@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1278: (2015-12-22 )
MLKKITHQIKALSELVALEHTIFSSMFLLMAMVISSYQKNQTLFFGLETLILCFLALLGARNFAMGFNRLVDRDIDKDNPRTKNRPSVDGRISVKGMVIFSVSNALLFVGVSYFINPLAFKLSLPFLIILGGYSYFKRFSSLAHFVVGLALGLAPIAGSVAVLGDIPLWNVFLALGVMLWVAGFDLLYSLQDMEFDKERGLFSIPSQLGEKWCLNLSRLSHLVALICWLCFVKCYHGGLFAYLGLGVSALILLYEQILVARDYKNIPKAFFVSNGYLGVVFFIFIVLDVGFKHA
Atome Classification :
(20 SA)
-----------------------------------.........10.-----------.......20........30........40........50........60.......----.70.------.....--..80...-----.--....90...---..--...100---....--.--------------..110---.....-----....120.......130.----...---....140..--------...---..150...------------------------....160...-----------...--------.170.......180...---....190.......200-.........210.......220.....---..230.......240.......250.......260...-.....270.......----280...--------....290..---------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------
M
L
K
K
I
T
H
Q
I
K
A
L
-----------
S
E
L
V
A
L
E
H
T
I
F
S
S
M
F
L
L
M
A
M
V
I
S
S
YQKNQ
T
L
F
F
G
L
E
T
L
I
L
C
F
L
A
L
LGA
R
N
F
A
M
G
F
N
----
R
L
V
D------RDIDK--DNPRTKN-----R--PSVD
G
R
I
S
V
---
K
G
--
M
V
I
F
SV---SN
A
L
--
L
--------------
F
V
G
-----
V
S
Y
F
I
-----
N
P
L
A
F
KLSL
P
F
L
I
I
L-G
G
----
Y
S
Y
---
F
K
R
F
S
S
L
A
H
--------
F
V
V
---
G
L
A
L
G
L
AP------------------------IAG
S
V
A
V
LGD-----------I
P
L
--------
W
N
V
F
L
A
L
G
V
M
L
W
V
A
G
F
D
---
L
L
Y
S
L
QDME
F
D
KER
G
---
L
F
S
I
P
S
Q
L
G
E
K
W
C
L
N
L
S
R
L
S
H
L
V
A
L
I
C
---
W
L
C
F
V
K
C
YHG
G
L
F
A
Y
L
G
L
G
V
S
A
L
I
L
L
Y
E
Q
I
L
V
A
R
-
D
Y
K-NI
P
K
A
F
F
VSNG
Y
L
G
V
----
V
F
F
I
F
I
--------
V
L
DVGFKHA---------
20
Fugue
91.12
33%
-142
* C4 *
4OD4
-
?
A:
[22-296]
------------------------------------------------------------
L
V
R
I
E
H
T
I
F
S
L
P
F
A
Y
V
G
A
L
L
S
R
Y
P
------
F
T
L
A
D
A
I
L
M
A
A
A
V
V
G
L
R
M
A
G
M
A
Y
N
----
N
I
A
D
------
L
D
I
D
R
--
L
N
P
R
T
A
K
-----
R
--
P
L
V
V
G
A
V
S
L
---
R
E
--
A
W
A
L
V
A
---
A
G
S
A
--
I
--------------
Y
F
A
-----
S
A
A
L
L
-----
N
T
Y
A
L
L
L
S
P
L
V
L
A
I
A
-
L
T
----
Y
P
H
---
A
K
R
L
H
P
L
P
H
--------
L
H
L
---
G
I
V
L
G
S
V
V
------------------------
F
G
G
A
V
A
A
S
G
D
-----------
E
A
S
S
L
G
E
V
L
R
S
V
P
W
L
Y
V
A
A
V
S
L
W
V
A
G
F
D
---
T
I
Y
S
I
M
D
I
D
F
D
R
S
H
G
---
L
G
S
I
P
A
L
L
G
P
K
G
A
L
A
A
S
L
A
M
H
A
A
A
V
A
L
---
F
I
A
G
V
E
A
Y
G
L
G
A
I
A
T
V
S
T
A
L
T
A
L
V
I
I
L
V
Q
A
M
A
W
----
L
-
G
R
V
K
E
S
F
N
L
N
L
A
V
P
I
----
I
I
G
A
G
I
--------
I
V
D
M
L
-------------
1
PsiBlast_PDB
83.94
33%
-136
- C4 -
4OD4
-
?
A:
[22-267]
------------------------------------------------------------
L
V
R
I
E
H
T
I
F
S
L
P
F
A
Y
V
G
A
L
L
S
R
Y
P
------
F
T
L
A
D
A
I
L
M
A
A
A
V
V
G
L
R
M
A
G
M
A
Y
N
----
N
I
A
D
------
L
D
I
D
R
--
L
N
P
R
T
A
K
-----
R
--
P
L
V
V
G
A
V
S
L
---
R
E
--
A
W
A
L
V
A
---
A
G
S
A
--
I
--------------
Y
F
A
-----
S
A
A
L
L
-----
N
T
Y
A
L
L
L
S
P
L
V
L
A
I
A
-
L
T
----
Y
P
H
---
A
K
R
L
H
P
L
P
H
--------
L
H
L
---
G
I
V
L
G
S
V
V
------------------------
F
G
G
A
V
A
A
S
G
D
EASS
L
G
E
V
L
R
S
V
P
---------
W
-
L
Y
V
A
-
A
V
S
L
W
V
A
G
F
D
---
T
I
Y
S
I
M
D
I
D
F
D
R
S
H
G
---
L
G
S
I
P
A
L
L
G
P
K
G
A
L
A
A
S
L
A
M
H
A
A
A
V
A
L
---
F
I
A
G
V
E
A
Y
G
L
G
A
I
A
T
V
S
T
A
L
T
A
L
V
I
I
L
V
Q
A
M
A
W
L
-
G
R
V
-
K
E
S
F
N
L
N
L
A
V
P
I
I
I
G
----
A
G
I
I
V
D
--------
M
L
----------------
12
PsiBlast_CBE
83.43
33%
-135
- C4 -
4OD5
3
?
B:
[21-267]
-----------------------------------------------------------
R
L
V
R
I
E
H
T
I
F
S
L
P
F
A
Y
V
G
A
L
L
S
R
Y
P
------
F
T
L
A
D
A
I
L
M
A
A
A
V
V
G
L
R
M
A
G
M
A
Y
N
----
N
I
A
D
------
L
D
I
D
R
--
L
N
P
R
T
A
K
-----
R
--
P
L
V
V
G
A
V
S
L
---
R
E
--
A
W
A
L
V
A
---
A
G
S
A
--
I
--------------
Y
F
A
-----
S
A
A
L
L
-----
N
T
Y
A
L
L
L
S
P
L
V
L
A
I
A
-
L
T
----
Y
P
H
---
A
K
R
L
H
P
L
P
H
--------
L
H
L
---
G
I
V
L
G
S
V
V
------------------------
F
G
G
A
V
A
A
S
G
D
EASSLGEVLRS
V
P
---------
W
-
L
Y
V
A
-
A
V
S
L
W
V
A
G
F
D
---
T
I
Y
S
I
M
D
I
D
F
D
R
S
H
G
---
L
G
S
I
P
A
L
L
G
P
K
G
A
L
A
A
S
L
A
M
H
A
A
A
V
A
L
---
F
I
A
G
V
E
A
Y
G
L
G
A
I
A
T
V
S
T
A
L
T
A
L
V
I
I
L
V
Q
A
M
A
W
L
-
G
R
V
-
K
E
S
F
N
L
N
L
A
V
P
I
I
I
G
----
A
G
I
I
V
D
--------------------------
9
PsiBlast_CBE
83.05
33%
-136
- C4 -
4OD5
4
?
E:
[21-267]
-----------------------------------------------------------
R
L
V
R
I
E
H
T
I
F
S
L
P
F
A
Y
V
G
A
L
L
S
R
Y
P
------
F
T
L
A
D
A
I
L
M
A
A
A
V
V
G
L
R
M
A
G
M
A
Y
N
----
N
I
A
D
------
L
D
I
D
R
--
L
N
P
R
T
A
K
-----
R
--
P
L
V
V
G
A
V
S
L
---
R
E
--
A
W
A
L
V
A
---
A
G
S
A
--
I
--------------
Y
F
A
-----
S
A
A
L
L
-----
N
T
Y
A
L
L
L
S
P
L
V
L
A
I
A
-
L
T
----
Y
P
H
---
A
K
R
L
H
P
L
P
H
--------
L
H
L
---
G
I
V
L
G
S
V
V
------------------------
F
G
G
A
V
A
A
S
G
D
EASSLGEVLRS
V
P
---------
W
-
L
Y
V
A
-
A
V
S
L
W
V
A
G
F
D
---
T
I
Y
S
I
M
D
I
D
F
D
R
S
H
G
---
L
G
S
I
P
A
L
L
G
P
K
G
A
L
A
A
S
L
A
M
H
A
A
A
V
A
L
---
F
I
A
G
V
E
A
Y
G
L
G
A
I
A
T
V
S
T
A
L
T
A
L
V
I
I
L
V
Q
A
M
A
W
L
-
G
R
V
-
K
E
S
F
N
L
N
L
A
V
P
I
I
I
G
----
A
G
I
I
V
D
--------------------------
2
PsiBlast_PDB
83.04
33%
-135
- C4 -
4OD5
3
?
A:
[21-267]
-----------------------------------------------------------
R
L
V
R
I
E
H
T
I
F
S
L
P
F
A
Y
V
G
A
L
L
S
R
Y
P
------
F
T
L
A
D
A
I
L
M
A
A
A
V
V
G
L
R
M
A
G
M
A
Y
N
----
N
I
A
D
------
L
D
I
D
R
--
L
N
P
R
T
A
K
-----
R
--
P
L
V
V
G
A
V
S
L
---
R
E
--
A
W
A
L
V
A
---
A
G
S
A
--
I
--------------
Y
F
A
-----
S
A
A
L
L
-----
N
T
Y
A
L
L
L
S
P
L
V
L
A
I
A
-
L
T
----
Y
P
H
---
A
K
R
L
H
P
L
P
H
--------
L
H
L
---
G
I
V
L
G
S
V
V
------------------------
F
G
G
A
V
A
A
S
G
D
EASS
L
G
E
V
L
R
S
V
P
---------
W
-
L
Y
V
A
-
A
V
S
L
W
V
A
G
F
D
---
T
I
Y
S
I
M
D
I
D
F
D
R
S
H
G
---
L
G
S
I
P
A
L
L
G
P
K
G
A
L
A
A
S
L
A
M
H
A
A
A
V
A
L
---
F
I
A
G
V
E
A
Y
G
L
G
A
I
A
T
V
S
T
A
L
T
A
L
V
I
I
L
V
Q
A
M
A
W
L
-
G
R
V
-
K
E
S
F
N
L
N
L
A
V
P
I
I
I
G
----
A
G
I
I
V
D
--------------------------
10
PsiBlast_CBE
82.98
33%
-136
- C4 -
4OD5
3
?
D:
[21-267]
-----------------------------------------------------------
R
L
V
R
I
E
H
T
I
F
S
L
P
F
A
Y
V
G
A
L
L
S
R
Y
P
------
F
T
L
A
D
A
I
L
M
A
A
A
V
V
G
L
R
M
A
G
M
A
Y
N
----
N
I
A
D
------
L
D
I
D
R
--
L
N
P
R
T
A
K
-----
R
--
P
L
V
V
G
A
V
S
L
---
R
E
--
A
W
A
L
V
A
---
A
G
S
A
--
I
--------------
Y
F
A
-----
S
A
A
L
L
-----
N
T
Y
A
L
L
L
S
P
L
V
L
A
I
A
-
L
T
----
Y
P
H
---
A
K
R
L
H
P
L
P
H
--------
L
H
L
---
G
I
V
L
G
S
V
V
------------------------
F
G
G
A
V
A
A
S
G
D
EASSLGEVLRS
V
P
---------
W
-
L
Y
V
A
-
A
V
S
L
W
V
A
G
F
D
---
T
I
Y
S
I
M
D
I
D
F
D
R
S
H
G
---
L
G
S
I
P
A
L
L
G
P
K
G
A
L
A
A
S
L
A
M
H
A
A
A
V
A
L
---
F
I
A
G
V
E
A
Y
G
L
G
A
I
A
T
V
S
T
A
L
T
A
L
V
I
I
L
V
Q
A
M
A
W
L
-
G
R
V
-
K
E
S
F
N
L
N
L
A
V
P
I
I
I
G
----
A
G
I
I
V
D
--------------------------
8
PsiBlast_CBE
82.95
33%
-135
- C4 -
4OD5
3
?
F:
[21-267]
-----------------------------------------------------------
R
L
V
R
I
E
H
T
I
F
S
L
P
F
A
Y
V
G
A
L
L
S
R
Y
P
------
F
T
L
A
D
A
I
L
M
A
A
A
V
V
G
L
R
M
A
G
M
A
Y
N
----
N
I
A
D
------
L
D
I
D
R
--
L
N
P
R
T
A
K
-----
R
--
P
L
V
V
G
A
V
S
L
---
R
E
--
A
W
A
L
V
A
---
A
G
S
A
--
I
--------------
Y
F
A
-----
S
A
A
L
L
-----
N
T
Y
A
L
L
L
S
P
L
V
L
A
I
A
-
L
T
----
Y
P
H
---
A
K
R
L
H
P
L
P
H
--------
L
H
L
---
G
I
V
L
G
S
V
V
------------------------
F
G
G
A
V
A
A
S
G
D
EASSLGEVLRS
V
P
---------
W
-
L
Y
V
A
-
A
V
S
L
W
V
A
G
F
D
---
T
I
Y
S
I
M
D
I
D
F
D
R
S
H
G
---
L
G
S
I
P
A
L
L
G
P
K
G
A
L
A
A
S
L
A
M
H
A
A
A
V
A
L
---
F
I
A
G
V
E
A
Y
G
L
G
A
I
A
T
V
S
T
A
L
T
A
L
V
I
I
L
V
Q
A
M
A
W
L
-
G
R
V
-
K
E
S
F
N
L
N
L
A
V
P
I
I
I
G
----
A
G
I
I
V
D
--------------------------
11
PsiBlast_CBE
82.51
33%
-136
- C4 -
4OD5
4
?
C:
[21-267]
-----------------------------------------------------------
R
L
V
R
I
E
H
T
I
F
S
L
P
F
A
Y
V
G
A
L
L
S
R
Y
P
------
F
T
L
A
D
A
I
L
M
A
A
A
V
V
G
L
R
M
A
G
M
A
Y
N
----
N
I
A
D
------
L
D
I
D
R
--
L
N
P
R
T
A
K
-----
R
--
P
L
V
V
G
A
V
S
L
---
R
E
--
A
W
A
L
V
A
---
A
G
S
A
--
I
--------------
Y
F
A
-----
S
A
A
L
L
-----
N
T
Y
A
L
L
L
S
P
L
V
L
A
I
A
-
L
T
----
Y
P
H
---
A
K
R
L
H
P
L
P
H
--------
L
H
L
---
G
I
V
L
G
S
V
V
------------------------
F
G
G
A
V
A
A
S
G
D
EASSLGEVLRS
V
P
---------
W
-
L
Y
V
A
-
A
V
S
L
W
V
A
G
F
D
---
T
I
Y
S
I
M
D
I
D
F
D
R
S
H
G
---
L
G
S
I
P
A
L
L
G
P
K
G
A
L
A
A
S
L
A
M
H
A
A
A
V
A
L
---
F
I
A
G
V
E
A
Y
G
L
G
A
I
A
T
V
S
T
A
L
T
A
L
V
I
I
L
V
Q
A
M
A
W
L
-
G
R
V
-
K
E
S
F
N
L
N
L
A
V
P
I
I
I
G
----
A
G
I
I
V
D
--------------------------
21
Fugue
76.50
23%
-141
- C4 -
4TQ3
3
?
A:
[15-301]
----------------------------------------------------------
S
K
Y
L
R
L
L
R
P
V
A
W
L
C
F
L
L
P
Y
A
V
G
F
G
F
G
I
T
P
N
A
--
S
L
Q
H
A
V
L
G
L
L
S
F
A
F
W
M
A
F
S
F
T
I
N
----
A
L
Y
D
------
R
D
V
D
R
LH
D
G
L
N
L
S
M
-----
Q
--
P
L
V
T
G
E
I
S
V
---
R
E
--
A
W
L
Y
C
I
---
A
F
L
A
--
L
--------------
S
L
A
-----
T
A
A
A
I
-----
N
E
K
F
F
L
A
M
L
G
A
N
I
I
G
-
Y
V
----
Y
S
A
PPR
F
K
A
W
P
V
M
D
V
--------
I
C
N
---
A
L
A
A
V
L
A
F
------------------------
Y
A
G
L
S
I
G
G
A
E
-----------
V
P
-----------
I
A
I
Y
P
A
A
F
F
L
A
A
T
F
Y
---
I
P
T
A
V
S
D
Y
E
F
D
K
K
A
G
---
L
K
N
T
P
V
F
F
G
P
E
R
A
L
K
S
L
Y
P
L
S
A
I
T
V
I
L
---
W
A
Y
V
F
L
M
A
E
R
I
E
I
K
V
I
S
P
L
I
I
A
Y
T
L
I
Y
T
F
I
I
N
S
R
W
D
G
E
-
K
L
N
V
S
P
N
L
I
L
T
P
F
G
I
----
I
S
A
L
F
I
--------
A
Y
G
F
A
V
I
S
V
---------
26
Fugue
59.26
22%
-126
- C3 -
3ACP
-
RPN14_YEAST
A:
[1-417]
MT
K
T
I
T
V
A
H
I
QYD
F
K
A
V
L
E
ENDE
N
D
D
E
F
Y
I
N
V
D
KN
L
N
E
I
K
E
H
K
I
V
V
L
GNSRGVDAGKG
N
T
F
E
K
V
G
S
H
L
Y
K
A
R
L
D
G
H
D
F
L
F
N
T
I
I
R
D
G
S
K
M
L
K
R
A
D
Y
T
A
V
D
T
A
K
L
Q
M
R
R
F
I
L
G
T
T
EG
D
I
K
V
L
D
SNFNLQ
R
E
I
D
Q
AH
V
S
E
I
T
K
L
-----
K
F
F
P
S
G
E
A
L
I
S
S
SQD
M
Q
--
L
K
I
W
S
V
KDG
S
N
P
R
--
T
--------------
L
I
G
HRATV
T
D
I
A
I
I
DRGR
N
V
L
S
A
S
L
D
G
T
I
R
L
W
E
-
C
G
TGTT
I
H
T
---
F
N
R
K
E
N
P
H
D
--------
G
V
N
---
S
I
A
L
F
V
G
T
DRQLHEIST
S
K
K
N
N
LEFGTYG
K
Y
V
I
A
G
H
V
S
--
G
V
-----------
I
T
V
--------
H
N
V
F
S
K
E
Q
T
I
Q
L
P
S
K
F
T
---
C
--
S
C
N
S
L
T
V
D
G
N
N
A
N
Y
I
Y
A
G
Y
E
N
G
M
L
A
Q
W
D
L
R
S
P
E
C
P
V
G
E
F
L
I
N
EGT
P
I
N
N
V
Y
F
A
A
G
A
L
F
V
S
S
G
F
D
T
S
I
K
L
D
I
I
S
D
P
E
S
E
R
-
P
A
I
-
E
F
E
T
P
T
F
L
V
S
N
D
D
E
V
----
S
Q
F
C
Y
V
SDDES
N
G
E
V
L
E
V
G
K
N
N
F
C
A
L
Y
N
LSNP
4
PsiBlast_PDB
57.40
27%
-108
- C4 -
4TQ4
3
?
A:
[63-234]
------------------------------------------------------------------------------------------------------------
F
S
F
T
I
N
----
A
L
Y
D
------
R
D
V
D
R
L-
H
D
G
R
V
K
D
LNLSM
Q
--
P
L
V
T
G
E
I
S
V
---
R
E
--
A
W
L
Y
C
I
---
A
F
L
A
--
L
--------------
S
L
A
-----
T
A
A
A
I
-----
N
E
K
F
F
L
A
M
L
G
A
N
I
I
G
-
Y
V
----
Y
S
A
---
P
P
R
F
K
A
W
P
V
--------
M
D
V
I
C
N
A
L
A
A
V
L
A
F
------------------------
Y
A
G
L
S
I
G
G
A
E
-----------
V
P
-----------
I
A
I
Y
P
A
A
F
F
L
A
A
T
F
Y
---
I
P
T
A
V
S
D
Y
E
F
D
K
K
A
G
---
L
K
N
T
P
V
F
F
G
P
E
R
A
L
K
S
L
Y
P
L
S
A
I
T
V
I
L
---
W
A
Y
V
F
L
M
A
E
R
I
E
I
K
V
I
S
P
L
I
I
A
Y
T
L
I
Y
T
F
I
I
N
S
R
-
W
D
G
-
E
K
L
N
V
S
P
N
L
I
L
T
P
F
G
----
I
I
S
A
L
F
--------
I
A
Y
G
F
A
V
I
S
---------
3
PsiBlast_PDB
56.23
27%
-112
- C4 -
4TQ3
3
?
A:
[63-234]
------------------------------------------------------------------------------------------------------------
F
S
F
T
I
N
----
A
L
Y
D
------
R
D
V
D
R
L-
H
D
G
----LNLSM
Q
--
P
L
V
T
G
E
I
S
V
---
R
E
--
A
W
L
Y
C
I
---
A
F
L
A
--
L
--------------
S
L
A
-----
T
A
A
A
I
-----
N
E
K
F
F
L
A
M
L
G
A
N
I
I
G
-
Y
V
----
Y
S
A
---
P
P
R
F
K
A
W
P
V
--------
M
D
V
I
C
N
A
L
A
A
V
L
A
F
------------------------
Y
A
G
L
S
I
G
G
A
E
-----------
V
P
-----------
I
A
I
Y
P
A
A
F
F
L
A
A
T
F
Y
---
I
P
T
A
V
S
D
Y
E
F
D
K
K
A
G
---
L
K
N
T
P
V
F
F
G
P
E
R
A
L
K
S
L
Y
P
L
S
A
I
T
V
I
L
---
W
A
Y
V
F
L
M
A
E
R
I
E
I
K
V
I
S
P
L
I
I
A
Y
T
L
I
Y
T
F
I
I
N
S
R
-
W
D
G
-
E
K
L
N
V
S
P
N
L
I
L
T
P
F
G
----
I
I
S
A
L
F
--------
I
A
Y
G
F
A
V
I
S
---------
25
Fugue
41.42
13%
-151
- C5 -
4Q7O
8
?
A:
[4-136]
--------------------------------------------
M
K
N
-----------
N
I
F
L
N
L
N
K
K
S
I
N
N
N
H
F
V
I
S
I
F
F
E
T
I
Y
Q
F
E
T
----
K
D
T
L
L
E
C
F
K
N
I
T
T
T
G
H
F
G
V
--
I
----
G
A
Q
Y
------
E
K
I
D
A
---
T
R
W
I
G
D
-----
Y
--
E
E
V
N
G
F
E
Y
I
---
D
K
AP
S
I
Y
F
S
V
---
G
D
D
F
NP
E
--------------
E
L
I
-----
I
P
I
N
L
-----
A
Y
H
Y
F
N
I
A
I
S
D
F
L
I
A
-
H
-----
P
E
Y
---
Q
K
K
C
K
E
I
Q
K
--------
T
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
39.34
16%
-84
* C5 *
4AUI
6
?
A:
[20-327]
------------------------------------
D
V
T
L
Y
G
T
I
K
A
G
-----------
V
E
T
S
R
S
V
A
H
H
G
A
Q
A
D
R
V
K
T
A
T
E
I
A
D
L
G
S
K
I
G
F
K
G
Q
E
D
L
---------
G
N
G
L
K
A
I
W
Q
----
L
E
Q
K
------
A
Y
V
S
G
--
T
D
T
G
W
G
N
-----
R
--
Q
S
F
I
G
L
K
G
G
---
F
G
--
K
V
R
V
G
R
---
L
N
N
I
--
L
K
D
T
GNFNPWEGKSY
Y
S
G
-----
L
S
N
I
A
-----
Q
P
E
E
R
H
V
S
V
R
Y
D
S
P
E
F
A
G
----
F
S
G
---
S
V
Q
Y
V
P
N
D
N
SGKNRS
E
S
Y
H
A
---
G
F
N
Y
K
N
D
G
------------------------
F
F
V
Q
Y
A
G
S
Y
K
-----------
R
H
N
--------
Y
T
T
-
E
K
H
Q
V
H
R
L
V
G
G
Y
D
HDA
L
Y
A
S
V
A
V
Q
Q
Q
D
A
K
L
T
---
W
R
D
D
N
S
H
N
S
Q
T
E
V
A
T
T
V
A
Y
R
F
G
-
N
V
T
P
---
R
V
S
Y
A
H
G
F
K
G
S
V
------
Y
D
A
D
H
D
N
T
Y
D
Q
V
V
V
G
A
-
E
Y
D
F
S
K
R
T
S
A
L
V
S
A
G
W
L
Q
K
G
KGA
E
K
F
V
A
T
--------
V
G
G
V
G
L
R
H
K
F--------
6
PsiBlast_PDB
31.03
28%
-2
- C6 -
2Z5Y
1
AOFA_HUMAN
A:
[445-507]
---------------------------------------------------------------------------------------------------------
A
R
E
V
L
N
G
L
G
----
K
V
T
E
------
K
D
I
W
V
--
Q
E
P
E
S
K
D
-----
V
--
P
A
V
E
I
T
H
T
F
---
W
E
--
R
N
L
P
S
V
---
S
G
L
L
--
K
--------------
I
I
G
-----
F
S
T
S
V
-----
T
A
L
G
F
V
L
Y
K
Y
K
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
30.96
28%
-2
* C6 *
2Z5X
2
AOFA_HUMAN
A:
[445-507]
---------------------------------------------------------------------------------------------------------
A
R
E
V
L
N
G
L
G
----
K
V
T
E
------
K
D
I
W
V
--
Q
E
P
E
S
K
D
-----
V
--
P
A
V
E
I
T
H
T
F
---
W
E
--
R
N
L
P
S
V
---
S
G
L
L
--
K
--------------
I
I
G
-----
F
S
T
S
V
-----
T
A
L
G
F
V
L
Y
K
Y
K
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
29.90
28%
67
- C6 -
2BXS
-
AOFA_HUMAN
A:
[456-506]
---------------------------------------------------------------------------------------------------------
A
R
E
V
L
N
G
L
G
----
K
V
T
E
------
K
D
I
W
V
--
Q
E
P
E
S
K
D
-----
V
--
P
A
V
E
I
T
H
T
F
---
W
E
--
R
N
L
P
S
V
---
S
G
L
L
--
K
--------------
I
I
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
28.04
31%
658
- C4 -
3UKW
1
?
C:
[13-25]
-------------------------------------------------------------------------------------------------------------------------
E
------
W
D
E
D
E
--
E
P
P
R
K
R
K
-----
R
--
L
W
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
25.07
25%
14
- C4 -
1IFP
-
?
?:
[1-44]
-----------------------------------
M
Q
S
V
I
T
D
V
T
G
Q
L
-----------
T
A
V
Q
A
D
I
T
T
I
G
G
A
I
I
V
L
A
A
V
V
L
G
I
R
W
I
K
A
Q
F
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
23.99
12%
38
- C4 -
1V4E
1
?
A:
[67-91]
---------------------------------------------------------------------------------------------------
L
A
A
L
E
L
V
H
L
A
S
L
L
H
D
----
D
V
I
D
------
G
A
R
F
R
--
R
G
K
E
T
I
N
-----
F
--
M
Y
G
D
K
A
A
V
A
---
A
G
--
D
L
V
L
V
S
---
A
F
H
T
--
V
--------------
E
E
I
-----
G
N
N
K
L
-----
R
R
A
F
L
N
V
I
G
K
M
S
E
A
E
-
L
I
----
E
Q
L
---
S
R
Y
K
P
I
T
K
E
--------
E
Y
L
---
R
I
V
E
G
K
S
G
------------------------
A
L
F
G
L
A
L
Q
L
P
-----------
A
L
L
--------
E
G
E
L
G
E
D
L
Y
N
L
G
V
T
I
G
T
---
I
Y
Q
M
F
D
D
I
M
D
F
A
G
M
E
---
K
I
G
K
D
G
F
L
D
L
K
N
G
V
A
S
F
P
L
V
T
A
M
E
K
F
P
---
E
A
R
Q
M
F
E
N
R
D
W
S
G
L
M
S
F
M
R
E
K
G
I
L
K
E
C
E
E
T
L
K
V
L
-
V
K
N
-
V
I
I
E
N
S
W
L
R
D
F
----------------------------------------