@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : OR4D1_HUMAN: (2016-01-13 )
MEPQNTTQVSMFVLLGFSQTQELQKFLFLLFLLVYVTTIVGNLLIMVTVTFDCRLHTPMYFLLRNLALIDLCYSTVTSPKMLVDFLHETKTISYQGCMAQIFFFHLLGGGTVFFLSVMAYDRYIAISQPLRYVTIMNTQLCVGLVVAAWVGGFVHSIVQLALILPLPFCGPNILDNFYCDVPQVLRLACTDTSLLEFLMISNSGLLVIIWFLLLLISYTVILVMLRSHSGKARRKAASTCTTHIIVVSMIFIPCIYIYTWPFTPFLMDKAVSISYTVMTPMLNPMIYTLRNQDMKAAMRRLGKCLVICRE
Atome Classification :
(20 SA)
.........10...-----------------.....20........30........40........50........60........70......-..80........90........100.......110.......120.......130.......140.......150.......160.......170.......-.180.......--190---------.........200....------------....210.......220.......230-----------.---------------------.------......240..------.....250..--------.....260-.---------..----.-------.-----.---...270.......280........290.......300.......310-----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MEPQNT
T
Q
V
S
M
F
V
L
-----------------LGF
S
Q
T
Q
E
L
Q
K
F
L
F
L
L
F
L
L
V
Y
V
T
T
I
VGN
L
L
I
M
V
T
V
T
F
D
C
R
LH
T
P
M
Y
F
L
L
R
N
L
A
L
I
D
L
C
Y
S
TVT-
S
P
K
M
L
V
D
F
L
H
ETKTI
S
Y
Q
G
C
M
A
Q
I
F
F
F
H
LLGGG
T
V
F
F
L
S
V
M
AYD
R
Y
I
AISQ
P
L
R
Y
V
T
I
MN
T
Q
L
C
V
G
L
V
V
A
A
W
V
G
G
F
V
H
S
I
V
Q
L
A
L
ILPLPFC
G
-
P
N
I
L
D
N
FY-C
D
V
P
Q
V
L
R
L
AC--T-----------
D
T
S
L
L
E
F
L
M
IS-NS
G
L
------------
L
V
I
I
W
F
L
L
L
L
I
S
Y
T
V
I
L
V
M
L
RSHSG
K
------------
A
---------------------
R
------
R
K
A
ASTC
T
T
H
I
------
I
V
V
S
M
I
F
I
P
C
--------
I
Y
I
YTW---P---------F
T
----
P
-------
F
-----
L
---
M
DKAV
S
I
S
Y
T
V
M
T
P
M-L
N
P
M
I
Y
T
LRNQ
D
M
K
A
A
M
R
R
L
G
K
C
L
V
I
CRE-------------
2
PsiBlast_PDB
95.22
24%
-161
- C1 -
3REY
1
AA2AR_HUMAN
A:
[14-302]
------------------------------------------------
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
Q
P
-------G
C
G
E
G
Q
V
---
A
C
L
F
E
-----------
D
V
V
P
M
N
Y
M
V
Y
F
-
N
F
F
A
------------
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
A
A
A
R
R
Q
L
K
Q
------------
M
---------------------
E
S
QPLPG
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
F
A
L
C
W
L
P
L
H
I
--
I
N
C
F
T
F
-------------
F
C
----
P
DCSHAP
L
W
-----
L
---
M
Y
L
A
I
V
L
A
H
T
--
N
S
V
-
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
-------------------
1
PsiBlast_PDB
95.09
24%
-158
- C1 -
3PWH
1
?
A:
[14-302]
------------------------------------------------
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
Q
P
-------G
C
G
E
G
Q
V
---
A
C
LF
E
-----------
D
V
V
P
M
N
Y
M
V
Y
F
-
N
F
F
A
------------
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
A
A
A
R
R
Q
L
K
Q
------------
M
---------------------
E
S
QPLPG
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
F
A
L
C
W
L
P
L
H
I
--
I
N
C
F
T
F
-------------
F
C
----
P
DCSHAP
L
W
-----
L
---
M
Y
L
A
I
V
L
A
H
T
--
N
S
V
-
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
-------------------
10
PsiBlast_PDB
94.49
22%
-155
- C1 -
2YDV
6
?
A:
[14-302]
------------------------------------------------
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
A
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
A
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
-
Q
P
K
E
G
K
A
H
-
S
Q
G
C
G
E
G
Q
V
A
C
LF
E
-----------
D
V
V
P
M
N
Y
M
V
Y
F
-
N
F
F
A
------------
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
R
R
Q
L
K
Q
------------
M
---------------------
E
SQ--------
S
T
L
Q
K
E
V
H
-----
A
A
K
S
L
A
I
I
V
G
--------
L
F
A
L
C
W
L
--
P
L
H
I
I
N
C
F
T
F
F
C
----
P
DCSHAP
L
W
-----
L
---
M
Y
L
A
I
V
L
S
H
T
--
N
S
V
-
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
H
V
L
R
Q
Q
-------------
4
PsiBlast_PDB
94.07
24%
-159
- C1 -
3UZA
1
AA2AR_HUMAN
A:
[14-302]
------------------------------------------------
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
Q
P
-------G
C
G
E
G
Q
V
---
A
C
L
F
E
-----------
D
V
V
P
M
N
Y
M
V
Y
F
-
N
F
F
A
------------
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
A
A
A
R
R
Q
L
K
Q
------------
M
---------------------
E
S
QPLPG
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
F
A
L
C
W
L
P
L
H
I
--
I
N
C
F
T
F
-------------
F
C
----
P
DCSHAP
L
W
-----
L
---
M
Y
L
A
I
V
L
A
H
T
--
N
S
V
-
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
-------------------
3
PsiBlast_PDB
94.06
24%
-157
- C1 -
3RFM
1
AA2AR_HUMAN
A:
[14-302]
------------------------------------------------
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
Q
P
-------G
C
G
E
G
Q
V
---
A
C
L
F
E
-----------
D
V
V
P
M
N
Y
M
V
Y
F
-
N
F
F
A
------------
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
A
A
A
R
R
Q
L
K
Q
------------
M
---------------------
E
S
QPLPG
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
F
A
L
C
W
L
P
L
H
I
--
I
N
C
F
T
F
-------------
F
C
----
P
DCSHAP
L
W
-----
L
---
M
Y
L
A
I
V
L
A
H
T
--
N
S
V
-
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
-------------------
5
PsiBlast_PDB
93.99
24%
-158
- C1 -
3UZC
1
AA2AR_HUMAN
A:
[14-302]
------------------------------------------------
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
A
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
A
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
A
G
I
I
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
Q
P
-------G
C
G
E
G
Q
V
---
A
C
L
F
E
-----------
D
V
V
P
M
N
Y
M
V
Y
F
-
N
F
F
A
------------
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
A
A
A
R
R
Q
L
K
Q
------------
M
---------------------
E
S
QPLPG
E
R
A
R
S
T
L
Q
K
E
V
H
A
A
K
S
A
A
I
I
A
G
L
F
A
L
C
W
L
P
L
H
I
--
I
N
C
F
T
F
-------------
F
C
----
P
DCSHAP
L
W
-----
L
---
M
Y
L
A
I
V
L
A
H
T
--
N
S
V
-
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
-------------------
9
PsiBlast_PDB
92.80
22%
-156
- C1 -
2YDO
3
?
A:
[14-302]
------------------------------------------------
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
A
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
A
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
-
Q
P
K
E
G
K
A
H
-
S
Q
G
C
G
E
G
Q
V
A
C
LF
E
-----------
D
V
V
P
M
N
Y
M
V
Y
F
-
N
F
F
A
------------
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
R
R
Q
L
K
Q
------------
M
---------------------
E
S----------
T
L
Q
K
E
V
H
-----
A
A
K
S
L
A
I
I
V
G
--------
L
F
A
L
C
W
L
--
P
L
H
I
I
N
C
F
T
F
F
C
----
P
DCSHAP
L
W
-----
L
---
M
Y
L
A
I
V
L
S
H
T
--
N
S
V
-
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
H
V
L
R
Q
Q
-------------
11
PsiBlast_PDB
92.72
22%
-156
- C1 -
4UG2
3
?
A:
[14-302]
------------------------------------------------
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
A
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
A
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
-
Q
P
K
E
G
K
A
H
-
S
Q
G
C
G
E
G
Q
V
A
C
LF
E
-----------
D
V
V
P
M
N
Y
M
V
Y
F
-
N
F
F
A
------------
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
R
R
Q
L
---------------------------------------------
A
R
S
T
L
Q
K
E
V
H
-----
A
A
K
S
L
A
I
I
V
G
--------
L
F
A
L
C
W
L
--
P
L
H
I
I
N
C
F
T
F
F
C
----
P
DCSHAP
L
W
-----
L
---
M
Y
L
A
I
V
L
S
H
T
--
N
S
V
-
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
H
V
L
R
---------------
7
PsiBlast_PDB
92.55
22%
-156
- C1 -
3VGA
1
AA2AR_HUMAN
A:
[14-302]
------------------------------------------------
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
-
Q
--------
S
Q
G
C
G
E
G
Q
V
A
C
L
F
E
-----------
D
V
V
P
M
N
Y
M
V
Y
F
-
N
F
F
A
------------
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
R
R
Q
L
K
Q
------------
M
---------------------
E
S
Q
PLPG
E
R
A
R
S
T
L
Q
K
E
V
H
-----
A
A
K
S
L
A
I
I
V
G
--------
L
F
A
L
C
W
L--
P
L
H
I
I
N
C
F
T
F
F
C
----
P
D
C
S
H
A
P
L
W
-----
L
---
M
Y
L
A
I
V
L
S
H
T
--
N
S
V
-
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
H
V
L
----------------
12
PsiBlast_PDB
92.42
22%
-153
- C1 -
4UHR
1
AA2AR_HUMAN
A:
[14-302]
------------------------------------------------
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
A
A
A
A
D
I
L
V
G
V
L
A
-
I
P
F
A
I
A
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
A
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
-
Q
P
K
E
G
K
A
----
G
C
G
E
G
Q
V
A
C
LF
E
-----------
D
V
V
P
M
N
Y
M
V
Y
F
-
N
F
F
A
------------
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
R
R
Q
L
K
Q
------------
M
---------------------
E
S
QPLPG
E
R
A
R
S
T
L
Q
K
E
V
H
-----
A
A
K
S
L
A
I
I
V
G
--------
L
F
A
L
C
W
L
--
P
L
H
I
I
N
C
F
T
F
F
C
----
P
DCHAP
L
-
W
-----
L
---
M
Y
L
A
I
V
L
S
H
T
--
N
S
V
-
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
H
V
L
R
Q
Q
-------------
6
PsiBlast_PDB
89.76
22%
-160
- C1 -
3VG9
8
?
A:
[14-302]
------------------------------------------------
L
A
I
A
V
L
A
I
L
G
N
V
L
V
C
W
A
V
W
L
N
S
N
L
Q
N
V
T
N
Y
F
V
V
S
L
A
A
A
D
I
A
V
G
V
L
A
-
I
P
F
A
I
T
--
I
S
T
G
F
C
A
A
C
H
G
C
L
F
I
A
C
F
V
L
V
L
T
Q
S
S
I
F
S
L
L
A
I
A
I
D
R
Y
I
A
I
R
I
P
L
R
Y
N
G
L
V
T
G
T
R
A
K
G
I
I
A
I
C
W
V
L
S
F
A
---
I
G
L
T
P
M
L
G
W
N
N
C
G
-
Q
--------
S
Q
G
C
G
E
G
Q
V
A
C
L
F
E
-----------
D
V
V
P
M
N
Y
M
V
Y
F
-
N
F
F
A
------------
C
V
L
V
P
L
L
L
M
L
G
V
Y
L
R
I
F
L
A
A
R
R
Q
L
K
Q
------------
M
---------------------
E
S
Q
PLPG
E
R
A
R
S
T
L
Q
K
E
V
H
-----
A
A
K
S
L
A
I
I
V
G
--------
L
F
A
L
C
W
L
--
P
L
H
I
I
N
C
F
T
F
F
C
----
P
D
C
S
H
A
P
L
W
-----
L
---
M
Y
L
A
I
V
L
S
H
T
--
N
S
V
-
V
N
P
F
I
Y
A
Y
R
I
R
E
F
R
Q
T
F
R
K
I
I
R
S
H
V
L
R
---------------
42
Fugue
87.14
20%
-139
- C1 -
1F88
8
OPSD_BOVIN
A:
[1-348]
---
M
N
G
T
E
G
P
N
F
Y
V
PFSNKTGVVRSPFEAPQ
Y
Y
L
A
E
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
-
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
-
F
G
E
N
H
A
I
M
G
V
A
F
T
W
V
M
A
L
A
C
A
---------------
A
P
P
L
V
G
W
S
-
R
Y
I
P
E
G
M
Q
C
S
C
--
G
I
DYYTPHEETN
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
------------
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
S
A
T
T
Q
K
------------
A
---------------------
E
------
K
E
V
T
R
M
V
I
I
M
V
------
I
A
F
L
I
C
W
L
P
Y
--------
A
G
V
A
F
Y
---
I
---------
F
T
H
QGS
D
-------
F
-----
G
---
P
I
F
M
T
I
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
P
S
T
TVSKTETS
Q
V
A
P
A
36
HHSearch
85.72
15%
-145
- C1 -
2Z73
5
OPSD_TODPA
A:
[33-335]
---------------------------------------
V
Y
Y
S
L
G
I
F
I
G
I
C
G
I
I
G
C
G
G
N
G
I
V
I
Y
L
F
T
K
T
K
S
L
Q
T
P
A
N
M
F
I
I
N
L
A
F
S
D
F
T
F
S
L
V
N
G
F
P
L
M
T
I
S
C
F
L
K
K
W
I
F
G
F
A
A
C
K
V
Y
G
F
I
G
G
I
F
G
F
M
S
I
M
T
M
A
M
I
S
I
D
R
Y
N
V
I
G
R
P
M
A
A
S
K
K
M
S
H
R
R
A
F
I
M
I
I
F
V
W
L
W
S
V
L
W
A
I
G
P
I
F
G
W
G
A
Y
T
L
-----
E
G
V
L
C
N
-
C
S
F
D
Y
I
S
------------------
R
D
S
T
T
R
S
N
I
L
C
-
M
F
I
L
------------
G
F
F
G
P
I
L
I
I
F
F
C
Y
F
N
I
V
M
S
V
S
N
H
E
K
E
------------
M
A
A
M
A
K
RLNAKE
L
R
K
A
Q
A
G
A
N
A
E
------
M
R
L
A
K
I
S
I
V
I
V
------
S
Q
F
L
L
S
W
S
P
Y
--------
A
V
V
A
L
L
---
A
---------
Q
F
----
G
-------
P
LEWVT
P
---
Y
A
A
Q
L
P
V
M
F
A
K
A
S
A
I
-
H
N
P
M
I
Y
S
V
S
H
P
K
F
R
E
A
I
S
Q
T
F
P
W
V
L
T
C
C
Q
-------------
19
PsiBlast_PDB
83.85
22%
-150
- C1 -
1F88
7
OPSD_BOVIN
A:
[44-317]
----------------------------------------------
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
-
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
---------
M
A
L
A
-----
C
A
-
A
P
P
L
V
G
W
S
-
R
Y
I
P
E
G
M
Q
C
S
C
--
G
-----------
I
D
Y
Y
T
P
H
E
E
T
N
-
N
E
S
F
V
I
Y
M
F
V
VHF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
----
S
A
------------
T
---------------------
T
------
Q
K
A
E
K
E
V
T
R
M
V
------
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
QGS
D
---------
F
G
----
P
-------
I
-----
F
---
M
--
T
I
P
A
F
F
A
K
T
S
A
V
-
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
P
S
T
-------------
20
PsiBlast_PDB
83.80
22%
-159
- C1 -
3DQB
4
GNAT1_BOVIN (first)
A:
[44-317]
----------------------------------------------
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
-
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
---------
M
A
L
A
-----
C
A
-
A
P
P
L
V
G
W
S
-
R
Y
I
P
E
G
M
Q
C
S
C
--
G
-----------
I
D
Y
Y
T
P
H
E
E
T
N
-
N
E
S
F
V
I
Y
M
F
V
VHF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
Q
E
S
A
------------
T
---------------------
T
------
Q
K
A
E
K
E
V
T
R
M
V
------
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
QG
S
D
---------
F
G
----
P
-------
I
-----
F
---
M
--
T
I
P
A
F
F
A
K
T
S
A
V
-
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
----------------
18
PsiBlast_PDB
83.80
22%
-147
- C1 -
3C9L
13
OPSD_BOVIN
A:
[44-317]
----------------------------------------------
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
-
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
---------
M
A
L
A
-----
C
A
-
A
P
P
L
V
G
W
S
-
R
Y
I
P
E
G
M
Q
C
S
C
--
G
-----------
I
D
Y
Y
T
P
H
E
E
T
N
-
N
E
S
F
V
I
Y
M
F
V
VHF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
Q
E
S
A
------------
T
---------------------
T
------
Q
K
A
E
K
E
V
T
R
M
V
------
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
QGS
D
---------
F
G
----
P
-------
I
-----
F
---
M
--
T
I
P
A
F
F
A
K
T
S
A
V
-
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
D
D
E
-------------
15
PsiBlast_PDB
83.50
22%
-143
- C1 -
3C9M
1
OPSD_BOVIN
A:
[44-317]
----------------------------------------------
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
-
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
---------
M
A
L
A
-----
C
A
-
A
P
P
L
V
G
W
S
-
R
Y
I
P
E
G
M
Q
C
S
C
--
G
-----------
I
D
Y
Y
T
P
H
E
E
T
N
-
N
E
S
F
V
I
Y
M
F
V
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
Q
E
S
A
------------
T
---------------------
T
------
Q
K
A
E
K
E
V
T
R
M
V
------
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
---
Q
GSC------
F
G
----
P
-------
I
-----
F
---
M
--
T
I
P
A
F
F
A
K
T
S
A
V
-
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
P
---------------
17
PsiBlast_PDB
82.54
22%
-162
- C1 -
3CAP
4
OPSD_BOVIN
A:
[44-317]
----------------------------------------------
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
-
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
G
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
---------
M
A
L
A
-----
C
A
-
A
P
P
L
V
G
W
S
-
R
Y
I
P
E
G
M
Q
C
S
C
--
G
-----------
I
D
Y
Y
T
P
H
E
E
T
N
-
N
E
S
F
V
I
Y
M
F
V
VHF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
Q
E
S
A
------------
T
---------------------
T
------
Q
K
A
E
K
E
V
T
R
M
V
------
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
QGS
D
---------
F
G
----
P
-------
I
-----
F
---
M
--
T
I
P
A
F
F
A
K
T
S
A
V
-
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
----------------
33
HHSearch
81.69
17%
-143
* C1 *
2KS9
1
NK1R_HUMAN
A:
[33-324]
-----------------------------------------
V
L
W
A
A
A
Y
T
V
I
V
V
T
S
V
V
G
N
V
V
V
M
W
I
I
L
A
H
K
R
M
R
T
V
T
N
Y
F
L
V
N
L
A
F
A
E
A
S
M
A
A
F
N
-
T
V
V
N
F
T
Y
A
V
H
N
E
W
Y
Y
G
L
F
Y
C
K
F
H
N
F
F
P
I
A
A
V
F
A
S
I
Y
S
M
T
A
V
A
F
D
R
Y
M
A
I
I
H
P
L
Q
P
R
L
--
S
A
T
A
T
K
V
V
I
C
V
I
W
V
L
A
L
L
L
A
F
P
Q
G
Y
Y
S
T
T
E
T
------
M
P
S
R
V
V
-
C
M
I
E
W
P
E
H
P
----------------
N
K
I
Y
E
K
V
Y
H
I
C
-
V
T
V
L
------------
I
Y
F
L
P
L
L
V
I
G
Y
A
Y
T
V
V
G
I
T
L
W
A
S
E
I
P
GDSSDRYH
E
Q
V
S
A
---------------------
K
------
R
K
V
V
K
M
M
I
V
V
V
------
C
T
F
A
I
C
W
L
P
F
--------
H
I
F
F
L
L
---
P
---------
Y
I
----
N
PD-----
L
YLK--
K
FI
Q
Q
V
Y
L
A
I
M
W
L
A
M
S
S
T
M
-
Y
N
P
I
I
Y
C
C
L
N
D
R
F
R
L
G
F
K
H
A
F
R
C
C
P
F
I
S
A
-------------
13
PsiBlast_PDB
81.12
22%
-137
- C1 -
4BEZ
3
OPSD_BOVIN
A:
[47-318]
----------------------------------------------
M
F
L
L
I
M
L
G
F
P
I
N
F
L
T
L
Y
V
T
V
Q
H
K
-
K
L
R
T
P
L
N
Y
I
L
L
N
L
A
V
A
D
L
F
M
V
F
G
D
-
F
T
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
-
V
A
F
T
W
V
---------
M
A
L
A
-----
C
A
-
A
P
P
L
V
G
W
S
-
R
Y
I
P
E
G
M
Q
C
S
C
--
G
-----------
I
D
Y
Y
T
P
H
E
E
T
N
-
N
E
S
F
V
I
Y
M
F
V
V
HF
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
Q
E
S
A
------------
T
---------------------
T
------
Q
K
A
E
K
E
V
T
R
M
V
------
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
Y
I
F
T
H
---
Q
G
S
C
------
F
G
----
P
-------
I
-----
F
---
M
--
T
I
P
A
F
F
A
K
T
S
A
V
-
Y
N
P
V
I
Y
I
M
M
N
K
Q
F
R
N
C
M
V
T
T
L
C
C
G
K
N
----------------