@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : B0VQK4: (2017-11-27 )
MTDITLKTPVEMRNVQLKVYDNTDNSILIDTQVASLTSYDIKLPSTKLNRLYRIEVTTQGSSQVFDPTKSEYQNISGVYHAFITPSSISNKTQLISPSSEAIYQRAVIRSGQLPNETIIPTRIEQLHVDLASQDVYRSLLNAFKDTNIPSLSPASTLTILNLLKYSTTKPSTYVDSYLCFGYLQYWSSIHNTNSPYQDLTQSLATDLKDGYLDGKKLIGDKTSFTPIFTSAPDNIDPAKNTLLDIAANQKVTRDYFATNLRAATFKLADLQDQSHLDPIGYDLLDKKQYSGIIPAGNTSEFFRIDGAGDYRRAVGFSGITATCNGSAYPCKQGLTSINISDPKLPATDYLVGHYEDSTTGCQLNFRANGQIELIKGSQSYRSALSADSTDKLLQTDAASYSYLLNSSSSEPNNSTQQYNFIQLHIKANKIVSAQAGLDSRKAPDVLQTTQLEYSFS
Atome Classification :
(20 SA)
------------------.....--....10....-----...------.20...--.--....-30---......-.---.40..------.--..--...50.......-.--60.....-----...70.......--.80---------.........90....--....------100.-----.....--.110.-.......---120-------......---..--130.....-...140---..---..---...150........160-------........170........180.......190.....--------------..200.......210....---------..-.220------........--230.....-..240..-.....250.-......260.....-..270...-----....--------280..--....-..290.-----------..---....300...-..-----..310.......320...-....---330....-...-----340.---..-....350.......360.--....-..-370-........380.......390--........400-.......410.......420....------...430.......440...--...-.450....------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
------------------MT
D
I
T
--LKTP
V
E
M
R
N
V
-----
Q
L
K
------
V
Y
DNTD--
N
--
S
I
L
I
-
D
T
---
Q
VAS
L
T
-
S
---
Y
D
I
KL------P--ST--KL
N
R
L
Y
R
I
E
V
T
T-Q--GSSQVFD-----P
T
K
S
E
Y
Q
N
IS
G
V
--
Y
H
----------
A
F
ITPSSISNK
T
Q
L
I--SP
S
S
------
E
A
I
Y
-----
Q
R
A
V
I--RSG-Q-LPNETII---
P
T
--------
R
I
E
Q
L
H
---
V
D--L
A
-
S
Q
D
V
Y
-
R
S
L
L
N
A
---FK---DT---NIPS-LSP
A
S
T
L
T
I
L
N
--------
L
L
KYSTTK
P
S
-
T
Y
V
D
S
Y
L
C
F
G
Y
L
Q
Y
W
S
S
IHNTNS
P
Y
Q
--------------
D
L
T
Q
S
L
A
T
D
L
K
DGYLD
G
K
K
---------LI-GDK-------TSF
T
P
I
FT--SAPDNIDP-AKN
T
L
L
D
-IAANQ
K
V
T
R
-
D
Y
F
A
TNL
R
A
A
T
F
K
L
-ADLQDQSH-----LDPI--------
G
Y
-
D
L--LDKK-QYS
G
I
I-----------PA---GNTS
E
F
F
R
ID-GA-----G
D
Y
R
R
AVGFS
G
I
T
A
TCNG-SAY
P
---
C
KQG
L
T
S-INI-----SDPK---LP-ATD
Y
L
V
G
HYEDSTT
G
C
Q
L
--
N
F
RA-N
G
-
Q
I
--
E
L
I
KG
S
Q
S
Y
R
S
ALSADS
T
D
K
---
L
L
Q
TDAA
S
Y
S
Y
-
L
LNSSSSEPNNST
Q
Q
Y
N
F
I
Q
L
H
I
K------AN
K
I
V
S
AQAGLDSRKAPDV--
L
Q
T
-
T
Q
L
E
Y
SFS------------------------------------------------------------
18
Fugue
66.41
22%
17
* C6 *
-
4FHL
9
YEKI_SCHPO
A:
[2-392]
--------------G
S
M
T
L
S
S
N
Q
--
Y
Q
L
P
L
N
V
R
P
Y
-----
T
T
T
------
W
C
S
Q
S
P
--
S
CS
N
L
L
A
-
I
G
---
H
D
T
G
I
T
-
I
---
Y
C
A
S
E
------
E
--
S
T
G
L
T
L
Q
E
L
F
T
I
Q
T
G
L
-
P
--
T
L
H
L
S
F
S
-----
S
S
C
S
Y
S
E
N
-
S
P
V
--
Y
S
----------
L
F
L
A
C
V
C
Q
D
N
T
V
R
L
I
--
I
T
K
N
------
E
T
I
I
-----
T
Q
H
V
L
G
G
K
S
G
-
H
-----------------------
H
N
F
V
---
N
D
--
I
D
-
I
A
D
V
Y
-
S
A
D
-
N
R
---
L
A
---
E
Q
---
V
I
A
S
-
V
G
D
D
C
T
L
I
I
W
R
--------
L
T
D
E
G
P
I
L
A
G
-
Y
P
L
S
S
P
--
G
I
S
V
Q
F
R
P
S
--------------------------------------
N
P
N
Q
---------
L
I
V
G
E
R
-------
N
G
N
I
R
I
F
D
--
W
T
L
N
L
T
E
L
-
V
K
N
P
W
L
L
-
T
L
N
T
L
P
L
V
N
-
S
S
L
A
-
N
V
R
W
I
---------------------------------------
G
S
-
D
G
S
G
I
L
-----------
A
M
---
C
K
S
G
A
W
L
R
W
N
-
L
--------------
F
K
N
L
L
P
N
V
Q
G
I
S
L
F
P
---
S
L
L
G
------------
A
C
P
H
---
P
R
-
Y
M
D
Y
F
A
T
A
H
S
Q
--------------
H
G
-
L
I
--
Q
L
I
N
T
Y
E
------------------------------
K
D
S
N
S
I
P
I
Q
L
G
M
P
I
V
D
F
C
W
H
Q
D
------
G
S
H
L
A
I
A
T
E
G
-------
S
V
--
L
L
T
-
R
L
M
G
F
T
--------------------------------------------------------------
13
Fugue
62.04
19%
24
* C3 *
-
4RAP
-
TIBC_ECOH1
A:
[10-391]
---ITPPDTPT
Q
A
G
P
EN
I
F
Y
D
F
N
D
G
A
R
V
L
L
P
E
G
K
W
-----
H
V
R
------
L
L
D
A
D
S
--
E
--
N
I
L
F
-
C
C
---
D
V
D
K
--------
G
W
V
T
------
S
--
S
K
--
K
Y
F
V
R
F
R
I
Q
V
F
R
-
Q
--
G
A
T
P
L
L
D
-----
E
T
-----------------------------
L
K
L
K
D
R
P
V
L
I
--
S
F
P
T
------
G
---------------
T
L
G
-
D
-
L
L
G
W
F
P
Y
---
A
E
--------
R
F
Q
S
L
H
KCR
L
E
--
C
T
M
S
Q
D
I
I
-
D
L
L
A
P
Q
---
Y
P
---
Q
-----------------------------
I
Q
F
S
T
P
D
K
P
-
R
T
V
A
P
Y
A
T
Y
R
V
G
L
Y
F
G
G
--
D
T
N
N
Q
P
V
--------------
D
F
R
K
V
G
F
H
R
-
S
A
G
Y
I
L
G
------------
V
-
D
P
R
-------
E
A
P
V
R
L
D
L
--
S
A
P
R
V
I
A
A
-
P
---
Y
V
C
-
I
A
T
Q
S
T
C
Q
A
-
K
Y
W
N
N
G
T
--------
G
W
S
E
V
I
A
H
-----
L
K
S
L
--------
G
Y
-
R
V
M
C
I
D
R
D
-
A
H
Y
G
Q
G
-----------
F
V
---
W
N
H
I
P
W
-----
G
A
-----
E
D
F
-------------------------
T
G
K
L
P
-
L
Q
E
-----
R
V
N
L
---
L
R
-
H
A
S
F
F
I
G
----
L
P
S
G
L
S
W
--
L
A
W
A
-
T
R
I
P
V
--
V
L
I
S
G
---
F
S
L
P
N
S
E
F
Y
T
P
W
---
R
V
F
N
S
H
G
C
Y
G
C
-
W
D
D
T
S
---
L
N
F
D
H
H
D
F
L
W
C
P
R
H
K
N
------
T
D
R
Q
F
E
C
T
R
L
I
T
G
A
Q
V
N
G
V
--
I
N
K
-
L
H
R
S
L
T
--------------------------------------------------------------
15
Fugue
55.57
20%
38
- C2 -
-
4MFL
3
?
A:
[23-345]
------------------
M
D
P
E
T
--
V
R
I
A
L
G
L
-------------------
E
E
R
T
--
A
--
A
W
L
T
-
E
L
---
D
E
L
G
P
P
-
A
---
E
P
V
R
L
------
P
R
G
E
E
--
A
R
D
L
L
R
R
L
E
V
P
E
-
L
--
D
A
E
E
I
V
A
-----
A
A
--------------------------
P
D
P
D
R
D
P
A
L
W
W
L
L
--
E
R
T
H
------
H
A
I
V
R
H
MGD
H
R
A
K
P
--
R
G
G
-
P
P
L
P
Y
E
G
G
A
---
A
A
--------
R
Y
F
H
V
Y
---
V
F
--
L
A
-
T
V
P
A
V
-
R
R
F
H
A
E
R
GI
P
D
---
E
V
---
G
W
E
T
-
L
T
Q
L
G
E
L
V
A
I
H
--------
R
R
K
Y
G
Q
G
G
------------
M
N
M
Q
W
W
T
T
Y
H
L
R
G
I
L
Y
R
LG------------
R
L
Q
F
S
L
A
T
G
-
K
D
G
T
------------------------------
P
H
L
G
L
--
A
V
P
E
W
G
G
P
-
L
-------------
L
P
K
-
A
Y
D
E
S
L
H
R
A
R
P
F
F
D
-
R
H
F
P
E
H
G
A
-----
R
V
A
W
--------
G
S
-
S
W
--
M
L
D
P
-
Q
L
E
E
Y
L
-----------
T
-----
E
D
S
N
I
I
Q
L
A
---------------------------------------
R
F
-
W
T
L
-----
T
D
S
A
---
P
E
-
P
-----
G
N
A
D
G
D
S
S
I
L
E
F
--
V
F
R
Y
-
N
G
-
Q
------------------------------------------
P
L
D
E
L
P
Q
R
S
S
L
E
R
A
V
I
A
H
L
K
------
A
G
R
------
H
W
H
M
R
T
G
F
V
K
--
L
P
----------------------------------------------------------------------
16
Fugue
54.43
16%
28
- C3 -
-
4PW2
1
?
A:
[72-585]
RY
E
E
I
D
C
L
I
ND
D
A
T
I
K
G
R
R
E
G
S
E
--
V
Y
M
P
F
S
W
M
E
K
-----
Y
F
E
------
V
Y
G
K
V
V
--
Q
--
Y
D
G
Y
-
D
R
---
F
E
F
S
H
S
-
Y
---
S
K
V
Y
A
Q
REQYH
P
--
N
G
--
V
F
M
S
F
E
G
Y
N
V
E
V
-
R
--
D
R
V
K
C
I
S
GVEG
V
P
L
S
T
Q
W
G
P
Q
G
Y
F
--
Y
A
----------
I
Q
I
A
Q
Y
G
L
S
H
Y
S
K
N
L
T
E
R
P
P
H
------
V
E
V
Y
-----
D
T
A
E
E
--
R
S
A
W
T
-
V
P
K
G
C
S
L
---
T
R
V
Y
D
KTRA
T
S
V
R
E
F
S
---
A
P
--
E
N
-
S
E
G
V
S
-
L
P
L
G
N
T
---
K
D
F
I
I
S
F
---
D
L
K
F
-
T
S
N
G
S
V
S
V
I
L
E
T
TEK
G
P
P
F
V
I
H
Y
V
T
T
T
Q
L
I
L
L
K
D
R
D
I
T
Y
G
I
--------
G
P
R
T
T
W
T
--------------
T
V
T
R
D
L
L
T
D
L
R
K
G
I
G
L
S
N
T
---------
K
A
-
V
K
A
-------
T
K
--------
T
M
P
R
R
V
V
K
-
L
V
V
H
G
T
G
-
T
I
D
N
I
T
I
S
T
-
T
S
H
M
A
A
F
Y
A
A
S
D
W
L
-
V
R
N
Q
D
E
R
G
-----
G
W
P
I
M
V
T
R
K
LGE
G
F
-
R
A
--
L
E
P
G
-
W
Y
S
A
M
A
-----------
Q
G
---
Q
A
M
S
T
L
V
R
A
Y
-
L
M
TKD--
D
R
Y
L
K
A
A
L
R
A
T
G
P
F
K
L
P
S
-
E
Q
H
G
---
V
K
A
V
F
M
N
K
Y
D
W
Y
E
EYP
T
I
P
S
SFV
L
N
-
G
F
I
Y
S
L
I
G
L
F
D
L
A
Q
T
A
G
E
--
K
L
G
R
-
D
A
-
G
Q
--
L
Y
S
K
G
M
E
S
L
K
V
M
L
P
L
Y
D
T
G
S
---
G
T
I
Y
D
L
R
H
F
I
L
-
G
T
A
P
N
L
A
R
W
D
Y
H
T
T
H
I
N
Q
L
Q
L
L
G
T
------
I
D
N
--
S
P
I
F
R
D
S
V
K
R
W
K
S
Y
--
L
K
G
-
G
R
A
K
H
N
--------------------------------------------------------------
12
Fugue
53.46
23%
62
* C5 *
-
5T1P
2
?
A:
[22-347]
-------------------------------------------------
I
D
E
N
L
I
--
K
--
A
A
Q
A
-
E
G
---
R
V
N
S
L
A
M
P
DTW
A
N
W
K
D
------
T
--
W
A
--
D
L
K
N
L
Y
D
I
E
H
S
D
-
T
D
M
S
S
A
Q
E
I
A
-----
K
F
K
T
E
K
K
N
A
S
G
------------------------
D
I
G
D
V
G
--
A
S
F
G
------
E
I
A
V
-----
K
Q
G
V
A
--
Q
P
F
-
K
-
T
S
Y
W
D
Q
I
---
P
T
--------
W
A
K
D
K
D
---
G
N
WL
L
A
-
Y
T
G
T
I
-
A
F
I
V
N
K
---
D
V
---
V
K
---
D
I
P
K
--------
T
W
Q
D
--------
L
L
K
G
N
-------------------
Y
K
I
T
V
G
D
V
S
V
A
A
Q
--------------
A
V
S
A
V
L
A
A
N
Y
A
L
G
------------------
G
D
E
-------
K
-------------
D
L
S
P
-
A
L
A
F
F
N
T
-
L
A
K
Q
G
R
L
V
N
N
D
V
S
I
A
N
L
E
K
G
E
V
E
V
-
G
L
V
W
---
D
-----
F
N
G
L
--------
G
Y
R
D
K
--
V
G
K
D
-
R
Y
E
V
L
I
-----------
P
A
------------
D
-
G
----------------------------
S
---
V
I
S
G
Y
T
T
-
I
I
N
-----
K
Y
A
K
---
H
P
-
N
A
A
K
L
A
R
E
F
I
L
S
-----------
D
-
K
G
-
Q
I
--
N
L
A
K
G
---
Y
A
R
P
I
R
I
D
H
I
T
-----------------
L
P
D
D
I
K
A
K
L
L
P
S
E
Q
Y
K
N
A
R
A
I
K
D
------
Q
K
A
W
E
K
S
A
K
E
L
P
Q
L
W
Q
E
K
V
--
I
V
D
M
K
-------------------------------------------------------------------
21
Fugue
51.73
21%
65
- C6 -
-
5DL8
3
?
A:
[17-407]
--------------------
N
P
N
--
Q
Q
T
E
D
E
W
K
F
T
-----
L
K
N
------
A
Y
I
N
R
D
F
D
N
--
D
A
L
K
-
D
T
G
S
W
S
Q
A
A
S
L
-
F
---
Y
K
S
K
M
------
H
--
D
T
--
P
L
V
I
A
D
K
P
I
T
I
G
-
A
--
D
A
S
V
Q
Y
A
-----
V
R
L
S
S
D
K
H
V
A
D
------------------
T
V
L
P
F
N
K
E
T
Q
----
S
Q
A
S
------
D
Y
L
K
-----
Y
G
A
T
L
--
K
L
G
-
Y
---
D
K
T
L
L
---
S
V
--------
G
E
L
W
L
D
---
L
P
--
V
T
-
A
V
D
A
S
-
R
Q
L
L
T
S
---
Y
W
---
G
T
---
N
L
K
S
Q
L
S
D
Q
L
Y
A
E
I
G
R
--------
V
E
K
V
S
P
R
N
E
-----
E
D
F
K
K
F
S
F
T
A
N
G
I
T
K
E
S
D
G
L
N
Y
I
--------------
D
L
R
Y
Q
F
T
P
S
L
K
G
E
Y
Y
F
G
N
L
-------------------------------------------
E
D
L
Y
N
-
K
H
Y
V
G
L
E
H
T
-
W
K
Q
P
T
F
A
L
T
S
K
F
K
Y
-
F
N
A
K
D
----------------------------
D
G
N
-
T
F
D
--
I
-----------
D
A
---
E
N
I
G
L
L
E
T
V
K
-
V
------
K
N
H
T
F
G
L
G
Y
Q
Q
I
I
---
G
E
-
S
A
Y
P
-------------
L
-----
P
D
G
F
---
L
P
-
E
T
Y
F
I
---------------
N
W
N
A
-
T
G
-
F
F
--
K
--
E
D
E
K
S
Y
H
V
M
Y
G
Y
D
F
K
D
Y
IPG
L
N
A
M
V
K
Y
V
Y
G
H
-
D
F
K
A
A
N
G
E
K
N
H
E
T
E
S
N
V
I
L
N
Y
A
F
Q
-----------------
Q
P
L
L
K
G
F
A
--
L
Q
Y
-
I
R
I
D
Y
N
V
K
H
G
N
D
F
G
E
D
R
L
F
V
N
Y
T
K
K
F------------------------------------------
14
Fugue
50.29
18%
11
* C2 *
-
5AKP
2
BPHY_XANC8
B:
[18-638]
---------------------
V
C
--
A
R
E
P
I
H
I
P
G
L
IQPY
G
V
L
L
------
V
I
D
P
A
D
--
G
--
R
I
V
Q
A
S
T
---
T
A
A
D
L
--------
L
G
V
------
P
--
M
A
--
A
L
L
G
M
P
Y
T
Q
V
L
T
-
L
--
P
E
A
Q
P
F
A
-----
V
D
D
Q
P
Q
H
L
M
H
A
E
--
V
R
F
PQRATPPA
S
A
W
V
A
A
W
H
L
Y
P
Q
Q
W
L
V
--
E
M
E
P
RDARLL
D
V
T
L
-----
R
E
A
M
P
--
L
L
R
-
S
-
V
E
R
D
P
G
I
---
A
E
--------
A
A
V
R
V
A
---
K
G
--
L
R
-
S
L
I
G
F
D
R
V
M
I
Y
R
---
F
D
---
E
E
WNG
D
I
I
A
-
E
A
R
K
P
E
L
E
A
Y
L
--------
G
L
H
Y
P
A
S
D
I
P
-
A
Q
A
R
A
L
Y
L
R
N
R
V
R
Q
I
A
D
V
G
Y
Q
P
S
P
I
Q
PTVHPQLGTPVDLS
D
V
S
L
R
S
V
S
P
V
H
L
E
Y
L
A
N
M
G
VT
A
T
L
V
A
S
I
V
V
-
N
D
A
LWGLI
S
C
H
H
Y
S
P
H
F
T
N
H
A
M
R
D
V
T
D
A
-
V
A
R
T
L
A
G
R
I
G
A
L
Q
A
V
A
R
-
A
R
L
E
S
V
L
L
T
V
R
E
K
L
I
T
D
F
N
D
A
E
H
MT
V
E
L
L
D
D
M
--------
A
P
-
D
L
--
M
D
V
V
-
D
A
D
G
V
A
I
F
H
GNDISRHG
T
T
---
P
D
V
A
A
L
R
R
I
R
-
D
H
I
E
SEH
H
E
A
L
R
E
D
A
V
G
A
L
H
V
D
A
I
G
-
E
V
F
P
ELA
D
L
A
P
L
A
A
-
G
F
I
-----
F
V
P
L
---
M
P
Q
S
R
S
A
L
L
W
T
R
R
E
Q
I
Q
Q
I
K
W
AG
N
P
R
K
-
S
F
-
D
L
W
Q
Q
T
V
R
G
R
A
R
R
W
S
P
L
H
L
E
S
A
R
S
---
L
R
V
L
I
E
L
M
E
R
K
-
R
F
Q
Q
D
F
T
L
L
E
A
S
L
S
R
L
R
D
G
V
A
I
I
E
R
G
T
ANA
A
H
R
L
L
F
V
N
T
A
F
A
D
V
C
G
S
D
V
AE
L
I
G
-
R
E
L
Q
T
L
Y
A
SDAP
R
A
N
V
E
L
L
Q
D
A
L
R
N
G
R
A
A
Y
V
T
L
P
L
QVSDGA
P
V
Y
R
Q
F
H
L
E
P
L
P
SPSGVTA
H
W
L
L
Q
L
R
D
19
Fugue
49.87
14%
52
- C5 -
-
4J1Q
1
A:
[20-445]
-----------------H
M
E
R
L
M
--
L
E
P
V
W
E
K
Q
N
E
-----
E
L
S
YT
E
H
I
I
V
L
F
E
T
E
--
R
--
S
V
T
D
-
S
I
---
A
S
H
M
K
D
-
A
---
R
V
I
T
L
------
N
--
E
A
--
V
G
H
I
A
E
R
Y
Q
C
Y
M
-
Q
--
N
I
F
E
L
L
Q
-----
S
K
V
R
K
L
S
A
G
R
I
I
--
I
Q
----------
A
I
V
P
L
----
E
K
E
K
Q
L
--
F
A
G
V
------
S
G
L
F
-----
K
T
A
E
I
--
E
F
S
-
K
-
L
T
A
Q
V
I
E
I
EK
P
E
--------
E
M
I
D
L
H
---
L
K
--
L
K
-
D
D
S
-------
R
R
---
P
F
---
D
K
---
Q
I
R
Y
-
E
A
G
Y
R
F
V
K
G
W
R
--------
E
M
V
D
T
L
H
M
P
W
-
R
D
E
G
V
Y
L
I
T
G
---------
G
A
G
S
L
G
L
--------------
L
F
A
K
E
I
A
N
R
T
G
R
--------------------------------
S
T
I
V
L
--
T
G
R
S
V
L
S
E
-
D
K
E
N
E
L
E
-
A
L
R
S
I
G
A
-----------
E
V
V
Y
R
E
-
A
D
V
S
D
Q
H
A
-----
V
R
H
L
--------
L
E
-
E
I
--
K
E
R
Y
G
T
L
N
G
I
I
H----------
G
A
---
G
S
S
K
D
R
F
I
I
H
K
T
N
-----
E
E
F
Q
E
V
L
--------------
Q
P
---
K
V
S
G
L
L
H
-
V
D
E
-----
C
S
K
D
---
F
P
-
L
D
F
F
I
F
F
S
S
V
S
G
C
L
G
N
A
G
--
Q
A
D
Y
-
A
A
-
A
N
--
S
F
M
D
A
F
A
E
Y
R
R
S
L
A
A
S
K
K
R
------
F
G
S
T
I
S
F
N
W
P
L
W
E
E
G
G
M
Q
V
G
A
E
D
E
K
R
M
L
K
T
T
G
M
V
------
P
M
P
T
D
S
G
L
K
A
F
Y
Q
G
I
V
S
D
K
--
P
Q
V
-
F
V
M
E
G
Q
L
Q
K
M
K
Q
K
LL-----------------------------------------------------
7
HHSearch
42.34
20%
-125
- C7 -
-
4GQZ
-
?
C:
[94-135]
---------------------------------
P
F
-----
T
V
K
------
V
T
D
S
-
K
--
G
--
A
V
I
V
-
Q
K
E
--
M
Q
S
Y
R
N
-
G
F
--
I
G
V
W
L
------
P
--
R
-----
N
M
E
G
T
L
E
V
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
HHSearch
42.07
15%
-56
- C- -
-
3D33
-
?
B:
[66-130]
---------------------
L
T
--
L
K
N
A
S
P
D
R
D
M
-----
T
I
R
------
I
T
D
M
A
K
--
G
--
G
V
V
Y
-
E
N
D
--
I
P
E
V
Q
S
-
A
Y
--
I
T
I
S
I
------
A
--
N
F
---
P
A
E
E
Y
K
L
E
I
T
G
T
P
--
S
G
H
L
T
G
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
41.51
15%
-56
- C- -
-
3D33
-
?
A:
[66-130]
---------------------
L
T
--
L
K
N
A
S
P
D
R
D
M
-----
T
I
R
------
I
T
D
M
A
K
--
G
--
G
V
V
Y
-
E
N
D
--
I
P
E
V
Q
S
-
A
Y
--
I
T
I
S
I
------
A
--
N
F
---
P
A
E
E
Y
K
L
E
I
T
G
T
P
--
S
G
H
L
T
G
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
37.58
12%
-92
* C7 *
-
4G5A
-
?
A:
[42-92]
-------------------------------
F
A
P
I
-----
T
V
E
------
V
K
D
I
E
---
K
--
Q
I
V
F
-
Q
S
I
--
I
F
P
V
A
A
G
E
---
Y
T
L
Y
L
------
G
--
D
L
---
S
L
G
Q
Y
E
L
Y
M
Y
N
-
A
--
S
V
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
30.97
25%
-26
- C7 -
-
3EB7
-
?
A:
[314-404]
---------------------------------
S
I
-----
Q
T
Q
------
T
Y
G
T
T
S
--
G
--
S
S
V
I
-
A
T
---
Q
Q
I
G
F
T
-
G
---
F
D
V
--------------------
Y
K
----
T
-
L
--
S
T
A
G
V
L
F
-----
A
Y
T
S
K
Y
Y
G
V
S
K
V
--
V
F
----------
D
A
I
Y
P
D
N
K
Y
K
T
T
F
T
Y
--
N
P
G
S
------
E
G
I
G
-----
A
Q
E
K
D
--
S
E
V
-
E
-
L
P
P
E
T
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
27.74
18%
29
* C1 *
-
4JN6
-
ACDH_MYCTU
B:
[168-275]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
I
D
--------------
E
F
T
K
T
T
A
R
G
V
Q
-------
T
---------
I
G
-
G
A
A
-------
R
G
-
K
A
I
I
I
--
L
N
P
A
D
P
P
M
I
M
R
D
T
I
F
C
-
A
I
P
T
D
-
A
D
R
-----
E
A
I
A
A
S
I
H
D
V
-
V
K
E
V
Q
T
Y
--------
V
P
--------
G
Y
-
R
L
--
L
N
E
P
-
Q
F
D
E
P
S
I----------
N
S
GG
Q
A
L
V
T
T
F
V
E
V
E
-
G
A
-----
G
D
Y
L
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
26.74
15%
-60
* C4 *
-
4JMH
-
?
A:
[3-73]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
---
F
N
-
S
L
D
E
L
V
D
Y
H
R
S
T
S
V
S
R
N
Q
--
Q
I
F
L
-
R
D
-
I
G
----
G
G
G
H
P
W
Y
K
G
K
I
P
R
A
K
A
E
E
---
M
L
S
K
Q
R
H
D
G
A
F
-
L
I
R
E
S
E
S
A
P
G
-----------------------------------------------------------------------------------------------------------------
20
Fugue
25.75
23%
-74
- C1 -
-
2MIX
-
T3A_TERVA
A:
[1-21]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
R
I
C
C
G
--
C
Y
W
N
G
S
K
D
V
C
S
Q
S
C
--------------
C
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
17.90
15%
46
- C4 -
-
2MV3
-
YME1_YEAST
A:
[101-180]
----------------------------------------------------------------------------------------------------
H
A
M
L
A
T
R
E
Q
E
A
-
N
--
K
D
L
T
S
P
D
-----
A
Q
A
A
F
Y
K
L
L
L
Q
S
NY
P
Q
----------
Y
V
V
S
R
F
--
E
T
P
G
I
A
S
--
S
P
E
C
------
M
E
L
Y
-----
M
E
A
L
Q
--
R
I
G
-
R
-
H
S
E
A
D
A
V
---
R
Q
--------
N
L
E
H
H
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
16.22
24%
38
- C4 -
-
2K8E
-
YEGP_ECOLI
A:
[50-113]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-
S
K
T
S
---
A
E
K
G
I
A
S
-
V
R
S
-----
N
S
P
Q
---
E
E
-
R
Y
E
----
K
K
T
A
S
N
G
K
F
Y
F
--
N
L
K
A
A
N
H
-
Q
I
--
I
G
S
--
S
Q
M
Y
A
T
A
Q
S
R
E
T
G
I
A
---
S
V
-------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
0.16
22%
-
- C- -
-
3HFO
-
?
A:
[5-26]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
G
---
L
P
-
S
V
R
Q
V
Q
L
L
I
K
D
Q
-
T
P
V
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
0.16
22%
-
- C- -
-
3HFO
-
?
B:
[5-26]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
S
G
---
L
P
-
S
V
R
Q
V
Q
L
L
I
K
D
Q
-
T
P
V
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------