@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1995: (2016-03-30 )
MTIAKMIDHTALKPDTTKEQILTLTKEAREYGFASVCVNPTWVKLSAEQLAGAESVVCTVIGFPLGANTPEVKAFEVKDAIQNGAKEVDMVINIGALKDKDDELVERDIRAVVDVAKGKALVKVIIETCLLTDEEKVRACEIAVKAGTDFVKTSTGFSTGGATAEDIALMRKTVGPNIGVKASGGVRTKEDVEKMIEAGATRIGASAGVAIVSGEKPAKPDNY
Atome Classification :
(29 SA)
---------.........10........20........30--........40........50--.....---....60........70........80........90........100.......--110.......-120.......130--..----...-..-.--140.......150......-.-160.......170--..-----..---.-----...180.......190.......200.....--------..210..---.....220.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------M
T
I
A
K
M
I
D
HTALKPDT
T
K
E
Q
I
L
T
L
T
K
E
A
R
EY--G
F
A
S
VCVNP
T
W
V
K
L
S
A
E
Q
L---AGA
E
S
---
V
V
C
T
V
IGFPLGANTPE
V
K
A
F
E
V
K
D
A
I
QNGAK
E
V
D
M
V
I
N
IGALKDK
D
D
E
L
V
E
R
D
I
--
R
A
V
V
D
V
AK
G
K
-
A
L
V
K
V
I
I
E
T
CLL---T
D
----
E
E
K-
V
R
-
A
--
C
E
I
A
V
KAGT
D
F
V
K
TSTGFS-T-GGA
T
A
E
D
I
A
L
M
R
---
K
T-----VG---P-----NI
G
V
KASGGVR
T
K
E
D
V
E
K
M
I
E
AGATRIGASA--------
G
V
A
I
VSG---EKPAKPDNY
22
PsiBlast_CBE
97.45
63%
-94
- C2 -
3NGJ
5
?
C:
[26-237]
----------
T
L
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
F
A
S
V
C
V
N
P
T
W
V
P
L
C
A
E
L
L
---
K
G
T
G
V
---
K
V
C
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
I
N
I
G
M
V
K
A
K
K
Y
D
D
V
E
K
D
V
--
K
A
V
V
D
-
A
S
G
K
-
A
L
T
K
V
I
I
E
C
C
Y
L
---
T
N
----
E
E
K
-
V
E
-
V
--
C
K
R
C
V
A
A
G
A
E
Y
V
K
T
S
T
G
F
G
-
T
-
H
G
A
T
P
E
D
V
K
L
M
K
---
D
T
-----
V
G
---
D
-----
K
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
G
A
S
R
I
G
A
S
A
--------
G
I
A
I
L
N
G
------------
23
PsiBlast_CBE
97.11
63%
-95
- C2 -
3NGJ
5
?
B:
[26-237]
----------
T
L
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
F
A
S
V
C
V
N
P
T
W
V
P
L
C
A
E
L
L
---
K
G
T
G
V
---
K
V
C
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
I
N
I
G
M
V
K
A
K
K
Y
D
D
V
E
K
D
V
--
K
A
V
V
D
-
A
S
G
K
-
A
L
T
K
V
I
I
E
C
C
Y
L
---
T
N
----
E
E
K
-
V
E
-
V
--
C
K
R
C
V
A
A
G
A
E
Y
V
K
T
S
T
G
F
G
-
T
-
H
G
A
T
P
E
D
V
K
L
M
K
---
D
T
-----
V
G
---
D
-----
K
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
G
A
S
R
I
G
A
S
A
--------
G
I
A
I
L
N
G
------------
1
PsiBlast_PDB
97.02
63%
-93
- C2 -
3NGJ
3
?
A:
[26-237]
----------
T
L
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
F
A
S
V
C
V
N
P
T
W
V
P
L
C
A
E
L
L
---
K
G
T
G
V
---
K
V
C
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
I
N
I
G
M
V
K
A
K
K
Y
D
D
V
E
K
D
V
--
K
A
V
V
D
-
A
S
G
K
-
A
L
T
K
V
I
I
E
C
C
Y
L
---
T
N
----
E
E
K
-
V
E
-
V
--
C
K
R
C
V
A
A
G
A
E
Y
V
K
T
S
T
G
F
G
-
T
-
H
G
A
T
P
E
D
V
K
L
M
K
---
D
T
-----
V
G
---
D
-----
K
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
G
A
S
R
I
G
A
S
A
--------
G
I
A
I
L
N
G
------------
48
HHSearch
96.77
61%
-94
- C2 -
3NGJ
3
?
A:
[25-238]
---------
A
T
L
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
F
A
S
V
C
V
N
P
T
W
V
P
L
C
A
E
L
L
---
K
G
T
G
V
---
K
V
C
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
I
N
I
G
M
V
K
A
K
K
Y
D
D
V
E
K
D
V
--
K
A
V
V
D
A
S
G
K
A
--
L
T
K
V
I
I
E
C
C
Y
L
---
T
N
----
E
E
K
-
V
E
-
V
--
C
K
R
C
V
A
A
G
A
E
Y
V
K
T
S
T
G
F
G
-
T
-
H
G
A
T
P
E
D
V
K
L
M
K
---
D
T
-----
V
G
---
D
-----
K
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
G
A
S
R
I
G
A
S
A
--------
G
I
A
I
L
N
G
---
I
--------
21
PsiBlast_CBE
96.38
63%
-95
- C2 -
3NGJ
5
?
D:
[26-237]
----------
T
L
A
K
Y
I
D
H
T
L
L
K
A
D
A
T
E
E
Q
I
R
K
L
C
S
E
A
A
E
Y
--
K
F
A
S
V
C
V
N
P
T
W
V
P
L
C
A
E
L
L
---
K
G
T
G
V
---
K
V
C
T
V
I
G
F
P
L
G
A
T
P
S
E
V
K
A
Y
E
T
K
V
A
V
E
Q
G
A
E
E
V
D
M
V
I
N
I
G
M
V
K
A
K
K
Y
D
D
V
E
K
D
V
--
K
A
V
V
D
-
A
S
G
K
-
A
L
T
K
V
I
I
E
C
C
Y
L
---
T
N
----
E
E
K
-
V
E
-
V
--
C
K
R
C
V
A
A
G
A
E
Y
V
K
T
S
T
G
F
G
-
T
-
H
G
A
T
P
E
D
V
K
L
M
K
---
D
T
-----
V
G
---
D
-----
K
A
L
V
K
A
A
G
G
I
R
T
F
D
D
A
M
K
M
I
N
N
G
A
S
R
I
G
A
S
A
--------
G
I
A
I
L
N
G
------------
46
HHSearch
93.49
56%
-89
- C2 -
3R12
3
DEOC_THEMA
A:
[42-259]
----------
D
V
K
S
A
I
E
H
T
N
L
K
P
F
A
T
P
D
D
I
K
K
L
C
L
E
A
R
E
N
--
R
F
H
G
V
C
V
N
P
C
Y
V
K
L
A
R
E
E
L
---
E
G
T
D
V
---
K
V
V
T
V
V
G
F
P
L
G
A
N
E
T
R
T
K
A
H
E
A
I
F
A
V
E
S
G
A
D
E
I
D
M
V
I
N
V
G
M
L
K
A
K
E
W
E
Y
V
Y
E
D
I
--
R
S
V
V
E
S
V
K
G
K
--
V
V
K
V
I
I
E
T
C
Y
L
---
D
T
----
E
E
K
-
I
A
-
A
--
C
V
I
S
K
L
A
G
A
H
F
V
K
T
S
T
G
F
G
-
T
-
G
G
A
T
A
E
D
V
H
L
M
K
---
W
I
-----
V
G
---
D
-----
E
M
G
V
K
A
S
G
G
I
R
T
F
E
D
A
V
K
M
I
M
Y
G
A
D
R
I
G
T
S
S
--------
G
V
K
I
V
Q
G
---
G
E
E
R
Y
G
---
3
PsiBlast_PDB
90.91
57%
-90
- C2 -
3R13
5
DEOC_THEMA
A:
[47-253]
---------------
I
E
H
T
N
L
K
P
F
A
T
P
D
D
I
K
K
L
C
L
E
A
R
E
N
--
R
F
H
G
V
C
V
N
P
C
Y
V
K
L
A
R
E
E
L
---
E
G
T
D
V
---
K
V
V
T
V
V
G
F
P
L
G
A
N
E
T
R
T
K
A
H
E
A
I
F
A
V
E
S
G
A
D
E
I
D
M
V
I
N
V
G
M
L
K
A
K
E
W
E
Y
V
Y
E
D
I
--
R
S
V
V
E
S
V
K
G
K
--
V
V
K
V
I
I
E
T
C
Y
L
---
D
T
----
E
E
K
-
I
A
-
A
--
C
V
I
S
K
L
A
G
A
H
F
V
K
T
S
T
G
F
G
-
T
-
G
G
A
T
A
E
D
V
H
L
M
K
---
W
I
-----
V
G
---
D
-----
E
M
G
V
K
A
S
G
G
I
R
T
F
E
D
A
V
K
M
I
M
Y
G
A
D
R
I
G
T
S
S
--------
G
V
K
I
V
Q
G
------------
2
PsiBlast_PDB
90.88
57%
-91
- C2 -
3R12
3
DEOC_THEMA
A:
[47-253]
---------------
I
E
H
T
N
L
K
P
F
A
T
P
D
D
I
K
K
L
C
L
E
A
R
E
N
--
R
F
H
G
V
C
V
N
P
C
Y
V
K
L
A
R
E
E
L
---
E
G
T
D
V
---
K
V
V
T
V
V
G
F
P
L
G
A
N
E
T
R
T
K
A
H
E
A
I
F
A
V
E
S
G
A
D
E
I
D
M
V
I
N
V
G
M
L
K
A
K
E
W
E
Y
V
Y
E
D
I
--
R
S
V
V
E
S
V
K
G
K
--
V
V
K
V
I
I
E
T
C
Y
L
---
D
T
----
E
E
K
-
I
A
-
A
--
C
V
I
S
K
L
A
G
A
H
F
V
K
T
S
T
G
F
G
-
T
-
G
G
A
T
A
E
D
V
H
L
M
K
---
W
I
-----
V
G
---
D
-----
E
M
G
V
K
A
S
G
G
I
R
T
F
E
D
A
V
K
M
I
M
Y
G
A
D
R
I
G
T
S
S
--------
G
V
K
I
V
Q
G
------------
24
PsiBlast_CBE
87.91
45%
-88
- C2 -
3OA3
1
?
B:
[56-273]
---------
V
S
I
A
Q
I
I
D
H
T
Q
L
S
L
S
A
T
G
S
Q
I
D
V
L
C
A
E
A
K
E
Y
--
G
F
A
T
V
C
V
R
P
D
Y
V
S
R
A
V
Q
Y
L
---
Q
G
T
Q
V
---
G
V
T
C
V
I
G
F
H
E
G
T
Y
S
T
D
Q
K
V
S
E
A
K
R
A
M
Q
N
G
A
S
E
L
D
M
V
M
N
Y
P
W
L
S
E
K
R
Y
T
D
V
F
Q
D
I
--
R
A
V
R
L
A
A
K
-
D
-
A
I
L
K
V
I
L
E
T
S
Q
L
---
T
A
----
D
E
I
-
I
A
-
G
--
C
V
L
S
S
L
A
G
A
D
Y
V
K
T
S
T
G
F
N
-
G
-
P
G
A
S
I
E
N
V
S
L
M
S
AVC
D
S
-----
L
Q
---
S
-----
E
T
R
V
K
A
S
G
G
I
R
T
I
E
D
C
V
K
M
V
R
A
G
A
E
R
L
G
A
S
A
--------
G
V
K
I
V
N
E
TR----------
45
HHSearch
86.63
47%
-89
- C2 -
3OA3
1
?
A:
[57-274]
----------
S
I
A
Q
I
I
D
H
T
Q
L
S
L
S
A
T
G
S
Q
I
D
V
L
C
A
E
A
K
E
Y
--
G
F
A
T
V
C
V
R
P
D
Y
V
S
R
A
V
Q
Y
L
---
Q
G
T
Q
V
---
G
V
T
C
V
I
G
F
H
E
G
T
Y
S
T
D
Q
K
V
S
E
A
K
R
A
M
Q
N
G
A
S
E
L
D
M
V
M
N
Y
P
W
L
S
E
K
R
Y
T
D
V
F
Q
D
I
--
R
A
V
R
L
A
A
K
D
A
--
I
L
K
V
I
L
E
T
S
Q
L
---
T
A
----
D
E
I
-
I
A
-
G
--
C
V
L
S
S
L
A
G
A
D
Y
V
K
T
S
T
G
F
N
-
G
-
P
G
A
S
I
E
N
V
S
L
M
S
---
A
V
-----
C
D
S
LQ
S
-----
E
T
R
V
K
A
S
G
G
I
R
T
I
E
D
C
V
K
M
V
R
A
G
A
E
R
L
G
A
S
A
--------
G
V
K
I
V
N
E
---
T
R
L
------
4
PsiBlast_PDB
86.39
45%
-92
- C2 -
3OA3
1
?
A:
[56-274]
---------
V
S
I
A
Q
I
I
D
H
T
Q
L
S
L
S
A
T
G
S
Q
I
D
V
L
C
A
E
A
K
E
Y
--
G
F
A
T
V
C
V
R
P
D
Y
V
S
R
A
V
Q
Y
L
---
Q
G
T
Q
V
---
G
V
T
C
V
I
G
F
H
E
G
T
Y
S
T
D
Q
K
V
S
E
A
K
R
A
M
Q
N
G
A
S
E
L
D
M
V
M
N
Y
P
W
L
S
E
K
R
Y
T
D
V
F
Q
D
I
--
R
A
V
R
L
A
A
K
-
D
-
A
I
L
K
V
I
L
E
T
S
Q
L
---
T
A
----
D
E
I
-
I
A
-
G
--
C
V
L
S
S
L
A
G
A
D
Y
V
K
T
S
T
G
F
N
-
G
-
P
G
A
S
I
E
N
V
S
L
M
S
A
V
C
D
S
-----
L
Q
---
S
-----
E
T
R
V
K
A
S
G
G
I
R
T
I
E
D
C
V
K
M
V
R
A
G
A
E
R
L
G
A
S
A
--------
G
V
K
I
V
N
E
T
R
L---------
6
PsiBlast_PDB
85.59
44%
-83
- C2 -
1UB3
1
DEOC_THET8
A:
[2-212]
----------
D
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
F
Y
G
L
C
I
P
P
S
Y
V
A
W
V
R
A
R
Y
---
P
H
A
P
F
---
R
L
V
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
L
H
L
G
R
A
K
A
G
D
L
D
Y
L
E
A
E
V
--
R
A
V
R
E
-
A
V
P
Q
-
A
V
L
K
V
I
L
E
T
G
Y
F
---
S
P
----
E
E
I
-
A
R
-
L
--
A
E
A
A
I
R
G
G
A
D
F
L
K
T
S
T
G
F
G
-
P
-
R
G
A
S
L
E
D
V
A
L
L
V
---
R
V
-----
A
Q
---
G
-----
R
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
G
A
S
R
L
G
T
S
S
--------
G
V
A
L
V
A
-------------
5
PsiBlast_PDB
85.06
44%
-85
- C2 -
1J2W
-
DEOC_THET8
A:
[1-212]
---------
M
D
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
F
Y
G
L
C
I
P
P
S
Y
V
A
W
V
R
A
R
Y
---
P
H
A
P
F
---
R
L
V
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
L
H
L
G
R
A
K
A
G
D
L
D
Y
L
E
A
E
V
--
R
A
V
R
E
-
A
V
P
Q
-
A
V
L
K
V
I
L
E
T
G
Y
F
---
S
P
----
E
E
I
-
A
R
-
L
--
A
E
A
A
I
R
G
G
A
D
F
L
K
T
S
T
G
F
G
-
P
-
R
G
A
S
L
E
D
V
A
L
L
V
---
R
V
-----
A
Q
---
G
-----
R
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
G
A
S
R
L
G
T
S
S
--------
G
V
A
L
V
A
-------------
27
PsiBlast_CBE
84.73
44%
-87
- C2 -
1UB3
1
DEOC_THET8
B:
[1-211]
---------
M
D
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
F
Y
G
L
C
I
P
P
S
Y
V
A
W
V
R
A
R
Y
---
P
H
A
P
F
---
R
L
V
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
L
H
L
G
R
A
K
A
G
D
L
D
Y
L
E
A
E
V
--
R
A
V
R
E
-
A
V
P
Q
-
A
V
L
K
V
I
L
E
T
G
Y
F
---
S
P
----
E
E
I
-
A
R
-
L
--
A
E
A
A
I
R
G
G
A
D
F
L
K
T
S
T
G
F
G
-
P
-
R
G
A
S
L
E
D
V
A
L
L
V
---
R
V
-----
A
Q
---
G
-----
R
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
G
A
S
R
L
G
T
S
S
--------
G
V
A
L
V
--------------
25
PsiBlast_CBE
84.73
44%
-84
- C2 -
1UB3
1
DEOC_THET8
D:
[2-212]
----------
D
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
F
Y
G
L
C
I
P
P
S
Y
V
A
W
V
R
A
R
Y
---
P
H
A
P
F
---
R
L
V
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
L
H
L
G
R
A
K
A
G
D
L
D
Y
L
E
A
E
V
--
R
A
V
R
E
-
A
V
P
Q
-
A
V
L
K
V
I
L
E
T
G
Y
F
---
S
P
----
E
E
I
-
A
R
-
L
--
A
E
A
A
I
R
G
G
A
D
F
L
K
T
S
T
G
F
G
-
P
-
R
G
A
S
L
E
D
V
A
L
L
V
---
R
V
-----
A
Q
---
G
-----
R
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
G
A
S
R
L
G
T
S
S
--------
G
V
A
L
V
A
-------------
47
HHSearch
84.60
43%
-84
- C2 -
1UB3
1
DEOC_THET8
A:
[2-212]
----------
D
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
F
Y
G
L
C
I
P
P
S
Y
V
A
W
V
R
A
R
Y
---
P
H
A
P
F
---
R
L
V
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
L
H
L
G
R
A
K
A
G
D
L
D
Y
L
E
A
E
V
--
R
A
V
R
E
A
V
P
Q
A
--
V
L
K
V
I
L
E
T
G
Y
F
---
S
P
----
E
E
I
-
A
R
-
L
--
A
E
A
A
I
R
G
G
A
D
F
L
K
T
S
T
G
F
G
-
P
-
R
G
A
S
L
E
D
V
A
L
L
V
---
R
V
-----
A
Q
---
G
-----
R
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
G
A
S
R
L
G
T
S
S
--------
G
V
A
L
V
A
-------------
26
PsiBlast_CBE
84.12
44%
-85
- C2 -
1UB3
1
DEOC_THET8
C:
[2-211]
----------
D
L
A
A
H
I
D
H
T
L
L
K
P
T
A
T
L
E
E
V
A
K
A
A
E
E
A
L
E
Y
--
G
F
Y
G
L
C
I
P
P
S
Y
V
A
W
V
R
A
R
Y
---
P
H
A
P
F
---
R
L
V
T
V
V
G
F
P
L
G
Y
Q
E
K
E
V
K
A
L
E
A
A
L
A
C
A
R
G
A
D
E
V
D
M
V
L
H
L
G
R
A
K
A
G
D
L
D
Y
L
E
A
E
V
--
R
A
V
R
E
-
A
V
P
Q
-
A
V
L
K
V
I
L
E
T
G
Y
F
---
S
P
----
E
E
I
-
A
R
-
L
--
A
E
A
A
I
R
G
G
A
D
F
L
K
T
S
T
G
F
G
-
P
-
R
G
A
S
L
E
D
V
A
L
L
V
---
R
V
-----
A
Q
---
G
-----
R
A
Q
V
K
A
A
G
G
I
R
D
R
E
T
A
L
R
M
L
K
A
G
A
S
R
L
G
T
S
S
--------
G
V
A
L
V
--------------
32
PsiBlast_CBE
83.01
46%
-88
- C2 -
3NG3
2
DEOC_MYCA1
B:
[12-225]
-----------
L
A
A
F
V
D
H
T
L
L
K
P
E
A
T
A
A
D
V
A
A
L
V
T
E
A
A
E
L
--
G
V
Y
A
V
C
V
S
P
P
M
V
P
A
A
V
Q
-----
A
-------
R
V
A
S
V
A
G
F
P
S
G
K
H
V
S
A
V
K
A
H
E
A
A
L
A
V
A
S
G
A
A
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
L
D
G
V
R
A
D
I
--
A
A
V
R
G
-
A
V
G
G
-
A
V
L
K
V
I
V
E
S
S
A
L
L
A
L
A
D
----
E
H
T
L
V
R
-
V
--
C
R
A
A
E
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
-
G
G
A
S
V
R
A
V
A
L
M
A
---
E
A
-----
V
G
---
G
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
A
D
A
L
A
M
L
D
A
G
A
T
R
L
G
L
S
G
--------
T
R
A
V
L
D
G
------------
29
PsiBlast_CBE
82.78
42%
-89
- C2 -
3NDO
3
?
B:
[13-227]
-----------
V
A
A
L
V
D
H
T
L
L
K
P
E
A
T
P
S
D
V
T
A
L
V
D
E
A
A
D
L
--
G
V
F
A
V
C
V
S
P
P
L
V
S
V
A
A
-
G
V
---
A
P
S
G
L
---
A
I
A
A
V
A
G
F
P
S
G
K
H
V
P
G
I
K
A
T
E
A
E
L
A
V
A
A
G
A
T
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
L
D
A
V
S
A
D
I
--
T
A
V
R
K
A
V
R
-
A
-
A
T
L
K
V
I
V
E
S
A
A
L
---
L
E
FS--
G
E
P
-
L
L
-
A
DV
C
R
V
A
R
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
-
G
G
A
S
V
Q
A
V
E
I
M
A
---
R
T
-----
V
G
---
E
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
E
Q
A
A
A
M
L
D
A
G
A
T
R
L
G
L
S
G
--------
S
R
A
V
L
D
G
------------
8
PsiBlast_PDB
82.15
42%
-89
- C2 -
3NDO
4
?
A:
[13-227]
-----------
V
A
A
L
V
D
H
T
L
L
K
P
E
A
T
P
S
D
V
T
A
L
V
D
E
A
A
D
L
--
G
V
F
A
V
C
V
S
P
P
L
V
S
V
A
A
-
G
V
---
A
P
S
G
L
---
A
I
A
A
V
A
G
F
P
S
G
K
H
V
P
G
I
K
A
T
E
A
E
L
A
V
A
A
G
A
T
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
L
D
A
V
S
A
D
I
--
T
A
V
R
K
A
V
R
-
A
-
A
T
L
K
V
I
V
E
S
A
A
L
---
L
E
F
S--
G
E
P
-
L
L
-
A
D
V
C
R
V
A
R
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
-
G
G
A
S
V
Q
A
V
E
I
M
A
---
R
T
-----
V
G
---
E
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
E
Q
A
A
A
M
L
D
A
G
A
T
R
L
G
L
S
G
--------
S
R
A
V
L
D
G
------------
49
HHSearch
81.76
41%
-83
- C2 -
3NDO
4
?
A:
[11-230]
---------
A
Q
V
A
A
L
V
D
H
T
L
L
K
P
E
A
T
P
S
D
V
T
A
L
V
D
E
A
A
D
L
--
G
V
F
A
V
C
V
S
P
P
L
V
S
V
A
A
G
V
A
---
P
-
S
G
L
---
A
I
A
A
V
A
G
F
P
S
G
K
H
V
P
G
I
K
A
T
E
A
E
L
A
V
A
A
G
A
T
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
L
D
A
V
S
A
D
I
--
T
A
V
R
K
A
V
R
A
A
--
T
L
K
V
I
V
E
S
A
A
L
---
L
E
F
SG
E
P
L
L
-
A
D
-
V
--
C
R
V
A
R
D
A
G
A
D
F
V
K
T
S
T
G
F
H
-
P
S
G
G
A
S
V
Q
A
V
E
I
M
A
---
R
T
-----
V
G
---
E
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
E
Q
A
A
A
M
L
D
A
G
A
T
R
L
G
L
S
G
--------
S
R
A
V
L
D
G
---
F
G
S
------
30
PsiBlast_CBE
80.82
46%
-86
- C2 -
3NG3
2
DEOC_MYCA1
D:
[12-225]
-----------
L
A
A
F
V
D
H
T
L
L
K
P
E
A
T
A
A
D
V
A
A
L
V
T
E
A
A
E
L
--
G
V
Y
A
V
C
V
S
P
P
M
V
P
A
A
V
Q
-----
A
--
G
V
---
R
V
A
S
V
A
G
F
P
S
G
K
H
V
S
A
V
K
A
H
E
A
A
L
A
V
A
S
G
A
A
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
L
D
G
V
R
A
D
I
--
A
A
V
R
G
-
A
V
G
G
-
A
V
L
K
V
I
V
E
S
S
A
L
LAL
A
D
----
E
H
T
L
V
R
-
V
--
C
R
A
A
E
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
-
G
G
A
S
V
R
A
V
A
L
M
A
---
E
A
-----
V
G
---
G
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
A
D
A
L
A
M
L
D
A
G
A
T
R
L
G
L
S
G
--------
T
R
A
V
L
D
G
------------
31
PsiBlast_CBE
80.77
46%
-89
- C2 -
3NG3
4
DEOC_MYCA1
C:
[12-225]
-----------
L
A
A
F
V
D
H
T
L
L
K
P
E
A
T
A
A
D
V
A
A
L
V
T
E
A
A
E
L
--
G
V
Y
A
V
C
V
S
P
P
M
V
P
A
A
V
Q
-----
A
G
A
G
V
---
R
V
A
S
V
A
G
F
P
S
G
K
H
V
S
A
V
K
A
H
E
A
A
L
A
V
A
S
G
A
A
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
L
D
G
V
R
A
D
I
--
A
A
V
R
G
-
A
V
G
G
-
A
V
L
K
V
I
V
E
S
S
A
L
L
A
L
A
D
----
E
H
T
L
V
R
-
V
--
C
R
A
A
E
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
-
G
G
A
S
V
R
A
V
A
L
M
A
---
E
A
-----
V
G
---
G
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
A
D
A
L
A
M
L
D
A
G
A
T
R
L
G
L
S
G
--------
T
R
A
V
L
D
G
------------
9
PsiBlast_PDB
79.77
46%
-88
- C2 -
3NG3
2
DEOC_MYCA1
A:
[12-225]
-----------
L
A
A
F
V
D
H
T
L
L
K
P
E
A
T
A
A
D
V
A
A
L
V
T
E
A
A
E
L
--
G
V
Y
A
V
C
V
S
P
P
M
V
P
A
A
V
Q
-----
A
G
A
-----
R
V
A
S
V
A
G
F
P
S
G
K
H
V
S
A
V
K
A
H
E
A
A
L
A
V
A
S
G
A
A
E
I
D
M
V
I
D
V
G
A
A
L
A
G
D
L
D
G
V
R
A
D
I
--
A
A
V
R
G
-
A
V
G
G
-
A
V
L
K
V
I
V
E
S
S
A
L
L
A
L
A
D
----
E
H
T
L
V
R
-
V
--
C
R
A
A
E
D
A
G
A
D
F
V
K
T
S
T
G
F
H
P
S
-
G
G
A
S
V
R
A
V
A
L
M
A
---
E
A
-----
V
G
---
G
-----
R
L
G
V
K
A
S
G
G
I
R
T
A
A
D
A
L
A
M
L
D
A
G
A
T
R
L
G
L
S
G
--------
T
R
A
V
L
D
G
------------
62
Fugue
75.94
31%
-80
- C2 -
1JCL
1
DEOC_ECOLI
A:
[1-252]
HMT
D
L
K
A
S
S
L
R
A
L
K
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
T
A
A
I
C
I
Y
P
R
F
I
P
I
A
R
K
T
L
---
K
E
Q
G
T
PEI
R
I
A
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
F
P
Y
R
A
L
M
A
G
N
E
Q
V
G
F
D
L
V
--
K
A
C
K
E
A
C
A
A
A
N
V
L
L
K
V
I
I
E
T
G
E
L
---
K
D
----
E
A
L
-
I
R
K
A
--
S
E
I
S
I
K
A
G
A
D
F
I
K
T
S
T
G
K
V
-
A
-
V
N
A
T
P
E
S
A
R
I
M
M
---
E
V
-----
I
R
---
D
M
GVEK
T
V
G
F
K
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
A
I
A
D
E
L
F
G
A
D
W
ADARHYRF
G
A
S
S
L
L
A
---
S
L
L
K
A
L
G
H
G
34
PsiBlast_CBE
74.19
35%
-83
- C2 -
1JCL
1
DEOC_ECOLI
B:
[14-226]
-------------
K
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
T
A
A
I
C
I
Y
P
R
F
I
P
I
A
R
K
T
L
KEQ
G
T
P
E
I
---
R
I
A
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
F
P
Y
R
A
L
M
-
A
G
N
E
Q
V
G
F
D
L
VK
A
C
K
E
A
C
A
A
A
N
-
V
L
L
K
V
I
I
E
T
G
E
L
---
K
D
----
E
A
L
-
I
R
K
A
--
S
E
I
S
I
K
A
G
A
D
F
I
K
T
S
T
G
K
V
-
A
-
V
N
A
T
P
E
S
A
R
I
M
M
---
E
V
IRDMG
V
E
---
K
-----
T
V
G
F
K
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
A
I
A
D
E
L
F
G
A
-----------------------------
15
PsiBlast_PDB
74.16
34%
-84
- C2 -
1JCJ
1
DEOC_ECOLI
A:
[14-226]
-------------
K
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
T
A
A
I
C
I
Y
P
R
F
I
P
I
A
R
K
T
L
K
E
Q
G
T
P
E
I
---
R
I
A
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
F
P
Y
R
A
L
M
-
A
G
N
E
Q
V
G
F
D
L
V
K
A
C
K
E
A
C
A
A
A
N
-
V
L
L
K
V
I
I
E
T
G
E
L
---
K
D
----
E
A
L
-
I
R
K
A
--
S
E
I
S
I
K
A
G
A
D
F
I
K
T
S
T
G
K
V
-
A
-
V
N
A
T
P
E
S
A
R
I
M
M
---
E
V
I
R
D
M
G
V
E
---
K
-----
T
V
G
F
L
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
A
I
A
D
E
L
F
G
A
-----------------------------
35
PsiBlast_CBE
74.10
34%
-83
- C2 -
1JCJ
1
DEOC_ECOLI
B:
[14-226]
-------------
K
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
T
A
A
I
C
I
Y
P
R
F
I
P
I
A
R
K
T
L
KEQ
G
T
P
E
I
---
R
I
A
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
F
P
Y
R
A
L
M
-
A
G
N
E
Q
V
G
F
D
L
VK
A
C
K
E
A
C
A
A
A
N
-
V
L
L
K
V
I
I
E
T
G
E
L
---
K
D
----
E
A
L
-
I
R
K
A
--
S
E
I
S
I
K
A
G
A
D
F
I
K
T
S
T
G
K
V
-
A
-
V
N
A
T
P
E
S
A
R
I
M
M
---
E
V
IRDMG
V
E
---
K
-----
T
V
G
F
L
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
A
I
A
D
E
L
F
G
A
-----------------------------
13
PsiBlast_PDB
73.78
35%
-84
- C2 -
1JCL
1
DEOC_ECOLI
A:
[14-226]
-------------
K
L
M
D
L
T
T
L
N
D
D
D
T
D
E
K
V
I
A
L
C
H
Q
A
K
T
P
VG
N
T
A
A
I
C
I
Y
P
R
F
I
P
I
A
R
K
T
L
K
E
Q
G
T
P
E
I
---
R
I
A
T
V
T
N
F
P
H
G
N
D
D
I
D
I
A
L
A
E
T
R
A
A
I
A
Y
G
A
D
E
V
D
V
V
F
P
Y
R
A
L
M
-
A
G
N
E
Q
V
G
F
D
L
V
K
A
C
K
E
A
C
A
A
A
N
-
V
L
L
K
V
I
I
E
T
G
E
L
---
K
D
----
E
A
L
-
I
R
K
A
--
S
E
I
S
I
K
A
G
A
D
F
I
K
T
S
T
G
K
V
-
A
-
V
N
A
T
P
E
S
A
R
I
M
M
---
E
V
I
R
D
M
G
V
E
---
K
-----
T
V
G
F
K
P
A
G
G
V
R
T
A
E
D
A
Q
K
Y
L
A
I
A
D
E
L
F
G
A
-----------------------------