@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : PA1968: (2016-02-03 )
MQQVAKRAMTDTPDDRTGEASGLSKRQAFHRQHRQRAEEEARRLLDARAEQGGRWLDWVAGQLYLLRPPEYAAMVRRELQRLSGD
Atome Classification :
(19 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------...-......10....-------....20........30........40....-...---------.50......--..60......--.---.------------70-.--........80....------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
Q
-
V
A
K
R
AMTDTPDD-------RTGEASG
L
S
K
R
Q
A
F
H
R
Q
H
R
Q
R
A
E
E
E
A
R
R
L
L
-
D
A
R
---------
A
EQGGR
W
L
D
--
W
VAG
Q
L
Y
L
LR--P---
P
------------
E
--
Y
--
A
A
M
V
R
R
E
L
Q
R
LSGD------------------------------------------------------------------------------------------------
21
Fugue
75.02
15%
-23
- C3 -
3VKG
7
?
A:
[47-3244]
E
I
D
S
L
K
E
TAWSAIIPA
F
D
H
A
Q
N
L
I
K
I
Y
L
K
G
N
A
I
I
T
D
L
H
SEAIK
D
R
H
W
K
I
L
K
K
R
L
NTNWIITELT
L
G
S
I
W
D
S
DLARN
E
N
I
Y
R
E
V
I
T
A
A
Q
G
E
I
A
L
E
E
F
L
K
G
V
R
E
F
W
T
TLELD
L
V
N
Y
QRK
C
K
L
V
R
G
W
D
D
L
F
N
K
L
A
E
H
L
N
S
I
S
A
M
KMSPYYKVF
E
E
E
A
N
H
W
D
D
R
L
N
K
V
R
S
L
L
D
V
W
I
D
V
Q
R
R
W
V
Y
LEGIFINQLL
P
A
E
S
T
R
F
K
S
I
N
S
E
F
I
A
I
L
K
K
V
S
G
A
PL
I
L
E
V
L
A
IER
I
Q
Q
T
M
E
R
L
S
D
L
L
G
K
V
Q
K
A
L
G
E
Y
L
E
R
Q
R
S
A
F
A
R
F
Y
F
V
G
D
E
D
L
L
E
I
I
G
N
S
KDIIKIQKHFRKMFAGLA
N
L
T
L
D
DEKTTII
G
M
S
S
AEG
E
T
V
T
F
K
K
P
I
S
IANGPK
I
H
E
W
L
T
M
V
E
S
E
M
K
S
T
L
A
T
L
L
S
E
S
L
Q
H
F
N
Q
VDVNDHS
K
Y
S
E
W
V
D
N
Y
P
T
Q
L
V
L
L
T
S
Q
I
V
W
S
T
Q
V
D
Q
A
L
GGGTLQ
Q
S
K
I
Q
E
Q
L
Q
S
I
E
Q
T
T
Q
M
I
L
N
N
L
A
D
S
VLQDLS
A
Q
K
R
K
K
F
E
H
L
I
T
E
L
V
H
Q
R
D
V
V
R
Q
L
Q
K
CKNLTGNKDF
D
W
L
Y
H
M
R
Y
Y
Y
D
ATQENVLHK
L
V
I
H
M
AN
A
T
F
Y
YGFEYLGIGERLVQT
P
L
T
D
R
C
Y
L
T
L
T
Q
A
L
E
S
R
M
G
G
N
P
F
G
P
A
GTG
K
T
E
T
V
K
A
L
G
S
Q
L
G
R
F
V
L
V
F
C
CDEGFD
L
Q
A
M
S
R
I
F
V
G
L
C
Q
C
G
A
W
G
C
F
D
EFNRLE
E
R
I
L
S
A
V
S
Q
Q
I
Q
T
I
Q
V
A
L
K
E
NSKEVELLN
I
S
L
H
QD
M
G
I
F
V
T
M
N
P
GYAGRSNLPDNLKKL
F
R
S
M
A
M
IKPD
R
E
M
I
A
Q
V
M
L
Y
S
Q
GFKT
A
E
V
L
A
G
K
I
V
P
L
F
K
L
C
Q
E
QLSAQSHYDFG
L
R
A
L
K
S
V
L
V
S
A
G
G
I
K
R
K
CQPPD
A
E
S
K
T
K
A
D
Q
I
Y
C
Q
Y
E
I
G
V
L
L
N
S
I
N
D
TMIPKLVADD
I
P
L
I
Q
S
L
L
L
D
V
F
PG
S
Q
L
Q
P
I
QM
D
Q
L
R
K
K
I
Q
E
I
A
K
Q
R
HLVTK
Q
E
W
V
E
K
I
L
Q
L
H
Q
I
L
N
I
NH
G
V
M
M
V
G
P
S
GGG
K
T
T
S
W
E
V
Y
L
E
A
I
E
Q
V
DN
I
K
S
E
A
H
V
M
DPKAITKDQLF
G
S
L
D
LTTR
E
W
T
D
G
L
F
T
A
T
L
R
R
I
I
D
NVRGEST
K
R
H
W
I
I
F
D
G
D
V
D
PEWVENLNSLLDDNK
L
L
T
L
PNGE
R
L
A
L
P
NN
V
R
V
M
F
E
V
QDLKYATLATISR
C
G
M
V
W
F
S
EEILT
T
Q
M
I
F
Q
N
Y
L
D
T
L
S
N
E
PFD
P
Q
E
K
E
Q
Q
K
R
N
E
N
AIP
A
G
L
K
V
Q
K
E
C
A
A
I
I
SQYFEPGG
L
V
H
K
V
L
E
D
A
G
Q
RPHIMDFT
R
L
R
V
L
N
S
F
F
S
L
M
N
R
S
I
V
N
V
I
E
Y
N
Q
L
HSDFPMS
P
E
N
Q
S
N
Y
I
T
N
R
L
L
Y
S
L
M
W
GLGGSMG
L
V
E
R
E
N
F
S
K
F
I
Q
T
I
AITPVPANTIPLLD
Y
S
V
S
IDDA
N
W
S
L
WKNKVEVETHKVASPDVVIPT
V
D
T
T
R
H
V
D
V
L
H
A
W
L
S
E
HRP
L
I
L
C
G
P
PGSG
K
T
M
T
L
T
S
T
L
R
A
F
P
D
F
E
V
V
S
L
N
F
S
SATT
P
E
L
L
L
K
T
F
D
H
H
C
E
Y
K
R
T
PSG
E
T
V
L
R
P
TQLG
K
W
L
V
V
F
C
D
EINL
P
S
T
D
KYGTQ
R
V
I
T
F
I
R
Q
M
V
E
KGGFWRTSDH
T
W
I
K
L
D
K
I
Q
F
V
G
A
C
N
PPTDAGRVQLTHRFLRH
A
P
I
L
L
V
D
F
PS
T
S
S
L
T
Q
I
Y
G
T
F
N
R
A
L
M
KLLPNLRSF
A
D
N
L
T
D
A
M
V
E
F
Y
S
E
S
Q
K
R
F
TPDIQAHYIYSP
R
E
L
S
R
W
D
R
A
L
L
E
A
I
Q
T
MDGCT
L
E
G
L
V
R
L
W
A
H
E
A
L
R
L
FQDRLVE
T
E
E
K
E
W
T
D
K
K
I
D
E
V
A
L
K
H
F
PSVNLDALKRPILYSNWLTPVN
R
S
D
L
R
E
Y
V
K
A
R
L
K
V
F
YPLVLF
N
E
V
L
D
H
I
L
R
I
D
R
V
F
R
Q
PQG
H
A
L
L
I
G
V
SGGG
K
S
V
L
S
R
F
V
A
W
M
N
G
L
S
I
Y
T
I
KYK
S
S
D
F
D
D
D
L
R
M
L
L
K
R
A
GCKE
E
K
I
C
F
I
F
D
ESNVLE
S
S
F
L
E
R
M
N
T
L
L
A
GGEVPGLFE
G
E
E
F
T
A
L
M
H
A
C
K
E
T
A
Q
R
N
GLILDS
E
E
E
L
Y
K
Y
F
T
S
Q
V
R
R
N
L
H
V
V
F
T
M
N
PASPDFHNS
P
A
L
F
N
R
C
VLDWFGEWS
P
E
A
L
F
Q
V
G
S
E
F
T
RNLDLENPQ
Y
I
A
P
P
V
F
I
Q
E
A
EILMAIPPS
H
R
D
A
V
V
S
S
L
V
Y
I
H
Q
T
I
G
E
A
N
I
R
L
L
K
R
QG
R
Q
N
Y
V
T
P
R
H
Y
L
D
F
I
N
Q
V
V
L
L
I
N
E
K
R
D
Q
L
E
E
E
Q
L
H
L
N
I
G
L
K
K
L
R
D
T
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A
Q
V
K
D
L
Q
V
S
L
A
Q
K
N
R
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L
D
V
K
N
E
Q
A
N
Q
K
L
K
Q
M
V
Q
D
Q
Q
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A
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I
K
Q
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D
A
R
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L
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L
D
V
R
N
K
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I
A
V
Q
K
V
K
A
Y
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D
LP
L
R
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V
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Q
L
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N
A
A
N
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L
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L
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D
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V
A
T
I
T
A
L
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I
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A
T
L
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N
K
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A
L
L
D
N
L
N
S
E
R
G
R
W
E
Q
Q
S
E
N
F
N
T
Q
M
S
T
V
V
G
D
V
V
L
A
S
A
F
L
A
YIGFFD
Q
N
F
R
T
D
L
M
R
K
W
M
I
R
L
D
S
V
GIKFKSDLS
V
P
S
F
L
SK
P
E
E
R
L
N
W
H
A
N
SLPSD
E
L
C
I
E
N
A
I
M
L
K
RFNRYPLVIDPSG
Q
A
M
E
F
L
M
N
Q
Y
A
DKKITKTSF
M
K
N
L
E
S
A
L
R
F
G
C
P
L
L
V
Q
DVES
F
M
I
F
L
F
T
RDPT
A
H
F
T
P
D
L
C
S
R
V
T
F
V
N
FTVT
P
S
S
L
Q
S
Q
C
L
H
E
A
L
K
T
ERP
D
T
H
K
K
R
S
DLLKIQGEFQVKLR
I
L
E
K
S
L
L
N
A
L
S
Q
A
SGNILDD
D
S
V
I
S
T
L
E
T
L
K
K
E
TT
E
I
A
L
K
V
E
E
T
E
T
V
M
Q
E
I
S
E
V
S
A
L
Y
N
P
M
A
L
S
C
S
R
V
Y
F
A
M
E
E
L
SQFHL
Y
Q
F
S
L
R
A
F
L
D
I
F
Y
N
L
L
NNNPNLVDKKD
P
N
E
R
L
V
Y
L
S
K
D
I
F
S
M
T
F
N
R
V
T
R
T
LLNDD
K
L
T
F
A
L
Q
L
T
I
I
S
V
KGTSNEIE
E
S
E
W
D
F
L
L
KGGDNLTSIKETIPQLDSLLS
T
T
Q
Q
K
W
L
I
C
L
R
Q
QVPSFSK
L
V
D
H
I
Q
Q
N
SSDWKQFFGKDQVGEPIIP
E
S
W
I
V
A
Q
A
Q
L
S
NQQS
T
I
V
S
N
F
R
K
I
L
L
M
K
A
FHSDR
V
L
Q
Y
S
H
S
F
V
C
S
V
FGEDFLNTLD
M
A
N
I
V
E
KEVKSS
S
P
L
L
LCSVPGYDA
S
S
K
V
D
D
L
A
L
Q
L
H
K
Q
Y
K
S
F
A
I
GSPEGFELAEK
S
I
Y
A
A
A
K
SG
T
W
V
L
L
K
NIHLAPQWL
V
Q
L
E
K
K
L
H
S
L
S
P
H
PS
F
R
L
F
M
T
S
E
IHPALP
A
N
L
L
R
M
S
N
V
F
S
Y
E
NPPG
V
K
A
N
L
L
H
T
F
I
G
IP
A
T
R
M
D
KQPAE
R
S
R
I
Y
F
L
L
A
W
F
H
A
I
I
Q
E
R
L
RYIPLGWTKFFEFN
D
A
D
L
R
G
A
L
D
S
I
D
Y
W
V
D
L
Y
SKGRSNIDPDKIP
W
I
A
V
R
T
I
L
G
STIYGGRIDN
E
F
D
M
R
L
L
Y
S
F
L
E
Q
L
F
TPSAFNPDFPLVPSIGL
S
V
P
E
G
TT
R
A
H
F
M
K
W
I
E
A
LPEISTPIWLGLPEN
A
E
S
L
L
L
S
N
K
A
R
K
M
I
N
D
L
Q
K
M
Q
S
S
E
E
DS
S
S
S
E
D
K
G
K
A
KP
L
F
R
-
C
F
E
R
E
I
S
T
G
G
K
L
-------
V
K
K
I
T
N
D
L
A
N
L
L
K
W
Y
S
V
P
E
T
I
S
L
S
V
W
I
S
D
F
-
S
K
R
---------
M
Q
Q
L
S
E
I
S
E
SV
W
L
G
G
---
L
L
N
--
P
---
E
------------
A
--
Y
--
I
T
A
T
R
Q
S
A
S
Q
L
N
G
R
LHASA
S
F
N
V
K
G
M
A
L
E
G
A
V
W
N
ND
Q
L
T
P
TDIL
S
T
P
I
S
I
A
T
L
T
W
K
DPIFNNSSS
K
L
S
V
P
V
Y
LNETRSELL
F
S
I
D
L
P
Y
DQSTS
K
Q
N
W
Y
Q
R
S
V
S
I
S
SWKSD
1
PsiBlast_PDB
56.49
34%
16
- C3 -
4KSA
-
?
A:
[41-86]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
S
E
T
L
L
S
-------
R
R
G
E
A
S
G
V
A
L
A
A
S
L
L
A
G
Y
E
A
A
D
E
D
D
K
L
A
F
L
-
D
A
L
---------
A
E
Q
F
G
P
D
L
A
--
E
L
N
T
A
I
E
A
F
R
--
A
---
D
------------
A
--
S
--
A
E
A
T
G
E
L
L
R
A
A
E
P
R
------------------------------------------------------------------------------------------------
20
Fugue
55.89
16%
-32
- C3 -
1MW5
-
Y1480_HAEIN
A:
[3-164]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETDLLMKVRQPVKLYSVATLFHEFSEVITKLEHSVQKEPTSLLSEENWHKQFLKFAQALPAHGSASWLN
L
D
D
-
A
L
Q
A
V
V
G
N
S
--------------------
R
S
A
F
L
H
Q
L
I
A
K
L
K
S
R
H
L
Q
V
L
E
L
N
K
---------
I
G
S
E
P
L
D
L
S
--
N
L
P
A
P
F
Y
V
L
L
--
P
---
E
------------
S
--
F
--
A
A
R
I
T
L
L
V
Q
D
K
A
L
P
YVRVSMEYWHALEYKGELN-----------------------------------------------------------------------------
15
Fugue
54.91
17%
2
- C3 -
2JPF
-
?
A:
[1-106]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
Q
-
L
Q
E
H
A
P
S
H
A
N
L
D
VKWLDGL
R
A
G
S
M
A
L
Q
G
D
V
K
V
W
M
Q
N
L
E
D
L
H
T
R
R
P
D
E
F
T
-
A
R
L
---------
Q
Q
S
T
D
A
L
Y
S
--
H
L
E
A
Q
W
A
K
Q
H
GT
P
---
P
TASDVVGMPQ
W
Q
E
--
Y
--
T
A
M
L
R
E
R
F
A
G
L
D
T
I
------------------------------------------------------------------------------------------------
7
HHSearch
48.63
27%
-87
- C3 -
1X66
-
A:
[33-65]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
W
L
E
--
W
A
I
K
E
-
Y
S
L
M
--
E
IDT
S
------------
F
--
F
--
Q
N
M
D
G
K
E
L
C
K
M
N
K
E
------------------------------------------------------------------------------------------------
22
Fugue
47.51
29%
-9
* C3 *
3SL9
3
BCL9_HUMAN
C:
[7-33]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
D
G
L
S
Q
E
Q
L
E
H
R
E
R
S
L
Q
T
L
R
D
I
Q
R
M
L
-
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
46.47
14%
27
- C3 -
1MK0
2
TEV1_BPT4
A:
[1-97]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
S
G
I
Y
Q
I
K
N
T
L
N
N
K
V
-------
Y
V
G
S
A
K
D
F
E
K
R
W
K
R
H
F
K
D
L
E
K
G
C
H
S
S
I
K
L
Q
-
R
S
F
---------
N
K
H
G
N
V
------
F
E
C
S
I
L
E
E
I
--
P
---
Y
------------
E
--
K
--
D
L
I
I
E
R
A
N
F
W
I
K
E
L
NSKINGYNIADATFG---------------------------------------------------------------------------------
12
HHSearch
45.79
26%
-53
- C3 -
3UT4
-
?
A:
[72-106]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
N
D
I
M
W
K
Y
--
W
V
I
K
L
M
I
P
Y
L
--
I
---
Y
------------
P
--
N
--
K
Q
L
V
K
S
E
L
E
R
L
S
S
L
------------------------------------------------------------------------------------------------
5
HHSearch
41.77
26%
-89
- C3 -
2YTU
-
A:
[47-80]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Q
W
L
E
--
W
A
I
K
E
-
Y
S
L
M
--
E
IDT
S
------------
F
--
F
--
Q
N
M
D
G
K
E
L
C
K
M
N
K
E
------------------------------------------------------------------------------------------------
4
HHSearch
41.45
17%
-94
- C3 -
1SV0
-
POK_DROME
A:
[60-91]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
F
L
R
--
F
C
V
R
E
-
F
D
L
P
--
K
---
L
------------
D
FD
L
--
F
Q
M
N
G
K
R
L
C
L
L
T
--------------------------------------------------------------------------------------------------
9
HHSearch
38.45
23%
-91
- C3 -
1SXD
-
GABPA_MOUSE
A:
[195-226]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
H
W
V
V
--
W
V
M
K
E
F
-
S
M
T
--
D
---
I
------------
D
--
L
TT
L
N
I
S
G
R
E
L
C
S
L
N
--------------------------------------------------------------------------------------------------
10
HHSearch
38.07
16%
-54
- C3 -
2E2C
-
UBE2C_SPISO
A:
[146-176]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
L
N
--
A
Q
A
A
D
M
W
S
-
N
--
Q
---
T
------------
E
--
Y
--
K
K
V
L
H
E
K
Y
K
T
A
Q
S
D
------------------------------------------------------------------------------------------------
16
Fugue
37.86
6%
6
- C3 -
1F3C
-
DYL1_RAT
A:
[1-89]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M
C
D
R
-
K
A
V
I
K
N
A
D
M
S
E
E
-------
M
Q
Q
D
S
V
E
C
A
T
Q
A
L
E
K
Y
N
I
E
K
D
I
A
A
H
I
K
K
E
F
-
D
K
K
YNP
T
W
H
C
I
V
G
R
N
F
G
S
Y
V
T
--
H
E
T
K
H
F
I
Y
F
Y
--
L
---
G
------------
Q
--
V
--
A
I
L
L
F
K
S
G
------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
34.67
37%
-19
- C3 -
3GG7
2
?
A:
[124-158]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
S
R
R
A
E
S
E
V
L
N
C
L
-
E
A
N
---------
P
R
S
G
T
P
I
L
H
--
W
Y
S
G
S
V
T
E
L
R
--
R
---
A
------------
I
--
S
--
L
G
C
W
F
S
V
G
P
T
M
V
R
T
------------------------------------------------------------------------------------------------
14
Fugue
30.07
14%
-36
- C3 -
2AXT
117
PSBM_THEEB
M:
[1-36]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
V
N
Q
L
G
--
L
I
A
T
A
L
F
V
L
V
--
P
---
S
------------
V
--
F
--
L
I
I
L
Y
V
Q
T
E
S
Q
Q
K
S
S-----------------------------------------------------------------------------------------------
11
HHSearch
26.10
44%
-44
- C3 -
2DKX
-
A:
[33-48]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
W
L
L
--
W
T
E
H
Q
-
Y
R
L
P
--
P
---
M
------------
G
--
K
--
A
F
Q
E
L
A
G
K
E
L
C
A
M
S
------------------------------------------------------------------------------------------------
3
HHSearch
17.80
44%
30
- C1 -
2JPK
-
LCGB_LACLL
A:
[2-10]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
W
G
W
L
A
--
W
V
D
P
A
Y
E
F
I
K
--
G
---
F
------------
G
--
K
--
G
A
I
K
E
G
N
K
D
K
W
K
N
I
------------------------------------------------------------------------------------------------
8
HHSearch
16.19
7%
26
- C3 -
3WDN
-
GCSH_BOVIN
A:
[111-124]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
--
E
---
E
------------
A
--
Y
--
E
K
Y
I
K
S
I
E
E
-----------------------------------------------------------------------------------------------------
6
HHSearch
10.08
60%
96
- C2 -
2ROD
-
APR_MOUSE
B:
[20-29]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
---
P
------------
E
--
F
--
A
A
Q
L
R
K
--------------------------------------------------------------------------------------------------------