@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1808: (2016-03-29 )
MTKIAFVFPGQGAQKVGMGQDVAAEYPEAKKIYDDADERLGFSITEIITEGPIELLTKSENAQPALVSTSVAILRALETYGVKADYVAGHSLGEYSALVAGGFLEASDAIYLVRKRGELMEAAVPNGAGAMAAVLGVDRETLKTITEEVTKEGDAVQLANLNCPGQIVISGTTAGVEKAGEKAKESGAKRVLPLAVSGPFHSSLMEPAALAFRDVLAEVKISDGQIPVVNNVDAKETTDKSEISDKLIKQIYSPVLWEDIVEELIKNGVDTFVEIGSGKVLAGLIKKINRDVTVLSAGDAESVKSVAATLKGE
Atome Classification :
(27 SA)
.........10........20........30.--.......40.......-.50........60........70.----....-.--..-80.-.----..----.-.------.-..90........100.......110.......120...-....130.......140.......150......---.160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
T
K
I
A
F
V
FPGQGAQKVGMG
Q
D
V
A
A
EYP
E
A
K
K
I
--YDD
A
D
E
RLG
F
S
I
T
E
I
I
-TEG
P
I
E
L
L
TKSENAQP
A
L
V
S
T
S
V
A
----
I
L
R
A
-
L
--
E
T
-Y-G-V----KA----D-Y------V-AGHSLG
E
Y
S
A
L
V
AGGFLEAS
D
A
I
Y
L
V
RKRG
E
L
M
E
AAVP-NGA
G
A
M
A
A
V
LGV
D
R
E
T
L
K
T
I
T
E
E
V
TKEGD
A
V
Q
L
---ANLNCP
G
Q
I
V
I
SGTTA
G
V
E
K
A
G
E
K
A
K
ESGA
K
R
V
L
P
L
A
VSGP
F
H
S
S
L
M
E
P
A
A
L
A
F
R
D
V
L
A
E
V
KISDGQ
I
P
V
V
NNVDAKETT
D
K
S
E
I
S
D
K
L
I
K
Q
I
Y
S
P
V
L
W
E
D
I
V
E
E
L
I
KN
G
V
D
T
F
V
EIGS
G
K
V
L
A
G
L
I
K
K
INR
D
V
T
V
L
SAG
D
A
E
S
V
K
S
V
A
A
T
LKGE
25
HHSearch
94.45
48%
-90
- C1 -
3IM9
3
FABD_STAAM
A:
[10-313]
-
S
H
M
A
I
I
F
P
G
Q
G
A
Q
K
V
G
M
A
Q
D
L
F
N
N
N
D
Q
A
T
E
I
--
L
T
S
A
A
K
T
L
D
F
D
I
L
E
T
M
-
F
T
D
E
E
G
K
L
G
E
T
E
N
T
Q
P
A
L
L
T
H
S
S
A
----
L
L
A
A
-
L
--
K
N
-----
L
----
N
P
----
D
-
F
------
T
-
M
G
H
S
L
G
E
Y
S
S
L
V
A
A
D
V
L
S
F
E
D
A
V
K
I
V
R
K
R
G
Q
L
M
A
Q
A
F
P
-
T
G
V
G
S
M
A
A
V
L
G
L
D
F
D
K
V
D
E
I
C
K
S
L
S
S
D
D
K
I
I
E
P
---
A
N
I
N
C
P
G
Q
I
V
V
S
G
H
K
A
L
I
D
E
L
V
E
K
G
K
S
L
G
A
K
R
V
M
P
L
A
V
S
G
P
F
H
S
S
L
M
K
V
I
E
E
D
F
S
S
Y
I
N
Q
F
E
W
R
D
A
K
F
P
V
V
Q
N
V
N
A
Q
G
E
T
D
K
E
V
I
K
S
N
M
V
K
Q
L
Y
S
P
V
Q
F
I
N
S
T
E
W
L
I
D
Q
G
V
D
H
F
I
E
I
G
P
G
K
V
L
S
G
L
I
K
K
I
N
R
D
V
K
L
T
S
I
Q
T
L
E
D
V
K
G
W
N
------
10
PsiBlast_PDB
93.90
42%
-97
- C1 -
3PTW
-
?
A:
[3-309]
--
K
L
G
F
L
F
A
G
Q
G
A
Q
Y
V
G
M
G
K
E
F
F
D
N
F
E
E
S
K
E
V
--
F
K
R
S
S
E
A
L
G
I
D
M
E
E
L
C
-
F
N
D
P
E
G
L
L
N
K
T
E
F
T
Q
P
A
I
I
T
T
N
M
A
----
I
L
T
A
-
L
--
D
K
-
L
-
G
-
V
----
K
S
----
H
-
I
------
S
-
C
G
L
S
L
G
E
Y
S
A
L
I
H
S
G
A
I
N
F
E
D
G
V
K
L
V
K
K
R
G
K
F
M
Q
E
A
V
A
-
E
G
I
G
G
M
V
A
V
L
R
M
T
P
E
Q
V
D
E
I
I
E
K
S
S
P
Y
G
-
I
V
E
G
---
A
N
Y
N
S
P
G
Q
I
V
I
S
G
E
L
V
A
L
E
K
A
M
E
F
I
K
E
V
G
G
-
R
A
I
K
L
P
V
S
A
P
F
H
C
S
M
L
Q
P
A
A
E
K
L
E
D
E
L
N
K
I
S
I
N
K
L
N
G
I
V
M
S
N
V
K
G
E
A
Y
L
E
D
D
N
I
I
E
L
L
T
S
Q
V
K
K
P
V
L
F
I
N
D
I
E
K
M
I
E
S
G
V
D
T
F
I
E
I
G
P
G
K
A
L
S
G
F
V
K
K
I
N
K
N
V
T
V
L
N
V
E
D
L
K
S
L
E
K
T
L
S
K
L
R
--
1
PsiBlast_PDB
93.76
48%
-90
- C1 -
3IM9
3
FABD_STAAM
A:
[10-310]
-
S
H
M
A
I
I
F
P
G
Q
G
A
Q
K
V
G
M
A
Q
D
L
F
N
N
N
D
Q
A
T
E
I
--
L
T
S
A
A
K
T
L
D
F
D
I
L
E
T
M
-
F
T
D
E
E
G
K
L
G
E
T
E
N
T
Q
P
A
L
L
T
H
S
S
A
----
L
L
A
A
-
L
--
K
N
-----
L
----
N
P
----
D
-
F
------
T
-
M
G
H
S
L
G
E
Y
S
S
L
V
A
A
D
V
L
S
F
E
D
A
V
K
I
V
R
K
R
G
Q
L
M
A
Q
A
F
P
-
T
G
V
G
S
M
A
A
V
L
G
L
D
F
D
K
V
D
E
I
C
K
S
L
S
S
D
D
K
I
I
E
P
---
A
N
I
N
C
P
G
Q
I
V
V
S
G
H
K
A
L
I
D
E
L
V
E
K
G
K
S
L
G
A
K
R
V
M
P
L
A
V
S
G
P
F
H
S
S
L
M
K
V
I
E
E
D
F
S
S
Y
I
N
Q
F
E
W
R
D
A
K
F
P
V
V
Q
N
V
N
A
Q
G
E
T
D
K
E
V
I
K
S
N
M
V
K
Q
L
Y
S
P
V
Q
F
I
N
S
T
E
W
L
I
D
Q
G
V
D
H
F
I
E
I
G
P
G
K
V
L
S
G
L
I
K
K
I
N
R
D
V
K
L
T
S
I
Q
T
L
E
D
V
K
---------
24
HHSearch
93.21
42%
-98
- C1 -
3PTW
-
?
A:
[2-308]
-
A
K
L
G
F
L
F
A
G
Q
G
A
Q
Y
V
G
M
G
K
E
F
F
D
N
F
E
E
S
K
E
V
--
F
K
R
S
S
E
A
L
G
I
D
M
E
E
L
C
-
F
N
D
P
E
G
L
L
N
K
T
E
F
T
Q
P
A
I
I
T
T
N
M
A
----
I
L
T
A
-
L
--
D
K
-
L
-
G
-
V
----
K
S
----
H
-
I
------
S
-
C
G
L
S
L
G
E
Y
S
A
L
I
H
S
G
A
I
N
F
E
D
G
V
K
L
V
K
K
R
G
K
F
M
Q
E
A
V
A
-
E
G
I
G
G
M
V
A
V
L
R
M
T
P
E
Q
V
D
E
I
I
E
K
S
S
-
P
Y
G
I
V
E
G
---
A
N
Y
N
S
P
G
Q
I
V
I
S
G
E
L
V
A
L
E
K
A
M
E
F
I
K
E
V
G
G
-
R
A
I
K
L
P
V
S
A
P
F
H
C
S
M
L
Q
P
A
A
E
K
L
E
D
E
L
N
K
I
S
I
N
K
L
N
G
I
V
M
S
N
V
K
G
E
A
Y
L
E
D
D
N
I
I
E
L
L
T
S
Q
V
K
K
P
V
L
F
I
N
D
I
E
K
M
I
E
S
G
V
D
T
F
I
E
I
G
P
G
K
A
L
S
G
F
V
K
K
I
N
K
N
V
T
V
L
N
V
E
D
L
K
S
L
E
K
T
L
S
K
L
---
31
HHSearch
91.15
44%
-93
- C1 -
2CUY
-
?
A:
[2-300]
---
Y
A
A
L
F
P
G
Q
G
S
H
R
V
G
M
G
R
A
L
Y
E
A
S
P
A
A
K
E
V
--
L
D
R
A
E
A
A
L
P
G
L
L
-
K
L
M
-
W
E
G
P
E
E
A
L
T
L
T
E
N
Q
Q
P
A
L
L
A
A
G
Y
A
----
A
Y
R
A
-
F
--
L
E
A
G
-
G
-
K
----
P
P
----
A
-
L
------
A
-
A
G
H
S
L
G
E
W
T
A
H
V
A
A
G
T
L
E
L
E
D
A
L
R
L
V
R
L
R
G
R
Y
M
Q
E
A
V
P
-
V
G
E
G
A
M
A
A
V
L
K
L
P
L
E
E
I
Q
K
A
L
E
G
L
----
E
G
V
E
I
---
A
N
L
N
A
P
E
Q
T
V
I
S
G
R
R
Q
A
V
E
E
A
A
E
R
L
K
E
R
R
A
-
R
V
V
F
L
P
V
S
A
P
F
H
S
S
L
M
A
P
A
R
K
R
L
A
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D
L
A
Q
V
P
L
R
R
P
R
F
P
V
Y
S
N
V
T
A
R
P
E
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D
P
E
R
I
R
A
L
L
L
E
Q
I
T
A
P
V
R
W
V
E
I
L
R
D
M
E
A
R
G
V
K
R
F
L
E
F
G
S
G
E
V
L
K
G
L
V
L
R
T
L
K
E
A
E
A
L
S
V
Q
D
P
D
S
L
R
K
A
L
------
23
HHSearch
89.47
43%
-96
- C1 -
3QAT
2
?
A:
[5-317]
-
M
G
A
A
F
T
F
P
G
Q
G
S
Q
L
I
G
M
G
K
V
L
T
E
Q
F
V
A
A
R
M
V
--
F
E
E
V
D
D
A
L
S
E
K
L
S
D
I
I
-
F
E
G
P
A
D
V
L
T
L
T
A
N
A
Q
P
A
L
M
A
V
S
M
A
----
V
I
R
V
-
M
--
E
Q
-
L
-
G
-
L
----
N
V
EKKV
K
-
F
------
V
-
A
G
H
S
L
G
E
Y
S
A
L
C
A
A
G
T
F
S
L
T
D
T
A
R
L
L
R
I
R
G
N
A
M
Q
A
A
V
A
-
V
G
E
G
S
M
A
A
L
I
G
L
D
E
K
D
V
E
E
I
C
E
I
V
A
E
-
E
G
L
C
Q
I
---
A
N
D
N
G
G
G
Q
I
V
I
S
G
E
A
K
A
V
E
T
A
V
E
V
A
S
Q
K
G
A
K
R
A
V
L
L
P
V
S
A
P
F
H
S
A
L
M
Q
P
A
A
N
A
M
K
N
A
L
L
T
V
N
K
T
A
P
I
V
P
L
I
A
N
V
S
V
I
P
E
S
D
P
E
R
I
V
S
L
L
V
Q
Q
V
T
G
R
V
R
W
R
E
T
I
E
W
I
S
A
N
G
V
N
T
L
F
E
I
G
S
G
K
V
L
T
G
L
A
R
R
I
N
K
D
I
K
A
L
T
V
G
T
A
E
E
I
E
A
A
L
R
V
L
G
--
15
PsiBlast_PDB
88.96
43%
-89
- C1 -
2CUY
-
?
A:
[3-297]
----
A
A
L
F
P
G
Q
G
S
H
R
V
G
M
G
R
A
L
Y
E
A
S
P
A
A
K
E
V
--
L
D
R
A
E
A
A
L
P
-
G
L
L
K
L
M
-
W
E
G
P
E
E
A
L
T
L
T
E
N
Q
Q
P
A
L
L
A
A
G
Y
A
----
A
Y
R
A
F
L
--
E
A
-
G
-
G
-
K
----
P
P
----
A
-
L
------
A
-
A
G
H
S
L
G
E
W
T
A
H
V
A
A
G
T
L
E
L
E
D
A
L
R
L
V
R
L
R
G
R
Y
M
Q
E
A
V
P
-
V
G
E
G
A
M
A
A
V
L
K
L
P
L
E
E
I
Q
K
A
L
E
G
L
----
E
G
V
E
I
---
A
N
L
N
A
P
E
Q
T
V
I
S
G
R
R
Q
A
V
E
E
A
A
E
R
L
K
E
R
R
A
-
R
V
V
F
L
P
V
S
A
P
F
H
S
S
L
M
A
P
A
R
K
R
L
A
E
D
L
A
Q
V
P
L
R
R
P
R
F
P
V
Y
S
N
V
T
A
R
P
E
E
D
P
E
R
I
R
A
L
L
L
E
Q
I
T
A
P
V
R
W
V
E
I
L
R
D
M
E
A
R
G
V
K
R
F
L
E
F
G
S
G
E
V
L
K
G
L
V
L
R
T
L
K
E
A
E
A
L
S
V
Q
D
P
D
S
L
R
---------
7
PsiBlast_PDB
88.81
45%
-91
- C1 -
2G2O
1
FABD_ECOLI
A:
[2-307]
--
Q
F
A
F
V
F
P
G
Q
G
S
Q
T
V
G
M
L
A
D
M
A
A
S
Y
P
I
V
E
E
T
--
F
A
E
A
S
A
A
L
G
Y
D
L
W
A
L
T
-
Q
Q
G
P
A
E
E
L
N
K
T
W
Q
T
Q
P
A
L
L
T
A
S
V
A
----
L
Y
R
V
-
W
--
Q
Q
-
Q
-
G
-
G
----
K
A
----
P
A
M
------
M
-
A
G
H
S
L
G
E
Y
S
A
L
V
C
A
G
V
I
D
F
A
D
A
V
R
L
V
E
M
R
G
K
F
M
Q
E
A
V
P
-
E
G
T
G
A
M
A
A
I
I
G
L
D
D
A
S
I
A
K
A
C
E
E
A
A
-
E
G
Q
V
V
S
P
---
V
N
F
N
S
P
G
Q
V
V
I
A
G
H
K
E
A
V
E
R
A
G
A
A
C
K
A
A
G
A
K
R
A
L
P
L
P
V
S
V
P
S
H
C
A
L
M
K
P
A
A
D
K
L
A
V
E
L
A
K
I
T
F
N
A
P
T
V
P
V
V
N
N
V
D
V
K
C
E
T
N
G
D
A
I
R
D
A
L
V
R
Q
L
Y
N
P
V
Q
W
T
K
S
V
E
Y
M
A
A
Q
G
V
E
H
L
Y
E
V
G
P
G
K
V
L
T
G
L
T
K
R
I
---
V
D
T
L
T
A
S
A
L
N
E
P
S
A
M
A
A
A
L
E
--
29
HHSearch
88.67
38%
-93
* C1 *
3TQE
3
?
A:
[6-312]
-
Q
S
F
A
F
V
F
P
G
Q
G
S
Q
H
L
G
M
L
A
E
L
G
L
Q
Q
P
I
V
L
E
T
--
F
Q
Q
A
S
S
A
L
A
Y
D
L
W
A
L
V
-
Q
H
G
P
Q
E
R
L
D
Q
T
Q
F
T
Q
P
A
L
L
T
A
D
V
A
----
I
F
R
C
-
W
--
E
A
-
L
-
G
G
P
----
K
P
----
Q
-
V
------
M
-
A
G
H
S
L
G
E
Y
A
A
L
V
C
A
G
A
L
K
F
E
E
A
V
K
L
V
E
K
R
G
Q
Y
M
Q
E
A
V
P
-
V
G
E
G
A
M
G
A
I
I
G
L
N
E
A
E
I
E
S
I
C
E
N
A
A
-
L
G
Q
V
V
Q
P
---
A
N
L
N
S
T
D
Q
T
V
I
S
G
H
S
E
A
V
D
R
A
L
N
M
A
K
T
E
G
A
K
I
A
K
R
I
P
V
S
V
P
S
H
C
P
L
M
Q
P
A
A
D
R
L
A
Q
D
I
A
K
I
S
I
D
S
P
K
V
P
V
I
H
N
V
D
V
V
D
H
N
E
A
N
I
I
R
G
A
L
I
K
Q
L
V
R
P
V
R
W
V
E
T
I
K
Y
I
E
E
Q
G
I
K
V
F
M
E
C
G
P
D
N
K
L
A
G
L
I
K
R
I
D
R
Q
S
E
I
L
P
L
T
---
T
T
E
L
I
L
T
A
I
K
--
6
PsiBlast_PDB
88.48
45%
-90
- C1 -
2G1H
1
FABD_ECOLI
A:
[2-307]
--
Q
F
A
F
V
F
P
G
Q
G
S
Q
T
V
G
M
L
A
D
M
A
A
S
Y
P
I
V
E
E
T
--
F
A
E
A
S
A
A
L
G
Y
D
L
W
A
L
T
-
Q
Q
G
P
A
E
E
L
N
K
T
W
Q
T
Q
P
A
L
L
T
A
S
V
A
----
L
Y
R
V
-
W
--
Q
Q
-
Q
-
G
-
G
----
K
A
----
P
A
M
------
M
-
A
G
H
S
L
G
E
Y
S
A
L
V
C
A
G
V
I
D
F
A
D
A
V
R
L
V
E
M
R
G
K
F
M
Q
E
A
V
P
-
E
G
T
G
A
M
A
A
I
I
G
L
D
D
A
S
I
A
K
A
C
E
E
A
A
-
E
G
Q
V
V
S
P
---
V
N
F
N
S
P
G
Q
V
V
I
A
G
H
K
E
A
V
E
R
A
G
A
A
C
K
A
A
G
A
K
R
A
L
P
L
P
V
S
V
P
S
H
C
A
L
M
K
P
A
A
D
K
L
A
V
E
L
A
K
I
T
F
N
A
P
T
V
P
V
V
N
N
V
D
V
K
C
E
T
N
G
D
A
I
R
D
A
L
V
R
Q
L
Y
N
P
V
Q
W
T
K
S
V
E
Y
M
A
A
Q
G
V
E
H
L
Y
E
V
G
P
G
K
V
L
T
G
L
T
K
R
I
---
V
D
T
L
T
A
S
A
L
N
E
P
S
A
M
A
A
A
L
E
--
3
PsiBlast_PDB
87.86
44%
-95
- C1 -
3EZO
-
?
A:
[1-300]
--
K
F
A
F
V
F
P
G
Q
G
S
Q
S
V
G
M
-
L
N
A
F
A
D
V
A
V
V
R
E
T
--
L
D
E
A
S
D
A
L
G
Q
D
I
G
K
L
I
-
A
D
G
P
A
D
E
L
N
L
T
T
N
T
Q
P
V
M
L
T
A
A
Y
A
----
C
Y
R
A
-
W
--
Q
Q
-
A
-
G
G
A
----
Q
P
----
S
-
I
------
V
-
A
G
H
S
L
G
E
Y
T
A
L
V
A
A
G
A
I
A
F
R
D
A
L
P
L
V
R
F
R
A
Q
A
M
Q
T
A
V
P
-
V
G
V
G
G
M
A
A
I
L
G
L
D
D
D
T
V
R
A
V
C
A
E
A
S
A
T
G
-
V
V
E
A
---
V
N
F
N
A
P
A
Q
V
V
I
A
G
T
K
A
G
I
E
K
A
C
E
I
A
K
E
K
G
A
K
R
A
L
P
L
P
V
S
A
P
F
H
S
S
L
L
K
P
A
S
D
K
L
R
E
Y
L
A
G
V
D
V
K
A
P
K
I
S
V
V
N
N
I
D
V
A
V
V
S
D
P
A
A
I
K
D
A
L
V
R
Q
A
A
G
P
V
R
W
V
E
C
V
Q
H
I
A
R
E
G
V
T
H
V
I
E
C
G
P
G
K
V
L
A
G
L
T
K
R
I
D
G
N
L
V
G
A
S
V
F
D
P
A
S
L
----------
5
PsiBlast_PDB
87.79
45%
-90
- C1 -
1MLA
-
FABD_ECOLI
A:
[3-307]
--
Q
F
A
F
V
F
P
G
Q
G
S
Q
T
V
G
M
L
A
D
M
A
A
S
Y
P
I
V
E
E
T
--
F
A
E
A
S
A
A
L
G
Y
D
L
W
A
L
T
-
Q
Q
G
P
A
E
E
L
N
K
T
W
Q
T
Q
P
A
L
L
T
A
S
V
A
----
L
Y
R
V
-
W
--
Q
Q
-
Q
-
G
-
G
----
K
A
----
P
A
M
------
M
-
A
G
H
S
L
G
E
Y
S
A
L
V
C
A
G
V
I
D
F
A
D
A
V
R
L
V
E
M
R
G
K
F
M
Q
E
A
V
P
-
E
G
T
G
A
M
A
A
I
I
G
L
D
D
A
S
I
A
K
A
C
E
E
A
A
-
E
G
Q
V
V
S
P
---
V
N
F
N
S
P
G
Q
V
V
I
A
G
H
K
E
A
V
E
R
A
G
A
A
C
K
A
A
G
A
K
R
A
L
P
L
P
V
S
V
P
S
H
C
A
L
M
K
P
A
A
D
K
L
A
V
E
L
A
K
I
T
F
N
A
P
T
V
P
V
V
N
N
V
D
V
K
C
E
T
N
G
D
A
I
R
D
A
L
V
R
Q
L
Y
N
P
V
Q
W
T
K
S
V
E
Y
M
A
A
Q
G
V
E
H
L
Y
E
V
G
P
G
K
V
L
T
G
L
T
K
R
I
---
V
D
T
L
T
A
S
A
L
N
E
P
S
A
M
A
A
A
L
---
9
PsiBlast_PDB
87.75
45%
-89
- C1 -
2G2Z
2
FABD_ECOLI
A:
[2-307]
--
Q
F
A
F
V
F
P
G
Q
G
S
Q
T
V
G
M
L
A
D
M
A
A
S
Y
P
I
V
E
E
T
--
F
A
E
A
S
A
A
L
G
Y
D
L
W
A
L
T
-
Q
Q
G
P
A
E
E
L
N
K
T
W
Q
T
Q
P
A
L
L
T
A
S
V
A
----
L
Y
R
V
-
W
--
Q
Q
-
Q
-
G
-
G
----
K
A
----
P
A
M
------
M
-
A
G
H
S
L
G
E
Y
S
A
L
V
C
A
G
V
I
D
F
A
D
A
V
R
L
V
E
M
R
G
K
F
M
Q
E
A
V
P
-
E
G
T
G
A
M
A
A
I
I
G
L
D
D
A
S
I
A
K
A
C
E
E
A
A
-
E
G
Q
V
V
S
P
---
V
N
F
N
S
P
G
Q
V
V
I
A
G
H
K
E
A
V
E
R
A
G
A
A
C
K
A
A
G
A
K
R
A
L
P
L
P
V
S
V
P
S
H
C
A
L
M
K
P
A
A
D
K
L
A
V
E
L
A
K
I
T
F
N
A
P
T
V
P
V
V
N
N
V
D
V
K
C
E
T
N
G
D
A
I
R
D
A
L
V
R
Q
L
Y
N
P
V
Q
W
T
K
S
V
E
Y
M
A
A
Q
G
V
E
H
L
Y
E
V
G
P
G
K
V
L
T
G
L
T
K
R
I
---
V
D
T
L
T
A
S
A
L
N
E
P
S
A
M
A
A
A
L
E
--
26
HHSearch
87.61
45%
-92
- C1 -
1MLA
-
FABD_ECOLI
A:
[3-298]
--
Q
F
A
F
V
F
P
G
Q
G
S
Q
T
V
G
M
L
A
D
M
A
A
S
Y
P
I
V
E
E
T
--
F
A
E
A
S
A
A
L
G
Y
D
L
W
A
L
T
-
Q
Q
G
P
A
E
E
L
N
K
T
W
Q
T
Q
P
A
L
L
T
A
S
V
A
----
L
Y
R
V
-
W
--
Q
Q
-
Q
G
G
-
K
----
A
P
----
A
-
M
------
M
-
A
G
H
S
L
G
E
Y
S
A
L
V
C
A
G
V
I
D
F
A
D
A
V
R
L
V
E
M
R
G
K
F
M
Q
E
A
V
P
-
E
G
T
G
A
M
A
A
I
I
G
L
D
D
A
S
I
A
K
A
C
E
E
A
A
-
E
G
Q
V
V
S
P
---
V
N
F
N
S
P
G
Q
V
V
I
A
G
H
K
E
A
V
E
R
A
G
A
A
C
K
A
A
G
A
K
R
A
L
P
L
P
V
S
V
P
S
H
C
A
L
M
K
P
A
A
D
K
L
A
V
E
L
A
K
I
T
F
N
A
P
T
V
P
V
V
N
N
V
D
V
K
C
E
T
N
G
D
A
I
R
D
A
L
V
R
Q
L
Y
N
P
V
Q
W
T
K
S
V
E
Y
M
A
A
Q
G
V
E
H
L
Y
E
V
G
P
G
K
V
L
T
G
L
T
K
R
I
V
D
T
L
T
A
S
A
L
N
---------------
8
PsiBlast_PDB
87.06
45%
-90
- C1 -
2G2Y
1
FABD_ECOLI
A:
[2-306]
--
Q
F
A
F
V
F
P
G
Q
G
S
Q
T
V
G
M
L
A
D
M
A
A
S
Y
P
I
V
E
E
T
--
F
A
E
A
S
A
A
L
G
Y
D
L
W
A
L
T
-
Q
Q
G
P
A
E
E
L
N
K
T
W
Q
T
Q
P
A
L
L
T
A
S
V
A
----
L
Y
R
V
-
W
--
Q
Q
-
Q
-
G
-
G
----
K
A
----
P
A
M
------
M
-
A
G
H
S
L
G
E
Y
S
A
L
V
C
A
G
V
I
D
F
A
D
A
V
R
L
V
E
M
R
G
K
F
M
Q
E
A
V
P
-
E
G
T
G
A
M
A
A
I
I
G
L
D
D
A
S
I
A
K
A
C
E
E
A
A
-
E
G
Q
V
V
S
P
---
V
N
F
N
S
P
G
Q
V
V
I
A
G
H
K
E
A
V
E
R
A
G
A
A
C
K
A
A
G
A
K
R
A
L
P
L
P
V
S
V
P
S
H
C
A
L
M
K
P
A
A
D
K
L
A
V
E
L
A
K
I
T
F
N
A
P
T
V
P
V
V
N
N
V
D
V
K
C
E
T
N
G
D
A
I
R
D
A
L
V
R
Q
L
Y
N
P
V
Q
W
T
K
S
V
E
Y
M
A
A
Q
G
V
E
H
L
Y
E
V
G
P
G
K
V
L
T
G
L
T
K
R
I
---
V
D
T
L
T
A
S
A
L
N
E
P
S
A
M
A
A
A
L
---
21
PsiBlast_CBE
86.63
43%
-92
- C1 -
3QAT
2
?
B:
[8-311]
----
A
F
T
F
P
G
Q
G
S
Q
L
I
G
M
G
K
V
L
T
E
Q
F
V
A
A
R
M
V
--
F
E
E
V
D
D
A
L
S
E
K
L
S
D
I
I
-
F
E
G
P
A
D
V
L
T
L
T
A
N
A
Q
P
A
L
M
A
V
S
M
A
----
V
I
R
V
-
M
--
E
Q
-
L
-
G
-
L
NVEK
K
V
----
K
-
F
------
V
-
A
G
H
S
L
G
E
Y
S
A
L
C
A
A
G
T
F
S
L
T
D
T
A
R
L
L
R
I
R
G
N
A
M
Q
A
A
V
A
-
V
G
E
G
S
M
A
A
L
I
G
L
D
E
K
D
V
E
E
I
C
E
I
V
A
E
E
G
-
L
C
Q
I
---
A
N
D
N
G
G
G
Q
I
V
I
S
G
E
A
K
A
V
E
T
A
V
E
V
A
S
Q
K
G
A
K
R
A
V
L
L
P
V
S
A
P
F
H
S
A
L
M
Q
P
A
A
N
A
M
K
N
A
L
L
T
V
N
K
T
A
P
I
V
P
L
I
A
N
V
S
V
I
P
E
S
D
P
E
R
I
V
S
L
L
V
Q
Q
V
T
G
R
V
R
W
R
E
T
I
E
W
I
S
A
N
G
V
N
T
L
F
E
I
G
S
G
K
V
L
T
G
L
A
R
R
I
N
K
D
I
K
A
L
T
V
G
T
A
E
E
I
E
A
--------
2
PsiBlast_PDB
86.26
43%
-92
- C1 -
3QAT
2
?
A:
[8-311]
----
A
F
T
F
P
G
Q
G
S
Q
L
I
G
M
G
K
V
L
T
E
Q
F
V
A
A
R
M
V
--
F
E
E
V
D
D
A
L
S
E
K
L
S
D
I
I
-
F
E
G
P
A
D
V
L
T
L
T
A
N
A
Q
P
A
L
M
A
V
S
M
A
----
V
I
R
V
-
M
--
E
Q
-
L
-
G
-
L
NVEK
K
V
----
K
-
F
------
V
-
A
G
H
S
L
G
E
Y
S
A
L
C
A
A
G
T
F
S
L
T
D
T
A
R
L
L
R
I
R
G
N
A
M
Q
A
A
V
A
-
V
G
E
G
S
M
A
A
L
I
G
L
D
E
K
D
V
E
E
I
C
E
I
V
A
E
E
G
-
L
C
Q
I
---
A
N
D
N
G
G
G
Q
I
V
I
S
G
E
A
K
A
V
E
T
A
V
E
V
A
S
Q
K
G
A
K
R
A
V
L
L
P
V
S
A
P
F
H
S
A
L
M
Q
P
A
A
N
A
M
K
N
A
L
L
T
V
N
K
T
A
P
I
V
P
L
I
A
N
V
S
V
I
P
E
S
D
P
E
R
I
V
S
L
L
V
Q
Q
V
T
G
R
V
R
W
R
E
T
I
E
W
I
S
A
N
G
V
N
T
L
F
E
I
G
S
G
K
V
L
T
G
L
A
R
R
I
N
K
D
I
K
A
L
T
V
G
T
A
E
E
I
E
A
--------
11
PsiBlast_PDB
86.03
43%
-92
- C1 -
3IM8
1
?
A:
[3-300]
--
K
T
A
F
L
F
A
G
Q
G
A
Q
Y
L
G
M
G
R
D
F
Y
D
Q
Y
P
I
V
K
E
T
--
I
D
R
A
S
Q
V
L
G
Y
D
L
R
Y
L
I
D
T
E
E
--
D
K
L
N
Q
T
R
Y
T
Q
P
A
I
L
A
T
S
V
A
----
I
Y
R
L
-
L
--
Q
E
-
K
-
G
-
Y
----
Q
P
----
D
-
M
------
V
-
A
G
L
S
L
G
E
Y
S
A
L
V
A
S
G
A
L
D
F
E
D
A
V
A
L
V
A
K
R
G
A
Y
M
E
E
A
A
P
-
A
D
S
G
K
M
V
A
V
L
N
T
P
V
E
V
I
E
E
A
C
Q
K
A
S
E
L
G
-
V
V
T
P
---
A
N
Y
N
T
P
A
Q
I
V
I
A
G
E
V
V
A
V
D
R
A
V
E
L
L
Q
E
A
G
A
K
R
L
I
P
L
K
V
S
G
P
F
H
T
S
L
L
E
P
A
S
Q
K
L
A
E
T
L
A
Q
V
S
F
S
D
F
T
C
P
L
V
G
N
T
E
A
A
-
V
M
Q
K
E
D
I
A
Q
L
L
T
R
Q
V
K
E
P
V
R
F
Y
E
S
I
G
V
M
Q
E
A
G
I
S
N
F
I
E
I
G
P
G
K
V
L
S
G
F
V
K
K
I
D
Q
T
A
H
L
A
H
V
E
D
Q
A
S
L
----------
16
PsiBlast_PDB
85.89
38%
-94
- C1 -
3TQE
3
?
A:
[8-299]
---
F
A
F
V
F
P
G
Q
G
S
Q
H
L
G
M
L
A
E
L
G
L
Q
Q
P
I
V
L
E
T
--
F
Q
Q
A
S
S
A
L
A
Y
D
L
W
A
L
V
-
Q
H
G
P
Q
E
R
L
D
Q
T
Q
F
T
Q
P
A
L
L
T
A
D
V
A
----
I
F
R
C
-
W
--
E
A
-
L
-
G
G
P
----
K
P
----
Q
-
V
------
M
-
A
G
H
S
L
G
E
Y
A
A
L
V
C
A
G
A
L
K
F
E
E
A
V
K
L
V
E
K
R
G
Q
Y
M
Q
E
A
V
P
-
V
G
E
G
A
M
G
A
I
I
G
L
N
E
A
E
I
E
S
I
C
E
N
A
A
L
-
G
Q
V
V
Q
P
---
A
N
L
N
S
T
D
Q
T
V
I
S
G
H
S
E
A
V
D
R
A
L
N
M
A
K
T
E
G
A
K
I
A
K
R
I
P
V
S
V
P
S
H
C
P
L
M
Q
P
A
A
D
R
L
A
Q
D
I
A
K
I
S
I
D
S
P
K
V
P
V
I
H
N
V
D
V
V
D
H
N
E
A
N
I
I
R
G
A
L
I
K
Q
L
V
R
P
V
R
W
V
E
T
I
K
Y
I
E
E
Q
G
I
K
V
F
M
E
C
G
P
D
N
K
L
A
G
L
I
K
R
I
D
R
Q
S
E
I
L
------------------
12
PsiBlast_PDB
85.77
44%
-87
- C1 -
3H0P
1
FABD_SALTY
A:
[5-296]
-
T
Q
F
A
F
V
F
P
G
Q
G
S
Q
S
V
G
M
L
A
E
M
A
A
N
Y
P
I
V
E
E
T
--
F
A
E
A
S
A
A
L
G
Y
D
L
W
A
L
T
-
Q
Q
G
P
A
E
E
L
N
K
T
W
Q
T
Q
P
A
L
L
T
A
S
V
A
----
L
W
R
V
-
W
--
Q
Q
-
Q
-
G
-
G
----
K
M
----
P
-
A
------
L
M
A
G
H
S
L
G
E
Y
S
A
L
V
C
A
G
V
I
N
F
A
D
A
V
R
L
V
E
M
R
G
K
F
M
Q
E
A
V
P
-
E
G
T
G
G
M
S
A
I
I
G
L
D
D
A
S
I
A
K
A
C
E
E
-
S
A
E
G
Q
V
V
S
P
---
V
N
F
N
S
P
G
Q
V
V
I
A
G
H
K
E
A
V
E
R
A
G
A
A
C
K
A
A
G
A
K
R
A
L
P
L
P
V
S
V
P
S
H
C
A
L
M
K
P
A
A
D
K
L
A
V
E
L
A
K
I
T
F
S
A
P
T
V
P
V
V
N
N
V
D
V
K
C
E
T
D
A
A
A
I
R
D
A
L
V
R
Q
L
Y
N
P
V
Q
W
T
K
S
V
E
F
I
A
A
Q
G
V
E
H
L
Y
E
V
G
P
G
K
V
L
T
G
L
T
K
R
I
V
D
T
L
T
--------------------
33
HHSearch
84.49
39%
-91
- C1 -
3K89
1
?
A:
[4-312]
-
S
T
L
A
F
V
F
P
G
Q
G
S
Q
S
L
G
M
L
A
E
L
S
E
L
H
P
Q
I
R
E
T
--
F
A
E
A
S
E
G
A
G
V
D
L
W
A
L
S
-
Q
G
G
P
E
E
M
L
N
R
T
E
Y
T
Q
P
A
L
L
A
A
G
V
A
----
V
W
R
L
-
W
--
T
A
Q
R
-
G
-
Q
----
R
P
----
A
-
L
------
L
-
A
G
H
S
L
G
E
Y
T
A
L
V
A
A
G
V
L
S
L
H
D
G
A
H
L
V
R
L
R
G
Q
F
M
Q
A
A
A
P
-
A
G
V
G
A
M
A
A
V
L
G
A
E
D
A
V
V
L
E
V
C
A
E
A
A
-
G
S
Q
V
V
V
P
---
A
N
F
N
S
P
G
Q
I
V
I
G
G
D
A
A
A
V
D
R
A
L
A
L
L
A
E
R
G
V
R
K
A
V
K
L
A
V
S
V
P
S
H
T
P
L
M
R
D
A
A
N
Q
L
G
E
A
M
A
G
L
S
W
H
A
P
Q
I
P
V
V
Q
N
V
D
A
R
V
H
D
G
S
A
A
I
R
Q
A
L
V
E
Q
L
Y
L
P
V
Q
W
T
G
C
V
Q
A
L
A
S
Q
G
I
T
R
I
A
E
C
G
P
G
K
V
L
S
G
L
I
K
R
I
D
K
S
L
D
A
R
P
L
A
T
P
A
D
Y
A
G
A
L
D
A
W
---
4
PsiBlast_PDB
84.31
43%
-80
- C1 -
3HJV
18
?
A:
[7-311]
-
S
K
F
A
I
V
F
P
G
Q
G
S
Q
A
V
G
M
L
A
D
L
A
E
Q
Y
A
V
V
K
Q
T
--
F
A
E
A
S
E
V
L
G
Y
D
L
W
A
L
V
-
Q
D
G
P
V
E
D
L
N
Q
T
F
R
T
Q
P
A
L
L
A
A
S
V
A
----
I
W
R
V
-
W
--
Q
Q
-
L
-
G
-
L
----
E
Q
----
P
-
A
------
V
L
A
G
H
S
L
G
E
Y
S
A
L
V
C
A
G
V
I
D
F
K
Q
A
I
K
L
V
E
L
R
G
Q
L
M
Q
Q
A
V
P
-
A
G
T
G
A
M
Y
A
I
I
G
L
E
D
E
A
-
I
A
K
A
C
A
D
A
A
Q
G
E
V
V
S
P
---
V
N
F
N
S
P
G
Q
V
V
I
A
G
Q
K
D
A
V
E
R
A
G
V
L
C
K
E
A
G
A
K
R
A
L
P
L
P
V
S
V
P
S
H
C
A
L
M
K
P
A
A
D
E
L
A
K
T
L
A
E
L
E
F
N
A
P
Q
I
P
V
I
N
N
V
D
V
V
A
E
T
D
P
V
K
I
K
D
A
L
I
R
Q
L
Y
S
P
V
R
W
T
E
C
V
E
Q
M
S
A
Q
G
V
E
K
L
I
E
M
G
P
G
K
V
L
T
G
L
T
K
R
I
V
K
T
L
E
G
V
A
V
N
D
V
A
S
L
D
A
V
-------
13
PsiBlast_PDB
79.33
41%
-89
- C1 -
3K89
1
?
A:
[4-294]
-
S
T
L
A
F
V
F
P
G
Q
G
S
Q
S
L
G
M
L
A
E
L
S
E
L
H
P
Q
I
R
E
T
--
F
A
E
A
S
E
G
A
G
V
D
L
W
A
L
S
-
Q
G
G
P
E
E
M
L
N
R
T
E
Y
T
Q
P
A
L
L
A
A
G
V
A
----
V
W
R
L
-
W
--
T
A
-
Q
R
G
-
Q
----
R
P
----
A
-
L
------
L
-
A
G
H
S
L
G
E
Y
T
A
L
V
A
A
G
V
L
S
L
H
D
G
A
H
L
V
R
L
R
G
Q
F
M
Q
A
A
A
P
-
A
G
V
G
A
M
A
A
V
L
G
A
E
----
D
A
V
V
L
E
V
C
A
E
A
A
G
S
Q
V
V
V
P
A
N
F
N
S
P
G
Q
I
V
I
G
G
D
A
A
A
V
D
R
A
L
A
L
L
A
E
R
G
V
R
K
A
V
K
L
A
V
S
V
P
S
H
T
P
L
M
R
D
A
A
N
Q
L
G
E
A
M
A
G
L
S
W
H
A
P
Q
I
P
V
V
Q
N
V
D
A
R
V
H
D
G
S
A
A
I
R
Q
A
L
V
E
Q
L
Y
L
P
V
Q
W
T
G
C
V
Q
A
L
A
S
Q
G
I
T
R
I
A
E
C
G
P
G
K
V
L
S
G
L
I
K
R
I
D
K
S
L
---------------------
14
PsiBlast_PDB
76.87
41%
-90
- C1 -
3R97
1
?
A:
[4-294]
-
S
T
L
A
F
V
F
P
G
Q
G
S
Q
S
L
G
M
L
A
E
L
S
E
L
H
P
Q
I
R
E
T
--
F
A
E
A
S
E
G
A
G
V
D
L
W
A
L
S
-
Q
G
G
P
E
E
M
L
N
R
T
E
Y
T
Q
P
A
L
L
A
A
G
V
A
----
V
W
R
L
-
W
--
T
A
-
Q
R
G
-
Q
----
R
P
----
A
-
L
------
L
-
A
G
H
S
L
G
E
Y
T
A
L
V
A
A
G
V
L
S
L
H
D
G
A
H
L
V
R
L
R
G
Q
F
M
Q
A
A
A
P
-
A
G
V
G
A
M
A
A
V
L
G
A
E
----
D
A
V
V
L
E
V
C
A
E
A
A
G
S
Q
V
V
V
P
A
N
F
N
S
P
G
Q
I
V
I
G
G
D
A
A
A
V
D
R
A
L
A
L
L
A
E
R
G
V
R
K
A
V
K
L
A
V
S
V
P
S
H
T
P
L
M
R
D
A
A
N
Q
L
G
E
A
M
A
G
L
S
W
H
A
P
Q
I
P
V
V
Q
N
V
D
A
R
V
H
D
G
S
A
A
I
R
Q
A
L
V
E
Q
L
Y
L
P
V
Q
W
T
G
C
V
Q
A
L
A
S
Q
G
I
T
R
I
A
E
C
G
P
G
K
V
L
S
G
L
I
K
R
I
D
K
S
L
---------------------
32
HHSearch
74.44
30%
-78
- C1 -
1NM2
3
?
A:
[1-310]
-
H
M
L
V
L
V
A
P
G
Q
G
A
Q
T
P
G
F
L
T
D
W
L
A
L
-
P
G
A
A
D
R
--
V
A
A
W
S
D
A
I
G
L
D
L
A
H
F
G
-
T
K
A
D
A
D
E
I
R
D
T
S
V
A
Q
P
L
L
V
A
A
G
I
L
----
S
A
A
A
-
L
G
T-----
G
-
F
----
T
P
----
G
-
A
------
V
-
A
G
H
S
V
G
E
I
T
A
A
V
F
A
G
V
L
D
D
T
A
A
L
S
L
V
R
R
R
G
L
A
M
A
E
A
A
A
V
T
-
E
T
G
M
S
A
L
L
G
G
D
P
E
V
S
V
A
H
L
E
-----
R
L
G
L
T
P
---
A
N
V
N
G
A
G
Q
I
V
A
A
G
T
M
E
Q
L
A
A
L
N
E
D
K
P
E
G
V
R
-
K
V
V
P
L
K
V
A
G
A
F
H
T
R
H
M
A
P
A
V
D
K
L
A
E
A
A
K
A
L
T
P
A
D
P
K
V
T
Y
V
S
N
K
D
G
R
A
V
A
S
G
T
E
V
L
D
R
L
V
G
Q
V
A
N
P
V
R
W
D
L
C
M
E
T
F
K
E
L
G
V
T
A
I
I
E
V
C
P
G
G
T
L
T
G
L
A
K
R
A
L
P
G
V
K
T
L
A
L
K
T
P
D
D
L
D
A
A
R
E
L
----
22
PsiBlast_CBE
69.21
31%
-78
- C1 -
1NM2
3
?
A:
[3-288]
---
L
V
L
V
A
P
G
Q
G
A
Q
T
P
G
F
L
T
D
W
L
A
L
P
G
A
A
D
R
V
A
A
W
S
D
A
---
I
G
L
D
L
A
H
F
G
-
T
K
A
D
A
D
E
I
R
D
T
S
V
A
Q
P
L
L
V
A
A
G
I
L
----
S
A
A
A
-
L
--
G
T
-------------------GFTPG
A
V
-
A
G
H
S
V
G
E
I
T
A
A
V
F
A
G
V
L
D
D
T
A
A
L
S
L
V
R
R
R
G
L
A
M
A
E
A
A
A
-
V
T
E
T
G
M
S
A
L
L
G
G
D
P
E
V
S
V
A
H
L
E
R
L
-----
G
L
T
P
---
A
N
V
N
G
A
G
Q
I
V
A
A
G
T
M
E
Q
L
A
A
L
N
E
D
-
K
P
E
G
V
R
K
V
V
P
L
K
V
A
G
A
F
H
T
R
H
M
A
P
A
V
D
K
L
A
E
A
A
K
A
L
T
P
A
D
P
K
V
T
Y
V
S
N
K
D
G
R
A
V
A
S
G
T
E
V
L
D
R
L
V
G
Q
V
A
N
P
V
R
W
D
L
C
M
E
T
F
K
E
L
G
V
T
A
I
I
E
V
C
P
G
G
T
L
T
G
L
A
K
R
--------------------------
35
HHSearch
67.67
30%
-75
- C1 -
2QC3
1
FABD_MYCTU
A:
[1-302]
-
H
M
I
A
L
L
A
P
G
Q
G
S
Q
T
E
G
M
L
S
P
W
L
Q
-
L
P
G
A
A
D
Q
--
I
A
A
W
S
K
A
A
D
L
D
L
A
R
L
G
-
T
T
A
S
T
E
E
I
T
D
T
A
V
A
Q
P
L
I
V
A
A
T
L
L
A
H
Q
E
L
A
R
R
-
C
--
V
L
-
A
-
G
------
K
D
----
V
-
I
------
V
-
A
G
H
S
V
G
E
I
A
A
Y
A
I
A
G
V
I
A
A
D
D
A
V
A
L
A
A
T
R
G
A
E
M
A
K
A
C
A
T
E
-
P
T
G
M
S
A
V
L
G
G
D
E
T
E
V
L
S
R
L
E
Q
-----
L
D
L
V
P
---
A
N
R
N
A
A
G
Q
I
V
A
A
G
R
L
T
A
L
E
K
L
A
E
D
P
P
A
-
K
A
-
R
V
R
A
L
G
V
A
G
A
F
H
T
E
F
M
A
P
A
L
D
G
F
A
A
A
A
A
N
I
A
T
A
D
P
T
A
T
L
L
S
N
R
D
G
K
P
V
T
S
A
A
A
A
M
D
T
L
V
S
Q
L
T
Q
P
V
R
W
D
L
C
T
A
T
L
R
E
H
T
V
T
A
I
V
E
F
P
P
A
G
T
L
S
G
I
A
K
R
E
L
R
G
V
P
A
R
A
V
K
S
P
A
D
L
D
E
L
A
N
-----