@TOME V2.3
(Nov 2016)

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Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : ACKR4_HUMAN: (2016-01-08 )
MALEQNQSTDYYYEENEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTIVFVIGLAGNSMVVAIYAYYKKQRTKTDVYILNLAVADLLLLFTLPFWAVNAVHGWVLGKIMCKITSALYTLNFVSGMQFLACISIDRYVAVTKVPSQSGVGKPCWIICFCVWMAAILLSIPQLVFYTVNDNARCIPIFPRYLGTSMKALIQMLEICIGFVVPFLIMGVCYFITARTLMKMPNIKISRPLKVLLTVVIVFIVTQLPYNIVKFCRAIDIIYSLITSCNMSKRMDIAIQVTESIALFHSCLNPILYVFMGASFKNYVMKVAKKYGSWRRQRQSVEEFPFDSEGPTEPTSTFSI

Atome Classification :

(20 SA) .........10..----......20........30........40........50-------.........60........70........80........90..--..---....100--..--.--.....110.......120.......130.......140--.--------.-......150---...--..-....160.--........170..----.-..-----.---.180---..---..---.-----.-..--.190-......---...-----200.....---..210.......220------.....--.---------------------------------.230----------------.------------------------------------------------------------------------------------------------------------------------------------------------------------------.--------------------------------------------------------------------------------------------------------------------------------------------------------------------.--------------...-----------------------------------------------...240---.........250.......-------------260-..-......270---.........280.......---290.......300--------.......310.......--------320.......330.......340.......350------------------------------------------------------------------------------------------------------------
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MALEQNQSTDYYY----EENEMNGTYDYSQYELICIKEDVREFAKVFLPVFLTI--------VFVIGLAGNSMVVAIYAYYKKQRTKTDVYILNLAVADLLLLFT--LP---FWAVN-A--VH--G--WVLGKIMCKITSALYTLNFVSGMQFLACISIDRYVAV---T--------K-VPSQSGV-----GKP--CW-IICFC--V--WMAAILLSIPQLV----F-YT-----V---ND-----NA---RC---I-----P-IF--PR---YLGTSM---KAL-----IQMLEICI---GFVVPFLIMGVCYFI------TARTL--M---------------------------------KM------------------P------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------------------------I--------------KIS-----------------------------------------------RPLK-----VLLTVVIVFIVTQLPYNIV-------------KF--CR-AIDIIYS-----LITSCNMSKRMDIAIQVTE---SIALFHSCLNPIL--------YVFMGASFKNYVMKVAK--------KYGSWRRQRQSVEEFPFDSEGPTEPTSTFSI--------------------------------------------------------------------------------------------------------------
28 HHSearch 89.4233%-144 - C4 -3ODU CXCR4_HUMAN (first) A:[37-498] ---------------------------------PCFREENANFNKIFLPTIYSI--------IFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVIT--LP---FWAVD-A--VA--N--WYFGNFLCKAVHVIYTVNLYSSVWILAFISLDRYLAI---V--------H-ATNSQRPRK---LLA--EK-VVYVG--V--WIPALLLTIPDFI----F-AN-----V---SEAD---DR---YI---C-----D-RF-------YPNDLW---VVV-----FQFQHIMV---GLILPGIVILSCYCI------IISKL--S---------------------------------HS------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------SNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYGSKGH--------------QKR-----------------------------------------------KALK-----TTVILILAFFACWLPYYIG-------------IS--ID-SFILLEI-----IKQGCEFENTVHKWISITE---ALAFFHCCLNPIL--------YAFLGAKFKTSAQHALT--------SGRPLEVLFQ-----------------------------------------------------------------------------------------------------------------------------------
2 PsiBlast_PDB 84.6228%-149 - C4 -4MBS CCR5_HUMAN (first) A:[22-366] ----------------------------------CQKINVKQIAARLLPPLYSL--------VFIFGFVGNMLVILILINYKRLKSMTDIYLLNLAISDLFFLLT--VP---FWAHY-A--AA--Q--WDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAV---V--------H-AVFALKA-----RTV--TF-GVVTS--VITWVVAVFASLPNII----F-TR-----S---QK-----EGLHYTC---S-----S-HF--P----YSQYQF---WKN-----FQTLKIVIL--GLVLPLLVMVICYSG------ILKTL--L---------------------------------RMKKYTCTVCGYIYNPEDGDP------------------------------------------------------------------------------------------------------------------------------------------------------------------D--------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------------GVNPGTDFKDIPDDWVCPLCGVGKDQFEEVEEEKKRH-------------RDVR-----LIFTIMIVYFLFWAPYNIV-------------LL--LN-TFQEFFG-----L-NNCSSSNRLDQAMQVTE---TLGMTHCCINPII--------YAFVGEEFRNYLLVFFQ-----------------------------------------------------------------------------------------------------------------------------------------------------
47 Fugue 78.2928%-150 - C4 -4XNV P2RY1_HUMAN (first) A:[38-382] -------------------------------SFKC-ALTKTGFQFYYLPAVYIL--------VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLT--LP---ALIFY-Y--FN--KTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGV---V--------Y-PKSLGRL-----KKK--NA-ICISV--L--VWLIVVVAISPIL----F-YSGTGVRK---NK-----TI---TC---YDTTSDE-YL--RS---YFIYSM---CTT-----VAM---------FCVPLVLILGCYGL------IVRAL--IY--------------------------------KM------------------K------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------------------------------------------------Y--------------TCTVCGYIYNPEDGDPDNGVNPGTDFKDIVCPLCGVGKDQFEEVEEPLRRKSIY-----LVIIVLTVFAVSYIPFHVM-------------KT--MNLRARLDFQ-----TPAMCAFNDRVYATYQVTR---GLASLNSCVNPIL--------YFLAGDTFRRR-----------------------------------------------------------------------------------------------------------------------------------------------------------
8 PsiBlast_PDB 77.0928%-155 - C4 -4XT1 US28_HCMVA A:[23-318] --------------------------DYDEDATPCVFTDVLNQSKPVTLFLYGV--------VFLFGSIGNFLVIFTITWRRRIQCSGDVYFINLAAADLLFVCT--LP---LWMQY-L--LD---------SVPCTLLTACFYVAMFASLCFITEIALDRYYAI---V--------Y-MRYRP-V-----KQA--CL-FSIF---W--WIFAVIIAIPHFM----V-VT-----K---KD-----N----QC---M-----T-DY--D----YLEVSY---PII-----LNVELMLG---AFVIPLSVISYCYYR------ISRIV--A---------------------------------VS------------------Q------------------------------------------------------------------------------------------------------------------------------------------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------R--------------HKG-----------------------------------------------RIVR-----VLIAVVLVFIIFWLPYHLT-------------LF--VD-TLKLLKW-----ISSSCEFERSLKRALILTE---SLAFCHCCLNPLL--------YVFVGTKFRQELHCLLA--------EF----R--------------------------------------------------------------------------------------------------------------------------------------
52 Fugue 77.0227%-127 - C4 -3ODU CXCR4_HUMAN (first) A:[37-502] ---------------------------------PCFREENANFNKIFLPTIYSI--------IFLTGIVGNGLVILVMGYQKKLRSMTDKYRLHLSVADLLFVIT--LP---FWAVD-A--VA--N--WYFGNFLCKAVHVIYTVNLYSSVWILAFISLDRYLAI---VH-------A-TNSQRPR-----KLL--AEKVVYVG--V--WIPALLLTIPDFI----F-AN-----V---SE-----AD---DR---Y-----I-CD--RF---YPNDLW---VVV-----FQFQHIMV---GLILPGIVILSCYCI------IISKL--S---------------------------------H-------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------G--------------------------------------------------------------------------------------------------------------------------------------------------------------------S--------------NIF-----------------------------------------------EMLR-----IDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAA--KS-ELDKAIGRNTNGVITKDEAEKLFNQDVDAAV---RGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYGSKGHQKRKALKTTVILILAFFACWLPYYIGISIDSFILLEIIKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHALTSGRPLEVLFQ
16 PsiBlast_PDB 76.6527%-147 - C4 -4N6H OPRD_HUMAN A:[133-411] ----------------------------------------------------SA--------VCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATST--LP---FQSAKYL--ME--T--WPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAV---CHPVKALDFR-TPAKAK--------------LINIC--I--WVLASGVGVPIMV----M-AV-----TRP-RD-----GAV--VC---M-----L-QF--PSPSWYWDTVT---K------------ICVFLFAFVVPILIITVCYGL------MLLRL--RSVRLLSGS-------------------------KE------------------K------------------------------------------------------------------------------------------------------------------------------------------------------------------D--------------------------------------------------------------------------------------------------------------------------------------------------------------------R--------------SLR-----------------------------------------------RITR-----MVLVVVGAFVVCWAPIHIF-------------V---------IVWT-----LVDIDRRDPLVVAALHLCI---ALGYANSSLNPVL--------YAFLDENFKRCFRQLCR--------KPCG-----------------------------------------------------------------------------------------------------------------------------------------
49 Fugue 75.9317%-122 - C4 -1F88 OPSD_BOVIN A:[1-348] --MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYL------AEPWQFSMLAAYMFL--------LIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFG--GF---TTTLY-T--SLHGY--FVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVV---C--------KPMSNFRFG-----ENH--AI-MGVAF--T--WVMALACAAPPLVGWSRY-IP-----E---GM-----QC---SC---G-----IDYY--TP---HEETNN---ESF-----VIYMFVVH----FIIPLIVIFFCYGQ------LVFTV--K---------------------------------EA------------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------A--------------------------------------------------------------------------------------------------------------------------------------------------------------------S--------------ATT-----------------------------------------------QKAE-----KEVTRMVIIMVIAFLICWL-------------PY--AG-VAFYIFT-----HQGSDFGPIFMTIPAFFAK---TSAV----YNPVI--------YIMMNKQFRNCMVTTLC--------C------GKNPSTTVSKTETSQVAPA-------------------------------------------------------------------------------------------------------------------
9 PsiBlast_PDB 75.6828%-148 - C4 -4XT3 US28_HCMVA A:[26-316] -----------------------------EDATPCVFTDVLNQSKPVTLFLYGV--------VFLFGSIGNFLVIFTITWRRRIQCSGDVYFINLAAADLLFVCT--LP---LWMQY-L--LD--H-----ASVPCTLLTACFYVAMFASLCFITEIALDRYYAI---V--------Y-MRYRP-V-----KQA--CL-FSIF---W--WIFAVIIAIPHFM----V-VT-----K---KD-----N----QC---M-----T-DY--D----YLEVSY---PII-----LNVELMLG---AFVIPLSVISYCYYR------ISRIV--A---------------------------------VS------------------Q------------------------------------------------------------------------------------------------------------------------------------------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------R--------------HKG-----------------------------------------------RIVR-----VLIAVVLVFIIFWLPYHLT-------------LF--VD-TLKLLKW-----ISSSCEFERSLKRALILTE---SLAFCHCCLNPLL--------YVFVGTKFRQELHCLLA--------E--------------------------------------------------------------------------------------------------------------------------------------------
29 HHSearch 75.4720%-152 - C4 -3UON ACM2_HUMAN (first) A:[22-457] -------------------------------------------EVVFIVLVAGS--------LSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFS-MN---LYTLY-TV-IG--Y--WPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCV---T--------K-PLTYPVKRT---TKM--AG-MMIAA--A--WVLSFILWAPAIL----F-WQ-----F---IVGVRTVED---GE---C-----Y-IQ-------FF---S---NAA-----VTFGTAIA---AFYLPVIIMTVLYWH------ISRAS--K---------------------------------SR------------------INIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIGRNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAVNLAKSRWYNQTPNRAKRVITTFRTGTWDAYPPP--------------------------------------------------------------------------------------------------------------------------------------------------------------------S--------------REK-----------------------------------------------KVTR-----TILAILLAFIITWAPYNVM-------------VL--IN-TFCAPCI---------------PNTVWTIGY---WLCYINSTINPAC--------YALCNATFKKTFKHLLM-----------------------------------------------------------------------------------------------------------------------------------------------------
18 PsiBlast_PDB 75.1027%-149 - C4 -4RWD C562_ECOLX (first) A:[130-406] ----------------------------------------------------SA--------VCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATST--LP---FQSAKYL--ME--T--WPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAV---CHPVKALDFR-TPAKAK--------------LINIC--I--WVLASGVGVPIMV----M-AV-----TRP-RD-----GAV--VC---M-----L-QF--PSPSWYWDTVT---K------------ICVFLFAFVVPILIITVCYGL------MLLRL--RSVRLLSGS-------------------------KE------------------K------------------------------------------------------------------------------------------------------------------------------------------------------------------D--------------------------------------------------------------------------------------------------------------------------------------------------------------------R--------------SLR-----------------------------------------------RITR-----MVLVVVGAFVVCWAPIHIF-------------V---------IVWT-----LVDIDRRDPLVVAALHLCI---ALGYANSSLNPVL--------YAFLDENFKRCFRQLC------------------------------------------------------------------------------------------------------------------------------------------------------
12 PsiBlast_PDB 74.8026%-144 - C4 -4EA3 C562_ECOLX (first) A:[121-401] ------------------------------------------------PLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLT--LP---FQGTD-I--LL--GF-WPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAI---C--------H-P------T----SSK--AQ-AVNVA--I--WALASVVGVPVAI----M-GS-----AQVEDE-----EI---ECLVEI-----P-TP--QD---YWGP---------------VFAICIFLFSFIVPVLVISVCYSL------MIRRL--R---------------------------------GV------------------R------------------------------------------------------------------------------------------------------------------------------------------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------L--------------SGS-----------------------------------------------REKD-----RNLRRITRLVLVV--VAVF-------------VG--CW-TPVQVFV-----LAQGLGVQPSSETAVAILRFCTALGYVNSCLNPIL--------YAFLDENFKACFR---------------------------------------------------------------------------------------------------------------------------------------------------------
34 HHSearch 72.5633%-119 - C4 -2LNL - CXCR1_HUMAN A:[37-322] ------------------------------------------LNKYVVIIAYAL--------VFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALT--LP---IWAAS-K--VN--G--WIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAI---V--------H-ATRTLTQK----RHL--VK-FVCLG--C--WGLSMNLSLPFFL----F-RQ-----A---YHPNN--SS---PV---C-----Y-EV--LG---NDTAKW---RMV-----LRILPHTF---GFIVPLFVMLFCYGF------TLRTL--F---------------------------------KA------------------H------------------------------------------------------------------------------------------------------------------------------------------------------------------M--------------------------------------------------------------------------------------------------------------------------------------------------------------------G--------------QKH-----------------------------------------------RAMR-----VIFAVVLIFLLCWLPYNLV-------------LL--AD-TLMRTQV-----IQESCERRNNIGRALDATE---ILGFLHSCLNPII--------YAFIGQNFRHGFLKILA--------MHG------------------------------------------------------------------------------------------------------------------------------------------
40 HHSearch 72.5120%-140 - C4 -3PBL DRD3_HUMAN (first) A:[41-472] -----------------------------------------------