@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Wbm0785: (2015-12-04 )
MSKKDYYKLLGVDRNASTDEIKKAYKKLALKYHPDRNPGNKEAEEKFKEITAAYEVLSDSEKRAGYDRYGHEGASGGFDFSQGFGSAGDFSDIFNDFFGGEFGSSSRSKAKRSTTGVPGADLRYDLEITLEDAFKGIQAPIHYVTNVKCDMCQGRGSEGATKPVQCHTCQGSGRIRTQQGFFTIERTCTTCYGEGEIIQNKCKKCNGSGRRRDEVNISVSIPKGIEEGAKVRVSGKGEAGAKGGKSGDLYVYVKITPHKIFTRNKADLHCKVPIRMTLAVLGGEIDVQSIDGAKIKVKVPEGTQTSTKLRCKEKGMPYMNSYARGDLYVQIIVETLNPNNLTKKQIELLKALEEEENASIQQQSEGFFSKVKKK
Atome Classification :
(20 SA)
.........10........20........30......--..40.-........50........60........70...-----.....80........90........-100.......110.......120.......130.......140.......150....-..-.160.......170.----------------......--180......---...190-......--.--200.......210........220.......230.......240........250....-...260.......270.......280.......290.......300--.......310.........320........330.......340.......350.......360.......370..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSKK
D
Y
Y
K
L
LGVDRNA
S
T
D
E
I
K
K
A
Y
K
K
L
A
L
K
YHPDRN--PG
N
-
K
-
E
A
E
E
K
F
K
E
I
T
A
A
Y
E
V
LSD
S
E
KRAGYDRYGHEGA-----SGGF
D
F
S
QGFGSAG
D
F
S
D
I
F
N
D
F
FG-GEFGSSSRSKAKRSTTGVPGA
D
L
R
Y
D
L
E
I
T
L
E
D
A
F
K
G
I
Q
A
P
I
H
Y
V
TNV
K
C
DMCQGRG-SE-GATK
P
V
Q
C
H
TCQGS
G
----------------
R
I
R
TQQ--
G
--
F
F
T
I
E
R
---
T
C
TTCY-GE
G
E
I
I
--
Q
--
N
K
C
K
KCNGSGR-RR
D
E
V
N
I
S
V
SIPKGIEEG
A
K
V
R
V
SGKGEAG-AKGGKSG
D
L
Y
V
Y
V
K
IT-
P
H
K
I
F
TRNKA
D
L
H
C
KV
P
I
R
M
T
L
A
V
LGGE
I
D
V
Q
SIDG
A
K
I
K
V
KVPEG--TQTS
T
K
L
R
--CKEKGMP
Y
M
N
S-YARG
D
L
Y
V
Q
I
I
V
ETLNPNNL
T
K
K
Q
I
E
L
L
K
A
L
E
E
EENA
S
I
Q
Q
Q
S
E
G
F
F
S
K
VKKK
1
PsiBlast_PDB
82.82
35%
-66
- C2 -
4J80
-
DNAJ2_THET8
A:
[3-260]
-
A
K
K
D
Y
Y
A
I
L
G
V
P
R
N
A
T
Q
E
E
I
K
R
A
Y
K
R
L
A
R
Q
Y
H
P
D
V
N
---
K
S
-
P
-
E
A
E
E
K
F
K
E
I
N
E
A
Y
A
V
M
S
D
P
E
K
R
R
I
Y
D
T
Y
G
T
T
E
A
PPPPP
P
G
G
Y
D
F
S
-
G
F
-
D
V
E
D
F
S
E
F
F
Q
E
L
F
G
P
G
L
F
G
K
--------------
G
R
D
L
R
A
E
L
P
L
T
L
E
E
A
F
H
G
G
E
R
V
V
E
-
V
A
G
R
R
V
S
V
R
M
P
P
G
V
R
E
-
G
S
V
I
R
V
P
G
M
G
G
Q
G
N
P
P
G
D
L
L
L
V
V
R
M
L
PHP
V
F
R
L
E
G
Q
D
--
L
--
Y
A
T
L
D
V
---
P
A
P
I
A
------
V
V
--
G
--
G
K
V
R
A
M
T
L
E
G
-------
P
V
E
V
A
V
P
P
R
T
Q
A
G
R
K
M
R
L
K
G
G
G
F
P
G
-
P
A
G
--
R
G
D
L
Y
L
E
V
R
I
T
I
P
E
R
L
T
P
E
E
E
A
L
W
K
K
L
A
E
A
Y
Y
A
R
-----------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
73.78
30%
-75
- C1 -
1NLT
3
MAS5_YEAST
A:
[8-235]
-----------------------------------------------------------------------------------------------------------------------------
P
Q
R
G
K
D
I
K
H
E
I
S
A
S
L
E
E
L
Y
K
G
R
T
A
K
L
A
L
N
K
Q
I
L
C
K
E
C
E
G
R
G
-
G
K
K
G
A
V
K
--
K
C
T
S
C
N
G
Q
G
I
---------------
K
F
V
T
R
Q
--
M
--
G
P
M
I
Q
R
F
Q
T
E
C
D
V
C
H
-
G
T
G
D
I
I
D
P
K
--
D
R
C
K
S
C
N
G
K
K
V
-
E
N
E
R
K
I
L
E
V
H
V
E
P
G
M
K
D
G
Q
--
R
I
V
F
K
G
E
A
D
Q
A
P
D
V
I
P
G
D
V
V
F
I
V
S
E
R
-
P
H
K
S
F
K
R
D
G
D
D
L
V
Y
E
A
E
I
D
L
L
T
A
I
A
G
G
E
F
A
L
E
H
V
S
G
D
W
L
K
V
G
I
V
P
G
--
E
V
I
A
P
G
M
R
K
V
I
E
G
K
G
M
P
I
P
K
Y
-
G
G
Y
G
N
L
I
I
K
F
T
I
K
--
D
P
E
-----------------------------------
47
HHSearch
73.24
33%
-100
- C1 -
3LZ8
-
?
A:
[113-294]
-----------------------------------------------------------------------------------------------------------------------------
A
A
R
G
H
D
L
E
I
E
V
A
V
F
L
E
E
T
L
A
E
Q
T
R
T
I
S
Y
N
L
P
V
Y
N
--
V
F
-------------------
G
-----------------------------------------------------------------
I
E
-
S
E
T
P
K
T
L
N
V
K
I
P
A
G
V
V
D
G
Q
R
I
R
L
K
G
Q
G
T
P
G
----
G
P
N
G
D
L
W
L
V
I
H
I
A
-
P
H
P
L
F
D
I
V
G
H
N
L
E
I
V
L
P
L
A
P
W
E
A
A
L
G
A
K
V
T
V
P
T
L
K
E
-
S
I
L
L
T
V
P
P
G
--
S
Q
A
G
Q
R
L
R
--
I
K
G
K
G
L
V
S
K
T
---
H
T
G
D
L
F
A
V
I
K
I
V
M
--
P
T
K
P
D
E
K
A
R
E
L
W
Q
Q
L
A
A
A
E
A
S
F
D
P
R
K
T
W
---------
48
HHSearch
71.57
26%
-79
- C1 -
1NLT
3
MAS5_YEAST
A:
[8-235]
-----------------------------------------------------------------------------------------------------------------------------
P
Q
R
G
K
D
I
K
H
E
I
S
A
S
L
E
E
L
Y
K
G
R
T
A
K
L
A
L
N
K
Q
I
L
C
K
E
C
E
G
R
G
-
G
K
-
K
G
-
A
V
K
K
C
T
S
C
N
G
Q
G
----------------
I
K
F
V
T
R
Q
M
G
PM
I
Q
R
F
Q
T
---
E
C
D
V
C
H
-
G
T
G
D
I
I
--
D
PK
D
R
C
K
S
C
N
G
K
K
V
-
E
N
E
R
K
I
L
E
V
H
V
E
P
G
M
K
D
G
Q
R
I
V
F
K
G
E
A
D
Q
A
-
P
D
-
V
I
P
G
D
V
V
F
I
V
S
E
R
-
P
H
K
S
F
K
R
D
G
D
D
L
V
Y
E
A
E
I
D
L
L
T
A
I
A
G
G
E
F
A
L
E
H
V
S
G
D
W
L
K
V
G
I
V
P
G
EV
I
A
P
G
M
R
K
V
--
I
E
G
K
G
M
P
I
P
K
Y
-
G
G
Y
G
N
L
I
I
K
F
T
I
K
D
--
P
E
-----------------------------------
71
Fugue
69.56
25%
-82
* C1 *
3LZ8
-
?
A:
[113-302]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
R
G
H
D
--
L
--
E
I
E
V
A
V
---
F
L
E
E
T
L
A
E
Q
T
R
T
I
--
S
--
Y
N
L
P
V
Y
N
V
F
G
I
E
S
E
T
P
K
T
L
N
V
K
I
P
A
G
V
V
D
G
Q
R
I
R
L
K
G
Q
G
T
----
P
G
G
P
N
G
D
L
W
L
V
I
H
I
A
-
P
H
P
L
F
D
I
V
G
H
N
L
E
I
V
L
P
L
A
P
W
E
A
A
L
G
A
K
V
T
V
P
T
L
K
E
-
S
I
L
L
T
V
P
P
G
--
S
Q
A
G
Q
R
L
R
--
I
K
G
K
G
L
V
--
S
K
-
T
H
T
G
D
L
F
A
V
I
K
I
V
M
--
P
T
K
P
D
E
K
A
R
E
L
W
Q
Q
L
A
A
A
E
A
S
F
D
P
R
K
T
W
---------
49
HHSearch
67.43
21%
-93
- C1 -
3AGX
-
DNJB1_HUMAN
A:
[165-339]
------------------------------------------------------------------------------------------------------------------------------------
T
H
D
L
R
V
S
L
E
E
I
Y
S
G
C
T
K
K
M
K
I
S
H
K
R
L
N
P
D
-------------------------------------------------------------------------------------
G
K
S
I
-
R
N
E
D
K
I
L
T
I
E
V
K
K
G
W
K
E
G
T
K
I
T
F
P
K
E
G
D
Q
T
-
S
N
-
N
I
P
A
D
I
V
F
V
L
K
D
K
-
P
H
N
I
F
K
R
D
G
S
D
V
I
Y
P
A
R
I
S
L
R
E
A
L
C
G
C
T
V
N
V
P
T
L
D
G
R
T
I
P
V
V
F
K
D
V
--
I
R
P
G
M
R
R
K
--
V
P
G
E
G
L
P
L
P
K
T
P
E
K
R
G
D
L
I
I
E
F
E
V
I
F
--
P
E
R
I
P
Q
T
S
R
T
V
L
E
Q
V
L
P
I
-------------------
50
HHSearch
65.86
27%
-93
- C1 -
2Q2G
1
?
A:
[4-179]
---------------------------------------------------------------------------------------------------------------------------------
R
S
H
E
V
P
L
L
V
T
L
E
E
L
Y
L
G
K
R
K
K
I
K
V
T
R
K
R
F
I
E
H
---------------------------------------------------------------------------------------
K
V
-
R
N
E
E
N
I
V
E
V
E
I
K
P
G
W
K
D
G
T
K
L
T
Y
S
G
E
G
D
Q
E
-
S
P
G
T
S
P
G
D
L
V
L
I
I
Q
T
K
-
T
H
P
R
F
T
R
D
D
C
H
L
I
M
K
V
T
I
P
L
V
R
A
L
T
G
F
T
C
P
V
T
T
L
D
N
R
N
L
Q
I
P
I
K
E
I
--
V
N
P
K
T
R
K
I
--
V
P
N
E
G
M
P
I
K
N
Q
P
G
Q
K
G
D
L
I
L
E
F
D
I
C
F
--
P
K
S
L
T
P
E
Q
K
K
L
I
K
E
A
L
---------------------
24
PsiBlast_CBE
61.22
58%
-42
- C2 -
4J7Z
1
DNAJ2_THET8
B:
[2-98]
-
A
K
K
D
Y
Y
A
I
L
G
V
P
R
N
A
T
Q
E
E
I
K
R
A
Y
K
R
L
A
R
Q
Y
H
P
D
V
N
---
K
S
-
P
-
E
A
E
E
K
F
K
E
I
N
E
A
Y
A
V
L
S
D
P
E
K
R
R
I
Y
D
T
Y
G
T
T
E
A
PPPPP
P
G
G
Y
D
F
S
-
G
F
-
D
V
E
D
F
S
E
F
F
Q
E
L
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
61.00
58%
-46
- C2 -
4J7Z
-
DNAJ2_THET8
A:
[2-98]
-
A
K
K
D
Y
Y
A
I
L
G
V
P
R
N
A
T
Q
E
E
I
K
R
A
Y
K
R
L
A
R
Q
Y
H
P
D
V
N
---
K
S
-
P
-
E
A
E
E
K
F
K
E
I
N
E
A
Y
A
V
L
S
D
P
E
K
R
R
I
Y
D
T
Y
G
T
T
E
A
PPPPP
P
G
G
Y
D
F
S
-
G
F
-
D
V
E
D
F
S
E
F
F
Q
E
L
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
59.81
58%
-43
- C2 -
4J7Z
1
DNAJ2_THET8
C:
[2-98]
-
A
K
K
D
Y
Y
A
I
L
G
V
P
R
N
A
T
Q
E
E
I
K
R
A
Y
K
R
L
A
R
Q
Y
H
P
D
V
N
---
K
S
-
P
-
E
A
E
E
K
F
K
E
I
N
E
A
Y
A
V
L
S
D
P
E
K
R
R
I
Y
D
T
Y
G
T
T
E
A
PPPPP
P
G
G
Y
D
F
S
-
G
F
-
D
V
E
D
F
S
E
F
F
Q
E
L
F
G
-
P
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
59.54
58%
-47
- C2 -
4J7Z
1
DNAJ2_THET8
E:
[3-98]
--
K
K
D
Y
Y
A
I
L
G
V
P
R
N
A
T
Q
E
E
I
K
R
A
Y
K
R
L
A
R
Q
Y
H
P
D
V
N
---
K
S
-
P
-
E
A
E
E
K
F
K
E
I
N
E
A
Y
A
V
L
S
D
P
E
K
R
R
I
Y
D
T
Y
G
T
T
E
A
PPPPP
P
G
G
Y
D
F
S
-
G
F
-
D
V
E
D
F
S
E
F
F
Q
E
L
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
58.88
58%
-51
- C2 -
4J7Z
1
DNAJ2_THET8
F:
[2-98]
-
A
K
K
D
Y
Y
A
I
L
G
V
P
R
N
A
T
Q
E
E
I
K
R
A
Y
K
R
L
A
R
Q
Y
H
P
-----------
E
A
E
E
K
F
K
E
I
N
E
A
Y
A
V
L
S
D
P
E
K
R
R
I
Y
D
T
Y
G
T
T
E
A
PPPPP
P
G
G
Y
D
F
S
-
G
F
-
D
V
E
D
F
S
E
F
F
Q
E
L
F
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
HHSearch
57.09
23%
-94
- C1 -
1C3G
-
SIS1_YEAST
A:
[181-349]
----------------------------------------------------------------------------------------------------------------------------------
T
V
Q
V
N
L
P
V
S
L
E
D
L
F
V
G
K
K
K
S
F
K
I
G
R
K
G
P
H
G
-------------------------------------------------------------------------------------------
A
S
E
K
T
Q
I
D
I
Q
L
K
P
G
W
K
A
G
T
K
I
T
Y
K
N
Q
G
D
Y
N
-
P
Q
T
G
R
R
K
T
L
Q
F
V
I
Q
E
K
-
S
H
P
N
F
K
R
D
G
D
D
L
I
Y
T
L
P
L
S
F
K
E
S
L
L
G
F
S
K
T
I
Q
T
I
D
G
R
T
L
P
L
S
R
V
Q
P
--
V
Q
P
S
Q
T
S
T
--
Y
P
G
Q
G
M
P
T
P
K
N
P
S
Q
R
G
N
L
I
V
K
Y
K
V
D
Y
--
P
I
S
L
N
D
A
Q
K
R
A
I
D
------------------------
56
HHSearch
56.63
59%
-49
- C2 -
2DN9
-
A:
[5-75]
-
S
S
G
D
Y
Y
Q
I
L
G
V
P
R
N
A
S
Q
K
E
I
K
K
A
Y
Y
Q
L
A
K
K
Y
H
P
D
T
N
--
K
D
D
-
P
-
K
A
K
E
K
F
S
Q
L
A
E
A
Y
E
V
L
S
D
E
V
K
R
K
Q
Y
D
A
Y
G
S
G
P
S
-----
S
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
HHSearch
56.32
58%
-42
- C2 -
2DMX
-
DNJB8_HUMAN
A:
[8-80]
--
M
A
N
Y
Y
E
V
L
G
V
Q
A
S
A
S
P
E
D
I
K
K
A
Y
R
K
L
A
L
R
W
H
P
D
K
N
--
P
D
N
K
E
-
E
A
E
K
K
F
K
L
V
S
E
A
Y
E
V
L
S
D
S
K
K
R
S
L
Y
D
R
A
G
C
D
S
W
-----
R
A
G
G
G
A
S
G
P
S
S
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
56.29
64%
-48
- C2 -
2DMX
-
DNJB8_HUMAN
A:
[10-76]
----
N
Y
Y
E
V
L
G
V
Q
A
S
A
S
P
E
D
I
K
K
A
Y
R
K
L
A
L
R
W
H
P
D
K
N
--
P
D
N
-
K
E
E
A
E
K
K
F
K
L
V
S
E
A
Y
E
V
L
S
D
S
K
K
R
S
L
Y
D
R
A
G
C
D
S
W
-----
R
A
G
G
G
A
S
G
P
S
S
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
56.17
59%
-56
- C2 -
2DN9
-
A:
[8-79]
----
D
Y
Y
Q
I
L
G
V
P
R
N
A
S
Q
K
E
I
K
K
A
Y
Y
Q
L
A
K
K
Y
H
P
D
T
N
--
K
D
D
-
P
-
K
A
K
E
K
F
S
Q
L
A
E
A
Y
E
V
L
S
D
E
V
K
R
K
Q
Y
D
A
Y
G
S
G
P
S
-----
S
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
55.93
63%
-36
- C2 -
2EJ7
-
DNJB3_HUMAN
A:
[10-82]
----
D
Y
Y
E
V
L
D
V
P
R
Q
A
S
S
E
A
I
K
K
A
Y
R
K
L
A
L
K
W
H
P
D
K
N
--
P
E
N
-
K
E
E
A
E
R
R
F
K
Q
V
A
E
A
Y
E
V
L
S
D
A
K
K
R
D
I
Y
D
R
Y
G
S
G
P
S
-----
S
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
55.59
55%
-53
- C2 -
2CUG
-
DJC16_MOUSE
A:
[18-88]
----
D
P
Y
R
V
L
G
V
S
R
T
A
S
Q
A
D
I
K
K
A
Y
K
K
L
A
R
E
W
H
P
D
K
N
KD
P
G
-----
A
E
D
R
F
I
Q
I
S
K
A
Y
E
I
L
S
N
E
E
K
R
T
N
Y
D
H
Y
G
S
G
P
S
-----
S
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
55.44
61%
-88
- C2 -
4WB7
-
DNJB1_HUMAN (first)
A:
[2-69]
---
K
D
Y
Y
Q
T
L
G
L
A
R
G
A
S
D
E
E
I
K
R
A
Y
R
R
Q
A
L
R
Y
H
P
D
K
N
KE
P
G
-----
A
E
E
K
F
K
E
I
A
E
A
Y
D
V
L
S
D
P
R
K
R
E
I
F
D
R
Y
G
E
E
V
K
-----
E
F
L
A
K
A
K
E
D
F
L
K
K
W
E
S
P
A
Q
N
T
A
H
L
D
-
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
H
T
L
N
E
K
R
I
L
Q
A
V
-
N
F
-
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
----------------
L
Y
M
V
M
E
--
Y
--
V
P
G
G
E
M
---
F
S
H
L
R
R
-
I
G
R
F
S
E
--
P
--
H
A
R
F
Y
A
A
Q
I
V
L
-
T
F
E
Y
L
H
S
L
D
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
-
T
D
F
G
F
A
K
R
V
K
G
R
T
W
T
L
-
C
G
T
P
E
Y
L
A
P
E
I
I
L
S
K
G
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
F
A
D
Q
P
I
--
Q
I
Y
E
K
I
V
S
--
G
K
V
R
F
P
S
H
F
S
S
-
D
L
K
D
L
L
R
N
L
L
Q
V
D
L
T
K
R
F
G
N
L
K
N
G
V
N
D
I
K
N
H
K
W
F
A
T
T
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P