@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0547: (2016-03-16 )
MKWEEKRDMVKIATWYYHYGWTQAQIAKKIGISRSIISKTLQRAKDLGIVEIFIKDETYYTVDLEQKLEEKFGLEEAIVVATHDMSEEEALNFLAKEAAYTLSKRIAKVKTLGISWGKTIRKFANEFPFIPHKDLTIIPLIGGMGSSDIDLHSNQICYDLKKKMKCHSKYLYAPALVEDTEMKTDLSKNKYISEVLEEGKTVDMAIVGVSSPYNHSTMEEIGYINSEDIEELRYKDVVGDINSRFFTADGKEAKTEINTHVIGLSLEELKNIPTVVALANGLQKKEALVAALNAGLIDVIVITDRMAEYILQKND
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80.....-...90........100.......-110......-.120.....-..130-.-.......140.-..-..-..150........160.......170.......180.......190.......200.......210.........220.......230....-...240.-......250.......260.........270.......280.......290...-....300.......310...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MK
W
E
E
K
R
D
M
V
K
I
A
T
W
Y
Y
HYGW
T
Q
A
Q
I
A
K
K
IGI
S
R
S
I
I
S
K
T
L
Q
R
A
KDL
G
I
V
E
I
F
IKDE
T
Y
Y
T
V
D
L
E
Q
K
L
E
E
KFGLE
E
A
I
V
V
ATHDM
S
-
E
E
E
A
L
N
F
L
A
K
E
A
A
Y
T
L
S
K
R
I
A
K
V
-
K
TLGI
S
W
G
K
-
T
I
R
K
F
A
N
EF-PFIP--H-KD
L
T
I
I
P
L
IGG-MG-SS-DIDL-HSN
Q
I
C
Y
D
L
K
K
K
M
K
C
H
S
K
Y
LYAPALVED
T
E
MKTDLSK
N
K
Y
I
S
E
V
L
EEGK
T
V
D
M
A
I
V
GVS--SPYNH
S
T
M
E
E
IGYI
N
S
E
D
I
E
E
L
R
Y
K
D
-
V
V
GDINS-
R
F
FTADGKEAK
T
E
IN
T
H
--
V
IGL
S
L
E
E
L
KNI
P
T
V
V
A
L
A
NG
L
Q
K
K
E
A
L
V
A
A
L
NAG-
L
I
D
V
I
V
I
T
D
R
M
A
E
Y
I
L
QKND
22
PsiBlast_PDB
99.29
97%
-120
- C9 -
4R9N
-
?
A:
[4-254]
------------------------------------------------------------
T
V
D
L
E
Q
K
L
E
E
K
F
G
L
E
E
A
I
V
V
A
T
H
D
M
S
-
E
E
E
A
L
N
F
L
A
K
E
A
A
Y
T
L
S
K
R
I
A
K
V
-
K
T
L
G
I
S
W
G
K
-
T
I
R
K
F
A
N
E
F
-
P
F
I
P
--
H
-
K
D
L
T
I
I
P
L
I
G
G
---------
D
L
-
H
S
N
Q
I
C
Y
D
L
K
K
K
M
K
C
H
S
K
Y
L
Y
A
P
A
L
V
E
D
T
E
M
K
T
D
L
S
K
N
K
Y
I
S
E
V
L
E
E
G
K
T
V
D
M
A
I
V
G
V
S
--
S
P
Y
N
H
S
T
M
E
E
I
G
Y
I
N
S
E
D
I
E
E
L
R
Y
K
D
-
V
V
G
D
I
N
S
-
R
F
F
T
A
D
G
K
E
A
K
T
E
I
N
T
H
--
V
I
G
L
S
L
E
E
L
K
N
I
P
T
V
V
A
L
A
N
G
L
Q
K
K
E
A
L
V
A
A
L
N
A
G
-
L
I
D
V
I
V
I
T
D
R
M
A
E
Y
I
L
----
103
Fugue
82.29
29%
-96
- C9 -
2W48
3
SORC_KLEPN
A:
[4-315]
--
S
D
D
I
R
L
I
V
K
I
A
Q
L
Y
Y
E
Q
D
M
T
Q
A
Q
I
A
R
E
L
G
I
Y
R
T
T
I
S
R
L
L
K
R
G
R
E
Q
G
I
V
T
I
A
I
N
Y
D
Y
N
E
N
L
W
L
E
Q
Q
L
K
Q
K
F
G
L
K
E
A
V
V
A
S
----
S
-
E
E
E
Q
L
S
A
M
G
Q
H
G
A
L
L
V
D
R
L
L
E
P
G
-
D
I
I
G
F
S
W
G
R
-
A
V
R
S
L
V
E
N
L
-
P
Q
R
S
--
Q
S
R
Q
V
I
C
V
P
I
I
G
G
-
P
S
G
K
L
-
E
S
R
Y
-
H
V
N
T
L
T
Y
G
A
A
A
R
L
K
A
E
S
H
L
A
D
F
P
A
L
L
D
N
P
L
I
R
N
G
I
M
Q
S
Q
H
F
K
T
I
S
S
Y
W
D
S
L
D
V
A
L
V
G
I
G
--
S
P
A
I
R
D
G
A
N
W
H
A
F
Y
G
S
E
E
S
D
D
L
N
A
R
H
-
V
A
G
D
I
C
S
-
R
F
Y
D
I
N
G
G
L
V
D
T
N
M
S
E
K
--
T
L
S
I
E
M
A
K
L
R
Q
A
R
Y
S
I
G
I
A
M
G
E
E
K
Y
S
G
I
L
G
A
L
H
G
R
-
Y
I
N
C
L
V
T
N
R
E
T
A
E
L
L
L
K
---
23
PsiBlast_PDB
81.63
28%
-98
- C9 -
2W48
3
SORC_KLEPN
A:
[8-315]
------
R
L
I
V
K
I
A
Q
L
Y
Y
E
Q
D
M
T
Q
A
Q
I
A
R
E
L
G
I
Y
R
T
T
I
S
R
L
L
K
R
G
R
E
Q
G
I
V
T
I
A
I
N
Y
D
Y
N
E
N
L
W
L
E
Q
Q
L
K
Q
K
F
G
L
K
E
A
V
V
A
S
S
-----
E
E
E
Q
L
S
A
M
G
Q
H
G
A
L
L
V
D
R
L
L
E
P
G
-
D
I
I
G
F
S
W
G
R
-
A
V
R
S
L
V
E
N
L
-
P
Q
R
S
--
Q
S
R
Q
V
I
C
V
P
I
I
G
G
P
S
G
-
K
L
-
E
S
R
Y
-
H
V
N
T
L
T
Y
G
A
A
A
R
L
K
A
E
S
H
L
A
D
F
P
A
L
L
D
N
P
L
I
R
N
G
I
M
Q
S
Q
H
F
K
T
I
S
S
Y
W
D
S
L
D
V
A
L
V
G
I
G
--
S
P
A
I
R
D
G
A
N
W
H
A
F
Y
G
S
E
E
S
D
D
L
N
A
R
H
-
V
A
G
D
I
C
S
-
R
F
Y
D
I
N
G
G
L
V
D
T
N
M
S
E
K
--
T
L
S
I
E
M
A
K
L
R
Q
A
R
Y
S
I
G
I
A
M
G
E
E
K
Y
S
G
I
L
G
A
L
H
G
R
-
Y
I
N
C
L
V
T
N
R
E
T
A
E
L
L
L
K
---
1
HHSearch
81.44
28%
-96
- C9 -
2W48
3
SORC_KLEPN
A:
[4-315]
--
S
D
D
I
R
L
I
V
K
I
A
Q
L
Y
Y
E
Q
D
M
T
Q
A
Q
I
A
R
E
L
G
I
Y
R
T
T
I
S
R
L
L
K
R
G
R
E
Q
G
I
V
T
I
A
I
N
Y
D
Y
N
E
N
L
W
L
E
Q
Q
L
K
Q
K
F
G
L
K
E
A
V
V
A
S
S
-----
E
E
E
Q
L
S
A
M
G
Q
H
G
A
L
L
V
D
R
L
L
E
P
G
-
D
I
I
G
F
S
W
G
R
-
A
V
R
S
L
V
E
N
L
-
P
Q
R
S
Q-
S
-
R
Q
V
I
C
V
P
I
I
G
G
-
P
S
-
G
K
L
E
S
R
Y
-
H
V
N
T
L
T
Y
G
A
A
A
R
L
K
A
E
S
H
L
A
D
F
P
A
L
L
D
N
P
L
I
R
N
G
I
M
Q
S
Q
H
F
K
T
I
S
S
Y
W
D
S
L
D
V
A
L
V
G
I
G
--
S
P
A
I
R
D
G
A
N
W
H
A
F
Y
G
S
E
E
S
D
D
L
N
A
R
H
-
V
A
G
D
I
C
S
-
R
F
Y
D
I
N
G
G
L
V
D
T
N
M
S
E
K
--
T
L
S
I
E
M
A
K
L
R
Q
A
R
Y
S
I
G
I
A
M
G
E
E
K
Y
S
G
I
L
G
A
L
H
G
R
-
Y
I
N
C
L
V
T
N
R
E
T
A
E
L
L
L
K
---
25
PsiBlast_PDB
79.29
27%
-85
- C9 -
4L5I
-
LSRR_ECOLI
A:
[16-318]
----
E
E
E
Q
V
A
R
I
A
W
F
Y
Y
H
D
G
L
T
Q
S
E
I
S
D
R
L
G
L
T
R
L
K
V
S
R
L
L
E
K
G
H
Q
S
G
I
I
R
V
Q
I
N
S
R
F
E
G
C
L
E
Y
E
T
Q
L
R
R
Q
F
S
L
Q
H
V
R
V
I
P
--
G
L
A
-
D
A
D
V
G
G
R
L
G
I
G
A
A
H
M
L
M
S
L
L
Q
P
Q
-
Q
M
L
A
I
G
F
G
E
A
T
M
N
T
L
Q
R
L
S
-
G
F
I
S
--
S
-
Q
Q
I
R
L
V
T
L
S
G
G
-
V
G
-
S
Y
-
M
T
G
I
-
G
--------
Q
L
N
A
A
C
S
V
N
I
I
P
A
P
L
R
A
S
S
A
D
I
A
R
T
L
K
N
E
N
C
V
K
D
V
L
L
A
A
Q
A
A
D
V
A
I
V
G
I
G
A
V
S
Q
Q
D
D
A
T
I
I
R
S
G
Y
I
S
Q
G
E
Q
L
M
I
G
R
K
G
-
A
V
G
D
I
L
G
-
Y
F
F
D
A
K
G
-
D
V
V
T
N
I
K
I
H
N
E
L
I
G
L
P
L
S
A
L
K
T
I
P
V
R
V
G
V
A
G
G
E
N
K
A
E
A
I
A
A
A
M
K
G
G
-
Y
I
N
A
L
V
T
D
Q
D
T
A
A
A
I
L
R
S
--
26
PsiBlast_PDB
78.96
27%
-82
- C9 -
4L5J
1
LSRR_ECOLI
A:
[16-318]
----
E
E
E
Q
V
A
R
I
A
W
F
Y
Y
H
D
G
L
T
Q
S
E
I
S
D
R
L
G
L
T
R
L
K
V
S
R
L
L
E
K
G
H
Q
S
G
I
I
R
V
Q
I
N
S
R
F
E
G
C
L
E
Y
E
T
Q
L
R
R
Q
F
S
L
Q
H
V
R
V
I
P
--
G
L
A
-
D
A
D
V
G
G
R
L
G
I
G
A
A
H
M
L
M
S
L
L
Q
P
Q
-
Q
M
L
A
I
G
F
G
E
A
T
M
N
T
L
Q
R
L
S
-
G
F
I
S
--
S
-
Q
Q
I
R
L
V
T
L
S
G
G
-
V
G
-
S
Y
-
M
T
G
I
-
G
--------
Q
L
N
A
A
C
S
V
N
I
I
P
A
P
L
R
A
S
S
A
D
I
A
R
T
L
K
N
E
N
C
V
K
D
V
L
L
A
A
Q
A
A
D
V
A
I
V
G
I
G
A
V
S
Q
Q
D
D
A
T
I
I
R
S
G
Y
I
S
Q
G
E
Q
L
M
I
G
R
K
G
-
A
V
G
D
I
L
G
-
Y
F
F
D
A
K
G
-
D
V
V
T
N
I
K
I
H
N
E
L
I
G
L
P
L
S
A
L
K
T
I
P
V
R
V
G
V
A
G
G
E
N
K
A
E
A
I
A
A
A
M
K
G
G
-
Y
I
N
A
L
V
T
D
Q
D
T
A
A
A
I
L
R
S
--
27
PsiBlast_PDB
76.71
27%
-82
- C9 -
4GO1
1
LSRR_ECOLI
A:
[15-317]
----
E
E
E
Q
V
A
R
I
A
W
F
Y
Y
H
D
G
L
T
Q
S
E
I
S
D
R
L
G
L
T
R
L
K
V
S
R
L
L
E
K
G
H
Q
S
G
I
I
R
V
Q
I
N
S
R
F
E
G
C
L
E
Y
E
T
Q
L
R
R
Q
F
S
L
Q
H
V
R
V
I
P
--
G
L
A
-
D
A
D
V
G
G
R
L
G
I
G
A
A
H
M
L
M
S
L
L
Q
P
Q
-
Q
M
L
A
I
G
F
G
E
A
T
M
N
T
L
Q
R
L
S
-
G
F
I
S
--
S
-
Q
Q
I
R
L
V
T
L
S
G
G
-
V
G
-
S
Y
-
M
T
G
I
-
G
--------
Q
L
N
A
A
C
S
V
N
I
I
P
A
P
L
R
A
S
S
A
D
I
A
R
T
L
K
N
E
N
C
V
K
D
V
L
L
A
A
Q
A
A
D
V
A
I
V
G
I
G
A
V
S
Q
--------------
G
E
Q
L
M
I
G
R
K
G
-
A
V
G
D
I
L
G
-
Y
F
F
D
A
K
G
-
D
V
V
T
N
I
K
I
H
N
E
L
I
G
L
P
L
S
A
L
K
T
I
P
V
R
V
G
V
A
G
G
E
N
K
A
E
A
I
A
A
A
M
K
G
G
-
Y
I
N
A
L
V
T
D
Q
D
T
A
A
A
I
L
R
S
--
24
PsiBlast_PDB
76.30
30%
-88
- C9 -
3KV1
5
?
A:
[9-260]
------------------------------------------------------------
S
V
Q
L
E
Q
K
L
V
E
K
F
N
L
K
R
A
L
I
S
L
D
Q
P
N
T
-
N
E
Q
R
K
Q
V
A
A
L
V
S
S
Y
-
L
N
N
N
L
Q
E
G
-
M
A
V
A
V
G
Q
G
Q
-
N
V
A
A
V
A
D
H
A
-
G
I
V
T
--
Q
-
R
N
A
R
F
V
S
A
I
G
G
-
T
H
------
I
I
-
N
A
D
H
I
C
R
R
L
A
K
K
Y
G
G
S
S
E
T
L
Y
A
P
A
Y
V
N
D
P
S
L
R
S
A
F
M
E
H
A
T
I
K
E
T
L
S
Q
A
R
K
A
E
F
A
L
V
G
I
G
--
D
M
D
E
N
S
H
M
V
K
L
G
F
F
T
P
K
E
F
V
E
A
R
L
N
D
G
I
V
G
D
I
G
G
F
D
F
F
K
L
D
G
T
D
A
D
T
L
M
R
G
R
--
V
I
G
L
E
M
E
D
L
R
Q
I
P
N
V
V
A
M
A
S
E
S
R
K
A
L
S
I
M
G
A
L
R
T
G
-
V
I
D
V
L
A
T
S
V
S
C
A
M
A
L
L
----
28
PsiBlast_PDB
76.00
25%
-100
- C9 -
3EFB
-
?
A:
[16-266]
---------------------------------------------------------------
L
E
Q
Q
L
K
Q
K
F
G
L
K
D
V
V
V
V
S
G
N
D
E
D
-
E
E
T
Q
L
A
M
M
G
L
H
G
A
Q
L
L
D
R
L
L
E
P
G
-
D
I
V
G
F
S
W
G
R
-
A
V
S
A
L
V
E
N
L
-
P
Q
A
G
--
Q
S
R
Q
L
I
C
V
P
I
I
G
G
P
S
G
-
K
L
-
E
S
R
Y
-
H
V
N
T
L
T
Y
S
A
A
A
K
L
K
G
E
S
H
L
A
D
F
P
A
L
L
D
N
P
L
I
R
N
G
I
M
Q
S
Q
H
F
K
T
I
S
A
Y
W
D
N
L
D
I
A
L
V
G
I
G
--
S
P
---------
A
F
Y
G
G
E
E
S
D
D
L
N
A
R
Q
-
V
A
G
D
I
C
S
-
R
F
F
D
I
H
G
A
M
V
E
T
N
M
S
E
K
--
T
L
S
I
E
M
N
K
L
K
Q
A
R
Y
S
I
G
I
A
M
S
E
E
K
Y
S
G
I
I
G
A
L
R
G
K
-
Y
I
N
C
L
V
T
N
S
S
T
A
E
L
L
L
K
---
29
PsiBlast_PDB
75.63
26%
-97
- C9 -
4OQP
7
DEOR_BACSU
A:
[19-261]
-------------------------------------------------------------------
L
E
E
K
Y
G
L
L
E
A
H
V
V
F
S
P
T
P
D
-
Y
A
G
I
T
H
D
L
S
R
Y
G
A
E
Y
M
H
E
T
V
K
D
G
-
D
I
V
G
V
S
W
G
T
-
T
M
Y
Q
I
A
Q
N
M
-
Q
P
K
Q
--
V
-
K
G
V
E
V
V
Q
L
K
G
G
-
I
S
-
H
S
-
R
V
N
T
-
Y
S
A
E
T
I
Q
L
F
A
E
A
F
Q
T
M
P
R
Y
L
P
L
P
V
V
F
D
N
A
D
V
K
R
M
V
E
K
D
R
H
I
E
R
I
I
E
M
G
K
Q
A
N
I
A
L
F
T
V
G
--
T
V
R
D
E
A
L
L
F
R
L
G
Y
F
N
E
E
E
-
K
A
L
L
K
K
Q
-
A
V
G
D
I
C
S
-
R
F
F
D
A
K
G
N
I
C
S
S
A
I
N
D
R
--
T
I
G
V
E
L
Q
D
L
R
L
K
E
R
S
I
L
V
A
G
G
S
R
K
V
S
S
I
H
G
A
L
T
G
K
-
Y
A
N
V
L
I
I
D
Q
H
T
A
R
A
L
V
----
2
HHSearch
75.38
25%
-100
- C9 -
3EFB
-
?
A:
[12-266]
-----------------------------------------------------------
E
N
L
W
L
E
Q
Q
L
K
Q
K
F
G
L
K
D
V
V
V
V
S
G
N
D
E
D
-
E
E
T
Q
L
A
M
M
G
L
H
G
A
Q
L
L
D
R
L
L
E
P
G
-
D
I
V
G
F
S
W
G
R
-
A
V
S
A
L
V
E
N
L
-
P
Q
A
G
Q-
S
-
R
Q
L
I
C
V
P
I
I
G
G
-
P
S
-
G
K
L
E
S
R
Y
-
H
V
N
T
L
T
Y
S
A
A
A
K
L
K
G
E
S
H
L
A
D
F
P
A
L
L
D
N
P
L
I
R
N
G
I
M
Q
S
Q
H
F
K
T
I
S
A
Y
W
D
N
L
D
I
A
L
V
G
I
G
--
S
P
---------
A
F
Y
G
G
E
E
S
D
D
L
N
A
R
Q
-
V
A
G
D
I
C
S
-
R
F
F
D
I
H
G
A
M
V
E
T
N
M
S
E
K
--
T
L
S
I
E
M
N
K
L
K
Q
A
R
Y
S
I
G
I
A
M
S
E
E
K
Y
S
G
I
I
G
A
L
R
G
K
-
Y
I
N
C
L
V
T
N
S
S
T
A
E
L
L
L
K
---
30
PsiBlast_PDB
75.04
26%
-96
- C9 -
4OQQ
1
DEOR_BACSU
A:
[19-261]
-------------------------------------------------------------------
L
E
E
K
Y
G
L
L
E
A
H
V
V
F
S
P
T
P
D
-
Y
A
G
I
T
H
D
L
S
R
Y
G
A
E
Y
M
H
E
T
V
K
D
G
-
D
I
V
G
V
S
W
G
T
-
T
M
Y
Q
I
A
Q
N
M
-
Q
P
K
Q
--
V
-
K
G
V
E
V
V
Q
L
K
G
G
-
I
S
-
H
S
-
R
V
N
T
-
Y
S
A
E
T
I
Q
L
F
A
E
A
F
Q
T
M
P
R
Y
L
P
L
P
V
V
F
D
N
A
D
V
K
R
M
V
E
K
D
R
H
I
E
R
I
I
E
M
G
K
Q
A
N
I
A
L
F
T
V
G
--
T
V
R
D
E
A
L
L
F
R
L
G
Y
F
N
E
E
E
-
K
A
L
L
K
K
Q
-
A
V
G
D
I
C
S
-
R
F
F
D
A
K
G
N
I
C
S
S
A
I
N
D
R
--
T
I
G
V
E
L
Q
D
L
R
L
K
E
R
S
I
L
V
A
G
G
S
R
K
V
S
S
I
H
G
A
L
T
G
K
-
Y
A
N
V
L
I
I
D
Q
H
T
A
R
A
L
V
----
33
PsiBlast_PDB
74.35
26%
-82
- C9 -
4L4Z
1
LSRR_ECOLI
A:
[18-266]
----------------------------------------------------------
E
G
C
L
E
Y
E
T
Q
L
R
R
Q
F
S
L
Q
H
V
R
V
I
P
--
G
L
A
-
D
A
D
V
G
G
R
L
G
I
G
A
A
H
M
L
M
S
L
L
Q
P
Q
-
Q
M
L
A
I
G
F
G
E
A
T
M
N
T
L
Q
R
L
S
-
G
F
I
S
--
S
-
Q
Q
I
R
L
V
T
L
S
G
G
-
V
G
-
S
Y
-
M
T
G
I
-
G
--------
Q
L
N
A
A
C
S
V
N
I
I
P
A
P
L
R
A
S
S
A
D
I
A
R
T
L
K
N
E
N
C
V
K
D
V
L
L
A
A
Q
A
A
D
V
A
I
V
G
I
G
A
V
S
Q
Q
D
D
A
T
I
I
R
S
G
Y
I
S
Q
G
E
Q
L
M
I
G
R
K
G
-
A
V
G
D
I
L
G
-
Y
F
F
D
A
K
G
-
D
V
V
T
N
I
K
I
H
N
E
L
I
G
L
P
L
S
A
L
K
T
I
P
V
R
V
G
V
A
G
G
E
N
K
A
E
A
I
A
A
A
M
K
G
G
-
Y
I
N
A
L
V
T
D
Q
D
T
A
A
A
I
L
R
S
--
3
HHSearch
73.85
24%
-86
- C9 -
2GNP
1
?
A:
[9-263]
------------------------------------------------------------
M
F
K
L
E
N
Y
V
K
E
K
Y
S
L
E
S
L
E
I
I
P
N
E
F
D
D
T
P
T
I
L
S
E
R
I
S
Q
V
A
A
G
V
L
R
N
L
I
D
D
N
-
M
K
I
G
F
S
W
G
K
-
S
L
S
N
L
V
D
L
I
-
H
S
K
S
--
V
-
R
N
V
H
F
Y
P
L
A
G
G
-
P
S
-
H
I
-
H
A
K
Y
-
H
V
N
T
L
I
Y
E
M
S
R
K
F
H
G
E
C
T
F
M
N
A
T
I
V
Q
E
N
K
L
L
A
D
G
I
L
Q
S
R
Y
F
E
N
L
K
N
S
W
K
D
L
D
I
A
V
V
G
I
G
--
D
F
S
N
K
G
K
H
Q
W
L
D
M
L
T
E
D
D
F
K
E
L
T
K
V
K
-
T
V
G
E
I
C
C
-
R
F
F
D
S
K
G
K
E
V
Y
E
N
L
Q
E
R
--
T
I
A
I
S
L
E
D
L
K
N
I
P
Q
S
L
A
V
A
Y
G
D
T
K
V
S
S
I
L
S
V
L
R
A
N
-
L
V
N
H
L
I
T
D
K
N
T
I
L
K
V
L
E
E
D
-
34
PsiBlast_PDB
73.35
26%
-86
- C9 -
4L50
1
LSRR_ECOLI
A:
[17-266]
---------------------------------------------------------
F
E
G
C
L
E
Y
E
T
Q
L
R
R
Q
F
S
L
Q
H
V
R
V
I
P
--
G
L
A
-
D
--
V
G
G
R
L
G
I
G
A
A
H
M
L
M
S
L
L
Q
P
Q
-
Q
M
L
A
I
G
F
G
E
A
T
M
N
T
L
Q
R
L
S
-
G
F
I
S
--
S
-
Q
Q
I
R
L
V
T
L
S
G
G
-
V
G
-
S
Y
-
M
T
G
I
-
G
--------
Q
L
N
A
A
C
S
V
N
I
I
P
A
P
L
R
A
S
S
A
D
I
A
R
T
L
K
N
E
N
C
V
K
D
V
L
L
A
A
Q
A
A
D
V
A
I
V
G
I
G
A
V
S
Q
Q
D
D
A
T
I
I
R
S
G
Y
I
S
Q
G
E
Q
L
M
I
G
R
K
G
-
A
V
G
D
I
L
G
-
Y
F
F
D
A
K
G
-
D
V
V
T
N
I
K
I
H
N
E
L
I
G
L
P
L
S
A
L
K
T
I
P
V
R
V
G
V
A
G
G
E
N
K
A
E
A
I
A
A
A
M
K
G
G
-
Y
I
N
A
L
V
T
D
Q
D
T
A
A
A
I
L
R
S
--
4
HHSearch
72.94
24%
-95
- C9 -
3NZE
-
?
A:
[9-263]
------------------------------------------------------------
G
P
E
L
E
S
Q
I
R
N
Q
Y
G
V
-
D
V
H
V
V
P
V
L
D
T
L
N
E
A
E
T
L
D
R
V
A
M
Q
A
A
R
T
I
G
P
L
V
D
S
N
-
A
I
I
G
V
A
W
G
A
-
T
L
S
A
V
S
R
H
L
-
T
R
K
M
--
T
-
H
D
S
I
V
V
Q
L
N
G
A
-
G
N
-
M
Q
T
T
G
I
T
-
Y
A
S
D
I
M
R
R
F
G
S
A
Y
G
A
R
V
E
Q
F
P
V
P
A
F
F
D
H
A
S
T
K
T
A
M
W
N
E
R
S
V
Q
R
I
L
D
L
Q
A
R
M
S
I
A
I
F
G
V
G
--
S
V
D
---
H
V
Y
A
G
G
Y
L
D
E
H
D
L
T
M
L
A
A
D
D
-
V
V
G
D
V
A
T
-
V
F
F
R
S
D
G
S
S
D
G
I
T
L
N
E
R
--
S
T
G
P
S
H
E
Q
L
R
Q
V
R
R
R
I
C
V
V
S
G
A
S
K
I
N
G
L
Q
G
A
L
A
A
G
-
L
A
T
D
L
I
L
D
E
A
S
A
R
R
L
V
S
---
36
PsiBlast_PDB
72.93
22%
-95
- C9 -
3NZE
-
?
A:
[11-263]
--------------------------------------------------------------
E
L
E
S
Q
I
R
N
Q
Y
G
V
D
V
H
V
V
P
V
L
D
T
L
N
-
E
A
E
T
L
D
R
V
A
M
Q
A
A
R
T
I
G
P
L
V
D
S
N
-
A
I
I
G
V
A
W
G
A
-
T
L
S
A
V
S
R
H
L
-
T
R
K
M
--
T
-
H
D
S
I
V
V
Q
L
N
G
A
-
G
N
-
M
Q
-
T
T
G
I
T
Y
A
S
D
I
M
R
R
F
G
S
A
Y
G
A
R
V
E
Q
F
P
V
P
A
F
F
D
H
A
S
T
K
T
A
M
W
N
E
R
S
V
Q
R
I
L
D
L
Q
A
R
M
S
I
A
I
F
G
V
G
--
S
V
D
---
H
V
Y
A
G
G
Y
L
D
E
H
D
L
T
M
L
A
A
D
D
-
V
V
G
D
V
A
T
-
V
F
F
R
S
D
G
S
S
D
G
I
T
L
N
E
R
--
S
T
G
P
S
H
E
Q
L
R
Q
V
R
R
R
I
C
V
V
S
G
A
S
K
I
N
G
L
Q
G
A
L
A
A
G
-
L
A
T
D
L
I
L
D
E
A
S
A
R
R
L
V
S
---
5
HHSearch
71.89
20%
-75
- C9 -
2O0M
2
?
A:
[95-341]
-------------------------------------------------------------
H
Q
I
E
K
E
M
T
Q
Y
F
G
I
Q
R
C
I
V
V
A
G
D
S
D
I
-
Q
K
K
V
L
S
D
F
G
D
V
L
T
N
T
L
N
L
L
L
P
N
G
E
N
T
I
A
V
M
G
G
T
-
T
M
A
M
V
A
E
N
M
-
G
S
L
E
TE
K
-
R
H
N
L
F
V
P
A
R
G
G
-
I
G
-
E
A
-
V
-
S
V
-
Q
A
N
S
I
S
A
V
M
A
N
K
T
G
G
N
Y
R
A
L
Y
V
P
E
Q
L
S
-
R
E
T
Y
N
S
L
L
Q
E
P
S
I
Q
E
V
L
T
L
I
S
H
A
N
C
V
V
H
S
I
G
--
R
A
L
H
M
---
A
A
R
R
K
M
S
D
D
E
M
V
M
L
K
Q
K
N
-
A
V
A
E
S
F
G
-
Y
F
F
D
E
E
G
K
V
V
Y
K
---
I
P
--
R
I
G
L
Q
L
K
N
L
Q
E
I
P
Y
V
V
A
I
A
G
G
K
T
K
A
K
A
I
R
A
Y
M
K
N
A
P
K
Q
T
W
L
I
T
D
E
A
A
A
N
E
I
L
K
---
40
PsiBlast_PDB
71.70
24%
-80
- C9 -
3BXH
2
CGGR_BACSU
A:
[12-253]
---------------------------------------------------------------
L
E
K
T
L
K
E
R
L
N
L
K
D
A
I
I
V
S
G
D
S
D
Q
-
S
P
W
V
K
K
E
M
G
R
A
A
V
A
C
M
K
K
R
F
S
G
K
-
N
I
V
A
V
T
G
G
T
-
T
I
E
A
V
A
E
M
M
T
P
D
S
K
--
N
-
R
E
L
L
F
V
P
A
R
G
G
-
L
G
-
E
--
D
V
K
N
-
Q
A
N
T
I
C
A
H
M
A
E
K
A
S
G
T
Y
R
L
L
F
V
P
G
Q
L
S
Q
G
A
Y
-
S
S
I
I
E
E
P
S
V
K
E
V
L
N
T
I
K
S
A
S
M
L
V
H
G
I
G
--
E
A
---
K
T
M
A
Q
R
R
N
T
P
L
E
D
L
K
K
I
D
D
N
D
-
A
V
T
E
A
F
G
-
Y
Y
F
N
A
D
G
E
V
V
H
---
K
V
H
--
S
V
G
M
Q
L
D
D
I
D
A
I
P
D
I
I
A
V
A
G
G
S
S
K
A
E
A
I
E
A
Y
F
K
K
P
-
R
N
T
V
L
V
T
D
E
G
A
A
K
K
L
L
R
---
35
PsiBlast_PDB
71.42
26%
-81
- C9 -
4L51
1
LSRR_ECOLI
A:
[18-266]
----------------------------------------------------------
E
G
C
L
E
Y
E
T
Q
L
R
R
Q
F
S
L
Q
H
V
R
V
I
P
--
G
L
----
D
V
G
G
R
L
G
I
G
A
A
H
M
L
M
S
L
L
Q
P
Q
-
Q
M
L
A
I
G
F
G
E
A
T
M
N
T
L
Q
R
L
S
-
G
F
I
S
--
S
-
Q
Q
I
R
L
V
T
L
S
G
G
-
V
G
-
S
Y
-
M
T
G
I
-
G
--------
Q
L
N
A
A
C
S
V
N
I
I
P
A
P
L
R
A
S
S
A
D
I
A
R
T
L
K
N
E
N
C
V
K
D
V
L
L
A
A
Q
A
A
D
V
A
I
V
G
I
G
A
V
S
Q
Q
D
D
A
T
I
I
R
S
G
Y
I
S
Q
G
E
Q
L
M
I
G
R
K
G
-
A
V
G
D
I
L
G
-
Y
F
F
D
A
K
G
-
D
V
V
T
N
I
K
I
H
N
E
L
I
G
L
P
L
S
A
L
K
T
I
P
V
R
V
G
V
A
G
G
E
N
K
A
E
A
I
A
A
A
M
K
G
G
-
Y
I
N
A
L
V
T
D
Q
D
T
A
A
A
I
L
R
S
--