@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1803: (2016-03-28 )
MTFFKKLKDKITQQTDSVSGKFKDGLSKTRGNFSGKINEMVARYRKVDEDFFEELEEILIGADVGFETVMELVDTLRREVQLRNISDPKDVQEVIVEKLVEIYQGDEKEDEALHIEEDGLTVILFVGVNGVGKTTSIGKMAHRFKQEGKKVMLAAGDTFRAGAIDQLEVWGERTGVDVIKQAEGSDPAAVMFDAVQAAKARKADILLCDTAGRLQNKVNLMNELEKVKRVITREIPNAPHEVLLVLDATTGQNAFVQAKQFKETTDVTGIILTKLDGTAKGGIVIAIRNELDIPVKFVGLGEQMDDLQAFDANEYVYGLFADMVDNEK
Atome Classification :
(51 SA)
.........10........20........30..-......40...-..----...50-.....----...---.60........70......-----..80..--------.----.---...--------.90........100.......---------110......-------.-..120.......130.......140.......150........160.......170---.---....-..180.-....--..190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
T
F
F
K
K
L
K
D
K
I
T
Q
Q
T
D
SVSG
K
F
K
D
G
L
S
K
TRGNF-SG
K
I
N
E
M
V
A
R
Y
-
R
K----V
D
E
D
--
F
F
E
E
L
----
E
E
I
---
L
IGAD
V
G
F
E
T
V
M
E
L
V
D
T
L
R
-----
R
E
V
QLR--------N----I---S
D
P
--------
K
D
V
Q
E
V
I
V
E
K
L
V
E
I
YQGDEKE---------D--
E
A
L
H
IE-------E-D
G
L
T
V
I
L
F
V
GVNGVGKT
T
S
I
G
K
M
A
H
R
F
K
QEG
K
K
-
V
M
L
AAGDTFRAGA
I
D
Q
L
E
V
W
GE---R---T
G
V
D
-
V
I
KQAE-GSD
P
--
A
A
V
M
F
D
A
V
Q
A
AKARKA
D
I
L
L
CDTA
G
R
L
Q
N
K
V
N
L
M
N
E
L
E
K
V
K
R
V
I
T
R
EIPNAP
H
E
V
L
L
V
L
DATTGQN
A
F
V
Q
A
K
Q
FKETTDV
T
G
I
I
L
T
KLDGTAKG
G
I
V
I
A
IRNELDI
P
V
K
F
VGLGEQM
D
D
L
Q
AFDAN
E
Y
V
Y
G
L
F
A
D
M
VDNEK
10
PsiBlast_PDB
93.52
52%
-99
- C6 -
1VMA
1
?
A:
[19-306]
---------------------
L
K
K
G
L
Q
K
T
K
E
T
F
-
F
G
R
V
V
K
L
L
-
K
G
-
K
K
----
L
D
D
E
--
T
R
E
E
L
----
E
E
L
---
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
E
-----
E
K
-----------------------
D
--------
G
D
A
L
E
S
L
K
E
I
I
L
E
I
L
N
F
D
T
K
---------------
L
N
V
P
-------
P
-
E
P
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
V
D
E
G
K
S
-
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
---
R
---
V
G
A
T
-
V
I
S
H
S
E
-
G
A
D
P
--
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
S
E
------
23
PsiBlast_CBE
93.49
52%
-100
- C6 -
1VMA
1
?
B:
[19-306]
---------------------
L
K
K
G
L
Q
K
T
K
E
T
F
-
F
G
R
V
V
K
L
L
-
K
G
-
K
K
----
L
D
D
E
--
T
R
E
E
L
----
E
E
L
---
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
E
-----
E
K
-----------------------
D
--------
G
D
A
L
E
S
L
K
E
I
I
L
E
I
L
N
F
D
T
K
---------------
L
N
V
P
-------
P
-
E
P
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
V
D
E
G
K
S
-
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
---
R
---
V
G
A
T
-
V
I
S
H
S
E
-
G
A
D
P
--
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
S
E
------
87
HHSearch
92.98
54%
-94
- C6 -
1VMA
1
?
A:
[13-305]
---------------
M
G
L
F
D
F
L
K
K
G
L
Q
K
T
K
E
T
F
-
F
G
R
V
V
K
L
L
K
G
--
K
K
----
L
D
D
E
--
T
R
E
E
L
----
E
E
L
---
L
I
Q
A
D
V
G
V
E
T
T
E
Y
I
L
E
R
L
E
-----
E
K
D
G
-------------------------------
D
A
L
E
S
L
K
E
I
I
L
E
I
L
N
F
D
T
--------------
K
-
L
N
V
P
-------
P
-
E
P
P
F
V
I
M
V
V
G
V
N
G
T
G
K
T
T
S
C
G
K
L
A
K
M
F
V
D
E
G
K
S
-
V
V
L
A
A
A
D
T
F
R
A
A
A
I
E
Q
L
K
I
W
G
E
---
R
---
V
G
A
T
-
V
I
S
H
S
E
-
G
A
D
P
--
A
A
V
A
F
D
A
V
A
H
A
L
A
R
N
K
D
V
V
I
I
D
T
A
G
R
L
H
T
K
K
N
L
M
E
E
L
R
K
V
H
R
V
V
K
K
K
I
P
D
A
P
H
E
T
L
L
V
I
D
A
T
T
G
Q
N
G
L
V
Q
A
K
I
F
K
E
A
V
N
V
T
G
I
I
L
T
K
L
D
G
T
A
K
G
G
I
T
L
A
I
A
R
E
L
G
I
P
I
K
F
I
G
V
G
E
K
A
E
D
L
R
P
F
D
P
E
A
F
V
E
V
L
L
S
-------
2
PsiBlast_PDB
92.87
50%
-101
- C6 -
2QY9
-
FTSY_ECOLI
A:
[198-494]
--------------------
R
L
K
R
S
L
L
K
T
K
E
N
L
G
S
G
F
I
S
--
L
F
R
G
-
K
K
----
I
D
D
D
--
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
-----
E
G
A
S
R
K
--------
Q
----
L
---
R
D
A
--------
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
---
K
V
---------
D
--
E
P
L
N
V
E
-------
G
-
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
--
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
-------
77
HHSearch
92.67
42%
-111
- C6 -
3B9Q
1
CFTSY_ARATH
A:
[1-302]
-------------------
E
K
V
F
S
G
F
S
K
T
R
E
N
L
-
A
V
-
I
D
E
L
L
L
F
W
N
L
A
----
E
T
D
R
--
V
L
D
E
L
----
E
E
A
---
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
-----
E
D
I
M
S
G
--------
K
----
L
---
K
S
G
--------
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
--
S
K
---------
T
--
E
-
L
Q
L
G
-------
F
-
R
K
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
K
N
E
G
T
K
-
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
---
R
---
T
G
C
E
-
I
V
V
A
E
--
K
A
K
A
--
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
S
-------
1
PsiBlast_PDB
92.39
50%
-103
- C6 -
2YHS
5
FTSY_ECOLI
A:
[197-494]
-------------------
A
R
L
K
R
S
L
L
K
T
K
E
N
L
G
S
G
F
I
S
--
L
F
R
G
-
K
K
----
I
D
D
D
--
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
-----
E
G
A
S
R
K
--------
Q
----
L
---
R
D
A
--------
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
---
K
V
---------
D
--
E
P
L
N
V
E
-------
G
-
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
--
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
-------
12
PsiBlast_PDB
92.19
42%
-109
- C6 -
3B9Q
1
CFTSY_ARATH
A:
[2-302]
--------------------
K
V
F
S
G
F
S
K
T
R
E
N
L
-
A
-
V
I
D
E
L
L
L
F
W
-
N
L
----
A
E
T
D
R
-
V
L
D
E
L
----
E
E
A
---
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
-----
E
D
I
M
S
G
--------
K
----
L
---
K
S
G
--------
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
--
S
K
---------
T
--
E
-
L
Q
L
G
-------
F
-
R
K
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
K
N
E
G
T
K
-
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
---
R
---
T
G
C
E
I
V
V
A
E
---
K
A
K
A
--
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
S
-------
78
HHSearch
92.09
48%
-101
- C6 -
2YHS
5
FTSY_ECOLI
A:
[191-495]
-------------
T
K
E
G
F
F
A
R
L
K
R
S
L
L
K
T
K
E
N
L
-
G
S
G
F
I
S
L
F
R
G
--
K
K
----
I
D
D
D
--
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
-----
E
G
A
S
R
K
--------
Q
----
L
---
R
D
A
--------
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
K
V
D
--------------
E
P
L
N
V
E
-------
G
-
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
--
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
R
------
7
PsiBlast_PDB
91.89
45%
-103
- C6 -
1ZU4
1
FTSY_MYCMS
A:
[10-308]
------------------------
A
M
L
K
S
A
F
N
F
-
S
K
D
I
K
K
L
S
K
K
Y
-
K
Q
----
A
D
D
E
--
F
F
E
E
L
----
E
D
V
---
L
I
Q
T
D
M
G
M
K
M
V
L
K
V
S
N
L
V
R
-----
K
K
T
K
-
R
--------
D
----
T
---
S
-
F
--------
E
N
I
K
D
A
L
V
E
S
L
Y
Q
A
Y
T
D
N
D
W
---------------
Y
R
I
D
FK-----
E
-
N
R
L
N
I
F
M
L
V
G
V
N
G
T
G
K
T
T
S
L
A
K
M
A
N
Y
Y
A
E
L
G
Y
K
-
V
L
I
A
A
A
D
T
F
R
A
G
A
T
Q
Q
L
E
E
W
I
K
T
RL
N
---
N
K
V
D
-
L
V
K
A
N
K
L
N
A
D
P
--
A
S
V
V
F
D
A
I
K
K
A
K
E
Q
N
Y
D
L
L
L
I
D
T
A
G
R
L
Q
N
K
T
N
L
M
A
E
L
E
K
M
N
K
I
I
Q
Q
V
E
K
S
A
P
H
E
V
L
L
V
I
D
A
T
T
G
Q
N
G
V
I
Q
A
E
E
F
S
K
V
A
D
V
S
G
I
I
L
T
K
M
D
S
T
S
K
G
G
I
G
L
A
I
K
E
L
L
N
I
P
I
K
M
I
G
V
G
E
K
V
D
D
L
L
A
F
D
I
D
Q
Y
I
V
H
L
---------
90
HHSearch
91.67
46%
-109
- C6 -
1ZU4
1
FTSY_MYCMS
A:
[31-314]
-----------------------------------------------
Q
----
A
D
D
E
--
F
F
E
E
L
----
E
D
V
---
L
I
Q
T
D
M
G
M
K
M
V
L
K
V
S
N
L
V
R
-----
K
K
T
K
R
D
-----------------
T
S
F
--------
E
N
I
K
D
A
L
V
E
S
L
Y
Q
A
Y
T
D
N
D
W
-------------
Y
R
I
D
F
K
-------
E
-
N
R
L
N
I
F
M
L
V
G
V
N
G
T
G
K
T
T
S
L
A
K
M
A
N
Y
Y
A
E
L
G
Y
K
-
V
L
I
A
A
A
D
T
F
R
A
G
A
T
Q
Q
L
E
E
W
I
K
---
T
RLN
N
K
V
D
-
L
V
K
A
N
K
L
N
A
D
P
--
A
S
V
V
F
D
A
I
K
K
A
K
E
Q
N
Y
D
L
L
L
I
D
T
A
G
R
L
Q
N
K
T
N
L
M
A
E
L
E
K
M
N
K
I
I
Q
Q
V
E
K
S
A
P
H
E
V
L
L
V
I
D
A
T
T
G
Q
N
G
V
I
Q
A
E
E
F
S
K
V
A
D
V
S
G
I
I
L
T
K
M
D
S
T
S
K
G
G
I
G
L
A
I
K
E
L
L
N
I
P
I
K
M
I
G
V
G
E
K
V
D
D
L
L
A
F
D
I
D
Q
Y
I
V
H
L
S
S
G
F
M
Q
---
4
PsiBlast_PDB
91.58
50%
-102
- C6 -
1FTS
-
FTSY_ECOLI
A:
[203-494]
-------------------------
L
L
K
T
K
E
N
L
G
S
G
F
I
S
--
L
F
R
G
-
K
K
----
I
D
D
D
--
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
-----
E
G
A
S
R
K
--------
Q
----
L
---
R
D
A
--------
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
---
A
K
V
---------
D
--
E
P
L
N
V
E
-------
G
-
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
--
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
-------
3
PsiBlast_PDB
91.57
50%
-102
- C6 -
2XXA
3
FTSY_ECOLI
B:
[20-299]
-------------------------------------
I
S
--
L
F
R
G
-
K
K
----
I
D
D
D
--
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
-----
E
G
A
S
R
K
--------
Q
----
L
---
R
D
A
--------
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
---
K
V
---------
D
--
E
P
L
N
V
E
-------
G
-
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
--
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
-------
22
PsiBlast_CBE
91.55
51%
-108
- C6 -
4C7O
5
FTSY_ECOLI
D:
[2-275]
----------------------------------------------
K
K
----
I
D
D
D
--
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
-----
E
G
A
S
R
K
--------
Q
----
L
---
R
D
A
--------
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
---
K
V
---------
D
--
E
P
L
N
V
E
-------
G
-
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
--
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
-------
21
PsiBlast_CBE
91.30
50%
-102
- C6 -
2XXA
3
FTSY_ECOLI
D:
[20-299]
-------------------------------------
I
S
--
L
F
R
G
-
K
K
----
I
D
D
D
--
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
-----
E
G
A
S
R
K
--------
Q
----
L
---
R
D
A
--------
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
---
K
V
---------
D
--
E
P
L
N
V
E
-------
G
-
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
--
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
-------
8
PsiBlast_PDB
90.64
45%
-102
- C6 -
1ZU5
-
FTSY_MYCMS
A:
[101-399]
------------------------
A
M
L
K
S
A
F
N
F
-
S
K
D
I
K
K
L
S
K
K
Y
-
K
Q
----
A
D
D
E
--
F
F
E
E
L
----
E
D
V
---
L
I
Q
T
D
M
G
M
K
M
V
L
K
V
S
N
L
V
R
-----
K
K
T
K
-
R
--------
D
----
T
---
S
-
F
--------
E
N
I
K
D
A
L
V
E
S
L
Y
Q
A
Y
T
D
N
D
W
T
---------
N
--
K
K
Y
R
I
D
FK-----
E
-
N
R
L
N
I
F
M
L
V
G
V
N
G
T
G
K
T
T
S
L
A
K
M
A
N
Y
Y
A
E
L
G
Y
K
-
V
L
I
A
A
A
D
T
F
R
A
G
A
T
Q
Q
L
E
E
W
I
K
TRL
N
---
N
K
V
D
-
L
V
K
A
N
K
L
N
A
D
P
--
A
S
V
V
F
D
A
I
K
K
A
K
E
Q
N
Y
D
L
L
L
I
D
T
A
G
R
L
Q
N
K
T
N
L
M
A
E
L
E
K
M
N
K
I
I
Q
Q
V
E
K
S
A
P
H
E
V
L
L
V
I
D
A
T
T
G
Q
N
G
V
I
Q
A
E
E
F
S
K
V
A
D
V
S
G
I
I
L
T
K
M
D
S
T
S
K
G
G
I
G
L
A
I
K
E
L
L
N
I
P
I
K
M
I
G
V
G
E
K
V
D
D
L
L
A
F
D
I
D
Q
Y
I
V
H
L
---------
5
PsiBlast_PDB
90.51
50%
-102
- C6 -
3ZN8
-
FTSY_ECOLI
D:
[3-294]
-------------------------
L
L
K
T
K
E
N
L
G
S
G
F
I
S
--
L
F
R
G
-
K
K
----
I
D
D
D
--
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
-----
E
G
A
S
R
K
--------
Q
----
L
---
R
D
A
--------
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
---
A
K
V
---------
D
--
E
P
L
N
V
E
-------
G
-
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
--
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
-------
6
PsiBlast_PDB
90.27
51%
-103
- C6 -
4C7O
4
FTSY_ECOLI
B:
[5-275]
-----------------------------------------------------
D
D
D
--
L
F
E
E
L
----
E
E
Q
---
L
L
I
A
D
V
G
V
E
T
T
R
K
I
I
T
N
L
T
-----
E
G
A
S
R
K
--------
Q
----
L
---
R
D
A
--------
E
A
L
Y
G
L
L
K
E
E
M
G
E
I
L
A
---
K
V
---------
D
--
E
P
L
N
V
E
-------
G
-
K
A
P
F
V
I
L
M
V
G
V
N
G
V
G
K
T
T
T
I
G
K
L
A
R
Q
F
E
Q
Q
G
K
S
-
V
M
L
A
A
G
D
T
F
R
A
A
A
V
E
Q
L
Q
V
W
G
Q
---
R
---
N
N
I
P
-
V
I
A
Q
H
T
-
G
A
D
S
--
A
S
V
I
F
D
A
I
Q
A
A
K
A
R
N
I
D
V
L
I
A
D
T
A
G
R
L
Q
N
K
S
H
L
M
E
E
L
K
K
I
V
R
V
M
K
K
L
D
V
E
A
P
H
E
V
M
L
T
I
D
A
S
T
G
Q
N
A
V
S
Q
A
K
L
F
H
E
A
V
G
L
T
G
I
T
L
T
K
L
D
G
T
A
K
G
G
V
I
F
S
V
A
D
Q
F
G
I
P
I
R
Y
I
G
V
G
E
R
I
E
D
L
R
P
F
K
A
D
D
F
I
E
A
L
F
A
-------
76
HHSearch
89.61
41%
-109
- C6 -
2OG2
2
CFTSY_ARATH
A:
[55-359]
----------------
S
D
V
E
K
V
F
S
G
F
S
K
T
R
E
N
L
-
A
V
-
I
D
E
L
L
L
F
W
N
L
A
----
E
T
D
R
--
V
L
D
E
L
----
E
E
A
---
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
-----
E
D
I
M
S
G
--------
K
----
L
---
K
S
G
--------
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
K
---------------
T
E
L
Q
L
G
-------
F
-
R
K
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
K
N
E
G
T
K
-
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
---
R
---
T
G
C
E
-
I
V
V
A
E
G
D
K
A
K
A
--
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
S
-------
11
PsiBlast_PDB
89.54
41%
-106
- C6 -
2OG2
2
CFTSY_ARATH
A:
[55-359]
----------------
S
D
V
E
K
V
F
S
G
F
S
K
T
R
E
N
L
-
A
-
V
I
D
E
L
L
L
F
W
-
N
L
----
A
E
T
D
R
-
V
L
D
E
L
----
E
E
A
---
L
L
V
S
D
F
G
P
K
I
T
V
R
I
V
E
R
L
R
-----
E
D
I
M
S
G
--------
K
----
L
---
K
S
G
--------
S
E
I
K
D
A
L
K
E
S
V
L
E
M
L
A
K
K
------------
T
--
E
-
L
Q
L
G
-------
F
-
R
K
P
A
V
I
M
I
V
G
V
N
G
G
G
K
T
T
S
L
G
K
L
A
H
R
L
K
N
E
G
T
K
-
V
L
M
A
A
G
D
T
F
R
A
A
A
S
D
Q
L
E
I
W
A
E
---
R
---
T
G
C
E
I
V
V
A
E
G
D
-
K
A
K
A
--
A
T
V
L
S
K
A
V
K
R
G
K
E
E
G
Y
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
S
L
M
E
E
L
I
A
C
K
K
A
V
G
K
I
V
S
G
A
P
N
E
I
L
L
V
L
D
G
N
T
G
L
N
M
L
P
Q
A
R
E
F
N
E
V
V
G
I
T
G
L
I
L
T
K
L
D
G
S
A
R
G
G
C
V
V
S
V
V
E
E
L
G
I
P
V
K
F
I
G
V
G
E
A
V
E
D
L
Q
P
F
D
P
E
A
F
V
N
A
I
F
S
-------
9
PsiBlast_PDB
88.42
46%
-108
- C6 -
4AK9
-
?
A:
[86-382]
-----------------------
S
G
F
S
K
T
R
E
N
L
-
A
-
V
V
D
E
L
L
T
-
Y
-
W
N
----
L
D
E
S
E
S
I
L
D
E
L
----
E
E
V
---
L
L
V
S
D
F
G
P
K
T
A
L
K
I
V
D
T
I
R
-----
K
D
I
L
A
G
--------
R
----
L
---
K
S
G
--------
P
Q
I
K
E
A
L
K
K
N
I
F
K
L
L
T
E
R
V
T
T
---------
T
--
E
-
L
Q
L
G
-------
N
-
S
R
P
A
V
L
M
I
V
G
V
N
G
G
G
K
T
T
T
L
G
K
L
A
N
R
F
K
K
E
G
V
K
-
V
L
M
A
A
G
D
T
--
A
A
A
G
E
Q
L
E
V
W
A
Q
---
R
---
T
G
S
E
-
I
V
-
M
A
-----
P
R
P
A
A
V
L
S
Q
A
V
R
R
A
V
E
E
D
F
D
V
V
L
C
D
T
S
G
R
L
H
T
N
Y
N
L
M
E
E
L
R
G
C
K
R
A
V
S
K
A
L
S
S
A
P
N
E
V
L
L
V
L
D
G
T
T
G
L
N
M
L
A
Q
A
R
E
F
N
Q
V
I
G
V
T
G
F
I
L
T
K
L
D
G
T
A
R
G
G
C
V
V
S
V
V
D
E
L
S
I
P
V
K
F
V
G
V
G
E
G
I
D
D
L
Q
P
F
D
A
Q
S
F
V
D
A
L
F
--------
91
HHSearch
88.20
49%
-103
- C6 -
1RJ9
3
FTSY_THEAQ
A:
[27-303]
----------------------------------------------------
N
L
E
E
--
V
L
E
E
L
----
E
M
A
---
L
L
A
A
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
-----
A
S
G
R
------------------------------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
R
A
T
-------
L
--
R
K
L
G
F
N
P
Q
KPKPV
E
-
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
Q
G
P
E
-
G
T
D
S
--
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
-------
16
PsiBlast_PDB
84.38
49%
-103
- C6 -
1OKK
8
FTSY_THEAQ
D:
[42-302]
-----------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
------------------------
A
---
S
G
R
--------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
--------------------
P
V
-------
E
-
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
Q
G
P
E
-
G
T
D
P
--
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
-------
18
PsiBlast_PDB
83.61
49%
-101
- C6 -
2J7P
7
FTSY_THEAQ
D:
[22-282]
-----------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
------------------------
A
---
S
G
R
--------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
-------------------
K
P
V
-------
E
-
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
Q
G
P
E
-
G
T
D
P
--
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
-------
15
PsiBlast_PDB
83.48
49%
-99
- C6 -
2Q9C
8
FTSY_THEAQ
A:
[43-304]
-----------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
------------------------
A
---
S
G
R
--------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
R
A
T
L
R
K
L
GFN
P
--
Q
K
P
K
P
V
-------
E
-
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
Q
G
P
E
-
G
T
D
P
--
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
D
------
20
PsiBlast_PDB
83.46
49%
-108
- C6 -
2IYL
3
FTSY_THEAQ
D:
[23-284]
-----------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
------------------------
A
---
S
G
R
--------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
---ATLRKLGFN
P
--
Q
K
--
P
V
-------
E
-
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
------
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
Q
G
P
E
-
G
T
D
P
--
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
--
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
D
------
27
PsiBlast_CBE
82.44
49%
-100
- C6 -
2J7P
9
FTSY_THEAQ
E:
[22-282]
-----------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
------------------------
A
---
S
G
R
--------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
--------------------
P
V
-------
E
-
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
Q
G
P
E
-
G
T
D
P
--
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
-------
30
PsiBlast_CBE
82.35
48%
-96
- C6 -
1RJ9
3
FTSY_THEAQ
A:
[43-303]
-----------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
------------------------
A
---
S
G
R
--------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
R
A
T
L
R
K
L
G
F
N
P
--
Q
K
P
K
P
V
-------
E
-
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
Q
G
P
E
-
G
T
D
S
--
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
-------
14
PsiBlast_PDB
81.20
49%
-97
- C6 -
2Q9B
12
FTSY_THEAQ
A:
[43-303]
-----------------------------------------------------------------------------
D
V
G
L
S
A
T
E
E
I
L
Q
E
V
R
------------------------
A
---
S
G
R
--------
K
D
L
K
E
A
V
K
E
K
L
V
G
M
L
E
P
D
E
R
R
A
T
L
R
K
L
GFN
P
--
Q
K
P
K
P
V
-------
E
-
P
K
G
R
V
V
L
V
V
G
V
N
G
V
G
K
T
T
T
I
A
K
L
G
R
Y
Y
Q
N
L
G
K
K
-
V
M
F
C
A
G
D
T
F
R
A
A
G
G
T
Q
L
S
E
W
G
K
---
R
---
L
S
I
P
-
V
I
Q
G
P
E
-
G
T
D
P
--
A
A
L
A
Y
D
A
V
Q
A
M
K
A
R
G
Y
D
L
L
F
V
D
T
A
G
R
L
H
T
K
H
N
L
M
E
E
L
K
K
V
K
R
A
I
A
K
A
D
P
E
E
P
K
E
V
W
L
V
L
D
A
V
T
G
Q
N
G
L
E
Q
A
K
K
F
H
E
A
V
G
L
T
G
V
I
V
T
K
L
D
G
T
A
K
G
G
V
L
I
P
I
V
R
T
L
K
V
P
I
K
F
V
G
V
G
E
G
P
D
D
L
Q
P
F
D
P
E
A
F
V
E
A
L
L
E
-------
35
PsiBlast_CBE
80.05
35%
-95
- C6 -
3DM5
9
SRP54_PYRFU
B:
[4-314]
-----------------------
D
N
L
G
K
A
L
A
N
T
-
L
K
K
I
----
A
R
A
-
S
S
----
V
D
E
A
--
L
I
K
E
L
V
R
D
I
Q
R
A
---
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
---------
R
E
I
Q
R
R
A
L
E
EKPPA
G
----
I
---
S
K
K
--------
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
K
--------------
P
I
E
I
K
-------
E
-
K
P
-
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
R
G
Y
K
-
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
---
R
---
Y
H
I
E
-
V
F
G
N
P
Q
-
E
K
D
A
--
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
-
M
K
Q
I
S
N
V
I
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
--------
82
HHSearch
79.01
42%
-94
- C6 -
3E70
3
?
C:
[50-324]
-----------------------------------------------
K
----
D
V
D
K
--
A
L
D
E
L
----
E
I
D
---
L
L
E
A
D
V
A
L
E
V
V
D
A
L
R
E
K
I
K
-----
Q
K
L
V
G
K
--------
K
----
V
RIG--
G
--------
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
R
I
---------
D
LI
E
E
I
R
K
--------
A
-
E
K
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
H
G
F
S
-
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
---
R
---
I
G
V
K
-
V
I
K
H
S
Y
-
G
A
D
P
--
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
------
T
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
-------
36
PsiBlast_CBE
78.09
35%
-97
- C6 -
3DM5
10
SRP54_PYRFU
A:
[4-313]
-----------------------
D
N
L
G
K
A
L
A
N
T
-
L
K
K
I
----
A
R
A
-
S
S
----
V
D
E
A
--
L
I
K
E
L
V
R
D
I
Q
R
A
---
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
---------
R
E
I
Q
R
R
A
L
E
EKPPA
G
----
I
---
S
K
K
--------
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
K
--------------
P
I
E
I
K
-------
E
-
K
P
-
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
R
G
Y
K
-
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
---
R
---
Y
H
I
E
-
V
F
G
N
P
Q
-
E
K
D
A
--
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
N
V
I
H
------
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
--------
61
PsiBlast_CBE
77.51
33%
-88
- C6 -
4C7O
5
SRP54_ECOLI
C:
[5-288]
---------------------
L
T
D
R
L
S
R
T
L
R
N
I
-
S
G
-------
R
G
-
R
L
----
T
E
D
N
--
V
K
D
T
L
----
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
-
K
--------
S
----
L
---
T
P
G
--------
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
---
E
E
---------
N
--
Q
T
L
N
L
A
-------
A
-
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
---
Q
---
V
G
V
D
-
F
F
P
S
D
V
-
G
Q
K
P
--
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
S
I
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
---------------
31
PsiBlast_CBE
76.59
41%
-93
- C6 -
3E70
3
?
C:
[56-324]
-----------------------------------------------------------
L
D
E
L
----
E
I
D
---
L
L
E
A
D
V
A
----
L
E
V
V
D
A
L
R
-----
E
K
I
K
Q
K
--------
L
----
V
---
G
K
K
VRIGG---
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
R
I
---------
D
--
L
I
E
E
I
R
-------
K
A
E
K
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
H
G
F
S
-
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
---
R
---
I
G
V
K
-
V
I
K
H
S
Y
-
G
A
D
P
--
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
------
T
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
-------
86
HHSearch
76.41
34%
-97
- C6 -
3DM5
10
SRP54_PYRFU
A:
[25-316]
----------------------------------------------
E
A
----
L
I
K
E
--
L
V
R
D
I
----
Q
R
A
---
L
I
Q
A
D
V
N
V
R
L
V
L
Q
L
T
R
E
I
Q
-----
R
R
A
L
E
E
--------
K
PPAG
I
---
S
K
K
--------
E
H
I
I
K
I
V
Y
E
E
L
T
K
F
L
G
T
E
A
--------------
K
P
I
E
I
--------
K
-
E
K
P
T
I
L
L
M
V
G
I
Q
G
S
G
K
T
T
T
V
A
K
L
A
R
Y
F
Q
K
R
G
Y
K
-
V
G
V
V
C
S
D
T
W
R
P
G
A
Y
H
Q
L
R
Q
L
L
D
---
R
---
Y
H
I
E
-
V
F
G
N
P
Q
-
E
K
D
A
--
I
K
L
A
K
E
G
V
D
Y
F
K
S
K
G
V
D
I
I
I
V
D
T
A
G
R
H
K
E
D
K
A
L
I
E
E
M
K
Q
I
S
N
V
I
------
H
P
H
E
V
I
L
V
I
D
G
T
I
G
Q
Q
A
Y
N
Q
A
L
A
F
K
E
A
T
P
I
G
S
I
I
V
T
K
L
D
G
S
A
K
G
G
G
A
L
S
A
V
A
A
T
G
A
P
I
K
F
I
G
T
G
E
K
I
D
D
I
E
P
F
D
P
P
R
F
V
S
R
L
L
G
L
G
-----
33
PsiBlast_CBE
76.08
41%
-95
- C6 -
3DMD
4
?
B:
[56-324]
-----------------------------------------------------------
L
D
E
L
----
E
I
D
---
L
L
E
A
D
V
A
----
L
E
V
V
D
A
L
R
-----
E
K
I
K
Q
K
--------
L
----
V
---
G
K
K
V
R
IGTD
K
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
R
I
---------
D
--
L
I
E
E
I
R
-------
K
A
E
K
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
H
G
F
S
-
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
---
R
---
I
G
V
K
-
V
I
K
H
S
Y
-
G
A
D
P
--
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
------
T
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
-------
59
PsiBlast_CBE
75.94
34%
-84
- C6 -
1RJ9
3
SRP54_THEAQ
B:
[14-282]
------------------------------------------
G
R
L
-
R
G
RGRI
T
E
E
D
--
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
-----
E
E
A
L
G
K
--------
Q
----
V
---
L
E
S
--------
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
---------
E
--
A
R
L
P
V
L
-------
K
-
D
-
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
E
V
M
D
-
G
E
S
P
--
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
------------------
45
PsiBlast_CBE
75.45
34%
-92
- C6 -
2J7P
7
SRP54_THEAQ
B:
[4-282]
-------------------------------
Q
L
-
S
A
R
L
Q
E
A
I
G
R
L
-
R
G
RGRI
T
E
E
D
--
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
-----
E
E
A
L
G
K
--------
Q
----
V
---
L
E
S
--------
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
---------
E
--
A
R
L
P
V
L
-------
K
-
D
-
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
E
V
M
D
-
G
E
S
P
--
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
------------------
46
PsiBlast_CBE
75.25
34%
-87
- C6 -
2J7P
10
SRP54_THEAQ
A:
[4-282]
-------------------------------
Q
L
-
S
A
R
L
Q
E
A
I
G
R
L
-
R
G
RGRI
T
E
E
D
--
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
-----
E
E
A
L
G
K
--------
Q
----
V
---
L
E
S
--------
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
---------
E
--
A
R
L
P
V
L
-------
K
-
D
-
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
E
V
M
D
-
G
E
S
P
--
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
------------------
32
PsiBlast_CBE
75.24
41%
-95
- C6 -
3DMD
7
?
C:
[56-324]
-----------------------------------------------------------
L
D
E
L
----
E
I
D
---
L
L
E
A
D
V
A
----
L
E
V
V
D
A
L
R
-----
E
K
I
K
Q
K
--------
L
----
V
---
G
K
K
V
R
IGTDK
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
R
I
---------
D
--
L
I
E
E
I
R
-------
K
A
E
K
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
H
G
F
S
-
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
---
R
---
I
G
V
K
-
V
I
K
H
S
Y
-
G
A
D
P
--
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
------
T
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
-------
43
PsiBlast_CBE
74.62
34%
-91
- C6 -
3NG1
6
SRP54_THEAQ
B:
[4-282]
-------------------------------
Q
L
-
S
A
R
L
Q
E
A
I
G
R
L
-
R
G
RGRI
T
E
E
D
--
L
K
A
T
L
----
R
E
I
RRA
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
-----
E
E
A
L
G
K
--------
Q
----
V
---
L
E
S
--------
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
---------
E
--
A
R
L
P
V
L
-------
K
-
D
-
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
E
V
M
D
-
G
E
S
P
--
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
------------------
34
PsiBlast_CBE
74.53
41%
-93
- C6 -
3DMD
6
?
A:
[56-324]
-----------------------------------------------------------
L
D
E
L
----
E
I
D
---
L
L
E
A
D
V
A
----
L
E
V
V
D
A
L
R
-----
E
K
I
K
Q
K
--------
L
----
V
---
G
K
K
V
R
IGTD
K
G
K
I
I
E
E
A
V
K
E
A
V
S
E
I
L
E
T
S
R
R
I
---------
D
--
L
I
E
E
I
R
-------
K
A
E
K
P
Y
V
I
M
F
V
G
F
N
G
S
G
K
T
T
T
I
A
K
L
A
N
W
L
K
N
H
G
F
S
-
V
V
I
A
A
S
D
T
F
R
A
G
A
I
E
Q
L
E
E
H
A
K
---
R
---
I
G
V
K
-
V
I
K
H
S
Y
-
G
A
D
P
--
A
A
V
A
Y
D
A
I
Q
H
A
K
A
R
G
I
D
V
V
L
I
D
T
A
G
R
S
E
T
N
R
N
L
M
D
E
M
K
K
I
A
R
V
------
T
K
P
N
L
V
I
F
V
G
D
A
L
A
G
N
A
I
V
E
Q
A
R
Q
F
N
E
A
V
K
I
D
G
I
I
L
T
K
L
D
A
D
A
R
G
G
A
A
L
S
I
S
Y
V
I
D
A
P
I
L
F
V
G
V
G
Q
G
Y
D
D
L
R
P
F
E
K
E
W
F
L
E
R
I
F
G
-------
44
PsiBlast_CBE
74.46
34%
-91
- C6 -
3NG1
5
SRP54_THEAQ
A:
[4-282]
-------------------------------
Q
L
-
S
A
R
L
Q
E
A
I
G
R
L
-
R
G
RGRI
T
E
E
D
--
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
-----
E
E
A
L
G
K
--------
Q
----
V
---
L
E
S
--------
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
---------
E
--
A
R
L
P
V
L
-------
K
-
D
-
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
E
V
M
D
-
G
E
S
P
--
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
------------------
62
PsiBlast_CBE
74.33
33%
-86
- C6 -
4C7O
4
SRP54_ECOLI
A:
[5-288]
---------------------
L
T
D
R
L
S
R
T
L
R
N
I
-
S
G
-------
R
G
-
R
L
----
T
E
D
N
--
V
K
D
T
L
----
R
E
V
R
M
A
L
L
E
A
D
V
A
L
P
V
V
R
E
F
I
N
R
V
K
E
K
A
V
G
H
E
V
N
-
K
--------
S
----
L
---
T
P
G
--------
Q
E
F
V
K
I
V
R
N
E
L
V
A
A
M
G
---
E
E
---------
N
--
Q
T
L
N
L
A
-------
A
-
Q
P
P
A
V
V
L
M
A
G
L
Q
G
A
G
K
T
T
S
V
G
K
L
G
K
F
L
R
E
K
H
K
K
K
V
L
V
V
S
A
D
V
Y
R
P
A
A
I
K
Q
L
E
T
L
A
E
---
Q
---
V
G
V
D
-
F
F
P
S
D
V
-
G
Q
K
P
--
V
D
I
V
N
A
A
L
K
E
A
K
L
K
F
Y
D
V
L
L
V
D
T
A
G
R
L
H
V
D
E
A
M
M
D
E
I
K
Q
V
H
A
S
I
N
------
P
V
E
T
L
F
V
V
D
A
M
T
G
Q
D
A
A
N
T
A
K
A
F
N
E
A
L
P
L
T
G
V
V
L
T
K
V
D
G
D
A
R
G
G
A
A
L
S
I
R
H
I
T
G
K
P
I
K
F
L
G
V
G
E
K
T
E
A
L
E
P
F
H
P
D
---------------
51
PsiBlast_CBE
74.22
34%
-89
- C6 -
1NG1
12
SRP54_THEAQ
A:
[4-282]
-------------------------------
Q
L
-
S
A
R
L
Q
E
A
I
G
R
L
-
R
G
RGRI
T
E
E
D
--
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
-----
E
E
A
L
G
K
--------
Q
----
V
---
L
E
S
--------
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
---------
E
--
A
R
L
P
V
L
-------
K
-
D
-
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
E
V
M
D
-
G
E
S
P
--
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
------------------
40
PsiBlast_CBE
74.08
34%
-93
- C6 -
1JPN
4
SRP54_THEAQ
B:
[4-282]
-------------------------------
Q
L
-
S
A
R
L
Q
E
A
I
G
R
L
-
R
G
RGRI
T
E
E
D
--
L
K
A
T
L
----
R
E
I
RRA
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
-----
E
E
A
L
G
K
--------
Q
----
V
---
L
E
S
--------
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
---------
E
--
A
R
L
P
V
L
-------
K
-
D
-
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
E
V
M
D
-
G
E
S
P
--
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
------------------
42
PsiBlast_CBE
73.88
34%
-91
- C6 -
1JPJ
1
SRP54_THEAQ
A:
[4-282]
-------------------------------
Q
L
-
S
A
R
L
Q
E
A
I
G
R
L
-
R
G
RGRI
T
E
E
D
--
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
-----
E
E
A
L
G
K
--------
Q
----
V
---
L
E
S
--------
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
---------
E
--
A
R
L
P
V
L
-------
K
-
D
-
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
E
V
M
D
-
G
E
S
P
--
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
------------------
58
PsiBlast_CBE
73.86
34%
-91
- C6 -
2NG1
4
SRP54_THEAQ
A:
[3-281]
-------------------------------
Q
L
-
S
A
R
L
Q
E
A
I
G
R
L
-
R
G
RGRI
T
E
E
D
--
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
T
R
D
F
V
E
R
V
R
-----
E
E
A
L
G
K
--------
Q
----
V
---
L
E
S
--------
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
---------
E
--
A
R
L
P
V
L
-------
K
-
D
-
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
E
V
M
D
-
G
E
S
P
--
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
------------------
50
PsiBlast_CBE
73.82
34%
-86
- C6 -
1OKK
16
SRP54_THEAQ
A:
[4-282]
-------------------------------
Q
L
-
S
A
R
L
Q
E
A
I
G
R
L
-
R
G
RGRI
T
E
E
D
--
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
-----
E
E
A
L
G
K
--------
Q
----
V
---
L
E
S
--------
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
---------
E
--
A
R
L
P
V
L
-------
K
-
D
-
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
E
V
M
D
-
G
E
S
P
--
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
------------------
56
PsiBlast_CBE
73.81
34%
-88
- C6 -
1O87
7
SRP54_THEAQ
B:
[4-282]
-------------------------------
Q
L
-
S
A
R
L
Q
E
A
I
G
R
L
-
R
G
RGRI
T
E
E
D
--
L
K
A
T
L
----
R
E
I
RRA
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
-----
E
E
A
L
G
K
--------
Q
----
V
---
L
E
S
--------
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
---------
E
--
A
R
L
P
V
L
-------
K
-
D
-
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
E
V
M
D
-
G
E
S
P
--
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
------------------
57
PsiBlast_CBE
73.46
34%
-89
* C6 *
1O87
7
SRP54_THEAQ
A:
[4-282]
-------------------------------
Q
L
-
S
A
R
L
Q
E
A
I
G
R
L
-
R
G
RGRI
T
E
E
D
--
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
-----
E
E
A
L
G
K
--------
Q
----
V
---
L
E
S
--------
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
---------
E
--
A
R
L
P
V
L
-------
K
-
D
-
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
E
V
M
D
-
G
E
S
P
--
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
------------------
41
PsiBlast_CBE
73.05
34%
-90
- C6 -
1JPN
4
SRP54_THEAQ
A:
[4-282]
-------------------------------
Q
L
-
S
A
R
L
Q
E
A
I
G
R
L
-
R
G
RGRI
T
E
E
D
--
L
K
A
T
L
----
R
E
I
R
R
A
L
M
D
A
D
V
N
L
E
V
A
R
D
F
V
E
R
V
R
-----
E
E
A
L
G
K
--------
Q
----
V
---
L
E
S
--------
L
T
P
A
E
V
I
L
A
T
V
Y
E
A
L
K
E
A
L
G
G
---------
E
--
A
R
L
P
V
L
-------
K
-
D
-
R
N
L
W
F
L
V
G
L
Q
G
S
G
K
T
T
T
A
A
K
L
A
L
Y
Y
K
G
K
G
R
R
-
P
L
L
V
A
A
D
T
Q
R
P
A
A
R
E
Q
L
R
L
L
G
E
---
K
---
V
G
V
P
-
V
L
E
V
M
D
-
G
E
S
P
--
E
S
I
R
R
R
V
E
E
K
A
R
L
E
A
R
D
L
I
L
V
D
T
A
G
R
L
Q
I
D
E
P
L
M
G
E
L
A
R
L
K
E
V
L
------
G
P
D
E
V
L
L
V
L
D
A
M
T
G
Q
E
A
L
S
V
A
R
A
F
D
E
K
V
G
V
T
G
L
V
L
T
K
L
D
G
D
A
R
G
G
A
A
L
S
A
R
H
V
T
G
K
P
I
Y
F
A
G
V
S
E
K
P
E
G
L
E
P
F
------------------