@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0034: (2016-03-11 )
MSSERSLSSRFIEGLSIFAQKISSQKHIMAIRDGFAAMIPITIIAAFFLLVNNVLLQPENGLLKFIPNVENYLGVGIQVYNATLGIMAILAAFLIGNFLAKSYGMEGRTEGVIAVAAYVVLIPASSHLMSVDGKAFEAGGVLTQEMTSSTGMFLAIIAALVSITMLAKFSKSKKLKISMPESVPPAIAKSFNILIPSFLVLSILAIIEVLVVSFVSMSIPEIIVKVLQIPLVGGFQTLPGILLYVFLAGFLWVFGIHGAFVLGAISGPVLLTSLQQNIDAVNAGTALPNIVTQPFLDAFVYMGGGGTIICLVIAIFIASKRPDHRMVTKFGLIPSIFNVSEPLMFGLPVVFNPIYGIPLVIAPLASTAMAYFATSWGWISQTYILIPWVTPPVLSGYLATGGDIRASILQIAIIIVGTLIYLPFVLVANRAYVLEQKAAGKVEAVTNGEV
Atome Classification :
(20 SA)
------------------------------.........10......-..-------20........30........---------40.......------.50........60.........--70.-...--..-----------..80...-------...-------------..90.--.....---...---100..---.....110......--.120.....-.---...130...-.....140.......----------150..----------.....160-------.......170----------------.........180.......190---.......200.......210------.........220.-.------.....230---------------........---.----240-------------------.----.....----------.--..-250..---------------.....260..-.....270....--.-..280-.....-...290.......300--------------.......310...------....320--..-.....330-----....--.....340..-..-...350...-----....360-----.......370.--------------------......380..-...-...390.......400--......---------------------...410......---------.420..--------.....430.......440.......450------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------MSS
E
R
S
L
S
S
R
F
I
E
G
L
S
I
-
F
A
-------
Q
K
ISSQK
H
I
M
A
IRDG
F
A
A
M
I
---------
P
I
T
I
I
A
A
F
F
------
L
L
V
N
N
VLLQPEN-
G
L
L
KFIPNV--
E
N
Y
-
L
G
V
--
G
I
-----------
Q
V
Y
N
A
T
L
-------
G
I
M
-------------
A
I
L
-
A
--
A
F
L
I
G
---
N
F
L
---
A
K
S
YG---MEGRTE
G
V
I
A
V
A
A
Y
--
V
V
--
L
IPAS-S---
H
L
M
SV-DG
K
-
A
FEAGG
V
L
T
Q
E
M
TSS----------T
G
M
F
L
----------
A
I
I
A
A
L
V
S
-------
I
T
M
L
A
K
FS------------------KS
K
K
L
K
I
SMPESV
P
P
A
I
A
K
S
F
N
---
I
L
I
P
S
F
L
V
L
S
I
L
A
I
I
E
V
L
--------
V
V
S
F
V
SMS
I
P
E
I
I
-
V
------
K
V
L
QIP-----------------LVGG
F
Q
T
L
---
P
----
G
---------------------
I
----
L
L
Y
V
F
----------
L
--
A
G
-
F
L
W
V
F
---------------GIH
G
A
F
V
L
GA-IS
G
P
V
L
L
T
S
L
Q
Q
--
N
-
I
D
AV--NAGTA-L
P
N
I
V
T
Q
P
F
L
D
A
F
VYM--------------GGG
G
T
I
I
C
L
V
I
A
I
------
F
I
ASKRP--D
H
-
R
M
V
T
K
F-------GL
I
P
--
S
I
FNVSE
P
L
M
-FG-
L
P
V
V
FNPIY-----GI
P
L
V
I
A
-----
P
L
A
S
T
A
M
A
Y
F
A--------------------TSWGW
I
S
Q
-
T
Y
-
I
L
I
-PWVT
P
P
V
L
S
G
Y
LAT----G
G
D
I
R
A
---------------------
S
I
L
Q
I
A
I
I
I
V
G
T
---------
L
I
Y
L
P
F
--------
V
L
VAN
R
A
Y
V
L
EQKAAG
K
V
E
A
VTNGEV--------------------------
3
PsiBlast_CBE
96.70
33%
-142
- C8 -
3QNQ
9
?
C:
[3-424]
---------------------------------------
R
F
L
E
K
Y
V
M
P
V
A
-------
G
K
V
A
E
Q
R
H
L
L
A
I
R
D
G
L
V
L
T
M
---------
P
F
L
I
I
G
S
I
F
------
L
I
I
S
T
L
---
P
I
P
-
G
Y
S
E
F
M
A
S
L
FG
K
N
W
N
V
A
L
--
G
Y
-----------
P
V
-
S
A
T
F
-------
N
I
M
-------------
A
L
I
-
A
--
V
F
G
I
A
---
Y
R
L
---
G
E
Y
Y
K
---
V
D
A
L
A
S
G
A
L
S
L
V
T
F
--
L
L
--
A
T
P
F
Q
V
A
---
Y
I
M
P
G
-
T
K
E
-
S
I
L
V
D
G
V
I
P
A
A
L
M
G
S
----------
Q
G
L
F
V
----------
A
M
I
I
A
I
I
S
--------
T
E
I
Y
R
F
L
------------------
V
Q
K
K
M
I
I
K
M
P
E
T
V
P
P
A
V
T
R
S
F
A
---
A
L
I
P
G
F
I
V
V
T
V
V
W
I
I
R
L
I
--------
F
E
H
T
T
F
G
S
I
H
N
V
V
-
G
------
K
L
L
Q
E
P
-----------------
L
S
I
L
G
A
S
L
---
W
----
G
---------------------
A
----
V
I
A
V
I
----------
L
--
V
H
-
V
L
W
A
C
---------------
G
I
H
G
A
T
I
V
G
G
-
V
M
S
P
I
W
L
S
L
M
D
Q
--
N
-
R
I
A
F
--
Q
A
G
Q
D
-
V
P
N
T
I
T
A
Q
F
F
D
L
W
I
Y
M
--------------
G
G
S
G
A
T
L
A
L
V
V
G
M
------
L
L
F
A
R
S
Q
--
Q
L
-
K
S
L
G
R
L
-------
S
I
A
P
--
G
I
F
N
I
N
E
M
V
T
-
F
G
-
M
P
I
V
M
N
P
L
L
-----
L
I
P
F
I
V
V
-----
P
V
V
L
T
I
V
S
Y
F
A
--------------------
M
E
W
G
L
V
A
R
P
S
G
-
A
A
V
-
T
W
T
T
P
I
L
F
S
G
Y
L
G
S
----
G
G
K
I
S
G
---------------------
V
I
L
Q
L
V
N
F
A
L
A
F
---------
V
I
Y
L
P
F
--------
L
K
I
W
D
K
----------------------------------------------
1
PsiBlast_PDB
96.32
33%
-141
- C8 -
3QNQ
8
?
A:
[3-424]
---------------------------------------
R
F
L
E
K
Y
V
M
P
V
A
-------
G
K
V
A
E
Q
R
H
L
L
A
I
R
D
G
L
V
L
T
M
---------
P
F
L
I
I
G
S
I
F
------
L
I
I
S
T
L
---
P
I
P
-
G
Y
S
E
F
M
A
S
L
FG
K
N
W
N
V
A
L
--
G
Y
-----------
P
V
-
S
A
T
F
-------
N
I
M
-------------
A
L
I
-
A
--
V
F
G
I
A
---
Y
R
L
---
G
E
Y
Y
K
---
V
D
A
L
A
S
G
A
L
S
L
V
T
F
--
L
L
--
A
T
P
F
Q
V
A
---
Y
I
M
P
G
-
T
K
E
-
S
I
L
V
D
G
V
I
P
A
A
L
M
G
S
----------
Q
G
L
F
V
----------
A
M
I
I
A
I
I
S
--------
T
E
I
Y
R
F
L
------------------
V
Q
K
K
M
I
I
K
M
P
E
T
V
P
P
A
V
T
R
S
F
A
---
A
L
I
P
G
F
I
V
V
T
V
V
W
I
I
R
L
I
--------
F
E
H
T
T
F
G
S
I
H
N
V
V
-
G
------
K
L
L
Q
E
P
-----------------
L
S
I
L
G
A
S
L
---
W
----
G
---------------------
A
----
V
I
A
V
I
----------
L
--
V
H
-
V
L
W
A
C
---------------
G
I
H
G
A
T
I
V
G
G
-
V
M
S
P
I
W
L
S
L
M
D
Q
--
N
-
R
I
A
F
--
Q
A
G
Q
D
-
V
P
N
T
I
T
A
Q
F
F
D
L
W
I
Y
M
--------------
G
G
S
G
A
T
L
A
L
V
V
G
M
------
L
L
F
A
R
S
Q
--
Q
L
-
K
S
L
G
R
L
-------
S
I
A
P
--
G
I
F
N
I
N
E
M
V
T
-
F
G
-
M
P
I
V
M
N
P
L
L
-----
L
I
P
F
I
V
V
-----
P
V
V
L
T
I
V
S
Y
F
A
--------------------
M
E
W
G
L
V
A
R
P
S
G
-
A
A
V
-
T
W
T
T
P
I
L
F
S
G
Y
L
G
S
----
G
G
K
I
S
G
---------------------
V
I
L
Q
L
V
N
F
A
L
A
F
---------
V
I
Y
L
P
F
--------
L
K
I
W
D
K
----------------------------------------------
2
PsiBlast_CBE
96.20
33%
-143
- C8 -
3QNQ
7
?
D:
[3-424]
---------------------------------------
R
F
L
E
K
Y
V
M
P
V
A
-------
G
K
V
A
E
Q
R
H
L
L
A
I
R
D
G
L
V
L
T
M
---------
P
F
L
I
I
G
S
I
F
------
L
I
I
S
T
L
---
P
I
P
-
G
Y
S
E
F
M
A
S
L
FG
K
N
W
N
V
A
L
--
G
Y
-----------
P
V
-
S
A
T
F
-------
N
I
M
-------------
A
L
I
-
A
--
V
F
G
I
A
---
Y
R
L
---
G
E
Y
Y
K
---
V
D
A
L
A
S
G
A
L
S
L
V
T
F
--
L
L
--
A
T
P
F
Q
V
A
---
Y
I
M
P
G
-
T
K
E
-
S
I
L
V
D
G
V
I
P
A
A
L
M
G
S
----------
Q
G
L
F
V
----------
A
M
I
I
A
I
I
S
--------
T
E
I
Y
R
F
L
------------------
V
Q
K
K
M
I
I
K
M
P
E
T
V
P
P
A
V
T
R
S
F
A
---
A
L
I
P
G
F
I
V
V
T
V
V
W
I
I
R
L
I
--------
F
E
H
T
T
F
G
S
I
H
N
V
V
-
G
------
K
L
L
Q
E
P
-----------------
L
S
I
L
G
A
S
L
---
W
----
G
---------------------
A
----
V
I
A
V
I
----------
L
--
V
H
-
V
L
W
A
C
---------------
G
I
H
G
A
T
I
V
G
G
-
V
M
S
P
I
W
L
S
L
M
D
Q
--
N
-
R
I
A
F
--
Q
A
G
Q
D
-
V
P
N
T
I
T
A
Q
F
F
D
L
W
I
Y
M
--------------
G
G
S
G
A
T
L
A
L
V
V
G
M
------
L
L
F
A
R
S
Q
--
Q
L
-
K
S
L
G
R
L
-------
S
I
A
P
--
G
I
F
N
I
N
E
M
V
T
-
F
G
-
M
P
I
V
M
N
P
L
L
-----
L
I
P
F
I
V
V
-----
P
V
V
L
T
I
V
S
Y
F
A
--------------------
M
E
W
G
L
V
A
R
P
S
G
-
A
A
V
-
T
W
T
T
P
I
L
F
S
G
Y
L
G
S
----
G
G
K
I
S
G
---------------------
V
I
L
Q
L
V
N
F
A
L
A
F
---------
V
I
Y
L
P
F
--------
L
K
I
W
D
K
----------------------------------------------
4
PsiBlast_CBE
96.06
33%
-140
- C8 -
3QNQ
7
?
B:
[3-424]
---------------------------------------
R
F
L
E
K
Y
V
M
P
V
A
-------
G
K
V
A
E
Q
R
H
L
L
A
I
R
D
G
L
V
L
T
M
---------
P
F
L
I
I
G
S
I
F
------
L
I
I
S
T
L
---
P
I
P
-
G
Y
S
E
F
M
A
S
L
FG
K
N
W
N
V
A
L
--
G
Y
-----------
P
V
-
S
A
T
F
-------
N
I
M
-------------
A
L
I
-
A
--
V
F
G
I
A
---
Y
R
L
---
G
E
Y
Y
K
---
V
D
A
L
A
S
G
A
L
S
L
V
T
F
--
L
L
--
A
T
P
F
Q
V
A
---
Y
I
M
P
G
-
T
K
E
-
S
I
L
V
D
G
V
I
P
A
A
L
M
G
S
----------
Q
G
L
F
V
----------
A
M
I
I
A
I
I
S
--------
T
E
I
Y
R
F
L
------------------
V
Q
K
K
M
I
I
K
M
P
E
T
V
P
P
A
V
T
R
S
F
A
---
A
L
I
P
G
F
I
V
V
T
V
V
W
I
I
R
L
I
--------
F
E
H
T
T
F
G
S
I
H
N
V
V
-
G
------
K
L
L
Q
E
P
-----------------
L
S
I
L
G
A
S
L
---
W
----
G
---------------------
A
----
V
I
A
V
I
----------
L
--
V
H
-
V
L
W
A
C
---------------
G
I
H
G
A
T
I
V
G
G
-
V
M
S
P
I
W
L
S
L
M
D
Q
--
N
-
R
I
A
F
--
Q
A
G
Q
D
-
V
P
N
T
I
T
A
Q
F
F
D
L
W
I
Y
M
--------------
G
G
S
G
A
T
L
A
L
V
V
G
M
------
L
L
F
A
R
S
Q
--
Q
L
-
K
S
L
G
R
L
-------
S
I
A
P
--
G
I
F
N
I
N
E
M
V
T
-
F
G
-
M
P
I
V
M
N
P
L
L
-----
L
I
P
F
I
V
V
-----
P
V
V
L
T
I
V
S
Y
F
A
--------------------
M
E
W
G
L
V
A
R
P
S
G
-
A
A
V
-
T
W
T
T
P
I
L
F
S
G
Y
L
G
S
----
G
G
K
I
S
G
---------------------
V
I
L
Q
L
V
N
F
A
L
A
F
---------
V
I
Y
L
P
F
--------
L
K
I
W
D
K
----------------------------------------------
5
HHSearch
95.88
31%
-142
- C8 -
3QNQ
8
?
A:
[3-434]
--------------------------------------
R
F
L
E
K
Y
V
M
P
-
V
A
-------
G
K
V
A
E
Q
R
H
L
L
A
I
R
D
G
L
V
L
T
M
---------
P
F
L
I
I
G
S
I
F
------
L
I
I
S
T
L
P
-
I
P
G
Y
S
E
F
M
A
S
-
L
F
G
--
K
N
W
-
N
V
A
--
L
G
-----------
Y
P
V
S
A
T
F
-------
N
I
M
-------------
A
L
I
-
A
--
V
F
G
I
A
---
Y
R
L
---
G
E
Y
Y
K
---
V
D
A
L
A
S
G
A
L
S
L
V
T
F
--
L
L
--
A
T
P
F
Q
-
V
---
A
Y
I
M
P
-
G
T
K
E
S
I
L
V
D
G
V
I
P
A
A
L
M
G
S
----------
Q
G
L
F
V
----------
A
M
I
I
A
I
I
S
-------
T
E
I
Y
R
F
L
V
------------------
Q
K
-
K
M
I
I
K
M
P
E
T
V
P
P
A
V
T
R
S
F
A
---
A
L
I
P
G
F
I
V
V
T
V
V
W
I
I
R
L
I
--------
F
E
H
T
T
F
G
S
I
H
N
V
V
-
G
------
K
L
L
Q
E
P
-----------------
L
S
I
L
G
A
S
L
---
W
----
G
---------------------
A
----
V
I
A
V
I
----------
L
--
V
H
-
V
L
W
A
C
---------------
G
I
H
G
A
T
I
V
G
G
-
V
M
S
P
I
W
L
S
L
M
D
Q
--
N
-
R
I
A
F
--
Q
A
G
Q
D
-
V
P
N
T
I
T
A
Q
F
F
D
L
W
I
Y
M
--------------
G
G
S
G
A
T
L
A
L
V
V
G
M
------
L
L
F
A
R
S
Q
--
Q
L
-
K
S
L
G
R
L
-------
S
I
A
P
--
G
I
F
N
I
N
E
M
V
T
-
F
G
-
M
P
I
V
M
N
P
L
L
-----
L
I
P
F
I
V
V
-----
P
V
V
L
T
I
V
S
Y
F
A
--------------------
M
E
W
G
L
V
A
R
-
P
S
G
A
A
V
-
T
W
T
T
P
I
L
F
S
G
Y
L
G
S
----
G
G
K
I
S
G
---------------------
V
I
L
Q
L
V
N
F
A
L
A
F
---------
V
I
Y
L
P
F
--------
L
K
I
W
D
K
Q
K
I
A
E
E
K
G
E
A
------------------------------------
14
Fugue
95.86
30%
-141
- C8 -
3QNQ
8
?
A:
[3-434]
--------------------------------------
R
F
L
E
K
Y
V
M
P
-
V
A
-------
G
K
V
A
E
Q
R
H
L
L
A
I
R
D
G
L
V
L
T
M
---------
P
F
L
I
I
G
S
I
F
------
L
I
I
S
T
L
P
I
P
G
Y
S
-
E
F
M
A
S
L
F
G
---
K
N
W
-
N
V
A
--
L
G
-----------
Y
P
V
S
A
T
F
-------
N
I
M
-------------
A
L
I
-
A
--
V
F
G
I
A
---
Y
R
L
---
G
E
Y
Y
K
---
V
D
A
L
A
S
G
A
L
S
L
V
T
F
--
L
L
--
A
T
P
F
Q
-
V
---
A
Y
I
M
P
G
T
K
E
-
S
I
L
V
D
G
V
I
P
A
A
L
M
G
S
----------
Q
G
L
F
V
----------
A
M
I
I
A
I
I
S
-------
T
E
I
Y
R
F
L
V
------------------
Q
-
K
K
M
I
I
K
M
P
E
T
V
P
P
A
V
T
R
S
F
A
---
A
L
I
P
G
F
I
V
V
T
V
V
W
I
I
R
L
I
--------
F
E
H
T
T
F
G
S
I
H
N
V
V
-
G
------
K
L
L
Q
E
P
-----------------
L
S
I
L
G
A
S
L
---
W
----
G
---------------------
A
----
V
I
A
V
I
----------
L
--
V
H
-
V
L
W
A
C
---------------
G
I
H
G
A
T
I
V
G
G
-
V
M
S
P
I
W
L
S
L
M
D
Q
--
N
-
R
I
A
F
--
Q
A
G
Q
D
-
V
P
N
T
I
T
A
Q
F
F
D
L
W
I
Y
M
--------------
G
G
S
G
A
T
L
A
L
V
V
G
M
------
L
L
F
A
R
S
Q
--
Q
L
-
K
S
L
G
R
L
-------
S
I
A
P
--
G
I
F
N
I
N
E
M
V
T
-
F
G
-
M
P
I
V
M
N
P
L
L
-----
L
I
P
F
I
V
V
-----
P
V
V
L
T
I
V
S
Y
F
A
--------------------
M
E
W
G
L
V
A
R
-
P
S
G
A
A
V
-
T
W
T
T
P
I
L
F
S
G
Y
L
G
S
----
G
G
K
I
S
G
---------------------
V
I
L
Q
L
V
N
F
A
L
A
F
---------
V
I
Y
L
P
F
--------
L
K
I
W
D
K
Q
K
I
A
E
E
K
G
E
A
------------------------------------
23
Fugue
63.75
18%
-148
- C3 -
4M1K
2
?
A:
[6-688]
EYDLKR
L
R
N
I
G
I
A
A
H
IDAG
K
T
T
T
T
E
R
I
L
Y
Y
T
G
R
I
A
A
V
T
T
C
F
W
K
D
H
R
I
-
N
I
I
DTPGHV
D
F
T
I
E
V
E
R
S
M
R
V
L
D
G
A
I
V
V
F
DSSQGVE
P
Q
S
E
T
V
W
R
Q
A
E
K
Y
K
V
P
R
I
A
F
A
N
K
M
D
K
T
G
A
-
D
L
W
L
V
I
R
T
M
--
Q
E
R
-
L
G
A
--
R
P
-----------
V
V
M
Q
L
P
I
G
REDTFS
G
I
I
-------------
D
V
L
-
R
M
K
A
Y
T
Y
G
---
N
D
L
GTD
I
R
E
I
P
---
I
P
E
E
Y
L
D
Q
A
R
E
Y
H
E
--
K
L
--
V
E
V
A
A
-
D
---
F
D
E
N
I
-
M
L
K
-
Y
L
E
G
E
E
P
T
E
E
E
L
V
A
A
I
R
K
G
T
I
D
LK
I
T
P
V
F
L
G
S
ALKNKG
V
Q
L
L
L
D
A
V
V
D
YLPSPLD
I
P
P
I
K
G
T
T
------------------
P
E
G
E
V
V
E
I
H
P
D
P
N
G
P
L
A
A
L
A
F
K
---
I
M
A
D
P
Y
V
--
G
R
L
T
F
I
R
V
Y
S
G
T
L
T
S
G
S
Y
V
Y
N
T
T
K
G
R
K
E
R
V
-
A
------
R
L
L
R
M
H
AN
H
R
E
E
V
EELKAG
D
L
G
A
V
V
G
L
K
E
T
I
---
T
----
G
D
T
L
V
GEDAPRVIL
E
S
I
E
V
P
EP
V
----
I
D
V
A
I
EPKTKADQEK
L
--
S
Q
-
A
L
A
R
L
A
E
E
D
PT
F
R
V
S
THPET
G
Q
T
I
I
S
G
M
G
E
-
L
H
L
E
I
I
V
D
R
L
K
R
EF
K
-
V
D
A
N
VG
K
P
Q
V
A
-
Y
R
E
T
I
T
K
P
V
D
V
E
G
K
F
I
R
L
T-----------
G
G
R
G
Q
Y
G
H
V
K
I
K
V
------
E
P
L
P
R
G
S
--
G
F
-
E
F
V
N
A
I
VGGVIPK
E
Y
I
P
--
A
V
Q
K
G
I
E
E
A
M
-
Q
S
-
G
P
L
I
G
F
P
V
V
-----
D
I
K
V
T
L
Y
D
G
S
Y
H
E
V
D
S
S
E
M
A
F
K
I
--------------------
A
G
S
M
A
I
K
E
-
A
V
-
Q
K
G
D
P
V
I
L
E
P
I
M
R
V
E
V
T
T
PEEY
M
G
D
V
I
G
---------------------
D
L
N
A
R
R
G
Q
I
L
G
M
E
P
R
GN
A
Q
V
I
R
A
F
V
P
L
--------
A
E
M
F
G
Y
A
T
D
L
R
S
K
T
Q
G
R
G
S
F
V
M
F
F
D
H
Y
Q
E
V
P
K
Q
V
Q
E
K
LI-------------
22
Fugue
62.98
15%
-114
- C6 -
4UI9
-
ANC2_HUMAN
N:
[15-730]
------------RPGQELLVAWNTVSTEEL
R
A
A
V
E
V
L
R
G
H
V
L
E
E
W
F
V
-
E
V
-------
L
Q
N
D
L
Q
A
N
I
S
P
E
F
W
N
A
I
S
Q
C
---------
E
N
S
A
C
L
L
L
L
------
L
D
A
F
G
L
L
E
S
R
L
D
-
P
Y
L
R
S
L
E
L
L
--
E
K
W
-
T
R
L
--
G
L
LMGTGAQGLRE
E
V
H
T
M
L
R
-------
G
V
L
FFSTPRTFQEMIQ
R
L
Y
-
G
--
C
F
L
R
V
---
Y
M
Q
---
S
K
R
K
G
DPE
L
E
G
E
L
D
S
R
Y
A
R
R
R
Y
--
Y
R
--
L
L
Q
S
P
-
L
WCR
Q
A
L
E
Q
-
F
H
Q
-
L
S
Q
V
L
H
R
L
S
L
L
E
R
V
S
----------
A
E
A
V
T
----------
T
T
L
H
Q
V
T
R
-------
E
R
M
E
D
R
C
R
GEYERSFLREFHKWIERV
V
G
W
L
G
K
V
F
T
L
R
R
W
R
C
H
V
Q
R
F
F
Y
---
R
I
Y
A
S
L
R
I
E
E
L
F
S
I
V
R
D
F
--------
P
D
S
R
P
A
I
E
D
L
K
Y
C
-
L
ERTDQR
Q
Q
L
L
V
S
-----------------
L
K
A
A
L
E
T
R
LLH
P
----
G
---------------------
V
NTCD
I
I
T
L
Y
----------
I
--
S
A
-
I
K
A
L
R
---------------
V
I
D
P
S
M
V
I
L
E
-
V
A
C
E
P
I
R
R
Y
L
R
T
--
R
-
E
D
T
V
--
R
Q
I
V
A
G
L
T
D
L
A
V
E
L
S
K
E
P
E
D
W
V
PDPVDADPGKSSSK
R
R
S
S
D
I
I
S
L
L
V
S
I
YGSKDL
F
I
N
E
Y
R
S
LL
A
D
-
R
L
L
H
Q
F
-------
S
F
S
P
ER
E
I
R
N
V
E
L
L
K
L
R
F
G
E
A
P
M
H
F
C
E
V
M
-----
L
K
D
M
A
D
S
-----
R
R
I
N
A
N
I
R
E
E
D
EKRPAEEQPPFGVYAVILSS
E
F
W
P
P
F
K
D
-
E
K
-
L
E
V
-
P
E
D
I
R
A
A
L
E
A
Y
C
K
K
----
Y
E
Q
L
K
A
MRTLSWKHTLGLVTMDVELAD
R
T
L
S
V
A
V
T
P
V
Q
A
---------
V
I
L
L
Y
F
QDQASWTL
E
E
L
S
K
A
V
K
M
P
V
A
L
L
R
R
R
M
S
V
W
L
Q
Q
G
V
LREEPPGTFSVIEEERPQDRDNMVLI
16
Fugue
62.42
23%
-130
- C7 -
4QPP
3
ANM6_HUMAN
A:
[48-376]
-------------------------------------
Y
Y
E
C
Y
S
D
V
S
V
-
H
E
-------
E
M
I
A
D
R
V
R
T
D
A
Y
R
L
G
I
L
R
-----------------------------
N
W
A
A
L
R
G
K
--------------
T
V
-
L
D
V
--
G
----------------
A
G
T
-------
G
I
L
-------------
S
I
F
-
C
--
A
Q
A
G
A
---
R
------
R
V
Y
A
---
V
E
A
S
A
--
I
W
Q
Q
A
R
E
--
V
V
--
R
F
N
G
L
-
E
---
D
R
V
H
V
-
L
P
------
G
P
V
E
T
V
E
L
P
E
Q
-------------
V
D
----------
A
I
V
S
E
W
M
G
-------
Y
G
L
L
H
E
---------------------------
S
M
L
S
S
V
L
H
A
R
T
K
W
L
K
EGG
L
L
L
P
A
S
A
E
L
F
I
V
P
I
--------------
S
D
Q
M
L
E
W
R
L
G
F
-
W
------
S
Q
V
K
Q
H
-----------------
Y
G
V
D
M
S
C
L
---
E
----
G
---------------------
F
----
A
T
R
C
L
----------
M
--
G
H
S
E
I
V
V
Q
---------------
G
L
S
G
E
D
V
L
----
A
R
P
Q
R
F
A
Q
L
E
---------------------
L
S
R
A
G
L
E
Q
E
L
E
A
--------------
G
V
G
G
R
F
R
C
S
C
Y
G
--------------------------------------------
S
A
P
M
-
H
G
-
F
A
I
W
F
Q
V
T
F
P
GGES
E
K
P
L
V
L
S
---------
T
S
P
F
H
P
A
--------------------
T
H
W
K
-
Q
A
L
-
L
Y
-
L
N
E
-
P
V
Q
V
E
Q
------------
D
T
D
V
S
--------------------------------
G
E
---------
I
T
L
L
P
S
--------
R
D
N
P
R
R
L
R
V
L
L
R
Y
K
V
G
D
Q
E
E
K
T
K
D
F
A
M
ED-----------------------
15
Fugue
60.92
21%
-119
- C7 -
1XIP
-
NU159_YEAST
A:
[1-381]
-----------------------------A
S
S
L
K
D
E
V
P
T
E
T
S
E
D
----
F
G
-------
F
K
F
L
G
Q
K
Q
I
L
P
---
S
F
N
E
K
L
---------
P
-------
F
------
A
S
L
Q
N
L
D
I
S
--
N
-
S
K
S
L
F
V
A
A
S
--
G
S
-----------------------
K
A
V
V
-------
G
E
L
-------------
Q
L
L
-
R
--
D
H
I
T
S
---
D
S
T
---
P
L
T
F
K
---
W
E
K
E
I
P
D
V
I
F
V
C
F
H
GD
Q
V
--
L
V
S
T
R
-
N
---
A
L
Y
S
L
-
D
L
E
-
E
L
S
E
F
R
T
V
T
S
-
F
E
K
P
----------
V
F
Q
L
K
----------
N
V
N
N
T
L
V
I
-------
L
N
-----
S
------------------
V
N
D
L
S
A
L
D
L
R
T
K
S
T
K
Q
L
A
Q
N
-------
V
T
S
F
D
V
T
N
S
Q
L
A
V
L
L
K
--------
D
R
S
F
Q
S
F
A
W
R
N
G
E
M
E
------
K
Q
F
E
F
S
-----------------
L
P
S
E
L
E
E
L
---
P
VEEY
S
---------------------
P
----
L
S
V
T
I
----------
L
SP
Q
D
-
F
L
A
V
F
---------------
G
-------
N
V
-
I
S
E
T
D
D
E
V
S
Y
D
Q
--
K
M
Y
I
I
K
--
H
I
D
G
-------
S
A
S
F
Q
E
T
F
D
I
T
--------------
P
P
F
G
Q
I
V
-----------------
R
F
--
P
Y
M
Y
K
V
T
L
S
-------
G
L
I
E
--
P
D
A
N
V
N
--
V
L
-
A
S
-
S
C
S
S
E
V
S
I
W
-----
D
S
K
Q
V
I
E
-----
P
S
Q
D
S
E
R
A
V
L
P
--------------------
I
S
---------------------------
E
----
E
T
D
K
D
T
---------------------
N
P
I
G
V
A
V
D
V
V
T
S
---------
G
--
L
P
L
--------
V
Y
I
L
N
N
E
--------
G
S
L
Q
I
V
G
L
F
H
---------------------------
19
Fugue
49.76
11%
-116
- C4 -
1B9H
1
RIFK_AMYMS
A:
[5-388]
------------------------------------
K
A
P
E
F
P
A
W
P
Q
Y
-
D
D
-------
A
E
R
N
G
L
V
R
A
L
E
-----------------------------------
Q
G
Q
W
W
R
M
G
G
D
-
E
V
N
S
F
E
R
E
F
--
A
A
H
-
H
G
A
A
H
A
L
-----------
A
V
T
N
G
T
H
-------
A
L
E
-------------
L
A
L
-
Q
--
V
M
G
V
G
PG
T
E
V
I
---
V
P
A
F
T
---
F
I
S
S
S
Q
A
A
Q
R
L
G
A
V
--
T
V
--
P
V
D
V
D
-
A
---
A
T
Y
N
L
-
D
P
E
-
A
V
A
A
A
------
V
T
P
R
----------
T
K
V
I
M
----------
P
V
H
M
A
G
L
M
-------
A
D
M
D
A
L
A
K
------------------
I
S
A
D
T
G
V
P
L
L
Q
D
A
A
H
A
H
G
A
R
W
Q
---
G
-------
K
R
V
G
E
L
D
S
I
A
--------
T
F
S
F
Q
N
--------
G
------
K
L
M
T
A
G
-----------------
E
G
G
A
V
V
F
P
---
D
----
G
------------------------------
E
----------
T
--
E
K
-
Y
E
T
A
F
---------------
L
R
H
S
C
G
R
P
R
D
D
R
R
Y
F
H
K
I
A
G
S
N
M
--
R
-
L
N
E
F
--
S
A
S
V
L
-
R
A
Q
L
A
R
---------------------------------
L
D
E
Q
------
I
A
V
R
D
E
R
--
W
T
-
L
L
S
R
L
L
-------
G
A
I
D
--
G
V
V
P
Q
G
G
D
V
R
-
A
D
-
R
N
S
H
Y
M
A
M
F
-----
R
I
P
G
L
T
E
-----
E
R
R
N
A
L
V
D
R
L
V
--------------------
E
A
G
L
P
A
F
A
-
A
F
-
R
A
I
-
Y
R
T
D
A
F
W
E
L
G
A
P
D
E
----
S
V
D
A
I
A
---------------------
R
R
C
P
N
T
D
A
I
S
S
D
---------
C
V
W
L
H
H
--------
R
V
L
L
A
G
E
P
E
L
H
A
T
A
E
I
I
A
D
A
V
A
R
A
----------------------------
21
Fugue
46.30
13%
-82
- C5 -
1W5C
9
PSBD_THEEB
D:
[1-350]
--------------------------------
M
T
I
A
I
G
R
A
P
A
E
R
G
W
------------------------------------------------------------------
F
-
D
I
L
D
D
W
L
K
R
--
D
R
F
-
V
F
V
--
G
W
-----------
S
G
I
L
L
F
P
-------
C
A
Y
-------------
L
A
L
-
G
--
G
W
L
T
G
---
T
T
F
---
V
T
S
W
Y
---
T
H
G
L
A
S
S
Y
L
E
G
C
N
F
--
L
T
VA
V
S
T
P
A
-
N
---
S
M
G
H
S
-
L
L
L
-
L
W
G
P
E
A
Q
G
D
F
T
R
W
C
Q
----------
L
G
G
L
W
----------
T
F
I
A
L
H
G
A
-------
F
G
L
I
G
F
M
L
------------------
R
Q
F
E
I
A
R
L
V
--
G
V
R
P
Y
N
A
I
A
F
S
---
A
P
I
A
V
F
V
S
V
F
L
I
Y
P
L
G
Q
------------------------------
S
S
W
F
F
A
-----------------
P
S
F
G
V
A
A
I
---
F
----
R
---------------------
F
----
L
L
F
F
Q
----------
G
--
F
H
-
N
W
T
L
N
---------------
P
F
H
M
M
G
V
A
G
V
-
L
G
G
A
L
L
C
A
I
H
G
A
--
T
-
V
E
N
T
--
L
-----
F
Q
D
G
E
G
A
S
T
F
R
A
F
N
P
T
--------------
Q
A
E
E
T
------------------------
Y
-
S
M
V
T
A
N
-------
R
F
W
S
--
Q
I
F
G
I
A
F
S
N
K
-
R
W
-
L
H
F
F
M
L
F
V
P
-----
V
T
G
L
W
M
S
-----
A
I
G
V
V
G
L
A
L
N
L
--------------------
R
S
Y
D
F
I
S
Q
-
E
I
-
R
A
A
-
E
---
D
P
E
F
E
T
F
Y
T
K
----
N
L
L
L
N
E
---------------------
G
I
R
A
W
M
A
P
Q
D
Q
P
---------
H
E
N
F
V
F
------------------------
P
E
E
V
L
P
R
G
N
---------------------------
17
Fugue
40.77
18%
-75
* C7 *
2AO9
-
?
A:
[13-132]
-----------------------------------------------------------------
M
M
A
K
L
D
E
L
K
Q
K
L
---------
T
A
K
Q
I
Q
A
A
Y
------
L
L
V
E
N
E
L
M
E
E
E
K
--------
R
T
--
Q
D
E
-
M
A
N
--
E
L
-----------
G
I
N
R
T
T
L
-------
W
E
W
-------------
R
T
K
N
Q
--
D
F
I
A
F
---
K
S
E
---
V
A
D
S
F
---
L
A
E
K
R
E
Q
V
Y
S
K
L
M
Q
--
L
I
--
L
G
P
Q
P
-
S
-----
V
K
A
-
M
Q
L
-
Y
M
Q
R
F
G
L
L
T
D
K
K
V
I
E
----------
G
D
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
36.21
22%
205
- C8 -
2QZC
1
?
A:
[4-38]
---------------------------------
I
V
G
N
V
E
N
L
I
N
G
V
G
E
-
L
W
-------
N
K
Y
V
K
H
E
F
I
L
K
M
R
D
G
S
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
33.54
33%
531
* C8 *
1LYP
-
A:
[7-24]
----------------------------------
R
K
F
R
N
K
I
K
E
K
L
K
K
-
I
G
-------
Q
K
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
30.84
12%
191
- C8 -
2B6O
-
MIP_SHEEP
A:
[201-225]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
W
V
Y
---------------------
W
V
G
P
V
I
G
A
G
L
G
S
---------
L
L
Y
D
F
L
--------
L
F
P
-------------------------------------------------
9
HHSearch
29.11
21%
618
- C2 -
2KBV
-
SL9A1_HUMAN
A:
[449-462]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
F
-
I
I
A
Y
G
---------------
G
L
R
G
A
I
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
23.52
12%
422
- C8 -
1LBJ
-
A:
[1-17]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
V
P
I
--------
F
T
Y
G
E
L
Q
R
M
Q
E
K
E
---------------------------------------
8
HHSearch
22.03
17%
142
- C8 -
1HGV
-
CAPSD_BPH75
A:
[14-43]
----------------------------------------------------------------------------------------------------------------------------------
N
Y
--
I
Q
-----------
A
I
A
A
A
G
V
-------
G
V
L
-------------
A
L
A
-
I
--
G
L
S
A
A
---
W
K
Y
---
A
K
R
F
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
11.02
6%
578
- C8 -
2KNC
-
ITA2B_HUMAN
A:
[987-1003]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
W
K
V
G
F
--------
F
K
R
N
R
P
P
L
E
E
D
-----------------------------------------