@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : gbs0441: (2015-11-30 )
MKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKNELLKLVDETTGIRLHFIRQSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNNKVIPLTKQLINDFEATHASTIAVMEVPHEDVSAYGVIAPQGEGVNGLYSVNTFVEKPSPEEAPSNLAIIGRYLLTPEIFNILETQKPGAGNEIQLTDAIDTLNKTQRVFARKFTGDRYDVGDKFGFMKTSIDYALQHPQVKDDLKKYIIDLGKSLEKTSKK
Atome Classification :
(20 SA)
.........10........20........30....-....40........50........60.........70........80........90-..-.-....-----.100.......110.......120-.....--....130.......140.----......150..-.....-160.......170.......180-.-..-.....190.......-----200.......210.....-..220...-....230.......240-.......-----------.250-........260.......270....----...280.......290.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKV
R
K
A
VIPAAGLGTRFL
P
A
T
K
A
L
A
K
E
M
LPIVDK
P
-
T
I
Q
F
I
V
E
E
A
L
K
SG
I
E
D
I
L
V
V
TGKSK-R
S
I
E
D
HFDSN
F
E
L
E
Y
NLKEK
G
K
N
E
L
L
K
L
V
DE-TT-
G
-
I
R
L
H
-----
F
I
RQSHPR
G
L
G
D
A
V
L
Q
A
K
A
FVG---NE
P
F
V
--
V
M
LGD
D
L
M
D
ITNN
K
V
I
P
L
----
T
K
Q
L
I
N
D
F
E
AT-HA
S
T
I
-
A
V
M
EVPHE
D
V
SAY
G
V
IAPQGE-G-V-N
G
-
L
Y
S
V
N
T
FVEKPSPEE-----APSN
L
A
I
I
G
R
Y
LL
T
P
E
I
F
-
N
I
L
ETQKP-GAGN
E
I
Q
L
T
D
A
I
D
T
L
-
N
-
K
T
Q
R
V
F
A
-----------
R
KF--TGDRYDVGDKFGFM
K
T
S
I
D
Y
ALQHP----
Q
V
K
D
D
L
K
K
Y
I
I
D
L
G
K
S
L
E
K
TSKK
2
PsiBlast_PDB
97.47
46%
-101
- C1 -
3JUK
4
?
A:
[2-268]
--
I
K
K
C
L
F
P
A
A
G
Y
G
T
R
F
L
P
I
T
K
T
I
P
K
E
M
L
P
I
V
D
K
P
-
L
I
Q
Y
A
V
E
E
A
M
E
A
G
C
E
V
M
A
I
V
T
G
R
N
K
-
R
S
L
E
D
Y
F
D
T
S
Y
--------
T
N
K
E
N
A
L
K
S
I
R
N
-
I
I
E
K
-
C
C
F
S
-----
Y
V
R
Q
K
Q
M
K
G
L
G
H
A
I
L
T
G
E
A
L
I
G
---
N
E
P
F
A
--
V
I
L
A
D
D
L
C
I
S
H
D
H
P
S
V
------
L
K
Q
M
T
S
L
Y
Q
K
Y
-
Q
C
S
I
V
-
A
I
E
E
V
A
L
E
E
V
S
K
Y
G
V
I
--
R
G
E
-
W
-
L
E
E
G
-
V
Y
E
I
K
D
M
V
E
K
P
N
Q
E
D
-----
A
P
S
N
L
A
V
I
G
R
Y
I
L
T
P
D
I
F
-
E
I
L
S
E
T
K
P
-
G
K
N
N
E
I
Q
I
T
D
A
L
R
T
Q
-
A
-
K
R
K
R
I
I
A
-----------
Y
Q
F
--
K
G
K
R
Y
D
C
G
S
V
E
G
Y
I
E
A
S
N
A
Y
Y
K
K
R
L
---------------------------
22
PsiBlast_CBE
97.13
46%
-98
- C1 -
3JUK
4
?
C:
[2-268]
--
I
K
K
C
L
F
P
A
A
G
Y
G
T
R
F
L
P
I
T
K
T
I
P
K
E
M
L
P
I
V
D
K
P
-
L
I
Q
Y
A
V
E
E
A
M
E
A
G
C
E
V
M
A
I
V
T
G
R
N
K
-
R
S
L
E
D
Y
F
D
T
S
Y
---------
N
K
E
N
A
L
K
S
I
R
N
-
I
I
E
K
-
C
C
F
S
-----
Y
V
R
Q
K
Q
M
K
G
L
G
H
A
I
L
T
G
E
A
L
I
G
---
N
E
P
F
A
--
V
I
L
A
D
D
L
C
I
S
H
D
H
P
S
V
------
L
K
Q
M
T
S
L
Y
Q
K
Y
-
Q
C
S
I
V
-
A
I
E
E
V
A
L
E
E
V
S
K
Y
G
V
I
--
R
G
E
-
W
-
L
E
E
G
-
V
Y
E
I
K
D
M
V
E
K
P
N
Q
E
D
-----
A
P
S
N
L
A
V
I
G
R
Y
I
L
T
P
D
I
F
-
E
I
L
S
E
T
K
P
-
G
K
N
N
E
I
Q
I
T
D
A
L
R
T
Q
-
A
-
K
R
K
R
I
I
A
-----------
Y
Q
F
--
K
G
K
R
Y
D
C
G
S
V
E
G
Y
I
E
A
S
N
A
Y
Y
K
K
R
L
---------------------------
23
PsiBlast_CBE
96.42
46%
-99
- C1 -
3JUK
4
?
B:
[2-268]
--
I
K
K
C
L
F
P
A
A
G
Y
G
T
R
F
L
P
I
T
K
T
I
P
K
E
M
L
P
I
V
D
K
P
-
L
I
Q
Y
A
V
E
E
A
M
E
A
G
C
E
V
M
A
I
V
T
G
R
N
K
-
R
S
L
E
D
Y
F
D
T
S
Y
---------
N
K
E
N
A
L
K
S
I
R
N
-
I
I
E
K
-
C
C
F
S
-----
Y
V
R
Q
K
Q
M
K
G
L
G
H
A
I
L
T
G
E
A
L
I
G
---
N
E
P
F
A
--
V
I
L
A
D
D
L
C
I
S
H
D
H
P
S
V
------
L
K
Q
M
T
S
L
Y
Q
K
Y
-
Q
C
S
I
V
-
A
I
E
E
V
A
L
E
E
V
S
K
Y
G
V
I
--
R
G
E
-
W
-
L
E
E
G
-
V
Y
E
I
K
D
M
V
E
K
P
N
Q
E
D
-----
A
P
S
N
L
A
V
I
G
R
Y
I
L
T
P
D
I
F
-
E
I
L
S
E
T
K
P
-
G
K
N
N
E
I
Q
I
T
D
A
L
R
T
Q
-
A
-
K
R
K
R
I
I
A
-----------
Y
Q
F
--
K
G
K
R
Y
D
C
G
S
V
E
G
Y
I
E
A
S
N
A
Y
Y
K
K
R
----------------------------
21
PsiBlast_CBE
95.95
46%
-98
- C1 -
3JUK
4
?
D:
[2-268]
--
I
K
K
C
L
F
P
A
A
G
Y
G
T
R
F
L
P
I
T
K
T
I
P
K
E
M
L
P
I
V
D
K
P
-
L
I
Q
Y
A
V
E
E
A
M
E
A
G
C
E
V
M
A
I
V
T
G
R
N
K
-
R
S
L
E
D
Y
F
D
T
S
Y
--------
T
N
K
E
N
A
L
K
S
I
R
N
-
I
I
E
K
-
C
C
F
S
-----
Y
V
R
Q
K
Q
M
K
G
L
G
H
A
I
L
T
G
E
A
L
I
G
---
N
E
P
F
A
--
V
I
L
A
D
D
L
C
I
S
H
D
H
P
S
V
------
L
K
Q
M
T
S
L
Y
Q
K
Y
-
Q
C
S
I
V
-
A
I
E
E
V
A
L
E
E
V
S
K
Y
G
V
I
--
R
G
E
-
W
-
L
E
E
G
-
V
Y
E
I
K
D
M
V
E
K
P
N
Q
E
D
-----
A
P
S
N
L
A
V
I
G
R
Y
I
L
T
P
D
I
F
-
E
I
L
S
E
T
K
P
-
G
K
N
N
E
I
Q
I
T
D
A
L
R
T
Q
-
A
-
K
R
K
R
I
I
A
-----------
Y
Q
F
--
K
G
K
R
Y
D
C
G
S
V
E
G
Y
I
E
A
S
N
A
Y
Y
K
K
R
----------------------------
42
HHSearch
95.35
46%
-98
- C1 -
3JUK
5
?
A:
[1-273]
-
M
I
K
K
C
L
F
P
A
A
G
Y
G
T
R
F
L
P
I
T
K
T
I
P
K
E
M
L
P
I
V
D
K
P
-
L
I
Q
Y
A
V
E
E
A
M
E
A
G
C
E
V
M
A
I
V
T
G
R
N
K
-
R
S
L
E
D
Y
F
D
T
S
Y
--------
T
N
K
E
N
A
L
K
S
I
R
N
I
I
E
-
K
-
C
C
F
S
-----
Y
V
R
Q
K
Q
M
K
G
L
G
H
A
I
L
T
G
E
A
L
I
G
---
N
E
P
F
A
--
V
I
L
A
D
D
L
C
I
S
------
H
D
HPS
V
L
K
Q
M
T
S
L
Y
Q
K
Y
--
Q
C
S
I
V
A
I
E
E
V
A
L
E
E
V
S
K
Y
G
V
I
R
G
E
W
L
---
E
-
E
G
-
V
Y
E
I
K
D
M
V
E
K
P
N
Q
E
D
-----
A
P
S
N
L
A
V
I
G
R
Y
I
L
T
P
D
I
F
-
E
I
L
S
E
T
K
P
-
G
K
N
N
E
I
Q
I
T
D
A
L
R
T
Q
-
A
-
K
R
K
R
I
I
A
-----------
Y
Q
F
--
K
G
K
R
Y
D
C
G
S
V
E
G
Y
I
E
A
S
N
A
Y
Y
K
K
R
L
---------------------------
1
PsiBlast_PDB
94.58
46%
-95
- C1 -
3JUJ
-
?
A:
[2-268]
--
I
K
K
C
L
F
P
A
A
G
Y
G
T
R
F
L
P
I
T
K
T
I
P
K
E
M
L
P
I
V
D
K
P
-
L
I
Q
Y
A
V
E
E
A
M
E
A
G
C
E
V
M
A
I
V
T
G
R
N
K
-
R
S
L
E
D
Y
F
D
T
S
Y
E
I
E
H
Q
I
Q
G
T
N
K
E
N
A
L
K
S
I
R
N
-
I
I
E
K
-
C
C
F
S
-----
Y
V
R
Q
K
Q
M
K
G
L
G
H
A
I
L
T
G
E
A
L
I
G
---
N
E
P
F
A
--
V
I
L
A
D
D
L
C
I
S
H
D
H
P
S
V
------
L
K
Q
M
T
S
L
Y
Q
K
Y
-
Q
C
S
I
V
-
A
I
E
E
V
A
L
E
E
V
S
K
Y
G
V
I
--
R
G
E
-
W
-
L
E
E
G
-
V
Y
E
I
K
D
M
V
E
K
P
N
Q
E
D
-----
A
P
S
N
L
A
V
I
G
R
Y
I
L
T
P
D
I
F
-
E
I
L
S
E
T
K
P
-
G
K
N
N
E
I
Q
I
T
D
A
L
R
T
Q
-
A
-
K
R
K
R
I
I
A
-----------
Y
Q
F
--
K
G
K
R
Y
D
C
G
S
V
E
G
Y
I
E
A
S
N
A
Y
Y
K
K
R
L
---------------------------
28
PsiBlast_CBE
92.98
44%
-90
- C1 -
2UX8
1
?
D:
[14-293]
--
L
R
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
M
P
K
E
M
L
P
V
V
D
R
P
-
L
I
Q
Y
A
V
D
E
A
V
E
A
G
I
E
Q
M
I
F
V
T
G
R
G
K
-
S
A
L
E
D
H
F
D
I
A
Y
E
L
E
A
T
M
A
A
R
G
K
S
-----
L
D
V
-
L
D
-
G
-
T
R
L
K
PGN
I
A
Y
V
R
Q
Q
E
P
M
G
L
G
H
A
V
W
C
A
R
D
I
V
G
---
D
E
P
F
A
--
V
L
L
P
D
D
F
M
F
G
Q
P
G
C
L
--------
K
Q
M
V
D
A
Y
N
K
V
-
G
G
N
L
I
-
C
A
E
E
V
P
D
D
Q
T
H
R
Y
G
I
I
T
P
G
T
Q
D
G
-
V
----
L
T
E
V
K
G
L
V
E
K
P
A
P
G
T
-----
A
P
S
N
L
S
V
I
G
R
Y
I
L
Q
P
E
V
M
-
R
I
L
E
N
Q
G
--------
Q
L
T
D
A
M
Q
R
M
-
I
-
G
D
Q
P
F
H
G
-----------
V
T
F
--
Q
G
T
R
Y
D
C
G
D
K
A
G
F
I
Q
A
N
L
A
V
A
L
S
R
P
----
D
L
E
P
A
V
R
A
F
A
V
K
A
L
G
--------
27
PsiBlast_CBE
91.91
44%
-92
- C1 -
2UX8
1
?
E:
[14-293]
--
L
R
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
M
P
K
E
M
L
P
V
V
D
R
P
-
L
I
Q
Y
A
V
D
E
A
V
E
A
G
I
E
Q
M
I
F
V
T
G
R
G
K
-
S
A
L
E
D
H
F
D
I
A
Y
E
L
E
A
T
M
A
A
R
G
K
S
-----
L
D
V
-
L
D
-
G
-
T
R
L
K
PGN
I
A
Y
V
R
Q
Q
E
P
M
G
L
G
H
A
V
W
C
A
R
D
I
V
G
---
D
E
P
F
A
--
V
L
L
P
D
D
F
M
F
G
Q
P
G
C
L
--------
K
Q
M
V
D
A
Y
N
K
V
-
G
G
N
L
I
-
C
A
E
E
V
P
D
D
Q
T
H
R
Y
G
I
I
T
P
G
T
Q
D
G
-
V
----
L
T
E
V
K
G
L
V
E
K
P
A
P
G
T
-----
A
P
S
N
L
S
V
I
G
R
Y
I
L
Q
P
E
V
M
-
R
I
L
E
N
Q
---------
Q
L
T
D
A
M
Q
R
M
-
I
-
G
D
Q
P
F
H
G
-----------
V
T
F
--
Q
G
T
R
Y
D
C
G
D
K
A
G
F
I
Q
A
N
L
A
V
A
L
S
R
P
----
D
L
E
P
A
V
R
A
F
A
V
K
A
L
G
--------
29
PsiBlast_CBE
90.98
44%
-89
- C1 -
2UX8
1
?
C:
[14-293]
--
L
R
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
M
P
K
E
M
L
P
V
V
D
R
P
-
L
I
Q
Y
A
V
D
E
A
V
E
A
G
I
E
Q
M
I
F
V
T
G
R
G
K
-
S
A
L
E
D
H
F
D
I
A
Y
E
L
E
A
T
M
A
A
R
G
K
S
-----
L
D
V
-
L
D
-
G
-
T
R
L
K
PGN
I
A
Y
V
R
Q
Q
E
P
M
G
L
G
H
A
V
W
C
A
R
D
I
V
G
---
D
E
P
F
A
--
V
L
L
P
D
D
F
M
F
G
Q
P
G
C
L
--------
K
Q
M
V
D
A
Y
N
K
V
-
G
G
N
L
I
-
C
A
E
E
V
P
D
D
Q
T
H
R
Y
G
I
I
T
P
G
T
Q
D
G
-
V
----
L
T
E
V
K
G
L
V
E
K
P
A
P
G
T
-----
A
P
S
N
L
S
V
I
G
R
Y
I
L
Q
P
E
V
M
-
R
I
L
E
N
Q
G
--------
Q
L
T
D
A
M
Q
R
M
-
I
-
G
D
Q
P
F
H
G
-----------
V
T
F
--
Q
G
T
R
Y
D
C
G
D
K
A
G
F
I
Q
A
N
L
A
V
A
L
S
R
P
----
D
L
E
P
A
V
R
A
F
A
V
K
A
L
G
--------
3
PsiBlast_PDB
90.64
38%
-95
- C1 -
2PA4
2
?
A:
[12-299]
--
V
K
T
V
V
V
P
A
A
G
L
G
T
R
F
L
P
A
T
K
T
V
P
K
E
L
L
P
V
V
D
T
P
-
G
I
E
L
I
A
A
E
A
A
E
L
G
A
T
R
L
A
I
I
T
A
P
N
K
-
A
G
V
L
A
H
F
E
R
S
S
E
L
E
E
T
L
M
E
R
G
K
T
D
Q
V
E
I
I
R
R
-
A
A
-
D
L
I
K
A
V
-----
P
V
T
Q
D
K
P
L
G
L
G
H
A
V
G
L
A
E
S
V
L
D
---
D
D
E
D
V
V
A
V
M
L
P
D
D
L
--
V
L
P
T
G
V
M
E
R
----
M
A
Q
V
R
A
E
F
----
G
G
S
V
L
-
C
A
V
E
V
S
E
A
D
V
S
K
Y
G
I
F
E
I
E
A
D
-
T
-
K
-
D
S
D
V
K
K
V
K
G
M
V
E
K
P
A
I
E
D
-----
A
P
S
R
L
A
A
T
G
R
Y
L
L
D
R
K
I
F
-
D
A
L
R
R
I
T
P
-
G
A
G
G
E
L
Q
L
T
D
A
I
D
L
L
I
D
-
E
G
H
P
V
H
I
-----------
V
I
H
--
Q
G
K
R
H
D
L
G
N
P
G
G
Y
I
P
A
C
V
D
F
G
L
S
H
P
VY
G
A
Q
L
K
D
A
I
K
Q
I
L
A
E
H
E
A
A
-------
30
PsiBlast_CBE
90.19
44%
-89
- C1 -
2UX8
1
?
B:
[14-293]
--
L
R
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
M
P
K
E
M
L
P
V
V
D
R
P
-
L
I
Q
Y
A
V
D
E
A
V
E
A
G
I
E
Q
M
I
F
V
T
G
R
G
K
-
S
A
L
E
D
H
F
D
I
A
Y
E
L
E
A
T
M
A
A
R
G
K
S
-----
L
D
V
-
L
D
-
G
-
T
R
L
K
PGN
I
A
Y
V
R
Q
Q
E
P
M
G
L
G
H
A
V
W
C
A
R
D
I
V
G
---
D
E
P
F
A
--
V
L
L
P
D
D
F
M
F
G
Q
P
G
C
L
--------
K
Q
M
V
D
A
Y
N
K
V
-
G
G
N
L
I
-
C
A
E
E
V
P
D
D
Q
T
H
R
Y
G
I
I
T
P
G
T
Q
D
G
-
V
----
L
T
E
V
K
G
L
V
E
K
P
A
P
G
T
-----
A
P
S
N
L
S
V
I
G
R
Y
I
L
Q
P
E
V
M
-
R
I
L
E
N
Q
G
---------
L
T
D
A
M
Q
R
M
-
I
-
G
D
Q
P
F
H
G
-----------
V
T
F
--
Q
G
T
R
Y
D
C
G
D
K
A
G
F
I
Q
A
N
L
A
V
A
L
S
R
P
----
D
L
E
P
A
V
R
A
F
A
V
K
A
L
G
--------
25
PsiBlast_CBE
89.92
44%
-91
- C1 -
2UX8
1
?
G:
[14-293]
--
L
R
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
M
P
K
E
M
L
P
V
V
D
R
P
-
L
I
Q
Y
A
V
D
E
A
V
E
A
G
I
E
Q
M
I
F
V
T
G
R
G
K
-
S
A
L
E
D
H
F
D
I
A
Y
E
L
E
A
T
M
A
A
R
G
K
S
-----
L
D
V
-
L
D
-
G
-
T
R
L
K
PGNIA
Y
V
R
Q
Q
E
P
M
G
L
G
H
A
V
W
C
A
R
D
I
V
G
---
D
E
P
F
A
--
V
L
L
P
D
D
F
M
F
G
Q
P
G
C
L
--------
K
Q
M
V
D
A
Y
N
K
V
-
G
G
N
L
I
-
C
A
E
E
V
P
D
D
Q
T
H
R
Y
G
I
I
T
P
G
T
Q
D
G
-
V
----
L
T
E
V
K
G
L
V
E
K
P
A
P
G
T
-----
A
P
S
N
L
S
V
I
G
R
Y
I
L
Q
P
E
V
M
-
R
I
L
E
N
Q
G
K
-
G
A
G
G
E
I
Q
L
T
D
A
M
Q
R
M
-
I
-
G
D
Q
P
F
H
G
-----------
V
T
F
--
Q
G
T
R
Y
D
C
G
D
K
A
G
F
I
Q
A
N
L
A
V
A
L
S
R
P
----
D
L
E
P
A
V
R
A
F
A
V
K
A
L
G
--------
31
PsiBlast_CBE
89.87
38%
-100
- C1 -
2PA4
2
?
D:
[12-299]
--
V
K
T
V
V
V
P
A
A
G
L
G
T
R
F
L
P
A
T
K
T
V
P
K
E
L
L
P
V
V
D
T
P
-
G
I
E
L
I
A
A
E
A
A
E
L
G
A
T
R
L
A
I
I
T
A
P
N
K
-
A
G
V
L
A
H
F
E
R
S
S
E
L
E
E
T
L
M
E
R
---
D
Q
V
E
I
I
R
R
-
A
A
-
D
L
I
K
A
V
-----
P
V
T
Q
D
K
P
L
G
L
G
H
A
V
G
L
A
E
S
V
L
D
---
D
D
E
D
V
VA
V
M
L
P
D
D
L
--
V
L
P
T
G
V
M
E
R
----
M
A
Q
V
R
A
E
F
----
G
G
S
V
L
-
C
A
V
E
V
S
E
A
D
V
S
K
Y
G
I
F
E
I
E
A
D
-
T
-
K
-
D
S
D
V
K
K
V
K
G
M
V
E
K
P
A
I
E
D
-----
A
P
S
R
L
A
A
T
G
R
Y
L
L
D
R
K
I
F
-
D
A
L
R
R
I
T
P
-
G
A
G
G
E
L
Q
L
T
D
A
I
D
L
L
I
D
-
E
G
H
P
V
H
I
-----------
V
I
H
--
Q
G
K
R
H
D
L
G
N
P
G
G
Y
I
P
A
C
V
D
F
G
L
S
H
P
VYGA
Q
L
K
D
A
I
K
Q
I
L
A
E
H
E
A
A
E
R
I
----
26
PsiBlast_CBE
89.87
44%
-89
- C1 -
2UX8
1
?
F:
[14-293]
--
L
R
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
M
P
K
E
M
L
P
V
V
D
R
P
-
L
I
Q
Y
A
V
D
E
A
V
E
A
G
I
E
Q
M
I
F
V
T
G
R
G
K
-
S
A
L
E
D
H
F
D
I
A
Y
E
L
E
A
T
M
A
A
R
G
K
S
-----
L
D
V
-
L
D
-
G
-
T
R
L
K
PGN
I
A
Y
V
R
Q
Q
E
P
M
G
L
G
H
A
V
W
C
A
R
D
I
V
G
---
D
E
P
F
A
--
V
L
L
P
D
D
F
M
F
G
Q
P
G
C
L
--------
K
Q
M
V
D
A
Y
N
K
V
-
G
G
N
L
I
-
C
A
E
E
V
P
D
D
Q
T
H
R
Y
G
I
I
T
P
G
T
Q
D
G
-
V
----
L
T
E
V
K
G
L
V
E
K
P
A
P
G
T
-----
A
P
S
N
L
S
V
I
G
R
Y
I
L
Q
P
E
V
M
-
R
I
L
E
N
Q
G
K
-------
Q
L
T
D
A
M
Q
R
M
-
I
-
G
D
Q
P
F
H
G
-----------
V
T
F
--
Q
G
T
R
Y
D
C
G
D
K
A
G
F
I
Q
A
N
L
A
V
A
L
S
R
P
----
D
L
E
P
A
V
R
A
F
A
V
K
A
L
G
--------
32
PsiBlast_CBE
88.46
38%
-94
- C1 -
2PA4
2
?
C:
[12-299]
--
V
K
T
V
V
V
P
A
A
G
L
G
T
R
F
L
P
A
T
K
T
V
P
K
E
L
L
P
V
V
D
T
P
-
G
I
E
L
I
A
A
E
A
A
E
L
G
A
T
R
L
A
I
I
T
A
P
N
K
-
A
G
V
L
A
H
F
E
R
S
S
E
L
E
E
T
L
M
E
R
G
K
T
D
Q
V
E
I
I
R
R
-
A
A
-
D
L
I
K
A
V
-----
P
V
T
Q
D
K
P
L
G
L
G
H
A
V
G
L
A
E
S
V
L
D
---
D
D
E
D
V
V
A
V
M
L
P
D
D
L
--
V
L
P
T
G
V
M
E
R
----
M
A
Q
V
R
A
E
F
----
G
G
S
V
L
-
C
A
V
E
V
S
E
A
D
V
S
K
Y
G
I
F
E
I
E
A
D
-
T
-
K
-
D
S
D
V
K
K
V
K
G
M
V
E
K
P
A
I
E
D
-----
A
P
S
R
L
A
A
T
G
R
Y
L
L
D
R
K
I
F
-
D
A
L
R
R
I
T
P
-
G
A
G
G
E
L
Q
L
T
D
A
I
D
L
L
I
D
-
E
G
H
P
V
H
I
-----------
V
I
H
--
Q
G
K
R
H
D
L
G
N
P
G
G
Y
I
P
A
C
V
D
F
G
L
S
H
P
V
Y
G
A
Q
L
K
D
A
I
K
Q
I
L
A
E
H
E
A
A
E
R
I
----
24
PsiBlast_CBE
88.42
44%
-98
- C1 -
2UX8
1
?
H:
[14-293]
--
L
R
K
A
V
F
P
V
A
G
L
G
T
R
F
L
P
A
T
K
A
M
P
K
E
M
L
P
V
V
D
R
P
-
L
I
Q
Y
A
V
D
E
A
V
E
A
G
I
E
Q
M
I
F
V
T
G
R
G
K
-
S
A
L
E
D
H
F
D
I
A
Y
E
L
E
A
T
M
A
A
R
G
K
S
-----
L
D
V
-
L
D
-
G
-
T
R
L
K
PGNIA
Y
V
R
Q
Q
E
P
M
G
L
G
H
A
V
W
C
A
R
D
I
V
G
---
D
E
P
F
A
--
V
L
L
P
D
D
F
M
F
G
Q
P
G
C
L
--------
K
Q
M
V
D
A
Y
N
K
V
-
G
G
N
L
I
-
C
A
E
--------------------------
L
T
E
V
K
G
L
-------------------
V
I
G
R
Y
I
L
Q
P
E
V
M
-
R
I
L
E
N
----------
Q
L
T
D
A
M
Q
R
M
-
I
-
G
D
Q
P
F
H
G
-----------
V
T
F
--
Q
G
T
R
Y
D
C
G
D
K
A
G
F
I
Q
A
N
L
A
V
A
L
S
R
P
----
D
L
E
P
A
V
R
A
F
A
V
K
A
L
G
--------
40
HHSearch
88.37
38%
-88
- C1 -
2PA4
2
?
A:
[12-303]
--
V
K
T
V
V
V
P
A
A
G
L
G
T
R
F
L
P
A
T
K
T
V
P
K
E
L
L
P
V
V
D
T
P
-
G
I
E
L
I
A
A
E
A
A
E
L
G
A
T
R
L
A
I
I
T
A
P
N
K
-
A
G
V
L
A
H
F
E
R
S
S
E
L
E
E
T
L
M
E
R
G
K
T
D
Q
V
E
I
I
R
R
-
A
A
D
L
-
I
K
A
V
-----
P
V
T
Q
D
K
P
L
G
L
G
H
A
V
G
L
A
E
S
V
L
D
DD-
E
D
V
V
A
--
V
M
L
P
D
D
L
V
L
P
-----
T
G
V
----
M
E
R
M
A
Q
V
R
A
E
F
-
G
G
S
V
L
-
C
A
V
E
V
S
E
A
D
V
S
K
Y
G
I
F
E
I
E
A
D
-
T
K
D
-
S
D
-
V
K
K
V
K
G
M
V
E
K
P
A
I
E
D
-----
A
P
S
R
L
A
A
T
G
R
Y
L
L
D
R
K
I
F
-
D
A
L
R
R
I
T
P
-
G
A
G
G
E
L
Q
L
T
D
A
I
D
L
L
-
I
D
E
G
H
P
V
H
I
-----------
V
I
H
--
Q
G
K
R
H
D
L
G
N
P
G
G
Y
I
P
A
C
V
D
F
G
L
S
H
P
----
V
Y
G
A
Q
L
K
D
A
I
K
Q
I
L
A
E
H
E
A
A
---
33
PsiBlast_CBE
87.85
38%
-92
- C1 -
2PA4
2
?
B:
[12-299]
--
V
K
T
V
V
V
P
A
A
G
L
G
T
R
F
L
P
A
T
K
T
V
P
K
E
L
L
P
V
V
D
T
P
-
G
I
E
L
I
A
A
E
A
A
E
L
G
A
T
R
L
A
I
I
T
A
P
N
K
-
A
G
V
L
A
H
F
E
R
S
S
E
L
E
E
T
L
M
E
R
G
K
T
D
Q
V
E
I
I
R
R
-
A
A
-
D
L
I
K
A
V
-----
P
V
T
Q
D
K
P
L
G
L
G
H
A
V
G
L
A
E
S
V
L
D
---
D
D
E
D
V
V
A
V
M
L
P
D
D
L
--
V
L
P
T
G
V
M
E
R
----
M
A
Q
V
R
A
E
F
----
G
G
S
V
L
-
C
A
V
E
V
S
E
A
D
V
S
K
Y
G
I
F
E
I
E
A
D
-
T
-
K
-
D
S
D
V
K
K
V
K
G
M
V
E
K
P
A
I
E
D
-----
A
P
S
R
L
A
A
T
G
R
Y
L
L
D
R
K
I
F
-
D
A
L
R
R
I
T
P
-
G
A
G
G
E
L
Q
L
T
D
A
I
D
L
L
I
D
-
E
G
H
P
V
H
I
-----------
V
I
H
--
Q
G
K
R
H
D
L
G
N
P
G
G
Y
I
P
A
C
V
D
F
G
L
S
H
P
VY
G
A
Q
L
K
D
A
I
K
Q
I
L
A
E
H
E
A
A
E
R
I
----
41
HHSearch
72.00
24%
-97
- C1 -
1LVW
8
?
A:
[1-244]
G
A
H
M
K
G
I
V
L
A
G
G
S
G
T
R
L
Y
P
I
T
R
A
V
S
K
Q
L
L
P
I
Y
D
K
P
-
M
I
Y
Y
P
L
S
V
L
M
L
A
G
I
R
D
I
L
I
I
S
T
P
R
D
L
P
L
Y
R
D
L
L
G
D
G
S
---------------------
Q
F
-
G
-
V
R
F
S
-----
Y
R
V
Q
E
E
P
R
G
I
A
D
A
F
I
V
G
K
D
F
I
G
---
D
S
K
V
A
--
L
V
L
G
D
N
V
F
Y
G
------
H
R
----
F
S
E
I
L
R
R
A
A
S
L
E
D
G
A
V
I
-
F
G
Y
Y
--
V
R
D
P
R
P
F
G
V
V
E
F
D
S
---------
E
G
R
V
I
S
I
E
E
K
P
S
--
R
-----
P
K
S
N
Y
V
V
P
G
L
Y
F
Y
D
N
Q
V
V
-
E
I
A
R
R
I
E
P
-
S
D
R
G
E
L
E
I
T
S
V
N
E
E
Y
-
L
-
R
M
G
K
L
R
V
-----------
E
L
M
GR
G
M
A
W
L
D
T
G
T
H
D
G
L
L
E
A
S
S
F
I
E
T
I
Q
K
----
R
Q
G
F
Y
I
A
C
L
E
E
I
A
Y
N
N
G
W
I
T
R
E
D
47
HHSearch
70.57
22%
-89
- C1 -
3BRK
1
GLGC_RHIRD
X:
[10-288]
A
R
D
A
M
A
Y
V
L
A
G
G
R
G
S
R
L
K
E
L
T
D
R
R
A
K
P
A
V
Y
F
G
G
K
A
R
I
I
D
F
A
L
S
N
A
L
N
S
G
I
R
R
I
G
V
A
T
Q
Y
K
A
-
H
S
L
I
R
H
L
Q
R
G
W
D
F
F
R
P
E
------------
R
N
-
E
--
S
-
F
D
I
L
PAS-------
W
Y
E
G
T
A
D
A
V
Y
Q
N
I
D
I
I
E
PYA
P
E
Y
M
V
--
I
L
A
G
D
H
I
Y
K
M
-------
D
----
Y
E
Y
M
L
Q
Q
H
V
D
S
G
A
D
V
T
I
-
G
C
L
E
V
P
R
M
E
A
T
G
F
G
V
M
H
V
N
E
---------
K
D
E
I
I
D
F
I
E
K
P
A
D
P
P
GIPGN
E
G
F
A
L
A
S
M
G
I
Y
V
F
H
T
K
F
L
M
E
A
V
R
R
D
A
A
D----------
I
I
P
Y
I
-
V
-
E
H
G
K
A
V
A
HRFADSCVRSD
F
E
H
--
E
P
Y
W
R
D
V
G
T
I
D
A
Y
W
Q
A
N
I
D
L
T
D
V
V
P
----
D
L
D
I
Y
D
K
S
W
P
I
W
T
Y
A
E
I
T
P
P
A
K
F