@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0227: (2016-03-13 )
MFKIGNVEIKNQVVVAPMAGISNSAFRLTVKEFGAGLVCCEMISDKGIAYRNAKTLDMLYIDEKEKPLSLQIFGGEKETLVEAAKFVAENTTADIIDINMGCPVNKIIKCEAGAKWLLDPNKVYDMVAAVVDAVDKPVTVKMRIGWDEEHVFAIENALAAERAGAAAVAMHGRTRVQMYEGSANWDVLRDVKRELKIPFMANGDVRTPEDAKRILEHTGADGVMIGRAALGNPWMIYRTVKFLETGELLLEPEPREKMQTAMLHLNRLVELKGENIAVREFRQHAAYYLKGARGSTRAKVAANQATKQSEMEAILNEFVLQYEEKALAKQD
Atome Classification :
(20 SA)
.........10......-..20--------..-----..----....30--.-------....-.-..-------40-.....---------------------..--.50-.--------------------.------------------.-----------.---..-...---60----........70....------------------------..----------------------..80........90..-......100--------.---------.......110.......120.......130..--..--...140.....----.----.--150.--......160.......170...----------------------.----------------.--..----180---.----.----....--..-190...--.-----...200.......210.......220.......230........240.......250.......260.......270...----....280........290.......300-.......310-.......320.......330
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MFKIG
N
V
E
I
K
N
Q
V
V
V
A
P-MAGI--------SN-----S
A
----
F
R
L
T
V
K
--
E
-------FG
A
G
-
L
-
V
C
-------
C
E
-
M
ISDK---------------------GI--AY--R--------------------N------------------A-----------
K
---
T
L
-
D
M
L
---
Y
I----DEKEK
P
L
S
L
Q
I
FGG------------------------
E
K
----------------------
E
T
L
V
E
A
A
K
F
V
AENTTA-
D
I
I
D
INMG---------C---------PVN
K
I
I
KCEAG
A
K
WLL
D
P
N
K
V
Y
D
M
V
A
A
V
V
DAV--DK--
P
V
T
V
K
M
R
IGWD----E----
E
--
H
V
F
A
--
I
E
N
A
L
A
A
ERAG
A
A
A
V
A
MHG
R
T
R
----------------------
V
----------------
Q
--
M
Y----EG----S----A----
N
W
D
V
--
L
R
-
D
V
K
R
EL--K-----I
P
F
MANGDVR
T
P
E
D
A
K
R
I
L
E
HTGAD
G
V
M
I
GRAALG-N
P
W
M
I
Y
R
T
V
K
F
LETG
E
L
L
LEPE
P
R
E
K
M
Q
T
A
M
L
H
L
N
R
L
V
E
LKGEN----
I
A
V
R
E
F
-
R
Q
H
A
A
Y
Y
L
KGARGST
R
A
K
V
AA-NQAT
K
Q
S
E
M
E
-
A
I
L
N
E
F
V
L
Q
Y
E
E
K
A
LAKQD
81
HHSearch
94.96
35%
-92
- C2 -
1VHN
4
?
A:
[5-309]
----------
V
K
V
G
L
A
P
-
M
A
G
Y
--------
T
D
-----
S
A
----
F
R
T
L
A
F
--
E
-------
W
G
A
D
-
F
-
A
F
-------
S
E
-
M
V
S
A
K
---------------------
G
F
--
L
M
--
N
--------------------
S
------------------
Q
-----------
K
---
T
E
-
E
L
L
----
P
----
Q
P
H
E
R
N
V
A
V
Q
I
F
G
S
------------------------
E
P
----------------------
N
E
L
S
E
A
A
R
I
L
S
E
--
K
Y
-
K
W
I
D
L
N
A
G
---------
C
---------
P
V
R
K
V
V
K
E
G
A
G
G
A
L
L
K
D
L
R
H
F
R
Y
I
V
R
E
L
R
K
S
V
--
S
G
--
K
F
S
V
K
T
R
L
G
W
E
----
K
--------
N
E
V
--
E
E
I
Y
R
I
L
V
E
E
G
V
D
E
V
F
I
H
T
R
T
V
----------------------
V
----------------
Q
--
S
F
----
T
G
----
R
----
A
----
E
W
K
A
--
L
S
-
V
L
E
K
----
R
-----
I
P
T
F
V
S
G
D
I
F
T
P
E
D
A
K
R
A
L
E
E
S
G
C
D
G
L
L
V
A
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G
A
I
G
-
R
P
W
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F
K
Q
I
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D
F
L
R
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K
-
Y
S
E
P
S
R
E
E
I
L
R
T
F
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R
H
L
E
L
L
I
K
T
K
G
E
R
----
K
A
V
V
E
M
-
R
K
F
L
A
G
Y
T
K
D
L
K
G
A
R
R
F
R
E
K
V
-
M
K
I
E
E
V
Q
I
L
K
-
E
M
F
Y
N
F
I
K
E
V
E
--------
1
PsiBlast_PDB
91.29
37%
-95
- C2 -
1VHN
4
?
A:
[6-285]
-----------
K
V
G
L
A
P
-
M
A
G
Y
--------
T
D
-----
S
A
----
F
R
T
L
A
F
--
E
-------
W
G
A
D
-
F
-
A
F
-------
S
E
-
M
V
S
A
K
---------------------
G
F
--
L
M
--
N
--------------------
S
------------------
Q
-----------
K
---
T
E
-
E
L
L
----
P
----
Q
P
H
E
R
N
V
A
V
Q
I
F
G
S
------------------------
E
P
----------------------
N
E
L
S
E
A
A
R
I
L
S
E
K
Y
---
K
W
I
D
L
N
A
G
---------
C
---------
P
V
R
K
V
V
K
E
G
A
G
G
A
L
L
K
D
L
R
H
F
R
Y
I
V
R
E
L
R
K
S
V
--
S
G
--
K
F
S
V
K
T
R
L
G
W
E
----
K
----
N
--
E
V
E
E
--
I
Y
R
I
L
V
E
E
--
G
V
D
E
V
F
I
H
T
R
T
V
----------------------
V
----------------
Q
--
S
F
----
T
G
----
R
----
A
----
E
W
K
A
--
L
S
-
V
L
--
E
K
--
R
-----
I
P
T
F
V
S
G
D
I
F
T
P
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D
A
K
R
A
L
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E
S
G
C
D
G
L
L
V
A
R
G
A
I
G
-
R
P
W
I
F
K
Q
I
K
D
F
L
R
S
G
K
-
Y
S
E
P
S
R
E
E
I
L
R
T
F
E
R
H
L
E
L
L
I
K
T
K
G
E
R
----
K
A
V
V
E
M
-
R
K
F
L
A
G
Y
T
K
D
L
K
G
A
R
R
F
R
----------------------------------
104
Fugue
86.37
34%
-80
- C2 -
1VHN
4
?
A:
[5-309]
----------
V
K
V
G
L
A
P
M
A
-
G
Y
--------
T
D
-----
S
A
----
F
R
T
L
A
F
--
E
-------
W
G
A
D
-
F
-
A
F
-------
S
E
M
V
S
A
K
G
---------------------
F
L
M
-
N
S
--
Q
--------------------
K
------------------
T
-----------
E
---
E
L
-
L
P
----------
Q
P
H
E
R
N
V
A
V
Q
I
F
G
S
------------------------
E
P
----------------------
N
E
L
S
E
A
A
R
I
L
S
E
K
--
Y
-
K
W
I
D
L
N
A
G
---------
C
---------
P
V
R
K
V
V
K
E
G
A
G
G
A
L
L
K
D
L
R
H
F
R
Y
I
V
R
E
L
R
K
S
V
--
S
G
--
K
F
S
V
K
T
R
L
G
W
E
----
K
----
N
--
E
V
E
E
--
I
Y
R
I
L
V
E
--
E
G
V
D
E
V
F
I
H
T
R
T
V
----------------------
V
----------------
Q
--
S
F
----
T
G
----
R
----
A
----
E
W
K
A
--
L
S
-
V
L
E
K
R
---------
I
P
T
F
V
S
G
D
I
F
T
P
E
D
A
K
R
A
L
E
E
S
G
C
D
G
L
L
V
A
R
G
A
I
G
-
R
P
W
I
F
K
Q
I
K
D
F
L
R
S
G
K
Y
S
-
E
P
S
R
E
E
I
L
R
T
F
E
R
H
L
E
L
L
I
K
T
K
G
E
R
----
K
A
V
V
E
-
M
R
K
F
L
A
G
Y
T
K
D
L
K
G
A
R
R
F
R
E
K
V
M
K
I
E
E
V
Q
I
L
K
E
M
F
----------
Y
N
F
I
K
E
V
E
106
Fugue
80.81
27%
-79
- C2 -
4BFA
6
DUSC_ECOLI
A:
[22-338]
--------
A
S
M
R
V
L
L
A
P
-
M
E
G
V
--------
L
D
-----
S
L
----
V
R
E
L
L
T
--
E
V
N
DYD
L
C
I
T
E
F
-
V
-
R
V
-------
V
D
-
Q
L
L
P
V
---------------------
K
V
--
F
H
--
R
--------------------
I
------------------
C
-----------
P
---
E
L
-
Q
N
A
---
S
R
----
T
P
S
G
T
L
V
R
V
Q
L
L
G
Q
------------------------
F
P
----------------------
Q
W
L
A
E
N
A
A
R
A
V
E
L
G
S
W
-
G
-
V
D
L
N
C
G
---------
C
---------
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
PA
H
L
--
P
V
S
V
K
V
R
L
G
W
D
----
S
----
G
--
E
K
-
K
--
F
E
I
A
D
A
V
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
----------------------
E
----------------
Q
--
G
Y
----
R
A
----
E
----
H
I---
D
W
Q
A
--
I
G
-
D
I
R
Q
R
L
--
N
-----
I
P
V
I
A
N
G
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
-
I
P
-
N
L
S
R
V
V
K
Y
---------
N
E
P
R
M
P
W
P
E
V
V
A
L
L
Q
K
Y
T
R
L
E
K
Q
G
DTGL
Y
H
V
A
R
I
-
K
Q
W
L
S
Y
L
R
K
E
Y
D
E
A
T
E
L
F
Q
H
V
-
R
V
L
N
N
S
P
D
I
A
-
R
A
I
Q
A
I
D
I
E
K
L
--------
82
HHSearch
78.92
25%
-94
- C2 -
3B0P
1
DUSAL_THET8
A:
[2-318]
--------
L
D
P
R
L
S
V
A
P
-
M
V
D
R
--------
T
D
-----
R
H
----
F
R
F
L
V
R
--
Q
-------
V
S
L
G
-
V
R
L
Y
-------
T
E
-
M
T
V
D
Q
---------------------
A
V
--
L
R
--
G
--------------------
N
------------------
R
-----------
E
------
R
L
L
---
A
F
----
R
P
E
E
H
P
I
A
L
Q
L
A
G
S
------------------------
D
P
----------------------
K
S
L
A
E
A
A
R
I
G
E
A
-
F
G
Y
-
D
E
I
N
L
N
L
G
---------
C
---------
P
S
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K
A
Q
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G
Y
G
A
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L
L
L
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L
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--
R
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--
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V
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V
K
M
R
L
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L
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----
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----
K
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Y
R
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--
A
Q
S
V
E
A
M
A
E
A
G
V
K
V
F
V
V
H
A
R
S
A
----------------------
L
---------------------------IP--
P
----
L
----
R
H
D
W
--
V
H
-
R
L
K
G
D
F
P-
Q
-----
L
T
F
V
T
N
G
G
I
R
S
L
E
E
A
L
F
H
L
K
--
R
V
D
G
V
M
L
G
R
A
V
Y
E
-
D
P
F
V
L
E
E
A
D
R
R
V
F
G
L
--
P
R
R
P
S
R
L
E
V
A
R
R
M
R
A
Y
L
E
E
E
V
L
K
G
T
-------
P
P
W
A
V
-
L
R
H
M
L
N
L
F
R
G
R
P
K
G
R
L
W
R
R
L
L
-
S
E
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R
S
L
Q
A
L
D
-
R
A
L
R
L
M
E
E
E
V
G
E
-------
105
Fugue
75.94
25%
-89
- C2 -
3B0P
1
DUSAL_THET8
A:
[2-318]
--------
L
D
P
R
L
S
V
A
P
-
M
V
D
R
--------
T
D
-----
R
H
----
F
R
F
L
V
R
--
Q
-------
V
S
L
G
V
R
-
L
Y
-------
T
E
-
M
T
V
D
Q
---------------------
A
V
--
L
R
--
G
--------------------
N
----------------------------------
R
E
-
R
L
L
---
A
F
----
R
P
E
E
H
P
I
A
L
Q
L
A
G
S
------------------------
D
P
----------------------
K
S
L
A
E
A
A
R
I
G
E
A
F
G
Y
--
D
E
I
N
L
N
L
G
---------
C
---------
P
S
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K
A
Q
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G
Y
G
A
C
L
L
L
D
L
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L
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V
--
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V
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M
R
L
G
L
E
GK--
E
----
T
--
Y
R
G
L
--
A
Q
S
V
E
A
M
A
E
A
G
V
K
V
F
V
V
H
A
R
S
-------------------------------------------
A
L
----
I
P
----
P
----
L
----
R
H
D
W
--
V
H
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R
L
K
G
D
F
P-
Q
-----
L
T
F
V
T
N
G
G
I
R
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L
E
E
A
L
F
H
L
K
R
--
V
D
G
V
M
L
G
R
A
V
Y
E
-
D
P
F
V
L
E
E
A
D
R
R
V
-----
F
G
L
P
R
R
P
S
R
L
E
V
A
R
R
M
R
A
Y
L
E
E
E
V
L
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----
T
P
P
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A
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L
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L
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L
F
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L
-
S
E
G
R
S
L
Q
A
L
D
-
R
A
L
R
L
M
E
E
E
V
G
E
-------
3
PsiBlast_PDB
71.22
30%
-90
- C2 -
4BFA
5
DUSC_ECOLI
A:
[25-264]
-----------
R
V
L
L
A
P
-
M
E
G
V
--------
L
D
-----
S
L
----
V
R
E
L
L
T
--
E
-------
V
N
D
Y
-
D
-
L
C
I
T
EFVRV
V
D
-
Q
L
L
P
V
---------------------
K
V
--
F
H
--
R
--------------------
I
------------------
C
-----------
P
---
E
L
-
Q
N
A
---
S
R
----
T
P
S
G
T
L
V
R
V
Q
L
L
G
Q
------------------------
F
P
----------------------
Q
W
L
A
E
N
A
A
R
A
V
E
L
G
S
W
-
G
V
-
D
L
N
C
G
---------
C
---------
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
--
P
A
H
L
P
V
S
V
K
V
R
L
G
W
D
----
S
G---
E
--
K
K
F
E
--
I
A
D
A
V
--
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
----------------------
E
----------------
Q
--
G
Y
----
R
A
E---
H
----
I
----
D
W
Q
A
--
I
G
-
D
I
R
Q
R
L
--
N
-----
I
P
V
I
A
N
G
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
-
I
P
-
N
L
S
R
V
V
K
Y
N
E
----------------------------------------------------------------------------------------------
2
PsiBlast_PDB
70.47
30%
-90
- C2 -
3W9Z
1
DUSC_ECOLI
A:
[2-252]
-----------
R
V
L
L
A
P
-
M
E
G
V
--------
L
D
-----
S
L
----
V
R
E
L
L
T
--
E
-------
V
N
D
Y
-
D
-
L
C
I
T
EFVRV
V
D
-
Q
L
L
P
V
---------------------
K
V
--
F
H
--
R
--------------------
I
------------------
C
-----------
P
---
E
L
-
Q
N
A
---
S
R
----
T
P
S
G
T
L
V
R
V
Q
L
L
G
Q
------------------------
F
P
----------------------
Q
W
L
A
E
N
A
A
R
A
V
E
L
G
S
W
-
G
V
-
D
L
N
C
G
---------
C
----------------------
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
--
P
A
H
L
P
V
S
V
K
V
R
L
G
W
D
----
S
G---
E
--
K
K
F
E
--
I
A
D
A
V
--
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
----------------------
E
----------------
Q
--
G
Y
----
R
A
E---
H
----
I
----
D
W
Q
A
--
I
G
-
D
I
R
Q
R
L
--
N
-----
I
P
V
I
A
N
G
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
-
I
P
-
N
L
S
R
V
V
K
Y
N
E
----------------------------------------------------------------------------------------------
8
PsiBlast_PDB
70.27
30%
-93
- C2 -
3B0U
3
DUSAL_THET8
X:
[2-235]
--------
L
D
P
R
L
S
V
A
P
-
M
V
D
R
--------
T
D
-----
R
H
----
F
R
F
L
V
R
--
Q
-------
V
S
L
G
-
V
R
L
Y
-------
T
E
-
M
T
V
D
Q
---------------------
A
V
--
L
R
--
G
--------------------
N
------------------
R
-----------
E
---
R
L
---
L
---
A
F
----
R
P
E
E
H
P
I
A
L
Q
L
A
G
S
------------------------
D
P
----------------------
K
S
L
A
E
A
A
R
-
I
G
E
A
F
G
Y
-
D
E
I
N
L
N
L
G
---------
C
---------
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
V
R
E
I
L
K
A
M
G
E
A
V
--
R
V
--
P
V
T
V
K
M
R
L
G
L
E
----
G
----
K
--
E
T
Y
R
GL
A
Q
S
V
E
A
M
A
E
A
G
V
K
V
F
V
V
H
A
R
S
A
----------------------
L
----------------
L
--
A
L
----
S
T
----
K
----
A
----
N
R
E
I
PP
L
R
H
D
W
V
H
R
L
--
K
GDFPQ
L
T
F
V
T
N
G
G
I
R
S
L
E
E
A
--
L
F
H
L
K
R
V
D
G
V
M
L
G
R
A
V
Y
E
-
D
P
F
V
L
------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
69.69
30%
-86
- C2 -
4YCO
1
DUSC_ECOLI
A:
[8-247]
-----------
R
V
L
L
A
P
-
M
E
G
V
--------
L
D
-----
S
L
----
V
R
E
L
L
T
--
E
-------
V
N
D
Y
-
D
-
L
C
I
T
EFVRV
V
D
-
Q
L
L
P
V
---------------------
K
V
--
F
H
--
R
--------------------
I
------------------
C
-----------
P
---
E
L
-
Q
N
A
---
S
R
----
T
P
S
G
T
L
V
R
V
Q
L
L
G
Q
------------------------
F
P
----------------------
Q
W
L
A
E
N
A
A
R
A
V
E
L
G
S
W
-
G
V
-
D
L
N
C
G
---------
A
---------
P
S
----
G
S
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
--
P
A
H
L
P
V
S
V
K
V
R
L
G
W
D
----
S
G---
E
--
K
K
F
E
--
I
A
D
A
V
--
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
----------------------
E
----------------
Q
--
G
Y
----
R
A
E---
H
----
I
----
D
W
Q
A
--
I
G
-
D
I
R
Q
R
L
--
N
-----
I
P
V
I
A
N
G
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
-
I
P
-
N
L
S
R
V
V
K
Y
N
E
----------------------------------------------------------------------------------------------
10
PsiBlast_PDB
69.63
29%
-92
- C2 -
3B0V
1
DUSAL_THET8
C:
[22-256]
-------
M
L
D
P
R
L
S
V
A
P
-
M
V
D
R
--------
T
D
-----
R
H
----
F
R
F
L
V
R
--
Q
-------
V
S
L
G
-
V
R
L
Y
-------
T
E
-
M
T
V
D
Q
---------------------
A
V
--
L
R
--
G
--------------------
N
------------------
R
-----------
E
---
R
L
---
L
---
A
F
----
R
P
E
E
H
P
I
A
L
Q
L
A
G
S
------------------------
D
P
----------------------
K
S
L
A
E
A
A
R
-
I
G
E
A
F
G
Y
-
D
E
I
N
L
N
L
G
---------
C
---------
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
V
R
E
I
L
K
A
M
G
E
A
V
--
R
V
--
P
V
T
V
K
M
R
L
G
L
E
----
G
----
K
--
E
T
Y
R
GL
A
Q
S
V
E
A
M
A
E
A
G
V
K
V
F
V
V
H
A
R
S
A
----------------------
L
----------------
L
--
A
L
----
S
T
----
K
----
A
----
N
R
E
I
PP
L
R
H
D
W
V
H
R
L
--
K
GDFPQ
L
T
F
V
T
N
G
G
I
R
S
L
E
E
A
--
L
F
H
L
K
R
V
D
G
V
M
L
G
R
A
V
Y
E
-
D
P
F
V
L
------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
69.02
30%
-101
- C2 -
3B0P
1
DUSAL_THET8
A:
[2-235]
--------
L
D
P
R
L
S
V
A
P
-
M
V
D
R
--------
T
D
-----
R
H
----
F
R
F
L
V
R
--
Q
-------
V
S
L
G
-
V
R
L
Y
-------
T
E
-
M
T
V
D
Q
---------------------
A
V
--
L
R
--
G
--------------------
N
------------------
R
-----------
E
---
R
L
---
L
---
A
F
----
R
P
E
E
H
P
I
A
L
Q
L
A
G
S
------------------------
D
P
----------------------
K
S
L
A
E
A
A
R
-
I
G
E
A
F
G
Y
-
D
E
I
N
L
N
L
G
---------
C
---------
P
S
E
K
A
Q
E
G
G
Y
G
A
C
L
L
L
D
L
A
R
V
R
E
I
L
K
A
M
G
E
A
V
--
R
V
--
P
V
T
V
K
M
R
L
G
L
E
----
G
----
K
--
E
T
Y
R
G
L
A
Q
S
V
E
A
M
A
E
A
G
V
K
V
F
V
V
H
A
R
S
A
----------------------
L
--------------------------------------------
I
PP
L
R
H
D
W
V
H
R
L
--
K
G
D
F
PQ
L
T
F
V
T
N
G
G
I
R
S
L
E
E
A
--
L
F
H
L
K
R
V
D
G
V
M
L
G
R
A
V
Y
E
-
D
P
F
V
L
------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
68.95
29%
-87
- C2 -
4BF9
1
DUSC_ECOLI
A:
[21-264]
-------
M
A
S
M
R
V
L
L
A
P
-
M
E
G
V
--------
L
D
-----
S
L
----
V
R
E
L
L
T
--
E
-------
V
N
D
Y
-
D
-
L
C
I
T
EFVRV
V
D
-
Q
L
L
P
V
---------------------
K
V
--
F
H
--
R
--------------------
I
------------------
C
-----------
P
---
E
L
-
Q
N
A
---
S
R
----
T
P
S
G
T
L
V
R
V
Q
L
L
G
Q
------------------------
F
P
----------------------
Q
W
L
A
E
N
A
A
R
A
V
E
L
G
S
W
-
G
V
-
D
L
N
C
G
---------
C
---------
P
S
K
T
V
N
G
S
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
--
P
A
H
L
P
V
S
V
K
V
R
L
G
W
D
----
S
G---
E
--
K
K
F
E
--
I
A
D
A
V
--
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
----------------------
E
----------------
Q
--
G
Y
----
R
A
----
E
----
H
I---
D
W
Q
A
--
I
G
-
D
I
R
Q
R
L
--
N
-----
I
P
V
I
A
N
G
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
-
I
P
-
N
L
S
R
V
V
K
Y
N
E
----------------------------------------------------------------------------------------------
6
PsiBlast_PDB
68.31
30%
-82
- C2 -
4YCP
1
DUSC_ECOLI
A:
[8-247]
-----------
R
V
L
L
A
P
-
M
E
G
V
--------
L
D
-----
S
L
----
V
R
E
L
L
T
--
E
-------
V
N
D
Y
-
D
-
L
C
I
T
EFVRV
V
D
-
Q
L
L
P
V
---------------------
K
V
--
F
H
--
R
--------------------
I
------------------
C
-----------
P
---
E
L
-
Q
N
A
---
S
R
----
T
P
S
G
T
L
V
R
V
Q
L
L
G
Q
------------------------
F
P
----------------------
Q
W
L
A
E
N
A
A
R
A
V
E
L
G
S
W
-
G
V
-
D
L
N
C
G
---------
A
---------
P
-------
G
G
G
A
T
L
L
K
D
P
E
L
I
Y
Q
G
A
K
A
M
R
E
A
V
--
P
A
H
L
P
V
S
V
K
V
R
L
G
W
D
----
S
G---
E
--
K
K
F
E
--
I
A
D
A
V
--
Q
Q
A
G
A
T
E
L
V
V
H
G
R
T
K
----------------------
E
----------------
Q
--
G
Y
----
R
A
E---
H
----
I
----
D
W
Q
A
--
I
G
-
D
I
R
Q
R
L
--
N
-----
I
P
V
I
A
N
G
E
I
W
D
W
Q
S
A
Q
Q
C
M
A
I
S
G
C
D
A
V
M
I
G
R
G
A
L
N
-
I
P
-
N
L
S
R
V
V
K
Y
N
E
----------------------------------------------------------------------------------------------
103
HHSearch
65.33
20%
-98
- C2 -
1GTE
2
DPYD_PIG
A:
[535-841]
-
V
E
M
A
G
L
K
F
I
N
P
F
G
L
A
S
-
A
A
P
T
--------
T
S
-----
S
S
----
M
I
R
R
A
F
--
E
-------
A
G
W
G
-
F
-
A
L
-------
T
K
-
T
F
S
L
D
---------------------
K
D
I
V
T
N
V
S
P
R
I
V
R
G
TTSGPMYGPGQS
S
F
L
N
IELISEKT----------
A
-----------
A
---
Y
W
C
Q
S
V
T
E
L
K
A
----
D
F
P
D
N
I
V
I
A
S
I
M
C
S
Y-----------------------
N
K
----------------------
N
D
W
M
E
L
S
R
K
A
E
A
-
S
G
A
-
D
A
L
E
L
N
L
S
---------
C
---------
P
H
G
M
G
------
L
A
C
G
Q
D
P
E
L
V
R
N
I
C
R
W
V
R
Q
A
V
--
Q
I
--
P
F
F
A
K
L
T
P
N
V
T
--------------
D
I
--
V
S
I
A
R
A
A
K
E
G
G
A
D
G
V
T
A
T
N
T
V
S
G
L
MGLKADGTPWPAVGAGKRT
T
Y
----------------
G
--
G
V
----
S
G
----
T
----
A
I
R
P
I
A
L
R
A
--
V
T
-
T
I
A
R
A
L
P-
G
-----
F
P
I
L
A
T
G
G
I
D
S
A
E
S
G
L
Q
F
L
H
-
S
G
A
S
V
L
Q
V
C
S
A
V
Q
N
Q
D
F
T
V
I
Q
D
Y
C
T
G
L
K
----------------------------------------------------------------------------------------------
85
HHSearch
64.49
20%
-94
- C2 -
3KRU
2
?
A:
[7-325]
P
L
K
I
K
D
I
T
I
K
N
R
I
M
M
S
P
-
M
C
M
Y
--------
S
A
STDG-
M
P
N
D
W
H
I
V
H
Y
A
T
R
A
I
-------
G
G
V
G
-
L
-
I
M
-------
Q
E
-
A
T
A
V
E
---------------------
S
R
--
G
R
--
I
TD------------------
H
DLGIWN------------
D
E
Q
V
--------
K
---
E
L
-
K
K
I
V
D
-
I
C
----
K
A
N
G
A
V
M
G
I
Q
L
A
H
A
GRKCNISYEDVVGPSPIKAGDRYK
L
P
RELS
V
E
E
I
K
S
I
V
----------
K
A
F
G
E
A
A
K
R
A
N
L
-
A
G
Y
-
D
V
V
E
I
H
A
A
HGY
L
I
H
E
F
L
S
---------
P
L
S
N
K
R
K
D
E
Y
G
N
S
I
E
N
R
A
R
F
L
I
E
V
I
D
E
V
R
K
N
W
PE
N
K
--
P
I
F
V
R
V
S
A
D
D
Y
----
M
EGGI
N
--
I
D
M
M
--
V
E
Y
I
N
M
I
K
-
D
K
V
D
L
I
D
V
S
S
G
G
L
----------------------
L
----------------
N
VD
I
N
----
L
Y
P---
G
----
Y
----
Q
V
K
Y
--
A
E
-
T
I
K
K
R
C
--
N
-----
I
K
T
S
A
V
G
L
I
T
T
Q
E
L
A
E
E
I
L
S
N
E
R
A
D
L
V
A
L
G
R
E
L
L
R
-
N
P
Y
W
V
L
H
T
Y
T
S
K
E
----------------------------------------------------------------------------------------------
102
HHSearch
63.90
20%
-83
- C2 -
1EP3
2
PYRDB_LACLM
A:
[9-288]
-
V
K
L
P
G
L
D
L
K
N
P
I
I
P
A
S
-
G
C
F
G
--------
F
G
-----
E
E
----
Y
A
K
Y
Y
D
--
L
-------
N
K
L
G
-
S
-
I
M
-------
V
K
-
A
T
T
L
H
PRFGNPTPR
V
A
E
T
AS
G
M
L
N
AI
G
L
--
Q
N
--
P
--------------------
G
------------------
L
-----------
E
V
--
I
M
T
E
K
L
P
W
L
N
E
----
N
F
P
E
L
P
I
I
A
N
V
A
G
S
------------------------
E
E
----------------------
A
D
Y
V
A
V
C
A
K
I
G
D
A
A
N
V
-
K
A
I
E
L
N
I
S
---------
C
---------
P
N
V
K
----
H
G
G
Q
A
F
G
T
D
P
E
V
A
A
A
L
V
K
A
C
K
A
V
S
--
K
V
--
P
L
Y
V
K
L
S
P
N
V
T
--------------
D
I
--
V
P
I
A
K
A
V
E
A
A
G
A
D
G
L
T
M
I
N
T
L
M
----------------------
G
V
R
F
D
LKTRQPILANI
T
G
--
G
L
----
S
G
----
P
AI
K
P
V
----
A
L
K
L
--
I
H
-
Q
V
A
Q
D
V
--
D
-----
I
P
I
I
G
M
G
G
V
A
N
A
Q
D
V
L
E
M
Y
M
-
A
G
A
S
A
V
A
V
G
T
A
N
F
A
-
D
P
F
V
C
P
K
I
I
D
K
L
P
----------------------------------------------------------------------------------------------
98
HHSearch
63.45
20%
-91
- C2 -
1JUB
6
PYRDA_LACLM
A:
[4-290]
-
T
T
F
A
N
A
K
F
A
N
P
F
M
N
A
S
-
G
V
H
C
--------
M
T
-----
I
E
----
D
L
E
E
L
K
--
A
-------
S
Q
A
G
-
A
-
Y
I
-------
T
K
-
S
S
T
L
E
---------------------
K
R
--
E
G
N-
P
LP------------------
R
Y
V
D
L
EL
G
S
I
N
SMGLPNLG
F
-----------
D
Y
--
Y
L
-
D
Y
V
---
L
K
N
Q
K
E
N
A
Q
E
G
P
I
F
F
S
I
A
G
M
------------------------
S
A
----------------------
A
E
N
I
A
M
L
K
K
I
Q
E
-
S
D
F
S
G
I
T
E
L
N
L
S
---------
C
---------
P
N
V
P
G
E
-----
P
Q
L
A
Y
D
F
E
A
T
E
K
L
L
K
E
V
F
T
F
F
--
T
K
--
P
L
G
V
K
L
P
P
Y
F
D
----
L
--------
V
H
F
--
D
I
M
A
E
I
L
N
Q
F
P
L
T
Y
V
N
S
V
N
S
I
G
N
G
L
F
I
DPEAESVVIKPKDG---
F
----------------
G
--
G
I
----
G
G
AYI
K
P
----
T
----
A
L
A
N
--
V
R
-
A
F
Y
T
R
L
KP
E
-----
I
Q
I
I
G
T
G
G
I
E
T
G
Q
D
A
F
E
H
L
L
-
C
G
A
T
M
L
Q
I
G
T
A
L
H
K
E
G
P
A
I
F
D
R
I
I
K
E
L
E
----------------------------------------------------------------------------------------------
86
HHSearch
62.78
19%
-91
- C2 -
3HGJ
2
?
A:
[7-336]
P
L
E
L
G
G
L
R
L
K
N
R
L
A
M
S
P
-
M
C
Q
Y
SATLEGEV
T
D
-----
W
H
----
L
L
H
Y
P
T
R
A
L
-------
G
G
V
G
-
L
-
I
L
-------
V
E
-
A
T
A
V
E
---------------------
P
L
--
G
R
--
I
--------------------
S
------------------
P
YDLGIWSEDH
L
P
---
G
L
-
K
E
L
A
R
-
R
I
----
R
E
A
G
A
V
P
G
I
Q
L
A
H
A
GRKAGTARPWEGGKPLGWRVVGP-
S
P
IPFDEGYPVPEPLD
E
A
G
M
E
R
I
L
Q
A
F
V
E
G
A
R
R
A
L
R
-
A
G
F
-
Q
V
I
E
L
H
M
A
---------
H
GY
L
L
S
S
F
L
S
P
L
S
N
Q
R
T
D
A
Y
G
G
S
L
E
N
R
M
R
F
P
L
Q
V
A
Q
A
V
R
E
V
V
PR
E
L
--
P
L
F
V
R
V
S
A
T
D
W
GEGG
W
----
S
--
L
E
D
T
--
L
A
F
A
R
R
L
K
E
L
G
V
D
L
L
D
C
S
S
G
G
V
----------------------
V
----------------
L
--
R
V
RIPL
A
P
----
G
----
F
----
Q
V
P
F
--
A
D
-
A
V
R
K
R
V
--
G
-----
L
R
T
G
A
V
G
L
I
T
T
P
E
Q
A
E
T
L
L
Q
A
G
S
A
D
L
V
L
L
G
R
V
L
L
R
-
D
P
Y
F
P
L
R
A
A
K
A
L
G
----------------------------------------------------------------------------------------------
84
HHSearch
61.10
21%
-89
- C2 -
3GR7
3
NAMA_GEOKA
A:
[8-326]
P
Y
T
I
R
G
L
T
L
K
N
R
I
V
M
S
P
-
M
C
M
Y
--------
S
C
DTKDG
A
V
R
T
W
H
K
I
H
Y
P
A
R
A
V
-------
G
Q
V
G
-
L
-
I
I
-------
V
E
-
A
T
G
V
T
---------------------
P
Q
--
G
R
--
I
SE------------------
R
DLGIWS------------
D
-----------
D
H
I
A
G
L
-
R
E
L
V
G
-
L
V
----
K
E
H
G
A
A
I
G
I
Q
L
A
H
A
GRKSQVP
G
E
I
I
A
PSAVPFDDSSP-
T
P
KEMT
K
A
D
I
E
E
T
V
----------
Q
A
F
Q
N
G
A
R
R
A
K
E
-
A
G
F
-
D
V
I
E
I
H
A
A
HGY
L
I
N
E
F
L
S
---------
P
L
S
N
R
R
Q
D
E
Y
G
G
S
P
E
N
R
Y
R
F
L
G
E
V
I
D
A
V
R
E
V
W
--
D
G
--
P
L
F
V
R
I
S
A
S
D
Y
----
H
PDGL
T
--
A
K
D
Y
--
V
P
Y
A
K
R
M
K
E
Q
G
V
D
L
V
D
V
S
S
G
A
I
----------------------
V
----------------
P
A
R
M
N
----
V
Y
P---
G
----
Y
----
Q
V
P
F
--
A
E
-
L
I
R
R
E
A
--
D
-----
I
P
T
G
A
V
G
L
I
T
S
G
W
Q
A
E
E
I
L
Q
N
G
R
A
D
L
V
F
L
G
R
E
L
L
R
-
N
P
Y
W
P
Y
A
A
A
R
E
L
G
A
---------------------------------------------------------------------------------------------