@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1901: (2016-03-30 )
MLIIRNKQELKEVILKQKQANKTIGFVPTMGFLHEGHMTLVSHARKESDFVVMSVFVNPTQFGPNEDFDAYPRDEAHDAKLAEEGGVDILFVPTVEEIYPTELSTKLHVDKRVSVLDGADREGHFDGVVTVLTKLFHLVSPDNAYFGQKDAQQVAVVSGLVEDYFFPVNLRIIATVREADGLAKSSRNVYLTEKERKEAPVIHEALQLGRKLIESGETNQAKIVQMMTEKINEQTSHELIAYLAIYSYPEFTPVTDWSKGIIIAAAVKYSKARLIDNELINVKRR
Atome Classification :
(108 SA)
.........10........20........30........40.....-.-..50........60........70........80........90........100--....--..--...110....-..-...120.......130.......140.......150.......160.......170.......180.......190.......200-----.......-..210...-....220.......230-.......240.......250...----.----------.----.-.260.......270.......280...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
L
I
IR
N
K
Q
E
L
K
E
V
I
L
K
Q
KQANKTIGFVP
T
M
G
F
LHEG
H
M
T
L
V
S
HARK-E-S
D
F
V
V
M
S
V
F
VNPTQFGPNEDFDAYPRDEAHD
A
K
L
AEEGG
V
D
I
L
F
VP
T
V
E
E
IYP----TEL
S
--
T
K
--
L
H
V
D
--
K
R
V
S
-VL-DGADREGHF
D
G
V
V
T
V
L
T
K
L
F
H
LVSPDNAYFGQ
K
D
A
Q
Q
V
A
V
V
S
G
L
V
E
D
Y
F
FP
V
N
L
R
I
I
A
T
VREADGLAKSSR
N
V
Y
L
T
E
K
ERKEA
P
-------
V
I
H
E
A
L
Q
-
L
G
R
K
L
I
ES-GET
N
Q
A
K
I
V
Q
M
M
T
E
KIN-E
Q
T
S
H
E
L
I
A
Y
L
A
I
YSYPEFTPVT----D----------W----S-K
G
I
I
I
A
A
A
V
KY
S
K
A
RLIDN
E
L
INVKRR
22
PsiBlast_CBE
96.56
49%
-105
- C5 -
2X3F
1
PANC_STAAR
B:
[6-283]
--
L
I
T
T
V
K
E
M
Q
H
I
V
K
A
A
K
R
S
G
T
T
I
G
F
I
P
T
M
G
A
L
H
D
G
H
L
T
M
V
R
E
S
V
S
-
T
-
N
D
I
T
V
V
S
V
F
V
N
P
L
Q
F
G
P
N
E
D
F
-
A
Y
P
R
Q
I
D
K
D
L
E
L
V
S
E
V
G
A
D
I
V
F
H
P
A
V
E
D
M
Y
P
----
G
E
L
G
--
I
D
--
V
K
V
G
--
P
L
A
D
-
V
L
-
E
G
A
K
R
P
G
H
F
D
G
V
V
T
V
V
N
K
L
F
N
I
V
M
P
D
Y
A
Y
F
G
K
K
D
A
Q
Q
L
A
I
V
E
Q
M
V
K
D
F
N
H
A
V
E
I
I
G
I
D
I
V
R
E
A
D
G
L
A
K
S
S
R
N
V
Y
L
T
E
Q
E
R
Q
E
A
V
-------
H
L
S
K
S
L
L
-
L
A
Q
A
L
Y
Q
D
-
G
E
R
Q
S
K
V
I
I
D
K
V
T
Q
Y
L
E
-
S
H
I
S
G
R
-
I
E
E
V
A
V
Y
S
Y
P
Q
L
V
E
Q
H
----
E
----------
I
----
T
-
G
R
I
F
I
S
L
A
V
K
F
S
K
A
R
L
I
D
N
I
I
I
G
----
115
HHSearch
95.54
46%
-111
- C5 -
2EJC
22
PANC_THEMA
A:
[1-280]
M
R
I
I
E
T
I
E
E
M
K
K
F
S
E
E
M
R
E
K
K
K
T
I
G
F
V
P
T
M
G
Y
L
H
E
G
H
L
S
L
V
R
R
A
R
A
-
E
-
N
D
V
V
V
V
S
I
F
V
N
P
T
Q
F
G
P
N
E
D
Y
E
R
Y
P
R
D
F
E
R
D
R
K
L
L
E
K
E
N
V
D
C
I
F
H
P
S
V
E
E
M
Y
P
----
P
D
F
S
--
T
Y
--
V
E
E
T
--
K
L
S
K
-
H
L
-
C
G
R
S
R
P
G
H
F
R
G
V
C
T
V
V
T
K
L
F
N
I
V
K
P
H
R
A
Y
F
G
Q
K
D
A
Q
Q
F
R
V
L
R
R
M
V
R
D
L
N
M
D
V
E
M
I
E
C
P
I
V
R
E
P
D
G
L
A
M
S
S
R
N
V
Y
L
S
P
E
E
R
Q
Q
A
L
-------
S
L
Y
Q
S
L
K
-
I
A
E
N
L
Y
L
N
-
G
E
R
D
A
E
K
I
K
E
E
M
I
K
H
L
S
R
F
D
-
K
V
-
K
I
D
Y
V
E
I
V
D
E
E
T
L
E
P
V
E
----
K
----------
I
----
D
-
R
K
V
I
V
A
V
A
A
W
V
G
N
A
R
L
I
D
N
T
I
L
G
----
111
HHSearch
95.02
49%
-102
- C5 -
3AG6
7
PANC_STAA8
A:
[2-282]
T
K
L
I
T
T
V
K
E
M
Q
H
I
V
K
A
A
K
R
S
G
T
T
I
G
F
I
P
T
M
G
A
L
H
D
G
H
L
T
M
V
R
E
S
V
S
-
T
-
N
D
I
T
I
V
S
V
F
V
N
P
L
Q
F
G
P
N
E
D
F
D
A
Y
P
R
Q
I
D
K
D
L
E
L
V
S
E
V
G
A
D
I
V
F
H
P
A
V
E
D
M
Y
P
----
G
E
L
G
--
I
D
--
V
K
V
G
--
P
L
A
D
-
V
L
-
E
G
A
K
R
P
G
H
F
D
G
V
V
T
V
V
N
K
L
F
N
I
V
M
P
D
Y
A
Y
F
G
K
K
D
A
Q
Q
L
A
I
V
E
Q
M
V
K
D
F
N
H
A
V
E
I
I
G
I
D
I
V
R
E
A
D
G
L
A
K
S
S
R
N
V
Y
L
T
E
Q
E
R
Q
E
A
V
-------
H
L
S
K
S
L
L
-
L
A
Q
A
L
Y
Q
D
-
G
E
R
Q
S
K
V
I
I
D
R
V
T
E
Y
L
E
S
H
I
-
S
E
-
R
I
E
E
V
A
V
Y
S
Y
P
Q
L
V
E
Q
H
----
E
----------
I
----
T
-
G
R
I
F
I
S
L
A
V
K
F
S
K
A
R
L
I
D
N
I
I
I
G
A
---
3
PsiBlast_PDB
94.98
49%
-102
- C5 -
2X3F
2
PANC_STAAR
A:
[6-283]
--
L
I
T
T
V
K
E
M
Q
H
I
V
K
A
A
K
R
S
G
T
T
I
G
F
I
P
T
M
G
A
L
H
D
G
H
L
T
M
V
R
E
S
V
S
-
T
-
N
D
I
T
V
V
S
V
F
V
N
P
L
Q
F
G
P
N
E
D
F
D
A
Y
P
R
Q
I
D
K
D
L
E
L
V
S
E
V
G
A
D
I
V
F
H
P
A
V
E
D
M
Y
P
----
G
E
L
G
--
I
D
--
V
K
V
G
--
P
L
A
D
-
V
L
-
E
G
A
K
R
P
G
H
F
D
G
V
V
T
V
V
N
K
L
F
N
I
V
M
P
D
Y
A
Y
F
G
K
K
D
A
Q
Q
L
A
I
V
E
Q
M
V
K
D
F
N
H
A
V
E
I
I
G
I
D
I
V
R
E
A
D
G
L
A
K
S
S
R
N
V
Y
L
T
E
Q
E
R
Q
E
A
V
-------
H
L
S
K
S
L
L
-
L
A
Q
A
L
Y
Q
D
-
G
E
R
Q
S
K
V
I
I
D
K
V
T
Q
Y
L
E
-
S
H
I
S
G
R
-
I
E
E
V
A
V
Y
S
Y
P
Q
L
V
E
Q
H
----
E
----------
I
----
T
-
G
R
I
F
I
S
L
A
V
K
F
S
K
A
R
L
I
D
N
I
I
I
G
----
4
PsiBlast_PDB
94.82
46%
-111
- C5 -
2EJC
22
PANC_THEMA
A:
[1-279]
M
R
I
I
E
T
I
E
E
M
K
K
F
S
E
E
M
R
E
K
K
K
T
I
G
F
V
P
T
M
G
Y
L
H
E
G
H
L
S
L
V
R
R
A
R
A
-
E
-
N
D
V
V
V
V
S
I
F
V
N
P
T
Q
F
G
P
N
E
D
Y
E
R
Y
P
R
D
F
E
R
D
R
K
L
L
E
K
E
N
V
D
C
I
F
H
P
S
V
E
E
M
Y
P
----
P
D
F
S
--
T
Y
--
V
E
E
T
--
K
L
S
K
-
H
L
-
C
G
R
S
R
P
G
H
F
R
G
V
C
T
V
V
T
K
L
F
N
I
V
K
P
H
R
A
Y
F
G
Q
K
D
A
Q
Q
F
R
V
L
R
R
M
V
R
D
L
N
M
D
V
E
M
I
E
C
P
I
V
R
E
P
D
G
L
A
M
S
S
R
N
V
Y
L
S
P
E
E
R
Q
Q
A
L
-------
S
L
Y
Q
S
L
K
-
I
A
E
N
L
Y
L
N
-
G
E
R
D
A
E
K
I
K
E
E
M
I
K
H
L
S
--
R
F
D
K
V
K
I
D
Y
V
E
I
V
D
E
E
T
L
E
P
V
E
----
K
----------
I
----
D
-
R
K
V
I
V
A
V
A
A
W
V
G
N
A
R
L
I
D
N
T
I
L
-----
2
PsiBlast_PDB
94.43
49%
-99
- C5 -
3AG6
7
PANC_STAA8
A:
[4-281]
--
L
I
T
T
V
K
E
M
Q
H
I
V
K
A
A
K
R
S
G
T
T
I
G
F
I
P
T
M
G
A
L
H
D
G
H
L
T
M
V
R
E
S
V
S
-
T
-
N
D
I
T
I
V
S
V
F
V
N
P
L
Q
F
G
P
N
E
D
F
D
A
Y
P
R
Q
I
D
K
D
L
E
L
V
S
E
V
G
A
D
I
V
F
H
P
A
V
E
D
M
Y
P
----
G
E
L
G
--
I
D
--
V
K
V
G
--
P
L
A
D
-
V
L
-
E
G
A
K
R
P
G
H
F
D
G
V
V
T
V
V
N
K
L
F
N
I
V
M
P
D
Y
A
Y
F
G
K
K
D
A
Q
Q
L
A
I
V
E
Q
M
V
K
D
F
N
H
A
V
E
I
I
G
I
D
I
V
R
E
A
D
G
L
A
K
S
S
R
N
V
Y
L
T
E
Q
E
R
Q
E
A
V
-------
H
L
S
K
S
L
L
-
L
A
Q
A
L
Y
Q
D
-
G
E
R
Q
S
K
V
I
I
D
R
V
T
E
Y
L
E
-
S
H
I
S
-
E
R
I
E
E
V
A
V
Y
S
Y
P
Q
L
V
E
Q
H
----
E
----------
I
----
T
-
G
R
I
F
I
S
L
A
V
K
F
S
K
A
R
L
I
D
N
I
I
I
G
----
21
PsiBlast_CBE
93.46
49%
-98
- C5 -
3AG6
7
PANC_STAA8
B:
[4-281]
--
L
I
T
T
V
K
E
M
Q
H
I
V
K
A
A
K
R
S
G
T
T
I
G
F
I
P
T
M
G
A
L
H
D
G
H
L
T
M
V
R
E
S
V
S
-
T
-
N
D
I
T
I
V
S
V
F
V
N
P
L
Q
F
G
P
N
E
D
F
D
A
Y
P
R
Q
I
D
K
D
L
E
L
V
S
E
V
G
A
D
I
V
F
H
P
A
V
E
D
M
Y
P
----
G
E
L
G
--
I
D
--
V
K
V
G
--
P
L
A
D
-
V
L
-
E
G
A
K
R
P
G
H
F
D
G
V
V
T
V
V
N
K
L
F
N
I
V
M
P
D
Y
A
Y
F
G
K
K
D
A
Q
Q
L
A
I
V
E
Q
M
V
K
D
F
N
H
A
V
E
I
I
G
I
D
I
V
R
E
A
D
G
L
A
K
S
S
R
N
V
Y
L
T
E
Q
E
R
Q
E
A
V
-------
H
L
S
K
S
L
L
-
L
A
Q
A
L
Y
Q
D
-
G
E
R
Q
S
K
V
I
I
D
R
V
T
E
Y
L
E
-
S
H
I
S
-
E
R
I
E
E
V
A
V
Y
S
Y
P
Q
L
V
E
Q
H
----
E
----------
I
----
T
-
G
R
I
F
I
S
L
A
V
K
F
S
K
A
R
L
I
D
N
I
I
I
G
----
114
HHSearch
93.34
43%
-107
- C5 -
3MXT
8
PANC_CAMJE
A:
[4-283]
M
Q
V
I
T
S
V
K
E
A
K
Q
I
V
K
D
W
K
S
H
Q
L
S
I
G
Y
V
P
T
M
G
F
L
H
D
G
H
L
S
L
V
K
H
A
K
T
---
Q
D
K
V
I
V
S
I
F
V
N
P
M
Q
F
G
P
N
E
D
F
S
S
Y
P
R
D
L
E
R
D
I
K
M
C
Q
D
N
G
V
D
M
V
F
I
P
D
A
T
Q
M
Y
L
----
K
N
F
S
--
T
Y
--
V
D
M
N
--
T
I
T
D
-
K
L
-
C
G
A
K
R
P
G
H
F
R
G
V
C
T
V
L
T
K
F
F
N
I
L
N
P
D
I
V
Y
M
G
Q
K
D
A
Q
Q
C
V
V
V
R
H
M
V
D
D
L
N
F
D
L
K
I
Q
I
C
P
I
I
R
E
E
D
G
L
A
K
S
S
R
N
V
Y
L
S
K
E
E
R
K
A
S
L
-------
A
I
S
Q
S
I
F
-
L
A
E
K
L
V
R
E
-
G
E
K
N
T
S
K
I
I
Q
A
M
K
D
I
L
E
K
E
K
-
L
I
-
K
I
D
Y
I
E
L
V
D
F
N
T
M
E
N
I
E
----
N
----------
I
----
T
-
D
N
V
L
G
A
V
A
A
F
V
G
K
T
R
L
I
D
N
F
L
V
Q
G
---
7
PsiBlast_PDB
92.79
43%
-102
- C5 -
3UY4
3
PANC_CAMJE
A:
[6-281]
--
V
I
T
S
V
K
E
A
K
Q
I
V
K
D
W
K
S
H
Q
L
S
I
G
Y
V
P
T
M
G
F
L
H
D
G
H
L
S
L
V
K
H
A
-
K
-
T
-
Q
D
K
V
I
V
S
I
F
V
N
P
M
Q
F
G
P
N
E
D
F
S
S
Y
P
R
D
L
E
R
D
I
K
M
C
Q
D
N
G
V
D
M
V
F
I
P
D
A
T
Q
M
Y
L
----
K
N
F
S
--
T
Y
--
V
D
M
N
--
T
I
T
D
-
K
L
-
C
G
A
K
R
P
G
H
F
R
G
V
C
T
V
L
T
K
F
F
N
I
L
N
P
D
I
V
Y
M
G
Q
K
D
A
Q
Q
C
V
V
V
R
H
M
V
D
D
L
N
F
D
L
K
I
Q
I
C
P
I
I
R
E
E
D
G
L
A
K
S
S
R
N
V
Y
L
S
K
E
E
R
K
A
S
L
-------
A
I
S
Q
S
I
F
-
L
A
E
K
L
V
R
E
-
G
E
K
N
T
S
K
I
I
Q
A
M
K
D
-
I
L
-
E
K
E
K
L
I
K
I
D
Y
I
E
L
V
D
F
N
T
M
E
N
I
E
----
N
----------
I
----
T
-
D
N
V
L
G
A
V
A
A
F
V
G
K
T
R
L
I
D
N
F
L
V
-----
1
PsiBlast_PDB
92.11
49%
-107
- C5 -
3AG5
-
PANC_STAA8
A:
[4-281]
--
L
I
T
T
V
K
E
M
Q
H
I
V
K
A
A
K
R
S
G
T
T
I
G
F
I
P
T
M
G
A
L
H
D
G
H
L
T
M
V
R
E
S
V
S
-
T
-
N
D
I
T
I
V
S
V
F
V
N
P
L
Q
F
G
-----
D
A
Y
P
R
Q
I
D
K
D
L
E
L
V
S
E
V
G
A
D
I
V
F
H
P
A
V
E
D
M
Y
P
----
G
E
L
G
--
I
D
--
V
K
V
G
--
P
L
A
D
-
V
L
-
E
G
A
K
R
P
G
H
F
D
G
V
V
T
V
V
N
K
L
F
N
I
V
M
P
D
Y
A
Y
F
G
K
K
D
A
Q
Q
L
A
I
V
E
Q
M
V
K
D
F
N
H
A
V
E
I
I
G
I
D
I
V
R
E
A
D
G
L
A
K
S
S
R
N
V
Y
L
T
E
Q
E
R
Q
E
A
V
-------
H
L
S
K
S
L
L
-
L
A
Q
A
L
Y
Q
D
-
G
E
R
Q
S
K
V
I
I
D
R
V
T
E
Y
L
E
-
S
H
I
S
-
E
R
I
E
E
V
A
V
Y
S
Y
P
Q
L
V
E
Q
H
----
E
----------
I
----
T
-
G
R
I
F
I
S
L
A
V
K
F
S
K
A
R
L
I
D
N
I
I
I
G
----
6
PsiBlast_PDB
91.64
43%
-102
- C5 -
3MXT
8
PANC_CAMJE
A:
[6-281]
--
V
I
T
S
V
K
E
A
K
Q
I
V
K
D
W
K
S
H
Q
L
S
I
G
Y
V
P
T
M
G
F
L
H
D
G
H
L
S
L
V
K
H
A
-
K
-
T
-
Q
D
K
V
I
V
S
I
F
V
N
P
M
Q
F
G
P
N
E
D
F
S
S
Y
P
R
D
L
E
R
D
I
K
M
C
Q
D
N
G
V
D
M
V
F
I
P
D
A
T
Q
M
Y
L
----
K
N
F
S
--
T
Y
--
V
D
M
N
--
T
I
T
D
-
K
L
-
C
G
A
K
R
P
G
H
F
R
G
V
C
T
V
L
T
K
F
F
N
I
L
N
P
D
I
V
Y
M
G
Q
K
D
A
Q
Q
C
V
V
V
R
H
M
V
D
D
L
N
F
D
L
K
I
Q
I
C
P
I
I
R
E
E
D
G
L
A
K
S
S
R
N
V
Y
L
S
K
E
E
R
K
A
S
L
-------
A
I
S
Q
S
I
F
-
L
A
E
K
L
V
R
E
-
G
E
K
N
T
S
K
I
I
Q
A
M
K
D
-
I
L
-
E
K
E
K
L
I
K
I
D
Y
I
E
L
V
D
F
N
T
M
E
N
I
E
----
N
----------
I
----
T
-
D
N
V
L
G
A
V
A
A
F
V
G
K
T
R
L
I
D
N
F
L
V
-----
12
PsiBlast_PDB
91.38
39%
-104
- C5 -
1IHO
2
PANC_ECOLI
A:
[1-282]
M
L
I
I
E
T
L
P
L
L
R
Q
Q
I
R
R
L
R
M
E
G
K
R
V
A
L
V
P
T
M
G
N
L
H
D
G
H
M
K
L
V
D
E
A
K
A
-
R
-
A
D
V
V
V
V
S
I
F
V
N
P
M
Q
F
D
R
P
E
D
L
A
R
Y
P
R
T
L
Q
E
D
C
E
K
L
N
K
R
K
V
D
L
V
F
A
P
S
V
K
E
I
Y
P
NG--
T
E
T
H
--
T
Y
--
V
D
V
P
--
G
L
S
T
-
M
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
V
Q
P
D
I
A
C
F
G
E
K
D
F
Q
Q
L
A
L
I
R
K
M
V
A
D
M
G
F
D
I
E
I
V
G
V
P
I
M
R
A
K
D
G
L
A
L
S
S
R
N
G
Y
L
T
A
E
Q
R
K
I
A
P
-------
G
L
Y
K
V
L
S
-
S
I
A
D
K
L
Q
A
-
G
E
R
D
L
D
E
I
I
T
I
A
G
Q
E
L
N
-
E
K
G
F
R
A
--
D
D
I
Q
I
R
D
A
D
T
L
L
E
V
S
----
E
----------
T
----
S
-
K
R
A
V
I
L
V
A
A
W
L
G
D
A
R
L
I
D
N
K
M
V
E
L
---
112
HHSearch
91.25
41%
-104
- C5 -
3INN
3
PANC_BRUME
A:
[22-303]
M
Q
I
I
H
T
I
E
E
L
R
Q
A
L
A
P
A
R
Q
Q
G
K
K
I
G
F
V
P
T
M
G
Y
L
H
K
G
H
L
E
L
V
R
R
A
R
V
-
E
-
N
D
V
T
L
V
S
I
F
V
N
P
L
Q
F
G
A
N
E
D
L
G
R
Y
P
R
D
L
E
R
D
A
G
L
L
H
D
A
Q
V
D
Y
L
F
A
P
T
V
S
D
M
Y
P
----
R
P
M
Q
--
T
V
--
V
D
V
P
--
P
L
G
N
-
Q
I
-
E
G
E
A
R
P
G
H
F
A
G
V
A
T
V
V
S
K
L
F
N
I
V
G
P
D
A
A
Y
F
G
E
K
D
F
Q
Q
L
V
I
I
R
R
M
V
D
D
M
A
I
P
V
R
I
V
G
V
E
T
V
R
E
D
D
G
L
A
C
S
S
R
N
V
Y
L
T
P
E
Q
R
R
A
A
I
-------
I
V
P
Q
A
L
D
-
E
A
D
R
L
Y
R
S
-
G
M
D
D
P
D
A
L
E
A
A
I
R
T
F
I
G
R
Q
P
-
L
A
-
V
P
E
V
I
A
I
R
D
P
E
T
L
E
R
L
P
----
A
----------
L
----
Q
G
R
P
I
L
V
A
L
F
V
R
V
G
A
T
R
L
L
D
N
R
V
I
G
H
---
32
PsiBlast_CBE
91.18
39%
-105
- C5 -
1IHO
1
PANC_ECOLI
B:
[1-282]
M
L
I
I
E
T
L
P
L
L
R
Q
Q
I
R
R
L
R
M
E
G
K
R
V
A
L
V
P
T
M
G
N
L
H
D
G
H
M
K
L
V
D
E
A
K
A
-
R
-
A
D
V
V
V
V
S
I
F
V
N
P
M
Q
F
D
R
P
E
D
L
A
R
Y
P
R
T
L
Q
E
D
C
E
K
L
N
K
R
K
V
D
L
V
F
A
P
S
V
K
E
I
Y
P
NG--
T
E
T
H
--
T
Y
--
V
D
V
P
--
G
L
S
T
-
M
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
V
Q
P
D
I
A
C
F
G
E
K
D
F
Q
Q
L
A
L
I
R
K
M
V
A
D
M
G
F
D
I
E
I
V
G
V
P
I
M
R
A
K
D
G
L
A
L
S
S
R
N
G
Y
L
T
A
E
Q
R
K
I
A
P
-------
G
L
Y
K
V
L
S
-
S
I
A
D
K
L
Q
A
-
G
E
R
D
L
D
E
I
I
T
I
A
G
Q
E
L
N
-
E
K
G
F
R
A
--
D
D
I
Q
I
R
D
A
D
T
L
L
E
V
S
----
E
----------
T
----
S
-
K
R
A
V
I
L
V
A
A
W
L
G
D
A
R
L
I
D
N
K
M
V
E
L
---
101
Fugue
90.81
38%
-110
- C5 -
1IHO
2
PANC_ECOLI
A:
[1-282]
M
L
I
I
E
T
L
P
L
L
R
Q
Q
I
R
R
L
R
M
E
G
K
R
V
A
L
V
P
T
M
G
N
L
H
D
G
H
M
K
L
V
D
E
A
K
A
-
R
-
A
D
V
V
V
V
S
I
F
V
N
P
M
Q
F
D
R
P
E
D
L
A
R
Y
P
R
T
L
Q
E
D
C
E
K
L
N
K
R
K
V
D
L
V
F
A
P
S
V
K
E
I
Y
P
----
N
G
T
E
--
T
H
T
Y
V
D
V
P
--
G
L
S
T
-
M
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
V
Q
P
D
I
A
C
F
G
E
K
D
F
Q
Q
L
A
L
I
R
K
M
V
A
D
M
G
F
D
I
E
I
V
G
V
P
I
M
R
A
K
D
G
L
A
L
S
S
R
N
G
Y
L
T
A
E
Q
R
K
I
A
P
-------
G
L
Y
K
V
L
S
-
S
I
A
D
K
L
Q
A
-
G
E
R
D
L
D
E
I
I
T
I
A
G
Q
E
L
N
-
E
K
G
F
--
R
A
D
D
I
Q
I
R
D
A
D
T
L
L
E
V
S
----
E
----------
T
----
S
-
K
R
A
V
I
L
V
A
A
W
L
G
D
A
R
L
I
D
N
K
M
V
E
L
---
25
PsiBlast_CBE
89.89
40%
-94
- C5 -
3INN
4
PANC_BRUME
C:
[22-302]
M
Q
I
I
H
T
I
E
E
L
R
Q
A
L
A
P
A
R
Q
Q
G
K
K
I
G
F
V
P
T
M
G
Y
L
H
K
G
H
L
E
L
V
R
R
A
R
V
-
E
-
N
D
V
T
L
V
S
I
F
V
N
P
L
Q
F
G
A
N
E
D
L
G
R
Y
P
R
D
L
E
R
D
A
G
L
L
H
D
A
Q
V
D
Y
L
F
A
P
T
V
S
D
M
Y
P
----
R
P
M
Q
--
T
V
--
V
D
V
P
--
P
L
G
N
-
Q
I
-
E
G
E
A
R
P
G
H
F
A
G
V
A
T
V
V
S
K
L
F
N
I
V
G
P
D
A
A
Y
F
G
E
K
D
F
Q
Q
L
V
I
I
R
R
M
V
D
D
M
A
I
P
V
R
I
V
G
V
E
T
V
R
E
D
D
G
L
A
C
S
S
R
N
V
Y
L
T
P
E
Q
R
R
A
A
I
-------
I
V
P
Q
A
L
D
-
E
A
D
R
L
Y
R
S
-
G
M
D
D
P
D
A
L
E
A
A
I
R
T
F
I
G
-
R
Q
P
----------
L
A
V
P
E
V
I
A
I
R
----
D
PE
T
L
E
R
L
P
A
L
Q
----
G
-
R
P
I
L
V
A
L
F
V
R
V
G
A
T
R
L
L
D
N
R
V
I
G
----
9
PsiBlast_PDB
89.37
40%
-95
- C5 -
3INN
3
PANC_BRUME
A:
[22-302]
M
Q
I
I
H
T
I
E
E
L
R
Q
A
L
A
P
A
R
Q
Q
G
K
K
I
G
F
V
P
T
M
G
Y
L
H
K
G
H
L
E
L
V
R
R
A
R
V
-
E
-
N
D
V
T
L
V
S
I
F
V
N
P
L
Q
F
G
A
N
E
D
L
G
R
Y
P
R
D
L
E
R
D
A
G
L
L
H
D
A
Q
V
D
Y
L
F
A
P
T
V
S
D
M
Y
P
----
R
P
M
Q
--
T
V
--
V
D
V
P
--
P
L
G
N
-
Q
I
-
E
G
E
A
R
P
G
H
F
A
G
V
A
T
V
V
S
K
L
F
N
I
V
G
P
D
A
A
Y
F
G
E
K
D
F
Q
Q
L
V
I
I
R
R
M
V
D
D
M
A
I
P
V
R
I
V
G
V
E
T
V
R
E
D
D
G
L
A
C
S
S
R
N
V
Y
L
T
P
E
Q
R
R
A
A
I
-------
I
V
P
Q
A
L
D
-
E
A
D
R
L
Y
R
S
-
G
M
D
D
P
D
A
L
E
A
A
I
R
T
F
I
G
-
R
Q
P
----------
L
A
V
P
E
V
I
A
I
R
----
D
PETLERLPAL
Q
----
G
-
R
P
I
L
V
A
L
F
V
R
V
G
A
T
R
L
L
D
N
R
V
I
G
----
116
HHSearch
89.14
39%
-108
- C5 -
3UK2
7
PANC_BURTA
A:
[5-283]
M
K
V
I
S
S
I
Q
E
L
R
D
Q
L
----
R
G
Q
N
R
T
A
F
V
P
T
M
G
N
L
H
E
G
H
L
S
L
M
R
L
A
R
Q
-
H
-
G
D
P
V
V
A
S
I
F
V
N
R
L
Q
F
G
P
N
E
D
F
D
K
Y
P
R
T
L
Q
E
D
I
E
K
L
Q
K
E
N
V
Y
V
L
F
A
P
T
E
R
D
M
Y
P
----
E
P
Q
E
--
Y
R
--
V
Q
P
P
H
-
D
L
G
D
-
I
L
-
E
G
E
F
R
P
G
F
F
T
G
V
C
T
V
V
T
K
L
M
A
C
V
Q
P
R
V
A
V
F
G
K
K
D
Y
Q
Q
L
M
I
V
R
R
M
C
Q
Q
L
A
L
P
V
E
I
V
A
A
E
T
V
R
D
A
D
G
L
A
L
S
S
R
N
R
Y
L
S
E
A
E
R
A
E
A
P
-------
E
L
A
K
T
L
A
-
R
V
R
D
A
V
L
D
-
G
E
R
D
L
A
A
I
E
R
R
A
V
A
H
L
S
-
A
R
-
G
W
-
Q
P
D
Y
V
S
I
R
R
R
E
N
L
V
A
P
S
----
A
----------
A
Q
I
E
A
G
-
D
P
L
V
V
L
T
A
A
K
L
G
A
T
R
L
I
D
N
L
E
I
-----
14
PsiBlast_PDB
88.52
38%
-103
- C5 -
3UK2
7
PANC_BURTA
A:
[5-280]
M
K
V
I
S
S
I
Q
E
L
R
D
Q
L
R
G
Q
---
N
R
T
-
A
F
V
P
T
M
G
N
L
H
E
G
H
L
S
L
M
R
L
A
R
Q
-
H
-
G
D
P
V
V
A
S
I
F
V
N
R
L
Q
F
G
P
N
E
D
F
D
K
Y
P
R
T
L
Q
E
D
I
E
K
L
Q
K
E
N
V
Y
V
L
F
A
P
T
E
R
D
M
Y
P
----
E
P
Q
E
--
Y
R
--
V
Q
P
P
--
H
D
L
G
D
I
L
-
E
G
E
F
R
P
G
F
F
T
G
V
C
T
V
V
T
K
L
M
A
C
V
Q
P
R
V
A
V
F
G
K
K
D
Y
Q
Q
L
M
I
V
R
R
M
C
Q
Q
L
A
L
P
V
E
I
V
A
A
E
T
V
R
D
A
D
G
L
A
L
S
S
R
N
R
Y
L
S
E
A
E
R
A
E
A
P
-------
E
L
A
K
T
L
A
-
R
V
R
D
A
V
L
D
-
G
E
R
D
L
A
A
I
E
R
R
A
V
A
H
L
S
-
A
R
G
W
Q
P
--
D
Y
V
S
I
R
R
R
E
N
L
V
A
P
S
A
A
Q
I
E
----------
A
----
G
-
D
P
L
V
V
L
T
A
A
K
L
G
A
T
R
L
I
D
N
--------
36
PsiBlast_CBE
87.94
38%
-103
- C5 -
3UK2
4
PANC_BURTA
B:
[5-280]
M
K
V
I
S
S
I
Q
E
L
R
D
Q
L
R
G
Q
---
N
R
T
-
A
F
V
P
T
M
G
N
L
H
E
G
H
L
S
L
M
R
L
A
R
Q
-
H
-
G
D
P
V
V
A
S
I
F
V
N
R
L
Q
F
G
P
N
E
D
F
D
K
Y
P
R
T
L
Q
E
D
I
E
K
L
Q
K
E
N
V
Y
V
L
F
A
P
T
E
R
D
M
Y
P
----
E
P
Q
E
--
Y
R
--
V
Q
P
P
--
H
D
L
G
D
I
L
-
E
G
E
F
R
P
G
F
F
T
G
V
C
T
V
V
T
K
L
M
A
C
V
Q
P
R
V
A
V
F
G
K
K
D
Y
Q
Q
L
M
I
V
R
R
M
C
Q
Q
L
A
L
P
V
E
I
V
A
A
E
T
V
R
D
A
D
G
L
A
L
S
S
R
N
R
Y
L
S
E
A
E
R
A
E
A
P
-------
E
L
A
K
T
L
A
-
R
V
R
D
A
V
L
D
-
G
E
R
D
L
A
A
I
E
R
R
A
V
A
H
L
S
-
A
R
G
W
Q
P
--
D
Y
V
S
I
R
R
R
E
N
L
V
A
P
S
AAQI
E
----------
A
----
G
-
D
P
L
V
V
L
T
A
A
K
L
G
A
T
R
L
I
D
N
--------
119
HHSearch
87.47
45%
-100
- C5 -
1V8F
11
PANC_THET8
A:
[1-275]
M
R
T
V
S
T
V
A
E
L
R
A
A
L
-----
P
R
E
G
V
G
F
V
P
T
M
G
Y
L
H
R
G
H
L
A
L
V
E
R
A
R
R
-
E
-
N
P
F
V
V
V
S
V
F
V
N
P
L
Q
F
G
P
G
E
D
Y
H
R
Y
P
R
D
L
E
R
D
R
A
L
L
Q
E
A
G
V
D
L
L
F
A
P
G
V
E
E
M
Y
P
----
E
G
F
A
--
T
R
--
V
Q
V
E
G
-
P
L
T
A
-
L
W
-
E
G
A
V
R
P
G
H
F
Q
G
V
A
T
V
V
A
R
L
F
L
L
V
Q
P
Q
R
A
Y
F
G
E
K
D
Y
Q
Q
L
L
V
V
R
R
M
V
R
D
L
G
F
P
V
E
V
V
G
V
P
T
V
R
E
E
D
G
L
A
L
S
S
R
N
V
Y
L
S
P
E
T
R
K
K
A
P
-------
V
L
Y
R
A
L
L
-
A
M
R
E
V
A
G
Q
-
G
G
S
V
A
E
A
L
R
A
G
-
E
E
A
L
R
A
V
P
-
E
F
-
R
K
D
Y
L
A
I
V
H
P
E
T
L
L
P
L
S
----
D
----------
W
----
V
-
A
G
A
R
G
I
V
A
G
R
F
P
E
A
R
L
I
D
N
L
E
V
Y
----
34
PsiBlast_CBE
86.68
38%
-107
- C5 -
3MUE
8
PANC_SALTY
C:
[4-285]
M
L
I
I
E
T
L
P
L
L
R
Q
H
I
R
R
L
R
Q
E
G
K
R
V
A
L
V
P
T
M
G
N
L
H
D
G
H
M
K
L
V
D
E
A
K
A
-
R
-
A
D
V
V
I
V
S
I
F
V
N
P
M
Q
F
D
R
P
D
D
L
V
R
Y
P
R
T
L
Q
E
D
C
E
K
L
N
K
R
K
V
D
Y
V
F
A
P
A
V
E
E
I
Y
P
----
H
G
L
E
--
G
Q
--
T
Y
V
D
VP
G
L
S
T
-
M
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
I
Q
P
D
I
A
C
F
G
E
K
D
F
Q
Q
L
A
L
I
R
K
M
V
A
D
M
S
Y
D
I
E
I
V
G
V
P
I
I
R
A
K
D
G
L
A
L
S
S
R
N
A
Y
L
T
A
E
Q
R
K
I
A
P
-------
G
L
Y
N
V
M
N
S
I
A
E
K
L
I
-
A
-
G
N
R
E
L
Q
E
I
I
A
I
A
E
Q
E
L
N
-
E
K
G
F
R
A
--
D
D
I
Q
I
R
D
A
D
T
L
L
E
L
T
----
E
----------
T
----
S
-
K
R
A
V
I
L
A
A
A
W
L
G
Q
A
R
L
I
D
N
Q
S
V
T
L
---
118
HHSearch
86.66
40%
-102
- C5 -
3Q12
2
PANC_YERPE
A:
[4-286]
M
L
I
I
E
T
L
P
L
L
R
Q
Q
I
R
R
W
R
Q
E
G
K
R
I
A
L
V
P
T
M
G
N
L
H
E
G
H
M
T
L
V
D
E
A
K
T
-
R
-
A
D
V
V
V
V
T
I
F
V
N
P
L
Q
F
E
R
P
D
D
L
A
H
Y
P
R
T
L
Q
E
D
C
E
K
L
T
R
H
G
A
D
L
V
F
A
P
A
A
A
D
I
Y
P
----
A
G
L
E
K
Q
T
Y
--
V
D
V
P
--
A
L
S
T
-
I
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
I
Q
P
D
V
A
C
F
G
E
K
D
Y
Q
Q
L
A
L
I
R
K
M
V
A
D
M
G
Y
D
I
N
I
V
G
V
P
T
V
R
A
K
D
G
L
A
L
S
S
R
N
G
Y
L
T
E
E
E
R
Q
I
A
P
-------
Q
L
S
K
I
M
W
-
A
L
A
E
K
M
A
L
-
G
E
R
Q
I
D
A
L
L
E
E
A
A
A
Q
L
L
-
R
V
-
G
F
-
T
P
D
E
L
F
I
R
D
A
E
T
L
Q
P
L
T
----
V
----------
D
----
S
-
Q
Q
A
V
I
L
M
A
A
W
L
G
K
A
R
L
I
D
N
Q
L
V
D
L
R
--
13
PsiBlast_PDB
86.46
38%
-107
- C5 -
3MUE
11
PANC_SALTY
A:
[4-285]
M
L
I
I
E
T
L
P
L
L
R
Q
H
I
R
R
L
R
Q
E
G
K
R
V
A
L
V
P
T
M
G
N
L
H
D
G
H
M
K
L
V
D
E
A
K
A
-
R
-
A
D
V
V
I
V
S
I
F
V
N
P
M
Q
F
D
R
P
D
D
L
V
R
Y
P
R
T
L
Q
E
D
C
E
K
L
N
K
R
K
V
D
Y
V
F
A
P
A
V
E
E
I
Y
P
----
H
G
L
E
--
G
Q
--
T
Y
V
D
V
P
G
L
S
T
-
M
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
I
Q
P
D
I
A
C
F
G
E
K
D
F
Q
Q
L
A
L
I
R
K
M
V
A
D
M
S
Y
D
I
E
I
V
G
V
P
I
I
R
A
K
D
G
L
A
L
S
S
R
N
A
Y
L
T
A
E
Q
R
K
I
A
P
-------
G
L
Y
N
V
M
N
S
I
A
E
K
L
I
-
A
-
G
N
R
E
L
Q
E
I
I
A
I
A
E
Q
E
L
N
-
E
K
G
F
R
A
--
D
D
I
Q
I
R
D
A
D
T
L
L
E
L
T
----
E
----------
T
----
S
-
K
R
A
V
I
L
A
A
A
W
L
G
Q
A
R
L
I
D
N
Q
S
V
T
L
---
8
PsiBlast_PDB
86.42
46%
-91
- C5 -
1UFV
6
PANC_THET8
A:
[10-271]
--------------
L
R
A
A
L
P
R
E
G
V
G
F
V
P
T
M
G
Y
L
H
R
G
H
L
A
L
V
E
R
A
R
R
-
E
-
N
P
F
V
V
A
S
V
F
V
N
P
L
Q
F
G
P
G
E
D
Y
H
R
Y
P
R
D
L
E
R
D
R
A
L
L
Q
E
A
G
V
D
L
L
F
A
P
G
V
E
E
M
Y
P
----
E
G
F
A
--
T
R
--
V
Q
V
E
--
G
P
L
T
-
A
L
W
E
G
A
V
R
P
G
H
F
Q
G
V
A
T
V
V
A
R
L
F
L
L
V
Q
P
Q
R
A
Y
F
G
E
K
D
Y
Q
Q
L
L
V
V
R
R
M
V
R
D
L
G
F
P
V
E
V
V
G
V
P
T
V
R
E
E
D
G
L
A
L
S
S
R
N
V
Y
L
S
P
E
T
R
K
K
A
P
-------
V
L
Y
R
A
L
L
-
A
M
R
E
V
--
A
-
G
Q
G
G
S
V
A
E
A
L
R
A
G
E
E
A
L
-
R
A
V
P
E
F
R
K
D
Y
L
A
I
V
H
P
E
T
L
L
P
L
S
----
D
----------
W
----
V
-
A
G
A
R
G
I
V
A
G
R
F
P
E
A
R
L
I
D
N
--------
24
PsiBlast_CBE
86.36
40%
-99
- C5 -
3INN
1
PANC_BRUME
D:
[22-302]
M
Q
I
I
H
T
I
E
E
L
R
Q
A
L
A
P
A
R
Q
Q
G
K
K
I
G
F
V
P
T
M
G
Y
L
H
K
G
H
L
E
L
V
R
R
A
R
V
-
E
-
N
D
V
T
L
V
S
I
F
V
N
P
L
Q
F
G
A
N
--------
D
L
E
R
D
A
G
L
L
H
D
A
Q
V
D
Y
L
F
A
P
T
V
S
D
M
Y
P
----
R
P
M
Q
--
T
V
--
V
D
V
P
--
P
L
G
N
-
Q
I
-
E
G
E
--
P
G
H
F
A
G
V
A
T
V
V
S
K
L
F
N
I
V
G
P
D
A
A
Y
F
G
E
K
D
F
Q
Q
L
V
I
I
R
R
M
V
D
D
M
A
I
P
V
R
I
V
G
V
E
T
V
R
E
D
D
G
L
A
C
S
S
R
N
V
Y
L
T
P
E
Q
R
R
A
A
I
-------
I
V
P
Q
A
L
D
-
E
A
D
R
L
Y
R
S
-
G
M
D
D
P
D
A
L
E
A
A
I
R
T
F
I
G
-
R
Q
P
----------
L
A
V
P
E
V
I
A
I
R
----
D
PETLERLPAL
Q
----
G
-
R
P
I
L
V
A
L
F
V
R
V
G
A
T
R
L
L
D
N
R
V
I
G
----
5
PsiBlast_PDB
85.07
46%
-91
- C5 -
1V8F
11
PANC_THET8
A:
[10-271]
--------------
L
R
A
A
L
P
R
E
G
V
G
F
V
P
T
M
G
Y
L
H
R
G
H
L
A
L
V
E
R
A
R
R
-
E
-
N
P
F
V
V
V
S
V
F
V
N
P
L
Q
F
G
P
G
E
D
Y
H
R
Y
P
R
D
L
E
R
D
R
A
L
L
Q
E
A
G
V
D
L
L
F
A
P
G
V
E
E
M
Y
P
----
E
G
F
A
--
T
R
--
V
Q
V
E
--
G
P
L
T
-
A
L
W
E
G
A
V
R
P
G
H
F
Q
G
V
A
T
V
V
A
R
L
F
L
L
V
Q
P
Q
R
A
Y
F
G
E
K
D
Y
Q
Q
L
L
V
V
R
R
M
V
R
D
L
G
F
P
V
E
V
V
G
V
P
T
V
R
E
E
D
G
L
A
L
S
S
R
N
V
Y
L
S
P
E
T
R
K
K
A
P
-------
V
L
Y
R
A
L
L
-
A
M
R
E
V
--
A
-
G
Q
G
G
S
V
A
E
A
L
R
A
G
E
E
A
L
-
R
A
V
P
E
F
R
K
D
Y
L
A
I
V
H
P
E
T
L
L
P
L
S
----
D
----------
W
----
V
-
A
G
A
R
G
I
V
A
G
R
F
P
E
A
R
L
I
D
N
--------
26
PsiBlast_CBE
84.91
39%
-103
- C5 -
3Q12
1
PANC_YERPE
D:
[4-285]
M
L
I
I
E
T
L
P
L
L
R
Q
Q
I
R
R
W
R
Q
E
G
K
R
I
A
L
V
P
T
M
G
N
L
H
E
G
H
M
T
L
V
D
E
A
K
T
-
R
-
A
D
V
V
V
V
T
I
F
V
N
P
L
Q
F
E
R
P
D
D
L
A
H
Y
P
R
T
L
Q
E
D
C
E
K
L
T
R
H
G
A
D
L
V
F
A
P
A
A
A
D
I
Y
P
----
A
G
L
E
--
K
Q
--
T
Y
V
D
VP
A
L
S
T
-
I
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
I
Q
P
D
V
A
C
F
G
E
K
D
Y
Q
Q
L
A
L
I
R
K
M
V
A
D
M
G
Y
D
I
N
I
V
G
V
P
T
V
R
A
K
D
G
L
A
L
S
S
R
N
G
Y
L
T
E
E
E
R
Q
I
A
P
QLSKIMW
A
L
A
E
K
M
A
-
L
G
E
R
Q
I
D
A
L
L
E
E
A
A
A
Q
L
L
R
V
G
F
-------
T
P
D
E
L
F
----
I
R
D
A
E
T
L
Q
P
L
T
----
V
----------
D
----
S
-
Q
Q
A
V
I
L
M
A
A
W
L
G
K
A
R
L
I
D
N
Q
L
V
D
L
---
23
PsiBlast_CBE
84.33
46%
-91
- C5 -
1V8F
5
PANC_THET8
B:
[10-271]
--------------
L
R
A
A
L
P
R
E
G
V
G
F
V
P
T
M
G
Y
L
H
R
G
H
L
A
L
V
E
R
A
R
R
-
E
-
N
P
F
V
V
V
S
V
F
V
N
P
L
Q
F
G
P
G
E
D
Y
H
R
Y
P
R
D
L
E
R
D
R
A
L
L
Q
E
A
G
V
D
L
L
F
A
P
G
V
E
E
M
Y
P
----
E
G
F
A
--
T
R
--
V
Q
V
E
--
G
P
L
T
-
A
L
W
E
G
A
V
R
P
G
H
F
Q
G
V
A
T
V
V
A
R
L
F
L
L
V
Q
P
Q
R
A
Y
F
G
E
K
D
Y
Q
Q
L
L
V
V
R
R
M
V
R
D
L
G
F
P
V
E
V
V
G
V
P
T
V
R
E
E
D
G
L
A
L
S
S
R
N
V
Y
L
S
P
E
T
R
K
K
A
P
-------
V
L
Y
R
A
L
L
-
A
M
R
E
V
--
A
-
G
Q
G
G
S
V
A
E
A
L
R
A
G
E
E
A
L
-
R
A
V
P
E
F
R
K
D
Y
L
A
I
V
H
P
E
T
L
L
P
L
S
----
D
----------
W
----
V
-
A
G
A
R
G
I
V
A
G
R
F
P
E
A
R
L
I
D
N
--------
35
PsiBlast_CBE
83.97
38%
-101
- C5 -
3MUE
9
PANC_SALTY
B:
[4-285]
M
L
I
I
E
T
L
P
L
L
R
Q
H
I
R
R
L
R
Q
E
G
K
R
V
A
L
V
P
T
M
G
N
L
H
D
G
H
M
K
L
V
D
E
A
K
A
-
R
-
A
D
V
V
I
V
S
I
F
V
N
P
M
Q
F
D
R
P
D
D
L
V
R
Y
P
R
T
L
Q
E
D
C
E
K
L
N
K
R
K
V
D
Y
V
F
A
P
A
V
E
E
I
Y
P
----
H
G
L
E
--
G
Q
--
T
Y
V
D
V
P
G
L
S
T
-
M
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
I
Q
P
D
I
A
C
F
G
E
K
D
F
Q
Q
L
A
L
I
R
K
M
V
A
D
M
S
Y
D
I
E
I
V
G
V
P
I
I
R
A
K
D
G
L
A
L
S
S
R
N
A
Y
L
T
A
E
Q
R
K
I
A
P
-------
G
L
Y
N
V
M
N
S
I
A
E
K
L
I
-
A
-
G
N
R
E
L
Q
E
I
I
A
I
A
E
Q
E
L
N
-
E
K
G
F
R
A
--
D
D
I
Q
I
R
D
A
D
T
L
L
E
L
T
----
E
----------
T
----
S
-
K
R
A
V
I
L
A
A
A
W
L
G
Q
A
R
L
I
D
N
Q
S
V
T
L
---
27
PsiBlast_CBE
83.41
39%
-91
- C5 -
3Q12
2
PANC_YERPE
C:
[4-286]
M
L
I
I
E
T
L
P
L
L
R
Q
Q
I
R
R
W
R
Q
E
G
K
R
I
A
L
V
P
T
M
G
N
L
H
E
G
H
M
T
L
V
D
E
A
K
T
-
R
-
A
D
V
V
V
V
T
I
F
V
N
P
L
Q
F
E
R
P
D
D
L
A
H
Y
P
R
T
L
Q
E
D
C
E
K
L
T
R
H
G
A
D
L
V
F
A
P
A
A
A
D
I
Y
P
----
A
G
L
E
--
K
Q
--
T
Y
V
D
VP
A
L
S
T
-
I
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
I
Q
P
D
V
A
C
F
G
E
K
D
Y
Q
Q
L
A
L
I
R
K
M
V
A
D
M
G
Y
D
I
N
I
V
G
V
P
T
V
R
A
K
D
G
L
A
L
S
S
R
N
G
Y
L
T
E
E
E
R
Q
I
A
P
QLSKIMW
A
L
A
E
K
M
A
-
L
G
E
R
Q
I
D
A
L
L
E
E
A
A
A
Q
L
L
R
V
G
F
-------
T
P
D
E
L
F
----
I
R
D
A
E
T
L
Q
P
L
T
----
V
----------
D
----
S
-
Q
Q
A
V
I
L
M
A
A
W
L
G
K
A
R
L
I
D
N
Q
L
V
D
L
R
--
30
PsiBlast_CBE
83.17
39%
-98
- C5 -
3Q10
2
PANC_YERPE
C:
[4-285]
M
L
I
I
E
T
L
P
L
L
R
Q
Q
I
R
R
W
R
Q
E
G
K
R
I
A
L
V
P
T
M
G
N
L
H
E
G
H
M
T
L
V
D
E
A
K
T
-
R
-
A
D
V
V
V
V
T
I
F
V
N
P
L
Q
F
E
R
P
D
D
L
A
H
Y
P
R
T
L
Q
E
D
C
E
K
L
T
R
H
G
A
D
L
V
F
A
P
A
A
A
D
I
Y
P
----
A
G
L
E
--
K
Q
--
T
Y
V
D
VP
A
L
S
T
-
I
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
I
Q
P
D
V
A
C
F
G
E
K
D
Y
Q
Q
L
A
L
I
R
K
M
V
A
D
M
G
Y
D
I
N
I
V
G
V
P
T
V
R
A
K
D
G
L
A
L
S
S
R
N
G
Y
L
T
E
E
E
R
Q
I
A
P
QLSKIMW
A
L
A
E
K
M
A
-
L
G
E
R
Q
I
D
A
L
L
E
E
A
A
A
Q
L
L
R
V
G
F
-------
T
P
D
E
L
F
----
I
R
D
A
E
T
L
Q
P
L
T
----
V
----------
D
----
S
-
Q
Q
A
V
I
L
M
A
A
W
L
G
K
A
R
L
I
D
N
Q
L
V
D
L
---
28
PsiBlast_CBE
82.44
39%
-96
- C5 -
3Q12
1
PANC_YERPE
B:
[4-285]
M
L
I
I
E
T
L
P
L
L
R
Q
Q
I
R
R
W
R
Q
E
G
K
R
I
A
L
V
P
T
M
G
N
L
H
E
G
H
M
T
L
V
D
E
A
K
T
-
R
-
A
D
V
V
V
V
T
I
F
V
N
P
L
Q
F
E
R
P
D
D
L
A
H
Y
P
R
T
L
Q
E
D
C
E
K
L
T
R
H
G
A
D
L
V
F
A
P
A
A
A
D
I
Y
P
----
A
G
L
E
--
K
Q
--
T
Y
V
D
V
P
A
L
S
T
-
I
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
I
Q
P
D
V
A
C
F
G
E
K
D
Y
Q
Q
L
A
L
I
R
K
M
V
A
D
M
G
Y
D
I
N
I
V
G
V
P
T
V
R
A
K
D
G
L
A
L
S
S
R
N
G
Y
L
T
E
E
E
R
Q
I
A
P
Q
L
S
K
I
M
W
A
L
A
E
K
M
A
-
L
G
E
R
Q
I
D
A
L
L
E
E
A
A
A
Q
L
L
R
V
G
F
-------
T
P
D
E
L
F
----
I
R
D
A
E
T
L
Q
P
L
T
----
V
----------
D
----
S
-
Q
Q
A
V
I
L
M
A
A
W
L
G
K
A
R
L
I
D
N
Q
L
V
D
L
---
11
PsiBlast_PDB
82.27
39%
-91
- C5 -
3Q12
2
PANC_YERPE
A:
[4-286]
M
L
I
I
E
T
L
P
L
L
R
Q
Q
I
R
R
W
R
Q
E
G
K
R
I
A
L
V
P
T
M
G
N
L
H
E
G
H
M
T
L
V
D
E
A
K
T
-
R
-
A
D
V
V
V
V
T
I
F
V
N
P
L
Q
F
E
R
P
D
D
L
A
H
Y
P
R
T
L
Q
E
D
C
E
K
L
T
R
H
G
A
D
L
V
F
A
P
A
A
A
D
I
Y
P
----
A
G
L
E
--
K
Q
--
T
Y
V
D
VP
A
L
S
T
-
I
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
I
Q
P
D
V
A
C
F
G
E
K
D
Y
Q
Q
L
A
L
I
R
K
M
V
A
D
M
G
Y
D
I
N
I
V
G
V
P
T
V
R
A
K
D
G
L
A
L
S
S
R
N
G
Y
L
T
E
E
E
R
Q
I
A
P
Q
L
S
K
I
M
W
A
L
A
E
K
M
A
-
L
G
E
R
Q
I
D
A
L
L
E
E
A
A
A
Q
L
L
R
V
G
F
-------
T
P
D
E
L
F
----
I
R
D
A
E
T
L
Q
P
L
T
----
V
----------
D
----
S
-
Q
Q
A
V
I
L
M
A
A
W
L
G
K
A
R
L
I
D
N
Q
L
V
D
L
R
--
10
PsiBlast_PDB
82.22
39%
-92
- C5 -
3Q10
4
PANC_YERPE
A:
[4-286]
M
L
I
I
E
T
L
P
L
L
R
Q
Q
I
R
R
W
R
Q
E
G
K
R
I
A
L
V
P
T
M
G
N
L
H
E
G
H
M
T
L
V
D
E
A
K
T
-
R
-
A
D
V
V
V
V
T
I
F
V
N
P
L
Q
F
E
R
P
D
D
L
A
H
Y
P
R
T
L
Q
E
D
C
E
K
L
T
R
H
G
A
D
L
V
F
A
P
A
A
A
D
I
Y
P
----
A
G
L
E
--
K
Q
--
T
Y
V
D
VP
A
L
S
T
-
I
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
I
Q
P
D
V
A
C
F
G
E
K
D
Y
Q
Q
L
A
L
I
R
K
M
V
A
D
M
G
Y
D
I
N
I
V
G
V
P
T
V
R
A
K
D
G
L
A
L
S
S
R
N
G
Y
L
T
E
E
E
R
Q
I
A
P
Q
L
S
K
I
M
W
A
L
A
E
K
M
A
-
L
G
E
R
Q
I
D
A
L
L
E
E
A
A
A
Q
L
L
R
V
G
F
-------
T
P
D
E
L
F
----
I
R
D
A
E
T
L
Q
P
L
T
----
V
----------
D
----
S
-
Q
Q
A
V
I
L
M
A
A
W
L
G
K
A
R
L
I
D
N
Q
L
V
D
L
R
--
31
PsiBlast_CBE
82.13
39%
-91
- C5 -
3Q10
3
PANC_YERPE
B:
[4-286]
M
L
I
I
E
T
L
P
L
L
R
Q
Q
I
R
R
W
R
Q
E
G
K
R
I
A
L
V
P
T
M
G
N
L
H
E
G
H
M
T
L
V
D
E
A
K
T
-
R
-
A
D
V
V
V
V
T
I
F
V
N
P
L
Q
F
E
R
P
D
D
L
A
H
Y
P
R
T
L
Q
E
D
C
E
K
L
T
R
H
G
A
D
L
V
F
A
P
A
A
A
D
I
Y
P
----
A
G
L
E
--
K
Q
--
T
Y
V
D
V
P
A
L
S
T
-
I
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
I
Q
P
D
V
A
C
F
G
E
K
D
Y
Q
Q
L
A
L
I
R
K
M
V
A
D
M
G
Y
D
I
N
I
V
G
V
P
T
V
R
A
K
D
G
L
A
L
S
S
R
N
G
Y
L
T
E
E
E
R
Q
I
A
P
Q
L
S
K
I
M
W
A
L
A
E
K
M
A
-
L
G
E
R
Q
I
D
A
L
L
E
E
A
A
A
Q
L
L
R
V
G
F
-------
T
P
D
E
L
F
----
I
R
D
A
E
T
L
Q
P
L
T
----
V
----------
D
----
S
-
Q
Q
A
V
I
L
M
A
A
W
L
G
K
A
R
L
I
D
N
Q
L
V
D
L
R
--
113
HHSearch
80.43
34%
-96
- C5 -
3COV
8
PANC_MYCTU
A:
[12-289]
L
N
V
Y
S
A
P
G
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
-
V
P
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
A
A
A
V
-------
A
L
S
A
A
L
T
-
A
A
A
H
A
A
T
A
-
G
A
Q
A
A
---
L
D
A
A
R
A
V
L
D
A
A
P
-
G
V
-
A
V
D
Y
L
E
L
R
D
I
G
-
L
G
P
M
P
---------------
L
----
N
-
G
S
G
R
L
L
V
A
A
R
L
G
T
T
R
L
L
D
N
I
A
I
E
I
G
--
17
PsiBlast_PDB
75.54
42%
-103
- C5 -
4G5F
5
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
----
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
75.18
42%
-103
- C5 -
4FZJ
9
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
75.07
39%
-115
- C5 -
3Q10
2
PANC_YERPE
D:
[4-281]
M
L
I
I
E
T
L
P
L
L
R
Q
Q
I
R
R
W
R
Q
E
G
K
R
I
A
L
V
P
T
M
G
N
L
H
E
G
H
M
T
L
V
D
E
A
K
T
-
R
-
A
D
V
V
V
V
T
I
F
V
N
P
L
Q
F
E
R
P
D
D
L
A
H
Y
P
R
T
L
Q
E
D
C
E
K
L
T
R
H
G
A
D
L
V
F
A
P
A
A
A
D
I
Y
P
----
A
G
L
E
--
K
Q
--
T
Y
V
D
VP
A
L
S
T
-
I
L
-
E
G
A
S
R
P
G
H
F
R
G
V
S
T
I
V
S
K
L
F
N
L
I
Q
P
D
V
A
C
F
G
E
K
D
Y
Q
Q
L
A
L
I
R
K
M
V
A
D
M
G
Y
D
I
N
I
V
G
V
P
----------------------------------------------------------------------
T
P
D
E
L
F
----
I
R
----------------------------------
V
I
L
M
A
A
----
A
R
L
I
D
N
Q
-------
66
PsiBlast_CBE
74.99
42%
-102
- C5 -
4DE5
5
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
70
PsiBlast_CBE
74.98
42%
-100
- C5 -
4DDK
4
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
62
PsiBlast_CBE
74.91
42%
-104
- C5 -
4EFK
7
PANC_MYCTU
A:
[19-209]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
-------
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
94
PsiBlast_CBE
74.88
42%
-101
- C5 -
3IOB
6
PANC_MYCTU
A:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
82
PsiBlast_CBE
74.67
42%
-100
- C5 -
3IUE
15
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
100
PsiBlast_CBE
74.65
42%
-101
- C5 -
3IMC
8
PANC_MYCTU
A:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
68
PsiBlast_CBE
74.40
42%
-97
- C5 -
4DDM
6
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
96
PsiBlast_CBE
74.29
42%
-100
- C5 -
3IMG
6
PANC_MYCTU
A:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
74.25
42%
-102
- C5 -
4MUJ
9
PANC_MYCTO
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
74.21
42%
-101
- C5 -
4G5Y
6
PANC_MYCTU
A:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
64
PsiBlast_CBE
74.19
42%
-101
- C5 -
4EF6
9
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
88
PsiBlast_CBE
74.09
42%
-101
- C5 -
3IOE
5
PANC_MYCTU
A:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
98
PsiBlast_CBE
74.08
42%
-100
* C5 *
3IME
4
PANC_MYCTU
A:
[20-212]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
84
PsiBlast_CBE
74.08
42%
-102
- C5 -
3IUB
9
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
74.03
42%
-100
- C5 -
4MUG
6
PANC_MYCTO
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
72
PsiBlast_CBE
74.00
42%
-98
- C5 -
4DDH
6
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
76
PsiBlast_CBE
73.78
42%
-100
- C5 -
3IVX
12
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
73.71
42%
-98
- C5 -
1MOP
7
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
73.64
42%
-99
- C5 -
4MQ6
10
PANC_MYCTO
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
73.49
42%
-100
- C5 -
4MUH
9
PANC_MYCTO
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
87
PsiBlast_CBE
73.46
42%
-104
- C5 -
3IOE
4
PANC_MYCTU
B:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
-------
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
78
PsiBlast_CBE
73.44
42%
-100
- C5 -
3IVG
9
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
86
PsiBlast_CBE
73.43
42%
-98
- C5 -
3ISJ
6
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
73.40
42%
-99
- C5 -
4MUL
12
PANC_MYCTO
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
117
HHSearch
73.17
36%
-81
- C5 -
3N8H
5
PANC_FRATT
A:
[4-261]
M
I
I
A
D
N
I
K
Q
F
H
S
I
R
N
S
L
-
I
K
Q
Q
K
I
G
F
V
P
T
M
G
A
L
H
N
G
H
I
S
L
I
K
K
A
K
S
-
E
-
N
D
V
V
I
V
S
I
F
V
N
P
T
Q
F
N
N
P
N
D
Y
Q
T
Y
P
N
Q
L
Q
Q
D
I
Q
I
L
A
S
L
D
V
D
V
L
F
N
P
S
E
K
D
I
Y
P
----
D
G
N
L
--
L
R
--
I
E
P
K
L-
E
I
A
N
-
I
L
-
E
G
K
S
R
P
G
H
F
S
G
M
L
T
V
V
L
K
L
L
Q
I
T
K
P
N
N
L
Y
L
G
E
K
D
Y
Q
Q
V
M
L
I
K
Q
L
V
K
D
F
F
I
N
T
K
I
I
V
C
P
T
Q
R
Q
P
S
G
L
P
L
S
S
R
N
K
N
L
T
S
T
D
I
E
I
A
N
-------
K
I
Y
E
I
L
R
-
Q
D
D
F
S
N
L
E
-
E
----------
L
T
N
K
I
N
-
S
T
-
G
A
-
K
L
Q
Y
I
Q
K
--------------------------------
L
N
N
R
I
F
L
A
F
Y
I
G
K
V
R
L
I
D
N
F
L
K
E
T
G
--
80
PsiBlast_CBE
72.99
42%
-101
- C5 -
3IVC
9
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
90
PsiBlast_CBE
72.74
42%
-102
- C5 -
3IOD
6
PANC_MYCTU
A:
[20-212]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
-----
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
72.67
42%
-99
- C5 -
4MUN
13
PANC_MYCTO
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
---
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
72.64
42%
-97
- C5 -
1N2B
7
PANC_MYCTU
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
G
G
D
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
56
PsiBlast_CBE
72.29
42%
-110
- C5 -
4MUE
5
PANC_MYCTO
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
-----------
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
83
PsiBlast_CBE
72.16
42%
-106
- C5 -
3IUB
10
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
----------
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
72.13
42%
-108
- C5 -
4MUI
6
PANC_MYCTO
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
-----
L
D
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
72.02
42%
-101
- C5 -
4MUF
3
PANC_MYCTO
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
--------
A
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
71.97
42%
-108
- C5 -
4FZJ
9
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
89
PsiBlast_CBE
71.73
42%
-110
- C5 -
3IOD
5
PANC_MYCTU
B:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
---------------
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
69
PsiBlast_CBE
71.69
42%
-102
- C5 -
4DDK
5
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
G
A
------
Y
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
38
PsiBlast_CBE
71.58
42%
-111
- C5 -
4G5F
5
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
---------------
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
53
PsiBlast_CBE
71.54
42%
-112
- C5 -
4MUF
3
PANC_MYCTO
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
---------------
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
71.41
42%
-113
- C5 -
4MQ6
8
PANC_MYCTO
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
---------------
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
71.40
42%
-116
- C5 -
4MUL
9
PANC_MYCTO
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
---------------
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
81
PsiBlast_CBE
71.16
42%
-107
- C5 -
3IUE
12
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
----------
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
71.14
42%
-110
- C5 -
4MUH
9
PANC_MYCTO
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
--------------
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
95
PsiBlast_CBE
70.99
42%
-113
- C5 -
3IMG
5
PANC_MYCTU
B:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
---------------
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
99
PsiBlast_CBE
70.96
42%
-105
- C5 -
3IMC
6
PANC_MYCTU
B:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
70.94
42%
-107
- C5 -
4MUG
7
PANC_MYCTO
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
--------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
85
PsiBlast_CBE
70.83
42%
-107
- C5 -
3ISJ
7
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
---------
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
43
PsiBlast_CBE
70.72
42%
-112
- C5 -
4MUK
7
PANC_MYCTO
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
----------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
70.66
42%
-113
- C5 -
4MUI
7
PANC_MYCTO
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
---------------
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
44
PsiBlast_CBE
70.57
42%
-112
- C5 -
4MUK
8
PANC_MYCTO
A:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
---------------
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
79
PsiBlast_CBE
70.41
42%
-104
- C5 -
3IVC
9
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
-----------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
70.19
42%
-104
- C5 -
4MUE
3
PANC_MYCTO
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
45
PsiBlast_CBE
70.14
42%
-114
- C5 -
4MUJ
8
PANC_MYCTO
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
----------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
67
PsiBlast_CBE
70.06
42%
-106
- C5 -
4DDM
6
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
73
PsiBlast_CBE
70.05
42%
-106
- C5 -
3LE8
5
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
------------
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
75
PsiBlast_CBE
70.02
42%
-106
- C5 -
3IVX
9
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
97
PsiBlast_CBE
70.00
42%
-110
- C5 -
3IME
3
PANC_MYCTU
B:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
--------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
61
PsiBlast_CBE
69.95
42%
-110
- C5 -
4EFK
9
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
--------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
93
PsiBlast_CBE
69.87
42%
-105
- C5 -
3IOB
5
PANC_MYCTU
B:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
77
PsiBlast_CBE
69.85
42%
-107
- C5 -
3IVG
6
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
71
PsiBlast_CBE
69.85
42%
-106
- C5 -
4DDH
6
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
F
---------
P
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
91
PsiBlast_CBE
69.82
42%
-110
- C5 -
3IOC
2
PANC_MYCTU
B:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
-------------
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
57
PsiBlast_CBE
69.76
42%
-111
- C5 -
4G5Y
7
PANC_MYCTU
B:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
---------------
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
69.74
42%
-109
- C5 -
4MUN
10
PANC_MYCTO
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
--------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
63
PsiBlast_CBE
69.53
42%
-106
- C5 -
4EF6
10
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
-----------
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
65
PsiBlast_CBE
69.16
42%
-107
- C5 -
4DE5
5
PANC_MYCTU
B:
[19-207]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
-----------
R
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
92
PsiBlast_CBE
68.83
42%
-102
- C5 -
3IOC
3
PANC_MYCTU
A:
[20-208]
--------
D
V
A
D
V
S
R
A
L
R
L
T
G
R
R
V
M
L
V
P
T
M
G
A
L
H
E
G
H
L
A
L
V
R
A
A
K
R
V
P
-
G
S
V
V
V
V
S
I
F
V
N
P
M
Q
------------
T
P
D
D
D
L
A
Q
L
R
A
E
G
V
E
I
A
F
T
P
T
T
A
A
M
Y
P
----
D
G
L
R
--
T
T
--
V
Q
P
G
--
P
L
A
A
-
E
L
-
E
G
G
P
R
P
T
H
F
A
G
V
L
T
V
V
L
K
L
L
Q
I
V
R
P
D
R
V
F
F
G
E
K
D
Y
Q
Q
L
V
L
I
R
Q
L
V
A
D
F
N
L
D
V
A
V
V
G
V
P
T
V
R
E
A
D
G
L
A
M
S
S
R
N
R
Y
L
D
P
A
Q
R
----------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
67.22
37%
-84
- C5 -
3QTT
4
PANC_FRATT
A:
[10-210]
---
I
K
Q
F
H
S
I
R
N
S
L
I
K
Q
Q
K
----
I
G
F
V
P
T
M
G
A
L
H
N
G
H
I
S
L
I
K
K
A
K
S
-
E
-
N
D
V
V
I
V
S
I
F
V
N
P
T
Q
F
N
N
P
N
D
Y
Q
T
Y
P
N
Q
L
Q
Q
D
I
Q
I
L
A
S
L
D
V
D
V
L
F
N
P
S
E
K
D
I
Y
P
DGNL
L
R
I
E
--
P
K
--
L
E
I
-----
A
N
-
I
L
-
E
G
K
S
R
P
G
H
F
S
G
M
L
T
V
V
L
K
L
L
Q
I
T
K
P
N
N
L
Y
L
G
E
K
D
Y
Q
Q
V
M
L
I
K
Q
L
V
K
D
F
F
I
N
T
K
I
I
V
C
P
T
Q
R
Q
P
S
G
L
P
L
S
S
R
N
K
N
L
T
S
T
D
I
E
I
A
N
-------
K
I
Y
E
I
L
R
----------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
67.11
37%
-83
- C5 -
3N8H
5
PANC_FRATT
A:
[10-210]
---
I
K
Q
F
H
S
I
R
N
S
L
I
K
Q
Q
K
----
I
G
F
V
P
T
M
G
A
L
H
N
G
H
I
S
L
I
K
K
A
K
S
-
E
-
N
D
V
V
I
V
S
I
F
V
N
P
T
Q
F
N
N
P
N
D
Y
Q
T
Y
P
N
Q
L
Q
Q
D
I
Q
I
L
A
S
L
D
V
D
V
L
F
N
P
S
E
K
D
I
Y
P
DGNL
L
R
I
E
--
P
K
--
L
E
I
-----
A
N
-
I
L
-
E
G
K
S
R
P
G
H
F
S
G
M
L
T
V
V
L
K
L
L
Q
I
T
K
P
N
N
L
Y
L
G
E
K
D
Y
Q
Q
V
M
L
I
K
Q
L
V
K
D
F
F
I
N
T
K
I
I
V
C
P
T
Q
R
Q
P
S
G
L
P
L
S
S
R
N
K
N
L
T
S
T
D
I
E
I
A
N
-------
K
I
Y
E
I
L
R
----------------------------------------------------------------------------------------------------