR5
5
ARO1_EMENI
B:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
T
P
G
E
H
R
FE
G
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
-----
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
32
PsiBlast_CBE
55.89
36%
-70
- C5 -
1NVD
4
ARO1_EMENI
B:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
---------
R
FE
G
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
-----
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
16
PsiBlast_PDB
55.89
36%
-68
- C5 -
1NVF
5
ARO1_EMENI
A:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
T
P
G
E
H
R
FE
G
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
-----
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
9
PsiBlast_PDB
54.71
36%
-67
- C5 -
1NR5
4
ARO1_EMENI
A:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
T
P
G
E
H
R
FE
G
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
-----
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
38
PsiBlast_CBE
53.97
36%
-67
- C5 -
1DQS
5
ARO1_EMENI
B:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
------------
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
-----
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
8
PsiBlast_PDB
53.91
36%
-67
- C5 -
1DQS
5
ARO1_EMENI
A:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
--------
R
FE
G
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
-----
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
33
PsiBlast_CBE
53.22
36%
-65
- C5 -
1NVB
2
ARO1_EMENI
B:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
T
P
G
E
H
R
FE
G
T
E
E
ILKARILASARH
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILKGVAVSRIVKCLAA
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
-----
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------
13
PsiBlast_PDB
52.35
36%
-64
- C5 -
1NVB
5
ARO1_EMENI
A:
[61-374]
-------------------------------------------------------
K
R
-
A
A
E
I
T
P
-
S
P
-------
R
------
L
L
I
--
Y
N
R
-
P
P
G
E
V
S
K
S
R
Q
T
K
A
D
I
E
D
W
M
L
S
Q
N
PP
C
G
R
D
T
V
V
I
A
L
G
G
G
V
I
G
D
L
T
G
F
V
A
S
T
Y
M
R
G
V
R
Y
V
Q
V
P
T
T
L
L
A
-
M
V
D
S
S
I
G
G
K
T
A
I
D
T
P
L
G
K
N
L
I
G
A
I
W
Q
P
T
K
I
Y
I
D
L
E
F
L
E
T
L
P
V
R
E
F
I
N
G
M
A
E
V
I
K
T
A
A
I
S
S
E
E
E
F
T
A
L
E
E
N
A
E
T
-
I
L
K
--------------
A
V
-------
R
R
E
-
V
T
P
G
E
H
R
FE
G
T
E
E
I
L
K
A
R
I
L
A
S
A
R
H
K
A
Y
V
V
S
A
D
E
R
E
G
G
L
R
N
L
L
N
W
G
H
S
I
G
H
A
I
E
A
I
L
T
-
P
Q
I
L
H
G
E
C
V
A
I
G
M
V
K
E
A
E
L
A
R
H
L
GILK
G
V
A
V
S
R
I
V
K
C
L
A
A
Y
G
L
-
P
T
-
S
L
K
-
D
-
A
R
---
I
R
K
L
T
A
G
K
----------
H
C
S
V
D
----------------
Q
L
M
F
N
M
A
L
D
K
K
N
-----
D
G
-----
P
K
K
K
I
V
L
L
S
A
I
G
T
P
--------------------------------