@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0121: (2015-11-28 )
MKLSIYVTLSISLVLILLQVTVTFKDWDSYKEYIVQGLEKTYNAKVHIGGKVEVSLITPKLTVHNVYMQCNNNKEQKLSTLIGVNKIEVRPSILSLFLFSLQPKSITLLGMKSNRENFINIINAKTSSNAVDIVIKGSQVSLNNNFTDYDNIVNIEKVAIGKSKQFSGEIRVDSNDYDFSGKVNITKKNVHISVESNFINLLFTGKKNQAGLQGKLTLTINNSSDFINDLAKITNLSFLAYVIPGENIEISSNIDFNGNDFTATDLKIKSKSMQASGIIQNDRKSNHTNINISFSKVNLDSIRNSSRRIIDIKDLLECFRKVVPRNLSLDFNIEASNIQYQNKILDKSHAILKFADGEIKVDMLLKFPGTNNVSHLSGKVSNSGTLSEFNGNLLVKGDNFKSFISCFFPSIKIKGNQKNQFTLSSELHFAPRILSISNIRFLNDKEFLQGSIKVSHTKKHNVVGGRFSVHNLDADKYDYSLFSSLSKMGWLKNLRYDVSIKINANDFKLNDTKIKDLDFLLKMEKGKLVVDKINLSGEDCDINGSTKILVDQRYTKPLLEVNLTGNKFNGDIFKLPSFIEVKRDSRNKINQIQWSTKQFDFLDNKESFDANVQINAIEFRVGQNVLKDFNLDAVVRNNTVTMRQVSYALEHGQVFFQGYLRSDSMYTKFLITNLDAKGIGKAIGIDNVDGRISLNGEIKAQGKSFHGWANNLSGEINLQAQEIEFTNVDFNSFITNLLNGKNKSEISTLAHDDIYNGSTLFENVIGKANIKNGVCSTSLQFRIDQASGSISSNLTLPNFALISLVRFFFILPGHSSPIYIDMHLDGPIWHPKMNFDVDQIFSTLKRIRSIKFIFAK
Atome Classification :
(20 SA)
-------.........10----........20--.........30........40.....-...50........60........70.----.......-80........90........100.......110.......120.-......130.-----......140.....-.--.150-.......160.......170.......180....-----------------...190..----...-..200--....-....210.---......220..--...-----..230.......240.......250.---..--....260----------.-......270-----........280.......290....---....300.--......310.....-..320..-......-330.......340.......350......-.-360-.........370----.......380....---...390....----...400....--...410--------------.........420---.......----430.......440...-....450...-....460.......470-...--....480.......490.......500.......510.--......520........530----...-.....540...----....550.---..-----....560.......570.......580.......590...-....600.......610.......620.......630------......----...640.......650....----..----.660.......670.....---..680.......690..---------------.....700.......710.......720..------.....730.-----......740.-------------------......750.......760--.......770.......780.......-790.......800.......810.......820.....-----..830.......840.......850....----------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------
M
K
L
S
I
Y
V
T
L
S
I
----
S
L
V
L
I
L
L
Q
V
---
T
V
T
FK
D
W
D
S
Y
K
E
Y
I
V
Q
G
L
E
K
TYN
A
K
V
-
H
IG
G
K
V
E
V
S
L
ITP
K
L
T
V
H
N
V
Y
M
Q
CNN----
N
K
E
Q
K
L
S
-
T
L
IG
V
N
K
I
E
V
R
P
S
I
L
S
L
F
L
F
SLQPK
S
I
T
L
L
GMKSNRE
N
F
I
N
I
I
N-AKTSS
N
A
V
D
I
-----
V
I
KG
S
Q
V
S
LNNNFT-D--YDN
I
-
V
N
I
E
K
V
AIGKSKQFS
G
E
I
R
VDSNDYDFSG
K
V
N
I
T
-----------------
K
K
N
V
H
I
S
V
----ES
N
-
F
I
N
L
---
L
F
TG-KKNQAGL
Q
---
G
K
L
T
L
T
INN
S
S
--
D
F
I
-----
N
D
L
A
K
ITN
L
S
F
L
A
Y
V
IPGE
N
I
E
I
SSN---ID--FNGND
F
T
----------
A
-
T
D
L
K
I
KSK------SMQAS
G
I
IQNDRKSNH
T
N
I
N
-
I
S
F
S
---
K
V
N
L
D
S
IR--NSS
R
R
I
I
D
I
K
D
L
L
E
-
C
F
R
-
K
VV-PRN
L
S
L
-
D
F
N
I
EASN
I
Q
Y
Q
N
K
ILDKS
H
A
I
L
K
FADG
E
-
I
-
K
---
V
D
M
L
L
KFPGTNN----
V
S
H
LSGKVSNSGTL---SEFNG
N
L
L
V
K----GD
N
F
K
S
F
I
S
C
--FFP
S
----------------
I
K
I
KGNQK
N
Q
F
T
---LSSELHF----A
P
R
I
L
S
I
S
N
I
R
FL
N
D
K
-
E
F
LQG
S
I
K
V
S-HTKKHNVVGG
R
F
S
V
HNL-DA
D
--
K
Y
D
Y
S
L
F
S
S
L
S
K
M
G
W
L
K
NL
R
Y
D
V
S
I
K
I
NAN
D
F
KLNDTK--I
K
D
L
D
F
L
-LKMEKG
K
L
V
V
D
-----
K
IN-LSGEDCDINGS----
T
K
I
L
V
DQR---YT-----K
P
L
L
E
V
NLTGNKFNGDIFKLPS
F
I
E
VKRDSRNKI
N
Q
I
Q
WS-TKQFDFLDNKESFDA
N
V
Q
I
N
A
I
E
F
R
V
G
Q
N
V
L
K
DFN--------L
D
A
V
V
R----NN
T
V
T
M
R
Q
V
S
Y
A
L
EH
G
Q
V
F
F
----
Q
G
----
Y
LRSDS
M
Y
T
K
F
L
I
TNLDAK---GIGKAIGIDNVD
G
R
I
S
L---------------N
G
E
I
K
AQGKSFHGWANNLS
G
E
I
N
L
Q
A
Q
E
I
E
------
F
TNV
D
F
N
S
F
-----
I
T
N
L
LNGK
N
K
-------------------
S
E
I
S
T
L
AHDDIYN
G
S
T
L
F
E
--
N
V
IGKANIKNGVCST
S
L
Q
F
R
I
DQASGS-ISSNLTL
P
N
F
A
L
I
S
L
V
R
F
F
F
ILPGHSS
P
I
Y
I
D
M
HLDGP-----IWHPKMNF
D
V
D
Q
I
F
S
T
L
K
R
I
R
S
I
K
F
I
FAK----------------------------
17
Fugue
94.57
15%
-26
- C8 -
4W8J
3
CR1AC_BACTK
A:
[33-1178]
YT
P
I
D
I
S
L
S
L
T
Q
F
L
L
S
E
F
VPG
A
G
F
V
L
G
L
V
D
I
IWG
I
F
G
P
S
Q
W
D
A
F
L
V
Q
I
E
Q
L
I
N
Q
R
I
E
E
F
A
-
R
N
Q
A
I
S
R
L
E
G
L
S
N
L
Y
Q
I
Y
A
E
S
F
R
E
W
E
A
DPT
N
P
A
L
R
E
E
-
M
R
I
Q
F
N
D
M
N
S
A
L
T
T
A
I
P
L
L
-
A
V
Q
N
Y
Q
V
P
L
L
S
V
Y
V
Q
A
A
N
L
H
L
S
V
L
-
R
D
V
S
V
F
G
Q
R
W
GFD
A
A
T
I
N
S
R
Y
N
D
L
T
R
L
I
G
-
N
--
Y
T
D
Y
-
A
-
V
R
W
Y
N
T
G
L
E
R
V
W
G
P
D
S
R
D
W
V
R
Y
N
Q
F
R
R
E
L
T
L
T
V
L
D
I
V
A
L
FPNYDSRRYP
I
R
T
V
S
Q
L
T
----
R
E
I
-
Y
T
N
P
---
V
L
E
N
F
D
G
S
F
R
G
S
A
---
Q
G
I
E
R
S
I
R
S
P
H
L
M
D
I
L
-----
N
S
I
T
I
Y
T
D
A
H
R
G
Y
Y
Y
W
S
G
H
Q
I
M
A
S
P
----
V
G
--
F
S
G
P
E
F
T
F
P
LYGTMGNA
A
-
P
Q
Q
R
I
V
A
Q
LGQGVY
R
T
L
S
S
T
L
Y
R
R
P
F
N
Q
Q
L
S
V
L
D
G
T
E
F
A
Y
G
T
S
S
N
L
P
S
A
V
--
Y
R
K
S
G
T
V
D
S
L
D
E
I
P
-
P
Q
N
-
N
N
V
-
P
P
R
Q
G
F
-
S
H
R
L
S
H
V
S
M
F
R
S
G
F
V
S
I
I
R
A
P
M
F
S
W
I
H
R
S
-
A
-
E
---
V
N
N
I
I
A
S
D
S
I
T
Q
----
I
P
A
V
K
G
N
F
L
F
N
G
S
V
I
S
G
P
G
F
T
G
G
D
L
V
R
L
N
S
S
N
I
Q
N
R
G
Y
I
E
V
P
I
H
F
P
S
TS
T
R
Y
R
V
R
V
R
Y
A
S
V
T
P
I
H
L
N
V
N
W
G
N
S
S
I
---
F
S
N
T
V
P
A
TATS
L
D
N
L
Q
S
S
D
F
G
Y
F
E
S
A
N
-
A
F
T
G
N
I
V
G
V
R
N
F
S
G
T
A
G
V
I
I
D
R
F
E
F
I
P
V
T
A
T
L
--
E
A
E
Y
N
L
E
R
A
Q
K
A
V
N
A
L
F
T
S
T
N
Q
L
G
L
K
T
N
V
T
D
Y
H
I
D
Q
V
S
N
L
V
T
Y
L
S
D
E
-
F
S
L
D
E
K
R
E
L
S
E
-----
K
V
K
-
H
A
K
R
L
S
D
E
R
-------
N
L
L
Q
D
S
N
---
F
K
-----
D
I
N
R
E
R
G
W
G
G
S
---------
T
G
I
T
I
Q
G
G
D
D
V
F
K
E
N
Y
V
T
L
S
-
G
------
T
F
D
E
S
Y
P
T
Y
L
Y
Q
K
I
D
E
S
K
L
K
A
F
T
R
Y
Q
L
R
---------
G
Y
I
E
D
----
S
Q
D
L
E
I
Y
L
I
R
Y
N
A
K
H
E
T
V
N
V
----
P
G
T
G
SS
A
H
H
S
H
H
F
S
L
D
I
D
V
G
S
T
D
L
N
EDL
G
V
W
V
I
F
K
I
K
T
Q
D
G
H
A
R
L
G
N
L
E
F
L
E
E
K
PLVG
E
A
L
A
R
V
K
R
A
E
K
K
W
R
D
K
R
E
K
L
E
W
E
T
N
I
V
Y
K
E
A
K
E
S
V
D
A
L
F
V
N
S
Q
Y
D
Q
L
QADTN
I
A
M
I
H
A
A
D
K
R
V
H
SIREAYLPELSVIPGVN
A
A
I
F
E
E
L
E
G
R
I
F
T
A
F
S
L
Y
D
A
R
N
V
I
K
N
G
D
F
N
N
G
L
S
S
W
N
V
K
G
H
V
D
V
E
E
Q
N
N
Q
R
S
V
L
V
V
P
E
W
E
-
A
E
V
S
Q
E
V
R
V
S
P
G
R
G
Y
I
L
R
V
T
A
Y
K
E
G
Y
G
E
G
S
V
T
I
H
E
I
E
N
N
T
D
E
L
K
F
S
N
P
V
G
Y
V
T
K
E
L
E
Y
F
P
ETD
K
V
W
I
E
I
G
E
TE
G
T
F
I
V
D
S
V
E
L
L
L
MEE
24
Fugue
86.25
15%
-32
- C4 -
4LXR
11
TOLL_DROME
A:
[1-773]
------S
F
G
R
D
A
C
S
E
M
S
I
----
D
---
G
L
C
Q
C
---
A
P
I
M
----
S
E
Y
E
I
I
C
P
A
N
A
E
N
P
T
F
R
L
-
T
I
Q
P
K
D
Y
V
Q
I
M
C
-
N
L
T
D
T
T
D
Y
Q
Q
L
P
K
----
K
-----
L
-
R
I
G
E
V
D
R
V
Q
M
R
R
C
M
L
P
------------------
G
H
T
P
I
A
S
I
L
D
-
Y
L
G
I
V
S
P
T
T
L
-----
I
F
E
S
D
N
L
G
M
N
I
T
R
Q
-
H
--
L
D
R
L
-
H
G
L
K
R
F
R
F
T
T
R
R
L
T
H
I
P
A
N
L
L
T
D
M
R
N
L
S
---------------------------
H
L
E
L
----
R
A
N
-
I
E
E
M
PSH
L
F
D
D
-
L
E
N
L
E
S
I
E
FGS
N
K
L
R
Q
M
P
R
G
I
F
--
G
K
M
-----
P
K
L
K
Q
L
N
L
W
S
N
Q
L
H
N
L
T
K
H
D
F
E
G
A
T
S
VLG
I
D
--
I
H
D
N
G
I
E
----------
Q
-
L
P
H
D
V
F
A
H
------
L
T
N
V
T
D
I
N
L
S
A
N
L
F
R
S
L
P
Q
G
-
L
F
D
H
---
N
K
H
L
N
E
V
R
LM
N
N
R
V
P
L
A
T
L
P
S
R
L
F
-
A
N
Q
-
P
E
L
--
Q
I
L
R
L
-
R
A
E
L
Q
----
S
L
P
G
D
L
F
E
H
S
T
Q
I
T
N
I
S
L
G
D
-
N
-
L
---
L
K
T
L
P
A
T
L
L
E
H
Q
----
V
N
L
L
S
L
D
L
S
N
N
-
R
L
---
T
H
L
P
D
S
L
F
A
H
----
T
T
N
L
T
----------
D
----------------
L
R
L
E
D
N
L
L
T
G
I
S
GDI
F
S
N
L
G
N
L
----
V
T
L
V
M
S
R
N
R
L
R
T
I
D
S
R
-
A
F
V
S
T
N
G
L
R
H
-
L
H
L
D
H
N
D
I
D
L
Q
Q
P
L
L
D
I
-
M
L
Q
--
T
Q
I
N
S
P
F
G
Y
M
H
G
L
L
T
L
-
N
L
R
N
N
-
S
I
I
F
V
Y
N
D
W
K
N
T
M
L
Q
--
L
R
E
L
D
-
L
-
S
Y
N
N
I
S
S
L
G
Y
E
-----
D
L
A
F
L
S
Q
N
R
L
H
V
N
M
T
HNKI
R
R
I
A
L
P
E
D
---
V
N
-----
N
N
L
V
H
V
D
L
N
D
N
P
L
V
C
D
-
C
T
I
L
W
F
I
Q
L
V
R
G
V
H
K
P
Q
Y
S
R
Q
F
K
-
L
R
T
D
R
L
V
C
S
Q
P
N
V
L
E
G
T
P
V
R
Q
I
E
---
P
Q
T
L
I
C
P
L
D
--------
F
S
K
C
P
R
----
G
C
N
C
H
V
R
T
-----------------------------
Y
D
K
A
L
V
I
N
C
H
S
G
---
N
L
T
H
V
P
R
L
P
N
L
H
K
N
M
Q
----------------
L
M
E
L
H
L
E
N
N
T
L
L
R
L
P
S
A
--------------------
N
T
P
G
Y
E
S
V
-----
T
S
L
H
L
A
G
N
N
L
-------------------
T
S
I
---------
D
V
D
Q
L
P
T
--
N
L
------------
T
H
L
D
I
S
W
N
H
L
Q
M
L
-
N
A
T
V
L
G
F
L
N
W
R
S
V
K
L
S
G
N
P
W
M
C
D
C
T
A
K
P
L
L
L
F
T
Q
D
N
F
E
-----
R
I
G
D
R
N
E
M
M
C
V
N
A
P
T
R
M
V
E
L
-
S
T
N
D
I
C
P
-----------------------------
16
Fugue
80.52
18%
-24
* C6 *
4AQ1
4
?
A:
[172-892]
-------
A
V
P
E
I
V
E
V
T
A
V
----
N
S
T
T
V
K
V
T
F
---
N
T
Q
I
A
D
V
D
-
F
T
N
F
A
I
D
N
G
L
T
V
T
K
A
T
L
S
R
D
K
K
S
V
E
V
V
V
N
K
P
----------
F
T
R
----
N
Q
E
Y
T
I
T
A
T
G
I
K
N
L
K
G
E
T
A
K
E
L
T
G
K
F
V
W
S
V
Q
D
A
V
T
V
A
L
N
N
S
S
L
K
V
G
E
E
S
G
L
T
-
V
K
D
Q
D
G
K
D
--------
V
V
G
A
K
V
E
L
T
S
S
------
N
T
N
I
-
V
V
V
S
S
G
E
V
S
V
S
A
--
A
K
V
T
A
V
K
P
G
T
A
D
V
T
A
K
V
T
L
P
-----------------
D
G
V
----
V
----
L
T
N
-
T
F
K
V
---
T
V
T
E
-
V
P
V
Q
V
Q
N
Q
---
G
-
F
T
L
V
-
D
N
L
S
--
N
A
P
-----
Q
N
T
V
A
F
N
K
A
E
K
V
T
S
M
F
A
G
E
T
K
T
V
A
M
----
Y
D
--
T
K
N
G
D
P
E
----------
T
-
K
P
V
D
F
K
D
A
------
T
V
R
S
L
N
P
I
I
A
T
A
A
I
N
G
S
E
L
L
-
V
T
A
N
---
A
------
G
--
Q
S
G
K
A
S
F
E
V
T
------
F
K
-
D
N
T
-
K
R
T
F
T
V
-
D
V
K
K
E
P
V
-------------------
L
Q
D
-
I
-
K
---
V
D
A
--------
T
----
S
V
K
L
S
D
E
A
V
G
G
G
E
V
---
E
G
V
N
-------------------------
Q
----------------
K
T
I
K
V
S
A
V
D
Q
Y
-----
G
K
E
I
K
F
----
G
T
K
------------------
G
K
V
T
V
T
-
T
N
T
E
G
L
V
I
K
N
V
N
S
D
N
T
I
-
D
F
D
SG
N
S
A
T
D
Q
F
V
V
V
A
T
K
D
K
I
V
N
G
K
V
E
V
K
Y
F
K
N
A
S
D
T
T
P
T
S
T
K
--
T
I
T
V
N
V
V
N
V
K
A
D
A
T
P
V
G
L
D
IVAPS
E
I
D
-
V
N
A
P
N
T
A
S
T
A
D
----
V
D
F
I
N
F
E
S
V
E
I
Y
T
L
D
SNG
N
R
L
K
K
V
T
P
T
A
T
T
L
V
G
T
----
N
D
Y
V
E
V
N
G
------
N
V
L
Q
F
K
G
N
D
E
L
T
L
L
T
S
S
S
T
V
N
V
D
V
T
A
D
G
I
T
K
R
I
P
V
K
Y
I
N
S
A
S
--------
V
P
A
S
A
T
V
A
T
S
P
V
T
V
K
L
N
S
S
D
N
D
L
T
F
E
E
L
I
F
G
V
I
D
P
T
----
Q
L
V
K
D
E
D
I
N
E
F
I
A
V
S
K
A
A
K
---
N
D
G
Y
L
Y
N
K
P
L
V
T
V
K
D
A
----------------
S
G
E
V
I
P
T
G
A
N
V
Y
G
---------------
L
N
------
H
D
A
T
N
G
N
I
W
-----
F
D
E
E
Q
A
G
L
A
K
-------------------
K
------
F
S
D
V
H
-------------------
F
D
V
D
F
S
L
A
N
V
V
K
T
G
S
G
T
-
V
S
S
S
P
S
L
S
D
---------
A
I
Q
L
T
N
S
G
D
A
V
S
F
T
L
V
I
K
S
------
I
Y
V
K
G
A
D
K
D
D
N
N
L
---
L
A
A
P
V
S
V
N
V
T
V
T
K
G
S--------------------------
5
PsiBlast_PDB
54.84
28%
43
- C10 -
2LKF
-
HLGB_STAAU
A:
[20-162]
-------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
A
T
A
D
S
D
-----
K
F
K
I
S
Q
I
L
T
F
N
F
I
K
-
D
KS
Y
D
K
D
-
T
L
V
L
K
-
A
T
G
N
I
N
--
S
G
F
V
K
P
N
P
N
D
Y
D
F
S
K
L
Y
W
G
A
-----------------
K
Y
N
V
S
I
S
S
----
Q
S
N
D
S
V
N
V
---
V
D
Y
A
-
P
K
N
Q
----------------------------
N
E
E
F
Q
V
Q
N
T
--
L
G
Y
T
F
G
G
D
-
I
S
I
S
N
G
---
L
---
L
N
G
N
T
A
F
----------
S
-
E
T
I
N
Y
K
Q
E
------
S
Y
R
T
T
----
L
S
R
N
T
N
Y
K
N
V
G
-
W
G
V
E
---
A
H
K
I
M
N
N
G
--
W
G
P
Y
G
R
D
S
F
H
P
T
Y
G
-
N
E
L
-
F
L
A
-
G
R
Q
S
S
A
-
Y
A
G
Q
N
F
I
A
Q
H
Q
M
P
L
L
S
R
S
N
F
N
P
E
F
L
S
V
L
S
-
H
-
R
---
Q
D
G
A
K
K
S
K
I
T
V
T
----
Y
Q
R
E
M
D
L
Y
Q
I
R
W
N
G
---
F
Y
W
A
G
A
N
Y
K
N
----
F
K
T
R
T
F
K
S
T
Y
--
E
I
D
W
----------------
E
N
H
K
V
K
L
L
D
T
K
E
---
T
E
N
N
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
52.45
18%
49
- C6 -
3Q87
1
?
A:
[1-125]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
----
K
P
F
L
L
G
L
L
K
C
K
R
C
S
F
M
-
T
K
L
I
--
L
E
C
E
-
K
A
E
S
N
D
V
D
V
K
I
F
N
K
H
M
F
-
T
E
N
--
G
G
E
R
L
K
S
L
V
N
S
L
R
D
F
H
G
R
E
L
S
E
Q
D
I
S
S
F
V
E
N
-
P
G
D
D
E
K
--
I
K
E
F
L
F
G
-
I
D
V
V
E
G
S
L
R
C
D
-----
M
----
C
G
L
I
Y
P
I
K
G
S
----
I
V
E
T
V
D
T
V
---
E
S
-----
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
50.60
17%
-5
- C8 -
3RMH
-
?
A:
[611-740]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
--
Y
E
V
V
E
D
H
N
I
S
Q
L
N
H
--
L
Q
-
H
L
T
-
P
K
I
Y
V
L
-
N
V
Y
I
I
D
V
E
I
V
Y
---------------
D
Q
E
-
I
-
R
---
I
K
V
V
N
E
L
P
L
V
G
K
Y
V
P
P
V
D
I
L
E
V
Y
I
T
G
K
E
E
V
---
Q
N
F
L
G
D
E
V
L
T
----
M
D
I
F
T
P
L
L
N
-----
E
T
----------------
S
R
L
R
V
F
Q
R
P
-------
D
R
I
I
R
W
----
S
P
I
E
C
T
I
Q
E
L
R
L
Q
R
M
F
-
R
L
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
50.34
28%
69
* C10 *
3B07
-
?
A:
[30-172]
-------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
A
T
A
D
S
D
-----
K
F
K
I
S
Q
I
L
T
F
N
F
I
K
-
D
KS
Y
D
K
D
-
T
L
V
L
K
-
A
T
G
N
I
N
--
S
G
F
V
K
P
N
P
N
D
Y
D
F
S
K
L
Y
W
G
A
-----------------
K
Y
N
V
S
I
S
S
----
Q
S
N
D
S
V
N
V
---
V
D
Y
A
-
P
K
N
Q
----------------------------
N
E
E
F
Q
V
Q
N
T
--
L
G
Y
T
F
G
G
D
-
I
S
I
S
N
G
---
L
S
G
G
L
N
G
N
T
A
F
----------
S
-
E
T
I
N
Y
K
Q
E
------
S
Y
R
T
T
----
L
S
R
N
T
N
Y
K
N
V
G
-
W
G
V
E
---
A
H
K
I
M
N
N
G
--
W
G
P
Y
G
R
D
S
F
H
P
T
Y
G
-
N
E
L
-
F
L
A
-
G
R
Q
S
S
A
-
Y
A
G
Q
N
F
I
A
Q
H
Q
M
P
L
L
S
R
S
N
F
N
P
E
F
L
S
V
L
S
-
H
-
R
---
Q
D
G
A
K
K
S
K
I
T
V
T
----
Y
Q
R
E
M
D
L
Y
Q
I
C
W
N
G
---
F
Y
W
A
G
A
N
Y
K
N
----
F
K
T
R
T
F
K
S
T
Y
--
E
I
D
W
----------------
E
N
H
K
V
K
L
L
D
T
K
E
---
T
E
N
N
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
44.90
35%
118
- C10 -
2QK7
-
HLGB_STAAU
B:
[20-104]
-------------------------------------------------------------------------------------------------------------------------------------------------
K
T
T
A
T
A
D
S
D
-----
K
F
K
I
S
Q
I
L
T
F
N
F
I
K
-
D
KS
Y
D
K
D
-
T
L
V
L
K
A
A
G
N
I
N
---
S
G
Y
E
K
P
N
P
N
D
Y
D
F
S
K
L
Y
W
G
A
-----------------
K
Y
N
V
S
I
S
S
----
Q
S
N
D
S
V
N
V
---
V
D
Y
A
-
P
K
N
Q
N
E
E
F
---
Q
V
Q
N
T
L
G
Y
T
F
G
--
G
D
I
-----
S
I
S
N
G
L
T
A
F
S
E
T
I
N
Y
K
Q
E
S
Y
R
T
T
L
S
R
---
C
T
--
N
Y
K
N
V
G
W
----------
G
-
V
E
A
H
K
I
M
N
------
N
G
W
G
P
Y
G
R
D
S
F
H
P
T
Y
G
N
E
L
F
-
L
A
G
R
---
A
Y
A
G
Q
N
F
I
--
A
Q
H
Q
M
P
L
L
S
R
S
N
F
N
-
P
E
F
-
L
S
V
-
L
S
H
R
Q
D
-
G
A
K
K
S
K
I
T
V
T
Y
Q
R
E
M
D
L
Y
Q
I
R
W
N
G
F
Y
W
A
G
-
A
-
N
---
Y
K
N
F
K
T
R
T
F
K
S
T
----
Y
E
I
D
W
E
N
H
K
V
K
L
L
D
---
T
K
E
T
E
N
N
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
44.68
16%
64
- C5 -
4H3W
-
?
A:
[38-350]
---------------------------------------------------------------------------------------------------------------------------------------
E
S
W
V
A
P
L
G
M
G
Y
V
T
S
D
D
V
V
N
-----
V
E
V
P
S
I
R
E
V
D
G
A
Y
V
M
I
--
Y
D
G
E
M
I
G
-
S
L
R
A
A
S
D
V
E
I
A
S
E
D
I
T
T
G
D
I
D
G
L
F
D
G
D
F
V
L
A
-----------------
L
T
N
P
H
I
T
L
SNVN
A
S
L
-
D
C
S
L
---
S
I
E
A
-
E
N
T
S
E
A
T
S
---
S
D
F
T
L
S
T
V
S
P
N
--
I
W
I
G
PLDP
T
D
A
F
F
V
N
E
L
P
G
I
V
Q
I
V
P
Q
I
H
L
S
L
S
A
D
---
S
Q
--
W
T
N
A
P
A
D
----------
A
L
S
E
L
R
Y
A
V
E
L
-----
P
L
T
P
A
P
E
F
S
A
V
S
V
E
R
I
E
D
----
A
F
D
---
E
D
F
V
D
Y
I
F
--
S
D
G
S
A
R
I
Y
G
E
V
T
N
E
M
P
F
D
M
S
I
E
M
V
----
I
M
D
E
N
N
V
P
V
D
I
Q
F
P
A
Q
E
V
G
Q
S
G
E
V
I
F
E
I
T
E
D
M
P
M
D
AR
H
I
D
L
N
L
H
L
T
G
R
D
Q
---------
G
E
A
L
G
Q
T
T
F
---
N
L
L
E
G
G
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
41.76
24%
74
- C7 -
1LC3
2
BIEA_RAT
A:
[117-183]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
L
H
E
E
H
V
E
L
L
M
E
E
F
E
F
L
R
R
E
V
L
G
K
-
E
L
L
K
G
S
L
---
R
F
T
A
S
P
L
-
E
E
E
--
R
F
G
F
P
A
F
S
G
I
S
R
L
T
W
L
V
S
L
F
G
E
L
S
L
I
S
A
T
L
E
E
R
K
E
D
Q
Y
--
M
K
M
T
V
Q
L
-
E
T
Q
N
K
G
L
L
S
W
I
-----
E
E
K
-
G
P
G
L
K
R
N
R
Y
V
N
----
F
Q
F
T
S
G
S
L
---
E
E
-----
V
P
S
V
G
V
N
K
N
I
F
L
K
D
Q
D
I
F
V
Q
K
L
L
D
Q
V
S
A
E
D
L
A
A
E
K
K
R
I
M
H
-
C
L
G
L
A
S
D
I
Q
K
L
C
H
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
41.75
24%
78
- C7 -
1LC0
-
BIEA_RAT
A:
[117-183]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
L
H
E
E
H
V
E
L
L
M
E
E
F
E
F
L
R
R
E
V
L
G
K
-
E
L
L
K
G
S
L
---
R
F
T
A
S
P
L
-
E
E
E
--
R
F
G
F
P
A
F
S
G
I
S
R
L
T
W
L
V
S
L
F
G
E
L
S
L
I
S
A
T
L
E
E
R
K
E
D
Q
Y
--
M
K
M
T
V
Q
L
-
E
T
Q
N
K
G
L
L
S
W
I
-----
E
E
K
-
G
P
G
L
K
R
N
R
Y
V
N
----
F
Q
F
T
S
G
S
L
---
E
E
-----
V
P
S
V
G
V
N
K
N
I
F
L
K
D
Q
D
I
F
V
Q
K
L
L
D
Q
V
S
A
E
D
L
A
A
E
K
K
R
I
M
H
-
C
L
G
L
A
S
D
I
Q
K
L
C
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
41.23
17%
68
* C8 *
1ZV1
-
DSX_DROME
A:
[6-64]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
D
V
F
L
D
Y
C
Q
K
L
L
E
K
F
R
YPWEL
M
P
L
M
Y
V
I
L
K
----
D
A
D
A
N
I
E
E
A
S
R
R
I
E
E
G
Q
Y
V
V
----
N
E
----
Y
S
R
Q
H
N
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
40.76
24%
68
- C7 -
1GCU
-
BIEA_RAT
A:
[118-184]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
L
H
E
E
H
V
E
L
L
M
E
E
F
E
F
L
R
R
E
V
L
G
K
-
E
L
L
K
G
S
L
---
R
F
T
A
S
P
L
-
E
E
E
--
R
F
G
F
P
A
F
S
G
I
S
R
L
T
W
L
V
S
L
F
G
E
L
S
L
I
S
A
T
L
E
E
R
K
E
D
Q
Y
--
M
K
M
T
V
Q
L
-
E
T
Q
N
K
G
L
L
S
W
I
-----
E
E
K
-
G
P
G
L
K
R
N
R
Y
V
N
----
F
Q
F
T
S
G
S
L
---
E
E
-----
V
P
S
V
G
V
N
K
N
I
F
L
K
D
Q
D
I
F
V
Q
K
L
L
D
Q
V
S
A
E
D
L
A
A
E
K
K
R
I
M
H
-
C
L
G
L
A
S
D
I
Q
K
L
C
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
27.33
18%
835
- C9 -
1VCP
-
POLS_SFV
A:
[21-37]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
M
K
P
A
H
V
K
G
V
-----
I
D
N
A
D
L
A
K
L
A
F
K
K
S
S
K
Y
D
L
E
C
A
Q
I
P
V
H
M
R
----------------------------
9
HHSearch
24.38
22%
906
- C9 -
1EP5
-
POLS_EEVV8
B:
[27-44]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
L
F
R
P
M
H
V
E
G
K
-----
I
D
N
D
V
L
A
A
L
K
T
K
K
A
S
K
Y
D
L
E
Y
A
D
V
P
Q
N
M
R
----------------------------
15
HHSearch
24.15
24%
749
* C7 *
2YEW
-
POLS_BFV
A:
[125-141]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
M
K
P
A
H
V
K
G
T
-----
I
D
N
P
E
L
---------------------------------------------------
8
HHSearch
22.02
47%
795
- C7 -
3WU2
-
PSBL_THEVL
L:
[15-29]
---------
T
S
L
Y
L
G
L
L
L
----
I
L
V
L
A
L
L
F
S
---
S
Y
F
F
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
21.71
33%
1117
* C9 *
1KXF
-
POLS_SINDV
A:
[137-151]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
P
L
H
V
K
G
T
-----
I
D
H
P
V
L
---------------------------------------------------
11
HHSearch
18.93
20%
1221
- C1 -
3KL4
-
DAP2_YEAST
B:
[17-27]
--------------
G
I
I
L
----
V
L
L
I
W
G
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
17.22
18%
665
- C7 -
2LK9
-
BST2_HUMAN
A:
[22-38]
---------
L
L
L
G
I
G
I
L
V
----
L
L
I
I
V
I
L
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------