@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0097: (2015-11-28 )
MNNTEFYDRLGVSKDASQDEIKKAYRRMSKKYHPDINKETGAEEKYKEVQEAYETLSDTQKRAAYDQYGAAGANGGFGGFDGGGFGGFDGGGFGGFEDIFSSFFGGGGMRNPNAPRQGDDLQYRVNLSFEEAIFGAEKEVSYNRESSCHTCSGSGAKPGTSPVTCQKCHGSGVINVDTQTPLGTMRRQVTCDVCQGSGQEIKEKCPTCHGTGHEKKTHKVSVKIPAGVETGQQIRLTGQGEAGFNGGPYGDLFVIINVLPSQQFERNGSTIYYTLKISFVQAALGDTIDIPTVHGAVEMSIPAGTQTGKTFRLRGKGAPKLRGGGQGDQHVTVNIVTPTKLNDAQKEALHAFAEASGDKMVHPKKKGFFDKVKDALDVD
Atome Classification :
(20 SA)
.........10........20........30.......-.-40........50........60........70-.........80........90........100.......110.......120.......130.......140.-......150.......160.......170.......180.......190--........200-..----......210.-.....---.220.......230.......240.......250.......260.......270.......280.......290...-.-...300..--.....310--.......320.-...-...330.......340.......350.........360.......370.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNN
T
E
F
Y
D
RLGVSKDA
S
Q
D
E
I
K
K
A
Y
R
R
M
S
K
KYHPDINK-E-TG
A
E
E
K
Y
K
E
V
Q
E
A
Y
E
T
L
S
D
T
Q
K
R
A
AYDQYGA--AGANGGFGGFDGGGFGGFDGGGFG
G
F
E
D
I
F
S
S
F
FGGGGMRNPNAPRQGD
D
L
Q
Y
R
V
NL
S
F
E
E
A
IFGAEKEVSYN-RESSCHTCSGSGAKPGTSP
V
T
C
QKCHGS
G
V
I
N
VDTQT
P
L
G
T
M
R
R
Q
V
T
C
---
D
V
CQGS
G
Q
E
I
--
K
E
----KCPTCHGTGH-E
K
K
T
H
---
K
V
S
V
K
IPAGVETG
Q
Q
I
R
L
T
GQGEAGFNGGPYG
D
L
F
V
I
I
NVLP
S
Q
Q
FERNG
S
T
I
Y
Y
T
L
K
I
S
F
V
Q
A
A
LGDTIDIPTVH
G
-
A
-
V
E
M
SIPAG--TQTG
K
T
F
R
--
L
RGKGAPKLRG-GGQ-GD
Q
H
V
T
V
N
I
VTPTKLN
D
A
Q
K
E
A
L
H
--
A
F
A
EASGDKMVHPKKKG
F
F
D
K
V
K
D
A
LDVD
59
HHSearch
78.07
28%
-68
- C3 -
1NLT
3
MAS5_YEAST
A:
[8-235]
----------------------------------------------------------------------------------------------------------------------
P
Q
R
G
K
D
I
K
H
E
I
S
A
S
L
E
E
L
Y
K
G
R
T
A
K
L
A
L
N
-
K
Q
I
L
C
K
E
C
E
G
R
G
G
K
K
G
-
A
V
K
K
C
T
S
C
N
G
Q
G
I
K
F
V
T
R
Q
M
G
P
M
I
Q
R
F
Q
T
E
C
---
D
V
C
H
G
T
G
D
I
I
D
P
K
D
----
R
C
K
S
C
N
G
K
K
V
-
E
N
E
R
K
---
I
L
E
V
H
V
E
P
G
M
K
D
G
Q
R
I
V
F
K
G
E
A
D
Q
A
-
P
D
V
I
P
G
D
V
V
F
I
V
S
E
R
P
H
K
S
F
K
R
D
G
D
D
L
V
Y
E
A
E
I
D
L
L
T
A
I
A
G
G
E
F
A
L
E
H
V
S
G
-
D
W
L
K
V
G
I
V
P
G
EV
I
A
P
G
M
R
K
V
--
I
E
G
K
G
M
P
I
P
K
Y
-
G
G
Y
-
G
N
L
I
I
K
F
T
I
K
D
P
E
------------------------------------------
2
PsiBlast_PDB
76.40
28%
-66
- C3 -
1NLT
3
MAS5_YEAST
A:
[8-234]
----------------------------------------------------------------------------------------------------------------------
P
Q
R
G
K
D
I
K
H
E
I
S
A
S
L
E
E
L
Y
K
G
R
T
A
K
L
A
L
N
-
K
Q
I
L
C
K
E
C
E
G
R
G
G
K
K
G
A
V
K
-
K
C
T
S
C
N
G
Q
G
I
K
F
V
T
R
Q
M
G
P
M
I
Q
R
F
Q
T
E
C
---
D
V
C
H
G
T
G
D
I
I
D
P
K
D
----
R
C
K
S
C
N
G
K
K
V
-
E
N
E
R
K
---
I
L
E
V
H
V
E
P
G
M
K
D
G
Q
R
I
V
F
K
G
E
A
D
Q
A
P
D
V
I
P
-
G
D
V
V
F
I
V
S
E
R
P
H
K
S
F
K
R
D
G
D
D
L
V
Y
E
A
E
I
D
L
L
T
A
I
A
G
G
E
F
A
L
E
H
V
S
G
D
W
-
L
K
V
G
I
V
P
G
--
E
V
I
A
P
G
M
R
K
V
I
E
G
K
G
M
P
I
P
K
Y
-
G
G
Y
-
G
N
L
I
I
K
F
T
I
K
D
P
E
------------------------------------------
3
PsiBlast_PDB
73.31
32%
-49
- C2 -
4J80
-
DNAJ2_THET8
A:
[6-248]
----
D
Y
Y
A
I
L
G
V
P
R
N
A
T
Q
E
E
I
K
R
A
Y
K
R
L
A
R
Q
Y
H
P
D
V
N
K
-
S
-
P
E
A
E
E
K
F
K
E
I
N
E
A
Y
A
V
M
S
D
P
E
K
R
R
I
Y
D
T
Y
G
T
TE
A
P
P
P
P
P
P
G
G
Y
D
---
F
S
G
F
D
V
E
D
F
S
E
F
---
F
Q
E
L
F
G
P
G
L
F
------
G
K
G
R
D
L
R
A
E
L
P
L
T
L
E
E
A
F
H
G
G
E
R
V
V
E
V
A
G
R
R
V
S
V
R
M
P
--
P
G
V
R
E
G
-
S
V
I
R
V
P
G
M
G
G
Q
G
N
P
P
G
D
----
L
L
L
V
V
R
M
L
P
H
---
P
V
F
R
L
E
G
Q
D
L
--
Y
A
T
L
D
V
P
A
P
I
A
V
V
G
G
K
-
V
R
A
M
T
LE
G
P
V
E
V
A
V
P
P
R
T
Q
A
G
R
K
M
R
L
K
G
G
G
F
P
G
P
A
G
--
R
G
D
L
Y
L
E
V
R
I
T
I
P
E
R
L
T
P
E
E
E
A
L
W
K
K
L
A
E
A
Y
Y
A
R
-----------------------------------------------------------------------------------------------------------
82
Fugue
70.22
29%
-76
- C3 -
3LZ8
-
?
A:
[113-302]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
R
G
H
D
L
E
I
E
V
A
V
F
LE
E
T
L
A
E
Q
T
R
T
I
--
S
Y
----
N
L
P
V
Y
N
V
F
G
I
E
S
E
T
P
K
---
T
L
N
V
K
I
P
A
G
V
V
D
G
Q
R
I
R
L
K
G
Q
G
T
---
P
G
G
P
N
G
D
L
W
L
V
I
H
I
A
P
H
P
L
F
D
I
V
G
H
N
L
E
I
V
L
P
L
A
P
W
E
A
A
L
G
A
K
V
T
V
P
T
L
K
E
-
S
-
I
L
L
T
V
P
P
G
--
S
Q
A
G
Q
R
L
R
--
I
K
G
K
G
L
V
--
S
K
-
T
H
T
-
G
D
L
F
A
V
I
K
I
V
M
P
T
K
P
D
E
K
A
R
E
L
W
Q
--
Q
L
A
A
A
E
A
S
F
D
P
R
K
T
W
--------------
58
HHSearch
69.54
37%
-77
- C3 -
3LZ8
-
?
A:
[113-294]
----------------------------------------------------------------------------------------------------------------------
A
A
R
G
H
D
L
E
I
E
V
A
V
F
L
E
E
T
L
A
E
Q
T
R
T
I
S
Y
N
-
L
P
V
Y
N
--
V
F
------------------------------------------------------------------
G
-
I
E
-
S
E
T
P
K
---
T
L
N
V
K
I
P
A
G
V
V
D
G
Q
R
I
R
L
K
G
Q
G
T
P
G
---
G
P
N
G
D
L
W
L
V
I
H
I
A
P
H
P
L
F
D
I
V
G
H
N
L
E
I
V
L
P
L
A
P
W
E
A
A
L
G
A
K
V
T
V
P
T
L
K
E
-
S
-
I
L
L
T
V
P
P
G
--
S
Q
A
G
Q
R
L
R
--
I
K
G
K
G
L
V
S
K
T
---
H
T
-
G
D
L
F
A
V
I
K
I
V
M
P
T
K
P
D
E
K
A
R
E
L
W
Q
--
Q
L
A
A
A
E
A
S
F
D
P
R
K
T
W
--------------
1
PsiBlast_PDB
63.63
32%
-63
- C3 -
3LZ8
-
?
A:
[113-297]
---------------------------------------------------------------------------------------------------------------------
A
A
R
-
G
H
D
L
E
------
I
E
V
A
V
F
L
E
E
T
L
A
E
Q
T
-
R
T
I
S
Y
N
-------------
L
P
V
Y
N
V
F
G
-----
I
E
S
E
T
P
--------------------------------------------
K
T
-----
L
N
V
K
I
P
A
G
V
V
D
G
Q
R
I
R
L
K
G
Q
G
T
P
G
---
G
P
N
G
D
L
W
L
V
I
H
I
A
P
H
P
L
F
D
I
V
G
H
N
L
E
I
V
L
P
L
A
P
W
E
A
A
L
G
A
K
V
T
V
P
T
L
K
E
-
S
-
I
L
L
T
V
P
P
G
--
S
Q
A
G
Q
R
L
R
--
I
K
G
K
G
L
--
V
S
K
-
T
H
T
-
G
D
L
F
A
V
I
K
I
V
M
P
T
K
P
D
E
K
A
R
E
L
W
Q
Q
L
A
A
A
E
A
S
F
D
P
R
K
T
W
----------------
62
HHSearch
61.12
26%
-70
- C3 -
1C3G
-
SIS1_YEAST
A:
[180-349]
--------------------------------------------------------------------------------------------------------------------------
E
T
V
Q
V
N
L
P
V
S
L
E
D
L
F
V
G
K
K
K
S
F
K
I
G
-
R
K
G
P
H
G
--------------------------------------------------------------------------
A
S
E
K
T
---
Q
I
D
I
Q
L
K
P
G
W
K
A
G
T
K
I
T
Y
K
N
Q
G
D
Y
N
P
Q
T
G
R
R
K
T
L
Q
F
V
I
Q
E
K
S
H
P
N
F
K
R
D
G
D
D
L
I
Y
T
L
P
L
S
F
K
E
S
L
L
G
F
S
K
T
I
Q
T
I
D
G
-
R
T
L
P
L
S
R
V
Q
P
--
V
Q
P
S
Q
T
S
T
--
Y
P
G
Q
G
M
P
T
P
K
N
P
S
Q
R
-
G
N
L
I
V
K
Y
K
V
D
Y
P
I
S
L
N
D
A
Q
K
R
A
I
D
-------------------------------
60
HHSearch
58.91
19%
-70
- C3 -
3AGX
-
DNJB1_HUMAN
A:
[165-339]
-----------------------------------------------------------------------------------------------------------------------------
T
H
D
L
R
V
S
L
E
E
I
Y
S
G
C
T
K
K
M
K
I
S
-
H
K
R
L
N
P
D
--------------------------------------------------------------------
G
K
S
I
-
R
N
E
D
K
---
I
L
T
I
E
V
K
K
G
W
K
E
G
T
K
I
T
F
P
K
E
G
D
Q
T
S
-
N
N
I
P
A
D
I
V
F
V
L
K
D
K
P
H
N
I
F
K
R
D
G
S
D
V
I
Y
P
A
R
I
S
L
R
E
A
L
C
G
C
T
V
N
V
P
T
L
D
G
-
R
T
I
P
V
V
F
K
D
V
--
I
R
P
G
M
R
R
K
--
V
P
G
E
G
L
P
L
P
K
T
P
E
K
R
-
G
D
L
I
I
E
F
E
V
I
F
P
E
R
I
P
Q
T
S
R
T
V
L
E
--
Q
V
L
P
I
------------------------
61
HHSearch
57.98
21%
-73
- C3 -
2Q2G
1
?
A:
[4-179]
--------------------------------------------------------------------------------------------------------------------------
R
S
H
E
V
P
L
L
V
T
L
E
E
L
Y
L
G
K
R
K
K
I
K
V
T
-
R
K
R
F
I
E
H
----------------------------------------------------------------------
K
V
-
R
N
E
E
N
---
I
V
E
V
E
I
K
P
G
W
K
D
G
T
K
L
T
Y
S
G
E
G
D
Q
E
S
P
G
T
S
P
G
D
L
V
L
I
I
Q
T
K
T
H
P
R
F
T
R
D
D
C
H
L
I
M
K
V
T
I
P
L
V
R
A
L
T
G
F
T
C
P
V
T
T
L
D
N
-
R
N
L
Q
I
P
I
K
E
I
--
V
N
P
K
T
R
K
I
--
V
P
N
E
G
M
P
I
K
N
Q
P
G
Q
K
-
G
D
L
I
L
E
F
D
I
C
F
P
K
S
L
T
P
E
Q
K
K
L
I
K
--
E
A
L
--------------------------
80
Fugue
56.06
24%
-62
- C3 -
1C3G
-
SIS1_YEAST
A:
[180-349]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
V
Q
V
N
L
P
V
---
S
L
E
D
L
F
V
G
K
K
--
K
S
----
F
K
I
G
R
K
G
P
H
G
-
A
S
E
K
T
---
Q
I
D
I
Q
L
K
P
G
W
K
A
G
T
K
I
T
Y
K
N
Q
G
D
Y
N
P
Q
T
G
R
R
K
T
L
Q
F
V
I
Q
E
K
S
H
P
N
F
K
R
D
G
D
D
L
I
Y
T
L
P
L
S
F
K
E
S
L
L
G
F
S
K
T
I
Q
T
I
D
G
R
T
-
L
P
L
S
R
V
Q
P
--
V
Q
P
S
Q
T
S
T
--
Y
P
G
Q
G
M
P
T
P
K
N
-
P
S
Q
R
G
N
L
I
V
K
Y
K
V
D
Y
P
I
S
L
N
D
A
Q
K
R
A
I
D
-------------------------------
71
HHSearch
50.78
53%
-31
- C2 -
2DN9
-
A:
[5-75]
-
S
S
G
D
Y
Y
Q
I
L
G
V
P
R
N
A
S
Q
K
E
I
K
K
A
Y
Y
Q
L
A
K
K
Y
H
P
D
T
N
K
-
D
D
P
K
A
K
E
K
F
S
Q
L
A
E
A
Y
E
V
L
S
D
E
V
K
R
K
Q
Y
D
A
Y
G
S
--
G
P
S
S
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
49.69
50%
-33
- C2 -
2LO1
-
DNJA1_HUMAN
A:
[3-67]
V
K
E
T
T
Y
Y
D
V
L
G
V
K
P
N
A
T
Q
E
E
L
K
K
A
Y
R
K
L
A
L
K
Y
H
P
D
K
N
P
-
N
-
E
G
--
E
K
F
K
Q
I
S
Q
A
Y
E
V
L
S
D
A
K
K
R
E
L
Y
D
K
G
G
E
--
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
48.89
56%
-60
- C2 -
4WB7
-
DNJB1_HUMAN (first)
A:
[3-67]
----
D
Y
Y
Q
T
L
G
L
A
R
G
A
S
D
E
E
I
K
R
A
Y
R
R
Q
A
L
R
Y
H
P
D
K
N
K
-
E
-
P
G
A
E
E
K
F
K
E
I
A
E
A
Y
D
V
L
S
D
P
R
K
R
E
I
F
D
R
Y
G
E
--
E
V
K
E
F
L
A
K
A
K
E
D
F
L
K
K
W
E
S
P
A
Q
N
T
A
H
L
D
Q
F
E
R
I
K
T
L
G
T
G
S
F
G
R
V
M
L
V
K
H
K
E
T
G
N
H
Y
A
M
K
I
L
D
K
Q
K
V
V
K
L
K
Q
I
E
-
H
T
L
N
E
K
R
I
L
Q
A
V
N
F
P
F
L
V
K
L
E
F
S
F
K
D
N
S
N
L
Y
M
V
M
E
Y
V
P
G
G
E
M
F
S
H
L
R
R
---
I
G
R
F
S
E
P
H
A
R
--
F
Y
----
A
A
Q
I
V
L
T
F
E
Y
-
L
H
S
L
D
---
L
I
Y
R
D
L
K
P
E
N
L
L
I
D
Q
Q
G
Y
I
Q
V
T
D
F
G
F
A
K
R
V
K
G
R
T
W
T
L
C
G
T
P
E
Y
L
A
P
E
I
I
L
S
K
G
Y
N
K
A
V
D
W
W
A
L
G
V
L
I
Y
E
M
A
A
G
Y
P
P
F
-
F
-
A
D
Q
P
I
Q
I
Y
--
E
K
I
V
S
G
K
V
--
R
F
P
S
H
F
S
S
D
L
K
-
D
L
L
-
R
N
L
L
Q
V
D
L
T
K
R
F
G
N
L
K
N
G
V
N
D
I
K
N
--
H
K
W
F
A
T
T
D
W
I
A
I
Y
Q
R
K
V
E
A
P
F
I
P
K
F
K
G
P
G
14
PsiBlast_PDB
48.76
52%
-33
- C2 -
2DN9
-
A:
[8-79]
----
D
Y
Y
Q
I
L
G
V
P
R
N
A
S
Q
K
E
I
K
K
A
Y
Y
Q
L
A
K
K
Y
H
P
D
T
N
K
D
D
-
P
K
A
K
E
K
F
S
Q
L
A
E
A
Y
E
V
L
S
D
E
V
K
R
K
Q
Y
D
A
Y
G
S
--
G
P
S
S
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
48.11
52%
-25
- C2 -
3UCS
-
CBPA_ECOLI
C:
[6-68]
----
D
Y
Y
A
I
M
G
V
K
P
T
D
D
L
K
T
I
K
T
A
Y
R
R
L
A
R
K
Y
H
P
D
V
S
K
-
E
-
P
D
A
E
A
R
F
K
E
V
A
E
A
W
E
V
L
S
D
E
Q
R
R
A
E
Y
D
Q
M
W
Q
--
H
R
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
66
HHSearch
47.82
53%
-36
- C2 -
1HDJ
-
DNJB1_HUMAN
A:
[1-72]
--
G
K
D
Y
Y
Q
T
L
G
L
A
R
G
A
S
D
E
E
I
K
R
A
Y
R
R
Q
A
L
R
Y
H
P
D
K
N
K
-
E
-
P
G
A
E
E
K
F
K
E
I
A
E
A
Y
D
V
L
S
D
P
R
K
R
E
I
F
D
R
Y
G
E
--
E
G
L
K
G
S
G
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
67
HHSearch
47.77
52%
-21
- C2 -
2OCH
-
?
A:
[3-68]
-
K
E
T
G
Y
Y
D
V
L
G
V
K
P
D
A
S
D
N
E
L
K
K
A
Y
R
K
M
A
L
K
F
H
P
D
K
N
P
----
D
G
A
E
Q
F
K
Q
I
S
Q
A
Y
E
V
L
S
D
E
K
K
R
Q
I
Y
D
Q
G
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
47.72
54%
-34
- C2 -
1HDJ
-
DNJB1_HUMAN
A:
[3-73]
----
D
Y
Y
Q
T
L
G
L
A
R
G
A
S
D
E
E
I
K
R
A
Y
R
R
Q
A
L
R
Y
H
P
D
K
N
K
-
E
-
P
G
A
E
E
K
F
K
E
I
A
E
A
Y
D
V
L
S
D
P
R
K
R
E
I
F
D
R
Y
G
E
--
E
G
L
K
G
S
G
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
47.61
53%
-24
- C2 -
2OCH
-
?
A:
[3-66]
-
K
E
T
G
Y
Y
D
V
L
G
V
K
P
D
A
S
D
N
E
L
K
K
A
Y
R
K
M
A
L
K
F
H
P
D
K
N
P
-
D
--
G
A
E
Q
-
F
K
Q
I
S
Q
A
Y
E
V
L
S
D
E
K
K
R
Q
I
Y
D
Q
G
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
47.05
53%
-13
- C2 -
4RWU
-
SIS1_YEAST
A:
[5-75]
V
K
E
T
K
L
Y
D
L
L
G
V
S
P
S
A
N
E
Q
E
L
K
K
G
Y
R
K
A
A
L
K
Y
H
P
D
--
K
-
P
-
T
G
D
T
E
K
F
K
E
I
S
E
A
F
E
I
L
N
D
P
Q
K
R
E
I
Y
D
Q
Y
G
L
--
E
A
A
R
S
G
G
P
S
F
G
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------