@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Rv3281: (2016-05-18 )
MGTCPCESSERNEPVSRVSGTNEVSDGNETNNPAEVSDGNETNNPAEVSDGNETNNPAPVSRVSGTNEVSDGNETNNPAPVSRVSGTNEVSDGNETNNPAPVTEKPLHPHEPHIEILRGQPTDQELAALIAVLGSISGSTPPAQPEPTRWGLPVDQLRYPVFSWQRITLQEMTHMRR
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------....-.....10..--......20...--.....30.....----...40........50.-.......60-----......-----..70...----------...---------..80........90.---.......100---.......-----110.....-..120.........130---------.----.......140.......-150------.......160...-.-------...170.....--------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGTC-PCESSERNE--PVSRVSGTNEV--SDGNETNNPAEV----SDGNETNNPAEVSDGN-ETNNPAPVS-----RVSGTN-----EVSDGNE----------TNN---------PAPVSRVSGTNEVSD---GNETNNPAPV---TEKPLHP-----HEPH
I
E
I
L-RGQ--P
T
D
Q
E
L
A
A
L
I
A
----------
V
----
L
G
S
ISGSTPPAQPEPTR-WGL------
P
V
D
Q
LRYPVF
S
W
Q
-R-------
I
T
L
Q
E
M
T
HMRR--------------------------------------------------------------
2
PsiBlast_PDB
68.38
21%
30
- C6 -
4KUH
1
?
A:
[60-204]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
K
E
E
--
I
L
S
R
I
S
G
T
T
D
M
--
K
L
A
A
D
C
D
L
V
V
E
A
----
A
I
E
N
M
K
I
K
K
E
I
F
A
E
L
D
-
G
I
C
K
P
E
T
I
------
L
A
S
N
T
S
-----
S
L
S
-----------------------------
I
T
E
V
A
S
A
T
K
R
A
D
K
V
I
G
M
H
F
F
N
P
A
P
V
---
M
K
-------------
L
V
E
V
I
-
R
G
A
--
A
T
S
Q
E
T
F
D
A
V
K
----------
E
----
M
S
E
S
I
G
K
T
P
V
E
V
A
E
A
P
---
G
F
------
V
V
N
R
I
L
I
P
M
I
N
E
A
-
T
-------
F
I
L
Q
E
--------------------------------------------------------------------
3
PsiBlast_PDB
67.52
21%
32
- C6 -
4KUE
-
?
A:
[60-204]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
K
E
E
--
I
L
S
R
I
S
G
T
T
D
M
--
K
L
A
A
D
C
D
L
V
V
E
A
----
A
I
E
N
M
K
I
K
K
E
I
F
A
E
L
D
-
G
I
C
K
P
E
T
I
------
L
A
S
N
T
S
-----
S
L
S
-----------------------------
I
T
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V
A
S
A
T
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R
A
D
K
V
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M
H
F
F
N
P
A
P
V
---
M
K
-------------
L
V
E
V
I
-
R
G
A
--
A
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Q
E
T
F
D
A
V
K
----------
E
----
M
S
E
S
I
G
K
T
P
V
E
V
A
E
A
P
---
G
F
------
V
V
N
R
I
L
I
P
M
I
N
E
A
-
T
-------
F
I
L
Q
E
--------------------------------------------------------------------
4
PsiBlast_PDB
67.28
21%
29
- C6 -
4R1N
-
?
A:
[60-204]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
K
E
E
--
I
L
S
R
I
S
G
T
T
D
M
--
K
L
A
A
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C
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L
V
V
E
A
----
A
I
E
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M
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E
I
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A
E
L
D
-
G
I
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K
P
E
T
I
------
L
A
S
N
T
S
-----
S
L
S
-----------------------------
I
T
E
V
A
S
A
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K
R
A
D
K
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M
H
F
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N
P
A
P
V
---
M
K
-------------
L
V
E
V
I
-
R
G
A
--
A
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E
T
F
D
A
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K
----------
E
----
M
S
E
S
I
G
K
T
P
V
E
V
A
E
A
P
---
G
F
------
V
V
N
R
I
L
I
P
M
I
N
E
A
-
T
-------
F
I
L
Q
E
--------------------------------------------------------------------
1
PsiBlast_PDB
66.89
21%
29
- C6 -
4KUG
1
?
A:
[60-204]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
K
E
E
--
I
L
S
R
I
S
G
T
T
D
M
--
K
L
A
A
D
C
D
L
V
V
E
A
----
A
I
E
N
M
K
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K
K
E
I
F
A
E
L
D
-
G
I
C
K
P
E
T
I
------
L
A
S
N
T
S
-----
S
L
S
-----------------------------
I
T
E
V
A
S
A
T
K
R
A
D
K
V
I
G
M
H
F
F
N
P
A
P
V
---
M
K
-------------
L
V
E
V
I
-
R
G
A
--
A
T
S
Q
E
T
F
D
A
V
K
----------
E
----
M
S
E
S
I
G
K
T
P
V
E
V
A
E
A
P
---
G
F
------
V
V
N
R
I
L
I
P
M
I
N
E
A
-
T
-------
F
I
L
Q
E
--------------------------------------------------------------------
22
Fugue
60.23
18%
7
- C4 -
4CUA
8
?
A:
[4-181]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
G
A
--
N
I
S
D
Q
W
T
G
S
E
L
--
P
-------
L
A
F
A
----
S
D
S
N
P
S
D
P
V
S
N
V
N
D
K
L
-
I
S
Y
N
N
Q
P
A
N
-----
R
W
T
-----------
N
W
N
R
----------
S
N
P
---------
E
A
S
V
G
V
L
F
G
D
S
G
I
L
S
---
K
R
S
V
D
N
L
S
V
G
F
H
E
D
H
G
V
G
A
P
-----
K
S
Y
V
I
E
Y
Y
-
V
G
K
TV
P
T
A
P
K
N
P
S
F
V
G
NEDHVFNDSA
N
----
W
K
P
V
T
N
L
K
A
P
A
Q
L
K
A
G
E
M
N
H
F
------
S
F
D
K
V
E
T
Y
A
I
R
I
R
M
V
K
ADNKR
G
T
S
I
T
E
V
Q
I
F
A
K
--------------------------------------------------------------
19
Fugue
51.47
12%
-7
- C3 -
4UW8
2
FIBL1_BPT5
A:
[20-427]
C
S
F
G
I
E
N
TAG
G
S
A
V
F
H
N
Y
T
R
G
A
SNSVTKNNQLL
G
G
Y
G
S
R
P
W
LGSTYTEHSN
A
A
L
H
F
L
G
AGDTSATNH
G
G
W
I
R
L
L
V
T
P
KGKTISDRVPAFRLSDNG
D
L
W
L
V
P
DGAMHSDLGLVRS
I
E
T
L
N
A
A
V
PRFNAPSIQDGR
G
L
K
I
V
A
PQ
A
P
E
I
D
L
I
A
P
RGSGAS
A
P
A
I
R
A
M
W
C
D
G
SLADTTR
Y
I
G
A
TQPG
S
T
F
Y
I
G
-
A
S
G
H
D
G
E
K
F
--
D
S
M
R
G
S
V
A
I
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--
A
G
G
W
G
P
T
S
T
P
T
Q
----
V
V
L
E
T
C
E
S
G
S
I
S
R
L
P
R
-
W
G
V
D
H
N
G
T
L
-----
M
P
M
A
D
N
-----
R
Y
N
L
G
W
G
----------
S
G
R
---------
V
K
Q
V
Y
A
V
N
G
T
I
N
T
A
D
---
A
R
L
K
N
D
V
R
A
M
---
S
---------------------------
D
P
E
T
E
A
A
K
A
----------
I
----
A
K
E
I
G
F
W
T
W
K
I
R
E
---
H
-
C
G
L
------
T
V
Q
R
A
I
-
E
I
M
E
S
F
-
G
-------
L
D
P
F
K
Y
G
F
I
C
Y
D
K
W
D
EHTVVSEYGPANEDGT
E
N
P
I
Y
K
T
I
P
A
G
D
H
Y
S
F
R
L
E
E
L
N
L
F
I
A
K
G
F
E
A
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S
A
I
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D
K
L
GM
27
Fugue
50.57
14%
9
- C1 -
1BRM
-
DHAS_ECOLI
A:
[134-354]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N
C
T
V
S
L
M
L
M
-
S
L
G
G
L
F
A
N
D
--
L
V
D
W
V
S
V
A
T
Y
Q
--
A
A
S
G
G
G
A
R
H
M
R
E
----
L
L
T
Q
M
G
H
L
Y
G
H
V
A
D
E
L
-
A
T
P
S
S
A
I
L
D
-----
I
E
R
K
V
T
-----
T
L
T
R
S
G
E
LPVDNFGVPL
A
G
S
---------
L
I
P
W
I
D
W
K
G
Q
A
E
T
N
K
---
I
L
N
T
S
S
V
I
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---
D
G
L
C
V
R
V
GAL
R
C
H
S
Q
A
F
T
I
K
L
K
K
D
--
V
S
I
P
T
V
E
E
L
L
A
----------
A
H
NPW
A
K
V
V
P
N
D
R
E
I
T
M
R
E
L
T
P
-
A
A
V
TGTL
T
T
P
V
G
R
L
R
K
L
N
M
G
P
E
-
F
-------
L
S
A
F
T
V
G
D
Q
L
L
WG------------------------------------------------------------
5
PsiBlast_PDB
48.19
42%
-41
* C7 *
3VVM
-
DCSE_STRLA
A:
[78-133]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
--
P
V
D
T
D
L
W
H
V
I
C
----------
V
N
S
--
L
G
S
C
K
G
S
T
G
P
A
S
T
D
P
-
R
-
T
G
E
------
P
Y
-
R
L
S
F
P
E
L
S
I
E
-
D
-------
I
A
-----------------------------------------------------------------------
6
PsiBlast_PDB
47.79
42%
-45
- C7 -
3VVL
-
DCSE_STRLA
A:
[78-133]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
--
P
V
D
T
D
L
W
H
V
I
C
----------
V
N
S
--
L
G
S
C
K
G
S
T
G
P
A
S
T
D
P
-
R
-
T
G
E
------
P
Y
-
R
L
S
F
P
E
L
S
I
E
-
D
-------
I
A
-----------------------------------------------------------------------
7
PsiBlast_PDB
44.05
25%
87
* C5 *
2XTL
1
?
A:
[143-265]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
N
N
-
P
T
I
E
N
E
P
K
E
G
I
P
V
D
K
K
I
T
V
N
K
T
W
A
V
D
G
N
E
V
N
K
A
D
E
T
----
V
D
A
V
F
T
---
L
Q
V
K
D
G
D
-
K
W
V
N
V
D
S
A
K
-----
A
T
A
A
T
S
F
K
H
T
F
E
N
L
D
N
A
K
----------
T
Y
R
V
I
E
R
V
S
G
Y
A
P
E
Y
V
S
F
V
N
G
V
V
T
I
K
N
---
N
K
D
S
N
E
P
T
P
I
--------
N
P
-----
S
E
P
K
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
41.09
30%
-91
- C6 -
1G6U
-
?
A:
[14-33]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
G
--
F
S
P
E
E
L
A
A
L
E
S
----------
E
----
L
Q
A
L
E
---------------------------------------------------------------------------------------------------------------------
16
HHSearch
40.69
13%
-108
* C6 *
2KVC
-
?
A:
[26-55]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
-----
S
F
A
V
L
A
L
L
-
C
R
R
--
L
S
H
D
E
V
K
A
V
A
N
----------
E
----
L
M
R
L
G
---------------------------------------------------------------------------------------------------------------------
12
HHSearch
39.33
33%
-63
- C6 -
1DW0
1
SHP_RHOS4
A:
[94-111]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
D
--
C
T
P
G
E
K
A
D
L
L
A
----------
W
----
L
A
A
-----------------------------------------------------------------------------------------------------------------------
17
HHSearch
39.12
21%
-88
- C6 -
2LKY
-
?
A:
[29-57]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-----
R
V
P
L
L
A
L
L
-
T
R
R
--
L
T
N
D
E
I
K
A
I
A
E
----------
D
----
L
E
K
R
A
---------------------------------------------------------------------------------------------------------------------
14
HHSearch
38.38
11%
-114
- C6 -
3M20
-
?
A:
[1-27]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
L
I
V
Y
-
G
P
K
--
L
D
V
G
K
K
R
E
F
V
E
----------
R
----
L
T
S
V
A
A
--------------------------------------------------------------------------------------------------------------------
25
Fugue
36.24
14%
49
- C2 -
2XQH
4
?
A:
[23-280]
-----------------------------------------------------------------------------------------------------------------------------------------------SDAKASGEF
S
V
A
V
G
NG
A
R
A
T
E
KA
S
T
A
V
G
SWAAADGKQ
S
T
A
L
G
V
G
T
Y
A
Y
A
N
A
S
T
A
L
G
--
S
V
A
F
V
D
N
T
--
A
--
T
Y
G
T
A
A
G
N
R
A
K
V
DKDA
T
E
G
T
A
L
G
A
K
A
T
V
T
N
K
N
S
V
A
L
G
A
N
S
V
T
T
R
DNE
V
Y
I
G
Y
K
-----
T
G
T
E
S
D
K
----------
T
Y
G
---------
T
R
V
L
G
G
L
S
D
G
T
R
N
S
D
---
A
A
T
V
G
Q
L
N
R
K
---
V
G
G
V
Y
D
D
-----
V
K
A
R
I
T
V
E
-
S
E
K
--
Q
K
K
Y
T
D
Q
K
T
S
E
----------
V
----
N
E
K
V
E
A
R
T
T
V
G
V
D
S
D
G
K
-
L
T
R
------
A
E
G
A
T
K
T
I
A
V
N
D
G
-
L
-------
V
A
L
S
G
R
T
D
R
I
D
Y
A
V
G
A
I
D
G
R
V
T
R
N
T
Q
S
I
E
K
N
S
K
A
I
A
A
N
T
RT--------------------------------
9
HHSearch
35.99
22%
-58
- C6 -
4N0K
2
CYC1_YEAST
A:
[89-106]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
--
K
K
E
K
D
R
N
D
L
I
T
----------
Y
----
L
K
K
A
----------------------------------------------------------------------------------------------------------------------
11
HHSearch
34.96
24%
-64
- C6 -
1GKS
1
CY551_HALHA
A:
[60-76]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
--
A
D
R
E
D
L
V
K
A
I
E
----------
Y
----
M
L
S
-----------------------------------------------------------------------------------------------------------------------
13
HHSearch
31.11
37%
-19
- C6 -
2YK3
2
CYC_CRIFA
A:
[96-113]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
M
--
K
K
P
Q
E
R
A
D
V
I
A
----------
Y
----
L
E
T
L
K
---------------------------------------------------------------------------------------------------------------------
8
HHSearch
30.67
24%
-38
- C6 -
3OL3
5
?
A:
[72-100]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
N
A
V
H
Q
I
I
-
E
K
E
--
P
T
A
E
E
I
N
Q
V
A
A
----------
R
----
L
A
S
V
G
W
--------------------------------------------------------------------------------------------------------------------