@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_0711: (2015-12-17 )
MEQKISVALKEIKRGANEIIGLEYIEKLVRKYYETNERFIVKAGFDPTAPDLHLGHTVLIQKLALLQQYGARVKFLIGDFTAMIGDPTGKNETRKPLNREQVLENAKTYKEQIYKILDQKHTEVCFNSAWLDALGAKGMIELCAKFSVARMLERDDFAKRYKENRPISIVEFLYPLLQGYDSVAMGADIELGGNDQKFNLLVGRFLQRAYGLNKEQSIITMPLLEGLDGVQKMSKSLGNYVGITEEPNAMFGKIMSVSDDLMWRYYTLLSAKTLEEIEDLKHGILHQTLHPKAVKEDLASEIVARYYDNDQAFKAKEQFSKVFSANLLPEILLESDFDEGVGVLDVLKQIGFCPSTSQARRDIQGGGVKINQEVVKDESYRFVKGNYVIQLGKKRFMKLNIN
Atome Classification :
(20 SA)
.........10........20...-..----...30........40........50........60........70........80........90........-100.......110----.--....----.----.----------120--.----......130.......140..-.-.----...150.......160........170.......180---....----....190.......200.-......210......-.220.......230......-.240...---.---...250.......-260-..--.......270.......280-----.........290.......300.......----------------310--.......----.320....----.-------------------.----------------------------.---330------....-....------.340.----------........350.......360.......370.......380---..---..--..-.-..390.......400-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
ME
Q
K
I
S
V
A
L
K
E
I
K
R
G
A
N
EII
G
L
E
Y
-
I
E
----
K
L
V
R
K
Y
YETNE
R
F
I
V
K
AGFDPTAPDLHL
G
H
T
V
L
I
Q
K
L
A
L
L
Q
QYG
A
R
V
K
F
L
IGD
F
T
A
MIGDPTGKNETRKPL
N
R
-
E
Q
V
L
E
N
A
K
T
Y
K
E
Q
----
I
--
Y
K
I
L
----
D
----
Q
----------
K
H
T
--
E
----
V
C
F
N
S
A
W
L
D
A
LGAK
G
M
I
E
L
C
A
-
K
-
F
----
S
V
A
R
M
L
E
R
D
D
F
A
K
R
Y
-KENRPI
S
I
V
E
F
L
Y
P
L
L
QGYD----SVAM----G
A
D
I
E
LGGND
Q
K
F
N
L
L
V
G
-
R
F
L
Q
R
A
YGLNKEQ
S
I
-
I
T
M
P
L
L
E
G
L
D
G
V
Q
K
M
S
K
SLG-NYVGITE---E---
P
N
A
M
F
G
K
I
M
SVS
D
-
D
---
L
M
--
W
R
Y
Y
T
L
L
S
A
K
T
L
E
E
I
E
D
L
-------
K
H
G
I
L
HQTL
H
P
K
A
V
K
E
D
L
A
S
E
I
V
A
R
YYDN----------------
D
Q
---
A
F
K
A
K
E
Q
----
F
S
K
V
F
S
A
N
----
L
-------------------
L
----------------------------
P
---
E
--------
I
L
L
E-SDFD------EG--V----------
G
V
L
D
V
L
K
QIGFCPS
T
S
Q
A
R
RDIQGG
G
V
K
I
N
Q
E
VVKDES
Y
-----
R
F
---VK--G
N
-
Y
-
V
I
Q
LGK
K
R
F
M
K
LNIN-
21
PsiBlast_CBE
97.18
41%
-97
- C3 -
1H3F
4
SYY_THET2
B:
[11-431]
-------
A
L
A
L
L
K
R
G
A
E
E
I
V
P
----
E
E
----
E
L
L
A
K
L
K
E
G
R
P
-
L
T
V
K
L
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A
D
P
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L
H
L
G
H
A
V
V
L
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K
M
R
Q
F
Q
E
L
G
H
K
V
V
L
I
I
G
D
F
T
G
M
I
-------------
T
L
-
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E
T
R
E
N
A
K
T
Y
V
A
Q
----
A
--
G
K
I
L
----
R
----
Q
----------
E
P
H
L
F
E
----
L
R
Y
N
S
E
W
L
E
G
L
T
F
K
E
V
V
R
L
T
S
-
L
-
M
----
T
V
A
Q
M
L
E
R
E
D
F
K
K
R
Y
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A
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A
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V
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G
G
T
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F
N
L
L
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R
E
V
Q
R
A
Y
G
-
Q
S
P
Q
V
C
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L
L
V
G
L
D
G
R
E
K
M
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K
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L
D
-
N
Y
I
G
L
T
E
---
P
---
P
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A
M
F
K
K
L
M
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P
D
-
P
---
L
L
--
P
S
Y
F
R
L
L
T
D
L
E
E
E
E
I
E
A
L
L
K
A
G
P
V
P
A
H
R
V
L
A
R
L
L
T
A
A
Y
A
L
P
Q
I
P
P
R
I
D
R
A
F
Y
E
S
L
GYAWEAFGRDKEAGP
E
E
---
V
R
R
A
E
A
R
----
Y
D
-----------E------------------
I
----------------------------
P
---
E
--------
V
T
I
P
A
S
E
L
K
------
E
G
R
-
I
----------
W
V
A
R
L
F
T
L
A
G
L
T
P
S
N
A
E
A
R
R
L
I
Q
N
R
G
L
R
L
D
G
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V
L
T
D
P
M
L
-----
Q
V
D
--
L
S
--
R
P
-
R
-
I
L
Q
R
G
K
D
R
F
V
R
V
R
L
S
-
2
PsiBlast_PDB
95.46
41%
-85
- C3 -
1H3E
2
SYY_THET2
A:
[11-431]
-------
A
L
A
L
L
K
R
G
A
E
E
I
V
P
----
E
E
----
E
L
L
A
K
L
K
E
G
R
P
-
L
T
V
K
L
G
A
D
P
T
R
P
D
L
H
L
G
H
A
V
V
L
R
K
M
R
Q
F
Q
E
L
G
H
K
V
V
L
I
I
G
D
F
T
G
M
I
G
D
P
S
G
R
S
K
T
R
P
P
L
T
L
-
E
E
T
R
E
N
A
K
T
Y
V
A
Q
----
A
--
G
K
I
L
----
R
----
Q
----------
E
P
H
L
F
E
----
L
R
Y
N
S
E
W
L
E
G
L
T
F
K
E
V
V
R
L
T
S
-
L
-
M
----
T
V
A
Q
M
L
E
R
E
D
F
K
K
R
Y
-
E
A
G
I
P
I
S
L
H
E
L
L
Y
P
F
A
Q
A
Y
D
----
S
V
A
I
----
R
A
D
V
E
M
G
G
T
D
Q
R
F
N
L
L
V
G
-
R
E
V
Q
R
A
Y
G
-
Q
S
P
Q
V
C
-
F
L
M
P
L
L
V
G
L
D
G
R
E
K
M
S
K
S
L
D
-
N
Y
I
G
L
T
E
---
P
---
P
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A
M
F
K
K
L
M
R
V
P
D
-
P
---
L
L
--
P
S
Y
F
R
L
L
T
D
L
E
E
E
E
I
E
A
L
L
K
A
G
P
V
P
A
H
R
V
L
A
R
L
L
T
A
A
Y
A
L
P
Q
I
P
P
R
I
D
R
A
F
Y
E
S
L
GYAWEAFGRDKEAGP
E
E
---
V
R
R
A
E
A
R
----
Y
D
E
V
A
K
G
G
----
I
PE
E
----------------
I
----------------------------
P
---
E
--------
V
T
I
P
A
S
E
L
K
------
E
G
R-
I
----------
W
V
A
R
L
F
T
L
A
G
L
T
P
S
N
A
E
A
R
R
L
I
Q
N
R
G
L
R
L
D
G
E
V
L
T
D
P
M
L
-----
Q
V
D
--
L
S
--
R
P
-
R
-
I
L
Q
R
G
K
D
R
F
V
R
V
R
L
S
-
1
PsiBlast_PDB
94.90
41%
-93
- C3 -
1H3F
3
SYY_THET2
A:
[11-431]
-------
A
L
A
L
L
K
R
G
A
E
E
I
V
P
----
E
E
----
E
L
L
A
K
L
K
E
G
R
P
-
L
T
V
K
L
G
A
D
P
T
R
P
D
L
H
L
G
H
A
V
V
L
R
K
M
R
Q
F
Q
E
L
G
H
K
V
V
L
I
I
G
D
F
T
----------------------
R
E
N
A
K
T
Y
V
A
Q
----
A
--
G
K
I
L
----
R
----
Q
----------
E
P
H
L
F
E
----
L
R
Y
N
S
E
W
L
E
G
L
T
F
K
E
V
V
R
L
T
S
-
L
-
M
----
T
V
A
Q
M
L
E
R
E
D
F
K
K
R
Y
-
E
A
G
I
P
I
S
L
H
E
L
L
Y
P
F
A
Q
A
Y
D
----
S
V
A
I
----
R
A
D
V
E
M
G
G
T
D
Q
R
F
N
L
L
V
G
-
R
E
V
Q
R
A
Y
G
-
Q
S
P
Q
V
C
-
F
L
M
P
L
L
V
G
L
D
G
R
E
K
M
S
K
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L
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-
N
Y
I
G
L
T
E
---
P
---
P
E
A
M
F
K
K
L
M
R
V
P
D
-
P
---
L
L
--
P
S
Y
F
R
L
L
T
D
L
E
E
E
E
I
E
A
L
L
K
A
G
P
V
P
A
H
R
V
L
A
R
L
L
T
A
A
Y
A
L
P
Q
I
P
P
R
I
D
R
A
F
Y
E
S
L
GYAWEAFGRDKEAGP
E
E
---
V
R
R
A
E
A
R
----
Y
D
E
V
A
K
-------EE-----------------
I
----------------------------
P
---
E
--------
V
T
I
P
A
S
E
L
K
------
E
G
R-
I
----------
W
V
A
R
L
F
T
L
A
G
L
T
P
S
N
A
E
A
R
R
L
I
Q
N
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R
L
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G
E
V
L
T
D
P
M
L
-----
Q
V
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--
L
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R
P
-
R
-
I
L
Q
R
G
K
D
R
F
V
R
V
R
L
S
-
56
Fugue
93.38
42%
-87
- C3 -
1H3F
3
SYY_THET2
A:
[5-432]
-
G
H
T
P
E
E
A
L
A
L
L
K
R
G
A
E
E
I
V
P
-----
E
----
E
E
L
L
A
K
L
K
E
G
R
P
L
T
V
K
L
G
A
D
P
T
R
P
D
L
H
L
G
H
A
V
V
L
R
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M
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Q
F
Q
E
L
G
H
K
V
V
L
I
I
G
D
F
T
----------------------
R
E
N
A
K
T
Y
V
A
Q
----
A
--
G
K
I
L
R
Q
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E
----
P
----------
H
L
F
--
E
----
L
R
Y
N
S
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W
L
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G
L
T
F
K
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V
V
R
L
T
S
-
L
-
M
----
T
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F
K
K
R
Y
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A
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A
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A
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G
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P
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L
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D
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A
L
-------
L
K
A
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G
P
V
P
A
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R
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A
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L
L
T
A
A
Y
A
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Q
I
---
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P
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A
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Y
A
----
W
-------------------
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AFGRDKEAGP
E
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AKEEI
P
---
E
--------
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------
K
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GR
I
----------
W
V
A
R
L
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T
L
A
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L
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P
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N
A
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A
R
R
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L
R
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M
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-----
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V
---
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L
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P
R
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L
Q
R
G
K
D
R
F
V
R
V
R
L
S
D
38
HHSearch
91.93
42%
-88
- C3 -
1H3F
3
SYY_THET2
A:
[5-431]
-
G
H
T
P
E
E
A
L
A
L
L
K
R
G
A
E
E
I
V
P
E
E
E
-
L
L
----
A
K
L
K
----
E
G
R
P
L
T
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G
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V
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Q
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K
V
V
L
I
I
G
D
F
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----------------------
R
E
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A
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Y
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A
Q
----
A
G
K
I
L
R
Q
----
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----
P
----------
H
L
F
--
E
----
L
R
Y
N
S
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W
L
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L
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K
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V
R
-
L
T
S
L
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M
----
T
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A
Q
M
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F
K
K
R
Y
-
E
A
G
I
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I
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L
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L
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F
A
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A
Y
D
----
S
V
A
I
----
R
A
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G
G
T
D
Q
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F
N
L
L
V
G
-
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R
A
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Q
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P
Q
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C
-
F
L
M
P
L
L
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D
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L
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-
P
---
L
L
--
P
S
Y
F
R
L
L
T
D
L
E
E
E
E
I
E
A
L
-------
L
K
A
G
------
P
V
P
A
H
R
V
L
A
R
L
L
T
A
A
Y
A
L
P
----------------
Q
I
PPR
I
D
R
A
F
Y
E
S
L
GY
A
W
E
A
F
G
R
D
----
K
EAGP
E
E
V
R
R
A
E
A
R
Y
D
E
V
AK---------------------------------
E
--------
E
I
P
E
-
V
T
I
P
ASELKE
G
R
--
I
----------
W
V
A
R
L
F
T
L
A
G
L
T
P
S
N
A
E
A
R
R
L
I
Q
N
R
G
L
R
L
D
G
E
V
L
T
D
P
M
L
-----
Q
V
---
D
L
--
S
R
P
R
-
I
L
Q
R
G
K
D
R
F
V
R
V
R
L
S
-
9
PsiBlast_PDB
84.57
30%
-82
- C3 -
2JAN
-
SYY_MYCTU
A:
[33-415]
-------------------------------------------
M
T
V
Y
A
G
F
D
P
T
A
P
S
L
H
A
G
H
L
V
P
L
L
T
L
R
R
F
Q
R
A
G
H
R
P
I
V
L
A
G
G
A
T
G
M
I
G
D
P
R
D
V
G
E
--
R
S
L
N
E
A
D
T
V
A
E
W
T
E
R
I
R
G
Q
----
L
--
E
R
F
V
----
D
----
F
----------
D
D
S
--
P
M
G
A
I
V
E
N
N
L
E
W
T
G
S
L
S
A
I
E
F
L
R
D
I
G
-
K
H
F
----
S
V
N
V
M
L
A
R
D
T
I
R
R
R
L
-
A
-
G
E
G
I
S
Y
T
E
F
S
Y
L
L
L
Q
A
N
D
----
Y
V
E
L
H
R
R
H
G
C
T
L
Q
I
G
G
A
D
Q
W
G
N
I
I
A
G
-
V
R
L
V
R
Q
K
-
L
G
A
T
V
H
A
-
L
T
V
P
L
V
T
A
A
D
G
T
K
F
G
K
S
T
G
G
-
G
S
L
W
L
D
P
---
Q
MTS
P
Y
A
W
Y
Q
Y
F
V
N
T
A
D
A
D
---
V
I
R
Y
L
R
W
F
T
F
L
S
A
D
E
L
A
E
L
E
Q
A
-------
T
----
A
Q
R
P
Q
Q
R
A
A
Q
R
R
L
A
S
E
L
T
V
L
V
H
-
G
----------------
E
A
---
A
T
A
A
V
E
H
----
A
S
R
A
L
F
G
R
GELA
R
-------------------
L
----------------------------
D
---
E
--------
A
T
L
A
-
A
A
L
R
------
E
T
--
T
V
A
E
L
K
P
GSPD
G
I
V
D
L
L
V
A
S
G
L
S
A
S
K
G
A
A
R
R
T
I
H
E
G
G
V
S
V
N
N
I
R
V
D
N
E
E
W
V
P
Q
SS
D
F
---
L
H
--
G
R
-
W
L
V
L
R
R
G
K
R
S
I
A
G
V
E
R
I
-
37
HHSearch
81.33
28%
-78
- C3 -
2JAN
-
SYY_MYCTU
A:
[5-422]
------
I
L
D
E
L
S
W
R
G
L
I
A
Q
S
T
D
L
D
T
L
A
----
A
E
A
Q
-----
R
G
P
M
T
V
Y
A
G
F
D
P
T
A
P
S
L
H
A
G
H
L
V
P
L
L
T
L
R
R
F
Q
R
A
G
H
R
P
I
V
L
A
G
G
A
T
G
M
I
G
D
P
R
D
-
V
G
E
R
S
L
N
E
A
-
D
T
V
A
E
W
T
E
R
I
R
G
Q
L
E
R
F
V
--
D
F
D
D
----
S
----
P
----------
M
G
A
--
I
----
V
E
N
N
L
E
W
T
G
S
L
S
A
I
E
F
L
R
D
I
G
K
H
-
F
----
S
V
N
V
M
L
A
R
D
T
I
R
R
R
L
-
A
-
G
E
G
I
S
Y
T
E
F
S
Y
L
L
L
Q
A
N
D
----
Y
V
E
L
H
R
R
H
G
C
T
L
Q
I
G
G
A
D
Q
W
G
N
I
I
A
G
-
V
R
L
V
R
Q
K
L
G
A
-
T
V
H
A
-
L
T
V
P
L
V
T
A
A
D
G
-
T
K
F
G
K
S
T
G
G
G
S
L
W
L
D
P
QMT
S
---
P
Y
A
W
Y
Q
Y
F
V
N
T
A
D
-
A
---
D
V
--
I
R
Y
L
R
W
F
T
F
L
S
A
D
E
L
A
E
L
-------
E
Q
A
T
A
-
Q
R
P
Q
Q
R
A
A
Q
R
R
L
A
S
E
L
T
V
L
V
H
G
E
----------------
A
A
---
T
A
A
V
E
H
A
----
S
R
A
L
F
G
R
G
----
E
-------------------
L
----------------------------
A
RLD
E
A
T
L
A
A
A
L
R
E
T
T
V
-
A
E
L
K
P
G----
S
P
--
D
----------
G
I
V
D
L
L
V
A
S
G
L
S
A
S
K
G
A
A
R
R
T
I
H
E
G
G
V
S
V
N
N
I
R
V
D
N
E
E
W
-----
V
P
Q
SS
D
F
LH
G
R
W
L
-
V
L
R
R
G
K
R
S
I
A
G
V
E
R
I
-
7
PsiBlast_PDB
72.44
28%
-69
- C3 -
2TS1
-
SYY_GEOSE
A:
[29-319]
-----------------------------------------
E
R
V
T
L
Y
C
G
F
D
P
T
A
D
S
L
H
I
G
H
L
A
T
I
L
T
M
R
R
F
Q
Q
A
G
H
R
P
I
A
L
V
G
G
A
T
G
L
I
G
D
P
S
G
K
K
S
E
R
T
L
N
A
K
-
E
T
V
E
A
W
S
A
R
I
K
E
Q
----
L
--
G
R
F
L
DFEA
D
----
G
----------
N
P
A
--
K
----
I
K
N
N
Y
D
W
I
G
P
L
D
V
I
T
F
L
R
D
V
G
-
K
H
F
----
S
V
N
Y
M
M
A
K
E
S
V
Q
S
R
I
-
E
T
G
--
I
S
F
T
E
F
S
Y
M
M
L
Q
A
Y
D
----
F
L
R
L
Y
E
TE
G
C
R
L
Q
I
G
G
S
D
Q
W
G
N
I
T
A
G
-
L
E
L
I
R
K
T
K
G
--
R
A
F
G
-
L
T
I
P
L
V
T
K
A
D
G
T
-
K
F
G
K
T
E
S
-
G
T
I
W
L
D
K
---
E
KTS
P
Y
E
F
Y
Q
F
W
I
N
T
D
D
-
R
---
D
V
--
I
R
Y
L
K
Y
F
T
F
L
S
K
E
E
I
E
A
L
-------
E
Q
E
-
L
R
E
A
P
E
K
R
A
A
Q
K
T
L
A
E
E
V
T
K
L
V
H
G
E
----------------
E
A
---
L
R
Q
A
I
R
I
----
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
71.98
28%
-68
- C3 -
3TS1
1
SYY_GEOSE
A:
[29-319]
-----------------------------------------
E
R
V
T
L
Y
C
G
F
D
P
T
A
D
S
L
H
I
G
H
L
A
T
I
L
T
M
R
R
F
Q
Q
A
G
H
R
P
I
A
L
V
G
G
A
T
G
L
I
G
D
P
S
G
K
K
S
E
R
T
L
N
A
K
-
E
T
V
E
A
W
S
A
R
I
K
E
Q
----
L
--
G
R
F
L
DFEA
D
----
G
----------
N
P
A
--
K
----
I
K
N
N
Y
D
W
I
G
P
L
D
V
I
T
F
L
R
D
V
G
-
K
H
F
----
S
V
N
Y
M
M
A
K
E
S
V
Q
S
R
I
-
E
T
G
--
I
S
F
T
E
F
S
Y
M
M
L
Q
A
Y
D
----
F
L
R
L
Y
E
T
E
G
C
R
L
Q
I
G
G
S
D
Q
W
G
N
I
T
A
G
-
L
E
L
I
R
K
T
K
G
--
R
A
F
G
-
L
T
I
P
L
V
T
K
A
D
G
T
-
K
F
G
K
T
E
S
-
G
T
I
W
L
D
K
---
E
KTS
P
Y
E
F
Y
Q
F
W
I
N
T
D
D
-
R
---
D
V
--
I
R
Y
L
K
Y
F
T
F
L
S
K
E
E
I
E
A
L
-------
E
Q
E
-
L
R
E
A
P
E
K
R
A
A
Q
K
T
L
A
E
E
V
T
K
L
V
H
G
E
----------------
E
A
---
L
R
Q
A
I
R
I
----
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
71.90
28%
-57
- C3 -
2TS1
-
SYY_GEOSE
A:
[2-319]
-----
D
L
L
A
E
L
Q
W
R
G
L
V
N
Q
T
T
D
E
D
G
L
R
----
K
L
L
N
-----
E
E
R
V
T
L
Y
C
G
F
D
P
T
A
D
S
L
H
I
G
H
L
A
T
I
L
T
M
R
R
F
Q
Q
A
G
H
R
P
I
A
L
V
G
G
A
T
G
L
I
G
D
P
S
G
K
K
S
E
R
T
L
N
A
K
-
E
T
V
E
A
W
S
A
R
I
K
E
Q
L
G
R
F
L
--
D
F
E
A
----
D
----
G
----------
N
P
A
--
K
----
I
K
N
N
Y
D
W
I
G
P
L
D
V
I
T
F
L
R
D
V
G
K
H
-
F
----
S
V
N
Y
M
M
A
K
E
S
V
Q
S
R
I
-
E
--
T
G
I
S
F
T
E
F
S
Y
M
M
L
Q
A
Y
D
----
F
L
R
L
Y
E
TE
G
C
R
L
Q
I
G
G
S
D
Q
W
G
N
I
T
A
G
-
L
E
L
I
R
K
T
K
G
--
R
A
F
G
-
L
T
I
P
L
V
T
K
A
D
G
-
T
K
F
G
K
T
E
S
-
G
T
I
W
L
D
K
EKT
S
---
P
Y
E
F
Y
Q
F
W
I
N
T
D
D
-
R
---
D
V
--
I
R
Y
L
K
Y
F
T
F
L
S
K
E
E
I
E
A
L
-------
E
Q
E
L
R
E
-
A
P
E
K
R
A
A
Q
K
T
L
A
E
E
V
T
K
L
V
H
G
E
----------------
E
A
---
L
R
Q
A
I
R
I
----
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
70.36
29%
-71
- C3 -
1TYA
1
SYY_GEOSE
E:
[29-303]
-----------------------------------------
E
R
V
T
L
Y
C
G
F
D
P
T
A
D
S
L
H
I
G
H
L
A
A
I
L
T
M
R
R
F
Q
Q
A
G
H
R
P
I
A
L
V
G
G
A
T
G
L
I
G
D
P
S
G
K
K
S
E
R
T
L
N
A
K
-
E
T
V
E
A
W
S
A
R
I
K
E
Q
----
L
--
G
R
F
L
DFEA
D
----
G
----------
N
P
A
--
K
----
I
K
N
N
Y
D
W
I
G
P
L
D
V
I
T
F
L
R
D
V
G
-
K
H
F
----
S
V
N
Y
M
M
A
K
E
S
V
Q
S
R
I
-
E
T
G
--
I
S
F
T
E
F
S
Y
M
M
L
Q
A
Y
D
----
F
L
R
L
YETE
G
C
R
L
Q
I
G
G
S
D
Q
W
G
N
I
T
A
G
-
L
E
L
I
R
K
T
K
G
--
R
A
F
G
-
L
T
I
P
L
V
T
K
A
D
G
T
-
K
F
G
K
T
E
S
-
G
T
I
W
L
D
K
---
E
KTS
P
Y
E
F
Y
Q
F
W
I
N
T
D
D
-
R
---
D
V
--
I
R
Y
L
K
Y
F
T
F
L
S
K
E
E
I
E
A
L
-------
E
Q
E
-
L
R
E
A
P
E
K
R
A
A
Q
K
T
L
A
E
E
V
T
K
L
V
H
G
E
----------------
E
A
---
L
R
Q
A
I
R
I
----
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
70.33
26%
-57
- C3 -
2PID
1
SYYM_HUMAN
A:
[10-346]
-----
G
L
L
A
A
Q
K
A
R
G
L
F
K
D
F
F
P
E
T
G
T
K
IELP
E
L
F
--------
P
Q
T
I
Y
C
G
F
D
P
T
A
D
S
L
H
V
G
H
L
L
A
L
L
G
L
F
H
L
Q
R
A
G
H
N
V
I
A
L
V
G
G
A
T
A
R
L
G
D
P
S
G
R
T
K
E
R
E
A
L
E
T
-
E
R
V
R
A
N
A
R
A
L
R
L
G
----
L
E
-
A
L
A
A
----
N
----
H
Q
Q
LFTDGRSW
G
S
F
--
T
----
V
L
D
N
S
A
W
Y
Q
K
Q
H
L
V
D
F
L
A
A
V
G
G
H
-
F
----
R
M
G
T
L
L
S
R
Q
S
V
Q
L
R
L
-
K
S
P
E
G
M
S
L
A
E
F
F
Y
Q
V
L
Q
A
Y
D
----
F
Y
Y
L
F
Q
R
Y
G
C
R
V
Q
L
G
G
S
D
Q
L
G
N
I
M
S
G
-
Y
E
F
I
N
K
L
T
G
E
-
D
V
F
G
-
I
T
V
P
L
I
T
---------------
A
V
W
L
N
R
DKT
S
---
P
F
E
L
Y
Q
F
F
V
R
Q
P
D
-
D
---
S
V
--
E
R
Y
L
K
L
F
T
F
L
P
L
P
E
I
D
H
I
-------
M
Q
L
H
V
-
K
E
P
E
R
R
G
P
Q
K
R
L
A
A
E
V
T
K
L
V
H
G
R
----------------
E
G
---
L
D
S
A
K
R
C
----
T
Q
A
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
69.95
29%
-73
- C3 -
1TYC
-
SYY_GEOSE
A:
[29-303]
-----------------------------------------
E
R
V
T
L
Y
C
G
F
D
P
T
A
D
S
L
H
I
G
H
L
A
P
I
L
T
M
R
R
F
Q
Q
A
G
H
R
P
I
A
L
V
G
G
A
T
G
L
I
G
D
P
S
G
K
K
S
E
R
T
L
N
A
K
-
E
T
V
E
A
W
S
A
R
I
K
E
Q
----
L
--
G
R
F
L
DFEA
D
----
G
----------
N
P
A
--
K
----
I
K
N
N
Y
D
W
I
G
P
L
D
V
I
T
F
L
R
D
V
G
-
K
H
F
----
S
V
N
Y
M
M
A
K
E
S
V
Q
S
R
I
-
E
T
G
--
I
S
F
T
E
F
S
Y
M
M
L
Q
A
Y
D
----
F
L
R
L
Y
E
TE
G
C
R
L
Q
I
G
G
S
D
Q
W
G
N
I
T
A
G
-
L
E
L
I
R
K
T
K
G
--
R
A
F
G
-
L
T
I
P
L
V
T
K
A
D
G
T
-
K
F
G
K
T
E
S
-
G
T
I
W
L
D
K
---
E
KTS
P
Y
E
F
Y
Q
F
W
I
N
T
D
D
-
R
---
D
V
--
I
R
Y
L
K
Y
F
T
F
L
S
K
E
E
I
E
A
L
-------
E
Q
E
-
L
R
E
A
P
E
K
R
A
A
Q
K
T
L
A
E
E
V
T
K
L
V
H
G
E
----------------
E
A
---
L
R
Q
A
I
R
I
----
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
69.88
29%
-73
- C3 -
1TYD
1
SYY_GEOSE
E:
[29-303]
-----------------------------------------
E
R
V
T
L
Y
C
G
F
D
P
T
A
D
S
L
H
I
G
H
L
A
S
I
L
T
M
R
R
F
Q
Q
A
G
H
R
P
I
A
L
V
G
G
A
T
G
L
I
G
D
P
S
G
K
K
S
E
R
T
L
N
A
K
-
E
T
V
E
A
W
S
A
R
I
K
E
Q
----
L
--
G
R
F
L
DFEA
D
----
G
----------
N
P
A
--
K
----
I
K
N
N
Y
D
W
I
G
P
L
D
V
I
T
F
L
R
D
V
G
-
K
H
F
----
S
V
N
Y
M
M
A
K
E
S
V
Q
S
R
I
-
E
T
G
--
I
S
F
T
E
F
S
Y
M
M
L
Q
A
Y
D
----
F
L
R
L
YETE
G
C
R
L
Q
I
G
G
S
D
Q
W
G
N
I
T
A
G
-
L
E
L
I
R
K
T
K
G
--
R
A
F
G
-
L
T
I
P
L
V
T
K
A
D
G
T
-
K
F
G
K
T
E
S
-
G
T
I
W
L
D
K
---
E
KTS
P
Y
E
F
Y
Q
F
W
I
N
T
D
D
-
R
---
D
V
--
I
R
Y
L
K
Y
F
T
F
L
S
K
E
E
I
E
A
L
-------
E
Q
E
-
L
R
E
A
P
E
K
R
A
A
Q
K
T
L
A
E
E
V
T
K
L
V
H
G
E
----------------
E
A
---
L
R
Q
A
I
R
I
----
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
69.65
29%
-65
- C3 -
1VBN
1
SYY_ECOLI
A:
[34-318]
-----------------------------------------------
C
G
F
D
P
T
A
D
S
L
H
L
G
H
L
V
P
L
L
C
L
K
R
F
Q
Q
A
G
H
K
P
V
A
L
V
G
G
A
T
G
L
I
G
D
P
S
F
K
A
A
E
R
K
L
N
T
E
-
E
T
V
Q
E
W
V
D
K
I
R
K
Q
----
V
--
A
P
F
L
----
D
FDCG
E
----------
N
S
A
--
I
----
A
A
N
N
Y
D
W
F
G
N
M
N
V
L
T
F
L
R
D
I
G
-
K
H
F
----
S
V
N
Q
M
I
N
K
E
A
V
K
Q
R
L
N
R
E
D
Q
G
I
S
F
T
E
F
S
Y
N
L
L
Q
G
Y
D
----
F
A
C
L
N
K
Q
Y
G
V
V
L
C
I
G
G
S
D
Q
W
G
N
I
T
S
G
-
I
D
L
T
R
R
--
L
H
Q
N
Q
V
F
G
L
T
V
P
L
I
T
K
A
D
G
T
-
K
F
G
K
T
E
G
-
G
A
V
W
L
D
P
---
K
KTS
P
Y
K
F
Y
Q
F
W
I
N
T
A
D
-
A
---
D
V
--
Y
R
F
L
K
F
F
T
F
M
S
I
E
E
I
N
A
L
-------
E
E
E
D
K
N
S
G
K
A
P
R
A
--
Q
Y
V
L
A
E
Q
V
T
R
L
V
H
G
----------------
E
E
---
G
L
Q
A
A
K
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
69.61
29%
-65
- C3 -
1X8X
2
SYY_ECOLI
A:
[38-322]
-----------------------------------------------
C
G
F
D
P
T
A
D
S
L
H
L
G
H
L
V
P
L
L
C
L
K
R
F
Q
Q
A
G
H
K
P
V
A
L
V
G
G
A
T
G
L
I
G
D
P
S
F
K
A
A
E
R
K
L
N
T
E
-
E
T
V
Q
E
W
V
D
K
I
R
K
Q
----
V
--
A
P
F
L
----
D
FDCG
E
----------
N
S
A
--
I
----
A
A
N
N
Y
D
W
F
G
N
M
N
V
L
T
F
L
R
D
I
G
-
K
H
F
----
S
V
N
Q
M
I
N
K
E
A
V
K
Q
R
L
N
R
E
D
Q
G
I
S
F
T
E
F
S
Y
N
L
L
Q
G
Y
D
----
F
A
C
L
N
K
Q
Y
G
V
V
L
Q
I
G
G
S
D
Q
W
G
N
I
T
S
G
-
I
D
L
T
R
R
--
L
H
Q
N
Q
V
F
G
L
T
V
P
L
I
T
K
A
D
G
T
-
K
F
G
K
T
E
G
-
G
A
V
W
L
D
P
---
K
KTS
P
Y
K
F
Y
Q
F
W
I
N
T
A
D
-
A
---
D
V
--
Y
R
F
L
K
F
F
T
F
M
S
I
E
E
I
N
A
L
-------
E
E
E
D
K
N
S
G
K
A
P
R
A
--
Q
Y
V
L
A
E
Q
V
T
R
L
V
H
G
----------------
E
E
---
G
L
Q
A
A
K
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
69.42
29%
-71
- C3 -
1TYB
1
SYY_GEOSE
E:
[29-303]
-----------------------------------------
E
R
V
T
L
Y
C
G
F
D
P
T
A
D
S
L
H
I
G
H
L
A
G
I
L
T
M
R
R
F
Q
Q
A
G
H
R
P
I
A
L
V
G
G
A
T
G
L
I
G
D
P
S
G
K
K
S
E
R
T
L
N
A
K
-
E
T
V
E
A
W
S
A
R
I
K
E
Q
----
L
--
G
R
F
L
DFEA
D
----
G
----------
N
P
A
--
K
----
I
K
N
N
Y
D
W
I
G
P
L
D
V
I
T
F
L
R
D
V
G
-
K
H
F
----
S
V
N
Y
M
M
A
K
E
S
V
Q
S
R
I
-
E
T
G
--
I
S
F
T
E
F
S
Y
M
M
L
Q
A
Y
D
----
F
L
R
L
YETE
G
C
R
L
Q
I
G
G
S
D
Q
W
G
N
I
T
A
G
-
L
E
L
I
R
K
T
K
G
--
R
A
F
G
-
L
T
I
P
L
V
T
K
A
D
G
T
-
K
F
G
K
T
E
S
-
G
T
I
W
L
D
K
---
E
KTS
P
Y
E
F
Y
Q
F
W
I
N
T
D
D
-
R
---
D
V
--
I
R
Y
L
K
Y
F
T
F
L
S
K
E
E
I
E
A
L
-------
E
Q
E
-
L
R
E
A
P
E
K
R
A
A
Q
K
T
L
A
E
E
V
T
K
L
V
H
G
E
----------------
E
A
---
L
R
Q
A
I
R
I
----
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
68.84
28%
-63
- C3 -
1JIL
1
SYY_STAAE
A:
[24-324]
-------------------------
I
E
----
D
L
L
N
K
-----
E
Q
V
T
L
Y
C
G
A
D
P
T
A
D
S
L
H
I
G
H
L
L
P
F
L
T
L
R
R
F
Q
E
H
G
H
R
P
I
V
L
I
G
G
G
T
G
M
I
G
D
P
S
G
K
S
E
E
R
V
L
Q
T
E
-
E
Q
V
D
K
N
I
E
G
I
S
K
Q
----
M
--
H
N
I
F
----
E
FG--
T
----------
D
H
G
--
A
----
V
L
V
N
N
R
--
D
W
L
G
Q
I
S
L
I
S
F
L
R
-
D
-
Y
GKHV
G
V
N
Y
M
L
G
K
D
S
I
Q
S
R
L
-
E
H
G
--
I
S
Y
T
E
F
T
Y
T
I
L
Q
A
I
D
F
G
H
L
N
R
E
L
----
N
C
K
I
Q
V
G
G
S
D
Q
W
G
N
I
T
S
G
I
E
L
M
R
R
M
Y
G
-
Q
T
D
A
Y
G
-
L
T
I
P
L
V
T
K
S
D
G
-
K
K
F
G
K
S
E
S
-
G
A
V
W
L
D
A
---
E
KTS
P
Y
E
F
Y
Q
F
W
I
N
Q
S
D
-
E
D
V
I
K
F
--
L
K
Y
F
T
F
L
G
K
E
E
I
D
R
L
E
Q
S
-------
K
----
N
E
A
P
H
L
R
E
A
Q
K
T
L
A
E
E
V
T
K
F
I
H
G
E
----------------
D
A
---
L
N
D
A
I
R
I
----
S
Q
A
L
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
68.24
29%
-61
- C3 -
2YXN
1
SYY_ECOLI
A:
[38-322]
-----------------------------------------------
C
G
F
D
P
T
A
D
S
L
H
L
G
H
L
V
P
L
L
C
L
K
R
F
Q
Q
A
G
H
K
P
V
A
L
V
G
G
A
T
G
L
I
G
D
P
S
F
K
A
A
E
R
K
L
N
T
E
-
E
T
V
Q
E
W
V
D
K
I
R
K
Q
----
V
--
A
P
F
L
----
D
FDCG
E
----------
N
S
A
--
I
----
A
A
N
N
Y
D
W
F
G
N
M
N
V
L
T
F
L
R
D
I
G
-
K
H
F
----
S
V
N
Q
M
I
N
K
E
A
V
K
Q
R
L
N
R
E
D
Q
G
I
S
F
T
E
F
S
Y
N
L
L
Q
G
Y
D
----
F
A
C
L
N
K
Q
Y
G
V
V
L
C
I
G
G
S
D
Q
W
G
N
I
T
S
G
-
I
D
L
T
R
R
--
L
H
Q
N
Q
V
F
G
L
T
V
P
L
I
T
K
A
D
G
T
-
K
F
G
K
T
E
G
-
G
A
V
W
L
D
P
---
K
KTS
P
Y
K
F
Y
Q
F
W
I
N
T
A
D
-
A
---
D
V
--
Y
R
F
L
K
F
F
T
F
M
S
I
E
E
I
N
A
L
-------
E
E
E
D
K
N
S
G
K
A
P
R
A
--
Q
Y
V
L
A
E
Q
V
T
R
L
V
H
G
----------------
E
E
---
G
L
Q
A
A
K
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
68.00
29%
-66
- C3 -
1WQ4
1
SYY_ECOLI
A:
[37-321]
-----------------------------------------------
C
G
F
D
P
T
A
D
S
L
H
L
G
H
L
V
P
L
L
C
L
K
R
F
Q
Q
A
G
H
K
P
V
A
L
V
G
G
A
T
G
L
I
G
D
P
S
F
K
A
A
E
R
K
L
N
T
E
-
E
T
V
Q
E
W
V
D
K
I
R
K
Q
----
V
--
A
P
F
L
----
D
FDCG
E
----------
N
S
A
--
I
----
A
A
N
N
Y
D
W
F
G
N
M
N
V
L
T
F
L
R
D
I
G
-
K
H
F
----
S
V
N
Q
M
I
N
K
E
A
V
K
Q
R
L
N
R
E
D
Q
G
I
S
F
T
E
F
S
Y
N
L
L
Q
G
Y
D
----
F
A
C
L
N
K
Q
Y
G
V
V
L
C
I
G
G
S
D
Q
W
G
N
I
T
S
G
-
I
D
L
T
R
R
--
L
H
Q
N
Q
V
F
G
L
T
V
P
L
I
T
K
A
D
G
T
-
K
F
G
K
T
E
G
-
G
A
V
W
L
D
P
---
K
KTS
P
Y
K
F
Y
Q
F
W
I
N
T
A
D
-
A
---
D
V
--
Y
R
F
L
K
F
F
T
F
M
S
I
E
E
I
N
A
L
-------
E
E
E
D
K
N
S
G
K
A
P
R
A
--
Q
Y
V
L
A
E
Q
V
T
R
L
V
H
G
----------------
E
E
---
G
L
Q
A
A
K
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------