@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SA0118: (2016-03-12 )
MMQQLSLKHRLNNGDSVYGIFNSIPDPLMIEVIAASGYDFVVIDTEHVAINDETLAHLIRAAEAAHIIPIVRVTAVIDRDIIKVLDMGARGIIVPHVKDRETVEHIVKLSRYYPQGLRSLNGGRMARFGRTPLLDAMEMANEHIMVIAMIEDVEGVMAIDDIAQVEGLDMIVEGAADLSQSLGIPWQTRDDQVTSHVQHIFEVVNAHGKHFCALPREDEDIAKWQAQGVQTFILGDDRGKIYRHLSASLATSKQKGDDG
Atome Classification :
(20 SA)
-------------------------.........10..-----..-....20...-......30........40........50........60...---.---...--.70........80........90........100.......110----.......120-.--.-......130---...-----.....140.......150.......160.......170.......180....-----...-----190.......200.----......210....-.....-220.....----..230.......240.......250......--.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------------MMQQ
L
S
L
K
HRLNN-----GD-
S
V
Y
G
I
-
F
N
S-IPDP
L
M
I
E
V
I
AASG
Y
D
F
V
V
I
DT
E
H
V
A
I
N
D
E
T
L
A
H
L
I
R
A
AEA---
A
---
H
I
I
--
P
I
V
R
V
T
A
V
I
D
R
D
I
I
K
V
L
DMGAR
G
I
I
VPHVK
D
R
E
T
V
E
H
I
V
K
L
S
R
Y
----
Y
P
Q
G
L
R
SLN--G--G-RMARFGRT----
P
L
L
-----
D
A
M
E
MANE
H
I
M
V
I
A
M
IEDVE
G
V
M
A
I
D
D
I
A
Q
VE
G
L
D
M
I
V
E
G
A
A
D
L
S
Q
SLGIPW-----QTR-----
D
D
Q
V
T
S
H
V
Q
H
I
F
E
V
----
V
NAHG
K
H
--
F
CAL-PRE
D
E
-
D
I
A
K
W
Q
AQ----G
V
Q
T
F
I
LGDDR
G
K
I
Y
R
H
L
S
A
S
L
ATSKQKGDD--G
1
PsiBlast_PDB
94.79
99%
-138
- C7 -
4TV5
2
?
A:
[4-258]
----------------------------
Q
L
S
L
K
H
R
L
N
N
-----
G
D
-
S
V
Y
G
I
-
F
N
S
-
I
P
D
P
L
M
I
E
V
I
A
A
S
G
Y
D
F
V
V
I
D
T
E
H
V
A
I
N
D
E
T
L
A
H
L
I
R
A
A
E
A
---
A
---
H
I
I
--
P
I
V
R
V
T
A
V
I
D
R
D
I
I
K
V
L
D
M
G
A
R
G
I
I
V
P
H
V
K
D
R
E
T
V
E
H
I
V
K
L
S
R
Y
----
Y
P
Q
G
L
R
S
L
N
-------------------
P
L
L
-----
D
A
M
E
M
A
N
E
H
I
M
V
I
A
M
I
E
D
V
E
G
V
M
A
I
D
D
I
A
Q
V
E
G
L
D
M
I
V
E
G
A
A
D
L
S
Q
S
L
G
I
P
W
-----
Q
T
R
-----
D
D
Q
V
T
S
H
V
Q
H
I
F
E
V
----
V
N
A
H
G
K
H
--
F
C
A
L
-
P
R
E
D
E
-
D
I
A
K
W
Q
A
Q
----
G
V
Q
T
F
I
L
G
D
D
R
G
K
I
Y
R
H
L
S
A
S
L
A
T
S
K
Q
K
G
D
E
---
2
PsiBlast_PDB
93.72
99%
-159
- C7 -
4TV6
1
?
A:
[6-257]
------------------------------
S
L
K
H
R
L
N
N
-----
G
D
-
S
V
Y
G
I
-
F
N
S
-
I
P
D
P
L
M
I
E
V
I
A
A
S
G
Y
D
F
V
V
I
D
T
E
H
V
A
I
N
D
E
T
L
A
H
L
I
R
A
A
E
A
---
A
---
H
I
I
--
P
I
V
R
V
T
-----
D
I
I
K
V
L
D
M
G
A
R
G
I
I
V
P
H
V
K
D
R
E
T
V
E
H
I
V
K
L
S
R
Y
----
Y
P
Q
G
L
R
S
L
------------------------------------
H
I
M
V
I
A
M
I
Q
D
V
E
G
V
M
A
I
D
D
I
A
Q
V
E
G
L
D
M
I
V
E
G
A
A
D
L
S
Q
S
L
G
I
P
W
-----
Q
T
R
-----
D
D
Q
V
T
S
H
V
Q
H
I
F
E
V
----
V
N
A
H
G
K
H
--
F
C
A
L
-
P
R
E
D
E
-
D
I
A
K
W
Q
A
Q
----
G
V
Q
T
F
I
L
G
D
D
R
G
K
I
Y
R
H
L
S
A
S
L
A
T
S
K
Q
K
G
D
----
88
HHSearch
77.71
27%
-121
- C7 -
3QZ6
1
?
A:
[3-258]
----------------------------
A
M
F
L
K
K
K
L
S
A
-----
G
K
-
S
V
V
G
T
-
M
L
N
L
V
Y
N
P
D
I
V
R
I
Y
A
E
A
G
L
D
Y
F
I
V
D
C
E
H
A
A
Y
T
F
R
E
I
N
H
L
V
S
V
A
K
N
---
A
---
G
V
S
--
V
L
V
R
I
P
Q
V
D
R
A
H
V
Q
R
L
L
D
I
G
A
E
G
F
M
I
P
G
V
Q
S
A
E
T
M
R
E
T
V
R
L
A
K
Y
----
P
P
L
G
E
R
G
V
G
--
G
--
S
-
I
V
T
D
F
K
P
V
----
N
W
A
-----
E
W
V
Q
E
R
N
D
E
I
F
I
M
A
Q
I
E
H
V
K
A
V
E
D
I
D
S
I
L
A
V
Q
G
V
D
A
V
I
F
G
P
R
D
L
S
N
D
L
G
I
I
G
-----
Q
T
E
-----
H
P
K
V
Y
E
C
Y
E
K
V
Y
R
A
----
A
D
R
Q
G
V
V
--
K
G
F
F
-
T
A
A
D
A
A
K
M
G
W
A
V
E
R
----
G
A
Q
M
L
L
W
S
G
D
V
A
A
L
Q
T
Y
T
A
K
G
V
K
T
I
K
E
L
P
G
----
3
PsiBlast_PDB
73.97
28%
-125
- C7 -
3QZ6
1
?
A:
[6-255]
-------------------------------
L
K
K
K
L
S
A
-----
G
K
-
S
V
V
G
T
M
L
N
L
-
V
Y
N
P
D
I
V
R
I
Y
A
E
A
G
L
D
Y
F
I
V
D
C
E
H
A
A
Y
T
F
R
E
I
N
H
L
V
S
V
A
K
N
---
A
---
G
V
S
--
V
L
V
R
I
P
Q
V
D
R
A
H
V
Q
R
L
L
D
I
G
A
E
G
F
M
I
P
G
V
Q
S
A
E
T
M
R
E
T
V
R
L
A
K
Y
----
P
P
L
G
E
R
G
V
G
--
G
--
S
-
I
V
T
D
F
K
P
V
----
N
W
A
-----
E
W
V
Q
E
R
N
D
E
I
F
I
M
A
Q
I
E
H
V
K
A
V
E
D
I
D
S
I
L
A
V
Q
G
V
D
A
V
I
F
G
P
R
D
L
S
N
D
L
G
I
I
G
-----
Q
T
E
-----
H
P
K
V
Y
E
C
Y
E
K
V
Y
R
A
----
A
D
R
Q
G
V
V
--
K
G
F
F
-
T
A
A
D
A
-
A
K
M
G
W
A
V
E
R
---
G
A
Q
M
L
L
W
S
G
D
V
A
A
L
Q
T
Y
T
A
K
G
V
K
T
I
K
E
-------
89
HHSearch
69.89
29%
-113
- C7 -
2VWS
3
RHMA_ECOLI
A:
[4-256]
--------------------------
L
L
S
N
P
F
K
E
R
L
R
K
-----
G
E
-
V
Q
I
G
L
-
W
L
S
-
S
T
T
A
Y
M
A
E
I
A
A
T
S
G
Y
D
W
L
L
I
D
G
E
H
A
P
N
T
I
Q
D
L
Y
H
Q
L
Q
A
V
A
P
---
Y
---
A
S
Q
--
P
V
I
R
P
V
E
G
S
K
P
L
I
K
Q
V
L
D
I
G
A
Q
T
L
L
I
P
M
V
D
T
A
E
Q
A
R
Q
V
V
S
A
T
R
Y
----
P
P
Y
G
E
R
G
V
G
A-
S
V-
A
-
R
A
A
R
W
G
R
------
I
E
-----
N
Y
M
A
Q
V
N
D
S
L
C
L
L
V
Q
V
E
S
K
T
A
L
D
N
L
D
E
I
L
D
V
E
G
I
D
G
V
F
I
G
P
A
D
L
S
A
S
L
G
Y
P
D
-----
N
A
G
-----
H
P
E
V
Q
R
I
I
E
T
S
I
R
R
----
I
R
A
A
G
K
A
--
A
G
F
L
-
A
V
-
A
P
D
M
A
Q
Q
C
L
A
W
----
G
A
N
F
V
A
V
G
V
D
T
M
L
Y
S
D
A
L
D
Q
R
L
A
M
F
K
S
-------
87
HHSearch
69.80
26%
-111
* C7 *
2V5J
5
HPCH_ECOLX
A:
[26-278]
---------------------------
M
E
N
S
F
K
A
A
L
K
A
-----
G
R
-
P
Q
I
G
L
-
W
L
G
-
L
S
S
S
Y
S
A
E
L
L
A
G
A
G
F
D
W
L
L
I
D
G
E
H
A
P
N
N
V
Q
T
V
L
T
Q
L
Q
A
I
A
P
---
Y
---
P
S
Q
--
P
V
V
R
P
S
W
N
D
P
V
Q
I
K
Q
L
L
D
V
G
T
Q
T
L
L
V
P
M
V
Q
N
A
D
E
A
R
E
A
V
R
A
T
R
Y
----
P
P
A
G
I
R
G
V
G
SA
L
--
A
-
R
A
S
R
W
N
R
------
I
P
-----
D
Y
L
Q
K
A
N
D
Q
M
C
V
L
V
Q
I
E
T
R
E
A
M
K
N
L
P
Q
I
L
D
V
E
G
V
D
G
V
F
I
G
P
A
D
L
S
A
D
M
G
Y
A
G
-----
N
P
Q
-----
H
P
E
V
Q
A
A
I
E
Q
A
I
V
Q
----
I
R
E
S
G
K
A
--
P
G
I
L
-
I
A
-
N
E
Q
L
A
K
R
Y
L
E
L
----
G
A
L
F
V
A
V
G
V
D
T
T
L
L
A
R
A
A
E
A
L
A
A
R
F
G
A
Q
------
90
HHSearch
69.63
29%
-111
- C7 -
1DXE
3
GARL_ECOLI
A:
[6-255]
---------------------------
F
P
N
K
F
K
A
A
L
A
A
-----
K
Q
-
V
Q
I
G
C
-
W
S
A
-
L
S
N
P
I
S
T
E
V
L
G
L
A
G
F
D
W
L
V
L
D
G
E
H
A
P
N
D
I
S
T
F
I
P
Q
L
M
A
L
K
G
---
S
---
A
S
A
--
P
V
V
R
V
P
T
N
E
P
V
I
I
K
R
L
L
D
I
G
F
Y
N
F
L
I
P
F
V
E
T
K
E
E
A
E
L
A
V
A
S
T
R
Y
----
P
P
E
G
I
R
G
V
S
V-
S
--
H
-
R
A
N
M
F
G
T
------
V
A
-----
D
Y
F
A
Q
S
N
K
N
I
T
I
L
V
Q
I
E
S
Q
Q
G
V
D
N
V
D
A
I
A
A
T
E
G
V
D
G
I
F
V
G
P
S
D
L
A
A
A
L
G
H
L
G
-----
N
A
S
-----
H
P
D
V
Q
K
A
I
Q
H
I
F
N
R
----
A
S
A
H
G
K
P
--
S
G
I
L
-
A
P
-
V
E
A
D
A
R
R
Y
L
E
W
----
G
A
T
F
V
A
V
G
S
D
L
G
V
F
R
S
A
T
Q
K
L
A
D
T
F
K
--------
109
Fugue
69.02
27%
-109
- C7 -
1DXE
3
GARL_ECOLI
A:
[4-256]
-------------------------
D
V
F
P
N
K
F
K
A
A
L
A
A
-----
K
Q
-
V
Q
I
G
C
-
W
S
A
-
L
S
N
P
I
S
T
E
V
L
G
L
A
G
F
D
W
L
V
L
D
G
E
H
A
P
N
D
I
S
T
F
I
P
Q
L
M
A
L
K
G
---
S
---
A
S
A
--
P
V
V
R
V
P
T
N
E
P
V
I
I
K
R
L
L
D
I
G
F
Y
N
F
L
I
P
F
V
E
T
K
E
E
A
E
L
A
V
A
S
T
R
Y
----
P
P
E
G
I
R
G
V
S
--
V
--
S
-
H
R
A
N
M
F
G
T
----
V
A
------
D
Y
F
A
Q
S
N
K
N
I
T
I
L
V
Q
I
E
S
Q
Q
G
V
D
N
V
D
A
I
A
A
T
E
G
V
D
G
I
F
V
G
P
S
D
L
A
A
A
L
G
H
L
G
-----
N
A
S
-----
H
P
D
V
Q
K
A
I
Q
H
I
F
N
R
----
A
S
A
H
G
K
P
--
S
G
I
L
-
A
P
V
E
A
-
D
A
R
R
Y
L
E
W
----
G
A
T
F
V
A
V
G
S
D
L
G
V
F
R
S
A
T
Q
K
L
A
D
T
F
K
K
-------
110
Fugue
68.66
25%
-114
- C7 -
1IZC
2
?
A:
[2-300]
AKSYSEQPELHAKAPYRSAMLTYPG
N
L
R
Q
A
L
K
D
A
M
A
D
P
-----
S
K
-
T
L
M
G
V
-
A
H
G
-
I
P
S
T
F
V
T
K
V
L
A
A
T
K
P
D
F
V
W
I
D
V
E
H
G
M
F
N
R
L
E
L
H
D
A
I
H
A
A
Q
H
---
H
S
E
G
R
S
L
--
V
I
V
R
V
P
K
H
D
E
V
S
L
S
T
A
L
D
A
G
A
A
G
I
V
I
P
H
V
E
T
V
E
E
V
R
E
F
V
K
E
M
Y
Y
----
G
P
I
G
R
R
S
F
S
--
P
--
W
-
T
F
S
P
G
I
A
D
----
A
S
L
FPNDP
Y
N
V
A
T
S
N
N
H
V
C
I
I
P
Q
I
E
S
V
K
G
V
E
N
V
D
A
I
A
A
M
P
E
I
H
G
L
M
F
G
P
G
D
Y
M
I
D
A
G
L
D
L
-----
N
G
A
LSGVP
H
P
T
F
V
E
A
M
T
K
F
S
T
A
----
A
Q
R
N
G
V
P
--
I
F
G
G
-
A
L
S
V
D
-
M
V
P
S
L
I
E
Q
----
G
Y
R
A
I
A
V
Q
F
D
V
W
G
L
S
R
L
V
H
G
S
L
A
Q
A
R
A
S
A
K
Q
FA
G
5
PsiBlast_PDB
67.29
29%
-118
- C7 -
1DXE
3
GARL_ECOLI
A:
[22-256]
-------------------------------------------------
G
C
-
W
S
A
-
L
S
N
P
I
S
T
E
V
L
G
L
A
G
F
D
W
L
V
L
D
G
E
H
A
P
N
D
I
S
T
F
I
P
Q
L
M
A
L
K
G
---
S
---
A
S
A
--
P
V
V
R
V
P
T
N
E
P
V
I
I
K
R
L
L
D
I
G
F
Y
N
F
L
I
P
F
V
E
T
K
E
E
A
E
L
A
V
A
S
T
R
Y
----
P
P
E
G
I
R
G
V
S
V-
S
--
H
-
R
A
N
M
F
G
T
------
V
A
-----
D
Y
F
A
Q
S
N
K
N
I
T
I
L
V
Q
I
E
S
Q
Q
G
V
D
N
V
D
A
I
A
A
T
E
G
V
D
G
I
F
V
G
P
S
D
L
A
A
A
L
G
H
L
G
-----
N
A
S
-----
H
P
D
V
Q
K
A
I
Q
H
I
F
N
R
----
A
S
A
H
G
K
P
--
S
G
I
L
-
A
P
V
E
A
-
D
A
R
R
Y
L
E
W
----
G
A
T
F
V
A
V
G
S
D
L
G
-
V
F
R
S
A
T
Q
K
L
A
D
T
F
K
K
------
4
PsiBlast_PDB
67.15
29%
-118
- C7 -
1DXF
2
GARL_ECOLI
A:
[22-256]
-------------------------------------------------
G
C
-
W
S
A
-
L
S
N
P
I
S
T
E
V
L
G
L
A
G
F
D
W
L
V
L
D
G
E
H
A
P
N
D
I
S
T
F
I
P
Q
L
M
A
L
K
G
---
S
---
A
S
A
--
P
V
V
R
V
P
T
N
E
P
V
I
I
K
R
L
L
D
I
G
F
Y
N
F
L
I
P
F
V
E
T
K
E
E
A
E
L
A
V
A
S
T
R
Y
----
P
P
E
G
I
R
G
V
S
V-
S
--
H
-
R
A
N
M
F
G
T
------
V
A
-----
D
Y
F
A
Q
S
N
K
N
I
T
I
L
V
Q
I
E
S
Q
Q
G
V
D
N
V
D
A
I
A
A
T
E
G
V
D
G
I
F
V
G
P
S
D
L
A
A
A
L
G
H
L
G
-----
N
A
S
-----
H
P
D
V
Q
K
A
I
Q
H
I
F
N
R
----
A
S
A
H
G
K
P
--
S
G
I
L
-
A
P
V
E
A
-
D
A
R
R
Y
L
E
W
----
G
A
T
F
V
A
V
G
S
D
L
G
-
V
F
R
S
A
T
Q
K
L
A
D
T
F
K
K
------
91
HHSearch
66.90
25%
-108
- C7 -
1IZC
2
?
A:
[23-294]
--------------------------
T
Y
P
G
N
L
R
Q
A
L
K
D
A
M
A
DP
S
K
-
T
L
M
G
V
-
A
H
G
-
I
P
S
T
F
V
T
K
V
L
A
A
T
K
P
D
F
V
W
I
D
V
E
H
G
M
F
N
R
L
E
L
H
D
A
I
H
A
A
Q
H
H
S
E
G
---
R
S
L
--
V
I
V
R
V
P
K
H
D
E
V
S
L
S
T
A
L
D
A
G
A
A
G
I
V
I
P
H
V
E
T
V
E
E
V
R
E
F
V
K
E
M
Y
Y
----
G
P
I
G
R
R
S
F
S
P-
W
--
T
-
F
S
P
G
I
A
D
A
SLFP
N
D
P
-----
Y
N
V
A
T
S
N
N
H
V
C
I
I
P
Q
I
E
S
V
K
G
V
E
N
V
D
A
I
A
A
M
P
E
I
H
G
L
M
F
G
P
G
D
Y
M
I
D
A
G
L
D
L
NGALS
G
V
P
-----
H
P
T
F
V
E
A
M
T
K
F
S
T
A
----
A
Q
R
N
G
V
P
--
I
F
G
G
-
A
L
-
S
V
D
M
V
P
S
L
I
E
Q
----
G
Y
R
A
I
A
V
Q
F
D
V
W
G
L
S
R
L
V
H
G
S
L
A
Q
A
R
A
S
------
7
PsiBlast_PDB
65.38
31%
-119
- C7 -
2VWS
3
RHMA_ECOLI
A:
[9-245]
-------------------------------
F
K
E
R
L
R
K
-----
G
E
-
V
Q
I
G
L
-
W
L
S
-
S
T
T
A
Y
M
A
E
I
A
A
T
S
G
Y
D
W
L
L
I
D
G
E
H
A
P
N
T
I
Q
D
L
Y
H
Q
L
Q
A
V
A
P
---
Y
---
A
S
Q
--
P
V
I
R
P
V
E
G
S
K
P
L
I
K
Q
V
L
D
I
G
A
Q
T
L
L
I
P
M
V
D
T
A
E
Q
A
R
Q
V
V
S
A
T
R
Y
----
P
P
Y
G
E
R
G
V
G
--
A
SV
A
-
R
A
A
R
W
G
R
------
I
E
-----
N
Y
M
A
Q
V
N
D
S
L
C
L
L
V
Q
V
E
S
K
T
A
L
D
N
L
D
E
I
L
D
V
E
G
I
D
G
V
F
I
G
P
A
D
L
S
A
S
L
G
Y
P
--------------
D
N
A
G
H
P
E
V
Q
R
I
I
E
T
S
I
R
R
I
R
A
A
G
K
A
A
G
F
L
A
V
A
P
D
M
A
Q
-
Q
C
L
A
W
G
A
N
FVAV
G
V
D
T
M
L
Y
S
D
-------------------------
8
PsiBlast_PDB
65.29
31%
-118
- C7 -
2VWT
3
RHMA_ECOLI
A:
[9-245]
-------------------------------
F
K
E
R
L
R
K
-----
G
E
-
V
Q
I
G
L
-
W
L
S
-
S
T
T
A
Y
M
A
E
I
A
A
T
S
G
Y
D
W
L
L
I
D
G
E
H
A
P
N
T
I
Q
D
L
Y
H
Q
L
Q
A
V
A
P
---
Y
---
A
S
Q
--
P
V
I
R
P
V
E
G
S
K
P
L
I
K
Q
V
L
D
I
G
A
Q
T
L
L
I
P
M
V
D
T
A
E
Q
A
R
Q
V
V
S
A
T
R
Y
----
P
P
Y
G
E
R
G
V
G
--
A
SV
A
-
R
A
A
R
W
G
R
------
I
E
-----
N
Y
M
A
Q
V
N
D
S
L
C
L
L
V
Q
V
E
S
K
T
A
L
D
N
L
D
E
I
L
D
V
E
G
I
D
G
V
F
I
G
P
A
D
L
S
A
S
L
G
Y
P
--------------
D
N
A
G
H
P
E
V
Q
R
I
I
E
T
S
I
R
R
I
R
A
A
G
K
A
A
G
F
L
A
V
A
P
D
M
A
Q
-
Q
C
L
A
W
G
A
N
FVAV
G
V
D
T
M
L
Y
S
D
-------------------------
25
PsiBlast_CBE
65.23
31%
-116
- C7 -
2VWT
4
RHMA_ECOLI
C:
[9-245]
-------------------------------
F
K
E
R
L
R
K
-----
G
E
-
V
Q
I
G
L
-
W
L
S
-
S
T
T
A
Y
M
A
E
I
A
A
T
S
G
Y
D
W
L
L
I
D
G
E
H
A
P
N
T
I
Q
D
L
Y
H
Q
L
Q
A
V
A
P
---
Y
---
A
S
Q
--
P
V
I
R
P
V
E
G
S
K
P
L
I
K
Q
V
L
D
I
G
A
Q
T
L
L
I
P
M
V
D
T
A
E
Q
A
R
Q
V
V
S
A
T
R
Y
----
P
P
Y
G
E
R
G
V
G
--
A
SV
A
-
R
A
A
R
W
G
R
------
I
E
-----
N
Y
M
A
Q
V
N
D
S
L
C
L
L
V
Q
V
E
S
K
T
A
L
D
N
L
D
E
I
L
D
V
E
G
I
D
G
V
F
I
G
P
A
D
L
S
A
S
L
G
Y
P
--------------
D
N
A
G
H
P
E
V
Q
R
I
I
E
T
SIRR
I
R
A
A
G
K
A
AG
F
L
A
V
A
P
D
M
A
Q
-
Q
C
L
A
W
G
A
N
FVAV
G
V
D
T
M
L
Y
S
D
-------------------------
26
PsiBlast_CBE
65.16
31%
-114
- C7 -
2VWT
3
RHMA_ECOLI
B:
[9-245]
-------------------------------
F
K
E
R
L
R
K
-----
G
E
-
V
Q
I
G
L
-
W
L
S
-
S
T
T
A
Y
M
A
E
I
A
A
T
S
G
Y
D
W
L
L
I
D
G
E
H
A
P
N
T
I
Q
D
L
Y
H
Q
L
Q
A
V
A
P
---
Y
---
A
S
Q
--
P
V
I
R
P
V
E
G
S
K
P
L
I
K
Q
V
L
D
I
G
A
Q
T
L
L
I
P
M
V
D
T
A
E
Q
A
R
Q
V
V
S
A
T
R
Y
----
P
P
Y
G
E
R
G
V
G
--
A
SV
A
-
R
A
A
R
W
G
R
------
I
E
-----
N
Y
M
A
Q
V
N
D
S
L
C
L
L
V
Q
V
E
S
K
T
A
L
D
N
L
D
E
I
L
D
V
E
G
I
D
G
V
F
I
G
P
A
D
L
S
A
S
L
G
Y
P
--------------
D
N
A
G
H
P
E
V
Q
R
I
I
E
T
SIRR
I
R
A
A
G
K
A
AG
F
L
A
V
A
P
D
M
A
Q
-
Q
C
L
A
W
G
A
N
FVAV
G
V
D
T
M
L
Y
S
D
-------------------------
28
PsiBlast_CBE
65.00
31%
-115
- C7 -
2VWS
1
RHMA_ECOLI
B:
[9-245]
-------------------------------
F
K
E
R
L
R
K
-----
G
E
-
V
Q
I
G
L
-
W
L
S
-
S
T
T
A
Y
M
A
E
I
A
A
T
S
G
Y
D
W
L
L
I
D
G
E
H
A
P
N
T
I
Q
D
L
Y
H
Q
L
Q
A
V
A
P
---
Y
---
A
S
Q
--
P
V
I
R
P
V
E
G
S
K
P
L
I
K
Q
V
L
D
I
G
A
Q
T
L
L
I
P
M
V
D
T
A
E
Q
A
R
Q
V
V
S
A
T
R
Y
----
P
P
Y
G
E
R
G
V
G
--
A
SV
A
-
R
A
A
R
W
G
R
------
I
E
-----
N
Y
M
A
Q
V
N
D
S
L
C
L
L
V
Q
V
E
S
K
T
A
L
D
N
L
D
E
I
L
D
V
E
G
I
D
G
V
F
I
G
P
A
D
L
S
A
S
L
G
Y
P
--------------
D
N
A
G
H
P
E
V
Q
R
I
I
E
T
SIRR
I
R
A
A
G
K
A
AG
F
L
A
V
A
P
D
M
A
Q
-
Q
C
L
A
W
G
A
N
FVAV
G
V
D
T
M
L
Y
S
D
-------------------------
27
PsiBlast_CBE
65.00
31%
-118
- C7 -
2VWS
3
RHMA_ECOLI
C:
[9-245]
-------------------------------
F
K
E
R
L
R
K
-----
G
E
-
V
Q
I
G
L
-
W
L
S
-
S
T
T
A
Y
M
A
E
I
A
A
T
S
G
Y
D
W
L
L
I
D
G
E
H
A
P
N
T
I
Q
D
L
Y
H
Q
L
Q
A
V
A
P
---
Y
---
A
S
Q
--
P
V
I
R
P
V
E
G
S
K
P
L
I
K
Q
V
L
D
I
G
A
Q
T
L
L
I
P
M
V
D
T
A
E
Q
A
R
Q
V
V
S
A
T
R
Y
----
P
P
Y
G
E
R
G
V
G
--
A
SV
A
-
R
A
A
R
W
G
R
------
I
E
-----
N
Y
M
A
Q
V
N
D
S
L
C
L
L
V
Q
V
E
S
K
T
A
L
D
N
L
D
E
I
L
D
V
E
G
I
D
G
V
F
I
G
P
A
D
L
S
A
S
L
G
Y
P
--------------
D
N
A
G
H
P
E
V
Q
R
I
I
E
T
SIRR
I
R
A
A
G
K
A
AG
F
L
A
V
A
P
D
M
A
Q
-
Q
C
L
A
W
G
A
N
FVAV
G
V
D
T
M
L
Y
S
D
-------------------------
6
PsiBlast_PDB
62.04
36%
-124
- C7 -
4MF4
1
?
A:
[15-198]
------------------------------
S
L
K
Q
R
L
R
D
-----
G
D
E
P
L
Y
G
L
-
W
L
S
-
L
G
S
D
S
A
A
E
A
L
A
H
A
G
Y
D
W
L
C
I
D
M
E
H
A
P
N
D
S
R
D
V
A
S
Q
L
R
A
I
A
A
---
A
---
H
L
P
S
E
P
V
V
R
V
P
A
R
E
P
W
L
V
K
R
A
L
D
A
G
A
R
T
L
M
F
P
C
I
E
T
P
D
D
A
A
H
A
V
R
L
T
R
F
PSPE
S
P
D
G
L
R
G
V
A
--
G
--
M
V
R
A
A
A
F
G
M
R
------
R
-----
D
Y
L
Q
T
A
N
A
Q
V
A
V
I
V
Q
V
E
S
A
R
G
V
D
E
V
E
R
I
A
A
T
P
G
V
D
C
L
F
V
G
P
A
D
L
A
A
S
L
G
----------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
61.23
36%
-124
- C7 -
4MF4
2
?
F:
[15-198]
------------------------------
S
L
K
Q
R
L
R
D
-----
G
D
E
P
L
Y
G
L
-
W
L
S
-
L
G
S
D
S
A
A
E
A
L
A
H
A
G
Y
D
W
L
C
I
D
M
E
H
A
P
N
D
S
R
D
V
A
S
Q
L
R
A
I
A
A
---
A
---
H
L
P
SE
P
V
V
R
V
P
A
R
E
P
W
L
V
K
R
A
L
D
A
G
A
R
T
L
M
F
P
C
I
E
T
P
D
D
A
A
H
A
V
R
L
T
R
F
PSPE
S
P
D
G
L
R
G
V
A
--
G
--
M
V
R
A
A
A
F
G
M
R
------
R
-----
D
Y
L
Q
T
A
N
A
Q
V
A
V
I
V
Q
V
E
S
A
R
G
V
D
E
V
E
R
I
A
A
T
P
G
V
D
C
L
F
V
G
P
A
D
L
A
A
S
L
G
----------------------------------------------------------------------------------------------------