@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0043: (2015-11-27 )
MKTPIISIIMGSKSDWGTMQKTAEVLDNFGIAYEKKVVSAHRAPDLMFKHAEEARGRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKTRALSGLDSLYSIVQMPGGVPVATMAIGEAGATNAALTALRILSIEDQNLADALAHFHEEQGKIAEESSNELI
Atome Classification :
(40 SA)
.........10........20........30........40....---....50........60........70........80........90........100.......110.......120.......130.......140.......150-.......160.-----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKT
P
I
I
S
I
I
MGSKSDW
G
T
M
Q
K
T
A
E
V
L
D
NFG
I
A
Y
E
K
K
V
V
S
AHRA
P
D
---
L
M
F
K
H
A
E
E
ARGR
G
I
K
I
I
I
AGAGGAAHLPGMVAAKTTL
P
V
IGVP
V
K
T
R
A
L
S
G
L
D
S
L
Y
S
I
V
QMPGGV
P
V
A
T
M
A
IGEAGA
T
N
A
A
L
T
A
L
R
I
L
SIED
Q
N
L
A
D
A
L
A
H
F
H
E
E
QG-KIAEESSNELI-----------
79
HHSearch
98.02
63%
-129
- C4 -
3OOW
7
?
A:
[5-164]
--
S
V
Q
V
G
V
I
M
G
S
K
S
D
W
S
T
M
K
E
C
C
D
I
L
D
N
L
G
I
G
Y
E
C
E
V
V
S
A
H
R
T
P
D
---
K
M
F
D
Y
A
E
T
A
K
E
R
G
L
K
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
K
T
T
L
P
V
L
G
V
P
V
K
S
S
T
L
N
G
Q
D
S
L
L
S
I
V
Q
M
P
A
G
I
P
V
A
T
F
A
I
G
M
A
G
A
K
N
A
A
L
F
A
A
S
I
L
Q
H
T
D
I
N
I
A
K
A
L
A
E
F
R
A
E
Q
T
-
R
F
V
L
E
N
P
D
P
R
------------
21
PsiBlast_CBE
96.70
63%
-129
- C4 -
4AY4
2
?
D:
[21-181]
M
K
S
-
L
V
G
V
I
M
G
S
T
S
D
W
E
T
M
K
Y
A
C
D
I
L
D
E
L
N
I
P
Y
E
K
K
V
V
S
A
H
R
T
P
D
---
Y
M
F
E
Y
A
E
T
A
R
E
R
G
L
K
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
K
T
N
L
P
V
I
G
V
P
V
Q
S
K
A
L
N
G
L
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
A
T
V
A
I
G
K
A
G
S
T
N
A
G
L
L
A
A
Q
I
L
G
S
F
H
D
D
I
H
D
A
L
E
L
R
R
E
A
I
E
-
K
D
V
R
E
G
S
-
E
L
V
-----------
25
PsiBlast_CBE
96.42
63%
-130
- C4 -
4AY3
2
?
C:
[21-178]
M
K
S
-
L
V
G
V
I
M
G
S
T
S
D
W
E
T
M
K
Y
A
C
D
I
L
D
E
L
N
I
P
Y
E
K
K
V
V
S
A
H
R
T
P
D
---
Y
M
F
E
Y
A
E
T
A
R
E
R
G
L
K
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
K
T
N
L
P
V
I
G
V
P
V
Q
S
K
A
L
N
G
L
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
A
T
V
A
I
G
K
A
G
S
T
N
A
G
L
L
A
A
Q
I
L
G
S
F
H
D
D
I
H
D
A
L
E
L
R
R
E
A
I
E
-
K
D
V
R
E
G
S
---------------
3
PsiBlast_PDB
96.30
63%
-130
- C4 -
4AY3
3
?
A:
[22-181]
-
K
S
-
L
V
G
V
I
M
G
S
T
S
D
W
E
T
M
K
Y
A
C
D
I
L
D
E
L
N
I
P
Y
E
K
K
V
V
S
A
H
R
T
P
D
---
Y
M
F
E
Y
A
E
T
A
R
E
R
G
L
K
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
K
T
N
L
P
V
I
G
V
P
V
Q
S
K
A
L
N
G
L
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
A
T
V
A
I
G
K
A
G
S
T
N
A
G
L
L
A
A
Q
I
L
G
S
F
H
D
D
I
H
D
A
L
E
L
R
R
E
A
I
E
-
K
D
V
R
E
G
S
-
E
L
V
-----------
23
PsiBlast_CBE
96.13
63%
-130
- C4 -
4AY4
2
?
B:
[22-180]
-
K
S
-
L
V
G
V
I
M
G
S
T
S
D
W
E
T
M
K
Y
A
C
D
I
L
D
E
L
N
I
P
Y
E
K
K
V
V
S
A
H
R
T
P
D
---
Y
M
F
E
Y
A
E
T
A
R
E
R
G
L
K
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
K
T
N
L
P
V
I
G
V
P
V
Q
S
K
A
L
N
G
L
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
A
T
V
A
I
G
K
A
G
S
T
N
A
G
L
L
A
A
Q
I
L
G
S
F
H
D
D
I
H
D
A
L
E
L
R
R
E
A
I
E
-
K
D
V
R
E
G
S
-
E
L
------------
26
PsiBlast_CBE
95.95
63%
-131
- C4 -
4AY3
1
?
B:
[22-181]
-
K
S
-
L
V
G
V
I
M
G
S
T
S
D
W
E
T
M
K
Y
A
C
D
I
L
D
E
L
N
I
P
Y
E
K
K
V
V
S
A
H
R
T
P
D
---
Y
M
F
E
Y
A
E
T
A
R
E
R
G
L
K
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
K
T
N
L
P
V
I
G
V
P
V
Q
S
K
A
L
N
G
L
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
A
T
V
A
I
G
K
A
G
S
T
N
A
G
L
L
A
A
Q
I
L
G
S
F
H
D
D
I
H
D
A
L
E
L
R
R
E
A
I
E
-
K
D
V
R
E
G
S
-
E
L
V
-----------
2
PsiBlast_PDB
95.56
63%
-131
- C4 -
4B4K
-
?
A:
[2-157]
-
K
S
-
L
V
G
V
I
M
G
S
T
S
D
W
E
T
M
K
Y
A
C
D
I
L
D
E
L
N
I
P
Y
E
K
K
V
V
S
A
H
R
T
P
D
---
Y
M
F
E
Y
A
E
T
A
R
E
R
G
L
K
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
K
T
N
L
P
V
I
G
V
P
V
Q
S
K
A
L
N
G
L
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
A
T
V
A
I
G
K
A
G
S
T
N
A
G
L
L
A
A
Q
I
L
G
S
F
H
D
D
I
H
D
A
L
E
L
R
R
E
A
I
E
-
K
D
V
R
E
G
----------------
5
PsiBlast_PDB
95.42
61%
-129
- C4 -
3OOW
7
?
A:
[8-162]
-----
V
G
V
I
M
G
S
K
S
D
W
S
T
M
K
E
C
C
D
I
L
D
N
L
G
I
G
Y
E
C
E
V
V
S
A
H
R
T
P
D
---
K
M
F
D
Y
A
E
T
A
K
E
R
G
L
K
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
K
T
T
L
P
V
L
G
V
P
V
K
S
S
T
L
N
G
Q
D
S
L
L
S
I
V
Q
M
P
A
G
I
P
V
A
T
F
A
I
G
M
A
G
A
K
N
A
A
L
F
A
A
S
I
L
Q
H
T
D
I
N
I
A
K
A
L
A
E
F
R
A
E
Q
T
-
R
F
V
L
E
N
P
D
P
R
------------
1
PsiBlast_PDB
94.73
63%
-131
- C4 -
1XMP
-
?
A:
[2-156]
-
K
S
-
L
V
G
V
I
M
G
S
T
S
D
W
E
T
M
K
Y
A
C
D
I
L
D
E
L
N
I
P
Y
E
K
K
V
V
S
A
H
R
T
P
D
---
Y
M
F
E
Y
A
E
T
A
R
E
R
G
L
K
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
K
T
N
L
P
V
I
G
V
P
V
Q
S
K
A
L
N
G
L
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
A
T
V
A
I
G
K
A
G
S
T
N
A
G
L
L
A
A
Q
I
L
G
S
F
H
D
D
I
H
D
A
L
E
L
R
R
E
A
I
E
-
K
D
V
R
E
-----------------
24
PsiBlast_CBE
94.70
63%
-127
- C4 -
4AY3
2
?
D:
[22-177]
-
K
S
-
L
V
G
V
I
M
G
S
T
S
D
W
E
T
M
K
Y
A
C
D
I
L
D
E
L
N
I
P
Y
E
K
K
V
V
S
A
H
R
T
P
D
---
Y
M
F
E
Y
A
E
T
A
R
E
R
G
L
K
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
K
T
N
L
P
V
I
G
V
P
V
Q
S
K
A
L
N
G
L
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
A
T
V
A
I
G
K
A
G
S
T
N
A
G
L
L
A
A
Q
I
L
G
S
F
H
D
D
I
H
D
A
L
E
L
R
R
E
A
I
E
-
K
D
V
R
E
G
----------------
22
PsiBlast_CBE
94.52
63%
-128
- C4 -
4AY4
2
?
C:
[22-177]
-
K
S
-
L
V
G
V
I
M
G
S
T
S
D
W
E
T
M
K
Y
A
C
D
I
L
D
E
L
N
I
P
Y
E
K
K
V
V
S
A
H
R
T
P
D
---
Y
M
F
E
Y
A
E
T
A
R
E
R
G
L
K
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
K
T
N
L
P
V
I
G
V
P
V
Q
S
K
A
L
N
G
L
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
A
T
V
A
I
G
K
A
G
S
T
N
A
G
L
L
A
A
Q
I
L
G
S
F
H
D
D
I
H
D
A
L
E
L
R
R
E
A
I
E
-
K
D
V
R
E
G
----------------
4
PsiBlast_PDB
93.87
63%
-127
- C4 -
4AY4
2
?
A:
[22-177]
-
K
S
-
L
V
G
V
I
M
G
S
T
S
D
W
E
T
M
K
Y
A
C
D
I
L
D
E
L
N
I
P
Y
E
K
K
V
V
S
A
H
R
T
P
D
---
Y
M
F
E
Y
A
E
T
A
R
E
R
G
L
K
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
K
T
N
L
P
V
I
G
V
P
V
Q
S
K
A
L
N
G
L
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
A
T
V
A
I
G
K
A
G
S
T
N
A
G
L
L
A
A
Q
I
L
G
S
F
H
D
D
I
H
D
A
L
E
L
R
R
E
A
I
E
-
K
D
V
R
E
G
----------------
6
PsiBlast_PDB
93.86
61%
-126
- C4 -
3OPQ
4
?
A:
[5-159]
-----
V
G
V
I
M
G
S
K
S
D
W
S
T
M
K
E
C
C
D
I
L
D
N
L
G
I
G
Y
E
C
E
V
V
S
A
H
R
T
P
D
---
K
M
F
D
Y
A
E
T
A
K
E
R
G
L
K
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
K
T
T
L
P
V
L
G
V
P
V
K
S
S
T
L
N
G
Q
D
S
L
L
S
I
V
Q
M
P
A
G
I
P
V
A
T
F
A
I
G
M
A
G
A
K
N
A
A
L
F
A
A
S
I
L
Q
H
T
D
I
N
I
A
K
A
L
A
E
F
R
A
E
Q
T
-
R
F
V
L
E
N
P
D
P
R
------------
8
PsiBlast_PDB
93.58
60%
-130
- C4 -
4GRD
-
?
A:
[14-166]
---
P
L
V
G
V
L
M
G
S
S
S
D
W
D
V
M
K
H
A
V
A
I
L
Q
E
F
G
V
P
Y
E
A
K
V
V
S
A
H
R
M
P
D
---
E
M
F
D
Y
A
E
K
A
R
E
R
G
L
R
A
I
I
A
G
A
G
G
A
A
H
L
P
G
M
L
A
A
K
T
T
V
P
V
L
G
V
P
V
A
S
K
Y
L
K
G
V
D
S
L
H
S
I
V
Q
M
P
K
G
V
P
V
A
T
F
A
I
G
E
A
G
A
A
N
A
A
L
F
A
V
S
I
L
S
G
N
S
V
D
Y
A
N
R
L
A
A
F
R
V
R
Q
N
-
E
A
A
H
A
M
V
L
P
P
L
-----------
81
HHSearch
92.68
58%
-126
- C4 -
3ORS
6
?
A:
[3-162]
--
A
M
K
V
A
V
I
M
G
S
S
S
D
W
K
I
M
Q
E
S
C
N
M
L
D
Y
F
E
I
P
Y
E
K
Q
V
V
S
A
H
R
T
P
K
---
M
M
V
Q
F
A
S
E
A
R
E
R
G
I
N
I
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
S
L
T
T
L
P
V
I
G
V
P
I
E
T
K
S
L
K
G
I
D
S
L
L
S
I
V
Q
M
P
G
G
I
P
V
A
T
T
A
I
G
A
A
G
A
K
N
A
G
I
L
A
A
R
M
L
S
I
Q
N
P
S
L
V
E
K
L
N
Q
Y
E
S
S
L
I
-
Q
K
V
E
D
M
Q
N
E
L
Q
-----------
31
PsiBlast_CBE
92.49
59%
-129
- C4 -
3ORS
6
?
D:
[6-162]
-----
V
A
V
I
M
G
S
S
S
D
W
K
I
M
Q
E
S
C
N
M
L
D
Y
F
E
I
P
Y
E
K
Q
V
V
S
A
H
R
T
P
K
---
M
M
V
Q
F
A
S
E
A
R
E
R
G
I
N
I
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
S
L
T
T
L
P
V
I
G
V
P
I
E
T
K
S
L
K
G
I
D
S
L
L
S
I
V
Q
M
P
G
G
I
P
V
A
T
T
A
I
G
A
A
G
A
K
N
A
G
I
L
A
A
R
M
L
S
I
Q
N
P
S
L
V
E
K
L
N
Q
Y
E
S
S
L
I
-
Q
K
V
E
D
M
Q
N
E
L
Q
-----------
29
PsiBlast_CBE
92.38
59%
-128
- C4 -
3ORS
4
?
F:
[6-162]
-----
V
A
V
I
M
G
S
S
S
D
W
K
I
M
Q
E
S
C
N
M
L
D
Y
F
E
I
P
Y
E
K
Q
V
V
S
A
H
R
T
P
K
---
M
M
V
Q
F
A
S
E
A
R
E
R
G
I
N
I
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
S
L
T
T
L
P
V
I
G
V
P
I
E
T
K
S
L
K
G
I
D
S
L
L
S
I
V
Q
M
P
G
G
I
P
V
A
T
T
A
I
G
A
A
G
A
K
N
A
G
I
L
A
A
R
M
L
S
I
Q
N
P
S
L
V
E
K
L
N
Q
Y
E
S
S
L
I
-
Q
K
V
E
D
M
Q
N
E
L
Q
-----------
62
Fugue
92.37
56%
-133
- C4 -
1O4V
2
PURE_THEMA
A:
[14-182]
---
P
R
V
G
I
I
M
G
S
D
S
D
L
P
V
M
K
Q
A
A
E
I
L
E
E
F
G
I
D
Y
E
I
T
I
V
S
A
H
R
T
P
D
---
R
M
F
E
Y
A
K
N
A
E
E
R
G
I
E
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
S
I
T
H
L
P
V
I
G
V
P
V
K
T
S
T
L
N
G
L
D
S
L
F
S
I
V
Q
M
P
G
G
V
P
V
A
T
V
A
I
N
--
N
A
K
N
A
G
I
L
A
A
S
I
L
G
I
K
Y
P
E
I
A
R
K
V
K
E
Y
K
E
R
M
K
-
R
E
V
L
E
K
A
Q
R
L
E
Q
IG
Y
K
E
Y
L
N
Q
K
9
PsiBlast_PDB
92.06
59%
-128
- C4 -
3ORS
6
?
A:
[6-162]
-----
V
A
V
I
M
G
S
S
S
D
W
K
I
M
Q
E
S
C
N
M
L
D
Y
F
E
I
P
Y
E
K
Q
V
V
S
A
H
R
T
P
K
---
M
M
V
Q
F
A
S
E
A
R
E
R
G
I
N
I
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
S
L
T
T
L
P
V
I
G
V
P
I
E
T
K
S
L
K
G
I
D
S
L
L
S
I
V
Q
M
P
G
G
I
P
V
A
T
T
A
I
G
A
A
G
A
K
N
A
G
I
L
A
A
R
M
L
S
I
Q
N
P
S
L
V
E
K
L
N
Q
Y
E
S
S
L
I
-
Q
K
V
E
D
M
Q
N
E
L
Q
-----------
28
PsiBlast_CBE
91.82
59%
-131
- C4 -
3ORS
5
?
G:
[6-162]
-----
V
A
V
I
M
G
S
S
S
D
W
K
I
M
Q
E
S
C
N
M
L
D
Y
F
E
I
P
Y
E
K
Q
V
V
S
A
H
R
T
P
K
---
M
M
V
Q
F
A
S
E
A
R
E
R
G
I
N
I
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
S
L
T
T
L
P
V
I
G
V
P
I
E
T
K
S
L
K
G
I
D
S
L
L
S
I
V
Q
M
P
G
G
I
P
V
A
T
T
A
I
G
A
A
G
A
K
N
A
G
I
L
A
A
R
M
L
S
I
Q
N
P
S
L
V
E
K
L
N
Q
Y
E
S
S
L
I
-
Q
K
V
E
D
M
Q
N
E
L
Q
-----------
34
PsiBlast_CBE
91.40
52%
-132
- C4 -
3LP6
5
PURE_MYCTU
D:
[6-164]
-
E
R
P
R
V
G
V
I
M
G
S
D
S
D
W
P
V
M
A
D
A
A
A
A
L
A
E
F
D
I
P
A
E
V
R
V
V
S
A
H
R
T
P
E
---
A
M
F
S
Y
A
R
G
A
A
A
R
G
L
E
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
A
T
P
L
P
V
I
G
V
P
V
P
L
G
R
L
D
G
L
D
S
L
L
S
I
V
Q
M
P
A
G
V
P
V
A
T
V
S
I
G
--
G
A
G
N
A
G
L
L
A
V
R
M
L
G
A
A
N
P
Q
L
R
A
R
I
V
A
F
Q
D
R
L
A
-
D
V
V
A
A
K
D
A
E
L
Q
-----------
35
PsiBlast_CBE
90.70
52%
-132
- C4 -
3LP6
7
PURE_MYCTU
C:
[6-164]
-
E
R
P
R
V
G
V
I
M
G
S
D
S
D
W
P
V
M
A
D
A
A
A
A
L
A
E
F
D
I
P
A
E
V
R
V
V
S
A
H
R
T
P
E
---
A
M
F
S
Y
A
R
G
A
A
A
R
G
L
E
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
A
T
P
L
P
V
I
G
V
P
V
P
L
G
R
L
D
G
L
D
S
L
L
S
I
V
Q
M
P
A
G
V
P
V
A
T
V
S
I
G
--
G
A
G
N
A
G
L
L
A
V
R
M
L
G
A
A
N
P
Q
L
R
A
R
I
V
A
F
Q
D
R
L
A
-
D
V
V
A
A
K
D
A
E
L
Q
-----------
36
PsiBlast_CBE
89.75
52%
-131
- C4 -
3LP6
8
PURE_MYCTU
B:
[7-164]
--
R
P
R
V
G
V
I
M
G
S
D
S
D
W
P
V
M
A
D
A
A
A
A
L
A
E
F
D
I
P
A
E
V
R
V
V
S
A
H
R
T
P
E
---
A
M
F
S
Y
A
R
G
A
A
A
R
G
L
E
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
A
T
P
L
P
V
I
G
V
P
V
P
L
G
R
L
D
G
L
D
S
L
L
S
I
V
Q
M
P
A
G
V
P
V
A
T
V
S
I
G
--
G
A
G
N
A
G
L
L
A
V
R
M
L
G
A
A
N
P
Q
L
R
A
R
I
V
A
F
Q
D
R
L
A
-
D
V
V
A
A
K
D
A
E
L
Q
-----------
10
PsiBlast_PDB
89.60
52%
-130
- C4 -
3LP6
6
PURE_MYCTU
A:
[6-164]
-
E
R
P
R
V
G
V
I
M
G
S
D
S
D
W
P
V
M
A
D
A
A
A
A
L
A
E
F
D
I
P
A
E
V
R
V
V
S
A
H
R
T
P
E
---
A
M
F
S
Y
A
R
G
A
A
A
R
G
L
E
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
A
T
P
L
P
V
I
G
V
P
V
P
L
G
R
L
D
G
L
D
S
L
L
S
I
V
Q
M
P
A
G
V
P
V
A
T
V
S
I
G
--
G
A
G
N
A
G
L
L
A
V
R
M
L
G
A
A
N
P
Q
L
R
A
R
I
V
A
F
Q
D
R
L
A
-
D
V
V
A
A
K
D
A
E
L
Q
-----------
78
HHSearch
89.30
53%
-127
- C4 -
3LP6
6
PURE_MYCTU
A:
[6-164]
-
E
R
P
R
V
G
V
I
M
G
S
D
S
D
W
P
V
M
A
D
A
A
A
A
L
A
E
F
D
I
P
A
E
V
R
V
V
S
A
H
R
T
P
E
---
A
M
F
S
Y
A
R
G
A
A
A
R
G
L
E
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
V
A
A
A
T
P
L
P
V
I
G
V
P
V
P
L
G
R
L
D
G
L
D
S
L
L
S
I
V
Q
M
P
A
G
V
P
V
A
T
V
S
I
G
G
A
--
G
N
A
G
L
L
A
V
R
M
L
G
A
A
N
P
Q
L
R
A
R
I
V
A
F
Q
D
R
L
A
-
D
V
V
A
A
K
D
A
E
L
Q
-----------
74
HHSearch
88.94
53%
-128
* C4 *
1U11
1
?
A:
[20-178]
-
S
A
P
V
V
G
I
I
M
G
S
Q
S
D
W
E
T
M
R
H
A
D
A
L
L
T
E
L
E
I
P
H
E
T
L
I
V
S
A
H
R
T
P
D
---
R
L
A
D
Y
A
R
T
A
A
E
R
G
L
N
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
C
A
A
W
T
R
L
P
V
L
G
V
P
V
E
S
R
A
L
K
G
M
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
G
T
L
A
I
G
A
S
G
A
K
N
A
A
L
L
A
A
S
I
L
A
L
Y
N
P
A
L
A
A
R
L
E
T
W
R
A
L
Q
T
-
A
S
V
P
N
S
P
I
--------------
49
PsiBlast_CBE
77.83
34%
-124
- C4 -
3RGG
1
?
C:
[3-156]
---
P
L
V
I
I
L
M
G
S
S
S
D
M
G
H
A
E
K
I
A
S
E
L
K
T
F
G
I
E
Y
A
I
R
I
G
S
A
H
K
T
A
E
HVV
S
M
L
K
E
Y
E
A
L
D
R
P
K
L
Y
I
T
I
A
G
R
S
N
A
--
L
S
G
F
V
D
G
F
V
K
G
A
T
I
A
C
P
P
P
S
D
S
F
A
G
A
D
-
I
Y
S
S
L
R
M
P
S
G
I
S
P
A
L
V
----
L
E
P
K
N
A
A
L
L
A
A
R
I
F
S
L
Y
D
K
E
I
A
D
S
V
K
S
Y
M
E
S
N
A
Q
K
I
I
E
D
D
S
K
--------------
39
PsiBlast_CBE
76.94
60%
-114
- C4 -
2FWP
1
?
B:
[23-143]
---
P
V
V
G
I
I
M
G
S
Q
S
D
W
E
T
M
R
H
A
D
A
L
L
T
E
L
E
I
P
H
E
T
L
I
V
S
A
N
R
T
P
D
---
R
L
A
D
Y
A
R
T
A
A
E
R
G
L
N
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
C
A
A
W
T
R
L
P
V
L
G
V
P
V
E
S
R
A
L
K
G
M
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
G
T
L
A
I
G
A
S
G
A
K
N
A
A
L
L
A
A
S
I
L
A
L
Y
N
P
A
L
A
A
R
L
E
T
W
R
A
L
Q
T
-
A
S
V
P
N
S
P
I
T
E
------------
51
PsiBlast_CBE
76.77
34%
-121
- C4 -
3RGG
1
?
A:
[3-156]
---
P
L
V
I
I
L
M
G
S
S
S
D
M
G
H
A
E
K
I
A
S
E
L
K
T
F
G
I
E
Y
A
I
R
I
G
S
A
H
K
T
A
E
H
V
V
S
M
L
K
E
Y
E
A
L
D
R
P
K
L
Y
I
T
I
A
G
R
S
N
A
--
L
S
G
F
V
D
G
F
V
K
G
A
T
I
A
C
P
P
P
S
D
S
F
A
G
A
D
-
I
Y
S
S
L
R
M
P
S
G
I
S
P
A
L
V
----
L
E
P
K
N
A
A
L
L
A
A
R
I
F
S
L
Y
D
K
E
I
A
D
S
V
K
S
Y
M
E
S
N
A
Q
K
I
I
E
D
D
S
K
L
-------------
50
PsiBlast_CBE
76.70
34%
-126
- C4 -
3RGG
1
?
B:
[3-156]
---
P
L
V
I
I
L
M
G
S
S
S
D
M
G
H
A
E
K
I
A
S
E
L
K
T
F
G
I
E
Y
A
I
R
I
G
S
A
H
K
T
A
E
HVV
S
M
L
K
E
Y
E
A
L
D
R
P
K
L
Y
I
T
I
A
G
R
S
N
A
--
L
S
G
F
V
D
G
F
V
K
G
A
T
I
A
C
P
P
P
S
D
S
F
A
G
A
D
-
I
Y
S
S
L
R
M
P
S
G
I
S
P
A
L
V
----
L
E
P
K
N
A
A
L
L
A
A
R
I
F
S
L
Y
D
K
E
I
A
D
S
V
K
S
Y
M
E
S
N
A
Q
K
I
I
E
D
D
S
K
L
-------------
13
PsiBlast_PDB
76.55
61%
-117
- C4 -
2FWJ
1
?
A:
[23-143]
---
P
V
V
G
I
I
M
G
S
Q
S
D
W
E
T
M
R
H
A
D
A
L
L
T
E
L
E
I
P
H
E
T
L
I
V
S
A
H
R
T
P
D
---
R
L
A
D
Y
A
R
T
A
A
E
R
G
L
N
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
C
A
A
W
T
R
L
P
V
L
G
V
P
V
E
S
R
A
L
K
G
M
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
G
T
L
A
I
G
A
S
G
A
K
N
A
A
L
L
A
A
S
I
L
A
L
Y
N
P
A
L
A
A
R
L
E
T
W
R
A
L
Q
T
-
A
S
V
P
N
S
P
I
--------------
37
PsiBlast_CBE
76.06
61%
-117
- C4 -
1U11
1
?
B:
[22-142]
---
P
V
V
G
I
I
M
G
S
Q
S
D
W
E
T
M
R
H
A
D
A
L
L
T
E
L
E
I
P
H
E
T
L
I
V
S
A
H
R
T
P
D
---
R
L
A
D
Y
A
R
T
A
A
E
R
G
L
N
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
C
A
A
W
T
R
L
P
V
L
G
V
P
V
E
S
R
A
L
K
G
M
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
G
T
L
A
I
G
A
S
G
A
K
N
A
A
L
L
A
A
S
I
L
A
L
Y
N
P
A
L
A
A
R
L
E
T
W
R
A
L
Q
T
-
A
S
V
P
N
S
P
I
T
E
------------
38
PsiBlast_CBE
76.02
61%
-115
- C4 -
2FW1
1
?
B:
[23-143]
---
P
V
V
G
I
I
M
G
S
Q
S
D
W
E
T
M
R
H
A
D
A
L
L
T
E
L
E
I
P
H
E
T
L
I
V
S
A
H
R
T
P
D
---
R
L
A
D
Y
A
R
T
A
A
E
R
G
L
N
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
C
A
A
W
T
R
L
P
V
L
G
V
P
V
E
S
R
A
L
K
G
M
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
G
T
L
A
I
G
A
S
G
A
K
N
A
A
L
L
A
A
S
I
L
A
L
Y
N
P
A
L
A
A
R
L
E
T
W
R
A
L
Q
T
-
A
S
V
P
N
S
P
I
T
E
------------
17
PsiBlast_PDB
75.45
60%
-116
- C4 -
2FWI
1
?
A:
[23-143]
---
P
V
V
G
I
I
M
G
S
Q
S
D
W
E
T
M
R
H
A
D
A
L
L
T
E
L
E
I
P
H
E
T
L
I
V
S
A
D
R
T
P
D
---
R
L
A
D
Y
A
R
T
A
A
E
R
G
L
N
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
C
A
A
W
T
R
L
P
V
L
G
V
P
V
E
S
R
A
L
K
G
M
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
G
T
L
A
I
G
A
S
G
A
K
N
A
A
L
L
A
A
S
I
L
A
L
Y
N
P
A
L
A
A
R
L
E
T
W
R
A
L
Q
T
-
A
S
V
P
N
S
P
I
--------------
41
PsiBlast_CBE
75.34
60%
-130
- C4 -
2NSL
1
PURE_ECOLI
A:
[10-119]
-----
V
A
I
V
M
G
S
K
S
D
W
A
T
M
Q
F
A
A
E
I
F
E
I
L
N
V
P
H
H
V
E
V
V
S
A
N
R
T
P
D
---
K
L
F
S
F
A
E
S
A
E
E
N
G
Y
Q
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
I
A
A
K
T
L
V
P
V
L
G
V
P
V
Q
S
A
A
L
S
G
V
D
S
L
Y
S
I
V
Q
M
P
R
G
I
P
V
G
T
L
A
I
G
K
A
G
A
A
N
A
A
L
L
A
A
Q
I
L
A
T
H
D
K
E
L
H
Q
R
L
N
D
W
R
K
A
Q
T
-
D
E
V
L
E
N
P
D
P
R
G
-----------
11
PsiBlast_PDB
75.33
61%
-117
- C4 -
1U11
1
?
A:
[22-142]
---
P
V
V
G
I
I
M
G
S
Q
S
D
W
E
T
M
R
H
A
D
A
L
L
T
E
L
E
I
P
H
E
T
L
I
V
S
A
H
R
T
P
D
---
R
L
A
D
Y
A
R
T
A
A
E
R
G
L
N
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
C
A
A
W
T
R
L
P
V
L
G
V
P
V
E
S
R
A
L
K
G
M
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
G
T
L
A
I
G
A
S
G
A
K
N
A
A
L
L
A
A
S
I
L
A
L
Y
N
P
A
L
A
A
R
L
E
T
W
R
A
L
Q
T
-
A
S
V
P
N
S
P
I
--------------
42
PsiBlast_CBE
75.22
60%
-128
- C4 -
2NSJ
1
PURE_ECOLI
A:
[10-119]
-----
V
A
I
V
M
G
S
K
S
D
W
A
T
M
Q
F
A
A
E
I
F
E
I
L
N
V
P
H
H
V
E
V
V
S
A
Q
R
T
P
D
---
K
L
F
S
F
A
E
S
A
E
E
N
G
Y
Q
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
I
A
A
K
T
L
V
P
V
L
G
V
P
V
Q
S
A
A
L
S
G
V
D
S
L
Y
S
I
V
Q
M
P
R
G
I
P
V
G
T
L
A
I
G
K
A
G
A
A
N
A
A
L
L
A
A
Q
I
L
A
T
H
D
K
E
L
H
Q
R
L
N
D
W
R
K
A
Q
T
-
D
E
V
L
E
N
P
D
P
R
G
-----------
12
PsiBlast_PDB
75.02
61%
-116
- C4 -
2FW1
1
?
A:
[23-143]
---
P
V
V
G
I
I
M
G
S
Q
S
D
W
E
T
M
R
H
A
D
A
L
L
T
E
L
E
I
P
H
E
T
L
I
V
S
A
H
R
T
P
D
---
R
L
A
D
Y
A
R
T
A
A
E
R
G
L
N
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
C
A
A
W
T
R
L
P
V
L
G
V
P
V
E
S
R
A
L
K
G
M
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
G
T
L
A
I
G
A
S
G
A
K
N
A
A
L
L
A
A
S
I
L
A
L
Y
N
P
A
L
A
A
R
L
E
T
W
R
A
L
Q
T
-
A
S
V
P
N
S
P
I
--------------
43
PsiBlast_CBE
74.93
60%
-125
- C4 -
2NSH
1
PURE_ECOLI
A:
[10-119]
-----
V
A
I
V
M
G
S
K
S
D
W
A
T
M
Q
F
A
A
E
I
F
E
I
L
N
V
P
H
H
V
E
V
V
S
A
Q
R
T
P
D
---
K
L
F
S
F
A
E
S
A
E
E
N
G
Y
Q
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
I
A
A
K
T
L
V
P
V
L
G
V
P
V
Q
S
A
A
L
S
G
V
D
S
L
Y
S
I
V
Q
M
P
R
G
I
P
V
G
T
L
A
I
G
K
A
G
A
A
N
A
A
L
L
A
A
Q
I
L
A
T
H
D
K
E
L
H
Q
R
L
N
D
W
R
K
A
Q
T
-
D
E
V
L
E
N
P
D
P
R
G
-----------
40
PsiBlast_CBE
73.96
60%
-113
- C4 -
2FW6
1
?
B:
[23-143]
---
P
V
V
G
I
I
M
G
S
Q
S
D
W
E
T
M
R
H
A
D
A
L
L
T
E
L
E
I
P
H
E
T
L
I
V
S
A
N
R
T
P
D
---
R
L
A
D
Y
A
R
T
A
A
E
R
G
L
N
V
I
I
A
G
A
G
G
A
A
H
L
P
G
M
C
A
A
W
T
R
L
P
V
L
G
V
P
V
E
S
R
A
L
K
G
M
D
S
L
L
S
I
V
Q
M
P
G
G
V
P
V
G
T
L
A
I
G
A
S
G
A
K
N
A
A
L
L
A
A
S
I
L
A
L
Y
N
P
A
L
A
A
R
L
E
T
W
R
A
L
Q
T
-
A
S
V
P
N
S
P
I
T
-------------