@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTH7: (2017-12-13 )
MSKTSVIYPGTFDPITNGHVDLVTRASRMFDEVVVAIAIGHHKNPLFSLEERVALAQSSLGHLSNVEFVGFDGLLVNFFKEQKATAVLRGLRAVSDFEYEFQLANMNRQLDPHFEAVFLTPSEQYSFISSTLIREIARLKGDVTKFVPQAVVEAFERKHQQGW
Atome Classification :
(61 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSK
T
S
V
IYPGTFDPITNG
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
IGHHKNP
L
F
S
L
E
E
R
V
A
L
A
Q
S
SLGHLSN
V
E
F
VGF
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
VSD
F
E
Y
E
F
Q
LANMNRQLDPHF
E
A
V
F
LTP
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
LK
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
HQQGW
1
PsiBlast_PDB
93.14
99%
-144
- C1 -
-
5H16
1
COAD_ACIBS
A:
[1-163]
M
S
K
T
R
V
I
Y
P
G
T
F
D
P
I
T
N
G
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
I
G
H
H
K
N
P
L
F
S
L
E
E
R
V
A
L
A
Q
S
S
L
G
H
L
S
N
V
E
F
V
G
F
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
D
P
H
F
E
A
V
F
L
T
P
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
L
K
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
H
Q
Q
G
W
30
PsiBlast_CBE
92.08
99%
-142
- C1 -
-
5H7X
1
COAD_ACIBS
B:
[9-171]
M
S
K
T
R
V
I
Y
P
G
T
F
D
P
I
T
N
G
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
I
G
H
H
K
N
P
L
F
S
L
E
E
R
V
A
L
A
Q
S
S
L
G
H
L
S
N
V
E
F
V
G
F
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
D
P
H
F
E
A
V
F
L
T
P
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
L
K
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
H
Q
Q
G
W
22
PsiBlast_CBE
91.79
99%
-145
- C1 -
-
5H16
1
COAD_ACIBS
E:
[1-163]
M
S
K
T
R
V
I
Y
P
G
T
F
D
P
I
T
N
G
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
I
G
H
H
K
N
P
L
F
S
L
E
E
R
V
A
L
A
Q
S
S
L
G
H
L
S
N
V
E
F
V
G
F
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
D
P
H
F
E
A
V
F
L
T
P
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
L
K
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
H
Q
Q
G
W
2
PsiBlast_PDB
91.56
99%
-139
- C1 -
-
5H7X
1
COAD_ACIBS
A:
[9-171]
M
S
K
T
R
V
I
Y
P
G
T
F
D
P
I
T
N
G
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
I
G
H
H
K
N
P
L
F
S
L
E
E
R
V
A
L
A
Q
S
S
L
G
H
L
S
N
V
E
F
V
G
F
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
D
P
H
F
E
A
V
F
L
T
P
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
L
K
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
H
Q
Q
G
W
29
PsiBlast_CBE
91.39
99%
-144
- C1 -
-
5H7X
1
COAD_ACIBS
C:
[9-171]
M
S
K
T
R
V
I
Y
P
G
T
F
D
P
I
T
N
G
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
I
G
H
H
K
N
P
L
F
S
L
E
E
R
V
A
L
A
Q
S
S
L
G
H
L
S
N
V
E
F
V
G
F
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
D
P
H
F
E
A
V
F
L
T
P
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
L
K
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
H
Q
Q
G
W
21
PsiBlast_CBE
91.31
99%
-142
- C1 -
-
5H16
1
COAD_ACIBS
F:
[1-163]
M
S
K
T
R
V
I
Y
P
G
T
F
D
P
I
T
N
G
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
I
G
H
H
K
N
P
L
F
S
L
E
E
R
V
A
L
A
Q
S
S
L
G
H
L
S
N
V
E
F
V
G
F
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
D
P
H
F
E
A
V
F
L
T
P
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
L
K
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
H
Q
Q
G
W
28
PsiBlast_CBE
91.07
99%
-143
- C1 -
-
5H7X
1
COAD_ACIBS
D:
[9-171]
M
S
K
T
R
V
I
Y
P
G
T
F
D
P
I
T
N
G
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
I
G
H
H
K
N
P
L
F
S
L
E
E
R
V
A
L
A
Q
S
S
L
G
H
L
S
N
V
E
F
V
G
F
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
D
P
H
F
E
A
V
F
L
T
P
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
L
K
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
H
Q
Q
G
W
26
PsiBlast_CBE
90.86
99%
-146
- C1 -
-
5H7X
1
COAD_ACIBS
F:
[9-171]
M
S
K
T
R
V
I
Y
P
G
T
F
D
P
I
T
N
G
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
I
G
H
H
K
N
P
L
F
S
L
E
E
R
V
A
L
A
Q
S
S
L
G
H
L
S
N
V
E
F
V
G
F
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
D
P
H
F
E
A
V
F
L
T
P
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
L
K
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
H
Q
Q
G
W
24
PsiBlast_CBE
90.75
99%
-144
- C1 -
-
5H16
1
COAD_ACIBS
C:
[3-163]
--
K
T
R
V
I
Y
P
G
T
F
D
P
I
T
N
G
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
I
G
H
H
K
N
P
L
F
S
L
E
E
R
V
A
L
A
Q
S
S
L
G
H
L
S
N
V
E
F
V
G
F
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
D
P
H
F
E
A
V
F
L
T
P
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
L
K
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
H
Q
Q
G
W
25
PsiBlast_CBE
90.60
99%
-143
- C1 -
-
5H16
1
COAD_ACIBS
B:
[3-163]
--
K
T
R
V
I
Y
P
G
T
F
D
P
I
T
N
G
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
I
G
H
H
K
N
P
L
F
S
L
E
E
R
V
A
L
A
Q
S
S
L
G
H
L
S
N
V
E
F
V
G
F
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
D
P
H
F
E
A
V
F
L
T
P
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
L
K
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
H
Q
Q
G
W
112
HHSearch
89.90
99%
-144
- C1 -
-
5H7X
1
COAD_ACIBS
E:
[9-171]
M
S
K
T
R
V
I
Y
P
G
T
F
D
P
I
T
N
G
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
I
G
H
H
K
N
P
L
F
S
L
E
E
R
V
A
L
A
Q
S
S
L
G
H
L
S
N
V
E
F
V
G
F
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
D
P
H
F
E
A
V
F
L
T
P
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
L
K
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
H
Q
Q
G
W
27
PsiBlast_CBE
89.90
99%
-144
- C1 -
-
5H7X
1
COAD_ACIBS
E:
[9-171]
M
S
K
T
R
V
I
Y
P
G
T
F
D
P
I
T
N
G
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
I
G
H
H
K
N
P
L
F
S
L
E
E
R
V
A
L
A
Q
S
S
L
G
H
L
S
N
V
E
F
V
G
F
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
D
P
H
F
E
A
V
F
L
T
P
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
L
K
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
H
Q
Q
G
W
23
PsiBlast_CBE
89.76
99%
-144
- C1 -
-
5H16
1
COAD_ACIBS
D:
[3-163]
--
K
T
R
V
I
Y
P
G
T
F
D
P
I
T
N
G
H
V
D
L
V
T
R
A
S
R
M
F
D
E
V
V
V
A
I
A
I
G
H
H
K
N
P
L
F
S
L
E
E
R
V
A
L
A
Q
S
S
L
G
H
L
S
N
V
E
F
V
G
F
D
G
L
L
V
N
F
F
K
E
Q
K
A
T
A
V
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
D
P
H
F
E
A
V
F
L
T
P
S
E
Q
Y
S
F
I
S
S
T
L
I
R
E
I
A
R
L
K
G
D
V
T
K
F
V
P
Q
A
V
V
E
A
F
E
R
K
H
Q
Q
G
W
32
PsiBlast_CBE
78.42
67%
-159
- C1 -
-
5TS2
2
COAD_PSEA8
E:
[12-166]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
3
PsiBlast_PDB
77.35
67%
-158
- C1 -
-
5TS2
2
COAD_PSEA8
A:
[12-166]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
31
PsiBlast_CBE
77.09
67%
-161
- C1 -
-
5TS2
2
COAD_PSEA8
F:
[12-166]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
132
Fugue
76.37
59%
-148
- C1 -
-
1B6T
-
COAD_ECOLI
A:
[3-159]
---
K
R
A
I
Y
P
G
T
F
D
P
I
T
N
G
H
I
D
I
V
T
R
A
T
Q
M
F
D
H
V
I
L
A
I
A
A
S
P
S
K
K
P
M
F
T
L
E
E
R
V
A
L
A
Q
Q
A
T
A
H
L
G
N
V
E
V
V
G
F
S
D
L
M
A
N
F
A
R
N
Q
H
A
T
V
L
I
R
G
L
R
A
V
A
D
F
E
Y
E
M
Q
L
A
H
M
N
R
H
L
M
P
E
L
E
S
V
F
L
M
P
S
K
E
W
S
F
I
S
S
S
L
V
K
E
V
A
R
H
Q
G
D
V
T
H
F
L
P
E
N
V
H
Q
A
L
M
A
K
L
A
---
41
PsiBlast_CBE
75.89
67%
-154
- C1 -
-
3X1M
4
?
C:
[4-158]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
118
HHSearch
75.81
59%
-151
* C1 *
-
1GN8
1
COAD_ECOLI
B:
[1-158]
-
M
Q
K
R
A
I
Y
P
G
T
F
D
P
I
T
N
G
H
I
D
I
V
T
R
A
T
Q
M
F
D
H
V
I
L
A
I
A
A
S
P
S
K
K
P
M
F
T
L
E
E
R
V
A
L
A
Q
Q
A
T
A
H
L
G
N
V
E
V
V
G
F
S
D
L
M
A
N
F
A
R
N
Q
H
A
T
V
L
I
R
G
L
R
A
V
A
D
F
E
Y
E
M
Q
L
A
H
M
N
R
H
L
M
P
E
L
E
S
V
F
L
M
P
S
K
E
W
S
F
I
S
S
S
L
V
K
E
V
A
R
H
Q
G
D
V
T
H
F
L
P
E
N
V
H
Q
A
L
M
A
K
L
----
121
HHSearch
75.80
58%
-143
- C1 -
-
5JBN
1
COAD_ECOLI
A:
[5-164]
--
Q
K
R
A
I
Y
P
G
T
F
D
P
I
T
N
G
H
I
D
I
V
T
R
A
T
Q
M
F
D
H
V
I
L
A
I
A
A
S
P
S
K
K
P
M
F
T
L
E
E
R
V
A
L
A
Q
Q
A
T
A
H
L
G
N
V
E
V
V
G
F
S
D
L
M
A
N
F
A
R
N
Q
H
A
T
V
L
I
R
G
L
R
A
V
A
D
F
E
Y
E
M
Q
L
A
H
M
N
R
H
L
M
P
E
L
E
S
V
F
L
M
P
S
K
E
W
S
F
I
S
S
S
L
V
K
E
V
A
R
H
Q
G
D
V
T
H
F
L
P
E
N
V
H
Q
A
L
M
A
K
L
A
V
D
-
6
PsiBlast_PDB
75.78
67%
-154
- C1 -
-
3X1M
10
?
A:
[4-158]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
35
PsiBlast_CBE
75.52
67%
-164
- C1 -
-
5TS2
2
COAD_PSEA8
B:
[12-166]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
33
PsiBlast_CBE
75.11
67%
-160
- C1 -
-
5TS2
2
COAD_PSEA8
D:
[12-165]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
----
4
PsiBlast_PDB
74.83
67%
-151
- C1 -
-
3X1J
9
?
A:
[4-158]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
34
PsiBlast_CBE
74.74
67%
-160
- C1 -
-
5TS2
2
COAD_PSEA8
C:
[12-166]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
125
HHSearch
73.95
54%
-154
- C1 -
-
3K9W
3
COAD_BURP1
A:
[21-180]
-
S
M
V
V
A
V
Y
P
G
T
F
D
P
L
T
R
G
H
E
D
L
V
R
R
A
S
S
I
F
D
T
L
V
V
G
V
A
D
S
R
A
K
K
P
F
F
S
L
E
E
R
L
K
I
A
N
E
V
L
G
H
Y
P
N
V
K
V
M
G
F
T
G
L
L
K
D
F
V
R
A
N
D
A
R
V
I
V
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
M
A
G
M
N
R
Y
L
L
P
D
V
E
T
M
F
M
T
P
S
D
Q
Y
Q
F
I
S
G
T
I
V
R
E
I
A
Q
L
G
G
D
V
S
K
F
V
F
P
S
V
E
K
W
L
T
E
K
V
A
A
--
46
PsiBlast_CBE
73.87
67%
-155
- C1 -
-
3X1K
12
?
C:
[4-158]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
48
PsiBlast_CBE
73.64
67%
-150
- C1 -
-
3X1J
4
?
C:
[4-158]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
45
PsiBlast_CBE
73.26
67%
-158
- C1 -
-
3X1K
3
?
D:
[4-158]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
47
PsiBlast_CBE
73.21
67%
-155
- C1 -
-
3X1K
14
?
B:
[4-158]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
123
HHSearch
72.82
66%
-142
- C1 -
-
4RUK
19
?
F:
[1-158]
--
M
N
R
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
43
PsiBlast_CBE
72.67
67%
-158
- C1 -
-
3X1K
6
?
F:
[4-158]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
42
PsiBlast_CBE
72.61
67%
-145
- C1 -
-
3X1M
4
?
B:
[4-158]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
52
PsiBlast_CBE
71.92
61%
-155
- C1 -
-
1B6T
1
COAD_ECOLI
B:
[6-157]
------
I
Y
P
G
T
F
D
P
I
T
N
G
H
I
D
I
V
T
R
A
T
Q
M
F
D
H
V
I
L
A
I
A
A
S
P
S
K
K
P
M
F
T
L
E
E
R
V
A
L
A
Q
Q
A
T
A
H
L
G
N
V
E
V
V
G
F
S
D
L
M
A
N
F
A
R
N
Q
H
A
T
V
L
I
R
G
L
R
A
V
A
D
F
E
Y
E
M
Q
L
A
H
M
N
R
H
L
M
P
E
L
E
S
V
F
L
M
P
S
K
E
W
S
F
I
S
S
S
L
V
K
E
V
A
R
H
Q
G
D
V
T
H
F
L
P
E
N
V
H
Q
A
L
M
A
K
-----
7
PsiBlast_PDB
71.88
67%
-155
- C1 -
-
4RUK
8
?
A:
[4-158]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
49
PsiBlast_CBE
71.79
67%
-151
- C1 -
-
3X1J
5
?
B:
[4-158]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
50
PsiBlast_CBE
71.74
61%
-161
- C1 -
-
1H1T
1
COAD_ECOLI
B:
[6-157]
------
I
Y
P
G
T
F
D
P
I
T
N
G
H
I
D
I
V
T
R
A
T
Q
M
F
D
H
V
I
L
A
I
A
A
S
P
S
K
K
P
M
F
T
L
E
E
R
V
A
L
A
Q
Q
A
T
A
H
L
G
N
V
E
V
V
G
F
S
D
L
M
A
N
F
A
R
N
Q
H
A
T
V
L
I
R
G
L
R
A
V
A
D
F
E
Y
E
M
Q
L
A
H
M
N
R
H
L
M
P
E
L
E
S
V
F
L
M
P
S
K
E
W
S
F
I
S
S
S
L
V
K
E
V
A
R
H
Q
G
D
V
T
H
F
L
P
E
N
V
H
Q
A
L
M
A
K
-----
54
PsiBlast_CBE
71.46
61%
-158
- C1 -
-
1QJC
1
COAD_ECOLI
B:
[5-156]
------
I
Y
P
G
T
F
D
P
I
T
N
G
H
I
D
I
V
T
R
A
T
Q
M
F
D
H
V
I
L
A
I
A
A
S
P
S
K
K
P
M
F
T
L
E
E
R
V
A
L
A
Q
Q
A
T
A
H
L
G
N
V
E
V
V
G
F
S
D
L
M
A
N
F
A
R
N
Q
H
A
T
V
L
I
R
G
L
R
A
V
A
D
F
E
Y
E
M
Q
L
A
H
M
N
R
H
L
M
P
E
L
E
S
V
F
L
M
P
S
K
E
W
S
F
I
S
S
S
L
V
K
E
V
A
R
H
Q
G
D
V
T
H
F
L
P
E
N
V
H
Q
A
L
M
A
K
-----
114
HHSearch
71.09
54%
-153
- C1 -
-
3PXU
3
COAD_BURP1
A:
[4-163]
-
S
M
V
V
A
V
Y
P
G
T
F
D
P
L
T
R
G
H
E
D
L
V
R
R
A
S
S
I
F
D
T
L
V
V
G
V
A
D
S
R
A
K
K
P
F
F
S
L
E
E
R
L
K
I
A
N
E
V
L
G
H
Y
P
N
V
K
V
M
G
F
T
G
L
L
K
D
F
V
R
A
N
D
A
R
V
I
V
R
G
L
R
A
---
F
E
Y
E
F
Q
M
A
G
M
N
R
Y
L
L
P
D
V
E
T
M
F
M
T
P
S
D
Q
Y
Q
F
I
S
G
T
I
V
R
E
I
A
Q
L
G
G
D
V
S
K
F
V
F
P
S
V
E
K
W
L
T
E
K
V
A
A
--
51
PsiBlast_CBE
70.73
61%
-160
- C1 -
-
1GN8
1
COAD_ECOLI
B:
[6-157]
------
I
Y
P
G
T
F
D
P
I
T
N
G
H
I
D
I
V
T
R
A
T
Q
M
F
D
H
V
I
L
A
I
A
A
S
P
S
K
K
P
M
F
T
L
E
E
R
V
A
L
A
Q
Q
A
T
A
H
L
G
N
V
E
V
V
G
F
S
D
L
M
A
N
F
A
R
N
Q
H
A
T
V
L
I
R
G
L
R
A
V
A
D
F
E
Y
E
M
Q
L
A
H
M
N
R
H
L
M
P
E
L
E
S
V
F
L
M
P
S
K
E
W
S
F
I
S
S
S
L
V
K
E
V
A
R
H
Q
G
D
V
T
H
F
L
P
E
N
V
H
Q
A
L
M
A
K
-----
127
HHSearch
70.68
43%
-151
- C1 -
-
4NAH
3
COAD_STAAW
B:
[1-159]
M
E
H
T
I
A
V
I
P
G
S
F
D
P
I
T
Y
G
H
L
D
I
I
E
R
S
T
D
R
F
D
E
I
H
V
C
V
L
K
N
S
K
K
E
G
T
F
S
L
E
E
R
M
D
L
I
E
Q
S
V
K
H
L
P
N
V
K
V
H
Q
F
S
G
L
L
V
D
Y
C
E
Q
V
G
A
K
T
I
I
R
G
L
R
A
V
S
D
F
E
Y
E
L
R
L
T
S
M
N
K
K
L
N
N
E
I
E
T
L
Y
M
M
S
S
T
N
Y
S
F
I
S
S
S
I
V
K
E
V
A
A
Y
R
A
D
I
S
E
F
V
P
P
Y
V
E
K
A
L
K
K
K
F
----
36
PsiBlast_CBE
70.48
67%
-152
- C1 -
-
4RUK
19
?
F:
[4-158]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
37
PsiBlast_CBE
69.93
67%
-148
- C1 -
-
4RUK
2
?
E:
[4-158]
-----
V
L
Y
P
G
T
F
D
P
I
T
K
G
H
G
D
L
I
E
R
A
S
R
L
F
D
H
V
I
I
A
V
A
A
S
P
K
K
N
P
L
F
S
L
E
Q
R
V
A
L
A
Q
E
V
T
K
H
L
P
N
V
E
V
V
G
F
S
T
L
L
A
H
F
V
K
E
Q
K
A
N
V
F
L
R
G
L
R
A
V
S
D
F
E
Y
E
F
Q
L
A
N
M
N
R
Q
L
A
P
D
V
E
S
M
F
L
T
P
S
E
K
Y
S
F
I
S
S
T
L
V
R
E
I
A
A
L
G
G
D
I
S
K
F
V
H
P
A
V
A
D
A
L
A
E
R
F
K
---
65
PsiBlast_CBE
69.35
43%
-150
- C1 -
-
4NAH
3
COAD_STAAW
B:
[1-158]
M
E
H
T
I
A
V
I
P
G
S
F
D
P
I
T
Y
G
H
L
D
I
I
E
R
S
T
D
R
F
D
E
I
H
V
C
V
L
K
N
S
K
K
E
G
T
F
S
L
E
E
R
M
D
L
I
E
Q
S
V
K
H
L
P
N
V
K
V
H
Q
F
S
G
L
L
V
D
Y
C
E
Q
V
G
A
K
T
I
I
R
G
L
R
A
V
S
D
F
E
Y
E
L
R
L
T
S
M
N
K
K
L
N
N
E
I
E
T
L
Y
M
M
S
S
T
N
Y
S
F
I
S
S
S
I
V
K
E
V
A
A
Y
R
A
D
I
S
E
F
V
P
P
Y
V
E
K
A
L
K
K
K
-----
122
HHSearch
68.40
51%
-150
- C1 -
-
1OD6
1
COAD_THET8
A:
[2-160]
----
H
V
V
Y
P
G
S
F
D
P
L
T
N
G
H
L
D
V
I
Q
R
A
S
R
L
F
E
K
V
T
V
A
V
L
E
N
---
Q
Y
L
F
S
A
E
E
R
L
A
I
I
R
E
A
T
A
H
L
A
N
V
E
A
A
T
F
S
G
L
L
V
D
F
V
R
R
V
G
A
Q
A
I
V
K
G
L
R
A
V
S
D
Y
E
Y
E
L
Q
M
A
H
L
N
R
Q
L
Y
P
G
L
E
T
L
F
I
L
A
A
T
R
Y
S
F
V
S
S
T
M
V
K
E
I
A
R
Y
G
G
D
V
S
K
L
V
P
P
A
T
L
R
A
L
K
A
K
L
G
Q
--
62
PsiBlast_CBE
67.51
43%
-142
- C1 -
-
4NAH
3
COAD_STAAW
E:
[1-158]
M
E
H
T
I
A
V
I
P
G
S
F
D
P
I
T
Y
G
H
L
D
I
I
E
R
S
T
D
R
F
D
E
I
H
V
C
V
L
K
N
S
K
K
E
G
T
F
S
L
E
E
R
M
D
L
I
E
Q
S
V
K
H
L
P
N
V
K
V
H
Q
F
S
G
L
L
V
D
Y
C
E
Q
V
G
A
K
T
I
I
R
G
L
R
A
V
S
D
F
E
Y
E
L
R
L
T
S
M
N
K
K
L
N
N
E
I
E
T
L
Y
M
M
S
S
T
N
Y
S
F
I
S
S
S
I
V
K
E
V
A
A
Y
R
A
D
I
S
E
F
V
P
P
Y
V
E
K
A
L
K
K
K
-----
58
PsiBlast_CBE
66.71
43%
-150
- C1 -
-
4NAT
3
COAD_STAAW
C:
[1-158]
M
E
H
T
I
A
V
I
P
G
S
F
D
P
I
T
Y
G
H
L
D
I
I
E
R
S
T
D
R
F
D
E
I
H
V
C
V
L
K
-----
G
T
F
S
L
E
E
R
M
D
L
I
E
Q
S
V
K
H
L
P
N
V
K
V
H
Q
F
S
G
L
L
V
D
Y
C
E
Q
V
G
A
K
T
I
I
R
G
L
R
A
V
S
D
F
E
Y
E
L
R
L
T
S
M
N
K
K
L
N
N
E
I
E
T
L
Y
M
M
S
S
T
N
Y
S
F
I
S
S
S
I
V
K
E
V
A
A
Y
R
A
D
I
S
E
F
V
P
P
Y
V
E
K
A
L
K
K
K
-----
63
PsiBlast_CBE
66.70
43%
-151
- C1 -
-
4NAH
3
COAD_STAAW
D:
[2-158]
-
E
H
T
I
A
V
I
P
G
S
F
D
P
I
T
Y
G
H
L
D
I
I
E
R
S
T
D
R
F
D
E
I
H
V
C
V
L
K
N
S
K
K
E
G
T
F
S
L
E
E
R
M
D
L
I
E
Q
S
V
K
H
L
P
N
V
K
V
H
Q
F
S
G
L
L
V
D
Y
C
E
Q
V
G
A
K
T
I
I
R
G
L
R
A
V
S
D
F
E
Y
E
L
R
L
T
S
M
N
K
K
L
N
N
E
I
E
T
L
Y
M
M
S
S
T
N
Y
S
F
I
S
S
S
I
V
K
E
V
A
A
Y
R
A
D
I
S
E
F
V
P
P
Y
V
E
K
A
L
K
K
K
-----
64
PsiBlast_CBE
66.56
43%
-147
- C1 -
-
4NAH
3
COAD_STAAW
C:
[1-158]
M
E
H
T
I
A
V
I
P
G
S
F
D
P
I
T
Y
G
H
L
D
I
I
E
R
S
T
D
R
F
D
E
I
H
V
C
V
L
K
N
S
K
K
E
G
T
F
S
L
E
E
R
M
D
L
I
E
Q
S
V
K
H
L
P
N
V
K
V
H
Q
F
S
G
L
L
V
D
Y
C
E
Q
V
G
A
K
T
I
I
R
G
L
R
A
V
S
D
F
E
Y
E
L
R
L
T
S
M
N
K
K
L
N
N
E
I
E
T
L
Y
M
M
S
S
T
N
Y
S
F
I
S
S
S
I
V
K
E
V
A
A
Y
R
A
D
I
S
E
F
V
P
P
Y
V
E
K
A
L
K
K
K
-----
128
HHSearch
65.21
43%
-151
- C1 -
-
4NAT
4
COAD_STAAW
A:
[2-159]
-
E
H
T
I
A
V
I
P
G
S
F
D
P
I
T
Y
G
H
L
D
I
I
E
R
S
T
D
R
F
D
E
I
H
V
C
V
L
------
G
T
F
S
L
E
E
R
M
D
L
I
E
Q
S
V
K
H
L
P
N
V
K
V
H
Q
F
S
G
L
L
V
D
Y
C
E
Q
V
G
A
K
T
I
I
R
G
L
R
A
V
S
D
F
E
Y
E
L
R
L
T
S
M
N
K
K
L
N
N
E
I
E
T
L
Y
M
M
S
S
T
N
Y
S
F
I
S
S
S
I
V
K
E
V
A
A
Y
R
A
D
I
S
E
F
V
P
P
Y
V
E
K
A
L
K
K
K
F
----
60
PsiBlast_CBE
64.59
43%
-151
- C1 -
-
4NAT
4
COAD_STAAW
A:
[2-158]
-
E
H
T
I
A
V
I
P
G
S
F
D
P
I
T
Y
G
H
L
D
I
I
E
R
S
T
D
R
F
D
E
I
H
V
C
V
L
------
G
T
F
S
L
E
E
R
M
D
L
I
E
Q
S
V
K
H
L
P
N
V
K
V
H
Q
F
S
G
L
L
V
D
Y
C
E
Q
V
G
A
K
T
I
I
R
G
L
R
A
V
S
D
F
E
Y
E
L
R
L
T
S
M
N
K
K
L
N
N
E
I
E
T
L
Y
M
M
S
S
T
N
Y
S
F
I
S
S
S
I
V
K
E
V
A
A
Y
R
A
D
I
S
E
F
V
P
P
Y
V
E
K
A
L
K
K
K
-----
55
PsiBlast_CBE
64.07
43%
-149
- C1 -
-
4NAU
1
COAD_STAAW
C:
[1-158]
M
E
H
T
I
A
V
I
P
G
S
F
D
P
I
T
Y
G
H
L
D
I
I
E
R
S
T
D
R
F
D
E
I
H
V
C
V
L
K
N
S
K
K
E
G
T
F
S
L
E
E
R
M
D
L
I
E
Q
S
V
K
H
L
P
N
V
K
V
H
Q
F
S
G
L
L
V
D
Y
C
E
Q
V
G
A
K
T
I
I
R
G
L
R
A
V
S
D
F
E
Y
E
L
R
L
T
S
M
N
K
K
L
N
N
E
I
E
T
L
Y
M
M
S
S
T
N
Y
S
F
I
S
S
S
I
V
K
E
V
A
A
Y
R
A
D
I
S
E
F
V
P
P
Y
V
E
K
A
L
K
K
K
-----
59
PsiBlast_CBE
63.02
43%
-150
- C1 -
-
4NAT
5
COAD_STAAW
B:
[1-158]
M
E
H
T
I
A
V
I
P
G
S
F
D
P
I
T
Y
G
H
L
D
I
I
E
R
S
T
D
R
F
D
E
I
H
V
C
V
L
K
----
E
G
T
F
S
L
E
E
R
M
D
L
I
E
Q
S
V
K
H
L
P
N
V
K
V
H
Q
F
S
G
L
L
V
D
Y
C
E
Q
V
G
A
K
T
I
I
R
G
L
R
A
V
S
D
F
E
Y
E
L
R
L
T
S
M
N
K
K
L
N
N
E
I
E
T
L
Y
M
M
S
S
T
N
Y
S
F
I
S
S
S
I
V
K
E
V
A
A
Y
R
A
D
I
S
E
F
V
P
P
Y
V
E
K
A
L
K
K
K
-----
73
PsiBlast_CBE
62.12
46%
-149
- C1 -
-
3OTW
2
COAD_HELPY
E:
[12-156]
------
I
Y
P
G
T
F
D
P
V
T
N
G
H
I
D
I
I
H
R
S
S
E
L
F
E
K
L
I
V
A
V
A
H
S
S
A
K
N
P
M
F
S
L
D
E
R
L
K
M
I
Q
L
A
T
K
S
F
K
N
V
E
C
V
A
F
E
G
L
L
A
N
L
A
K
E
Y
H
C
K
V
L
V
R
G
L
R
V
V
S
D
F
E
Y
E
L
Q
M
G
Y
A
N
K
S
L
N
H
E
L
E
T
L
Y
F
M
P
T
L
Q
N
A
F
I
S
S
S
I
V
R
S
I
I
A
H
K
G
D
A
S
H
L
V
P
K
E
I
------------
72
PsiBlast_CBE
61.42
46%
-150
- C1 -
-
3OTW
2
COAD_HELPY
F:
[12-156]
------
I
Y
P
G
T
F
D
P
V
T
N
G
H
I
D
I
I
H
R
S
S
E
L
F
E
K
L
I
V
A
V
A
H
S
S
A
K
N
P
M
F
S
L
D
E
R
L
K
M
I
Q
L
A
T
K
S
F
K
N
V
E
C
V
A
F
E
G
L
L
A
N
L
A
K
E
Y
H
C
K
V
L
V
R
G
L
R
V
V
S
D
F
E
Y
E
L
Q
M
G
Y
A
N
K
S
L
N
H
E
L
E
T
L
Y
F
M
P
T
L
Q
N
A
F
I
S
S
S
I
V
R
S
I
I
A
H
K
G
D
A
S
H
L
V
P
K
E
I
------------
74
PsiBlast_CBE
61.41
46%
-153
- C1 -
-
3OTW
2
COAD_HELPY
D:
[12-156]
------
I
Y
P
G
T
F
D
P
V
T
N
G
H
I
D
I
I
H
R
S
S
E
L
F
E
K
L
I
V
A
V
A
H
S
S
A
K
N
P
M
F
S
L
D
E
R
L
K
M
I
Q
L
A
T
K
S
F
K
N
V
E
C
V
A
F
E
G
L
L
A
N
L
A
K
E
Y
H
C
K
V
L
V
R
G
L
R
V
V
S
D
F
E
Y
E
L
Q
M
G
Y
A
N
K
S
L
N
H
E
L
E
T
L
Y
F
M
P
T
L
Q
N
A
F
I
S
S
S
I
V
R
S
I
I
A
H
K
G
D
A
S
H
L
V
P
K
E
I
------------
77
PsiBlast_CBE
60.97
46%
-157
- C1 -
-
3OTW
2
COAD_HELPY
A:
[12-156]
------
I
Y
P
G
T
F
D
P
V
T
N
G
H
I
D
I
I
H
R
S
S
E
L
F
E
K
L
I
V
A
V
A
H
S
S
A
K
N
P
M
F
S
L
D
E
R
L
K
M
I
Q
L
A
T
K
S
F
K
N
V
E
C
V
A
F
E
G
L
L
A
N
L
A
K
E
Y
H
C
K
V
L
V
R
G
L
R
V
V
S
D
F
E
Y
E
L
Q
M
G
Y
A
N
K
S
L
N
H
E
L
E
T
L
Y
F
M
P
T
L
Q
N
A
F
I
S
S
S
I
V
R
S
I
I
A
H
K
G
D
A
S
H
L
V
P
K
E
I
------------
75
PsiBlast_CBE
60.22
46%
-151
- C1 -
-
3OTW
2
COAD_HELPY
C:
[12-156]
------
I
Y
P
G
T
F
D
P
V
T
N
G
H
I
D
I
I
H
R
S
S
E
L
F
E
K
L
I
V
A
V
A
H
S
S
A
K
N
P
M
F
S
L
D
E
R
L
K
M
I
Q
L
A
T
K
S
F
K
N
V
E
C
V
A
F
E
G
L
L
A
N
L
A
K
E
Y
H
C
K
V
L
V
R
G
L
R
V
V
S
D
F
E
Y
E
L
Q
M
G
Y
A
N
K
S
L
N
H
E
L
E
T
L
Y
F
M
P
T
L
Q
N
A
F
I
S
S
S
I
V
R
S
I
I
A
H
K
G
D
A
S
H
L
V
P
K
E
I
------------
76
PsiBlast_CBE
60.02
46%
-154
- C1 -
-
3OTW
2
COAD_HELPY
B:
[12-156]
------
I
Y
P
G
T
F
D
P
V
T
N
G
H
I
D
I
I
H
R
S
S
E
L
F
E
K
L
I
V
A
V
A
H
S
S
A
K
N
P
M
F
S
L
D
E
R
L
K
M
I
Q
L
A
T
K
S
F
K
N
V
E
C
V
A
F
E
G
L
L
A
N
L
A
K
E
Y
H
C
K
V
L
V
R
G
L
R
V
V
S
D
F
E
Y
E
L
Q
M
G
Y
A
N
K
S
L
N
H
E
L
E
T
L
Y
F
M
P
T
L
Q
N
A
F
I
S
S
S
I
V
R
S
I
I
A
H
K
G
D
A
S
H
L
V
P
K
E
I
------------
79
PsiBlast_CBE
52.71
45%
-205
- C1 -
-
3NV7
1
COAD_HELPY
A:
[6-150]
------
I
Y
P
G
T
F
D
P
V
T
N
G
H
I
D
I
I
H
R
S
S
E
L
F
E
K
L
I
V
A
V
A
H
S
S
A
K
N
P
M
F
S
L
D
E
R
L
K
M
I
Q
L
A
T
K
S
F
K
N
V
E
C
V
A
F
E
G
L
L
A
Y
L
A
K
E
Y
H
C
K
V
L
V
R
G
L
R
V
V
S
D
F
E
Y
E
L
Q
M
G
Y
A
N
K
S
L
N
H
E
L
E
T
L
Y
F
M
P
T
L
Q
N
A
F
I
S
S
S
I
V
R
S
I
I
A
H
K
G
D
A
S
H
L
V
P
K
E
I
------------
126
HHSearch
52.37
42%
-190
- C1 -
-
3NV7
1
COAD_HELPY
A:
[3-157]
---
K
V
G
I
Y
P
G
T
F
D
P
V
T
N
G
H
I
D
I
I
H
R
S
S
E
L
F
E
K
L
I
V
A
V
A
H
S
S
A
K
N
P
M
F
S
L
D
E
R
L
K
M
I
Q
L
A
T
K
S
F
K
N
V
E
C
V
A
F
E
G
L
L
A
Y
L
A
K
E
Y
H
C
K
V
L
V
R
G
L
R
V
V
S
D
F
E
Y
E
L
Q
M
G
Y
A
N
K
S
L
N
H
E
L
E
T
L
Y
F
M
P
T
L
Q
N
A
F
I
S
S
S
I
V
R
S
I
I
A
H
K
G
D
A
S
H
L
V
P
K
E
I
Y
P
L
I
S
K
A
-----