@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : I3TYT9: (2017-12-15 )
MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIKIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLYDNLALYEYVIDLCLSRGGTLF
Atome Classification :
(20 SA)
---------------------------------.........10.------------..--..--...20........30....--..-..40........--50.-----------......----..60-.--.......70....----..---..-80-..----...------....90......--------..100...-.--..--.110.-----....-----..120-----......---.-130.......140....---...150--.......-160-----.-....---------...170.......180------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
---------------------------------MTTEHFDLANPV------------TK--VD--DIP
D
Y
E
M
Y
S
Q
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I
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S
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N
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--
G
N
-
R
V
L
K
G
I
K
I
G
Y
IA--S-E-----------K
D
R
I
I
D
----
Y
LAD-K--DY
D
L
K
L
L
S
V
HHNG----QF---DY-L--D
D
----
E
V
K------DMDP
A
I
V
I
P
Q
Y
F
--------
A
Q
L
S
E
A
L
V
-
V
--
I
E
--
A
D
V
F
A
-----
H
FDY-----
G
F
R
V
F-----GL
S
V
A
E
---
F
-
K
Q
Y
E
A
Q
F
L
P
I
L
D
Q
V
I
K
N---K
L
A
F
E
L--NAK
S
A
Y
L
-
Y
-
D
-----
N
-
L
A
L
Y
---------
E
Y
V
I
D
L
C
L
SRGGTLF-------------------------------------------
18
HHSearch
79.66
15%
-23
- C9 -
-
2YXO
1
?
B:
[34-220]
---------------------------------
V
F
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P
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P
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Y
------------
D
P
ES
R
M
--
R
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Q-
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--
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-
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-----------
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A
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----
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R
-
Y
--
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----
A
W
---
P
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-
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--
H
P
DHQE
E
Y
A
------
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R
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L
K
E
V
F
R
A
Y
F
--------
Q
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A
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--
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--
F
H
A
I
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-----
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L
-----
P
K
K
F
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-----
H
R
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-----
E
-
E
A
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A
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P
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A
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A
---
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--
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R
-
P
-
A
K----
E
-
V
Y
P
A
---------
P
A
L
L
R
R
A
R
E
L
G
I
G
L
V
-------------------------------------------
17
HHSearch
74.46
20%
-28
- C9 -
-
4GC3
-
HIS9_LACLA
A:
[38-221]
---------------------------------
C
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----------------
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--
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--
R
-
F
-----------
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----
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-
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--
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----
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---
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--
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----
E
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L-----
Q
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K
E
E
A
Q
R
E
Y
L
--------
L
A
C
L
D
V
V
Q
N
F
--
E
N
--
Y
N
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F
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-----
H
L
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Y
-----
V
A
R
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-----
P
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IK-
F
-
A
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N
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L
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E
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A
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A
S
K
---
E
K
A
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I
--
N
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F
D
D
-
P
-
K
-----
T
-
E
Q
F
Y
---------
S
D
L
L
I
N
F
K
R
L
G
G
K
---------------------------------------------
16
HHSearch
74.07
20%
-26
- C9 -
-
4GK8
2
HIS9_LACLA
A:
[38-221]
---------------------------------
C
F
T
E
H
R
D
F
Y
F
P
G
----------------
M
D
--
F
S
L
N
L
P
E
Y
F
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-
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--
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-
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-----------
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----
F
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-
A
--
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----
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---
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--
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----
E
F
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L-----
Q
K
T
K
E
E
A
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R
E
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L
--------
L
A
C
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V
Q
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--
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--
Y
N
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-----
H
L
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Y
-----
V
A
R
Y
G
-----
P
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IK-
F
-
A
E
N
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E
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E
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A
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K
---
E
K
A
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E
I
--
N
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L
F
D
D
-
P
-
K
-----
T
-
E
Q
F
Y
---------
S
D
L
L
I
N
F
K
R
L
G
G
K
---------------------------------------------
34
Fugue
72.64
16%
35
* C9 *
-
2YXO
1
?
A:
[1-263]
MVDS
H
V
H
T
PLCGHAEGH
P
E
A
Y
L
E
E
A
R
A
K
GLK
G
V
V
F
T
D
H
S
P
M
P
P
W
Y
------------
D
P
--
E
S
RM
R
L
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A
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F
Y
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L
A
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--
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A
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P
--
G
-
T
-----------
E
G
F
L
A
Q
----
L
L
R
R
-
Y
--
P
F
D
Y
V
I
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S
V
H
Y
L
G
AWPL
D
H
---
P
D
-
H
--
Q
E
----
E
Y
A
------
W
R
D
L
K
E
V
F
R
A
Y
F
--------
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E
V
E
K
A
A
R
-
S
--
G
L
--
F
H
A
I
G
-----
H
L
D
------
L
P
K
K
F
-----
G
-
H
R
L
P
---
E
-
E
A
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L
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L
A
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P
A
L
R
A
V
A
E
A
---
G
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--
N
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A
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L
R
R
P
A
-
K
-----
E
-
V
Y
P
A
---------
P
A
L
L
R
R
A
R
E
L
G
I
G
L
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L
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SDAHRPEEVGFA
F
P
E
V
Q
A
L
L
A
G
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GFR
E
A
Y
Y
F
V
EG
S
P
V
A
Y
P
L
14
HHSearch
63.15
15%
24
- C9 -
-
3DCP
-
?
A:
[36-254]
---------------------------------
S
I
V
E
H
A
P
L
S
S
E
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M
K
N
TAGDKEAVT
T
A
--
S
M
--
A
M
S
D
L
P
Y
Y
F
K
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M
N
H
I
K
K
K
Y
A
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D
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-
L
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I
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D
Y
L
I
--
G
-
Y
-----------
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D
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T
R
D
----
F
L
N
E
-
Y
GP
Q
T
D
D
G
V
L
S
L
H
F
L
E
G---
Q
G
GFR
S
I
-
D
FS
A
E
----
D
Y
N
E
G
IVQF
Y
G
G
F
E
Q
A
Q
L
A
Y
L
--------
E
G
V
K
Q
S
I
E
-
A
DL
G
L
FK
P
R
R
M
G
-----
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I
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L
-----
C
Q
K
F
Q
-----
Q
F
F
G
E
D
TSD
F
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E
E
V
M
E
K
F
R
V
I
L
A
L
V
K
K
R
---
D
Y
E
L
D
F
--
N
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A
G
L
F
K
-
P
-
L
C----
G
E
T
Y
P
P
---------
K
K
I
V
T
L
A
S
E
L
Q
I
P
F
V
-------------------------------------------
35
Fugue
61.15
21%
14
- C1 -
-
5MLC
-
RK13_SPIOL
L:
[55-250]
-------------------------------TK
C
T
E
E
W
R
Q
L
K
E
A
V
------------
K
K
--
E
F
--
A
I
P
H
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P
L
D
Q
R
W
M
F
T
L
E
E
A
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--
G
P
-
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N
--
T
T
W
Y
P
K
--
S
-
A
-----------
D
H
V
P
T
D
----
K
----
K
--
W
Y
V
V
D
A
T
D
L
I
L
G
R
----
M
A
---
S
T
-
I
--
A
I
----
H
I
R
------
G
K
N
L
A
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S
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----------
D
M
G
A
F
V
I
-
V
--
V
N
--
A
D
K
V
A
VSGKK
R
T
Q
K
-----
L
Y
R
R
H
SGRPG
G
L
K
E
E
T
---
F
-
D
Q
L
Q
K
R
---
I
P
E
R
I
I
E
H
---
A
V
R
G
M
L
PK
G
R
L
G
R
Y
L
-
F
-
N
-----
H
-
L
K
V
Y
KGAEHPHQA
Q
Q
P
I
D
L
P
L
R
D
K
R
I
R
V
EK-----------------------------------------
15
HHSearch
60.84
15%
23
- C9 -
-
3DCP
-
?
B:
[36-254]
---------------------------------
S
I
V
E
H
A
P
L
S
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TAGD
K
E
A
V
T
T
A
--
S
M
--
A
M
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L
P
Y
Y
F
K
K
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I
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K
K
Y
AS
D
L
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D
Y
L
I
--
G
-
Y
-----------
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D
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R
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----
F
L
N
E
-
Y
GP
Q
T
D
D
G
V
L
S
L
H
F
L
E
G---
Q
G
GFR
S
I
-
D
FS
A
E
----
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Y
N
E
GIVQF
Y
G
G
F
E
Q
A
Q
L
A
Y
L
--------
E
G
V
K
Q
S
I
E
-
A
DL
G
L
FK
P
R
R
M
G
-----
H
I
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L
-----
C
Q
K
F
Q
-----
Q
F
F
G
E
D
TSD
F
S
E
E
V
M
E
K
F
R
V
I
L
A
L
V
K
K
R
---
D
Y
E
L
D
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--
N
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A
G
L
F
K
-
P
-
L
C----
G
E
T
Y
P
P
---------
K
K
I
V
T
L
A
S
E
L
Q
I
P
F
V
-------------------------------------------
27
HHSearch
59.99
20%
-46
- C9 -
-
2W9M
-
?
A:
[360-494]
---------------------------------
G
T
A
D
H
S
R
A
A
Y
Y
A
------------
N
---
G
L
--
T
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R
A
---
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D-
G
-
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-----------
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P
D
D
----
V
L
G
-----
E
L
D
Y
V
V
V
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V
H
S
N
F
----
T
--------------------------
L
----
D
A
A
R
Q
T
--------
E
R
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V
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-
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--
P
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--
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L
G
-----
H
A
T
G
-----
R
L
L
L
R
-----
R
P
----------
G
Y
A
L
D
L
D
A
V
L
G
A
C
E
A
N
---
G
T
V
V
E
I
--
N
A
N
A
A
R
-----------------------------------------------------------------------------------
26
HHSearch
59.82
17%
-7
- C9 -
-
3B0X
-
?
A:
[370-524]
---------------------------------
A
V
T
D
H
S
P
A
V
R
V
A
------------
G
---
G
P
--
S
P
E
E
A
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R
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G
E
I
R
R
F
N
E
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H
G-
P
P
-
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A
E
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--
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-----------
L
D
Y
P
D
W
----
V
L
---
R
--
E
L
D
L
V
L
V
S
V
H
S
R
F
----
N
--------------------------
L
P
----
K
A
D
Q
T
--------
K
R
L
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K
A
L
E
-
N
--
P
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--
V
H
V
L
A
-----
H
P
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A
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L
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G
R
-----
R
A
----------
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A
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A
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E
K
---
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E
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--
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G
Y
Y
D
R
------------
M
D
L
P
---------
D
D
L
A
R
M
A
Y
G
M
G
L
W
I
--------------------------------------------
28
HHSearch
59.48
20%
-45
- C9 -
-
2W9M
-
?
B:
[360-494]
---------------------------------
G
T
A
D
H
S
R
A
A
Y
Y
A
------------
N
---
G
L
--
T
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E
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-
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D-
G
-
S
-----------
L
D
F
P
D
D
----
V
L
G
-----
E
L
D
Y
V
V
V
S
V
H
S
N
F
----
T
--------------------------
L
----
D
A
A
R
Q
T
--------
E
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R
A
V
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-
H
--
P
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--
V
T
V
L
G
-----
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A
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G
-----
R
L
L
L
R
-----
R
P
----------
G
Y
A
L
D
L
D
A
V
L
G
A
C
E
A
N
---
G
T
V
V
E
I
--
N
A
N
A
A
R
-----------------------------------------------------------------------------------
21
HHSearch
56.23
13%
-103
- C9 -
-
3WYZ
1
RNP3_THEKO
A:
[35-174]
---------------------------------
V
F
T
K
K
L
V
L
E
D
-----------------------
P
P
D
W
G
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L
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E
L
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G
K
Y
--
G
---
K
-
V
A
L
L
L
V
T
R
K
----------------
P
S
L
I
R
E
----
V
K
S
-----
R
N
L
K
A
L
L
Y
V
Q
G
G
D
-----------------------------------------
M
--------
R
I
N
R
M
A
I
E
-
S
---
G
--
V
D
A
L
I
-----
S
P
W
F
-----
G
R
K
D
P
-----
G
------------
F
D
---
H
T
L
A
G
M
A
A
R
R
---
G
V
A
I
G
F
--
S
L
S
P
L
L
N
-
A
N
P
Y
G
R
A
Q
I
-
L
R
F
M
---------
M
K
T
W
Q
L
V
K
K
Y
R
V
P
R
F
-------------------------------------------
25
HHSearch
53.48
15%
-28
- C9 -
-
1M65
-
YCDX_ECOLI
A:
[65-187]
--------------------------------------------------------------------------------------
G
V
-
G
I
L
R
G
I
E
A
N
I
K
N
VD
G
-
E
-----------
I
D
C
S
G
K
----
M
F
---
D
--
S
L
D
L
I
I
A
G
F
H
E
P
V
-----------------------
F
--------
A
-
P
H
D
K
A
T
N
T
--------
Q
A
M
I
A
T
I
A
-
S
--
G
N
--
V
H
I
I
S
-----
H
P
G
N
-----
P
K
Y
E
---------------------
I
D
V
K
A
V
A
E
A
A
A
K
H
---
Q
V
A
L
E
I
--
N
N
S
S
----------------
N
C
---------
R
E
V
A
A
A
V
R
D
A
G
G
W
V
--------------------------------------------
23
HHSearch
53.46
14%
-5
- C9 -
-
2WJE
-
CPSB_STRPN
A:
[42-198]
---------------------------------
V
S
T
S
H
R
R
K
G
M
F
-----------------
E
T
--
P
E
E
K
I
A
E
N
F
L
Q
V
R
E
I
A
K
E
V
AS
D
L
-
V
I
A
Y
G
A
E
I
Y
Y
T
P
--
D
-
V
-----------
L
D
K
L
E
K
KRIP
T
L
N
D
-
S
--
R
Y
A
L
I
E
F
S
M
N
T
--------------------------------------
P
Y
R
D
I
H
--------
S
A
L
S
K
I
L
M
-
L
--
G
I
--
T
P
V
I
A
-----
H
I
E
R
-----
Y
D
A
L
E
---------------------
N
N
E
K
R
V
R
E
L
I
D
M
---
G
C
Y
T
Q
V
--
N
S
S
H
V
L
K
-
P
-
K
LF---
G
E
R
Y
K
F
M
--------
K
K
R
A
Q
Y
F
L
E
Q
D
L
V
H
--------------------------------------------
20
HHSearch
50.76
11%
-110
- C9 -
-
1V77
-
RNP3_PYRHO
A:
[31-163]
---------------------------------
V
V
S
I
K
F
N
E
E
V
-----------------------------
D
K
E
K
L
R
E
A
R
K
E
Y
--
G
K
-
V
---
A
I
L
L
S
N
P
K
----------------
P
S
L
V
R
D
----
T
V
Q
K
-
F
--
K
S
Y
--
L
I
Y
V
E
S
N
---------------------------------
D
--------
L
--------
R
V
I
R
Y
S
I
E
-
K
---
G
--
V
D
A
I
I
-----
S
P
W
V
-----
N
R
K
D
P
-----------------
G
I
D
---
H
V
L
A
K
L
M
V
K
K
---
N
V
A
L
G
F
--
S
L
R
P
L
L
Y
-
S
N
P
Y
E
R
A
N
L
-
L
R
F
M
---------
M
K
A
W
K
L
V
E
K
Y
K
V
R
R
--------------------------------------------
24
HHSearch
50.74
15%
-37
- C9 -
-
1PB0
-
YCDX_ECOLI
A:
[65-187]
--------------------------------------------------------------------------------------
G
V
-
G
I
L
R
G
I
E
A
N
I
K
N
VD
G
-
E
-----------
I
D
C
S
G
K
----
M
F
---
D
--
S
L
D
L
I
I
A
G
F
H
E
P
V
-----------------------
F
--------
A
-
P
H
D
K
A
T
N
T
--------
Q
A
M
I
A
T
I
A
-
S
--
G
N
--
V
H
I
I
S
-----
H
P
G
N
-----
P
K
Y
E
---------------------
I
D
V
K
A
V
A
E
A
A
A
K
H
---
Q
V
A
L
E
I
--
N
----
L
H
-
S
-----------
N
C
---------
R
E
V
A
A
A
V
R
D
A
G
G
W
V
--------------------------------------------
31
HHSearch
50.57
11%
-78
- C9 -
-
2HNH
-
DPO3A_ECOLI
A:
[40-196]
---------------------------------
A
I
T
D
F
T
N
L
C
G
-----------------------------
L
V
K
F
Y
G
A
G
H
G
A
---
G
I
-
K
P
I
V
G
A
D
F
N
V
Q
C
--
D
-
L
-----------
L
-----------
G
D
-
E
--
L
T
H
L
T
V
L
A
A
N
N
T
G
Y
---
Q
----
N
------------
L
T
------
L
-
L
I
S
K
A
Y
Q
R
G
Y
GAA
G
P
I
I
D
R
D
W
L
I
E
L
N
-
E
--
G
L
--
I
L
L
S
G
-----
G
R
M
G
D
V
G
R
S
L
L
R
G
N
-----
S
A
-----------
L
V
D
E
C
V
A
F
Y
E
E
H
F
P
D
---
R
Y
F
L
E
L
--
I
R
T
G
R
P
D
---------
E
-
E
S
Y
L
---------
H
A
A
V
E
L
A
E
A
R
G
L
P
V
--------------------------------------------
19
HHSearch
50.37
11%
-101
- C9 -
-
2CZV
2
RNP3_PYRHO
A:
[31-163]
---------------------------------
V
V
S
I
K
F
N
E
E
V
-----------------------------
D
K
E
K
L
R
E
A
R
K
E
Y
--
G
K
-
V
---
A
I
L
L
S
N
P
K
----------------
P
S
L
V
R
D
----
T
V
Q
K
-
F
--
K
S
Y
--
L
I
Y
V
E
S
N
---------------------------------
D
--------
L
--------
R
V
I
R
Y
S
I
E
-
K
---
G
--
V
D
A
I
I
-----
S
P
W
V
-----
N
R
K
D
P
-----------------
G
I
D
---
H
V
L
A
K
L
M
V
K
K
---
N
V
A
L
G
F
--
S
L
R
P
L
L
Y
-
S
N
P
Y
E
R
A
N
L
-
L
R
F
M
---------
M
K
A
W
K
L
V
E
K
Y
K
V
R
R
--------------------------------------------
36
Fugue
49.18
24%
-105
* C5 *
-
1RYJ
-
?
A:
[4-73]
-----------------------------------------------------------------------------
M
V
I
G
M
K
F
--
T
V
-
I
T
D
D
G
K
K
I
L
E
S
G
--
A
-
P
-----------
R
-
R
I
K
D
----
V
L
G
E
-
L
--
E
I
P
I
E
T
V
V
V
K
K
N
G
----
Q
I
---
V
I
-
D
--
E
E
----
E
I
F
------
D
G
D
I
I
E
V
I
R
V
I
Y
--------
G
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
47.64
9%
-51
- C9 -
-
2HPI
-
DPO3A_THEAQ
A:
[43-260]
---------------------------------
A
M
T
D
H
G
N
L
F
G
-----------------------------
A
V
E
F
Y
K
K
A
T
A
M
---
G
V
-
K
P
I
I
G
Y
E
A
Y
V
A
A
--
E
-
S
RFDRKRG
G
Y
F
H
L
T
L
L
A
K
----
D
F
T
G
Y
Q
--
N
L
V
R
L
A
S
R
A
Y
L
E
G
----------------------
F
------------
Y
E
K
P
R
I
D
--------
R
E
I
L
R
E
H
A
-
Q
--
G
L
--
I
A
L
S
G
-----
C
L
G
A
-----
E
I
P
Q
F
-----
I
L
Q
---------
D
R
L
D
L
A
E
A
R
L
N
E
D
L
S
I
FGD
R
F
F
I
E
I
--
Q
N
H
G
L
P
E
---------
Q
-
K
K
V
N
---------
Q
V
L
K
E
F
A
R
K
Y
G
L
G
M
--------------------------------------------
22
HHSearch
45.59
11%
-17
- C9 -
-
3QY7
-
YWQE_BACSU
A:
[38-189]
---------------------------------
I
A
T
P
H
H
N
N
G
V
Y
K
-----------------
N
--
E
P
A
A
V
R
E
A
A
D
Q
L
N
K
R
L
I
K
E
DI
P
L
-
H
V
L
P
G
Q
E
I
R
I
Y
G
--
E
-
V
-----------
E
Q
D
L
A
K
RQ--
L
L
S
L
-
N
--
D
T
K
Y
I
L
I
E
F
P
F
D
------------------------------------
H
V
P
R
Y
A
E
--------
Q
L
F
Y
D
L
Q
L
-
K
--
G
Y
--
I
P
V
I
A
-----
H
P
E
R
-----
N
R
E
I
R
-----
E
----------------
N
P
S
L
L
Y
H
L
V
E
K
---
G
A
A
S
Q
I
--
T
S
G
S
L
A
G
-
I
-
F
-------
G
K
Q
L
---------
K
A
F
S
L
R
L
V
E
A
N
L
I
H
--------------------------------------------