@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo2391: (2016-04-03 )
MNVLVIGANGKIGRLLVEKLAMEKGFFVRAMVRKAEQVSELEKLGAKPIIADLKKDFHYAYDEIEAVIFTAGSGGHTPASETVNIDQNGAIKAIETAKEKGVRRFIIVSSYGADNPENGPESLAHYLKAKQAADEELKKSGLDYTIVRPVGLSDDPATGKIAEVSGKPKTNIPRADVADFISEALSEKSSFYKTYTIESGDTPIKQFFN
Atome Classification :
(20 SA)
----.........10........20..-.-.--...-.30..---------......----------40---....--.-..---.50...--..--....60.--....-...70......----.---------.80------..-----------------.----------------......90........100.....-...110..-..--.---.---------.-----120--...--......130.......----140.......150...-----------..------.--------.------------160----------.---------------.--.-----.-------.---.-------.-..170-----........180......--.190.....----..200----........-------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----
M
N
V
L
V
IGANG
K
I
G
R
L
L
V
E
K
L
A
ME-K-
G
--
F
F
V
-
R
A
M
V
R
---------
K
A
E
Q
V
S
----------
E
L
---
E
K
LG--A-K
P
---
I
I
-
A
D
L
--
K
K
--
D
F
H
Y
A
Y
D
--
E
I
E
A
-
V
I
F
TAGSGGHT----P---------AS-------
E
T
-----------------
V
----------------NIDQNGAI
K
A
I
E
T
A
K
E
KG-
V
R
R
F
I
-
I
V
S
SYGAD-NP--E---N---------
G
-----
P
----
E
S
L
--
A
H
Y
L
K
A
K
Q
A
A
D
E
E
L
K
K----SGL
D
Y
T
I
V
R
PVGLSDD-----------PA------T--------G------------
K
------------
I
---------------
A
--E-----V-------S---G-------K-PKTN------I
P
R
A
D
V
A
D
F
I
S
E
A
L
S
E
K--SS
F
Y
K
T
Y
T
I----ESG-D----
T
P
I
K
Q
FFN-------------------------------------------------------------------------------
1
PsiBlast_PDB
95.73
48%
-98
- C1 -
3E8X
2
?
A:
[24-227]
------
V
L
V
V
G
A
N
G
K
V
A
R
Y
L
L
S
E
L
K
-
N
-
K
-
G
--
H
E
P
-
V
A
M
V
R
---------
N
E
E
Q
G
P
----------
E
L
---
R
E
R
G
--
A
-
S
D
---
I
V
V
A
N
L
--
E
E
--
D
F
S
H
A
F
A
--
S
I
D
A
-
V
V
F
A
A
G
S
G
P
H
T
----
G
---------
A
D
-------
K
T
-----------------
I
----------------
L
I
D
L
W
G
A
I
K
T
I
Q
E
A
E
K
R
G
-
I
K
R
F
I
-
M
V
S
S
V
G
T
V
-
D
P
--
D
---
Q
---------
G
-----
P
----
M
N
M
--
R
H
Y
L
V
A
K
R
L
A
D
D
E
L
K
R
----
S
S
L
D
Y
T
I
V
R
P
G
P
L
S
N
E
-----------
E
S
------
T
--------
G
------------
K
------------
V
---------------
T
--------
V
-------
S
PHF
S
-------
E
-
I
T
R
S
------
I
T
R
H
D
V
A
K
V
I
A
E
L
V
D
Q
Q
--
H
T
I
G
K
T
F
E
V
----
L
N
G
-
D
----
T
P
I
------------------------------------------------------------------------------------
31
HHSearch
93.92
47%
-96
- C1 -
3E8X
2
?
A:
[22-232]
----
M
R
V
L
V
V
G
A
N
G
K
V
A
R
Y
L
L
S
E
L
K
N
K
---
G
--
H
E
P
-
V
A
M
V
R
---------
N
E
E
Q
G
P
----------
E
L
---
R
E
R
G
--
A
S
D
I
---
V
V
-
A
N
L
--
E
E
--
D
F
S
H
A
F
A
--
S
I
D
A
-
V
V
F
A
A
G
S
G
P
H
T
----
G
---------
A
D
-------
K
T
-----------------
I
----------------
L
I
D
L
W
G
A
I
K
T
I
Q
E
A
E
K
R
G
-
I
K
R
F
I
-
M
V
S
S
V
G
T
V
-
D
P
--
D
---
Q
---------
G
-----
P
----
M
N
M
--
R
H
Y
L
V
A
K
R
L
A
D
D
E
L
K
R
----
S
S
L
D
Y
T
I
V
R
P
G
P
L
S
N
E
-----------
E
S
------
T
--------
G
------------
K
------------
V
---------------
T
--
V
-----
S
-------
P
HF-
S
-------
E
-
I
T
R
S
------
I
T
R
H
D
V
A
K
V
I
A
E
L
V
D
Q
Q
--
H
T
I
G
K
T
F
E
V
----
L
N
G
-
D
----
T
P
I
A
K
V
V
E
-------------------------------------------------------------------------------
6
PsiBlast_PDB
77.15
29%
-80
- C1 -
2Q4B
1
Y5224_ARATH
A:
[6-242]
-----
T
V
L
V
T
G
A
S
G
R
T
G
Q
I
V
Y
K
K
L
K
E
G
-
S
-
D
--
K
F
V
A
K
G
L
V
R
---------
S
A
Q
G
K
----------------
E
K
I
G
GE
A
-
D
V
---
F
I
-
G
D
I
--
T
D
AD
S
I
N
P
A
F
Q
--
G
I
D
A
L
V
I
L
T
S
A
V
P
K
M
K
----
P
--------------------------------------
E
F
I
F
E
D
GQYPE-----
Q
V
D
W
I
G
Q
K
N
Q
I
D
A
A
K
V
A
G
-
V
K
H
I
V
-
V
V
G
S
M
G
G
T
-
N
P
--
D
---
H
---------
P
-----
L
----
N
K
L
GN
G
N
I
L
V
W
K
R
K
A
E
Q
Y
L
A
D
----
S
G
T
P
Y
T
I
I
R
A
G
G
L
L
D
K
-----------
E
G
GVRE
L
L
V
--------
G
------------
K
------------
D
---------------
D
--
E
-----
L
-------
L
---
Q
-------
T
-
D
T
K
T
------
V
P
R
A
D
V
A
E
V
C
I
Q
A
L
L
F
E
--
E
A
K
N
K
A
F
D
L
G
S
K
P
E
G
T
-
S
----
T
P
T
K
D
F
---------------------------------------------------------------------------------
5
PsiBlast_PDB
77.13
29%
-90
- C1 -
2Q46
1
Y5224_ARATH
A:
[6-242]
-----
T
V
L
V
T
G
A
S
G
R
T
G
Q
I
V
Y
K
K
L
K
E
G
-
S
-
D
--
K
F
V
A
K
G
L
V
R
---------
S
A
Q
G
K
----------------
E
K
I
G
GE
A
-
D
V
---
F
I
-
G
D
I
--
T
D
AD
S
I
N
P
A
F
Q
--
G
I
D
A
L
V
I
L
T
S
A
V
P
K
M
K
----
P
---------
G
F
-------
D
P
-----------------
T
K
G
G
R
P
E
F
I
F
EDGQYPE
Q
V
D
W
I
G
Q
K
N
Q
I
D
A
A
K
V
A
G
-
V
K
H
I
V
-
V
V
G
S
M
G
G
T
-
N
P
--
D
---
H
---------
P
-----
L
----
N
K
L
GN
G
N
I
L
V
W
K
R
K
A
E
Q
Y
L
A
D
----
S
G
T
P
Y
T
I
I
R
A
G
G
L
L
D
K
-----------
E
G
GVRE
L
L
V
--------
G
------------
K
------------
D
---------------
D
--
E
-----
L
-------
L
---
Q
-------
T
-
D
T
K
T
------
V
P
R
A
D
V
A
E
V
C
I
Q
A
L
L
F
E
--
E
A
K
N
K
A
F
D
L
G
S
K
P
E
G
T
-
S
----
T
P
T
K
D
F
---------------------------------------------------------------------------------
4
PsiBlast_PDB
76.87
29%
-82
- C1 -
1YBM
1
Y5224_ARATH
A:
[6-242]
-----
T
V
L
V
T
G
A
S
G
R
T
G
Q
I
V
Y
K
K
L
K
E
G
-
S
-
D
--
K
F
V
A
K
G
L
V
R
---------
S
A
Q
G
K
----------------
E
K
I
G
GE
A
-
D
V
---
F
I
-
G
D
I
--
T
D
AD
S
I
N
P
A
F
Q
--
G
I
D
A
L
V
I
L
T
S
A
V
P
K
M
K
----
P
--------------------------------------
E
F
I
F
E
D
GQYPE-----
Q
V
D
W
I
G
Q
K
N
Q
I
D
A
A
K
V
A
G
-
V
K
H
I
V
-
V
V
G
S
M
G
G
T
-
N
P
--
D
---
H
---------
P
-----
L
----
N
K
L
GN
G
N
I
L
V
W
K
R
K
A
E
Q
Y
L
A
D
----
S
G
T
P
Y
T
I
I
R
A
G
G
L
L
D
K
-----------
E
G
GVRE
L
L
V
--------
G
------------
K
------------
D
---------------
D
--
E
-----
L
-------
L
---
Q
-------
T
-
D
T
K
T
------
V
P
R
A
D
V
A
E
V
C
I
Q
A
L
L
F
E
--
E
A
K
N
K
A
F
D
L
G
S
K
P
E
G
T
-
S
----
T
P
T
K
D
F
---------------------------------------------------------------------------------
3
PsiBlast_PDB
76.47
29%
-87
- C1 -
1XQ6
1
Y5224_ARATH
A:
[6-242]
-----
T
V
L
V
T
G
A
S
G
R
T
G
Q
I
V
Y
K
K
L
K
E
G
-
S
-
D
--
K
F
V
A
K
G
L
V
R
---------
S
A
Q
G
K
----------------
E
K
I
G
GE
A
-
D
V
---
F
I
-
G
D
I
--
T
D
AD
S
I
N
P
A
F
Q
--
G
I
D
A
L
V
I
L
T
S
A
V
P
K
M
K
----
P
---------
G
F
-------
D
P
-----------------
T
KGG
R
P
E
F
I
F
E
DGQYPE
Q
V
D
W
I
G
Q
K
N
Q
I
D
A
A
K
V
A
G
-
V
K
H
I
V
-
V
V
G
S
M
G
G
T
-
N
P
--
D
---
H
---------
P
-----
L
----
N
K
L
GN
G
N
I
L
V
W
K
R
K
A
E
Q
Y
L
A
D
----
S
G
T
P
Y
T
I
I
R
A
G
G
L
L
D
K
-----------
E
G
GVRE
L
L
V
--------
G
------------
K
------------
D
---------------
D
--
E
-----
L
-------
L
---
Q
-------
T
-
D
T
K
T
------
V
P
R
A
D
V
A
E
V
C
I
Q
A
L
L
F
E
--
E
A
K
N
K
A
F
D
L
G
S
K
P
E
G
T
-
S
----
T
P
T
K
D
F
---------------------------------------------------------------------------------
34
HHSearch
74.81
29%
-80
- C1 -
1XQ6
1
Y5224_ARATH
A:
[5-243]
----
P
T
V
L
V
T
G
A
S
G
R
T
G
Q
I
V
Y
K
K
L
K
E
G
---
S
DK
F
V
A
-
K
G
L
V
R
---------
S
A
Q
G
K
E
----------
K
I
----
G
G
E
--
A
-
D
V
---
F
I
-
G
D
I
--
T
D
AD
S
I
N
P
A
F
Q
--
G
I
D
A
-
L
V
I
L
T
S
A
V
P
K
M
K---
P
GFDPTKGG
R
P
E
F
I
F
E
DGQ
Y
P
-----------------
E
----------------
Q
V
D
W
I
G
Q
K
N
Q
I
D
A
A
K
V
A
G
-
V
K
H
I
V
-
V
V
G
S
M
G
G
T
-
N
P
--
D
H--
P
---------
L
N----
K
----
L
G
N
--
G
N
I
L
V
W
K
R
K
A
E
Q
Y
L
A
D
----
S
G
T
P
Y
T
I
I
R
A
G
G
L
L
D
K
-----------
E
G
------
G
--------
V
R-----------
E
------------
L
---------------
L
--
V
-----
G
-------
K
DD-
E
L
L
Q
----
T
-
D
T
K
T
------
V
P
R
A
D
V
A
E
V
C
I
Q
A
L
L
F
E
--
E
A
K
N
K
A
F
D
L
----
G
S
K
-
P
EGTS
T
P
T
K
D
F
K
--------------------------------------------------------------------------------
46
HHSearch
70.93
21%
-79
- C1 -
2GAS
-
IFR_MEDSA
A:
[5-239]
----
N
K
I
L
I
L
G
P
T
G
A
I
G
R
H
I
V
W
A
S
I
K
A
---
G
--
N
P
T
-
Y
A
L
V
R
---------
K
T
I
T
A
A
N
P
E
T
K
E
E
L
I
D
N
Y
---
Q
S
L
G
--
V
-
I
L
---
L
E
-
G
D
I
--
N
D
H
E
T
L
V
K
A
I
K
--
Q
V
D
I
-
V
I
C
A
A
G
R
L
L
I
----------------------------------------------------------------
E
D
Q
V
K
I
I
K
A
I
K
E
A
G
N
V
K
K
F
F
--
P
S
E
F
G
L
D
-
V
D
--
R
H--
D
---------
A
-----
V
----
E
P
V
--
R
Q
V
F
E
E
K
A
S
I
R
R
V
I
E
A
----
E
G
V
P
Y
T
Y
L
C
C
H
A
F
T
G
Y
-----------
F
L
------
R
--------
N
------------
L
AQLDATDPPR
D
K
V
---------------
V
--
I
L
----
G
-------
D
G--
N
-------
V
-
K
G
A
Y
------
V
T
E
A
D
V
G
T
F
T
I
R
A
A
N
D
P
--
N
T
L
N
K
A
V
H
I
----
R
L
P
K
N
Y---
L
T
Q
N
E
V
I
A
-------------------------------------------------------------------------------
45
HHSearch
69.28
21%
-76
- C1 -
3WJ7
2
?
A:
[14-254]
----
D
V
T
L
V
T
G
A
T
G
F
V
G
S
A
V
A
R
V
L
E
E
R
---
G
--
H
R
L
-
R
L
L
V
R
---------
P
T
S
D
R
S
----------
N
I
---
A
E
L
N
--
A
-
E
L
---
A
V
-
G
D
L
--
S
D
P
D
T
L
A
P
A
L
K
--
G
V
K
I
-
L
F
H
V
A
A
D
Y
R
L
W
VP--
D
---------
P
E
-------
T
M
-----------------
M
----------------
K
A
N
V
E
G
T
R
N
L
M
L
A
A
L
E
A
G
-
V
E
K
I
I
-
Y
C
S
S
V
A
A
L
-
G
L
R
-
S
DGV
P
---------
A
DETT-
P
VSES
Q
V
I
--
G
I
Y
K
L
S
K
Y
R
A
E
Q
E
V
L
R
L
I
R
E
K
N
L
P
A
I
I
V
N
P
S
T
P
V
G
P
-----------
R
D
------
I
--------
K
------------
P
T
P
----------
T
G
--------------
Q
M
-
I
L
D
C
A
S
G
NMP
A
Y
--
V
---
E
-------
T
-
G
L
N
I
------
V
H
V
D
D
V
A
E
G
H
A
L
A
L
E
R
G
---
K
I
G
E
K
Y
I
L
----
G
G
E
-
N
----
I
M
L
G
D
L
F
R
-------------------------------------------------------------------------------
9
PsiBlast_PDB
68.12
23%
-92
- C1 -
1HE3
2
BLVRB_HUMAN
A:
[6-190]
------
I
A
I
F
G
A
T
G
Q
T
G
-
L
T
T
L
A
Q
A
V
Q
-
A
-
G
--
Y
E
V
-
T
V
L
V
R
---------
D
S
---
S
----------
R
L
---
P
S
E
G
--
P
-
R
P
A
H
V
V
V
-
G
D
V
--
L
Q
A
A
D
V
D
K
T
V
A
--
G
Q
D
A
-
V
I
V
L
L
G
T
R
N
D
L
----
S
---------
P
T
-------
T
V
-----------------
M
----------------
S
---
E
G
A
R
N
I
V
A
A
M
K
A
H
G
-
V
D
K
V
V
A
C
T
S
A
F
L
L
W
-
D
P
--
T
---
K
---------
V
-----
P
----
P
R
L
--
Q
A
V
T
D
D
H
I
R
M
H
K
V
L
R
E
----
S
G
L
K
Y
V
A
V
M
P
P
H
I
G
D
Q
-----------
P
L
------
T
--------
G
------------
A
Y
-----------
T
---------------
V
--
T
-----
L
-------
D
---
G
-------
R
G
P
S
R
V
------
I
S
K
H
D
L
G
H
F
M
L
R
C
L
T
-----------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
67.23
23%
-93
- C1 -
1HE4
2
BLVRB_HUMAN
A:
[6-190]
------
I
A
I
F
G
A
T
G
Q
T
G
-
L
T
T
L
A
Q
A
V
Q
-
A
-
G
--
Y
E
V
-
T
V
L
V
R
---------
D
S
---
S
----------
R
L
---
P
S
E
G
--
P
-
R
P
A
H
V
V
V
-
G
D
V
--
L
Q
A
A
D
V
D
K
T
V
A
--
G
Q
D
A
-
V
I
V
L
L
G
T
R
N
D
L
----
S
---------
P
T
-------
T
V
-----------------
M
----------------
S
---
E
G
A
R
N
I
V
A
A
M
K
A
H
G
-
V
D
K
V
V
A
C
T
S
A
F
L
L
W
-
D
P
--
T
---
K
---------
V
-----
P
----
P
R
L
--
Q
A
V
T
D
D
H
I
R
M
H
K
V
L
R
E
----
S
G
L
K
Y
V
A
V
M
P
P
H
I
G
D
Q
-----------
P
L
------
T
--------
G
------------
A
Y
-----------
T
---------------
V
--
T
-----
L
-------
D
---
G
-------
R
G
P
S
R
V
------
I
S
K
H
D
L
G
H
F
M
L
R
C
L
T
-----------------------------------------------------------------------------------------------------------------
56
Fugue
66.90
26%
-78
- C1 -
1XQ6
1
Y5224_ARATH
A:
[1-253]
SAN
L
P
T
V
L
V
T
G
A
S
G
R
T
G
Q
I
V
Y
K
K
L
K
E
G
S
D
-
K
--
F
V
A
-
K
G
L
V
R
---------
S
A
Q
G
K
E
----------
K
I
---
G
G
-
E
--
A
-
D
V
---
F
I
-
G
D
I
TD
A
D
--
S
I
N
P
A
F
Q
--
G
I
D
A
-
L
V
I
L
T
S
A
V
P
K
M
----
K
---------
P
G
-------
F
D
PTKGG
R
P
E
F
I
F
E
DGQYP
E
----------------
Q
V
D
W
I
G
Q
K
N
Q
I
D
A
A
K
V
A
G
-
V
K
H
I
V
-
V
V
G
S
M
G
G
T
-
N
P
DH
P
---
L
---------
N
-----
K
----
L
G
N
--
G
N
I
L
V
W
K
R
K
A
E
Q
Y
L
A
D
----
S
G
T
P
Y
T
I
I
R
A
G
G
L
L
D
K
-----------
E
G
------
G
--------
V
------------
R
------------
E
---------------
L
--
L
-----
V
-------
G
---
K
-------
D
-
D
E
L
L
Q
T
DTK
T
V
P
R
A
D
V
A
E
V
C
I
Q
A
L
L
F
E
--
E
A
K
N
K
A
F
D
L
----
G
S
K
-
P
----
E
G
T
S
T
P
T
K
D
F
K
A
L
F
S
Q
VTSRF------------------------------------------------------------------
32
HHSearch
66.71
19%
-84
- C1 -
2JL1
6
?
A:
[1-211]
----
F
S
I
A
V
T
G
A
T
G
Q
L
G
G
L
V
I
Q
H
L
L
K
K
-
V
P
A
--
S
Q
I
-
I
A
I
V
R
---------
N
V
E
K
A
S
----------
T
L
---
A
D
Q
G
--
V
-
E
V
---
R
H
-
G
D
Y
--
N
Q
P
E
S
L
Q
K
A
F
A
--
G
V
S
K
-
L
L
F
I
S
G
P
H
Y
D
-------------------------------------------
N
----------------
T
L
L
I
V
Q
H
A
N
V
V
K
A
A
R
D
A
G
-
V
K
H
I
A
-
Y
T
G
Y
A
F
A
E
-
E
-----------------------------
S
I
--
I
P
L
A
H
V
H
L
A
T
E
Y
A
I
R
T
----
T
N
I
P
Y
T
F
L
R
N
A
L
Y
T
D
F
-----------
F
V
------
N
--------
E
GL
R
A
S
T
E
S
G---
A
------------
I
---------------
V
--
T
-----
N
-------
A
G--
S
-------
G
-
I
V
N
S
------
V
T
R
N
E
L
A
L
A
A
A
T
V
L
T
E
E
--
G
H
E
N
K
T
Y
N
L
----
V
S
N
-
Q
P---
W
T
F
D
E
L
A
Q
-------------------------------------------------------------------------------
11
PsiBlast_PDB
66.37
23%
-91
- C1 -
1HE5
2
BLVRB_HUMAN
A:
[6-190]
------
I
A
I
F
G
A
T
G
Q
T
G
-
L
T
T
L
A
Q
A
V
Q
-
A
-
G
--
Y
E
V
-
T
V
L
V
R
---------
D
S
---
S
----------
R
L
---
P
S
E
G
--
P
-
R
P
A
H
V
V
V
-
G
D
V
--
L
Q
A
A
D
V
D
K
T
V
A
--
G
Q
D
A
-
V
I
V
L
L
G
T
R
N
D
L
----
S
---------
P
T
-------
T
V
-----------------
M
----------------
S
---
E
G
A
R
N
I
V
A
A
M
K
A
H
G
-
V
D
K
V
V
A
C
T
S
A
F
L
L
W
-
D
P
--
T
---
K
---------
V
-----
P
----
P
R
L
--
Q
A
V
T
D
D
H
I
R
M
H
K
V
L
R
E
----
S
G
L
K
Y
V
A
V
M
P
P
H
I
G
D
Q
-----------
P
L
------
T
--------
G
------------
A
Y
-----------
T
---------------
V
--
T
-----
L
-------
D
---
G
-------
R
G
P
S
R
V
------
I
S
K
H
D
L
G
H
F
M
L
R
C
L
T
-----------------------------------------------------------------------------------------------------------------
41
HHSearch
66.31
23%
-84
- C1 -
3QVO
1
?
A:
[24-234]
----
K
N
V
L
I
L
G
A
G
G
Q
I
A
R
H
V
I
N
Q
L
A
D
K
---
Q
T-
I
K
Q
-
T
L
F
A
R
---------
Q
P
A
K
I
H
----------
K
P
---
Y
P
T
N
--
S
-
Q
I
---
I
M
-
G
D
V
--
L
N
H
A
A
L
K
Q
A
M
Q
--
G
Q
D
I
-
V
Y
A
N
L
T
G
E
D
---------------------------------------------------------------
L
D
I
Q
A
N
S
V
I
A
A
M
K
A
C
D
-
V
K
R
L
I
-
F
V
L
S
L
G
----------------------------------
I
--
G
E
P
L
K
P
F
R
R
A
A
D
A
I
E
A
----
S
G
L
E
Y
T
I
L
R
P
A
W
L
T
D
E
-----------
D
I
------
I
---------------------
D
------------
Y
---------------
E
--
L
-----
T
S
RN----
E
---
P
-------
F
-
K
G
T
I
------
V
S
R
K
S
V
A
A
L
I
T
D
I
I
D
K
P
E-
K
H
I
G
E
N
I
G
I
----
N
Q
P
-
G
T---
D
G
D
K
P
F
F
M
-------------------------------------------------------------------------------
52
HHSearch
65.32
22%
-66
- C1 -
2C20
2
?
A:
[2-265]
----
N
S
I
L
I
C
G
G
A
G
Y
I
G
S
H
A
V
K
K
L
V
D
E
---
G
--
L
S
V
-
V
V
V
D
N
---------
L
Q
T
G
H
E
----------
D
A
---
I
T
E
G
--
A
-
K
F
---
Y
N
-
G
D
L
--
R
D
K
A
F
L
R
D
V
F
T
Q
E
N
I
E
A
-
V
M
H
F
A
A
D
S
L
V
G
V
S
M
E
K
---------
P
L
-------
Q
Y
-----------------
Y
----------------
N
N
N
V
Y
G
A
L
C
L
L
E
V
M
D
E
F
K
-
V
D
K
F
I
-
F
S
S
T
A
A
T
Y
-
G
E
--
V
---
D
VDL------
I
TEE
T
M
T
----
N
P
T
--
N
T
Y
G
E
T
K
L
A
I
E
K
M
L
H
W
Y
S
Q
A
S
N
L
R
Y
K
I
F
R
Y
F
N
V
A
G
A
-----------
T
P
------
N
--------
G
IIGEDHRPET--
H
------------
L
I
P
L
V
L
Q
V
A
L
GQRE
K
I
M
M
-
F
-----
G
DDYNTPD
G
---
T
-------
C
-
I
R
D
Y
------
I
H
V
E
D
L
V
A
A
H
F
L
G
L
K
D
L
Q
N
G
G
E
S
D
F
Y
N
L
----
G
N
G
-
N
G---
F
S
V
K
E
I
V
D
-------------------------------------------------------------------------------
57
Fugue
65.16
19%
-89
- C1 -
1QYC
-
?
A:
[2-308]
-G
S
R
S
R
I
L
L
I
G
A
T
G
Y
I
G
R
H
V
A
K
A
S
L
D
--
L
-
G
--
H
P
T
-
F
L
L
V
R
ESTASSNS
E
K
A
Q
L
L
E
----------
S
F
---
K
A
S
G
--
A
-
N
I
---
V
H
-
G
S
I
DD
H
A
--
S
L
V
E
A
V
K
--
N
V
D
V
-
V
I
S
T
V
G
----------------------------------------------------------------
S
L
Q
I
E
S
Q
V
N
I
I
K
A
I
K
E
V
G
-
T
V
K
R
F
-
F
P
S
E
F
G
N
D
V
D
N
--
V
---
H
---------
A
-----
V
----
E
P
A
--
K
S
V
F
E
V
K
A
K
V
R
R
A
I
E
A
----
E
G
I
P
Y
T
Y
V
S
S
N
C
F
A
G
Y
FLRSLAQAGLT
A
P
------
P
--------
R
------------
D
------------
K
---------------
V
--
V
-----
I
-------
L
---
G
DGN----
A
-
R
V
V
F
------
V
K
E
E
D
I
G
T
F
T
I
K
A
V
D
D
P
--
R
T
L
N
K
T
L
Y
L
RL--
P
A
N
-
T
----
L
S
L
N
E
L
V
A
L
W
E
K
K
I
D
K
T
L
E
K
A
Y
V
P
E
E
E
V
L
K
L
I
A
D
TPF
P
A
N
I
S
I
A
I
S
H
S
I
FVKGDQTNFEIGPAGVE
A
S
Q
L
Y
PDVKYTT
V
D
E
Y
L
S
N
F
V
33
HHSearch
64.64
21%
-90
- C1 -
2ZCU
-
QOR2_ECOLI
A:
[1-207]
-----
M
I
A
I
T
G
A
T
G
Q
L
G
H
Y
V
I
E
S
L
M
K
T
V
P
-
A
--
S
Q
I
-
V
A
I
V
R
---------
N
P
A
K
A
Q
----------
A
L
---
A
A
Q
G
--
I
-
T
V
---
R
Q
-
A
D
Y
--
G
D
E
A
A
L
T
S
A
L
Q
--
G
V
E
K
-
L
L
L
I
S
---------------------------------------------------------------------
P
Q
H
R
N
V
I
N
A
A
K
A
A
G
-
V
K
F
I
A
-
Y
T
S
L
L
H
A
D
-
T
----------------------------
S
P
---
L
G
L
A
D
E
H
I
E
T
E
K
M
L
A
D
----
S
G
I
V
Y
T
L
L
R
N
G
W
Y
S
E
N
-----------
Y
L
------
A
S
A
P
A
A
L
E
H
G
------------
V
------------
F
---------------
I
--
G
-----
A
-------
A
G--
D
-------
G
-
K
I
A
S
------
A
T
R
A
D
Y
A
A
A
A
A
R
V
I
S
E
A
--
G
H
E
G
K
V
Y
E
L
----
A
G
D
-
S
A
---
W
T
L
T
Q
L
A
A
-------------------------------------------------------------------------------
49
HHSearch
63.84
22%
-86
- C1 -
1QYC
-
?
A:
[5-229]
----
S
R
I
L
L
I
G
A
T
G
Y
I
G
R
H
V
A
K
A
S
L
D
L
---
G
--
H
P
T
-
F
L
L
V
R
---------
E
S
T
A
S
S
NS
E
K
A
Q
----
L
L
E
S
F
K
A
S
G
--
A
-
N
I
---
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----------------------------------------------------------------
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LAQAGLTAPPRD
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------------
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---------------
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----
L
S
L
N
E
L
V
A
-------------------------------------------------------------------------------
35
HHSearch
63.28
20%
-79
- C1 -
2X4G
-
?
A:
[13-268]
----
V
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------------------------------
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EMTHY
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---
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G
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----
T
G
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----
L
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M
A
D
L
T
R
-------------------------------------------------------------------------------