@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0487: (2015-12-15 )
MKTLVKNTIYSFLLLSVLMAEDITSGLKQLDNTYQETNQQVLKNLDEIFSTTSPSANNKIGQEDALNIKKAAIALRGDLALLKANFEANELFFISEDVIFKTYMSSPELLLTYMKINPLDQKTAEQQCGISDKVLVLYCEGKLKIEQEKQNIRERLETSLKAYQSNIGGTASLITASQTLVESLKNKNFIKGIKKLMLAHNKVFLNYLEELDALERSLEQSKRQYLQERQSSKIIVK
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.....-----------....10....-------....20........30.......---.40.....-.--------..50.........60....-------....70....-....80.........90..----......100....--.---..110.....-----..120....-----------..----.130----......---..------140---..---......150....---------....160----------------------------------.......---.170.......180....------------...190---------------------....----...200-........210--......---------.-..220.......230.....------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
K
T
L
V
-----------
K
N
T
I
Y
S
F
L
L
L
-------
S
V
L
M
A
E
D
I
T
S
G
L
K
Q
L
D
N
T
Y
Q
E
T
N
---
Q
Q
V
L
K
N
L
D
-
E
--------
I
FS-TTSPSANNKIGQ
E
D
A-------L
N
I
K
K
A
A
I
A
L-RG
D
L
A
-
L
L
KANFEA
N
E
L
F
F
----IS
E
D
V
I
F
K
T
YMS
S
--
P
---
E
L
L
L
T
Y
M
KIN-----PLDQ
K
T
A
E
Q
-----------QC----GIS-----D
K
V
L
V
L
---
Y
C------EG----
K
L
---
K
I
E
Q
E
K
Q
N
-
I
R
E
R
---------
L
E
T
S
L
K
-----------------------------------
A
Y
Q
SNIG---GT
A
S
L
I
T
A
S
Q
T
L
V
E
S
LKN------------
K
N
F
I
K
G
---------------------
I
K
K
L
----
M
L
AH
N
--
K
V
F
L
N
Y
L
E
E
----
L
D
A
L
E
R
---------
S
-
L
E
Q
S
K
R
Q
Y
L
Q
E
RQSSKIIVK------------------------------------------------------------------------------
3
PsiBlast_PDB
97.19
95%
-80
- C4 -
4YVM
-
?
A:
[8-216]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
S
G
L
K
Q
L
D
S
T
Y
K
E
T
N
---
Q
Q
V
L
K
N
L
D
-
E
--------
I
F
S
-
T
-------
K
I
G
K
E
D
A
-------
L
N
I
K
K
A
A
I
A
L
-
R
G
D
L
A
-
L
L
K
A
N
F
E
A
N
E
L
F
F
----
I
S
E
D
V
I
F
K
T
Y
M
S
S
--
P
---
E
L
L
L
T
Y
M
K
I
N
-----
P
L
D
Q
K
T
A
E
Q
-----------
Q
C
----
G
I
S
-----
D
K
V
L
V
L
---
Y
C
------
E
G
----
K
L
---
K
I
E
Q
E
K
Q
N
-
I
R
E
R
---------
L
E
T
S
L
K
-----------------------------------
A
Y
Q
S
N
I
G
---
G
T
A
S
L
I
T
A
S
Q
T
L
V
E
S
L
K
N
------------
K
N
F
I
K
G
---------------------
I
R
K
L
----
M
L
A
H
D
--
K
V
F
L
N
Y
L
E
K
----
L
D
A
L
E
I
---------
S
-
L
E
Q
S
K
R
Q
Y
L
Q
E
R
Q
S
S
-----------------------------------------------------------------------------------
4
PsiBlast_PDB
93.33
93%
-75
- C4 -
3ZCI
10
?
A:
[4-212]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
I
T
S
G
L
K
Q
L
D
S
T
Y
Q
E
T
N
---
Q
Q
V
L
K
N
L
D
-
E
--------
I
F
S
---------
E
M
G
E
E
D
A
-------
L
N
I
A
T
A
A
I
A
L
-
R
G
D
L
A
-
L
L
K
A
N
F
E
A
N
E
L
F
F
----
I
S
E
D
V
I
F
K
T
Y
M
S
S
--
P
---
E
L
L
L
T
Y
M
K
I
N
---------------------------------
S
-----
D
K
V
L
V
L
---
Y
C
------
E
G
----
K
L
---
K
I
E
A
T
A
Q
N
-
I
R
E
R
---------
L
E
T
S
L
K
-----------------------------------
A
Y
Q
S
N
I
G
---
G
T
A
S
L
I
T
A
S
Q
T
L
V
E
S
L
K
N
------------
K
N
F
I
K
G
---------------------
I
R
K
L
----
M
L
A
H
N
--
K
V
F
L
N
Y
L
E
E
----
L
D
A
L
E
R
---------
S
-
L
E
Q
S
K
R
Q
Y
L
Q
E
R
--------------------------------------------------------------------------------------
1
PsiBlast_PDB
85.49
97%
-75
- C4 -
4X5U
-
?
A:
[8-218]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
Q
L
D
S
T
Y
Q
E
T
N
---
Q
Q
V
L
K
N
L
D
-
E
--------
I
F
---------
N
E
M
G
E
E
D
A
-------
L
N
I
K
K
A
A
I
A
L
-
R
G
D
L
A
-
L
L
K
A
N
F
E
A
N
E
L
F
F
----
I
S
E
D
V
I
F
K
T
Y
M
S
S
--
P
---
E
L
L
L
T
Y
M
K
I
N
-----
P
L
D
Q
N
T
A
E
Q
-----------
Q
C
----
G
I
S
-----
D
K
V
L
V
L
---
Y
C
------
E
G
----
K
L
---
K
I
E
Q
E
K
Q
N
-
I
R
E
R
---------
L
E
T
S
L
K
-----------------------------------
A
Y
Q
S
N
I
G
---
G
T
A
S
L
I
T
A
S
Q
T
L
V
E
S
L
K
N
------------
K
N
F
I
K
G
---------------------
I
R
K
L
----
M
L
A
H
N
--
K
V
F
L
N
Y
L
E
E
----
L
D
A
L
E
R
---------
S
-
L
E
Q
S
K
R
Q
Y
L
Q
E
R
Q
S
S
K
I
I
V
K
------------------------------------------------------------------------------
2
PsiBlast_PDB
77.25
97%
-77
- C4 -
4CII
1
?
A:
[41-217]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
E
D
A
-------
L
N
I
K
K
A
A
I
A
L
-
R
G
D
L
A
-
L
L
K
A
N
F
E
A
N
E
L
F
F
----
I
S
E
D
V
I
F
K
T
Y
M
S
S
--
P
---
E
L
L
L
T
Y
M
K
I
N
-----
P
L
D
Q
N
T
A
E
Q
-----------
Q
C
----
G
I
S
-----
D
K
V
L
V
L
---
Y
C
------
E
G
----
K
L
---
K
I
E
Q
E
K
Q
N
-
I
R
E
R
---------
L
E
T
S
L
K
-----------------------------------
A
Y
Q
S
N
I
G
---
G
T
A
S
L
I
T
A
S
Q
T
L
V
E
S
L
K
N
------------
K
N
F
I
K
G
---------------------
I
R
K
L
----
M
L
A
H
N
--
K
V
F
L
N
Y
L
E
E
----
L
D
A
L
E
R
---------
S
-
L
E
Q
S
K
R
Q
Y
L
Q
E
R
Q
S
S
K
I
I
V
K
------------------------------------------------------------------------------
24
Fugue
51.45
16%
-19
- C3 -
4MFL
7
?
A:
[23-345]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MD
P
E
T
V
R
I
A
L
G
L
E
E
R
T
-----------
A
A
W
L
T
E
L
D
E
L
GPPAE
P
V
R
L
P
R
G
E
E
A
R
D
L
L
R
R
L
E
V
P
E
L
D
A
E
---
E
I
V
A
A
A
P
D
-
P
DRD
P
A
L
W
W
L
L
E
-
R
T
H
H
A
I
V
R
H
M
G
D
H
R
A
KPRGGPP
L
P
Y
E
G
G
A
A
A
R
-
Y
F
H
V
Y
-
V
F
L
A
T
V
P
A
V
R
R
F
H
A
E
R
G
I
P
D
E
V
G
W
E
T
L
T
Q
L
--
G
---
E
L
V
A
I
H
R
R
K
Y
G
Q
G
G
M
N
M
Q
W
W
T
T
Y
H
L
R
GILYRLGR
L
Q
F
----
S
L
A
TGKDG
T
P
H
L
G
L
---
A
V
P
EW---
G
G
----
P
L
L
P
K
A
Y
D
E
S
L
H
R
-
A
R
P
F
---------
F
D
R
H
F
P
-----------------------------------
E
H
G
A
R
V
A
---
W
G
S
S
W
M
L
D
P
Q
L
E
E
Y
L
T
E
D
------------
S
N
I
I
Q
L
A
R
F
WTLTDSAPEPGNADG
D
S
S
I
L
E
F
----
V
F
R
Y
N
--
G
Q
P
L
D
E
L
P
Q
----
R
S
S
L
E
R
---------
A
V
I
A
H
L
K
A
G
R
H
W
H
M
R
T
G
F
V
K
L
P
------------------------------------------------------------------------------
26
Fugue
48.11
13%
14
- C4 -
2OSZ
-
NUPL1_RAT
A:
[326-411]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
---
A
P
A
D
Y
F
R
V
-
L
V
Q
Q
---------
F
E
V
Q
L
Q
-----------------------------------
Q
Y
R
Q
Q
I
E
---
E
L
E
N
H
L
A
T
Q
A
N
N
-----
S
------------
H
I
T
P
Q
D
---------------------
L
S
M
A
----
M
Q
K
I
Y
--
Q
T
F
V
A
L
A
A
Q
----
L
Q
S
I
H
E
---------
N
-
V
K
V
L
K
E
Q
Y
L
S
Y
R
K
M
F
L
----------------------------------------------------------------------------------
21
Fugue
46.64
12%
-50
- C2 -
2A3V
-
?
A:
[2-320]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G
S
Q
F
L
L
S
V
R
E
F
M
Q
T
R
YYA
K
K
T
I
E
A
Y
L
H
W
I
T
R
Y
I
H
-----------
F
H
N
K
K
H
P
S
L
M
-------
G
D
K
E
V
E
E
F
L
T
Y
L
A
V
Q
G
K
V
A
T
K
T
Q
---
S
L
A
L
N
S
L
S
-
F
--------
L
Y
K
E
I
L
K
T
P
L
S
L
E
I
R
F
Q
R
S
-------
Q
L
E
R
K
L
P
V
V
L
T
R
D
E
I
R
-
R
L
L
E
I
V
D
P
K
H
Q
L
P
----
I
--
K
L
L
Y
G
S
G
L
R
L
--
M
---
E
C
M
--
R
L
R
V
Q
-----
D
I
D
F
D
Y
G
A
I
-----------
R
I
W
QGK
G
G
K
-----
N
R
T
V
T
L
---
A
K
------
E
L
----
Y
P
---
H
L
K
E
Q
I
A
L
-
A
K
R
Y
---------
Y
D
R
D
L
H
QKNYG
G
V
W
L
P
TA
L
K
E
K
Y
P
NAPYEFRWHYLFPSF
Q
L
S
L
D
P
E
S
D
---
V
M
R
R
H
H
M
N
E
T
V
L
Q
K
A
V
R
R
------------
S
A
Q
E
A
G
---------------------
I
E
K
T
----
V
T
C
H
T
L
R
H
S
F
A
T
H
L
L
E
V
GAD
I
R
T
V
Q
E
---------
Q
-
L
G
H
T
D
V
K
T
T
Q
I
Y
T
H
S
G
V
L
S
P
LSRL--------------------------------------------------------------------------
23
Fugue
46.59
13%
-24
* C5 *
1N2S
2
RMLD_SALTY
A:
[1-298]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
I
L
L
F
GKTG
Q
V
G
---
W
E
L
Q
R
S
L
A
P
V
-------
G
N
L
I
A
L
D
V
H
S
K
E
F
C
G
D
F
S
N
P
K
G
V
---
A
E
T
V
R
K
L
R
P
D
--------
V
I
V
-
N
A
A
A
H
T
A
V
D
K
A
E
S
E
P
-------
E
L
A
Q
L
L
N
A
T
S
-
V
E
A
I
A
-
K
A
A
N
E
T
G
A
-
W
V
V
H
----
Y
S
T
D
Y
V
F
P
G
T
G
D
I
--
P
W
Q
E
T
D
A
T
S
P
L
N
V
Y
-----
G
K
T
K
L
A
G
E
K
-----------
A
L
----
Q
D
N
C----
P
K
H
L
I
F
---
R
T
S
WVYAG
K
G
----
N
N
---
F
A
K
T
M
L
R
L
-
A
K
E
R
-----------
Q
T
L
S
-----------------------------------
V
I
N
D
Q
Y
G
A
PT
G
A
E
L
L
A
D
C
T
A
H
A
I
R
V
A
L
N
------------
K
P
E
V
A
G
---------------------
L
Y
H
L
V
A
G
G
T
T
T
W
H
--
D
Y
A
A
L
V
F
D
E
----
A
R
K
A
G
I
---------
T
-
L
A
L
T
E
L
N
A
V
P
T
S
A
Y
P
T
P
A
S
R
P
GNSRLNT
E
K
F
Q
R
N
F
D
L
I
L
P
Q
W
E
L
G
V
K
R
M
L
T
E
M
F
T
TTT----------------------------------------
25
Fugue
41.31
13%
0
- C3 -
1AZS
1
B:
[10-208]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
Q
S
Y
D
C
V
-------
C
V
M
F
A
S
I
P
D
F
K
E
F
Y
---
T
E
S
D
V
N
KEG
L
E
C
L
R
L
L
N
-
E
--------
I
I
A
-
D
F
D
D
L
L
S
----
K
P
K
F
-------
S
G
V
E
K
I
K
T
I
---
G
S
T
Y
-
M
A
A
T
G
L
S
A
I
R
--------
Q
Y
M
H
I
G
T
M
V
E
F
A
--
Y
---
A
L
V
G
K
L
D
A
I
N
-----
K
H
S
F
N
D
F
K
L
-----------
R
V
----
G
I
N
-----
H
G
P
V
I
A
---
G
V
------
I
G
AQK
P
Q
Y
---
D
I
W
G
N
T
V
N
-
V
A
S
R
---------
M
D
S
T
-----------------------------------------------
G
V
L
D
K
I
Q
V
T
E
E
T
S
L
I
L
Q
T
------------
L
G
Y
-------------------------------------------
T
C
T
C
R
----
G
---
I
I
---------
N
-
V
K
G
K
--
G
----
D
L
K
T
Y
F
V
N
T
------------------------------------------------------------------------------
29
Fugue
41.29
13%
-30
* C3 *
1GOS
1
AOFB_HUMAN
A:
[4-500]
KC
D
V
V
V
VGGG
I
S
G
M
A
A
A
K
L
L
H
D
S
GLN
V
V
V
L
E
ARDRVGGR
T
Y
T
L
R
N
QKVKYVDL
G
G
S
Y
V
GPTQNR
I
L
R
L
A
K
E
L
G
L
E
T
Y
K
V
NEV
E
R
L
I
H
H
V
KG
K
S
Y
P
F
R
G
P
F
P
P
V
W
N
PIT
Y
L
D
H
N
N
F
W
R
T
M
D
D
M
G
REIPSDAPWKAPL
A
E
E
W
D
N
MT
M
K
E
L
L
D
K
L
CWT
E
S
A
K
Q
L
A
T
L
F
V
N
L
CVTAETHEVS
A
L
W
F
L
W
Y
V
K
Q
C
GG
T
T
R
I
I
STTNGGQERKFVG
G
S
G
Q
V
-----------
S
E
R
I
M
D
L
L
G
D
-------
R
V
K
L
E
R
P
V
I
Y
I
D
Q
T
R
E
N
V
L
V
E
T
L
---
N
H
E
M
Y
E
A
K
-
Y
--------
V
I
S
-
A
I
P
P
T
L
G
M
K
I
H
F
N
P
P
-------
L
P
M
M
R
N
Q
M
I
T
-
R
V
P
L
G
S
V
I
K
C
I
V
Y
Y
K
E
P
F
W
----
R
K
K
D
Y
C
G
T
M
I
I
D
G
--
E
---
E
A
P
V
A
Y
T
L
D
D
-----
T
K
P
E
G
-----------------------
N
-----
Y
A
A
I
M
G
---
F
I
------
L
A
----
H
K
---
A
R
K
L
A
R
L
T
-
K
E
E
R
---------
L
K
K
L
C
E
-----------------------------------
L
Y
A
K
V
L
G
---
S
-
L
E
A
L
E
P
V
H
Y
E
E
K
N
W
C
E
------------
E
Q
Y
S
G
G
---------------------
C
Y
T
T
----
Y
F
P
P
G
-----------------------------------
I
L
T
Q
Y
G
R
V
L
R
Q
P
V
D
R
I
Y
F
A
G
TETATHWSGY
M
E
G
A
V
E
A
G
E
R
A
A
R
E
I
L
H
A
M
GKIPEDEI
W
Q
S
E
P
E
SVDV
P
A
Q
P
I
T
T
T
FLERHLPS
V
P
G
L
L
R
L
IGLTT
27
Fugue
41.21
11%
-16
- C5 -
2GGS
1
?
A:
[1-273]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
T
L
I
T
GASG
Q
L
G
I
E
L
S
R
L
L
S
E
R
H
E
V
-------
I
K
V
Y
N
S
S
E
I
Q
G
G
Y
K
L
D
L
T
D
F
P
R
L
---
E
D
F
I
I
K
K
R
P
D
--------
V
I
I
-
N
A
A
A
M
T
D
V
D
K
C
E
I
E
K
-------
E
K
A
Y
K
I
N
A
E
A
-
V
R
H
I
V
-
R
A
G
K
V
I
D
S
-
Y
I
V
H
----
I
S
T
D
Y
V
F
D
G
E
K
G
N
YK
E
---
E
D
I
P
N
P
I
N
Y
Y
-----
G
L
S
K
L
L
G
E
T
-----------
F
A
----
L
Q
D
-----
D
S
L
I
I
R
T
S
G
I
F
------
R
N
----
K
G
---
F
P
I
Y
V
Y
K
T
-
L
K
E
G
---------
K
T
V
F
A
F
-----------------------------------
K
G
Y
Y
S
P
I
---
S
A
R
K
L
A
S
A
I
L
E
L
L
E
L
R
K
T
G
I
I
H
V
A
G
E
RIS
R
F
E
L
A
L
K
---------------------
I
K
E
K
----
F
N
L
P
G
--
E
V
K
E
V
D
E
V
R
----
G
W
I
A
K
R
P
YDSSLDS
S
R
-
A
R
K
I
L
S
T
D
F
Y
T
L
D
L
D
G
M
V
V
-------------------------------------------------------------------------------
28
Fugue
34.25
26%
94
* C4 *
2QDQ
-
A:
[2496-2529]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
G
I
--
A
Q
I
I
A
A
Q
E
E
----
M
L
R
K
E
R
---------
E
-
L
E
E
A
R
K
K
L
A
Q
I
R
Q
Q
Q
-----------------------------------------------------------------------------------
18
HHSearch
33.42
12%
162
- C4 -
2P06
-
Y060_ARCFU
A:
[22-42]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
Y
----
F
R
L
A
E
K
---------
F
-
L
R
E
M
H
A
K
Y
M
K
R
V
S
R
P
G
N
T
P
R
------------------------------------------------------------------------------
10
HHSearch
32.93
19%
26
- C4 -
1X4Q
-
PRPF3_HUMAN
A:
[18-64]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
-----
P
W
I
E
K
T
V
K
R
-----------
V
L
----
G
F
S
-----
E
P
T
V
V
T
---
A
A
------
L
N
----
C
V
---
G
K
G
M
D
K
K
K
-
A
A
D
H
---------
L
K
P
F
L
D
-----------------------------------
D
S
T
L
R
F
V
---
D
K
L
F
E
A
V
E
E
G
R
S
S
R
H
S
S
G
------------
P
S
S
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
31.93
24%
7
- C4 -
4NSL
1
?
A:
[315-394]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
N
-----
P
I
D
F
E
N
S
E
G
-----------
N
L
----
G
L
S
-----
N
A
V
L
-
H
---
H
L
------
A
N
----
K
L
---
P
V
S
R
W
Q
R
D
-
L
T
D
S
T
V
L
R
N
LG
V
G
I
G
Y
A
L
I
-----------------------------------
A
Y
Q
S
T
L
K
---
G
V
S
K
L
E
V
N
R
D
H
L
L
D
E
L
D
H
------------
N
W
E
V
L
A
---------------------
E
P
I
Q
----
T
V
M
R
R
--
Y
G
I
E
K
P
Y
E
K
----
L
K
E
L
T
R
---------
K
-
R
V
D
A
E
G
M
K
Q
F
I
D
S
L
A
L
P
E
A
E
------------------------------------------------------------------------------
8
PsiBlast_PDB
31.85
24%
18
- C4 -
3GZH
3
?
A:
[327-406]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
N
-----
P
I
D
F
E
N
S
E
G
-----------
N
L
----
G
L
S
-----
N
A
V
L
-
Q
---
H
L
------
A
S
----
K
L
---
P
V
S
R
W
Q
R
D
-
L
T
D
S
T
V
L
R
N
L
G
V
G
I
G
Y
A
L
I
-----------------------------------
A
Y
Q
S
T
L
K
---
G
V
S
K
L
E
V
N
R
D
H
L
L
D
E
L
D
H
------------
N
W
E
V
L
A
---------------------
E
P
I
Q
----
T
V
M
R
R
--
Y
G
I
E
K
P
Y
E
K
----
L
K
E
L
T
R
---------
G
-
K
R
V
D
A
E
G
M
K
Q
F
I
D
G
L
A
L
P
E
E
------------------------------------------------------------------------------
9
PsiBlast_PDB
31.52
24%
16
- C4 -
2PTS
-
PUR8_ECOLI
A:
[301-380]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
N
-----
P
I
D
F
E
N
S
E
G
-----------
N
L
----
G
L
S
-----
N
A
V
L
-
Q
---
H
L
------
A
S
----
K
L
---
P
V
S
R
W
Q
R
D
-
L
T
D
S
T
V
L
R
N
L
G
V
G
I
G
Y
A
L
I
-----------------------------------
A
Y
Q
S
T
L
K
---
G
V
S
K
L
E
V
N
R
D
H
L
L
D
E
L
D
H
------------
N
W
E
V
L
A
---------------------
E
P
I
Q
----
T
V
M
R
R
--
Y
G
I
E
K
P
Y
E
K
----
L
K
E
L
T
R
---------
V
-
D
A
E
G
M
K
Q
F
I
D
G
L
A
L
P
E
E
E
K
A
------------------------------------------------------------------------------
12
HHSearch
31.28
19%
23
- C4 -
1MP1
-
SRRM1_HUMAN
A:
[46-94]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
I
K
-----
P
W
I
T
K
R
V
T
E
-----------
I
L
----
G
F
E
-----
D
D
V
V
I
E
---
F
I
------
F
N
----
Q
L
---
E
V
K
N
P
D
S
K
M
M
Q
I
N
---------
L
T
G
F
L
N
-----------------------------------
G
K
N
A
R
E
F
---
M
G
E
L
W
P
L
L
L
S
A
Q
E
N
I
A
G
I
------------
P
S
A
F
L
E
---------------------
L
K
K
E
----
E
I
K
Q
R
----------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
31.22
24%
14
- C4 -
2PTQ
3
PUR8_ECOLI
A:
[301-380]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
N
-----
P
I
D
F
E
N
S
E
G
-----------
N
L
----
G
L
S
-----
N
A
V
L
-
Q
---
H
L
------
A
S
----
K
L
---
P
V
S
R
W
Q
R
D
-
L
T
D
S
T
V
L
R
N
L
G
V
G
I
G
Y
A
L
I
-----------------------------------
A
Y
Q
S
T
L
K
---
G
V
S
K
L
E
V
N
R
D
H
L
L
D
E
L
D
H
------------
N
W
E
V
L
A
---------------------
E
P
I
Q
----
T
V
M
R
R
--
Y
G
I
E
K
P
Y
E
K
----
L
K
E
L
T
R
---------
G
-
K
R
V
D
A
E
G
M
K
Q
F
I
D
G
L
A
L
P
E
E
------------------------------------------------------------------------------
7
PsiBlast_PDB
30.35
24%
14
- C4 -
2PTR
1
PUR8_ECOLI
A:
[301-380]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
N
-----
P
I
D
F
E
N
S
E
G
-----------
N
L
----
G
L
S
-----
N
A
V
L
-
Q
---
H
L
------
A
S
----
K
L
---
P
V
S
R
W
Q
R
D
-
L
T
D
S
T
V
L
R
N
L
G
V
G
I
G
Y
A
L
I
-----------------------------------
A
Y
Q
S
T
L
K
---
G
V
S
K
L
E
V
N
R
D
H
L
L
D
E
L
D
H
------------
N
W
E
V
L
A
---------------------
E
P
I
Q
----
T
V
M
R
R
--
Y
G
I
E
K
P
Y
E
K
----
L
K
E
L
V
D
---------
A
-
E
G
M
K
Q
F
I
D
G
L
A
L
P
E
E
E
K
A
R
L
------------------------------------------------------------------------------