@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VTY0: (2017-12-15 )
MRPTVLCFSGLDPSGGAGLQADIEAIGQSGAHAAIACTALTIQNSQQVFGSEATSKELLLAQANAVVGDLPIKCVKSGMLGTTDNIAALAEFLRAHPDYQYVLDPVLVANSGGSLGDQATLVKAFVELILLATLITPNTVELRALTGVTDLDQATQKLFEMGAKAVLVKGGHEDTPDFIKNSLYIDGELAASSTCPRLEGEYHGSGCSLASFIAGRLALGDSLKIAVQHAETWLFGVLKNAETPVPNGQKIPKRF
Atome Classification :
(20 SA)
-.........10........20........30........40...-----.....50-..--.....--..60......-.--.70........80........90....---.--...100.......110.-..--.--...120.......130........140.....------.----.--------150.---...--...160........170---.---....-.-..180.....----.-.190.......-200.-.......210.......220.......230.......240...-....250...-----
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-MR
P
T
V
L
C
FSGLDPSGGAG
L
Q
A
D
I
E
A
IGQSGA
H
A
A
I
A
C
T
A
L
T
IQN-----
S
Q
Q
VFG--SE--ATSK
E
--
L
L
L
A
QANAVV-G--DL
P
I
K
C
V
KSGMLGTT
D
N
I
A
A
L
A
E
F
L
R
A---H--PD
Y
Q
Y
VL
D
P
V
L
V
ANSGG-SL--G--
D
Q
A
T
L
V
K
A
F
V
E
L
I
L
-
L
A
T
LITPN
T
V
E
L
R
A
LTG------V----
T
--------
D
L
D
Q
---
A
T
Q
--
K
L
F
E-MGA
K
A
V
L
V
KGG----H---ED
T
P
-
D
-
F
I
KN
S
L
Y
I
DG----E-LAASSTCPRLE-GE-Y-HGSG
C
S
L
A
S
F
I
A
G
R
L
ALGDS
L
K
I
A
V
Q
H
A
E
T
W
L
F
G
V
L
KNAETPV-PNGQKIPKRF-----
1
PsiBlast_PDB
98.03
98%
-115
- C4 -
-
4YL5
2
?
A:
[9-245]
-
V
R
P
T
V
L
C
F
S
G
L
D
P
S
G
G
A
G
L
Q
A
D
I
E
A
I
G
Q
S
G
A
H
A
A
I
A
C
T
A
L
T
I
Q
N
-----
S
Q
Q
V
F
G
--
F
E
--
A
T
S
K
E
--
L
L
L
A
Q
A
N
A
V
V
-
G
--
D
L
P
I
K
C
V
K
S
G
M
L
G
T
T
D
N
I
A
A
L
A
E
F
L
R
A
---
H
--
P
D
Y
Q
Y
V
L
D
P
V
L
V
A
N
S
G
G
-
S
L
--
G
--
D
Q
A
T
L
V
K
A
F
V
E
L
I
P
-
L
A
T
L
I
T
P
N
T
V
E
L
R
A
L
T
G
------
V
----
T
--------
D
L
D
Q
---
A
T
Q
--
K
L
F
E
-
M
G
A
K
A
V
L
V
K
G
G
----
H
---
E
D
T
P
-
D
-
F
I
K
N
S
L
Y
I
D
G
----
E
-
L
A
A
S
S
T
C
P
-------------
C
S
L
A
S
F
I
A
G
R
L
A
L
G
D
S
L
K
I
A
V
Q
H
A
E
T
W
L
F
G
V
------------------------
2
PsiBlast_PDB
96.29
98%
-112
- C4 -
-
4YWR
1
?
A:
[10-246]
--
R
P
T
V
L
C
F
S
G
L
D
P
S
G
G
A
G
L
Q
A
D
I
E
A
I
G
Q
S
G
A
H
A
A
I
A
C
T
A
L
T
I
Q
N
-----
S
Q
Q
V
F
G
--
F
E
--
A
T
S
K
E
--
L
L
L
A
Q
A
N
A
V
V
-
G
--
D
L
P
I
K
C
V
K
S
G
M
L
G
T
T
D
N
I
A
A
L
A
E
F
L
R
A
---
H
--
P
D
Y
Q
Y
V
L
D
P
V
L
V
A
N
S
G
G
-
S
L
--
G
--
D
Q
A
T
L
V
K
A
F
V
E
L
I
P
-
L
A
T
L
I
T
P
N
T
V
E
L
R
A
L
T
G
------
V
----
T
--------
D
L
D
Q
---
A
T
Q
--
K
L
F
E
-
M
G
A
K
A
V
L
V
K
G
G
----
H
---
E
D
T
P
-
D
-
F
I
K
N
S
L
Y
I
D
G
----
E
-
L
A
A
S
S
T
C
P
R
------------
C
S
L
A
S
F
I
A
G
R
L
A
L
G
D
S
L
K
I
A
V
Q
H
A
E
T
W
L
F
G
V
L
-----------------------
70
HHSearch
91.39
98%
-76
- C4 -
-
4YWR
1
?
A:
[10-246]
--
R
P
T
V
L
C
F
S
G
L
D
P
S
G
G
A
G
L
Q
A
D
I
E
A
I
G
Q
S
G
A
H
A
A
I
A
C
T
A
L
T
I
Q
N
-----
S
Q
Q
V
F
G
--
F
E
--
A
T
S
K
E
--
L
L
L
A
Q
A
N
A
V
V
-
G
--
D
L
P
I
K
C
V
K
S
G
M
L
G
T
T
D
N
I
A
A
L
A
E
F
L
R
A
---
H
--
P
D
Y
Q
Y
V
L
D
P
V
L
V
A
N
S
G
G
-
S
L
--
G
--
D
Q
A
T
L
V
K
A
F
V
E
-
L
I
P
L
A
T
L
I
T
P
N
T
V
E
L
R
A
L
T
G
------
V
----
T
--------
D
L
D
Q
---
A
T
Q
--
K
L
F
E
-
M
G
A
K
A
V
L
V
K
G
G
----
H
---
E
D
T
P
-
D
-
F
I
K
N
S
L
Y
I
D
G
----
E
-
L
A
A
S
S
T
C
P
R
------------
C
S
L
A
S
F
I
A
G
R
L
A
L
G
D
S
L
K
I
A
V
Q
H
A
E
T
W
L
F
G
V
L
-----------------------
74
HHSearch
68.25
32%
-66
- C4 -
-
1JXI
1
THID_SALTY
B:
[25-283]
--
R
I
N
A
L
T
I
A
G
T
D
P
S
G
G
A
G
I
Q
A
D
L
K
T
F
S
A
L
G
A
Y
G
C
S
V
I
T
A
L
V
A
E
N
-----
T
C
G
V
Q
S
--
V
Y
--
R
I
E
P
D
--
F
V
A
A
Q
L
D
S
V
F
-
S
--
D
V
R
I
D
T
T
K
I
G
M
L
A
E
T
D
I
V
E
A
V
A
E
R
L
Q
R
---
H
--
H
V
R
N
V
V
L
D
T
V
M
L
A
K
S
G
D
-
P
L
--
L
--
S
-
P
S
A
I
E
T
L
R
V
R
L
L
P
Q
V
S
L
I
T
P
N
L
P
E
A
A
A
L
L
D
------
A
----
P
HARTEQ--
E
M
L
A
---
Q
G
R
--
A
L
L
A
-
M
G
C
E
A
V
L
M
K
G
-------------------
D
W
L
F
T
R
E
------
G
E
Q
R
F
---
R
V
N
T
K
N
-
T
-
H
G
T
G
C
T
L
S
A
A
L
A
A
L
R
P
R
H
R
S
W
G
E
T
V
N
E
A
K
A
W
L
S
A
A
L
A
Q
A
D
T
L
E
V
G
K
G
I
G
P
V
H
H
------
5
PsiBlast_PDB
67.55
35%
-69
- C4 -
-
1JXI
1
THID_SALTY
A:
[25-271]
--
R
I
N
A
L
T
I
A
G
T
D
P
S
G
G
A
G
I
Q
A
D
L
K
T
F
S
A
L
G
A
Y
G
C
S
V
I
T
A
L
V
A
E
N
-----
T
C
G
V
Q
S
--
V
Y
--
R
I
E
P
D
--
F
V
A
A
Q
L
D
S
V
F
-
S
--
D
V
R
I
D
T
T
K
I
G
M
L
A
E
T
D
I
V
E
A
V
A
E
R
L
Q
R
---
H
--
H
V
R
N
V
V
L
D
T
V
M
L
A
K
S
G
D
-
P
L
--
L
--
S
P
S
A
I
E
T
L
R
V
R
L
L
P
-
Q
V
S
L
I
T
P
N
L
P
E
A
A
A
L
L
D
------
A
PHAR
T
--------
E
Q
E
M
---
L
A
Q
G
R
A
L
L
A
-
M
G
C
E
A
V
L
M
K
G
--------------
D
-
W
L
---
F
T
R
E
G
----
E
-
Q
R
F
-----
R
V
N
-
T
K
N
T
-
H
G
T
G
C
T
L
S
A
A
L
A
A
L
R
P
R
H
R
S
W
G
E
T
V
N
E
A
K
A
W
L
S
A
A
L
A
Q
A
D
T
------------------
75
HHSearch
67.48
32%
-72
- C4 -
-
1JXH
-
THID_SALTY
A:
[25-283]
--
R
I
N
A
L
T
I
A
G
T
D
P
S
G
G
A
G
I
Q
A
D
L
K
T
F
S
A
L
G
A
Y
G
C
S
V
I
T
A
L
V
A
E
N
-----
T
C
G
V
Q
S
--
V
Y
--
R
I
E
P
D
--
F
V
A
A
Q
L
D
S
V
F
-
S
--
D
V
R
I
D
T
T
K
I
G
M
L
A
E
T
D
I
V
E
A
V
A
E
R
L
Q
R
---
H
--
H
V
R
N
V
V
L
D
T
V
M
L
-------
L
--
L
--
S
-
P
S
A
I
E
T
L
R
V
R
L
L
P
Q
V
S
L
I
T
P
N
L
P
E
A
A
A
L
L
D
------
A
----
P
HART
E
Q
--
E
M
L
A
---
Q
G
R
--
A
L
L
A
-
M
G
C
E
A
V
L
M
K
G
-------------------
D
W
L
F
T
R
E
------
G
E
Q
R
F
---
R
V
N
T
K
N
-
T
-
H
G
T
G
C
T
L
S
A
A
L
A
A
L
R
P
R
H
R
S
W
G
E
T
V
N
E
A
K
A
W
L
S
A
A
L
A
Q
A
D
T
L
E
V
G
K
G
I
G
P
V
H
H
------
22
PsiBlast_CBE
67.13
35%
-70
- C4 -
-
1JXI
1
THID_SALTY
B:
[25-271]
--
R
I
N
A
L
T
I
A
G
T
D
P
S
G
G
A
G
I
Q
A
D
L
K
T
F
S
A
L
G
A
Y
G
C
S
V
I
T
A
L
V
A
E
N
-----
T
C
G
V
Q
S
--
V
Y
--
R
I
E
P
D
--
F
V
A
A
Q
L
D
S
V
F
-
S
--
D
V
R
I
D
T
T
K
I
G
M
L
A
E
T
D
I
V
E
A
V
A
E
R
L
Q
R
---
H
--
H
V
R
N
V
V
L
D
T
V
M
L
A
K
S
G
D
-
P
L
--
L
--
S
P
S
A
I
E
T
L
R
V
R
L
L
P
-
Q
V
S
L
I
T
P
N
L
P
E
A
A
A
L
L
D
------
A
PHAR
T
--------
E
Q
E
M
---
L
A
Q
GR
A
L
L
A
-
M
G
C
E
A
V
L
M
K
G
--------------
D
-
W
L
---
F
T
R
E
G
----
E
-
Q
R
F
-----
R
V
N
-
T
K
N
T
-
H
G
T
G
C
T
L
S
A
A
L
A
A
L
R
P
R
H
R
S
W
G
E
T
V
N
E
A
K
A
W
L
S
A
A
L
A
Q
A
D
T
------------------
4
PsiBlast_PDB
65.86
35%
-78
- C4 -
-
1JXH
-
THID_SALTY
A:
[25-271]
--
R
I
N
A
L
T
I
A
G
T
D
P
S
G
G
A
G
I
Q
A
D
L
K
T
F
S
A
L
G
A
Y
G
C
S
V
I
T
A
L
V
A
E
N
-----
T
C
G
V
Q
S
--
V
Y
--
R
I
E
P
D
--
F
V
A
A
Q
L
D
S
V
F
-
S
--
D
V
R
I
D
T
T
K
I
G
M
L
A
E
T
D
I
V
E
A
V
A
E
R
L
Q
R
---
H
--
H
V
R
N
V
V
L
D
T
V
M
L
-------
L
--
L
--
S
P
S
A
I
E
T
L
R
V
R
L
L
P
-
Q
V
S
L
I
T
P
N
L
P
E
A
A
A
L
L
D
------
A
PHAR
T
--------
E
Q
E
M
---
L
A
Q
G
R
A
L
L
A
-
M
G
C
E
A
V
L
M
K
G
--------------
D
-
W
L
---
F
T
R
E
G
----
E
-
Q
R
F
-----
R
V
N
-
T
K
N
T
-
H
G
T
G
C
T
L
S
A
A
L
A
A
L
R
P
R
H
R
S
W
G
E
T
V
N
E
A
K
A
W
L
S
A
A
L
A
Q
A
D
T
------------------
61
HHSearch
63.60
34%
-52
* C4 *
-
1UB0
6
?
A:
[1-257]
--
M
R
V
A
L
T
I
A
G
S
D
S
G
G
G
A
G
V
Q
A
D
L
K
V
F
F
R
F
G
V
Y
G
T
S
A
L
T
L
V
T
A
Q
N
-----
T
L
G
V
Q
R
--
V
H
--
L
L
P
P
E
--
V
V
Y
A
Q
I
E
S
V
A
-
Q
--
D
F
P
L
H
A
A
K
T
G
A
L
G
D
A
A
I
V
E
A
V
A
E
A
V
R
R
---
F
--
G
V
R
P
L
V
V
D
P
V
M
--------------
A
-
K
E
A
A
A
A
L
K
E
R
L
F
P
L
A
D
L
V
T
P
N
R
L
E
A
E
A
L
L
G
------
R
----
P
I
R
T
L
K
---
E
A
E
E
---
A
A
K
--
A
L
L
A
-
L
G
P
K
A
V
L
L
K
G
G
----
H
---
L
------
E
A
V
D
L
L
A
T
R
G
------
G
V
L
R
F
S
A
P
R
V
H
T
R
N
-
T
-
H
G
T
G
C
T
L
S
A
A
I
A
A
L
L
A
K
G
R
P
L
A
E
A
V
A
E
A
K
A
Y
L
T
R
A
L
K
T
A
P
S
L
--
G
H
G
H
G
P
L
D
H
W
-----
81
HHSearch
62.14
33%
-56
- C4 -
-
3RM5
-
THI20_YEAST
A:
[22-291]
--
L
P
T
V
L
S
I
A
G
T
D
P
S
G
G
A
G
I
E
A
D
V
K
T
I
T
A
H
R
C
Y
A
M
T
C
I
T
A
L
N
A
Q
T
-----
P
V
K
V
Y
S
--
I
N
--
N
T
P
K
E
--
V
V
F
Q
T
L
E
S
N
L
-
K
--
D
M
K
C
N
V
I
K
T
G
M
L
T
A
A
-
A
I
E
V
L
H
E
K
L
L
Q
---
L
GE
N
R
P
K
L
V
V
D
P
V
L
--------------
G
-
K
D
I
V
S
L
I
T
E
K
V
A
P
F
A
D
I
L
T
P
N
I
P
E
C
Y
K
L
L
G
------
E
----
E
R
K
V
NGL
Q
-
D
I
F
Q
---
I
A
K
--
D
L
A
K
I
T
K
C
S
N
I
L
V
K
G
G
----
H
-------E
K
-
Y
I
T
D
V
L
F
L
G
A
----
E
Q
K
F
I
I
F
K
G
N
F
V
N
T
T
H
-
T
-
H
G
T
G
C
T
L
A
S
A
I
A
S
N
L
A
R
G
Y
S
L
P
Q
S
V
Y
G
G
I
E
Y
V
Q
N
A
V
A
I
G
C
D
------------------
3
PsiBlast_PDB
61.96
32%
-64
- C4 -
-
4JJP
-
?
A:
[10-248]
---
P
T
-
L
T
I
A
G
S
D
S
S
G
G
A
G
I
Q
A
D
L
K
T
F
S
A
I
G
T
Y
G
M
S
V
I
T
A
I
T
A
Q
N
-----
T
K
G
V
F
A
--
V
E
--
D
L
N
K
K
--
I
I
K
K
Q
I
E
A
V
F
-
E
--
D
I
P
P
R
A
V
K
I
G
M
V
S
S
P
E
I
I
L
E
I
V
E
N
L
K
K
---
Y
--
N
P
K
Y
L
V
V
D
P
V
M
I
S
K
S
G
Y
-
Y
L
--
L
--
K
P
E
A
K
E
N
L
I
K
Y
L
I
P
-
L
A
Y
I
I
T
P
N
I
P
E
A
E
E
I
T
G
IKIHN-
V
----
D
--------
D
M
K
R
---
V
G
E
--
E
I
L
Q
-
L
G
P
K
F
V
L
M
K
G
G
----
H
---
L
D
G
E
-
A
-
V
---
D
I
L
V
G
K
----
N
-
I
F
K
V
Y
K
S
E
------------
G
C
T
L
S
S
A
I
T
S
Y
L
A
L
G
Y
E
I
T
E
A
V
N
L
S
K
I
Y
I
T
E
A
I
K
----------------------
21
PsiBlast_CBE
61.80
32%
-69
- C4 -
-
4JJP
1
?
B:
[10-246]
---
P
T
-
L
T
I
A
G
S
D
S
S
G
G
A
G
I
Q
A
D
L
K
T
F
S
A
I
G
T
Y
G
M
S
V
I
T
A
I
T
A
Q
N
-----
T
K
G
V
F
A
--
V
E
--
D
L
N
K
K
--
I
I
K
K
Q
I
E
A
V
F
-
E
--
D
I
P
P
R
A
V
K
I
G
M
V
S
S
P
E
I
I
L
E
I
V
E
N
L
K
K
---
Y
--
N
P
K
Y
L
V
V
D
P
V
M
I
------
Y
L
--
L
--
K
P
E
A
K
E
N
L
I
K
Y
L
I
P
-
L
A
Y
I
I
T
P
N
I
P
E
A
E
E
I
T
G
I
K
I
H
N
-
V
----
D
--------
D
M
K
R
---
V
G
E
--
E
I
L
Q
-
L
G
P
K
F
V
L
M
K
G
G
-------------
A
-
V
---
D
I
L
V
G
K
----
N
-
I
F
K
V
Y
K
S
-------------
G
C
T
L
S
S
A
I
T
S
Y
L
A
L
G
Y
E
I
T
E
A
V
N
L
S
K
I
Y
I
T
E
A
------------------------
80
HHSearch
61.26
33%
-61
- C4 -
-
3RM5
-
THI20_YEAST
B:
[22-291]
--
L
P
T
V
L
S
I
A
G
T
D
P
S
G
G
A
G
I
E
A
D
V
K
T
I
T
A
H
R
C
Y
A
M
T
C
I
T
A
L
N
A
Q
T
-----
P
V
K
V
Y
S
--
I
N
--
N
T
P
K
E
--
V
V
F
Q
T
L
E
S
N
L
-
K
--
D
M
K
C
N
V
I
K
T
G
M
L
T
A
A
-
A
I
E
V
L
H
E
K
L
L
Q
---
L
GE
N
R
P
K
L
V
V
D
P
V
L
V
A
--------------
K
D
I
V
S
L
I
T
E
K
V
A
P
F
A
D
I
L
T
P
N
I
P
E
C
Y
K
L
L
G
------
E
----
E
R
K
VNG
L
Q
-
D
I
F
Q
---
I
A
K
--
D
L
A
K
I
T
K
C
S
N
I
L
V
K
G
G
----
H
---
I
--------
T
D
V
L
F
L
G
A
----
E
Q
K
F
I
I
F
K
G
N
F
V
N
T
T
H
-
T
-
H
G
T
G
C
T
L
A
S
A
I
A
S
N
L
A
R
G
Y
S
L
P
Q
S
V
Y
G
G
I
E
Y
V
Q
N
A
V
A
I
G
C
D
------------------
51
Fugue
60.36
31%
-25
- C4 -
-
1JXH
-
THID_SALTY
A:
[23-288]
M
Q
R
I
N
A
L
T
I
A
G
T
D
P
S
G
G
A
G
I
Q
A
D
L
K
T
F
S
A
L
G
A
Y
G
C
S
V
I
T
A
L
V
A
E
N
-----
T
C
G
V
Q
S
--
V
Y
--
R
I
E
P
D
--
F
V
A
A
Q
L
D
S
V
F
-
S
--
D
V
R
I
D
T
T
K
I
G
M
L
A
E
T
D
I
V
E
A
V
A
E
R
L
Q
R
---
H
--
H
V
R
N
V
V
L
D
T
V
M
L
-------
L
--
L
--
S
P
S
A
I
E
T
L
R
V
R
L
L
P
-
Q
V
S
L
I
T
P
N
L
P
E
A
A
A
L
L
D
APHART
E
----
Q
--------
E
M
L
A
---
Q
G
R
--
A
L
L
A
-
M
G
C
E
A
V
L
M
K
G
D
----
W
---
L
F
T
R
-
E
-
G
E
Q
R
F
------------------
R
V
N
T
-
K
N
-
T
-
H
G
T
G
C
T
L
S
A
A
L
A
A
L
R
P
R
H
R
S
W
G
E
T
V
N
E
A
K
A
W
L
S
A
A
L
A
Q
A
D
T
L
E
-
V
G
K
G
I
G
P
V
H
H
FHAWW
64
HHSearch
58.82
24%
-34
- C4 -
-
3MBH
1
?
D:
[6-260]
-
K
V
K
K
I
A
A
V
H
D
L
S
G
M
G
R
V
S
L
T
V
V
I
P
I
L
S
S
M
G
F
Q
V
C
P
L
P
T
A
V
L
S
N
H
-----
T
Q
-
Y
P
G
--
F
S
FL
D
L
T
D
E
MP
K
I
I
A
E
W
K
K
L
-----
E
V
Q
F
D
A
I
Y
T
G
Y
L
G
S
P
R
Q
I
Q
I
V
S
D
F
I
K
D
---
F
RQ
P
D
S
L
I
V
A
D
P
V
L
G
D
-
N
G
R
-
L
Y
--
T
NF
D
-
M
E
M
V
K
E
M
R
-
H
L
I
T
K
A
D
V
I
T
P
N
L
T
E
L
F
Y
L
L
D
------
E
----
P
YKADSTDE
E
L
K
E
---
Y
L
R
--
L
L
S
D
-
K
G
P
Q
V
V
I
I
T
S
V
----
P
---
V
H
D
E
-
P
H
K
T
S
V
Y
A
Y
N
R
Q
----
G
N
R
Y
W
K
V
T
C
P
Y
L
P
-
A
H
-
Y
-
P
G
T
G
D
T
F
T
S
V
I
T
G
S
L
M
Q
G
D
S
L
P
M
A
L
D
R
A
T
Q
F
I
L
Q
G
I
R
A
T
F
-------------------
65
HHSearch
58.70
24%
-35
- C4 -
-
3MBH
1
?
A:
[6-260]
-
K
V
K
K
I
A
A
V
H
D
L
S
G
M
G
R
V
S
L
T
V
V
I
P
I
L
S
S
M
G
F
Q
V
C
P
L
P
T
A
V
L
S
N
H
-----
T
Q
-
Y
P
G
--
F
S
F
L
D
L
T
D
E
M
P
K
I
I
A
E
W
K
K
L
-----
E
V
Q
F
D
A
I
Y
T
G
Y
L
G
S
P
R
Q
I
Q
I
V
S
D
F
I
K
D
---
F
RQ
P
D
S
L
I
V
A
D
P
V
L
G
D
-
N
G
R
-
L
Y
--
T
NF
D
-
M
E
M
V
K
E
M
R
-
H
L
I
T
K
A
D
V
I
T
P
N
L
T
E
L
F
Y
L
L
D
------
E
----
P
YKADST
D
E
E
L
K
E
---
Y
L
R
--
L
L
S
D
-
K
G
P
Q
V
V
I
I
T
S
V
----
P
---
V
H
D
E
-
P
H
K
T
S
V
Y
A
Y
N
R
Q
----
G
N
R
Y
W
K
V
T
C
P
Y
L
P
-
A
H
-
Y
-
P
G
T
G
D
T
F
T
S
V
I
T
G
S
L
M
Q
G
D
S
L
P
M
A
L
D
R
A
T
Q
F
I
L
Q
G
I
R
A
T
F
-------------------
11
PsiBlast_PDB
55.51
28%
-18
- C4 -
-
2I5B
1
PDXK_BACSU
A:
[7-250]
------
L
T
I
A
G
S
D
S
S
G
G
A
G
I
Q
A
D
L
K
T
F
Q
E
K
N
V
Y
G
M
T
A
L
T
V
I
V
A
M
D
PNNSW
N
H
Q
V
F
-------
P
I
D
T
D
--
T
I
R
A
Q
L
A
T
I
T
-
D
--
G
I
G
V
D
A
M
K
T
G
M
L
P
T
V
D
I
I
E
L
A
A
K
T
I
K
E
---
K
--
Q
L
K
N
V
V
I
D
P
V
M
V
C
K
G
A
N
-
E
V
LY
P
--
E
H
A
Q
A
L
R
E
--
Q
L
A
P
-
L
A
T
V
I
T
P
N
L
F
E
A
S
Q
L
S
G
MDELKT
V
----
D
--------
D
M
I
E
---
A
A
K
--
K
I
H
A
-
L
G
A
Q
Y
V
V
I
T
G
G
GKLK
H
---
E
K
A
V
-
D
-
V
----
L
Y
-
D
G
----
E
-
T
A
E
V
L
E
S
E
M
I
D
-
T
P
-
Y
T
H
G
A
G
C
T
F
S
A
A
V
T
A
E
L
A
K
G
A
E
V
K
E
A
I
Y
A
A
K
E
F
I
T
A
A
I
K
E
S
--------------------
13
PsiBlast_PDB
55.40
34%
-51
- C4 -
-
1UB0
6
?
A:
[17-246]
------------------
G
V
Q
A
D
L
K
V
F
F
R
F
G
V
Y
G
T
S
A
L
T
L
V
T
A
Q
N
-----
T
L
G
V
Q
R
--
V
H
--
L
L
P
P
E
--
V
V
Y
A
Q
I
E
S
V
A
-
Q
--
D
F
P
L
H
A
A
K
T
G
A
L
G
D
A
A
I
V
E
A
V
A
E
A
V
R
R
---
F
--
G
V
R
P
L
V
V
D
P
V
M
--------------
A
K
E
A
A
A
A
L
K
E
R
L
F
P
-
L
A
D
L
V
T
P
N
R
L
E
A
E
A
L
L
G
R
P
I
R
T
-
L
----
K
--------
E
A
E
E
---
A
A
K
--
A
L
L
A
-
L
G
P
K
A
V
L
L
K
G
G
----
H
---
L
----
E
-
A
V
D
L
L
A
T
R
G
G
----
V
-
L
R
F
S
A
--
P
R
V
H
-
T
R
N
T
-
H
G
T
G
C
T
L
S
A
A
I
A
A
L
L
A
K
G
R
P
L
A
E
A
V
A
E
A
K
A
Y
L
T
R
A
L
K
T
A
P
S
------------------
69
HHSearch
55.03
25%
-40
- C4 -
-
3H74
1
?
A:
[2-253]
-
S
L
S
T
M
L
V
A
E
D
L
S
A
V
G
G
I
S
L
S
S
A
L
P
V
L
T
A
M
Q
Y
D
V
A
A
L
P
T
S
L
L
S
T
H
-----
T
S
G
Y
G
T
--
P
A
--
V
V
D
L
S
--
T
W
L
P
Q
V
F
A
H
W
-
T
R
A
Q
L
H
F
D
Q
A
L
I
G
Y
V
G
S
V
A
L
C
Q
Q
I
T
T
Y
L
E
Q
---
Q
--
T
L
S
L
L
V
V
D
P
V
L
G
D
L
G
Q
L
Y
Q
G
--
F
--
D
-
Q
D
Y
V
A
A
M
R
Q
-
L
I
Q
Q
A
D
V
I
L
P
N
T
T
E
A
A
L
L
T
G
------
A
----
P
YQVTP---
D
L
E
V
I
L
P
A
L
Q
--
A
Q
L
K
-
T
G
A
H
A
V
I
T
D
V
Q
----
R
AD
Q
I
G
--------
C
A
W
L
D
E
A
----
G
-
H
V
Q
Y
C
G
A
R
R
L
P
-
G
H
-
Y
-
N
G
T
G
D
T
L
A
A
V
I
A
G
L
L
G
R
G
Y
P
L
A
P
T
L
A
R
A
N
Q
W
L
N
M
A
V
A
E
T
I
-------------------
79
HHSearch
54.78
21%
-18
- C4 -
-
4S1H
1
?
A:
[1-254]
-
M
T
N
K
V
L
T
I
S
S
Y
V
C
S
G
F
V
G
N
R
C
G
M
I
I
L
D
S
F
Q
I
Q
S
I
F
V
L
T
T
H
L
A
N
H
-----
T
-
G
Y
P
V
VG
G
S
--
G
V
L
L
N
--
D
F
I
S
I
M
D
S
L
E
V
N
HL
D
K
D
I
E
F
L
V
T
G
Y
F
P
S
S
D
L
V
Y
E
T
I
N
R
V
K
R
I
K
D
N
--
K
K
V
Y
F
L
C
D
P
I
L
G
D
-
N
G
K
-
M
Y
--
T
--
K
-
S
E
V
Q
D
S
M
K
E
-
L
I
K
Y
A
D
I
I
T
P
N
A
T
E
L
S
F
L
T
G
------
L
----
E
VNS
V
S
---
E
A
I
K
---
A
C
H
--
I
L
H
E
-
Q
G
I
P
V
I
L
V
T
S
I
----
K
---
E
G
N
D
-----
I
I
L
L
C
S
F
K
DTLN
N
-
K
N
F
T
I
K
I
P
R
I
E
-
G
D
-
F
-
T
G
V
G
D
T
L
T
Y
I
L
L
S
W
I
I
K
G
I
P
L
E
H
A
V
N
R
A
I
S
T
L
Q
T
I
L
R
N
T
V
G
------------------