@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1104: (2016-03-21 )
MKLVKYFAIFGVVFSMFFSLLLFVTIVFAEEDDTRSSREEMIQQGGLNVSAEVLAHRPMVEKYCKEFGIEEYVNYILAIMQVESGGTAEDVMQSSESLGLPPNSLSTEESIKQGCKYFSELLASAESNGCDINTVIQSYNYGGGFINYVASNGKKYSYELAESFSKDKAGGVKVDYPNPIAIPVNGGWRYNYGNQFYVLLVSQYLTPVQFDDETVQAIMNEALKYEGYPYVFGGSSPSTSFDCSGLTQWSYAVAGIQLPRVAQAQYDATQHIPLSEAKAGDLVFFHSTYDAGSYVTHVGIYVGNNQMYHAGDPIGYTNLTDSYWQAHLIGAGRIIK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........-80........90.-.......100.......110.......120.......130.......140.......150.......160---.........170.......180.......190.......200...--.---...210.......-220..-.....230..---..---.------------.---------.240....-...250.-.-.....260.......270.......280.......290.......300.......310-----.------.------...--...320------........330....-------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
L
V
K
Y
F
A
I
F
G
V
V
F
S
M
F
F
S
L
L
L
F
V
T
I
V
F
AEEDDT
R
S
S
R
E
E
M
I
Q
QGGL
N
V
S
A
E
V
L
AH
R
P
M
V
E
K
Y
C
K
EF
G
I
E
E
Y
V
N
Y
I
L
A
I
-
M
QVESGG
T
A
E
D
V
M
-
Q
S
S
E
SLGLPPNSLS
T
E
E
S
I
K
Q
G
C
K
Y
F
S
E
L
L
A
SAESNGC
D
I
N
T
V
I
Q
SYNYGG
G
F
I
N
Y
VASNGK
K
Y
S
Y
E
L
-----
A
E
SFSKDKAG
G
V
K
V
DYPN
P
I
A
I
PVNG
G
W
RYNYG
N
Q
F
Y
V
L
L
V
S
Q
YL--T---PVQF
D
D
E
T
V
Q
A
I
M
-
N
E
A
LK-YEGY
P
Y
V
FGG---SS---P------------S---------TSFDCSGL-TQ
W
S
Y
A
V-A-GIQLP
R
V
A
Q
AQYDATQHIPLSEAKAG
D
L
V
F
F
HSTYDAGS
Y
V
T
H
V
G
I
Y
VGNN
Q
M
Y
HAG------D------P------IGY--TNL
T
D
-------
S
Y
W
Q
A
H
LIGAGRIIK-------
1
PsiBlast_PDB
72.25
74%
-2
- C2 -
4FDY
-
?
A:
[46-338]
---------------------------------------------
G
V
T
V
S
P
E
V
L
A
H
R
P
L
I
E
K
Y
G
K
E
Y
G
I
E
D
Y
V
S
Y
I
L
A
I
-
M
Q
V
E
S
G
G
T
A
E
D
V
M
-
Q
S
S
E
S
L
G
L
P
P
N
S
L
S
T
E
E
S
I
K
Q
G
V
K
Y
F
S
E
L
L
T
S
A
E
Q
Q
G
V
D
I
D
S
V
I
Q
S
Y
N
Y
G
G
G
F
L
N
Y
V
R
S
H
G
K
K
Y
T
Y
E
L
-----
A
E
Q
F
S
K
E
K
S
G
G
Q
K
A
D
Y
P
N
P
I
A
I
P
V
N
G
G
W
R
Y
N
Y
G
N
Q
F
Y
V
Q
L
V
S
Q
Y
L
--
T
DTS
P
T
E
F
D
D
E
T
V
Q
V
I
M
-
D
E
A
L
K
-
Y
E
G
F
P
Y
V
F
G
G
---
A
S
---
P
------------
T
---------
T
S
F
D
-
S
G
L
-
I
Q
W
V
Y
D
K
-
A
-
G
I
S
L
P
R
V
A
Q
D
Q
Y
D
A
T
Q
E
I
S
M
E
E
A
Q
A
G
D
L
I
F
F
H
S
T
Y
N
A
G
T
Y
V
T
H
V
A
I
Y
L
E
G
N
R
F
Y
H
A
G
------
D
------
P
------
I
G
Y
--
G
D
L
S
S
-------
R
Y
W
Q
D
H
L
I
G
A
R
R
V
I
--------
45
Fugue
69.71
73%
-8
- C2 -
4FDY
-
?
A:
[46-340]
---------------------------------------------
G
V
T
V
S
P
E
V
L
A
H
R
P
L
I
E
K
Y
G
K
E
Y
G
I
E
D
Y
V
S
Y
I
L
A
I
M
Q
V
-
E
S
G
G
T
A
E
D
-
V
M
Q
S
S
E
S
L
G
L
P
P
N
S
L
S
T
E
E
S
I
K
Q
G
V
K
Y
F
S
E
L
L
T
S
A
E
Q
Q
G
V
D
I
D
S
V
I
Q
S
Y
N
Y
G
G
G
F
L
N
Y
V
R
S
H
G
K
K
Y
T
Y
E
L
-----
A
E
Q
F
S
K
E
K
S
G
G
Q
K
A
D
Y
P
N
P
I
A
I
P
V
N
G
G
W
R
Y
N
Y
G
N
Q
F
Y
V
Q
L
V
S
Q
Y
L
TD
T
---
S
P
T
E
F
D
D
E
T
V
Q
V
I
M
D
E
A
L
K
-
Y
E
G
F
P
Y
V
F
G
G
---
A
S
---
P
------------
T
---------
T
-
S
F
D
S
G
L
-
I
Q
W
V
Y
D
K
-
A
-
G
I
S
L
P
R
V
A
Q
D
Q
Y
D
A
T
Q
E
I
S
M
E
E
A
Q
A
G
D
L
I
F
F
H
S
T
Y
N
A
G
T
Y
V
T
H
V
A
I
Y
L
E
G
N
R
F
Y
H
A
G
------
D
------
P
------
I
G
Y
--
G
D
L
S
S
-------
R
Y
W
Q
D
H
L
I
G
A
R
R
V
I
H
N------
7
PsiBlast_PDB
64.23
38%
-100
- C2 -
2FG0
2
?
A:
[112-239]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
A
F
T
-
Q
K
A
M
Q
-
Q
S
N
Y
-
Y
L
W
G
G
---
T
V
----------------
G
---------
P
N
Y
D
C
S
G
L
-
M
Q
A
A
F
A
S
-
V
-
G
I
W
L
P
R
D
A
Y
Q
Q
E
G
F
T
Q
P
I
T
I
A
E
L
V
A
G
D
L
V
F
F
G
T
S
Q
K
A
----
T
H
V
G
L
Y
L
A
D
G
Y
Y
I
H
S
S
G
KDQGR
D
------
G
------
I
G
I
--
D
I
L
S
E
QGD
A
V
S
L
S
Y
Y
Q
-
Q
L
R
G
A
G
R
V
F
K
-------
6
PsiBlast_PDB
64.15
38%
-94
- C2 -
2EVR
3
?
A:
[112-239]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
A
F
T
-
Q
K
A
M
Q
-
Q
S
N
Y
-
Y
L
W
G
G
---
T
V
----------------
G
---------
P
N
Y
D
C
S
G
L
-
M
Q
A
A
F
A
S
-
V
-
G
I
W
L
P
R
D
A
Y
Q
Q
E
G
F
T
Q
P
I
T
I
A
E
L
V
A
G
D
L
V
F
F
G
T
S
Q
K
A
----
T
H
V
G
L
Y
L
A
D
G
Y
Y
I
H
S
S
G
KDQGR
D
------
G
------
I
G
I
--
D
I
L
S
E
QGD
A
V
S
L
S
Y
Y
Q
-
Q
L
R
G
A
G
R
V
F
K
-------
26
HHSearch
63.17
41%
-102
- C2 -
2HBW
3
?
A:
[103-228]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
T
-
Q
K
A
M
Q
-
Q
-
S
N
Y
Y
L
W
G
G
---
T
V
---
G
------------
P
----------
N
Y
D
C
S
G
L
-
M
Q
A
A
F
V
S
-
V
-
G
I
W
L
P
R
D
A
Y
Q
Q
E
A
F
T
Q
A
I
T
I
D
E
L
A
P
G
D
L
V
F
F
G
T
P
----
V
K
A
T
H
V
G
L
Y
L
G
D
G
C
Y
I
H
S
S
------
G
KAQGRD
G
------
I
G
I
--
D
I
L
S
E
QGD
V
V
S
R
S
Y
Y
-
Q
Q
L
R
G
A
G
R
V
V
K
-------
8
PsiBlast_PDB
62.35
37%
-96
- C2 -
2HBW
3
?
A:
[103-228]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
T
-
Q
K
A
M
Q
-
Q
S
N
Y
-
Y
L
W
G
G
---
T
V
----------------
G
---------
P
N
Y
D
C
S
G
L
-
M
Q
A
A
F
V
S
-
V
-
G
I
W
L
P
R
D
A
Y
Q
Q
E
A
F
T
Q
A
I
T
I
D
E
L
A
P
G
D
L
V
F
F
G
T
P
V
K
A
----
T
H
V
G
L
Y
L
G
D
G
C
Y
I
H
S
S
G
KAQGR
D
------
G
------
I
G
I
--
D
I
L
S
E
QGD
V
V
S
R
S
Y
Y
Q
-
Q
L
R
G
A
G
R
V
V
K
-------
24
HHSearch
61.42
36%
-108
- C2 -
3PBI
-
RIPB_MYCTU
A:
[110-239]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
V
E
Y
V
I
-
R
R
A
G
S
-
Q
M
G
V
P
Y
S
W
G
G
---
G
S
---
L
QGPSKGVDSGAN
T
---------
V
G
F
D
C
S
G
L
-
V
R
Y
A
F
A
G
-
V
-
G
V
L
I
P
R
F
S
G
D
Q
Y
N
A
G
R
H
V
P
P
A
E
A
K
R
G
D
L
I
F
Y
G
P
G
-----
G
G
Q
H
V
T
L
Y
L
G
N
G
Q
M
L
E
A
S
------
G
SAG---
K
------
V
T
V
--
S
P
V
R
K
-------
A
G
M
---
T
P
F
V
T
R
I
I
--------
22
HHSearch
60.12
33%
-98
- C2 -
2K1G
-
MEPS_ECOLI
A:
[39-159]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
K
S
R
I
M
-
D
Q
Y
A
D
-
W
K
G
V
R
Y
R
L
G
G
---
S
T
---
K
------------
K
----------
G
I
D
C
S
G
F
-
V
Q
R
T
F
R
E
Q
F
-
G
L
E
L
P
R
S
T
Y
E
Q
Q
E
M
G
K
S
V
S
R
S
N
L
R
T
G
D
L
V
L
F
R
A
G
----
S
T
G
R
H
V
G
I
Y
I
G
N
N
Q
F
V
H
A
S
------
T
SS----
G
------
V
I
I
--
S
S
M
N
E
-------
P
Y
W
K
K
R
Y
N
E
A
R
R
V
L
--------
4
PsiBlast_PDB
58.23
35%
-77
- C2 -
3I86
-
?
A:
[7-114]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
G
R
Q
A
I
E
Y
V
I
-
K
R
M
G
S
-
Q
M
G
V
P
Y
S
W
G
G
---
G
S
LDG
P
------------
S
KGVGDGANI
T
G
F
D
C
S
G
L
-
M
R
Y
G
F
A
G
-
V
-
G
V
L
I
P
R
F
S
G
D
Q
Y
N
A
G
R
H
I
P
Q
D
Q
A
R
R
G
D
L
I
F
Y
G
P
---
G
G
S
--
Q
H
V
T
M
Y
L
G
N
G
Q
M
L
E
A
------------------------------------------------------------
21
PsiBlast_CBE
57.11
35%
-68
- C2 -
3I86
1
?
B:
[7-114]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
G
R
Q
A
I
E
Y
V
I
-
K
R
M
G
S
-
Q
M
G
V
P
Y
S
W
G
G
---
G
S
LD
G
P
------------
S
K
G
V
GDGANI
T
G
F
D
C
S
G
L
-
M
R
Y
G
F
A
G
-
V
-
G
V
L
I
P
R
F
S
G
D
Q
Y
N
A
G
R
H
I
P
Q
D
Q
A
R
R
G
D
L
I
F
Y
G
P
---
G
G
S
--
Q
H
V
T
M
Y
L
G
N
G
Q
M
L
E
A
------------------------------------------------------------
2
PsiBlast_PDB
56.82
34%
-98
- C2 -
2K1G
-
MEPS_ECOLI
A:
[44-159]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
M
-
D
Q
Y
A
D
-
W
K
G
V
R
Y
R
L
G
G
---
S
T
---
K
------------
K
----------
G
I
D
C
S
G
F
-
V
Q
R
T
F
R
E
-
Q
F
G
L
E
L
P
R
S
T
Y
E
Q
Q
E
M
G
K
S
V
S
R
S
N
L
R
T
G
D
L
V
L
F
R
----
A
G
S
T
G
R
H
V
G
I
Y
I
G
N
N
Q
F
V
H
A
S
------
T
------
S
------
S
G
V
I
I
S
S
M
N
E
-------
P
Y
W
K
K
R
Y
N
E
A
R
R
V
L
--------
15
PsiBlast_PDB
56.12
32%
-74
- C2 -
4Q4G
-
RIPA_MYCTU
X:
[330-447]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
G
R
--
I
---
P
R
V
Y
G
R
Q
A
S
E
Y
V
I
-
R
R
G
M
S
-
Q
I
G
V
P
Y
S
W
G
G
GNA
A
G
---
P
------------
S
KGIDSGAGT
V
G
F
D
A
S
G
L
-
V
L
Y
S
F
A
G
-
V
-
G
I
K
L
P
H
Y
S
G
S
Q
Y
N
L
G
R
K
I
P
S
S
Q
M
R
R
G
D
V
I
F
Y
G
P
N
---
G
S
Q
--
H
V
T
I
Y
L
G
N
G
Q
M
L
E
A
P
------
D
----------------------------------------------------
10
PsiBlast_PDB
56.09
33%
-71
- C2 -
3PBC
-
RIPA_MYCTU
A:
[330-447]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
G
R
--
I
---
P
R
V
Y
G
R
Q
A
S
E
Y
V
I
-
R
R
G
M
S
-
Q
I
G
V
P
Y
S
W
G
G
G
N
A
A
G
---
P
------------
S
KGIDSGAGT
V
G
F
D
C
S
G
L
-
V
L
Y
S
F
A
G
-
V
-
G
I
K
L
P
H
Y
S
G
S
Q
Y
N
L
G
R
K
I
P
S
S
Q
M
R
R
G
D
V
I
F
Y
G
P
N
---
G
S
--
Q
H
V
T
I
Y
L
G
N
G
Q
M
L
E
A
P
------
D
----------------------------------------------------
12
PsiBlast_PDB
56.01
32%
-71
- C2 -
3S0Q
-
RIPA_MYCTU
A:
[330-447]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
G
R
--
I
---
P
R
V
Y
G
R
Q
A
S
E
Y
V
I
-
R
R
G
M
S
-
Q
I
G
V
P
Y
S
W
G
G
G
N
A
A
G
---
P
------------
S
KGIDSGAG
T
V
G
F
D
A
S
G
L
-
V
L
Y
S
F
A
G
-
V
-
G
I
K
L
P
H
Y
S
G
S
Q
Y
N
L
G
R
K
I
P
S
S
Q
M
R
R
G
D
V
I
F
Y
G
P
N
---
G
S
--
Q
H
V
T
I
Y
L
G
N
G
Q
M
L
E
A
P
------
D
----------------------------------------------------
17
PsiBlast_PDB
55.80
29%
-84
- C2 -
4JXB
5
?
A:
[6-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
I
T
D
V
V
I
-
A
R
G
L
S
-
Q
R
G
V
P
F
S
W
A
G
GGI
S
G
---
P
------------
T
RGTGTGINT
V
G
F
D
A
S
G
L
-
I
Q
Y
A
Y
A
G
-
A
-
G
L
K
L
P
R
S
S
G
Q
M
Y
K
V
G
Q
K
V
L
P
Q
Q
A
R
K
G
D
L
I
F
Y
G
P
-----
E
G
T
Q
S
V
A
L
Y
L
G
K
G
Q
M
L
E
V
G
------
D
----------------------------------------------------
9
PsiBlast_PDB
55.75
33%
-72
- C2 -
3NE0
-
A:
[1068-1185]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
G
R
--
I
---
P
R
V
Y
G
R
Q
A
S
E
Y
V
I
-
R
R
G
M
S
-
Q
I
G
V
P
Y
S
W
G
G
G
N
A
A
G
---
P
------------
S
KGIDSGAG
T
V
G
F
D
C
S
G
L
-
V
L
Y
S
F
A
G
-
V
-
G
I
K
L
P
H
Y
S
G
S
Q
Y
N
L
G
R
K
I
P
S
S
Q
M
R
R
G
D
V
I
F
Y
G
P
N
---
G
S
--
Q
H
V
T
I
Y
L
G
N
G
Q
M
L
E
A
P
------
D
----------------------------------------------------
14
PsiBlast_PDB
55.55
32%
-80
- C2 -
4Q4N
-
RIPA_MYCTU
A:
[330-447]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
G
R
--
I
---
P
R
V
Y
G
R
Q
A
S
E
Y
V
I
-
R
R
G
M
S
-
Q
I
G
V
P
Y
S
W
G
G
GNA
A
G
---
P
------------
S
KGIDSGAG
T
V
G
F
D
C
S
G
L
-
V
L
Y
S
F
A
G
-
V
-
G
I
K
L
P
H
Y
S
G
S
Q
Y
N
L
G
R
K
I
P
S
S
Q
M
R
R
G
D
V
I
F
Y
G
P
N
---
G
S
Q
A
--
V
T
I
Y
L
G
N
G
Q
M
L
E
A
P
------
D
----------------------------------------------------
11
PsiBlast_PDB
55.42
33%
-72
- C2 -
4Q4T
4
RIPA_MYCTU
A:
[330-447]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
G
R
--
I
---
P
R
V
Y
G
R
Q
A
S
E
Y
V
I
-
R
R
G
M
S
-
Q
I
G
V
P
Y
S
W
G
G
G
N
A
A
G
---
P
------------
S
KGIDSGAG
T
V
G
F
D
C
S
G
L
-
V
L
Y
S
F
A
G
-
V
-
G
I
K
L
P
H
Y
S
G
S
Q
Y
N
L
G
R
K
I
P
S
S
Q
M
R
R
G
D
V
I
F
Y
G
P
N
---
G
S
Q
--
H
V
T
I
Y
L
G
N
G
Q
M
L
A
A
P
------
D
----------------------------------------------------
47
Fugue
55.24
24%
-57
- C2 -
2EVR
7
?
A:
[25-246]
----------------------------------------------------------------------------------------------------------------------------------------
K
L
G
E
Y
Q
C
L
A
D
L
N
L
F
D
S
P
E
C
T
R
L
A
T
Q
S
A
SG
R
H
L
W
V
T
S
N
H
Q
N
L
A
V
E
V
Y
L
C
E
D
D
Y
P
G
W
L
S
L
S
D
F
D
S
L
Q
P
A
T
V
P
Y
Q
A
A
T
F
--
S
---
E
S
E
I
K
K
L
L
A
E
V
I
A
-
F
T
Q
K
A
M
Q
Q
S
N
Y
Y
L
W
G
G
---
T
V
---
G
------------
P
----------
N
Y
D
C
S
G
L
M
Q
-
A
A
F
A
S
-
V
-
G
I
W
L
P
R
D
A
Y
Q
Q
E
G
F
T
Q
P
I
T
I
A
E
L
V
A
G
D
L
V
F
F
G
T
----
S
Q
K
A
T
H
V
G
L
Y
L
A
D
G
Y
Y
I
H
S
S
------
G
------
K
DQGRD
G
I
G
I
--
D
I
L
S
E
QGD
A
V
S
-
L
S
Y
Y
Q
Q
L
R
G
A
G
R
V
F
K
S
Y
E
P
Q
RR
3
PsiBlast_PDB
54.70
36%
-83
- C2 -
3PBI
-
RIPB_MYCTU
A:
[110-214]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
V
E
Y
V
I
-
R
R
A
G
S
-
Q
M
G
V
P
Y
S
W
G
G
---
G
S
LQG
P
------------
S
KGVDSGAN
T
V
G
F
D
C
S
G
L
-
V
R
Y
A
F
A
G
-
V
-
G
V
L
I
P
R
F
S
G
D
Q
Y
N
A
G
R
H
V
P
P
A
E
A
K
R
G
D
L
I
F
Y
G
P
G
G
G
-----
Q
H
V
T
L
Y
L
G
N
G
Q
M
L
E
A
------------------------------------------------------------