@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0120: (2015-12-12 )
MASFSILSIFKIGVGPSSSHTIGPMEAGARFCGLLKGILEQVERVQITLHGSLALTGKGHLSDEAVLIGLHGIYANELDITTKKALLHEAFENKVLKLANQHHIPFDYAKDLIFDNKPLARHQNALILKAFNAKNEVLKEETYYSVGGGFVYTEKELDNLSEEGENESVAYDFSSAKELLELCQKHQKSIAEIVRLRENALKNHPDATMTKIYHAMLECYHNGANSKERYLPGSLKVTRLAPSVKTRLEKHPTSGKDPLALIDYISLYARSIAEENASGGKVVTAPTNGACAVVPSVLSYAKNHLFENLSQKSINDFLLTSAAIGYLYKKNASLSGAEAGCQAEIGVASSMAAGGLAHLCQATTQQVLIASEIAMEHHLGLTCDPVGGLVQIPCIERNVLGAIKAISASKLALEDEYKPKVSLDEVIATMYATGKDMNEKYKETSLGGLAKTLKC
Atome Classification :
(20 SA)
.........10........-20...-.....30----------.....--.----.--..40....--....50...-.....60.---------------------.......70......-..80...------......90.-------.......100.--...-...110.....--.-.-120...----....130.......140-----...---....-150---........160..---.....170..-----------------.....180.......190..-----.....200----....--...----210.-...------------------------...------------220-.....-----------.-.230.....-------..240......-.250.......260.--.......270..-.....280...---.----...290.......300.------...--------...310.---......320.......330........340.......350...-.....360........370.......380.-.---.....390.......400.......410.......420.......430....-...440.......450....---------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAS
F
S
I
L
S
I
F
K
IGVGPSSS-HTI
G
P
-
M
E
A
G
A
R
-----------
F
C
G
L
L
--
K
----
G
--
I
L
E
Q
V
E
R
V
--
Q
I
T
L
H
G
S
L
A
-
L
TGKGHLS---------------------D
E
A
V
L
I
G
L
H
G
IYANE-LDI-
T
T
K
------
K
A
L
L
H
E
A
F
E
-------
N
K
V
L
K
L
A
NQHH--I
P
F
-
D
Y
A
K
D
L
IFDNK--P-L-ARHQ
N
A
----
L
I
L
K
AFNAK
N
E
V
L
K
EET-----
Y
Y
S---VGG
G
-
F
V
----
Y
T
E
K
E
L
DNLSEEG---ENE
S
V
A
Y
D
F
S
-----------------
S
A
K
E
L
L
E
L
C
Q
K
H
Q
K
S
I
A
E
I
V
-----
R
L
R
E
N
A
LK----NHP
D
--
A
T
M
----
T
K
I
Y
-
H
A
M
------------------------
L
E
C
------------
Y
HN-GANSK-----------E-RYLPGS
L
K
V
-------
T
R
LA
P
S
V
K
T
R
L
-
E
KHPTSGKD
P
L
A
-
L
I
--
D
Y
I
S
L
Y
A
R
S
I
A
E
-ENASG
G
K
V
V
TA---P----TNG
A
C
A
V
V
P
S
V
L
S
Y
A
K
N
------
H
L
F
--------
E
N
L
S
Q
K
S
---
I
N
D
F
L
L
T
S
A
A
I
G
Y
L
Y
KK-NASLSGAEAGC
Q
A
EIGV
A
S
S
-
M
A
A
G
-
G
L
A
H
L
C
-
Q
A
T
T
Q
Q
V
L
I
A
S
E
I
A
M
E
HHLGLTC-D---PVG
G
L
V
QIPCIE
R
N
V
L
G
A
I
K
A
ISASKLALEDEYKPKV
S
L
D
E
V
I
A
T
M
YATGK
D
-
M
N
E
K
Y
K
E
T
S
L
G
G
L
A
K
-TLKC---------------------------------------
1
PsiBlast_PDB
90.04
43%
-84
- C4 -
4RQO
1
?
A:
[20-473]
--
N
I
S
V
F
D
L
F
S
I
G
I
G
P
S
S
S
-
H
T
V
G
P
-
M
L
A
A
N
A
-----------
F
L
Q
L
L
E
Q
K
----
N
--
L
F
D
K
T
Q
R
V
--
K
V
E
L
Y
G
S
L
A
-
L
T
G
K
G
H
G
T
---------------------
D
K
A
I
L
N
G
L
E
N
K
A
P
E
T
-
V
D
P
-
A
S
M
------
I
P
R
M
H
E
I
L
D
-------
S
N
L
L
N
L
A
G
K
K
E
--
I
P
F
-
H
E
A
T
D
F
L
F
L
Q
K
--
E
-
L
L
P
K
H
S
N
G
----
M
R
F
S
A
F
D
G
N
A
N
L
L
I
E
Q
V
-----
Y
Y
S
---
I
G
G
G
-
F
I
----
T
T
E
E
D
F
D
K
----------
N
P
P
P
Y
P
F
A
-----------------
T
A
T
E
L
L
K
L
C
K
K
H
H
L
T
I
A
E
L
M
-----
L
V
N
E
K
T
W
R
----
S
T
A
E
I
H
K
G
I
----
L
D
I
A
-
K
V
M
------------------------
D
D
C
------------
I
N
N
-
G
C
-
K
H
-----------
D
-
G
V
L
P
G
G
L
N
L
-------
K
R
R
A
P
D
L
Y
R
K
L
I-------
F
E
Q
S
D
-
I
M
--
N
H
L
N
L
Y
A
M
A
V
N
E
-
E
N
A
A
G
G
R
I
V
T
A
---
P
----
T
N
G
A
A
G
I
I
P
A
V
L
K
Y
C
Q
-------
Q
A
H
--------
D
R
M
S
N
E
D
---
I
Y
T
Y
F
L
T
A
A
A
I
G
I
L
Y
K
K
-
G
A
S
I
S
G
A
E
V
G
C
Q
G
E
V
G
V
A
S
S
-
M
A
A
A
-
G
L
T
A
V
L
-
G
G
T
I
E
Q
V
E
N
A
A
E
I
A
M
E
H
H
L
G
M
T
C
-
D
---
P
V
L
G
L
V
Q
I
P
C
I
E
R
N
A
M
G
A
V
K
A
V
N
A
T
R
M
A
L
I
G
D
G
Q
H
Q
I
S
L
D
K
V
I
K
T
M
K
Q
T
G
M
D
-
M
Q
S
I
Y
K
E
T
S
M
G
G
L
A
V
-
N
L
P
E
---------------------------------------
31
Fugue
53.03
42%
-68
- C4 -
2IAF
1
?
A:
[7-151]
-----------------
S
S
-
H
T
V
G
P
M
L
-
A
A
N
A
-----------
F
L
Q
L
L
--
E
Q
K
--
N
--
L
F
D
K
T
Q
R
V
--
K
V
E
L
Y
G
S
L
A
-
L
T
G
K
G
H
G
T
---------------------
D
K
A
I
L
N
G
L
E
N
K
A
P
E
S
M
I
P
R
M
H
-------------
E
I
L
D
-------
S
N
L
L
N
L
A
G
K
K
E
--
I
P
F
-
H
E
A
T
D
F
L
F
L
Q
K
--
E
L
L
-
P
K
H
S
N
G
M
---
R
F
S
-
A
F
D
G
N
A
N
L
L
I
E
Q
V
-----
Y
Y
S
---
I
G
G
G
-
F
I
----
T
T
E
E
D
F
D
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
52.82
43%
-64
- C4 -
2IAF
1
?
A:
[7-149]
-----------------
S
S
-
H
T
V
G
P
-
M
L
A
A
N
A
-----------
F
L
Q
L
L
--
E
----
Q
K
N
L
F
D
K
T
Q
R
V
--
K
V
E
L
Y
G
S
L
A
-
L
T
G
K
G
H
G
T
---------------------
D
K
A
I
L
N
G
L
E
N
K
A
P
E
-------
S
M
------
I
P
R
M
H
E
I
L
D
-------
S
N
L
L
N
L
A
G
K
K
E
--
I
P
F
-
H
E
A
T
D
F
L
F
L
Q
K
E-
L
-
L
-
P
K
H
S
N
G
----
M
R
F
S
A
F
D
G
N
A
N
L
L
I
E
Q
V
-----
Y
Y
S
---
I
G
G
G
-
F
I
----
T
T
E
E
D
F
D
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
52.69
42%
-64
- C4 -
2IAF
1
?
A:
[7-150]
-----------------
S
S
-
H
T
V
G
P
-
M
L
A
A
N
A
-----------
F
L
Q
L
L
E
Q
K
----
N
--
L
F
D
K
T
Q
R
V
--
K
V
E
L
Y
G
S
L
A
-
L
T
G
K
G
H
G
T
---------------------
D
K
A
I
L
N
G
L
E
N
K
A
P
E
-------
S
M
------
I
P
R
M
H
E
I
L
D
-------
S
N
L
L
N
L
A
G
K
K
E
--
I
P
F
-
H
E
A
T
D
F
L
F
L
Q
K
--
E
L
L
-
P
K
H
S
N
G
----
M
R
F
S
A
F
D
G
N
A
N
L
L
I
E
Q
V
-----
Y
Y
S
---
I
G
G
G
-
F
I
----
T
T
E
E
D
F
D
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
51.33
42%
-71
- C4 -
2IQQ
1
?
A:
[17-160]
-----------------
S
S
-
H
T
V
G
P
-
M
L
A
A
N
A
-----------
F
L
Q
L
L
E
Q
K
----
N
--
L
F
D
K
T
Q
R
V
--
K
V
E
L
Y
G
S
L
A
-
L
T
G
K
G
H
G
T
---------------------
D
K
A
I
L
N
G
L
E
N
K
A
P
E
T
-
V
D
P
-
A
S
M
------
I
P
R
M
H
E
I
L
D
-------
S
N
L
L
N
L
A
G
K
K
E
--
I
P
F
-
H
E
A
T
D
F
L
F
L
Q
K
--
E
L
L
-
P
K
H
S
N
G
----
M
R
F
S
A
F
D
G
N
A
N
L
L
I
E
Q
V
-----
Y
Y
S
---
I
G
G
G
-
F
I
----
T
T
E
E
D
F
D
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
46.35
18%
-58
* C3 *
4PQG
2
?
A:
[6-511]
H
H
H
M
T
I
Y
N
I
N
-
L
G
I
G
W
A
S
S
----
G
V
-
E
Y
A
Q
A
Y
-----------
R
A
G
V
F
--
R
----
K
--
L
N
L
S
S
K
F
I
F
T
D
M
I
L
A
D
N
I
Q
H
L
T
A
N
I
G
F
D
---------------------
D
N
Q
V
I
W
----
L
Y
N
H
F
-
T
D
I
-
K
I
A
PTSVT
V
D
D
V
L
A
Y
F
G
G
-------
E
E
S
H
R
E
K
N
G
K
V
--
L
R
V
-
F
F
F
D
Q
D
K
F
V
T
C
--
Y
-
L
-
V
D
E
N
K
D
----
L
V
Q
H
A
E
Y
V
F
K
G
N
L
I
R
K
D
-----
Y
F
S
YTR
Y
C
S
E
-
Y
F
----
A
P
K
D
N
V
A
V
L
Y
Q
R
T
F
Y
N
E
D
G
T
P
V
Y
D
I
L
-----------------
M
N
Q
G
K
E
E
V
Y
H
F
K
D
K
I
F
Y
G
K
Q
-----
A
F
V
R
A
F
M
K
S
L
NL
N
K
S
D
--
L
V
I
L
DRE
T
G
I
G
-
Q
V
V
------------------------
F
E
E
A
Q
T
A
H
L
A
V
V
V
H
A
E
H
Y
-
S
E
N
A
T
NED
Y
I
L
W
NNYY
D
-
Y
Q
F
T
N
A
D
K
V
D
F
F
I
V
ST
D
R
Q
N
E
V
L
Q
E
Q
F
-
A
K
Y
-
T
Q
H
Q
P
K
I
V
-
T
I
--
P
V
G
S
I
D
S
L
T
D
S
S
-
Q
G
R
K
P
F
S
L
I
T
A
---
S
RLAK
E
K
H
I
D
W
L
V
K
A
V
I
E
A
H
K
E
L
PE
L
T
F
D
I
Y
G
-------
S
G
G
E
D
S
L
---
L
R
E
I
I
A
N
H
Q
A
E
D
Y
I
Q
L
K
G
H
A
E
L
S
--
Q
I
Y
S
Q
Y
E
V
Y
L
T
A
S
-
T
S
E
G
F
G
L
T
L
M
E
-
A
I
G
S
G
L
P
L
I
G
F
D
V
P
Y
G
N
Q
T
F
I
E
D
-
G
---
Q
N
G
--
Y
L
I
P
S
S
S
D
H
V
E
D
Q
I
K
Q
A
Y
A
A
K
I
C
Q
L
Y
Q
E
N
R
---
L
E
A
M
R
A
Y
S
Y
Q
I
A
E
G
F
L
T
K
E
I
L
E
K
W
K
K
T
V
E
E
-
V
L
H
D
---------------------------------------
38
Fugue
40.64
19%
-41
* C5 *
4OOU
1
?
A:
[20-383]
-
S
E
F
L
K
A
S
--------
G
S
N
-
F
Y
Y
G
G
-
Q
K
V
-----------------
F
L
--
S
----
G
---------
V
--
N
F
A
W
R
S
Y
G
S
-
D
F
G
N
G
Q
Y
A
---------------------
S
N
G
P
A
L
K
D
W
I
N
K
V
K
A
-
S
G
G
-
N
T
A
------
R
V
W
V
H
--
V
E
-------
G
Q
V
S
P
A
F
D
S
H
G
FV
T
S
T
-
D
S
K
K
T
L
I
N
D
L
S
--
D
-
L
-
L
D
Y
A
N
G
Q
N
V
F
L
I
L
V
L
F
N
G
A
L
Q
--------------------------------------------
N
N
S
N
V
Q
N
L
F
W
-----------------
D
E
S
K
L
N
S
Y
I
N
N
---
A
L
T
P
M
V
---------
N
A
L
K
----
S
K
P
S
--
L
A
A
----
W
E
V
L
-
N
E
P
------------------------
E
G
T
------------
L
Q
P
-
G
S
D
Q
N
-----------
S
-
C
Y
D
T
S
T
L
A
A
-------
Q
G
A
G
W
G
-----------
G
K
K
F
P
M
K
Q
I
L
--
K
T
I
N
W
I
S
S
A
I
H
N
-
A
D
S
K
A
L
V
T
V
G
S
---
W
----
S
E
L
T
Q
T
D
S
F
G
Y
R
N
H
Y
K
D
------
S
C
L
--------
T
G
A
G
G
K
S
NGI
I
N
F
Y
Q
M
H
T
Y
S
H
S
G
K
W
N
Q
-
N
A
P
F
K
V
N
----
R
W
A
Y
N
V
N
D
K
P
L
L
I
G
-
E
F
A
S
V
C
S
Q
N
E
G
I
Q
N
L
Y
K
Y
A
Y
N
N
G
Y
N
G
A
L
T
W
-
Q
---
F
N
S
G
G
---
D
C
----------------------------
S
D
T
Y
S
N
Q
M
Y
G
M
Q
A
L
-
K
G
Q
N
D
Q
S
G
G
K
G
G
M
V
S
V
N
I
N
H
---------------------------------------
36
Fugue
35.80
11%
-20
- C1 -
3W6W
2
?
A:
[4-620]
G
S
P
Y
L
I
T
G
I
P
K
D
P
K
H
P
L
P
I
R
K
D
I
D
D
-
W
Y
L
E
Q
T
SAGSNR
I
Q
L
T
L
F
V
E
A
L
--
T
----
V
--
I
Q
N
R
P
L
N
D
--
Q
L
S
Y
F
R
L
A
G
-
I
H
G
A
P
W
T
E
WDGVPGGQKDSKGNPTGFCVH
N
N
Y
T
F
P
T
W
H
R
V
Y
V
T
L
-
Y
E
Q
-
V
I
Y
------
E
A
M
L
D
F
I
K
Q
NVPQNG
K
A
D
W
E
N
E
A
K
Q
W
R
--
L
P
Y
W
D
F
A
R
F
A
R
G
D
E
L
R
L
P
-
I
-
L
V
T
M
P
M
----
V
K
V
L
V
P
G
Q
P
G
K
Q
L
S
K
P
N
PLY
R
F
Q
M
Q
---
T
L
M
G
-
T
L
----
E
R
P
Y
A
I
T
S
Q
K
T
E
E
---
H
G
W
S
F
D
L
P
F
D
KCQ
S
T
T
K
YGLLENYNAD
V
W
A
D
G
G
Q
N
W
L
R
A
N
L
A
L
N
E
H
P
-----
W
Y
Q
N
L
D
G
W
----
D
S
V
P
--
T
L
Q
----
D
M
T
F
-
R
L
L
T
TGGLN
W
G
E
F
S
STRYDDAPKNWMN
L
E
A
------------
I
H
N
-
N
V
H
N
W
-----------
V
G
G
F
M
F
S
R
P
G
R
-------
H
D
L
K
L
W
G
A
G
H
M
-
S
S
V
P
V
A
A
Y
D
P
I
F
-
W
L
--
H
H
C
N
I
D
R
L
T
A
I
W
-
Q
T
V
N
S
G
S
W
F
N
----
D
----
D
K
S
K
V
S
K
D
D
D
L
R
P
F
H
R
F
------
C
E
K
--------
T
R
K
V
V
F
F
---
R
S
D
D
V
K
D
W
R
S
L
N
Y
D
Y
A
I
-
T
K
D
A
S
R
I
R
K
E
I
S
D
L
Y
G
Q
R
T
K
-
E
V
Y
K
-
D
F
G
E
E
D
-
Y
I
L
S
I
R
Y
S
R
Y
A
L
G
G
K
P
F
Q
I
N
I
F
F
-
G
---
D
V
D
G
K
D
F
Y
D
A
R
S
Q
N
F
V
G
S
V
F
N
F
S
G
S
L
E
D
S
N
C
D
K
C
A
V
L
S
V
S
Q
L
P
A
R
L
A
V
H
Y
Y
K
-
K
Q
N
K
G
E
V
P
T
P
R
Y
V
V
V
-
N
S
Q
G
KAEAE
V
K
V
E
V
A
L
H
K
T
E
G
TFYDYRRV
A
D
G
K
R
A
E
V
D
DAYRA
35
Fugue
35.70
21%
-9
- C3 -
4DQJ
2
?
A:
[14-150]
--------------------------------------------------------------------------------------------------------------------------------
S
R
------
V
R
F
T
T
A
E
V
D
-------
S
A
V
A
R
I
S
Q
K
I
G
--
V
P
A
-
S
Y
Y
Q
F
L
I
P
I
E
--------------------------
N
F
V
V
A
G
G
F
-----
E
T
T
---
V
S
G
S
-
F
R
GLGQ
F
N
R
Q
T
W
D
G
L
R
R
L
G
---
R
N
--------------------------
L
P
A
F
E
E
G
S
A
Q
L
N
A
S
L
Y
A
I
G
-----
F
L
Y
L
E
N
K
R
----
A
Y
E
A
--
S
F
K
----
G
R
V
F
T
H
E
I
------------------------
A
Y
L
------------
Y
H
N
Q
G
A
P
A
A
-----------
E
-
Q
Y
L
T
S
G
R
L
V
-------
Y
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
35.10
13%
-46
- C4 -
2HP0
2
?
A:
[121-241]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
S
L
V
P
A
I
F
A
V
-
G
E
------
H
V
----------
G
A
N
G
H
N
---
C
L
K
S
Y
V
L
G
I
E
V
V
A
T
L
G
R
-
A
V
G
K
G
H
Y
L
A
G
W
H
-
P
T
S
T
L
G
V
F
G
A
T
T
-
A
A
A
L
L
L
-
G
A
D
E
E
Q
L
R
N
A
W
G
I
A
A
S
N
S
C
G
I
I
K
N
F
---
G
T
-----
M
T
K
P
M
H
T
G
S
A
A
R
N
G
V
L
S
A
W
L
S
M
Q
S
F
T
G
C
Q
T
V
F
D
D
A
E
G
I
L
A
M
Y
G
A
Q
-
P
G
P
E
L
F
N
A
M
Q
K
F
G
T
P
-
W
A
I
I
---------------------------------------
39
Fugue
34.33
21%
0
- C5 -
3J7W
-
CAPSA_BPT7
A:
[2-344]
-------
A
S
M
T
G
G
Q
Q
M
G
T
N
-
Q
G
K
G
V
-
V
A
A
G
D
K
-----------
L
A
L
F
L
--
K
V
F
G
G
E
--
V
L
T
A
F
A
R
T
--
S
V
T
T
S
R
H
M
V
-
R
S
I
S
S
G
K
S
---------------------
A
Q
F
P
V
L
G
-------------
R
T
Q
------
A
A
Y
L
A
P
G
----------------------------------
E
N
L
--
D
-
D
-
K
R
K
D
I
K
----
H
T
E
K
V
I
T
I
D
G
L
L
T
A
D
V
L
-----
I
Y
D
---
I
E
D
A
-
M
N
----
H
Y
D
V
R
S
E
Y
T
S
Q
L
G
---
E
S
L
A
M
A
A
D
G
A
-----------------
V
L
A
E
I
A
G
L
C
N
V
E
S
K
Y
N
E
N
I
E
-----
G
L
----------------
G
T
A
----
T
V
I
------------------------------
E
T
------------
T
Q
N
-
K
A
A
L
T
-----------
D
-
Q
-
V
A
L
G
K
E
I
-------
I
A
A
L
T
K
A
R
A
A
L
-
T
K
N
Y
V
P
A
A
D
R
V
F
-
Y
C
--
D
P
D
S
Y
S
A
I
L
A
A
L
M
P
N
A
A
N
Y
A
A
L
I
D
---
P
----
E
K
G
S
---
I
R
N
V
M
G
F
-------------------------------------------------------------
E
V
V
E
V
P
H
-
L
T
A
G
-
G
A
G
T
A
R
-
E
G
T
T
G
Q
K
H
V
F
P
A
N
K
G
E
G
N
V
K
V
A
K
-
D
---
N
V
I
G
L
F
M
----
H
R
S
A
V
G
T
V
K
L
---
R
D
L
A
L
E
R
A
R
R
A
N
F
Q
A
D
Q
I
I
A
K
-
Y
A
M
G
H
G
----
G
L
R
P
E
A
A
G
A
V
V
F
-
K
V
-----------------------------------------
22
HHSearch
29.99
11%
-32
- C4 -
1YGY
1
SERA_MYCTU
A:
[331-447]
------------------------
V
-
R
K
L
G
V
L
-----------
A
G
V
L
S
--
D
----
E
-----
L
P
V
S
L
--
S
V
Q
V
R
G
E
L
A
-
A
E
E
V
E
V
L
R
---------------------
L
S
A
L
R
G
L
F
S
A
V
I
E
D
A
-
V
T
----
F
------
V
N
A
P
A
----------------
L
A
A
E
R
G
--
V
-------
T
A
E
I
C
K
A
--
S
E
S
-
P
N
H
R
S
V
----
V
D
V
R
A
V
G
A
D
G
S
-
V
V
T
V
S
-----
G
T
L
---
Y
G
P
Q
L
S
Q
----
K
I
V
Q
I
N
G
R
H
F
D
L
R
---
A
Q
G
I
N
L
I
I
H
Y
-----------------
V
D
R
P
G
A
L
G
K
I
G
T
L
L
G
T
A
G
V
N
-----
I
Q
A
A
Q
L
S
E
----
D
A
E
G
--
P
G
A
----
T
I
L
L
-
R
L
D
------------------------
Q
D
V
------------
P
D
D
-
V
R
T
A
I
-----------
A
-
A
A
V
D
A
Y
K
L
E
-------
V
V
D
L
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
29.73
15%
-19
- C4 -
1SZQ
-
PRPD_ECOLI
A:
[116-251]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
G
G
I
L
A
-
T
A
D
------
W
L
S
R
N
A
V
A
S
G
K
A
P
L
T
M
K
Q
---
V
L
T
A
M
I
K
A
H
E
I
Q
G
C
I
A
L
-
E
N
S
F
--
N
R
V
G
L
--
D
H
V
L
L
V
K
V
A
S
T
A
-
V
V
A
E
M
L
-
G
L
T
R
E
E
I
L
N
A
V
S
L
A
W
V
D
G
Q
S
L
R
T
-
Y
RHA
P
N
T
G
T
R
K
---
S
W
A
A
G
D
A
T
S
R
A
V
R
L
A
L
M
A
K
T
G
E
M
G
Y
P
S
A
L
T
A
P
V
W
G
F
Y
D
V
S
F
K
-
G
E
S
F
R
F
Q
R
P
Y
G
S
Y
V
M
-
E
N
V
L
---------------------------------------
37
Fugue
26.80
14%
1
- C3 -
1AER
1
TOXA_PSEAE
A:
[1-211]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
-----
F
L
G
---
D
G
G
D
-
V
S
----
F
S
T
R
G
T
Q
N
W
T
V
E
R
---
L
L
Q
A
H
R
Q
L
E
E
-----------------
R
G
Y
V
F
V
G
Y
H
G
T
F
L
E
A
A
Q
S
I
V
F
GGVR
A
A
I
W
R
G
F
Y
----
I
A
G
D
--
P
A
L
----
A
Y
G
Y
-
A
Q
D
------------------------
Q
E
P
------------
D
A
R
-
G
R
I
R
N
-----------
G
-
A
L
L
R
V
Y
V
P
R
-------
S
S
L
P
G
F
Y
R
T
S
L
-
T
L
A
A
P
E
A
A
G
E
V
E
-
R
L
I
G
H
P
L
P
L
R
L
D
A
I
T
G
-
P
E
E
E
G
G
R
L
E
T
I
L
G
W
P
----
L
A
E
R
T
V
V
I
P
S
A
I
P
T
D
P
R
------
N
V
G
--------
G
D
L
D
P
S
S
---
I
P
D
K
E
Q
A
I
S
A
L
P
D
Y
A
S
Q
-
P
G
K
P
P
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
24.26
33%
113
- C4 -
3HNG
-
A:
[314-349]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
R
E
G
M
R
M
----
R
A
P
E
--
Y
S
T
----
P
E
I
Y
-
Q
I
M
------------------------
L
D
C
------------
W
H
R
-
D
P
K
E
R
-----------
P
-
R
F
A
E
L
V
E
K
L
-------
G
D
L
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
23.78
16%
121
- C4 -
2KEL
-
Y56B_SIRV1
A:
[20-44]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
K
D
-----------------
L
K
T
R
L
K
V
Y
C
A
K
N
N
L
Q
L
T
Q
A
I
-----
E
E
A
I
K
E
Y
L
----
Q
K
R
N
--
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
21.45
30%
116
- C4 -
1Y6A
-
A:
[313-348]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
K
E
G
T
R
M
----
R
A
P
D
--
Y
T
T
----
P
E
M
Y
-
Q
T
M
------------------------
L
D
C
------------
W
H
G
-
E
P
S
Q
R
-----------
P
-
T
F
S
E
L
V
E
H
L
-------
G
N
L
L
Q
A
N
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
21.30
30%
122
- C4 -
3VID
-
A:
[306-341]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
K
E
G
T
R
M
----
R
A
P
D
--
Y
T
T
----
P
E
M
Y
-
Q
T
M
------------------------
L
D
C
------------
W
H
G
-
E
P
S
Q
R
-----------
P
-
T
F
S
E
L
V
E
H
L
-------
G
N
L
L
Q
A
N
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
21.18
12%
118
* C4 *
2CPG
1
COPG_STRAG
A:
[9-33]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
E
S
-----------------
V
L
E
N
L
E
K
M
A
R
E
M
G
L
S
K
S
A
M
I
-----
S
V
A
L
E
N
Y
K
----
K
G
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
21.18
30%
122
- C4 -
3VHE
-
A:
[308-343]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
K
E
G
T
R
M
----
R
A
P
D
--
Y
T
T
----
P
E
M
Y
-
Q
T
M
------------------------
L
D
C
------------
W
H
G
-
E
P
S
Q
R
-----------
P
-
T
F
S
E
L
V
E
H
L
-------
G
N
L
L
Q
A
N
A
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------