@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : OR2B3_HUMAN: (2016-01-13 )
MNWENESSPKEFILLGFSDRAWLQMPLFVVLLISYTITIFGNVSIMMVCILDPKLHTPMYFFLTNLSILDLCYTTTTVPHMLVNIGCNKKTISYAGCVAHLIIFLALGATECLLLAVMSFDRYVAVCRPLHYVVIMNYWFCLRMAAFSWLIGFGNSVLQSSLTLNMPRCGHQEVDHFFCEVPALLKLSCADTKPIEAELFFFSVLILLIPVTLILISYGFIAQAVLKIRSAEGRQKAFGTCGSHMIVVSLFYGTAIYMYLQPPSSTSKDWGKMVSLFYGIITSMLNSLIYSLRNKDMKEAFKRLMPRIFFCKK
Atome Classification :
(20 SA)
.......--------------..10......-----------------..20........30........40........50........60........70-----.....--.-..80--.........90........-100....-----...110..-.....120.......130.......140...----....150.......160.......170.......180.......--190-----.........200.......210.......220-----------........230--------------------.--------.-----------.....240------.......250-------.-------........260.---..---.-.--..270-------.---......280.--......290.......300.......310.----------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNWENES--------------SP
K
E
F
I
L
L
GF-----------------SDR
A
W
L
Q
M
P
L
F
V
V
L
L
I
S
Y
T
I
T
I
FGN
V
S
I
M
M
V
C
I
LDPKLHT
P
M
Y
F
F
LTN
L
S
I
L
D
L
-----CYTTT--T-V
P
H
---
M
L
V
NIGCNKKT
I
S
Y
A
G
C
V
A
-
H
L
I
I
F
L
A
-----
L
G
A
T
E
C
L
L
-
L
A
V
M
SF
D
R
Y
V
A
V
CRP
L
H
Y
V
V
I
M
N
Y
W
F
C
L
R
M
A
----
A
F
S
W
L
I
G
F
G
N
S
V
L
Q
S
S
LTLNMPRCG
H
Q
E
V
D
H
F
F
CE
V
P
A
L
L
K
LSC--A-------DTKP
I
E
A
E
L
F
F
F
S
V
L
I
L
L
I
P
V
T
L
I
L
I
S
Y
G
F
I
------------
A
Q
A
V
L
K
I
RSAE--------------------G--------
R
-----------
Q
K
A
F
GTCG------S
H
M
I
V
V
S
L
---------F-------YG
T
A
I
Y
M
Y
L
QPP---SS---T-
S
--
K
D
W
G
K
-------
M
---
V
S
L
F
Y
G
I
I
T
S
--
M
L
N
S
L
I
Y
S
L
RN
K
D
M
K
E
A
F
K
R
L
M
P
R
I
FFCKK----------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
90.65
20%
-149
- C3 -
3PWH
1
?
A:
[18-303]
------------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
-----
L
V
G
V
L
--
A
-
I
P
F
---
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
S
I
F
S
-
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
----
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
Q
P
--------
G
C
G
E
G
Q
V
A
C
LF
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
-----------
A
A
A
R
R
Q
L
K
Q
M
E
--------------------
S
--------
Q
PLPGE
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
------
S
A
A
I
I
A
G
L
---------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
---
C
S
---
H
-
A
--
P
L
W
L
M
-------
Y
---
L
A
I
V
L
A
H
T
N
S
--
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
90.29
20%
-143
- C3 -
3VGA
1
AA2AR_HUMAN
A:
[18-303]
------------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
-----
A
V
G
V
L
--
A
-
I
P
F
---
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
Q
S
S
I
F
S
-
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
----
A
I
C
W
V
L
S
F
A
I
G
L
---
T
P
M
L
G
W
N
N
C
G
Q
-------
S
Q
G
C
G
E
G
Q
V
A
C
L
F
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
R
R
Q
L
K
Q
M
E
S
Q
P
L
P
G
E
R
A
R
S
--------------------
T
--------
L
-----------
Q
K
E
V
H
A
A
K
------
S
L
A
I
I
V
G
L
---------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
---
C
S
---
H
-
A
--
P
L
W
L
M
-------
Y
---
L
A
I
V
L
S
H
T
N
S
--
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
H
V
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
89.99
20%
-149
- C3 -
3UZA
1
AA2AR_HUMAN
A:
[18-303]
------------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
-----
L
V
G
V
L
--
A
-
I
P
F
---
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
S
I
F
S
-
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
----
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
Q
P
--------
G
C
G
E
G
Q
V
A
C
L
F
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
-----------
A
A
A
R
R
Q
L
K
Q
M
E
--------------------
S
--------
Q
PLPG
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
------
S
A
A
I
I
A
G
L
---------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
---
C
S
---
H
-
A
--
P
L
W
L
M
-------
Y
---
L
A
I
V
L
A
H
T
N
S
--
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
89.80
20%
-147
- C3 -
3REY
1
AA2AR_HUMAN
A:
[18-303]
------------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
-----
L
V
G
V
L
--
A
-
I
P
F
---
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
S
I
F
S
-
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
----
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
Q
P
--------
G
C
G
E
G
Q
V
A
C
L
F
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
-----------
A
A
A
R
R
Q
L
K
Q
M
E
--------------------
S
--------
Q
PLPGE
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
------
S
A
A
I
I
A
G
L
---------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
---
C
S
---
H
-
A
--
P
L
W
L
M
-------
Y
---
L
A
I
V
L
A
H
T
N
S
--
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
89.31
20%
-148
- C3 -
3UZC
1
AA2AR_HUMAN
A:
[18-303]
------------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
-----
L
V
G
V
L
--
A
-
I
P
F
---
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
S
I
F
S
-
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
----
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
Q
P
--------
G
C
G
E
G
Q
V
A
C
L
F
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
-----------
A
A
A
R
R
Q
L
K
Q
M
E
--------------------
S
--------
Q
PLPG
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
------
S
A
A
I
I
A
G
L
---------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
---
C
S
---
H
-
A
--
P
L
W
L
M
-------
Y
---
L
A
I
V
L
A
H
T
N
S
--
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
88.85
20%
-126
- C3 -
1F88
8
OPSD_BOVIN
A:
[1-348]
M
N
G
T
E
G
P
NFYVPFSNKTGVVR
S
P
F
E
A
P
Q
Y
Y
L
-----------------
A
E
-
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
-----
F
M
V
F
G
--
G
-
F
T
T
---
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
-
E
G
F
F
A
T
L
-----
G
G
E
I
A
L
W
S
-
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
-
F
G
E
N
H
A
I
M
G
V
----
A
F
T
W
V
M
A
L
A
C
A
--------
A
P
P
L
V
G
W
S
R
------
Y
I
P
E
G
M
Q
C
S
C
--
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
------------
V
F
T
V
K
E
A
A
A
S
A
--------------------
T
--------
T
-----------
Q
K
A
E
K
E
V
T
------
R
M
V
I
I
M
V
I
---------
A
-------
F
L
I
C
W
L
P
Y
A
G
V
A
---
F
Y
---
I
-
F
--
T
H
Q
G
S
DFGPIFM
T
---
I
P
A
F
F
A
K
T
S
A
--
V
Y
N
P
V
I
Y
I
M
M
N
----
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
NPSTTVSKTETS
Q
V
A
P
A-----------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
88.47
20%
-146
- C3 -
3RFM
1
AA2AR_HUMAN
A:
[18-303]
------------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
-----
L
V
G
V
L
--
A
-
I
P
F
---
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
S
I
F
S
-
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
----
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
Q
P
--------
G
C
G
E
G
Q
V
A
C
L
F
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
-----------
A
A
A
R
R
Q
L
K
Q
M
E
--------------------
S
--------
Q
PLPG
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
------
S
A
A
I
I
A
G
L
---------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
---
C
S
---
H
-
A
--
P
L
W
L
M
-------
Y
---
L
A
I
V
L
A
H
T
N
S
--
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
87.59
20%
-145
- C3 -
3VG9
8
?
A:
[18-303]
------------------------------------------------------------------
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
-----
A
V
G
V
L
--
A
-
I
P
F
---
A
I
--------
T
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
CFV
L
V
L
T
Q
S
S
I
F
S
-
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
----
A
I
C
W
V
L
S
F
A
I
G
L
---
T
P
M
L
G
W
N
N
C
G
Q
-------
S
Q
G
C
G
E
G
Q
V
A
C
L
F
E
-------
D
V
V
P
M
N
Y
M
V
Y
F
N
F
F
A
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
R
R
Q
L
K
Q
M
E
S
Q
P
L
P
G
E
R
A
R
S
--------------------
T
--------
L
-----------
Q
K
E
V
H
A
A
K
------
S
L
A
I
I
V
G
L
---------
F
A
L
C
W
L
P
L
H
I
I
N
C
F
T
F
F
C
P
D
---
C
S
---
H
-
A
--
P
L
W
L
M
-------
Y
---
L
A
I
V
L
S
H
T
N
S
--
V
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
H
V
L
R
------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
87.45
17%
-140
- C3 -
2Z73
5
OPSD_TODPA
A:
[33-333]
-----------------------------------------------------
V
Y
Y
S
L
G
I
F
I
G
I
C
G
I
I
G
C
G
G
N
G
I
V
I
Y
L
F
T
K
T
K
S
L
Q
T
P
A
N
M
F
I
I
N
L
A
F
S
D
F
-----
T
F
S
L
V
--
N
G
F
P
L
---
M
T
I
S
C
F
L
K
K
W
I
F
G
F
A
A
C
K
V
-
Y
G
F
I
G
G
I
-----
F
G
F
M
S
I
M
T
-
M
A
M
I
S
I
D
R
Y
N
V
I
G
R
P
M
A
A
S
K
K
M
S
H
R
R
A
F
I
M
I
----
I
F
V
W
L
W
S
V
L
W
A
I
G
P
I
F
G
W
G
A
Y
T
----
L
E
G
V
L
C
N
C
S
F
D
Y
I
S
--------------
R
D
S
T
T
R
S
N
I
L
C
M
F
I
L
G
F
F
G
P
I
L
I
I
F
F
C
Y
F
N
I
------------
V
M
S
V
S
N
H
E
K
E
M
A
A
M
A
K
RLNAKE
L
R
K
A
Q
A
G
A
N
A
--------
E
-----------
M
R
L
A
K
I
S
I
------
V
I
V
S
Q
F
L
L
---------
S
-------
W
S
P
Y
A
V
V
A
L
L
A
Q
---
F
G
PLE
W
-
V
--
T
P
Y
A
A
-------
Q
---
L
P
V
M
F
A
K
A
S
A
--
I
H
N
P
M
I
Y
S
V
S
H
P
K
F
R
E
A
I
S
Q
T
F
P
W
V
L
T
C
C
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
85.97
21%
-121
- C3 -
1U19
15
OPSD_BOVIN
A:
[4-349]
M
N
--
G
T
E
--------------
G
P
N
F
Y
V
P
F
S
N
KTGVVRSPFEAPQYYLA
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
--
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
-----
F
M
V
F
G
--
G
-
F
T
T
---
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
-
E
G
F
F
A
T
L
-----
G
G
E
I
A
L
W
S
-
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
-
F
G
E
N
H
A
I
M
G
V
----
A
F
T
W
V
M
A
L
A
C
A
A
--------
P
P
L
V
G
W
S
R
Y
------
I
P
E
G
M
Q
C
S
C
--
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
------------
V
F
T
V
K
E
A
A
A
Q
Q
--------------------
Q
ESA
T
----
T
-----------
Q
K
A
E
K
E
V
T
------
R
M
V
I
I
M
V
I
---------
A
-------
F
L
I
C
W
L
P
Y
A
G
V
A
---
F
Y
---
I
-
F
--
T
H
Q
G
S
DFGPIFM
T
---
I
P
A
F
F
A
K
T
S
A
--
V
Y
N
P
V
I
Y
I
M
----
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
NPLGDDEA
S
T
T
V
S
K
TETSQVAPA-----------------------------------------------------------------------------------------------------------------------------------
48
Fugue
82.10
16%
-129
- C3 -
2RH1
16
ADRB2_HUMAN (first)
A:
[36-477]
--------------------------------------------------
D
E
V
W
V
V
G
M
G
I
V
M
S
L
I
V
L
A
I
V
F
G
N
V
L
V
I
T
A
I
A
K
F
E
R
L
Q
T
V
T
N
Y
F
I
T
S
L
A
C
A
D
L
-----
V
M
G
L
A
--
V
-
V
P
F
---
G
A
A
H
I
L
M
K
M
W
T
F
G
N
F
W
C
E
F
-
W
T
S
I
D
V
L
-----
C
V
T
A
S
I
E
T
-
L
C
V
I
A
V
D
R
Y
F
A
I
T
S
P
F
K
Y
Q
S
L
L
T
K
N
K
A
R
V
I
I
----
L
M
V
W
I
V
S
G
--
L
T
S
F
L
P
I
Q
M
H
W
Y
R
A
T
H
Q
E
A
I
N
C
Y
A
E
-----
E
T
C
C
--
D
-------
F
F
T
N
-
Q
A
Y
A
I
A
S
S
I
V
S
F
Y
V
P
L
V
I
M
V
F
V
Y
S
R
V
------------
F
Q
E
A
K
R
Q
L
N
I
F
--------------------
E
--------
M
-----------
L
R
I
D
E
G
L
R
------
L
K
I
Y
K
D
T
E
---------
G
-------
Y
Y
T
I
G
I
G
H
L
L
T
K
---
S
P
---
S
-
L
--
N
A
A
K
S
-------
E
---
L
D
K
A
I
G
R
N
T
N
GV
I
T
K
D
E
A
E
K
L
F
N
Q
D
V
D
A
A
V
R
G
I
L
R
N
A
K
L
K
P
V
Y
D
S
LD
A
V
R
R
A
A
L
I
N
M
V
F
Q
MG
E
T
G
V
A
G
F
T
N
S
L
R
M
L
Q
Q
KR
W
D
E
A
A
V
N
L
A
K
S
R
W
Y
N
Q
T
P
N
R
A
K
R
V
I
T
T
F
R
TGTWDAYKFCL
K
E
H
K
A
L
K
T
L
G
I
I
M
G
T
F
T
L
C
W
L
P
F
F
I
V
N
I
V
H
V
I
QDNLIR
K
E
V
Y
I
L
L
N
W
I
G
Y
V
N
S
G
F
N
PLIYCRS
P
D
F
R
I
A
F
Q
E
L
L
CL
10
PsiBlast_PDB
81.59
21%
-136
- C3 -
3C9L
13
OPSD_BOVIN
A:
[44-315]
---------------------------------------------------------
M
F
L
L
I
M
L
G
F
P
I
----
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
Y
T
-
S
L
H
GYF
V
F
G
P
T
G
C
N
L
E
G
------------
F
F
A
T
-----
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
-----
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
--------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
--
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
---------------
Q
L
V
F
T
V
K
E
A
A
--------------------
A
--------
Q
-----------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
-------
A
G
V
A
F
Y
I
F
-------
T
H
---
Q
-
G
--
S
D
F
G
P
-------
I
FM
T
I
P
A
F
F
A
K
T
S
A
--
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
D
D
E
----------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
80.99
14%
-136
* C3 *
2KS9
1
NK1R_HUMAN
A:
[33-324]
-------------------------------------------------------
V
L
W
A
A
A
Y
T
V
I
V
V
T
S
V
V
G
N
V
V
V
M
W
I
I
L
A
H
K
R
M
R
T
V
T
N
Y
F
L
V
N
L
A
F
A
E
A
-----
S
M
A
A
F
--
N
-
T
V
V
---
N
F
T
Y
A
V
H
N
E
W
Y
Y
G
L
F
Y
C
K
F
-
H
N
F
F
P
I
A
-----
A
V
F
A
S
I
Y
S
-
M
T
A
V
A
F
D
R
Y
M
A
I
I
H
P
L
Q
P
R
L
--
S
A
T
A
T
K
V
V
I
----
C
V
I
W
V
L
A
L
L
L
A
F
P
Q
G
Y
Y
S
T
T
E
----
T
-
M
P
S
R
V
V
C
M
I
E
W
P
E
H
P
------------
N
K
I
Y
E
K
V
Y
H
I
C
V
T
V
L
I
Y
F
L
P
L
L
V
I
G
Y
A
Y
T
V
V
------------
G
I
T
L
W
A
S
E
I
P
G
DSSDRYH
E
Q
V
S
---------
A
--------
K
-----------
R
K
V
V
K
M
M
I
------
V
V
V
C
T
F
A
I
---------
C
-------
W
L
P
F
H
I
F
F
L
L
P
Y
I
NP
D
L
---
Y
L
K
KF
I
Q
Q
V
Y
-------
L
---
A
I
M
W
L
A
M
S
S
T
--
M
Y
N
P
I
I
Y
C
C
L
N
D
R
F
R
L
G
F
K
H
A
F
R
C
C
P
F
I
S
A
----------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
80.05
21%
-140
- C3 -
3DQB
4
GNAT1_BOVIN (first)
A:
[44-315]
---------------------------------------------------------
M
F
L
L
I
M
L
G
F
P
I
----
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
Y
T
-
S
L
H
GYF
V
F
G
P
T
G
C
N
L
E
G
------------
F
F
A
T
-----
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
-----
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
--------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
--
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
---------------
Q
L
V
F
T
V
K
E
A
A
--------------------
A
--------
Q
-----------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
-------
A
G
V
A
F
Y
I
F
-------
T
H
---
Q
-
G
--
S
D
F
G
P
-------
I
F
M
T
I
P
A
F
F
A
K
T
S
A
--
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
79.77
21%
-143
- C3 -
1F88
7
OPSD_BOVIN
A:
[44-315]
---------------------------------------------------------
M
F
L
L
I
M
L
G
F
P
I
----
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
Y
T
-
S
L
H
GYF
V
F
G
P
T
G
C
N
L
E
G
------------
F
F
A
T
-----
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
-----
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
--------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
--
G
I
DYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
---------------
Q
L
V
F
T
V
K
E
A
A
--------------------
A
-----------------------
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
-------
A
G
V
A
F
Y
I
F
-------
T
H
---
Q
-
G
--
S
D
F
G
P
-------
I
FM
T
I
P
A
F
F
A
K
T
S
A
--
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
P
S
T
----------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
79.42
16%
-131
- C3 -
1U19
14
OPSD_BOVIN
A:
[40-327]
------------------------------------------------------
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
-----
F
M
V
F
G
--
G
-
F
T
T
---
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
-
E
G
F
F
A
T
L
-----
G
G
E
I
A
L
W
S
-
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
-
G
E
N
H
A
I
M
G
V
----
A
F
T
W
V
M
A
L
A
C
A
A
P
P
L
V
G
W
S
R
Y
---
I
P
-
E
G
M
Q
C
S
C
G
I
D
Y
Y
T
P
-----
H
-------
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
------------
V
F
T
V
K
E
A
A
A
Q
Q
--------------------
Q
ESA
T
T
Q
K
A
E
-----------
K
E
V
T
R
M
V
I
------
I
M
V
I
A
F
L
I
---------
C
-------
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
-
Q
G
S--
D
-
F
--
G
P
I
F
M
-------
T
---
I
P
A
F
F
A
K
T
S
A
--
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
P
L
G
----------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
79.30
21%
-142
- C3 -
3PQR
9
OPSD_BOVIN
A:
[44-315]
---------------------------------------------------------
M
F
L
L
I
M
L
G
F
P
I
----
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
FG
G
F
T
T
T
L
Y
T
-
S
L
H
GYF
V
F
G
P
T
G
C
N
L
E
G
------------
F
F
A
T
-----
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
-----
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
--------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
--
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
---------------
Q
L
V
F
T
V
K
E
A
A
--------------------
A
--------
Q
-----------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
-------
A
G
V
A
F
Y
I
F
-------
T
H
---
Q
-
G
--
S
D
F
G
P
-------
I
F
M
T
I
P
A
F
F
A
K
T
S
A
--
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
79.08
21%
-143
- C3 -
3PXO
4
OPSD_BOVIN
A:
[44-315]
---------------------------------------------------------
M
F
L
L
I
M
L
G
F
P
I
----
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
Y
T
-
S
L
H
GYF
V
F
G
P
T
G
C
N
L
E
G
------------
F
F
A
T
-----
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
-----
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
--------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
--
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
---------------
Q
L
V
F
T
V
K
E
A
A
--------------------
A
--------
Q
-----------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
-------
A
G
V
A
F
Y
I
F
-------
T
H
---
Q
-
G
--
S
D
F
G
P
-------
I
F
M
T
I
P
A
F
F
A
K
T
S
A
--
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
78.96
21%
-139
- C3 -
3CAP
4
OPSD_BOVIN
A:
[44-315]
---------------------------------------------------------
M
F
L
L
I
M
L
G
F
P
I
----
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
Y
T
-
S
L
H
GYF
V
F
G
P
T
G
C
N
L
E
G
------------
F
F
A
T
-----
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
-----
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
--------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
--
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
---------------
Q
L
V
F
T
V
K
E
A
A
--------------------
A
--------
Q
-----------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
-------
A
G
V
A
F
Y
I
F
-------
T
H
---
Q
-
G
--
S
D
F
G
P
-------
I
F
M
T
I
P
A
F
F
A
K
T
S
A
--
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
78.74
21%
-140
- C3 -
4J4Q
8
GNAT1_BOVIN (first)
A:
[44-315]
---------------------------------------------------------
M
F
L
L
I
M
L
G
F
P
I
----
N
F
L
T
L
Y
V
T
V
Q
H
K
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
F
T
T
T
L
Y
T
-
S
L
H
GYF
V
F
G
P
T
G
C
N
L
E
G
------------
F
F
A
T
-----
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
-----
N
F
R
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
--------------
C
A
A
P
P
L
V
G
W
S
R
Y
I
P
E
G
M
Q
C
S
C
--
G
IDYYTPH
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
---------------
Q
L
V
F
T
V
K
E
A
A
--------------------
A
--------
Q
-----------
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
-------
A
G
V
A
F
Y
I
F
-------
T
H
---
Q
-
G
--
S
D
F
G
P
-------
I
F
M
T
I
P
A
F
F
A
K
T
S
A
--
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------