@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : bsu00810: (2016-06-02 )
MFKIGDIQLKNRVVLAPMAGVCNSAFRLTVKEFGAGLVCAEMVSDKAILYNNARTMGMLYIDEREKPLSLQIFGGKKETLVEAAKFVDQNTTADIIDINMGCPVPKITKCDAGAKWLLDPDKIYEMVSAVVDAVNKPVTVKMRMGWDEDHIFAVKNAQAVERAGGKAVALHGRTRVQMYEGTANWDIIKEVKQSVSIPVIGNGDVKTPQDAKRMLDETGVDGVMIGRAALGNPWMIYRTVQYLETGKLKEEPQVREKMAVCKLHLDRLIDLKGENVAVREMRKHAAWYLKGVKGNANVRNEINHCETREEFVQLLDAFTVEVEAKELQNAKVG
Atome Classification :
(20 SA)
.........10......-..20-------........30.-------....-.-..40------.......-----------.50..--------..-.----.-..--60....---------.....70....----------------------------------------..------------..80.-.....-..90........100--------........110.......120.......130..--.....140.-....--.-----.150.........160.......170.......180--.--..-....-------..190...-.-...200.----......210.......220.......230.......240.......250.......260.......270...----....280........290.......300-.......310.....-..320.......330.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MFKIG
D
I
Q
L
KN
R
V
V
L
A
P
-
M
A
G
V
-------
C
N
S
A
F
R
L
T
V
K
E
-------FGA
G
-
L
-
V
C
A
E
------
M
VSD
K
A
I
-----------
L
YNNA--------
R
T
-
M
----
G
-
M
L
--
Y
-
I
DER---------EK
P
L
S
L
Q
I
FGG----------------------------------------
K
K
------------
E
T
L
V
E
-
A
A
K
F
V-DQNTTA
D
I
I
D
INMG---------CPVPKITKCDAG
A
K
WLL
D
P
D
K
I
Y
E
M
V
S
A
V
V
D
AV--NK
P
V
T
V
K
M
R-MGWD--E-----D
H
--
I
F
A
VK
N
A
Q
A
V
E
RAGG
K
A
V
A
L
HG
R
T
R
V
Q
M
YE----G--TA-
N
W
D
I
-------
I
K
E
V
K
Q
SV-S-I
P
V
IGNG----DVK
T
P
Q
D
A
K
R
M
L
D
E
TGVD
G
V
M
IGRAALGN
P
W
M
I
Y
R
T
V
Q
Y
L
E
TGKLKE
E
P
Q
V
R
E
K
M
A
V
C
K
L
H
L
D
R
L
IDLKGE
N
----
V
A
V
R
E
M
-
R
K
H
A
A
W
Y
L
KGVKGNANVR
N
E
I
-
N
H
C
E
T
R
E
E
F
V
Q
L
L
D
A
-
F
T
V
E
V
E
A
K
E
LQNAKVG
87
HHSearch
94.13
36%
-92
- C1 -
1VHN
4
?
A:
[5-309]
----------
V
K
V
G
L
A
P
-
M
A
G
Y
-------
T
D
S
A
F
R
T
L
A
F
E
-------
W
G
A
D
-
F
-
A
F
S
E
------
M
V
S
A
K
G
F
-----------
L
M
N
S
Q
--------
K
T
-
E
----
E
-
L
L
----
P
Q
P
H
---------
E
R
N
V
A
V
Q
I
F
G
S
----------------------------------------
E
P
------------
N
E
L
S
E
-
A
A
R
I
L
-
S
--
E
K
Y
K
W
I
D
L
N
A
G
---------
C
P
V
R
K
V
V
K
E
G
A
G
G
A
L
L
K
D
L
R
H
F
R
Y
I
V
R
E
L
R
K
S
V
--
S
G
K
F
S
V
K
T
R
-
L
G
W
E
--
K
-----
N
----
E
V
E
E
I
Y
R
I
L
V
E
E
G
V
D
E
V
F
I
H
T
R
T
V
V
Q
S
F
T
----
G
--
R
A
-
E
W
K
A
-------
L
S
V
L
E
K
---
R
-
I
P
T
F
V
S
G
----
D
I
F
T
P
E
D
A
K
R
A
L
E
E
S
G
C
D
G
L
L
V
A
R
G
A
I
G
R
P
W
I
F
K
Q
I
K
D
F
L
R
S
G
K
Y
-
S
E
P
S
R
E
E
I
L
R
T
F
E
R
H
L
E
L
L
I
K
T
K
G
E
R
----
K
A
V
V
E
M
-
R
K
F
L
A
G
Y
T
K
D
L
K
G
A
R
R
F
R
E
K
V
-
M
K
I
E
E
V
Q
I
L
K
E
M
F
Y
N
-
F
I
K
E
V
E
----------
1
PsiBlast_PDB
93.13
35%
-91
- C1 -
1VHN
4
?
A:
[5-309]
----------
V
K
V
G
L
A
P
-
M
A
G
Y
-------
T
D
S
A
F
R
T
L
A
F
E
-------
W
G
A
D
-
F
-
A
F
S
E
------
M
V
S
A
K
G
F
-----------
L
M
N
S
Q
--------
K
T
-
E
----
E
-
L
L
----
P
Q
P
H
---------
E
R
N
V
A
V
Q
I
F
G
S
----------------------------------------
E
P
------------
N
E
L
S
E
-
A
A
R
I
L
-
S
E
K
Y
--
K
W
I
D
L
N
A
G
---------
C
P
V
R
K
V
V
K
E
G
A
G
G
A
L
L
K
D
L
R
H
F
R
Y
I
V
R
E
L
R
K
S
V
--
S
G
K
F
S
V
K
T
R
-
L
G
W
E
--
K
-----
N
E
--
V
E
E
I
Y
R
I
L
V
E
E
--
G
V
D
E
V
F
I
H
T
R
T
V
V
Q
S
F
T
----
G
--
R
A
-
E
W
K
A
-------
L
S
V
L
E
K
R
----
I
P
T
F
V
S
G
----
D
I
F
T
P
E
D
A
K
R
A
L
E
E
S
G
C
D
G
L
L
V
A
R
G
A
I
G
R
P
W
I
F
K
Q
I
K
D
F
L
R
S
G
K
Y
S
-
E
P
S
R
E
E
I
L
R
T
F
E
R
H
L
E
L
L
I
K
T
K
G
E
R
----
K
A
V
V
E
M
-
R
K
F
L
A
G
Y
T
K
D
L
K
G
A
R
R
F
R
E
K
V
-
M
K
I
E
E
V
Q
I
L
K
E
M
F
Y
N
-
F
I
K
E
V
E
----------
107
Fugue
86.19
33%
-92
- C1 -
1VHN
4
?
A:
[5-309]
----------
V
K
V
G
L
A
P
M
A
-
G
Y
-------
T
D
S
A
F
R
T
L
A
F
E
-------
W
G
A
D
-
F
-
A
F
S
E
M-----
V
S
A
K
G
F
L
M
----------
N
S
Q
K
T
--------
E
E
-
L
----
L
-
P
------
Q
P
H
---------
E
R
N
V
A
V
Q
I
F
G
S
----------------------------------------
E
P
------------
N
E
L
S
E
-
A
A
R
I
L
-
S
E
K
--
Y
K
W
I
D
L
N
A
G
---------
C
P
V
R
K
V
V
K
E
G
A
G
G
A
L
L
K
D
L
R
H
F
R
Y
I
V
R
E
L
R
K
S
V
--
S
G
K
F
S
V
K
T
R
-
L
G
W
E
--
K
-----
N
E
--
V
E
E
I
--
Y
R
I
L
V
E
E
G
V
D
E
V
F
I
H
T
R
T
V
V
Q
S
F
T
----
G
--
R
A
-
E
W
K
A
-------
L
S
V
L
E
K
R
----
I
P
T
F
V
S
G
----
D
I
F
T
P
E
D
A
K
R
A
L
E
E
S
G
C
D
G
L
L
V
A
R
G
A
I
G
R
P
W
I
F
K
Q
I
K
D
F
L
R
S
G
K
Y
S
E
-
P
S
R
E
E
I
L
R
T
F
E
R
H
L
E
L
L
I
K
T
K
G
E
R
----
K
A
V
V
-
E
M
R
K
F
L
A
G
Y
T
K
D
L
K
G
A
R
R
F
R
E
K
V
M
K
-----
I
E
E
V
Q
I
L
K
E
M
F
Y
N
F
I
K
E
V
E
-------
89
HHSearch
81.43
26%
-100
- C1 -
3B0P
1
DUSAL_THET8
A:
[2-318]
--------
L
D
P
R
L
S
V
A
P
-
M
V
D
R
-------
T
D
R
H
F
R
F
L
V
R
Q
-------
V
S
L
G
-
V
R
L
Y
T
E
------
M
T
V
D
Q
A
V
-----------
L
R
G
N
R
--------
E
-------
R
-
L
L
--
A
-
F
R
P
E
---------
E
H
P
I
A
L
Q
L
A
G
S
----------------------------------------
D
P
------------
K
S
L
A
E
-
A
A
R
I
G
E
A
--
F
G
Y
D
E
I
N
L
N
L
G
---------
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
V
R
E
I
L
K
A
M
G
E
A
V
--
R
V
P
V
T
V
K
M
R
-
L
G
L
E
--
G
-----
K
E
T
Y
R
G
L
A
Q
S
V
E
A
M
A
E
A
G
V
K
V
F
V
V
H
A
R
S
A
L
---------IP
P
L
-
R
H
D
W
-------
V
H
R
L
K
G
D
F
P
Q
-
L
T
F
V
T
N
G
----
G
I
R
S
L
E
E
A
L
F
H
L
-
K
-
R
V
D
G
V
M
L
G
R
A
V
Y
E
D
P
F
V
L
E
E
A
D
R
R
V
F
G
L
P
--
R
R
P
S
R
L
E
V
A
R
R
M
R
A
Y
L
E
E
E
V
L
K
G
-------
T
P
P
W
A
V
-
L
R
H
M
L
N
L
F
R
G
R
P
K
G
R
L
W
R
R
L
L
-
S
E
G
R
S
L
Q
A
L
D
R
A
L
R
L
-
M
E
E
E
V
G
E
---------
108
Fugue
79.87
27%
-82
- C1 -
4BFA
6
DUSC_ECOLI
A:
[22-338]
--------
A
S
M
R
V
L
L
A
P
-
M
E
G
V
-------
L
D
S
L
V
R
E
L
L
T
E
V
N
DYD
L
C
I
T
E
F
-
V
-
R
V
V
D
------
Q
L
L
P
V
K
V
-----------
F
H
R
I
C
--------
P
E
-
L
----
Q
-
N
A
--
S
-
R
T
P
S
---------
G
T
L
V
R
V
Q
L
L
G
Q
----------------------------------------
F
P
------------
Q
W
L
A
E
N
A
A
R
A
V
-
E
L
G
S
W
G
--
V
D
L
N
C
G
---------
C
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
PA
H
L
P
V
S
V
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V
R
-
L
G
W
D
--
S
-----
G
E
---
K
K
F
E
I
A
D
A
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
----
A
--
E
H
I
D
W
Q
A
-------
I
G
D
I
R
Q
R
L
-
N
-
I
P
V
I
A
N
G
----
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
-
N
L
S
R
V
V
K
Y
N
E
P
---------
R
M
P
W
P
E
V
V
A
L
L
Q
K
Y
T
R
L
E
K
Q
G
DTGL
Y
H
V
A
R
I
-
K
Q
W
L
S
Y
L
R
K
E
Y
D
E
A
T
E
L
F
Q
H
V
-
R
V
L
N
N
S
P
D
I
A
R
A
I
Q
A
-
I
D
I
E
K
L
----------
3
PsiBlast_PDB
78.71
34%
-111
- C1 -
4BFA
5
DUSC_ECOLI
A:
[25-264]
-----------
R
V
L
L
A
P
-
M
E
G
V
-------
L
D
S
L
V
R
E
L
L
T
E
-------
V
N
D
Y
-
D
-
L
C
I
T
EFV---
R
V
V
D
Q
L
L
P
V
K
V
F
H
R
I
C
PE
L
Q
N
A
S
--------
R
T
P
S
----
G
-
T
L
--------------------
V
R
V
Q
L
L
G
Q
----------------------------------------
F
P
------------
Q
W
L
A
E
N
A
A
R
A
V
-
E
L
G
S
W
G
--
V
D
L
N
C
G
---------
C
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
PA
H
L
P
V
S
V
K
V
R
-
L
G
W
D
--
S
G----
E
K
--
K
F
E
I
--
A
D
A
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
----
A
--
E
H
I
D
W
Q
A
-------
I
G
D
I
R
Q
R
L
-
N
-
I
P
V
I
A
N
G
----
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
-
N
L
S
R
V
V
K
Y
N
E
------------------------------------------------------------------------------------------------
109
Fugue
77.26
26%
-89
- C1 -
3B0P
1
DUSAL_THET8
A:
[2-318]
--------
L
D
P
R
L
S
V
A
P
-
M
V
D
R
-------
T
D
R
H
F
R
F
L
V
R
Q
-------
V
S
L
G
V
R
-
L
Y
T
E
------
M
T
V
D
Q
A
V
-----------
L
R
G
N
----------
R
-
E
----
R
-
L
L
--
A
-
F
R
P
E
---------
E
H
P
I
A
L
Q
L
A
G
S
----------------------------------------
D
P
------------
K
S
L
A
E
-
A
A
R
I
G
-
E
A
F
G
Y
-
D
E
I
N
L
N
L
G
---------
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
V
R
E
I
L
K
A
M
G
E
A
V
--
R
V
P
V
T
V
K
M
R
-
L
G
L
E
GK
E
-----
T
Y
--
R
G
L
A
Q
S
V
E
A
M
A
E
A
G
V
K
V
F
V
V
H
A
R
S
---
A
L
I
----
P
--
P
L
-
R
H
D
W
-------
V
H
R
L
K
G
D
F
P
Q
-
L
T
F
V
T
N
G
----
G
I
R
S
L
E
E
A
L
F
H
L
K
R
--
V
D
G
V
M
L
G
R
A
V
Y
E
D
P
F
V
L
E
E
A
D
R
R
V
-----
F
G
L
P
R
R
P
S
R
L
E
V
A
R
R
M
R
A
Y
L
E
E
E
V
L
K
G
----
T
P
P
W
A
V
-
L
R
H
M
L
N
L
F
R
G
R
P
K
G
R
L
W
R
R
L
L
-
S
E
G
R
S
L
Q
A
L
D
R
A
L
R
L
-
M
E
E
E
V
G
E
---------
22
PsiBlast_CBE
77.00
33%
-108
- C1 -
4YCO
1
DUSC_ECOLI
C:
[8-247]
-----------
R
V
L
L
A
P
-
M
E
G
V
-------
L
D
S
L
V
R
E
L
L
T
E
-------
V
N
D
Y
-
D
-
L
C
I
T
EFV---
R
V
V
D
Q
L
L
PVKVFHRICPE
L
Q
N
A
S
--------
R
T
P
S
----
G
-
T
L
--------------------
V
R
V
Q
L
L
G
Q
----------------------------------------
F
P
------------
Q
W
L
A
E
N
A
A
R
A
V
-
E
L
G
S
W
G
--
V
D
L
N
C
G
---------
A
P
S
----
G
S
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
PA
H
L
P
V
S
V
K
V
R
-
L
G
W
D
--
S
G----
E
K
--
K
F
E
I
--
A
D
A
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
----
A
--
E
H
I
D
W
Q
A
-------
I
G
D
I
R
Q
R
L
-
N
-
I
P
V
I
A
N
G
----
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
-
N
L
S
R
V
V
K
Y
N
E
------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
76.18
34%
-112
- C1 -
4BFA
6
DUSC_ECOLI
B:
[25-264]
-----------
R
V
L
L
A
P
-
M
E
G
V
-------
L
D
S
L
V
R
E
L
L
T
E
-------
V
N
D
Y
-
D
-
L
C
I
T
EFV---
R
V
V
D
Q
L
L
P
V
K
V
F
H
R
I
CPE
L
Q
N
A
S
--------
R
T
P
S
----
G
-
T
L
--------------------
V
R
V
Q
L
L
G
Q
----------------------------------------
F
P
------------
Q
W
L
A
E
N
A
A
R
A
V
-
E
L
G
S
W
G
--
V
D
L
N
C
-------------------
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
PA
H
L
P
V
S
V
K
V
R
-
L
G
W
D
--
S
G----
E
K
--
K
F
E
I
--
A
D
A
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
----
A
--
E
H
I
D
W
Q
A
-------
I
G
D
I
R
Q
R
L
-
N
-
I
P
V
I
A
N
G
----
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
-
N
L
S
R
V
V
K
Y
N
E
------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
76.18
34%
-111
- C1 -
3W9Z
1
DUSC_ECOLI
A:
[2-252]
-----------
R
V
L
L
A
P
-
M
E
G
V
-------
L
D
S
L
V
R
E
L
L
T
E
-------
V
N
D
Y
-
D
-
L
C
I
T
EFV---
R
V
V
D
Q
L
L
P
V
K
V
F
H
R
I
C
PE
L
Q
N
A
S
--------
R
T
P
S
----
G
-
T
L
--------------------
V
R
V
Q
L
L
G
Q
----------------------------------------
F
P
------------
Q
W
L
A
E
N
A
A
R
A
V
-
E
L
G
S
W
G
--
V
D
L
N
C
G
---------
C
-------------
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
PA
H
L
P
V
S
V
K
V
R
-
L
G
W
D
--
S
G----
E
K
--
K
F
E
I
--
A
D
A
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
----
A
--
E
H
I
D
W
Q
A
-------
I
G
D
I
R
Q
R
L
-
N
-
I
P
V
I
A
N
G
----
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
-
N
L
S
R
V
V
K
Y
N
E
------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
75.96
33%
-106
- C1 -
4BF9
1
DUSC_ECOLI
A:
[25-264]
-----------
R
V
L
L
A
P
-
M
E
G
V
-------
L
D
S
L
V
R
E
L
L
T
E
-------
V
N
D
Y
-
D
-
L
C
I
T
EFV---
R
V
V
D
Q
L
L
P
V
K
V
F
H
R
I
C
PE
L
Q
N
A
S
--------
R
T
P
S
----
G
-
T
L
--------------------
V
R
V
Q
L
L
G
Q
----------------------------------------
F
P
------------
Q
W
L
A
E
N
A
A
R
A
V
-
E
L
G
S
W
G
--
V
D
L
N
C
G
---------
C
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
PA
H
L
P
V
S
V
K
V
R
-
L
G
W
D
--
S
G----
E
K
--
K
F
E
I
--
A
D
A
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
----
A
--
E
H
I
D
W
Q
A
-------
I
G
D
I
R
Q
R
L
-
N
-
I
P
V
I
A
N
G
----
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
-
N
L
S
R
V
V
K
Y
N
E
------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
75.58
33%
-108
- C1 -
4YCO
1
DUSC_ECOLI
A:
[8-247]
-----------
R
V
L
L
A
P
-
M
E
G
V
-------
L
D
S
L
V
R
E
L
L
T
E
-------
V
N
D
Y
-
D
-
L
C
I
T
EFV---
R
V
V
D
Q
L
L
P
V
K
V
F
H
R
I
C
PE
L
Q
N
A
S
--------
R
T
P
S
----
G
-
T
L
--------------------
V
R
V
Q
L
L
G
Q
----------------------------------------
F
P
------------
Q
W
L
A
E
N
A
A
R
A
V
-
E
L
G
S
W
G
--
V
D
L
N
C
G
---------
A
P
S
----
G
S
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
PA
H
L
P
V
S
V
K
V
R
-
L
G
W
D
--
S
G----
E
K
--
K
F
E
I
--
A
D
A
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
----
A
--
E
H
I
D
W
Q
A
-------
I
G
D
I
R
Q
R
L
-
N
-
I
P
V
I
A
N
G
----
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
-
N
L
S
R
V
V
K
Y
N
E
------------------------------------------------------------------------------------------------
88
HHSearch
75.51
26%
-79
- C1 -
4BFA
6
DUSC_ECOLI
A:
[22-334]
--------
A
S
M
R
V
L
L
A
P
-
M
E
G
V
-------
L
D
S
L
V
R
E
L
L
T
E
V
------
N
D
Y
D
-
L
-
C
I
T
E
------
F
V
R
V
V
D
Q
-----------
L
L
P
V
K
--------
V
F
-
H
R
I
C
P
E
-
L
Q
NA
S
-
R
T
P
S
---------
G
T
L
V
R
V
Q
L
L
G
Q
----------------------------------------
F
P
------------
Q
W
L
A
E
-
N
A
A
R
A
V
E
--
L
G
S
W
G
V
D
L
N
C
G
---------
C
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
PA
H
L
P
V
S
V
K
V
R
-
L
G
W
D
--
S
-----
G
E
---
K
K
F
E
I
A
D
A
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
----
A
E-
H
I
-
D
W
Q
A
-------
I
G
D
I
R
Q
R
L
-
N
-
I
P
V
I
A
N
G
----
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
N
L
S
R
V
V
K
Y
N
E
-
P
-----
R
M
P
W
P
E
V
V
A
L
L
Q
K
Y
T
R
L
E
K
Q
G
D
T
G
L
----
Y
H
V
A
R
I
-
K
Q
W
L
S
Y
L
R
K
E
Y
D
E
A
T
E
L
F
Q
H
V
-
R
V
L
N
N
S
P
D
I
A
R
A
I
Q
A
-
I
D
--------------
6
PsiBlast_PDB
75.48
33%
-102
- C1 -
4YCP
1
DUSC_ECOLI
A:
[8-247]
-----------
R
V
L
L
A
P
-
M
E
G
V
-------
L
D
S
L
V
R
E
L
L
T
E
-------
V
N
D
Y
-
D
-
L
C
I
T
EFV---
R
V
V
D
Q
L
L
P
V
K
V
F
H
R
I
C
PE
L
Q
N
A
S
--------
R
T
P
S
----
G
-
T
L
--------------------
V
R
V
Q
L
L
G
Q
----------------------------------------
F
P
------------
Q
W
L
A
E
N
A
A
R
A
V
-
E
L
G
S
W
G
--
V
D
L
N
C
G
---------
A
P
-------
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
PA
H
L
P
V
S
V
K
V
R
-
L
G
W
D
--
S
G----
E
K
--
K
F
E
I
--
A
D
A
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
----
A
--
E
H
I
D
W
Q
A
-------
I
G
D
I
R
Q
R
L
-
N
-
I
P
V
I
A
N
G
----
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
-
N
L
S
R
V
V
K
Y
N
E
------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
75.26
33%
-107
* C1 *
4YCO
1
DUSC_ECOLI
B:
[8-247]
-----------
R
V
L
L
A
P
-
M
E
G
V
-------
L
D
S
L
V
R
E
L
L
T
E
-------
V
N
D
Y
-
D
-
L
C
I
T
EFV---
R
V
V
D
Q
L
L
PVKVFHRICPE
L
Q
N
A
S
--------
R
T
P
S
----
G
-
T
L
--------------------
V
R
V
Q
L
L
G
Q
----------------------------------------
F
P
------------
Q
W
L
A
E
N
A
A
R
A
V
-
E
L
G
S
W
G
--
V
D
L
N
C
G
---------
A
P
S
----
G
S
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
PA
H
L
P
V
S
V
K
V
R
-
L
G
W
D
--
S
G----
E
K
--
K
F
E
I
--
A
D
A
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
E
Q
G
Y
R
----
A
--
E
H
I
D
W
Q
A
-------
I
G
D
I
R
Q
R
L
-
N
-
I
P
V
I
A
N
G
----
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
I
P
-
N
L
S
R
V
V
K
Y
N
E
------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
68.66
30%
-96
- C1 -
3B0P
1
DUSAL_THET8
A:
[2-235]
--------
L
D
P
R
L
S
V
A
P
-
M
V
D
R
-------
T
D
R
H
F
R
F
L
V
R
Q
-------
V
S
L
G
-
V
R
L
Y
T
E
------
M
T
V
D
Q
A
V
-----------
L
R
G
N
R
--------
E
R
-
L
-------
L
--
A
-
F
R
P
E
---------
E
H
P
I
A
L
Q
L
A
G
S
----------------------------------------
D
P
------------
K
S
L
A
E
-
A
A
R
-
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
---------
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
V
R
E
I
L
K
A
M
G
E
A
V
--
R
V
P
V
T
V
K
M
R
-
L
G
L
E
GK
E
-----
T
Y
--
R
G
L
A
Q
S
V
E
A
M
A
E
A
G
V
K
V
F
V
V
H
A
R
S
A
L
-----------------
I
PPLR
H
D
W
V
H
R
L
K
G
D
F
P
Q
-
L
T
F
V
T
N
G
----
G
I
R
S
L
E
E
A
--
L
F
H
L
K
R
V
D
G
V
M
L
G
R
A
V
Y
E
D
P
F
V
L
--------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
68.27
30%
-87
- C1 -
3B0U
3
DUSAL_THET8
X:
[2-235]
--------
L
D
P
R
L
S
V
A
P
-
M
V
D
R
-------
T
D
R
H
F
R
F
L
V
R
Q
-------
V
S
L
G
-
V
R
L
Y
T
E
------
M
T
V
D
Q
A
V
-----------
L
R
G
N
R
--------
E
R
-
L
-------
L
--
A
-
F
R
P
E
---------
E
H
P
I
A
L
Q
L
A
G
S
----------------------------------------
D
P
------------
K
S
L
A
E
-
A
A
R
-
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
---------
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
V
R
E
I
L
K
A
M
G
E
A
V
--
R
V
P
V
T
V
K
M
R
-
L
G
L
E
GK
E
-----
T
Y
--
R
G
L
A
Q
S
V
E
A
M
A
E
A
G
V
K
V
F
V
V
H
A
R
S
A
L
L
A
L
S
----
T
--
K
A
-
N
R
E
I
PPLRHDW
V
H
R
L
K
G
D
F
P
Q
-
L
T
F
V
T
N
G
----
G
I
R
S
L
E
E
A
--
L
F
H
L
K
R
V
D
G
V
M
L
G
R
A
V
Y
E
D
P
F
V
L
--------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
67.67
28%
-89
- C1 -
3B0V
1
DUSAL_THET8
C:
[22-256]
-------
M
L
D
P
R
L
S
V
A
P
-
M
V
D
R
-------
T
D
R
H
F
R
F
L
V
R
Q
-------
V
S
L
G
-
V
R
L
Y
T
E
------
M
T
V
D
Q
A
V
-----------
L
R
G
N
R
--------
E
R
-
L
-------
L
--
A
-
F
R
P
E
---------
E
H
P
I
A
L
Q
L
A
G
S
----------------------------------------
D
P
------------
K
S
L
A
E
-
A
A
R
-
I
-
G
E
A
F
G
Y
D
E
I
N
L
N
L
G
---------
C
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
V
R
E
I
L
K
A
M
G
E
A
V
--
R
V
P
V
T
V
K
M
R
-
L
G
L
E
GK
E
-----
T
Y
--
R
G
L
A
Q
S
V
E
A
M
A
E
A
G
V
K
V
F
V
V
H
A
R
S
A
L
L
A
L
S
----
T
--
K
A
-
N
R
E
I
PPLRHDW
V
H
R
L
K
G
D
F
-
P
Q
L
T
F
V
T
N
G
----
G
I
R
S
L
E
E
A
--
L
F
H
L
K
R
V
D
G
V
M
L
G
R
A
V
Y
E
D
P
F
V
L
--------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
67.60
30%
-97
- C1 -
4WFS
4
DUS2L_HUMAN
A:
[8-248]
------------
L
I
L
A
P
-
M
V
R
V
-------
G
T
L
P
M
R
L
L
A
L
D
-------
Y
G
A
D
-
I
-
V
Y
C
E
ELI
D
L
K
M
I
Q
C
K
R
V
-----------
V
N
E
V
L
--------
S
T
-
V
----
D
-
F
V
--
A
-
P
D
D
R
VV
F
R
T
C
ERE
Q
N
R
V
V
F
Q
M
G
T
S
----------------------------------------
D
A
------------
E
R
A
L
A
-
V
A
R
L
V
-
E
N
D
V
A
G
--
I
D
V
N
M
G
----------------------
A
L
L
S
D
P
D
K
I
E
K
I
L
S
T
L
V
K
G
T
--
R
R
P
V
T
C
K
I
R
I
L
P
S
L
--
E
-----
D
T
--
L
S
L
V
K
R
---
I
E
R
T
G
I
A
A
I
A
V
H
G
R
K
R
E
E
R
P
Q
----
H
--
P
V
-
S
C
E
V
-------
I
K
A
I
A
D
T
L
-
S
-
I
P
V
I
A
N
G
GSHD
H
I
Q
Q
Y
S
D
I
E
D
F
R
Q
A
T
A
A
S
S
V
M
V
A
R
A
A
M
W
N
P
S
I
F
L
K
------------------------------------------------------------------------------------------------------
96
HHSearch
63.02
19%
-69
- C1 -
3L5L
11
?
A:
[9-344]
--
T
L
K
D
V
T
L
R
N
R
I
A
I
P
P
-
M
C
Q
Y
MAEDGMI
N
D
W
H
H
V
H
L
A
G
L
A
R
-----
G
G
A
G
-
L
-
L
V
V
E
------
A
T
A
V
A
P
E
-----------
G
R
I
T
P
GCAGIWS
D
A
H
-
A
Q
A
F
-
V
P
V
V
--
Q
A
I
K
A
A
---------
G
S
V
P
G
I
Q
I
A
H
A
GRKASANRPWEGDDHIAADDTR
G
W
E
T
I
A
PSAIAFGAHLP
K
V
P
R
EMT
L
D
D
I
A
R
V
K
Q
D
F
V
D
-
A
A
R
R
A
R
D
--
A
G
F
E
W
I
E
L
H
F
A
HGY
L
G
Q
S
F
F
S
E
H
S
N
K
R
T
D
A
Y
G
G
S
F
D
N
R
S
R
F
L
L
E
T
L
A
A
V
R
E
V
W
PE
N
L
P
L
T
A
R
F
G
-
V
L
E
Y
--
D
GR
D
E
Q
T
L
--
E
E
S
I
E
L
A
R
R
F
K
A
G
G
L
D
L
L
S
V
S
V
G
F
T
I
P
D
T
N
IPWG
P
--
A
F
-
M
G
P
I
-------
A
E
R
V
R
R
E
A
-
K
-
L
P
V
T
S
A
W
----
G
F
G
T
P
Q
L
A
E
A
A
L
Q
A
N
Q
L
D
L
V
S
V
G
R
A
H
L
A
D
P
H
W
A
Y
F
A
A
K
E
L
G
V
-----------------------------------------------------------------------------------------------