@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2487: (2016-04-04 )
MENERKRILELVKQGIISTEEALTLLENISKKEGKTAAKENIRRSAAPREEEQIEEETKEEPSYDYSKGWNNQGNPYTPPKSRKRRPEPTPENHERDEEEGGENSSKDREDSMRNMVNDLSQAGEKIGSFLNSAFKQVKDMPFPFLTSTKIERDFIYHDTTLSILEFEIANGNIEFKPSDSNDIKVHAMIKLFKEYPEDEALKIFFDKTTLRVDEETLRFESKSKQIVTNLTVYLPRREYDYVSVKMLNGNFHMDELSGRDLFVKTTNGNISIGTLNATLAEIESINGNVRIQNGEIRDVALKTFNGNVAVKGNYYSTNLQTKNGNVNYQLTGNEATFLKAKTGAGNIDVVVPATIGVDGRFHTNLGKLLLDLKDAEILESKTESVSKSITFTKLPNAADSSLKIEAEATTGSVKIRDVK
Atome Classification :
(19 SA)
-.........10..-------......20........30........40........50........60........70....-....80........90........100--...-......110.......120...----------....130.......140......--.150......-----.160.......170..--.-....180..-......190.......200.......210.....-..220...-----.--------...230...-----....240.-...-..-.250....-.-.-.---.260...-....270-...-.-..-..-.280...-.-.-..----.290.......300.-.-.....310--...-.....320.-....-...330..-...--..340-.......350.......360.......370.......380.......390.......400.......410.....------..420----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-M
E
N
E
R
K
R
I
L
E
L
V
K
-------
Q
GII
S
T
E
E
A
L
T
L
L
E
N
I
S
K
KEGK
T
A
A
K
E
N
I
R
RSAAPR
E
E
E
Q
I
E
E
E
TKEEPSYDYSKGWNNQGN-PYTPPKSRKRRPEPTPENHER
D
E
EE----GGE-NSSK
D
R
E
D
S
M
R
N
M
V
N
D
L
S
Q
A
G
E
----------
K
I
G
S
F
L
N
S
A
F
K
Q
V
KDMPFPFLTS--TKIE
R
D
F
I
YH-----DT
T
L
S
I
L
E
F
E
IANG
N
I
--
E
-
F
KPSDS-N
D
-
I
K
V
H
A
M
I
K
L
F
K
EYPEDE
A
L
K
I
F
F
DK
T
T
L
R
V
D
E
E
T
-LRFESKS
K
-----
Q
--------
I
V
T
N
L
T
V
Y
L
-----PRREY
D
Y
V
-
S
V
K
-
M
L-NG-NFHMD-E-L-S---G
R
D
L
F
V
K
-TTNG
N
---
I
S
I
-
G
-TL-
N
A
-
T
L
A
-
E
I
E-S-I-NG----
N
V
R
I
QNG
E
I
R
D
V
A
L
K
-T-FNG
N
V
A
V
---
K
G
N
-
Y
Y
S
T
N
L
Q
-T-KNG
N
-
V
N
Y
Q
L
TGN-
E
A
T
--
F
L
K
AK-TGAG
N
I
D
V
V
V
P
A
T
IGVDG
R
F
HT
N
L
G
K
L
L
L
DLK
D
A
E
I
L
E
S
K
T
E
S
V
SKS
I
T
FTKLPNAADS
S
L
K
I
E
A
E
ATTG
S
V
K
I
R
------DVK------
17
Fugue
67.26
16%
31
- C2 -
1OKE
4
POLG_DEN2P
A:
[1-394]
-
M
-----
R
C
I
G
I
S
N
-------
R
D
F
V
E
G
V
S
G
G
S
W
V
D
I
V
L
E
H
G
S
C
V
T
T
M
A
------------------
K
N
K
P
T
L
D
F
E
L
I
K
T
E
A
K
Q
-
P
---
A
T
L
R
K
Y
C
I
E
A
K
L
T
N
T
T
T
E
S
R
C
----
P
T
Q
-
G
E
P
T
L
N
E
E
Q
D
K
R
F
V
C
K
H
S
M
V
D
R
G
WGNGCGLF
G
K
G
G
I
V
T
C
A
M
F
T
C
K
K
N
M
E
G
K
I
V
Q
P
--
E
N
L
E
Y
T
V
V
I
T
-----
P
H
S
G
E
----
E
H
A
V
G
N
D
--
T
-
G
K
H
G
K
E
-
V
K
-
I
T
P
Q
S
--------
S
I
T
E
A
E
L
T
G
Y
G
T
V
T
M
E
C
S
P
R
T
G
L
D
F
N
E
M
V
L
-----
L
--------
Q
M
K
D
K
A
W
L
V
-----
H
R
Q
W
F
L
D
L
-
P
L
P
-
W
L
-
P
G
A
D
T
Q
G
S
-
N
-
W
-
I
---
Q
K
E
T
L
V
T
-
F
K
N
P
H
AK
K
Q
D
V
-
V
-
V
L
-
G
S
-
Q
E
G
-
A
M
H
-
T
A
L
-
T
G
----
A
T
E
I
Q
M
S
S
G
N
L
L
F
T
G
-
H
-
L
K
C
R
L
R
M
---
D
---------
K
-
L
-
Q
L
K
G
-
M
S
Y
S
M
C
T
G
-
K
F
K
--
V
V
K
E
I
-
A
E
T
Q
H
G
T
I
V
I
R
V
Q
Y
E
G
D
G
----
S
P
C
K
I
P
F
E
I
M
D
L
E
----
K
R
H
V
L
G
R
L
I
T
V
N
P
I
V
T
E
K
D
S
P
V
N
I
E
A
E
P
P
F
G
D
S
Y
I
I
I
G
VEPG
Q
L
K
L
N
W
F
K
K
5
HHSearch
65.98
18%
-73
- C5 -
3PET
11
?
A:
[8-185]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
--
K
L
I
T
R
D
Y
K
V
K
-------
E
F
N
K
I
D
A
G
T
-
V
G
N
I
--
Y
-
Y
T
Q
S
T
D
-
G
K
-
T
D
L
Q
I
Y
G
P
--
D
---------
N
I
V
A
L
I
Q
V
A
V
K
D
N
T
-
L
F
L
S
I
D
K
S
KKVRN
F
--------
K
K
M
K
I
T
I
T
S
-----
P
T
--
L
N
G
I
-
S
F
K
--
G
-
V
G
-
D
V
H
I
E
N
G
-
L
-
T
---
T
D
N
L
D
I
E
S
K
G
V
G
N
---
V
D
I
-
Q
-
S
L
-
T
C
-
Q
K
L
-
N
V
Q
-
S
M
G
-
V
G
----
D
V
K
L
E
G
T
-
A
Q
I
A
A
L
H
-
S
K
G
V
G
N
I
E
A
---
G
N
L
R
A
N
A
V
E
A
S
S
Q
-
G
V
G
D
-
I
T
C
N
A
---------------------------------------------------------------------------------------------------------
15
Fugue
57.89
20%
-21
* C5 *
4QRK
2
?
A:
[9-220]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
K
E
E
-
I
K
I
V
E
P
N
G
-----
A
--------
E
K
T
K
L
N
L
N
F
-----
G
V
G
K
L
N
I
S
G
N
E
E
-
K
L
M
K
G
-
K
F
I
Y
S
-
E
-
N
-
E
WK
P
E
I
K
Y
E
V
K
-
D
K
D
G
E
---
L
E
I
-
S
-
Q
P
-
G
L
-
K
S
G
-
N
V
S
-
L
-
N
-
N
K
R
N
E
W
N
I
N
L
N
E
K
I
P
T
E
I
K
L
S
-
L
-
G
T
G
E
F
K
A
DLS
K
I
N
-
L
K
E
L
N
V
G
M
G
-
V
-
G
K
-
V
D
L
D
I
S
G
N
-
Y
K
N
N
V
K
V
N
I
E
-
G
G
V
G
E
A
T
V
Y
L
P
K
S
I
G
V
K
I
K
A
E
K
G
V
G
A
V
N
-----
A
N
G
F
I
V
E
G
E
N
I
Y
K
N
S
Q
Y
G
K
S
K
N
----
S
I
E
V
N
I
E
A
G
V
G
A
I
N
I
K
------
Q
K
-------
7
HHSearch
52.62
22%
-45
- C5 -
3PET
7
?
A:
[90-204]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
G
I
S
F
--
K
G
V
G
D
---
V
H
I
-
E
N
G
L
-
T
T
-
D
N
L
-
D
I
E
S
K
-
G
-
V
G
----
N
V
D
I
Q
S
L
T
C
Q
K
L
N
V
Q
-
S
M
G
V
G
D
V
K
L
---
E
G
T
-
A
Q
I
A
A
L
H
-
S
K
G
V
G
N
-
I
E
A
G
N
L
---
R
A
N
--
A
V
E
A
S
S
Q
G
V
G
D
I
T
C
N
A
T
E
S
I
--
D
A
A
V
-
R
G
V
G
S
I
K
Y
K
G
S
----------------------------------------------------------
4
HHSearch
41.15
14%
19
- C5 -
3LYC
-
?
A:
[27-249]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
G
--
N
I
T
T
E
N
I
P
V
S
-------
E
Y
D
C
L
E
L
E
G
G
G
M
V
V
--
N
-
Y
T
Q
S
D
A
P
E
G
-
L
E
I
K
T
D
R
-------------
N
I
F
E
K
Y
E
F
N
V
E
N
H
K
-
L
K
I
R
P
K
K
E
-----
F
RKHTNFRP
T
E
F
M
V
T
A
N
S
-----
R
N
--
L
K
K
L
-
A
A
--
A
G
-
S
T
-
H
V
N
I
N
-
S
P
L
-
Q
---
A
E
E
F
E
A
G
L
A
G
S
G
I
---
I
Q
F
-
H
-
D
T
A
S
F
-
T
N
L
-
K
I
E
I
A
-
G
-
S
G
----
D
F
V
G
H
K
V
Y
C
E
E
L
N
G
D
M
A
-
G
S
N
T
I
V
L
---
G
G
T
-
V
G
I
A
E
F
S
I
A
-
G
S
G
T
-
V
R
A
F
D
C
---
T
M
D
--
E
L
E
C
K
I
A
G
S
G
D
I
E
A
F
V
V
N
K
I
--
K
A
E
I
-
A
G
S
G
S
V
K
Y
K
G
D
P
---------------------------------------------------------
18
Fugue
39.36
22%
58
- C3 -
4H3W
-
?
A:
[38-350]
---------------------------------------------------------------------------
E
S
W
V
A
P
L
G
M
G
Y
V
T
--
S
D
D
V
V
N
V
E
V
P
S
I
R
E
V
D
G
A
Y
V
M
I
Y
D
G
E
M
I
G
S
L
R
A
A
S
D
V
E
I
A
S
E
D
I
T
--
T
G
----------
D
I
D
G
L
F
D
G
D
F
V
L
A
L
T
N
P
H
I
T
L
S
N
VN
A
S
L
D
C
S
L
S
I
E
A
E
N
TS
E
A
T
S
S
D
F
T
L
S
T
V
S
P
N
I
--
W
-
I
G
P
L
D
P
-
T
D
A
F
F
V
N
E
L
P
G
I
V
Q
I
V
P
Q
I
--------
H
L
S
L
S
A
D
S
Q
----
W
T
N
A
P
A
-----
D
--------
A
L
S
E
L
R
Y
A
V
E
L
P
LT
P
A
P
E
F
S
A
V
-
S
V
E
-
R
I
-
E
D
-
A
F
--
D
-
E
-
D
-
F
---
V
D
Y
I
F
----
S
D
G
S
---
A
R
I
Y
G
-
E
V
T
N
E
M
P
F
D
M
S
I
E
M
V
-
I
M
D
E
----
N
--------------------
N
V
P
V
---
D
I
Q
-
F
P
A
Q
E
V
--
G
-
Q
S
G
E
-
V
I
F
E
I
T
E
D
M
P
M
----------
D
A
R
H
I
D
L
N
L
H
L
T
G
R
D
Q
G
E
---
A
L
G
Q
T
T
F
N
L
L
E
G
G
I
------------------------------------------------------
8
HHSearch
35.93
26%
35
- C4 -
1NVP
-
T2AG_HUMAN
D:
[18-44]
--------
L
D
E
L
I
Q
-------
S
Q
Q
I
T
P
Q
L
A
L
Q
V
L
L
Q
F
D
K
A
I
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
35.68
18%
12
- C1 -
2COV
-
3XYN_ALCSP
D:
[378-469]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
P
E
-
N
C
-
Q
D
-
D
F
N
F
N
-
Y
-
V
-
S
---
D
Q
E
I
E
V
Y
-
H
V
D
K
G
---
W
S
A
-
G
-
W
N
-
Y
V
-
C
L
-----------
N
----
D
Y
C
L
P
G
N
K
S
N
G
A
F
R
K
-
T
-
F
N
---
A
V
---
L
G
Q
-
D
Y
K
L
T
F
K
-
V
-
E
D
R
Y
G
Q
G
Q
Q
I
L
D
R
-
N
I
T
--
F
T
T
Q
V
-
C
N
----------------------------------------------------------------------------------------
10
HHSearch
34.65
26%
46
- C4 -
1NH2
-
T2AG_YEAST
D:
[22-61]
--------
L
D
T
L
I
S
-------
D
G
R
I
E
A
S
L
A
M
R
V
L
E
T
F
D
K
V
V
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
30.97
30%
10
* C6 *
1ZGR
-
LEC_PARPC
A:
[165-219]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
A
F
N
F
K
V
G
--
S
W
I
K
D
I
I
I
Y
A
-----
D
A
A
I
N
S
I
A
F
K
D
A
N
G
H
C
YG
K
-
F
G
G
Q
D
P
-
N
D
-
I
G
V
E
K
K
V
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
30.46
30%
22
- C6 -
1ZGS
1
LEC_PARPC
A:
[165-219]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
A
F
N
F
K
V
G
--
S
W
I
K
D
I
I
I
Y
A
-----
D
A
A
I
N
S
I
A
F
K
D
A
N
G
H
C
YG
K
-
F
G
G
Q
D
P
-
N
D
-
I
G
V
E
K
K
V
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
27.93
35%
46
- C6 -
4MQ0
1
?
A:
[165-214]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
D
A
F
N
F
K
V
G
--
S
W
I
K
D
I
I
V
Y
A
-----
D
A
T
I
N
S
I
A
F
K
D
A
D
G
H
C
--
E
K
F
G
G
Q
D
P
-
N
D
-
I
G
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
27.81
20%
110
- C4 -
2CKZ
-
RPC9_YEAST
A:
[1-68]
------
M
K
V
L
E
-
E
R
-------
N
A
F
L
S
D
Y
E
V
L
K
F
L
T
D
L
E
K
K
H
L
W
D
Q
K
S
L
A
A
L
R
P
Y
N
H
P
E
L
Q
G
I
T
R
N
V
V
N
Y
L
S
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
25.45
8%
16
- C5 -
3LYC
-
?
A:
[132-250]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
E
F
-
E
A
G
L
A
G
-
S
G
-
I
I
Q
F
H
-
D
-
T
A
S
---
F
T
N
L
K
I
E
I
A
G
S
G
D
---
F
V
G
-
H
-
K
V
-
Y
C
-
E
E
L
-
N
G
D
M
A
-
G
-
S
N
----
T
I
V
L
G
G
T
-
V
G
I
A
E
F
S
I
A
-
G
S
G
T
V
R
A
---
F
D
C
T
M
D
E
L
E
C
K
I
A
-
G
S
G
D
-
I
E
A
F
V
V
N
---
K
I
--
K
A
E
I
--
A
G
S
G
S
V
K
Y
K
G
D
P
Q
-----------------------------------------------------------------------------
13
Fugue
25.39
16%
124
- C4 -
2KES
-
SNCAP_HUMAN
A:
[510-557]
------------------------
G
S
V
E
T
C
M
S
L
A
S
Q
V
V
K
L
T
K
Q
L
K
E
Q
T
V
E
R
V
T
L
Q
N
Q
L
Q
Q
F
L
E
A
Q
K
S
E
G
K
S
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
22.10
28%
141
- C4 -
2F3O
-
?
A:
[289-313]
-----------
D
I
G
-------
E
G
R
I
N
R
E
L
A
F
D
I
L
A
N
L
W
I
K
T
N
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
21.83
35%
150
- C4 -
2LSE
-
?
A:
[1-38]
-
M
Q
E
E
R
K
K
L
L
E
K
L
E
K
I
L
D
E
V
T
D
G
--
A
P
D
E
A
R
E
R
I
E
K
L
A
K
D
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
17.90
28%
157
* C4 *
4UOT
-
?
A:
[4-34]
T
Q
E
Y
L
L
K
E
I
M
K
L
L
K
-------
E
Q
I
K
L
L
K
E
Q
I
K
M
L
K
E
L
E
K
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
15.83
15%
181
- C4 -
1VP7
-
EX7S_BORPA
A:
[24-50]
--
L
A
E
L
E
S
L
V
S
A
M
E
-------
N
G
T
L
P
L
E
Q
S
L
S
A
Y
R
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------