@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0100: (2015-12-12 )
METIEWNEEQRKAFQDLLREFVALIDAKVQEKKQMGKKPKIPKYASCQNGLNKFLAPWGYACKISLGTGLLSHEPSIAFCRQDILGEGFVNGEKPTPTKGFYLWFAYYWRNDLEKIDLCIGRSDEEDKKEECQKCLAYDKIIPNRNECYREL
Atome Classification :
(20 SA)
--.........10-----........20---......-...30------.......-------.40........50.....--...60......-------..70.....----...80...--.....90........100.......110.....-----..120.........130........140.......150-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--METIEW
N
E
E
Q
R
-----
K
A
F
Q
D
L
L
R
E
----
F
V
A
L
I
D
-
A
K
V
Q
E
------
K
K
QMGKK-------PKIP
K
Y
A
S
C
Q
N
G
L
N
K
F
L
A--PWG
Y
A
C
K
I
SLG-------TGLLSHEP
S
----
I
A
F
C
R
Q
D
I
--
L
GEGFVNGEKPTPTK
G
F
Y
L
W
F
A
Y
Y
W
RN
D
L
E
K
I
D
-----
L
CI--GRSD
E
E
D
K
K
E
E
-
C
Q
K
C
L
A
Y
D
KIIP
N
R
N
E
C
Y
REL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
91.77
19%
-74
- C6 -
3SSC
2
MCRB_ECOLI
A:
[2-155]
------------------
E
S
I
Q
P
W
I
E
K
----
F
I
K
Q
A
Q
-
Q
Q
-----------
R
S
Q
S
T
-------
K
D
Y
P
T
S
Y
R
--------------
N
L
R
V
K
L
S
F
G
-------
Y
G
N
F
T
S
I
P
W
----
F
A
F
L
G
E
G
Q
-------------
E
A
S
N
G
I
Y
P
V
I
L
Y
Y
--
K
D
F
D
E
L
V
-----
L
A
Y
--
G
I
S
D
T
N
E
P
H
A
Q
-
W
Q
F
S
S
D
I
P
K
T
I
A
E
Y
F
Q
A
T
S
G
V
YPKKYGQSYYACSQKVSQGID
Y
T
R
F
A
S
M
L
D
N
I
I
N
D
Y
K
L
I
F
N
S
G----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
78.44
25%
-115
- C6 -
3SSC
2
MCRB_ECOLI
A:
[3-86]
-------------------
S
I
Q
P
W
I
E
K
----
F
I
K
Q
A
Q
Q
Q
R
S
Q
-----------
S
T
K
-------
D
Y
P
T
S
Y
R
---------------
N
L
R
V
K
L
S
F
G
-------
Y
G
N
F
T
S
I
P
W
----
F
A
F
L
G
E
-------------
G
Q
E
A
S
N
G
I
Y
P
V
I
L
Y
Y
--
K
D
F
D
E
L
V
-----
L
A
Y
--
G
I
S
D
T
N
E
P
H
A
Q
-
W
Q
F
S
S
D
I
P
K
T
I
A
E
Y
F
Q
A
T
S
G
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
68.80
9%
-51
- C6 -
2V1O
2
BACH_MOUSE
A:
[1-149]
---
G
A
M
R
I
M
R
P
D
D
ANVAG
N
V
H
G
G
T
I
L
K
----
M
I
E
E
A
G
-
A
I
I
S
T
------
R
H
C
N
S
Q
N
-------
G
E
R
C
V
A
A
L
A
R
V
E
R
T
D
F
L
S
--
P
M
C
I
G
E
V
A
H
V
S
-------
A
E
I
T
Y
T
S
K
H
----
S
V
E
V
Q
V
H
V
--
M
S
E
N
I
L
T
G
T
K
K
L
T
N
K
A
T
L
W
Y
V
P
L
S
L
K
N
V
D
K
V
L
E
-----
V
P
P
--
I
V
Y
L
R
Q
E
Q
E
E
E
-
G
R
K
R
Y
E
A
Q
K
L
E
R
M
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
55.21
9%
-55
- C6 -
3A1Y
-
RL10_PYRHO
G:
[1-284]
-M
A
H
V
A
E
W
K
K
K
E
V
-----
E
E
L
A
K
L
I
K
S
YPVI
A
L
V
D
V
S
-
S
M
P
A
Y
------
P
L
S
Q
M
R
R
-------
L
I
R
E
N
G
G
L
L
R
V
S
R
N
T
L
I
E
--
L
A
I
K
K
A
A
K
E
L
G
KPELEKL
V
E
Y
I
D
R
G
A
G
----
I
L
V
T
N
M
N
P
FK
L
Y
K
F
L
Q
Q
N
R
Q
P
Q
P
L
E
V
G
L
D
V
L
A
V
Y
E
D
G
I
V
Y
T
P
D
-----
V
L
A
ID
E
Q
E
Y
I
D
M
L
Q
K
A
-
Y
M
H
A
F
N
L
A
V
N
I
A
Y
P
T
P
E
T
I
E
A
IIQKAFLNAKTVAIEAGYITKETIQDIIGRAFRAMLLLAQQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
54.29
13%
-14
- C6 -
1LFW
3
PEPV_LACDL
A:
[1-468]
MD
L
N
F
K
E
L
A
E
A
K
K
-----
D
A
I
L
K
D
L
E
E
----
L
I
A
-
I
D
-
S
S
E
D
L
------
E
N
A
T
E
E
Y
-------
P
V
G
K
G
P
V
D
A
M
T
K
F
L
S
F
A
K
--
R
D
G
F
D
T
E
N
F
A
N
Y------
A
G
R
V
N
F
G
A
G
D
K
R
L
G
I
I
G
H
M
D
V
--
V
P
A
G
-------------
E
G
W
T
R
D
P
F
K
M
E
I
D
E
E
G
-----
R
I
Y
--
G
R
G
S
A
D
D
K
G
P
S
-
L
T
A
Y
Y
G
M
L
L
L
K
E
A
G
F
K
P
K
K
K
I
DF
V
L
G
TNEETNW
V
G
I
D
Y
Y
L
K
H
E
PTPD
I
V
F
S
PDAEYPIINGE
Q
G
I
F
T
L
E
F
S
F
K
N
DDTKGDYVLD
K
F
K
A
G
IATNVTPQ
V
T
R
A
T
I
S
G
P
D
L
E
A
V
K
L
A
Y
E
S
F
L
A
D
K
E
L
D
G
S
F
E
I
NDE
S
A
D
I
V
L
I
G
Q
G
A
HASAPQVGKN
S
A
T
F
L
A
L
F
L
D
Q
YAFAG
R
D
K
N
F
L
H
F
L
A
EVEHEDFYGKKLGI
F
H
H
D
DLM
G
D
L
A
S
S
P
S
M
F
D
Y
E
HAGKA
S
L
L
N
N
V
R
Y
P
QGTD
P
D
T
M
I
K
Q
V
L
D
K
FSGI
L
D
V
T
Y
N
G
FE
E
P
H
Y
V
PGSD
P
M
V
Q
T
L
L
K
V
Y
E
K
Q
T
G
K
P
G
H
E
V
V
I
GGGTYGRLFER
G
V
A
F
G
AQPENGPMVMHAAN
E
F
M
M
L
D
D
L
I
L
S
I
A
I
Y
A
E
A
I
Y
E
L
T
KDE
22
Fugue
51.42
18%
70
- C4 -
1JJ2
-
RL32_HALMA
X:
[95-236]
--
T
E
L
Q
A
R
G
L
T
E
K
-----
T
P
D
L
S
--
D
E
----
D
A
R
L
L
T
-
Q
R
H
R
V
------
G
K
P
Q
F
N
R
-------
Q
D
H
H
K
K
K
R
V
S
T
S
W
R
K
-----
P
R
G
Q
L
S
K
Q
R
R
G
-------
I
K
G
K
G
D
T
V
E
----
A
G
F
R
S
P
T
A
--
V
R
G
K
H
P
S
G
F
E
E
V
R
V
H
N
---------
V
D
D
L
E
G
V
D
GDT
E
A
V
R
I
--
A
S
K
V
G
A
R
K
R
E
R
-
I
E
E
-
E
A
E
D
A
G
I
R
V
L
N
P
T
Y
V
E
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
49.39
39%
-37
- C6 -
3IEY
-
ENDA_NANEQ
A:
[22-66]
-------------------------------------------------------------------------------------------------------------------------------------------------
A
Y
Y
L
---
L
D
K
G
E
-----
L
E
V
--
Y
E
D
D
K
----
E
E
F
L
K
K
C
L
T
Y
D
E
R
F
L
I
R
Y
K
A
Y
K
E
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
45.35
28%
-37
- C6 -
3AJ1
-
ACSD_KOMXY
A:
[6-73]
-----------
K
K
-----
P
D
F
T
L
F
L
Q
T
----
L
S
W
E
I
D
-
D
Q
V
G
I
E
V
R
N
E
L
L
R
E
V
G
R
G
M
G
T
R
I
MP
P
P
C
Q
T
V
D
K
L
Q
I
E
L
N
A
L
L
A
L
I
G
W
G
T
V
T
L
E
L
L
S
-------
E
D
Q
S
L
R
I
V
H
----
E
N
L
P
Q
V
G
S
--
A
G
E
P
S
G
T
W
L
A
P
V
L
E
G
L
Y
G
R
W
V
T
S
Q
A
G
A
F
G
D
Y
V
V
-----
T
R
D
--
V
D
A
E
D
L
N
A
V
P
R
-
Q
T
I
I
M
Y
M
R
V
R
S
S
A
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
44.93
40%
-33
- C6 -
3JS8
-
?
A:
[366-395]
-----------
R
R
-----
E
N
V
Q
R
V
L
N
E
----
F
V
T
F
Y
Q
-
A
R
V
Q
A
------
Y
Q
Q
Q
G
R
Y
-------
P
M
N
G
P
V
E
I
R
V
T
G
L
D
D
P
S
E
--
A
A
L
S
G
G
V
A
P
A
L
-------
S
A
I
R
P
R
P
D
H
----
P
E
W
N
V
A
V
W
--
L
D
I
L
T
L
P
G
T
P
Y
A
N
Q
F
Y
R
E
I
E
Q
W
I
E
A
N
F
N
G
S
Y
A
A
-----
V
R
P
--
E
W
S
K
G
W
G
Y
T
D
Q
-
A
A
W
A
D
S
A
M
L
Q
T
T
I
P
N
A
F
R
A
G
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
44.16
22%
-5
- C6 -
1TQY
-
KASB_STRCO
B:
[152-237]
-----
I
S
I
R
H
G
M
R
-----
G
P
S
S
A
L
V
A
E
----
Q
A
G
G
L
D
-
A
L
G
H
A
------
R
R
T
I
R
R
G
-------
T
P
L
----
V
V
S
G
G
V
D
S
A
L
D
--
P
W
G
W
V
S
Q
I
A
S
G
-------
R
I
S
T
A
T
D
P
D
----
R
A
Y
L
P
F
D
E
--
R
A
A
G
Y
V
P
G
E
G
G
A
I
L
V
L
E
D
S
A
A
A
E
A
R
G
R
H
D
A
Y
G
E
-----
L
A
G
--
C
A
S
T
F
D
P
A
P
G
S
-
G
R
P
A
G
L
E
R
A
I
R
L
A
L
N
D
A
G
T
G
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
42.17
18%
19
- C6 -
4WY4
-
B:
[1-58]
---
E
S
W
E
T
L
E
A
D
L
-----
I
E
L
S
Q
L
V
T
D
----
F
S
L
L
V
N
-
S
Q
-
Q
E
------
K
I
D
S
I
A
D
-------
H
V
N
S
A
A
V
N
V
E
E
G
T
K
N
L
G
K
--
A
A
K
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
38.59
24%
29
- C6 -
4UOT
-
?
A:
[4-34]
-------
T
Q
E
Y
L
L
-----
K
E
I
M
K
L
L
K
E
----
Q
I
K
L
L
K
-
E
Q
I
K
M
------
L
K
E
L
E
K
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
32.96
15%
-6
- C6 -
3LAY
-
ZRAP_SALTY
A:
[44-66]
-------
L
T
T
E
Q
Q
-----
A
T
A
Q
K
I
Y
D
D
----
Y
Y
T
Q
T
S
-
A
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
32.71
30%
21
- C6 -
2YQK
-
A:
[10-29]
-----
K
C
W
T
E
D
E
V
-----
K
R
F
V
K
G
L
R
Q
----
Y
G
K
N
F
F
-
R
I
R
K
E
------
L
L
P
N
K
E
T
-------
G
E
L
I
T
F
Y
Y
Y
W
K
K
T
S
G
P
S
S
--
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
31.84
11%
16
* C6 *
2AXT
117
PSBM_THEEB
M:
[1-36]
--
M
E
V
N
Q
L
G
L
I
A
T
-----
A
L
F
V
L
V
P
S
V
----
F
L
I
I
L
Y
-
V
Q
T
E
S
------
Q
Q
K
S
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
30.81
35%
-32
- C6 -
2IGP
2
A:
[16-38]
--------------------------------------------------------------------
I
Q
Q
C
I
R
Q
L
C
E
F
L
T
--
E
N
G
Y
A
H
N
V
S
M
K
-------
S
L
Q
A
P
S
V
K
D
----
F
L
K
I
F
T
F
L
--
Y
G
F
L
C
P
S
Y
E
L
P
D
T
K
F
E
E
E
V
P
R
I
F
K
D
L
G
Y
P
F
A
L
S
-----
K
S
S
--
M
Y
T
V
G
A
P
H
T
W
P
-
H
I
V
A
A
L
V
W
L
I
D
C
I
K
I
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
30.03
21%
31
- C6 -
2QGU
1
?
A:
[90-108]
--------
T
P
E
Q
Q
-----
Q
Q
I
Q
D
G
F
K
S
----
L
L
I
R
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
29.89
11%
-17
- C6 -
2WVQ
-
HETS_PODAS
A:
[148-174]
---
K
K
T
A
W
A
L
Y
D
G
-----
K
S
L
E
K
I
V
D
Q
----
V
A
R
F
V
D
-
E
L
E
K
A
------
F
P
I
E
A
V
C
-------
H
K
L
A
E
I
E
I
E
E
V
E
D
E
A
S
L
T
--
I
L
K
D
A
A
G
G
I
D
A
-------
A
M
S
D
A
A
A
Q
K
----
I
D
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
27.61
15%
-4
- C6 -
3WLA
-
OPH_SPHS1
A:
[286-312]
------
M
W
P
Q
V
N
T
-----
D
A
F
N
L
W
A
L
N
----
T
M
A
S
H
P
-
K
G
S
S
P
------
K
D
F
K
L
T
A
-------
P
P
E
G
Y
S
C
K
I
G
R
F
T
D
H
Y
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
26.14
33%
-24
- C7 -
2AXI
1
MDM2_HUMAN
A:
[53-70]
---------------------------------------------------------------------------------------------------------
E
K
Q
Q
H
----
I
V
Y
C
S
N
D
L
--
L
G
D
L
F
G
V
P
S
F
S
V
K
E
H
R
K
I
Y
T
M
I
Y
R
N
L
V
V
V
N
Q
Q
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------