@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1582: (2016-03-26 )
LANEATQELFQVLDNTAIILQNELEISYLEAVYETGENLFQKEVLQKEELSSEKQLKLQESYESIELENFSNEEIRKGLQLALLKGMKHGIQVNHQMTPDSIGFIVAYLLEKVIQKKKNISILDPACGTANLLTTVINQLELKGDVDVHASGVDVDDLLISLALVGADLQRQKMTLLHQDGLANLLVDPVDVVISDLPVGYYPDDENAKTFELCREEGHSFAHFLFIEQGMRYTKPGGYLFFLVPDAMFGTSDFAKVDKFIKKNGHIEGIIKLPETLFKSEQARKSILILRKADVNVKPPKEVLLANLSSLTDPSVTAPILAEIENWFKSKQ
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------......-------...10....-....20........30...-..------...40......----..50........60...-.....70..-.......----------80........-90........100.......110.....--..120.......130.......140------....--------..-...150.......160....----.------..170-----..-...--..-.180..-.---------------------.-----.-----..----------------190...-...---------.200-----..-------..-...---------.210...--...---------..220.....-..230.----..-------.-------...240.-....-..-250.-.......260-.......270....-...280........290.......300----........310----.-------.......320.......330-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LA
N
E
A
T
-------
Q
E
L
F
Q
V
LDN-
T
A
I
I
L
QNEL
E
I
S
Y
L
E
A
V
Y
E
-
T
G
------
E
N
L
F
Q
K
E
V
L
Q
K
----
E
ELS
S
E
K
Q
L
K
L
Q
E
S
Y
E
S-IELENF-
S
N
-
E
E
I
R
K
G
L
----------
Q
L
A
L
L
K
G
M
K
H
-G
I
Q
V
NHQMT
P
D
S
I
G
F
I
V
A
Y
L
L
E
K
V
I
Q
KK--KN
I
S
I
LDPACG
T
A
N
L
L
T
T
V
I
N
Q
L--------ELKG--------D
V
-
D
V
HASGV
D
V
D
D
L
L
I
S
L
A
L
VG----A------
D
L
Q
R
------
Q
K
-
M
T
L
--
L
H
-QDG
L
A
N
-L---------------------L-----V-----D
P
----------------
V
D
V
V
I
S-DLP---------VGY------YP-------DD-EN
A
---------
K
T
F
-
E
L
C
--
R
EE---------GH
S
F
A
H
F
L
F
I
-EQGMRY----TK-------P-------G
G
Y
L
F
F
L-V
P
D
A-MF-G-T
S
-
D
F
A
K
V
D
K
F
I
K
-KNGH
I
E
G
I
I
KL
P
E
T
-
L
F
K
S
-
E
Q
AR
K
S
I
L
I
L
R
KADVNVK
P
P
K
-----
E
V
L
L
A
N
L
S
SL-----T-------DPSV
T
A
P
I
L
A
E
I
E
N
W
FKSKQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
100.00
97%
-127
- C4 -
2F8L
8
?
A:
[14-341]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
E
A
T
-------
Q
E
L
F
Q
V
L
D
N
-
T
A
I
I
L
Q
N
E
L
E
I
S
Y
L
E
A
V
Y
E
-
T
G
------
E
N
L
F
Q
K
E
V
L
Q
K
----
E
----
E
K
Q
L
K
L
Q
A
S
Y
E
S
-
I
E
L
E
N
F
-
S
N
-
E
E
I
R
K
G
L
----------
Q
L
A
L
L
K
G
M
K
H
-
G
I
Q
V
N
H
Q
M
T
P
D
S
I
G
F
I
V
A
Y
L
L
E
K
V
I
Q
K
K
--
K
N
V
S
I
L
D
P
A
C
G
T
A
N
L
L
T
T
V
I
N
Q
L
--------
E
L
K
G
--------
D
V
-
D
V
H
A
S
G
V
D
V
D
D
L
L
I
S
L
A
L
V
G
----
A
------
D
L
Q
R
------
Q
K
-
M
T
L
--
L
H
-
Q
D
G
L
A
N
-
L
---------------------
L
-----
V
-----
D
P
----------------
V
D
V
V
I
S
-
D
L
P
---------
V
G
Y
------
Y
P
-------
D
D
-
E
N
A
---------
K
T
F
-
E
L
C
--
R
E
E
---------
G
H
S
F
A
H
F
L
F
I
-
E
Q
G
M
R
Y
----
T
K
-------
P
-------
G
G
Y
L
F
F
L
-
V
P
D
A
-
M
F
-
G
-
T
S
-
D
F
A
K
V
D
K
F
I
K
-
K
N
G
H
I
E
G
I
I
K
L
P
E
T
-
L
F
K
S
--
Q
A
R
K
S
I
L
I
L
E
K
A
D
V
D
V
K
P
P
K
-----
E
V
L
L
A
N
L
S
S
L
-----
T
-------
D
P
S
V
T
A
P
I
L
A
E
I
E
N
W
F
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
96.84
94%
-122
- C4 -
2F8L
8
?
A:
[14-341]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
E
A
T
-------
Q
E
L
F
Q
V
L
D
N
-
T
A
I
I
L
Q
N
E
L
E
I
S
Y
L
E
A
V
Y
E
-
T
G
------
E
N
L
F
Q
K
E
V
L
Q
K
----
E
----
E
K
Q
L
K
L
Q
A
S
Y
E
S
-
I
E
L
E
N
F
-
S
N
E
E
I
R
K
G
L
Q
----------
L
A
L
L
K
G
M
K
H
G
--
I
Q
V
N
H
Q
M
T
P
D
S
I
G
F
I
V
A
Y
L
L
E
K
V
I
Q
K
K
--
K
N
V
S
I
L
D
P
A
C
G
T
A
N
L
L
T
T
V
I
N
Q
L
--------
E
L
K
G
--------
D
V
-
D
V
H
A
S
G
V
D
V
D
D
L
L
I
S
L
A
L
V
G
----
A
------
D
L
Q
R
------
Q
K
-
M
T
L
--
L
H
-
Q
D
G
L
A
N
-
L
---------------------
L
-----
V
-----
D
P
----------------
V
D
V
V
I
S
-
D
L
P
---------
V
G
Y
------
Y
P
-------
D
D
-
E
N
A
---------
K
T
F
-
E
L
C
--
R
E
E
---------
G
H
S
F
A
H
F
L
F
I
-
E
Q
G
M
R
Y
----
T
K
-------
P
-------
G
G
Y
L
F
F
L
-
V
P
D
A
-
M
F
-
G
-
T
S
-
D
F
A
K
V
D
K
F
I
K
-
K
N
G
H
I
E
G
I
I
K
L
P
E
T
-
L
F
K
S
--
Q
A
R
K
S
I
L
I
L
E
K
A
D
V
D
V
K
P
P
K
-----
E
V
L
L
A
N
L
S
S
L
-----
T
-------
D
P
S
V
T
A
P
I
L
A
E
I
E
N
W
F
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
56.12
17%
-85
- C4 -
3UFB
-
?
A:
[12-495]
-----------------------------------------------------------------------------------------------------------------------------ADQPMTT
A
Q
Q
L
G
A
I
V
K
S
S
R
Q
I
M
R
K
DKGLNGDL
D
R
L
P
M
L
T
W
I
M
F
L
K
F
L
D
D
L
E
Q
M
R
E
T
E
A
V
L
E
G
K
S
F
Q
P
AIEAPYR
W
R
D
W
A
A
IEGGITG
D
E
L
I
A
F
I
N
N
D
E
A
M
R
P
D
G
T
R
G
I
G
L
F
A
Y
L
R
S
-
L
Q
GDNGGD
R
R
D
V
I
A
T
V
F
K
G
----
M
Q
N
R
M
I
N
G
Y
L
L
R
D
V
V
D
K
-
I
N
G
I
H
F
-
N
S
-
S
E
E
M
H
T
L
----------
S
R
L
Y
E
T
M
L
R
E
-
M
R
D
A
A
G
D
S
G
E
F
Y
T
P
R
P
V
V
R
F
M
V
E
V
M
D
P
Q
--
L
G
E
S
V
L
D
P
A
C
G
T
G
G
F
L
V
E
A
F
E
H
L
E
R
Q
CKT
V
E
D
R
E
V
--------
L
Q
-
E
S
S
I
F
G
G
E
A
K
S
L
P
Y
L
L
V
Q
M
N
----
L
------
L
L
H
G
L-----
E
Y
-
P
R
I
--
D
P
-
E
N
S
L
R
F
-
P
---------------------
L
-----
R
EMGDK
D
R
----------------
V
D
V
I
L
T
-
N
P
P
---------
F
G
G
------
E
E
-------
E
K
-
G
I
L
---------
G
N
F
P
E
D
M
--
Q
T
A
---------
E
T
A
M
L
F
L
Q
L
I
-
M
R
K
L
K
R
PGHG
S
D
-------
N
-------
G
G
R
A
A
V
V
-
V
P
N
G
-
T
L
F
S
-
D
G
-
I
S
A
R
I
K
E
E
L
L
-
K
N
F
N
L
H
T
I
V
R
L
P
E
G
-
V
F
A
P
-
Y
T
D
I
A
G
N
L
L
F
F
D
R
S
---
G
P
T
D
-----
D
I
W
Y
Y
Q
I
T
V
P
-----
E
GRKKYTK
T
K
P
M
E
S
H
E
F
D
E
C
L
N
W
W
S
N
R
I
V
N
QN
A
W
K
E
S
A
S
E
I
I
KYSESGQLIDVNLDRKNPNSLEVLEH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
53.68
24%
-117
- C4 -
3UFB
-
?
A:
[205-397]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
R
F
M
V
E
-
V
M
D
P
Q
--
L
G
E
S
V
L
D
P
A
C
G
T
G
G
F
L
V
E
A
F
E
H
L
--------
E
R
Q
---------------
C
K
T
V
E
D
R
E
V
L
Q
E
S
S
I
F
G
----
G
------
E
A
K
S
L
P
Y
L
L
V
Q
M
-
N
L
L
--
L
H
---
G
L
E
Y
-
P
---------------------
R
-----
I
-----
D
P
ENSLRFPLREMGDKDR
V
D
V
I
L
T
-
N
P
P
F
G
G
E
E
E
K
G
I
L
G
N
------
F
P
-------
E
D
M
Q
T
A
---------
E
T
------------------------
A
M
L
F
L
-
Q
L
I
M
R
K
----
L
K
-------
R
PGHGSDN
G
G
R
A
A
V
V
-
V
P
N
G
T
L
F
-
S
-
D
G
-
I
S
A
R
I
K
E
E
L
L
-
K
N
F
N
L
H
T
I
V
R
L
P
E
G
-
V
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
53.62
24%
-110
- C4 -
2IH4
4
MTTA_THEAQ
A:
[22-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
P
P
E
V
V
D
F
M
V
S
-----
L
A
E
A
P
--
R
G
G
R
V
L
E
P
A
C
A
H
G
P
F
L
R
A
F
---
R
--------
E
A
H
G
--------
T
A
--
Y
R
F
V
G
V
E
I
D
P
K
A
L
D
L
P
P
W
A
E
G
I
L
A
------
D
F
-------------
L
--
L
W
-
E
P
G
E
A
------------------------------------------------------
F
D
L
I
L
G
-
N
P
P
---------
Y
G
I
V
GEASK
Y
P
IHVF
K
A
V
K
D
-
L
Y
K
---------
K
A
F
-
S
T
W
--
K
G
K
---------
Y
N
L
Y
G
A
F
L
---
E
K
A
V
R
L
----
L
K
-------
P
-------
G
G
V
L
V
F
V
-
V
P
A
T
-
W
L
-
V
-
L
E
-
D
F
A
L
L
R
E
F
L
A
-
R
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
53.14
24%
-110
- C4 -
2IH5
4
MTTA_THEAQ
A:
[22-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
P
P
E
V
V
D
F
M
V
S
-----
L
A
E
A
P
--
R
G
G
R
V
L
E
P
A
C
A
H
G
P
F
L
R
A
F
---
R
--------
E
A
H
G
--------
T
A
--
Y
R
F
V
G
V
E
I
D
P
K
A
L
D
L
P
P
W
A
E
G
I
L
A
------
D
F
-------------
L
--
L
W
-
E
P
G
E
A
------------------------------------------------------
F
D
L
I
L
G
-
N
P
P
---------
Y
G
I
V
GEASK
Y
P
I
H
V
F
K
A
V
K
D
-
L
Y
K
---------
K
A
F
-
S
T
W
--
K
G
K
---------
Y
N
L
Y
G
A
F
L
---
E
K
A
V
R
L
----
L
K
-------
P
-------
G
G
V
L
V
F
V
-
V
P
A
T
-
W
L
-
V
-
L
E
-
D
F
A
L
L
R
E
F
L
A
-
R
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
52.72
24%
-112
- C4 -
2JG3
6
MTTA_THEAQ
A:
[23-185]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
P
P
E
V
V
D
F
M
V
S
-----
L
A
E
A
P
--
R
G
G
R
V
L
E
P
A
C
A
H
G
P
F
L
R
A
F
---
R
--------
E
A
H
G
--------
T
A
--
Y
R
F
V
G
V
E
I
D
P
K
A
L
D
L
P
P
W
A
E
G
I
L
A
------
D
F
-------------
L
--
L
W
-
E
P
G
E
A
------------------------------------------------------
F
D
L
I
L
G
-
N
P
P
---------
Y
G
I
V
GEASK
Y
P
I
H
V
F
K
A
V
K
D
-
L
Y
K
---------
K
A
F
-
S
T
W
--
K
G
K
---------
Y
N
L
Y
G
A
F
L
---
E
K
A
V
R
L
----
L
K
-------
P
-------
G
G
V
L
V
F
V
-
V
P
A
T
-
W
L
-
V
-
L
E
-
D
F
A
L
L
R
E
F
L
A
-
R
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
HHSearch
52.64
18%
-80
- C4 -
3UFB
-
?
A:
[153-426]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
G
Y
L
L
R
D
V
V
D
K
I
N
G
-
I
H
F
N
S
S
E
E
M
-
H
T
L
S
R
L
Y
----------
E
T
M
L
R
E
M
R
D
A
-
A
G
D
S
G
E
F
Y
T
P
R
P
V
V
R
F
M
V
E
V
M
D
----
P
Q
--
L
G
E
S
V
L
D
P
A
C
G
T
G
G
F
L
V
E
A
F
E
H
L
--------
E
R
Q
C
KT
V
E
D
R
E
V
L
Q
-
E
S
S
I
F
G
G
E
A
K
S
L
P
Y
L
L
V
Q
M
N
----
L
------
L
L
H
G
------
L
E
Y
P
R
I
--
D
P
-
E
N
S
L
R
F
-
P
---------------------
L
REMGD
K
-----
D
R
----------------
V
D
V
I
L
T
-
N
P
P
---------
F
G
G
------
E
E
-------
E
K
-
G
I
L
---------
G
N
F
-
P
E
----
D
M
---------
Q
T
A
E
T
A
M
L
F
L
-
Q
L
I
M
R
K
----
L
K
RPGHGSD
N
-------
G
G
R
A
A
V
V
-
V
P
N
G
-
T
L
-
F
-
S
D
G
I
S
A
R
I
K
E
E
L
L
-
K
N
F
N
L
H
T
I
V
R
L
P
E
G
-
V
F
A
P
Y
T
D
I
A
G
N
L
L
F
F
D
R
S
G
P
----
T
D
-----
D
I
W
Y
Y
Q
I
T
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
52.49
24%
-110
- C4 -
2IBS
3
MTTA_THEAQ
A:
[22-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
P
P
E
V
V
D
F
M
V
S
-----
L
A
E
A
P
--
R
G
G
R
V
L
E
P
A
C
A
H
G
P
F
L
R
A
F
---
R
--------
E
A
H
G
--------
T
A
--
Y
R
F
V
G
V
E
I
D
P
K
A
L
D
L
P
P
W
A
E
G
I
L
A
------
D
F
-------------
L
--
L
W
-
E
P
G
E
A
------------------------------------------------------
F
D
L
I
L
G
-
N
P
P
---------
Y
G
I
V
GEASK
Y
P
I
H
V
F
K
A
V
K
D
-
L
Y
K
---------
K
A
F
-
S
T
W
--
K
G
K
---------
Y
N
L
Y
G
A
F
L
---
E
K
A
V
R
L
----
L
K
-------
P
-------
G
G
V
L
V
F
V
-
V
P
A
T
-
W
L
-
V
-
L
E
-
D
F
A
L
L
R
E
F
L
A
-
R
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
52.37
20%
-118
- C4 -
2IH2
5
MTTA_THEAQ
A:
[21-213]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
T
P
P
E
V
V
D
F
M
V
S
L
A
E
A
----
P
--
R
G
G
R
V
L
E
P
A
C
A
H
G
P
F
L
R
A
F
R
E
A
H
--------
G
T
-------------
A
Y
R
F
V
G
V
E
I
D
P
K
A
L
D
L
P
P
W
-------------------------
A
E
G
--
I
L
-
A
D
F
L
L
W
-
E
---------------------
P
-----
G
-----
E
A
----------------
F
D
L
I
L
G
-
N
P
P
---------
Y
G
I
------
V
G
-------
E
A
-
S
K
Y
P
I
H
V
F
K
A
V
K
D
L
Y
-
K
K
A
F
S
T
W
K
---------
G
K
Y
N
L
Y
G
A
F
L
-
E
K
A
V
R
L
----
L
K
-------
P
-------
G
G
V
L
V
F
V
-
V
P
A
T
-
W
L
-
V
-
L
E
-
D
F
A
L
L
R
E
F
L
A
-
R
E
G
K
T
S
-
V
Y
Y
L
G
-
E
-
V
F
P
Q
-
K
K
V
S
A
V
V
I
R
F
Q
K
S
G
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
52.35
24%
-109
- C4 -
2NP7
5
MTTA_THEAQ
A:
[22-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
P
P
E
V
V
D
F
M
V
S
-----
L
A
E
A
P
--
R
G
G
R
V
L
E
P
A
C
A
H
G
P
F
L
R
A
F
---
R
--------
E
A
H
G
--------
T
A
--
Y
R
F
V
G
V
E
I
D
P
K
A
L
D
L
P
P
W
A
E
G
I
L
A
------
D
F
-------------
L
--
L
W
-
E
P
G
E
A
------------------------------------------------------
F
D
L
I
L
G
-
N
P
P
---------
Y
G
I
V
GEASK
Y
P
I
H
V
F
K
A
V
K
D
-
L
Y
K
---------
K
A
F
-
S
T
W
--
K
G
K
---------
Y
N
L
Y
G
A
F
L
---
E
K
A
V
R
L
----
L
K
-------
P
-------
G
G
V
L
V
F
V
-
V
P
A
T
-
W
L
-
V
-
L
E
-
D
F
A
L
L
R
E
F
L
A
-
R
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
52.31
22%
-96
- C4 -
1AQJ
1
MTTA_THEAQ
A:
[22-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
P
P
E
V
V
D
F
M
V
S
-----
L
A
E
A
P
--
R
G
G
R
V
L
E
P
A
C
A
H
G
P
F
L
-----------------
R
A
--------
F
R
-
E
A
H
G
T
G
Y
R
---------
F
V
G
----
V
------
E
I
D
P
------
K
A
-
L
D
L
P
P
W
A
-
E
G
I
L
A
D
F
L
---------------------
L
-----
W
-----
E
P
GEA-------------
F
D
L
I
L
G
-
N
P
P
---------
Y
G
I
V-------A
V
-----
K
D
-
L
Y
K
---------
K
A
F
-
S
T
W
--
K
G
K
---------
Y
N
L
Y
G
A
F
L
---
E
K
A
V
R
L
----
L
K
-------
P
-------
G
G
V
L
V
F
V
-
V
P
A
T
-
W
L
-
V
-
L
E
-
D
F
A
L
L
R
E
F
L
A
-
R
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
51.57
24%
-106
- C4 -
2IBT
4
MTTA_THEAQ
A:
[22-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
P
P
E
V
V
D
F
M
V
S
-----
L
A
E
A
P
--
R
G
G
R
V
L
E
P
A
C
A
H
G
P
F
L
R
A
F
---
R
--------
E
A
H
G
--------
T
A
--
Y
R
F
V
G
V
E
I
D
P
K
A
L
D
L
P
P
W
A
E
G
I
L
A
------
D
F
-------------
L
--
L
W
-
E
P
G
E
A
------------------------------------------------------
F
D
L
I
L
G
-
N
P
P
---------
Y
G
I
V
GEASK
Y
P
I
H
V
F
K
A
V
K
D
-
L
Y
K
---------
K
A
F
-
S
T
W
--
K
G
K
---------
Y
N
L
Y
G
A
F
L
---
E
K
A
V
R
L
----
L
K
-------
P
-------
G
G
V
L
V
F
V
-
V
P
A
T
-
W
L
-
V
-
L
E
-
D
F
A
L
L
R
E
F
L
A
-
R
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
51.37
24%
-108
- C4 -
2IH2
5
MTTA_THEAQ
A:
[22-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
P
P
E
V
V
D
F
M
V
S
-----
L
A
E
A
P
--
R
G
G
R
V
L
E
P
A
C
A
H
G
P
F
L
R
A
F
---
R
--------
E
A
H
G
--------
T
A
--
Y
R
F
V
G
V
E
I
D
P
K
A
L
D
L
P
P
W
A
E
G
I
L
A
------
D
F
-------------
L
--
L
W
-
E
P
G
E
A
------------------------------------------------------
F
D
L
I
L
G
-
N
P
P
---------
Y
G
I
V
GEASK
Y
P
I
H
V
F
K
A
V
K
D
-
L
Y
K
---------
K
A
F
-
S
T
W
--
K
G
K
---------
Y
N
L
Y
G
A
F
L
---
E
K
A
V
R
L
----
L
K
-------
P
-------
G
G
V
L
V
F
V
-
V
P
A
T
-
W
L
-
V
-
L
E
-
D
F
A
L
L
R
E
F
L
A
-
R
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
51.35
22%
-95
- C4 -
1AQI
1
MTTA_THEAQ
A:
[22-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
P
P
E
V
V
D
F
M
V
S
-----
L
A
E
A
P
--
R
G
G
R
V
L
E
P
A
C
A
H
G
P
F
L
-----------------
R
A
--------
F
R
-
E
A
H
G
T
G
Y
R
---------
F
V
G
----
V
------
E
I
D
P
------
K
A
-
L
D
L
P
P
W
A
-
E
G
I
L
A
D
F
L
---------------------
L
-----
W
-----
E
P
GEA-------------
F
D
L
I
L
G
-
N
P
P
---------
Y
G
I
V-------KAV----
K
D
-
L
Y
K
---------
K
A
F
-
S
T
W
--
K
G
K
---------
Y
N
L
Y
G
A
F
L
---
E
K
A
V
R
L
----
L
K
-------
P
-------
G
G
V
L
V
F
V
-
V
P
A
T
-
W
L
-
V
-
L
E
-
D
F
A
L
L
R
E
F
L
A
-
R
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
50.93
17%
-57
- C4 -
2AR0
7
T1MK_ECOLI
A:
[6-529]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N
D
L
V
A
K
L
-------
W
K
L
C
D
N
L
R
D
-
G
G
V
S
Y
Q
N
Y
V
N
E
L
A
S
L
L
F
L
K
M
C
K
------
E
T
G
Q
E
A
E
Y
L
P
E
GYR
W
D
D
L
K
S
R
I
G
Q
E
Q
L
Q
F
Y
R
K
M
L
V
H
L
G
E
-
D
D
-
K
K
L
V
Q
A
V
F
HNVSTTITE
P
K
Q
I
T
A
L
V
S
N
M
D
S
L
D
W
Q
Y
F
T
P
R
P
L
I
K
T
I
I
H
L
L
K
P
----
Q
--
P
R
E
V
V
Q
D
P
A
A
G
T
A
G
F
L
I
E
A
D
R
Y
V
--------
K
S
Q
T
--------
N
--
D
L
D
D
L
D
G
D
T
Q
D
F
Q
I
H
R
A
F
I
G
----
L
------
E
L
V
P
------
G
T
-
R
R
L
--
A
L
M
N
C
L
L
H
D
-
I
EGNLDHGGA
I
R
L
G
N
TLG
S
D
G
E
N
-----
L
-----
P
K
----------------
A
H
I
V
A
T
-
N
P
P
---------
F
G
S
------
A
A
-------
G
T
-
N
I
T
---------
R
T
F
-
V
----------------
H
P
T
S
N
K
Q
L
C
F
M
Q
H
I
I
E
T
----
L
H
-------
P
-------
G
G
R
A
A
V
V
-
V
P
D
N
-
V
L
-
F
-
E
G
-
G
K
G
T
D
I
R
R
D
L
M
D
K
C
H
L
H
T
I
L
R
L
P
T
G
-
I
F
Y
A
-
Q
G
V
K
T
N
V
L
F
F
T
K
G
T
V
A
N
P
N
Q
D
KNCTD
D
V
W
V
Y
D
L
R
T
N
MPSFG
K
-------
R
T
P
F
T
D
E
H
L
Q
P
F
E
R
V
Y
G
E
D
P
HGLS
P
R
T
E
G
EWSFNAEE
T
E
V
A
DSEENKNTD
Q
H
L
A
T
SR
W
R
K
F
S
R
E
W
I
R
T
A
KSDSLDISWLKDKDPE
P
D
V
L
A
A
E
A
M
G
E
L
V
Q
A
L
S
E
L
D
A
L
M
R
E
LGASDEA
D
L
Q
R
Q
L
L
E
E
A
FGGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
50.81
24%
-105
- C4 -
2NP6
3
MTTA_THEAQ
A:
[22-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
P
P
E
V
V
D
F
M
V
S
-----
L
A
E
A
P
--
R
G
G
R
V
L
E
P
A
C
A
H
G
P
F
L
R
A
F
---
R
--------
E
A
H
G
--------
T
A
--
Y
R
F
V
G
V
E
I
D
P
K
A
L
D
L
P
P
W
A
E
G
I
L
A
------
D
F
-------------
L
--
L
W
-
E
P
G
E
A
------------------------------------------------------
F
D
L
I
L
G
-
N
P
P
---------
Y
G
I
V
GEASK
Y
P
IHVF
K
A
V
K
D
-
L
Y
K
---------
K
A
F
-
S
T
W
--
K
G
K
---------
Y
N
L
Y
G
A
F
L
---
E
K
A
V
R
L
----
L
K
-------
P
-------
G
G
V
L
V
F
V
-
V
P
A
T
-
W
L
-
V
-
L
E
-
D
F
A
L
L
R
E
F
L
A
-
R
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
50.60
22%
-98
- C4 -
2ADM
1
MTTA_THEAQ
A:
[22-185]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
P
P
E
V
V
D
F
M
V
S
-----
L
A
E
A
P
--
R
G
G
R
V
L
E
P
A
C
A
H
G
P
F
L
-----------------
R
A
--------
F
R
-
E
A
H
G
T
G
Y
R
---------
F
V
G
----
V
------
E
I
D
P
------
K
A
-
L
D
L
PP
W
A
-
E
G
I
L
A
D
F
L
---------------------
L
-----
W
-----
E
P
GEA-------------
F
D
L
I
L
G
-
N
P
P
---------
Y
G
I
VG------V
F
K
A
V
--
K
D
-
L
Y
K
---------
K
A
F
-
S
T
W
--
K
G
K
---------
Y
N
L
Y
G
A
F
L
---
E
K
A
V
R
L
----
L
K
-------
P
-------
G
G
V
L
V
F
V
-
V
P
A
T
-
W
L
-
V
-
L
E
-
D
F
A
L
L
R
E
F
L
A
-
R
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
50.19
14%
-64
- C4 -
3S1S
26
?
A:
[6-875]
LNNCVFS
Y
L
P
S
YGDDEVSV
Y
H
P
I
C
E
A
A
L
N
Q
A
L
V
N
T
GLDST
Y
E
V
V
H
HELVGSIEADFVIKNKQTKKYL
L
I
V
E
V
K
RT
K
S
Q
V
S
S
T
R
Y
R
L
Q
A
Q
S
Y
V
R
E
A
NIKVEQH
Y
Y
C
L
T
NLE
I
I
D
F
F
K
H
D
PNKPVVSQQIIEPSPIVVGNFSDT
V
S
E
F
Y
N
R
L
V
E
A
F
Q
N
I
I
D
I
S
V
N
DAGTYK
S
S
T
A
N
L
V
D
I
L
E
N
R
K
DN
S
T
S
W
H
Q
A
L
V
V
A
G
Y
E
Y
I
R
G
V
L
-------
R
G
Q
N
V
E
V
P
T
-
R
D
A
I
Y
F
K
S
R
P
G
R
L
L
E
E
G
R
K
-
I
D
------
F
N
V
L
F
S
E
P
E
P
N
----
T
N
D
N
D
I
W
N
V
N
L
L
S
S
L
N
D
-
L
G
R
R
I
L
-
T
G
-
D
E
L
A
E
L
I
----------
H
D
I
A
T
R
G
R
G
H
-
E
G
V
V
P
---
T
D
I
E
L
G
K
V
L
S
I
I
S
Q
H
I
L
G
R
P
L
T
E
D
E
V
I
S
D
P
A
A
G
S
G
N
L
L
A
T
V
S
A
G
F
-----------
N
--------
N
V
M
P
R
Q
I
W
A
N
D
I
E
T
L
F
L
E
L
L
S
I
R
----
L
G
L
L
FPQ
L
V
S
S
------
N
N
-
A
P
T
--
I
T
-
G
E
D
V
C
S
-
L
---------------------
N
-----
P
-----
E
D
FA--------------
N
V
S
V
V
V
M
N
P
P
YV-------
S
G
V
------
T
D
-------
P
A
-
I
K
R
---------
K
F
A
-
H
K
I
--
I
Q
L
TGNRPQTLF
G
Q
I
G
V
E
A
L
F
L
-
E
L
V
T
E
L
----
V
Q
-------
D
-------
G
T
V
I
S
A
I
M
P
K
Q
Y
-
L
T
-
A
Q
G
N
-
E
S
K
A
F
R
E
F
L
V
-
G
N
F
G
L
E
H
I
F
L
Y
P
R
E
G
L
F
E
E
-
V
I
K
D
T
V
V
F
V
G
R
K
G
----
S
S
V
E
-----
E
I
E
V
L
D
S
F
T
P
-----
L
-------
E
Q
V
D
L
H
N
L
K
R
A
L
S
N
S
S
N
E
Q
I
I
Q
P
M
G
M
E
L
R
K
E
K
R
E
E
L
E
N
R
VTVGWRHITS
N
G
R
V
A
E
E
W
I
T
N
NLESHCIRLVASD
Y
D
L
R
R
GRVGNKGA
S
D
L
L
F
INSK
K
K
L
W
D
L
LDESVPRDWL
Y
P
A
L
RKVNEINTPIFNEDATP
V
R
F
L
C
P
P
NSAYQDGT
G
E
S
I
I
L
D
K
I
L
D
V
Y
V
D
F
Q
V
Y
K
SKQKKFEKS
K
E
E
L
K
E
I
L
Y
K
E
S
D
F
YSSEH
T
V
F
I
P
RALRRSA
R
A
F
I
N
E
Q
K
V
F
C
S
TN
A
L
E
V
F
GGN
S
E
E
M
W
L
L
L
S
W
L
S
S
V
F
A
Q
L
Q
F
E
A
M
A
K
DQE
G
E
R
K
L
E
K
K
S
I
Q
N
L
Y
I
P
NLGDID
D
V
L
K
Q
D
L
I
E
E
V
R
E
IHFFDLC
R
P
R
V
R
K
L
D
L
L
W
A
K
V
F
WSGN
E
M
S
K
T
K
E
A
A
E
L
L
E
D
L
V
F
E
R
YPEGSQ